<P> The first approved oxygen - carrying blood substitute was a perfluorocarbon - based product called Fluosol - DA - 20 , manufactured by Green Cross of Japan . It was approved by the Food and Drug Administration ( FDA ) in 1989 . Because of limited success , complexity of use and side effects , it was withdrawn in 1994 . However , Fluosol - DA remains the only oxygen therapeutic ever fully approved by the FDA . As of 2017 no haemoglobin - based product had been approved . </P>
<P> The first approved oxygen - carrying blood substitute was a perfluorocarbon - based product called Fluosol - DA - 20 , manufactured by Green Cross of Japan . It was approved by the Food and Drug Administration ( FDA ) in 1989 . Because of limited success , complexity of use and side effects , it was withdrawn in 1994 . However , Fluosol - DA remains the only oxygen therapeutic ever fully approved by the FDA . As of 2017 no haemoglobin - based product had been approved . </P>
when was the first synthetic blood approved for human use
when was the first synthetic blood approved for human use
1989
1989