 Drug maker Pfizer moving forward with a daily weight loss pill. Here's ABC's Ariel Russia. Last winter, Pfizer decided to end a trial of a pill that you take twice a day after 50% of the participants reported experiencing side effects like nausea and vomiting. The company deciding to instead channel its efforts into creating a pill patients would only take once a day. Pfizer will develop the pill through the end of the year and will start trials after that before submitting it to the FDA for approval.