 If you're traveling by car, it's best to hit the road in the morning. The transportation data company, INRIX, says peak traffic congestion varies by location, but the worst times to drive on or leading up to the holiday are generally between 2 p.m. and 7 p.m. Either way, be prepared for the roads to be jammed. INRIX transportation analyst, Bob Pishu, says road trips over the holiday week could take up to 67% longer than normal.