 Better Life with Dr. Sanjay Gupta. If you are lucky enough to take a big trip this year, have you given any thought to the jet lag? As someone who travels for work as much as I do, I can tell you it's a very real thing. In my 20-plus years as a journalist, I've come to find out that it just doesn't make sense to try and adjust your internal clock on quick trips. But on longer ones, experts we talked to had this advice.