두피 건선 환자의 삶의 질에 미치는 국소 스테로이드제 단독 요법과 경구 사이클로스포린 병합 요법의 효과 비교 < 대한피부과학회 < KISS
홈 대한피부과학회> 대한피부과학회지> 두피 건선 환자의 삶의 질에 미치는 국소 스테로이드제 단독 요법과 경구 사이클로스포린 병합 요법의 효과 비교
두피 건선 환자의 삶의 질에 미치는 국소 스테로이드제 단독 요법과 경구 사이클로스포린 병합 요법의 효과 비교
Comparative Study of Quality of Life in Patients with Scalp Psoriasis Treated Using Topical Steroid Alone vs. Topical Steroid Combined with Cyclosporine
김민수 ( Minsu Kim ) , 양승걸 ( Seungkeol Yang ) , 김보리 ( Bo Ri Kim ) , 윤상웅 ( Sang Woong Youn )
페이지 : 513-518(6pages)
Background: Scalp psoriasis severely affects patients’ quality of life, and patients may occasionally be refractory to topical steroid application. Although systemic therapy combined with topical steroid application is recommended for treatment-resistant scalp psoriasis, previous research has not reported whether such combination treatment improves patients’ quality of life.
Objective: This study investigated whether combination therapy using oral cyclosporine and topical steroid reduces the severity of scalp psoriasis and improves patients’ quality of life compared with the use of topical steroid alone.
Results: No significant improvement was observed in the severity of psoriasis or in patients’ quality of life during the treatment period in patients receiving topical steroid alone. Patients treated with a combination of topical steroid and oral cyclosporine showed a reduction in the severity of psoriasis from the 4th week of treatment and their quality of life improved from the 12th week of treatment.
Conclusion: Combination therapy with oral cyclosporine and topical steroid may reduce the severity of scalp psoriasis and improve patients’ quality of life. (Korean J Dermatol 2019;57(9):513∼518)