like a black see more but think of an expanding the nine-year plasma confines of the cranial there's no room in there as it starts growing as consumers related press on something vital in the brain and you could produce if it's not interrupted could produce death so benign neoplasms can kill generally by something going on mechanically ka nine-year plasmids as it's expanding locally again you think just about cartoon it's going to press on adjacent structures as it expands in that made the strongly adjacent structures just by sitting on it knock off the function of over one tissue or another selection b uh... quite significant and that's all based on our adjust the expansion of the benign neoplasm now i have mentioned local complications here these are sort of secondary things that may occur and they may be very important a benign neoplasm growing under a surface may expand to the point where the surface all straight silver then there may be hemorrhage could be trivial could really thought that they could be hemorrhage from such an australian area or there might be infection these are sort of secondary uh... complications of of the local mechanical situation uh... or the other thing is the uh... benign you pleasant unplug the plumbing so the wall of a doctor pressing on a vessel or something of that sort it can produce obstruction is very significant these are all sort of local effects there's one x sort of exception to this and i've listed systemic and the crying effects their runs something like this you had a good remember i told you the benign neoplasms are almost invariably very well differentiated mhm means they resemble a parental tissue you have a benign neoplasms arising from an end to the crime that is from the hormone secreting tissue it may well be so well differentiated that it mimics the adult issued by secreting a particular hormone that ordinarily comes from that issue the difference though is being autonomous and out of control of the body this tumor will produce gobs of that hormone and then the patient may present 