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Abstract:

Objective To establish the validity and reliability of the Montreal Cognitive Assessment in Spanish ( MoCA - S ) to identify mild cognitive impairment ( MCI ) and dementia in the Mexican elderly population . Material and methods 168 participants from a memory clinic in Mexico City were enrolled and divided into 3 groups : 59 cognitively healthy ( CHG ) , 52 with mild cognitive impairment ( MCI )  ( DSM - 5 criteria ) and 57 with dementia ( NINCDS - ADRDA criteria ) . The MoCA - S and Mini - Mental State Evaluation ( MMSE ) were applied at baseline and during the last months to establish intra - observer reliability . ROC curves and a multinomial regression model were constructed to evaluate the effect of age and education on MoCA - S performance . Results The mean age of the participants was 76±8 .1 years and the education rate was 10 .7±5 .2 . The MoCA - S scores by group were : CHG , 27 .3±1 .9 ; MCI , 22 .9±2 .9 ; and dementia , 13 .7±4 .9 ( p<0 .001 ) . The reliability of the MoCA - S was 0 .89 and the intraclass correlation coefficient was 0 .955 . Sensitivity was 80% and specificity was 75% , with a cut - off point of 26 points for MCI ( area under the curve , 0 .886 ; p<0 .001 ) . For the dementia group , the sensitivity was 98% and specificity was 93% , with a cut - off point of 24points ( area under the curve , 0 .998 ; p<0 .001 ) . The multinomial regression showed no association with education and age for both the MCI and dementia groups . Conclusions The MoCA - S is a valid and reliable instrument for MCI and dementia screening in the Mexican population , even after adjusting for age and education .
mild cognitive impairment
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dementia
mild cognitive impairment
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dementia
dementia
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dementia
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MCI
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