 The best thing to do is to work with your health care professional to figure out which one is going to be the best option for you. That way you can work through that together and choose the one that's going to be the most effective. And I think they'd like you to start testing in your mid-40s for this? Yes, around the age of 45. Again, if you have some of those risk factors, your health care professional may ask you to test earlier than that. If you have any symptoms, you definitely need to go in and be checked as well.