<P> The twelfth season of the American television medical drama Grey 's Anatomy was ordered on May 7 , 2015 , by ABC . It premiered on September 24 , 2015 , in the United States on ABC . The twelfth season includes the show 's 250th episode , Guess Who 's Coming to Dinner , which is the fifth episode in the season . The season is produced by ABC Studios , in association with Shondaland Production Company and The Mark Gordon Company ; the showrunner being Shonda Rhimes . The season commenced airing with the episode `` Sledgehammer '' and concluded with `` Family Affair '' . </P>
<P> The twelfth season of the American television medical drama Grey 's Anatomy was ordered on May 7 , 2015 , by ABC . It premiered on September 24 , 2015 , in the United States on ABC . The twelfth season includes the show 's 250th episode , Guess Who 's Coming to Dinner , which is the fifth episode in the season . The season is produced by ABC Studios , in association with Shondaland Production Company and The Mark Gordon Company ; the showrunner being Shonda Rhimes . The season commenced airing with the episode `` Sledgehammer '' and concluded with `` Family Affair '' . </P>
when did season 12 of grey 's anatomy start
when did season 12 of grey 's anatomy start
September 24 , 2015
September 24 , 2015