I'm going to describe our two published  studies in healthy volunteers characterizing mystical  experiences, go on to two ongoing studies in meditators, one in  novice meditators and one we're just about to undertake in  long-term meditators, and then I'll talk about two web-based  anonymous surveys in which we've been looking at the effects  of psilocybin when people ingest mushrooms in non-research  settings, and very briefly with some conclusions, implications, and  future directions. 