 The fact of the matter is that losing weight and keeping it off is really hard to do. So when a magic pill like Ozempic and other GLP-1 weight loss drugs come along, it seems like a dieter's dream come true. But is it? We now have a new kind of weight loss drug that works in a completely new way, that is an incredible transformation. The average person who uses Ozempic loses 15% of their body weight in a year.