And you know they have a very distinctive characteristic don't they, they have round faces and they're short and they have slightly slanting eyes, etcetera etcetera, well these children have very marked physical erm appearance  they're fair haired and blue eyed  the reason for that is that this substance venial alanine is responsible for the production of pigment, so if that's interfered with they're going to be fair haired and blue eyed, they get eczema a lot, they have small heads and they have very widely spaced teeth, sorry down a bit , is that what you want?