 According to a May report from the U.S. Centers for Disease Control, synthetic opioids like fentanyl contribute to nearly 70 percent of overdose deaths. Officials believe they are only able to catch between 5 and 10 percent of the drugs smuggled into the U.S. Citing numbers from the port director in Nogales, Arizona, where the alert originated, the outlet notes that 45.8 million fentanyl pills were seized in 2023.