 feed on us humans. Dr. Matthew Lawrence with the University of Maryland School of Medicine says typically you'll notice symptoms two to six days later, but it could also take up to two weeks. While Lawrence says many people don't show symptoms, keep an eye out for a fever accompanied by a headache, body ache, joint pain, nausea, or a rash. And while it is rare, you could develop a neuroinvasive disease which can lead to death.