You are an excellent assistant at finding disabilities in Spanish biomedical abstracts. You will be doing Named Entity Recognition for these disabilties and you must respond with each exact phrase as it appears in the article. If it appears multiple times, respond with each phrase separated by newline character. If there are no disabilities, respond with NA.

A disability is defined as:
a physical or mental condition that limits a person's movements, senses, or activities.


Abstract:

Objective To analyze the diagnostic accuracy of protón magnetic resonance spectroscopy ( 1H MRS ) in patients with cognitive impairment and to establish the usefulness of complementary information provided by conventional magnetic resonance imaging ( MRI ) . Material and methods 64 patients with cognitive impairment , including Alzheimer's disease ( AD )  ( n=31 ) , vascular dementia ( n=6 ) , mild cognitive impairment ( MCI )  ( n=9 ) , and major depression ( n=18 ) , were studied . All patients underwent cerebral MRI and single - volume 1H MRS using two echo times ( TE , 31 and 136 ms ) in the posterior cingulate gyrus and right temporal lobe . The metabolites analyzed were N - acetylaspartate ( NAA ) , myo - Inositol ( mi ) , choline ( Ch ) , and ere - atine ( Cr ) , and the ratios of Ch/Cr , mI/Cr , NAA/mIand NAA/Cr were calculated . In order to differentiate among the different types of cognitive impairment , the alterations in imaging and spectroscopy findings were graded from 0 to 4 , as was the mean combination of the two , and then ROC curves were obtained . Results Statistically significant differences were found between the spectra of patients with dementia ( AD and vascular dementia ) and those without dementia ( MCI and depression ) in the posterior cingulate gyrus . The NAA/ml ratio yielded the best área under the ROC curve , with the best sensitivity ( 82 .5% ) and specificity ( 72 .7% ) in the diagnosis of AD . The NAA/mI and ml/Cr quotients differentiated between the four degenerative pathologies causing the cognitive impairment . The combination of MRI and 1H MRS significantly improved the accuracy of the diagnosis of AD . Conclusions The metabolic differences found among patients with cognitive impairment using 1H MRS can be useful for differentiating AD , vascular dementia , MCI , and depression . The combination of spectroscopy and MRI findings is useful in the diagnosis of AD .
cognitive impairment
cognitive impairment
vascular dementia
mild cognitive impairment
MCI
cognitive impairment
dementia
vascular dementia
dementia
MCI
cognitive impairment
cognitive impairment
vascular dementia
MCI