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Abstract:

Introduction Few studies have validated the Spanish - language version of the Montreal Cognitive Assessment ( MoCA - S ) test in Latin American populations . Objetive To evaluate the psychometric properties and discriminant validity of the MoCA - S in elderly patients in Santiago de Chile . Methods 172 individuals were grouped according to their clinical diagnosis based on the Clinical Dementia Rating ( CDR ) scale as follows : amnestic mild cognitive impairment ( aMCI ; n±24 ) , non - amnestic MCI ( naMCI ; n±24 ) , mild dementia ( n±20 ) , and cognitively normal ( n±104 ) . Participants were evaluated with both the MoCA - S and the Mini–Mental State Examination ( MMSE ) to determine the discriminant validity of the MoCA - S . Results Mean age and years of schooling were 73±6 and 11±4 years , respectively , with no significant intergroup differences . The MoCA - S displayed good internal consistency ( Cronbach's α : 0 .772 ) , high inter - rater reliability ( Spearman correlation coefficient : 0 .846 ; P< .01 ) , and high intra - rater reliability ( test - retest reliability coefficient : 0 .922 ; P< .001 ) . The MoCA - S was found to be an effective and valid test for detecting aMCI ( AUC±0 .903 ) and mild dementia ( AUC±0 .957 ) ; its effectiveness for detecting naMCI was lower ( AUC±0 .629 ) . The optimal cut - off points for aMCI and mild dementia were<21 and<20 , respectively , with sensitivity and specificity rates of 75% and 82% for aMCI and 90% and 86% for mild dementia . The level of education had a great impact on scores : as a result , 2 points were added for patients with less than 8 years of schooling and one point for patients with 8 - 12 years of schooling ( MoCA - S1 - 2 ) . The MoCA - S1 - 2 showed significantly greater discriminant validity than the MMSE for differentiating aMCI from dementia . Conclusions The MoCA - S1 - 2 is a short , easy - to - use , and useful test for diagnosing aMCI and mild dementia .
amnestic mild cognitive impairment
aMCI
non - amnestic MCI
naMCI
mild dementia
aMCI
mild dementia
naMCI
aMCI
mild dementia
aMCI
mild dementia
dementia
aMCI
mild dementia