<P> All of the centrally active opioid antagonists used widely in medicine are non-selective , either blocking multiple opioid receptors , or blocking the MOR but activating the KOR . However , for scientific research , selective antagonists are needed which can block one of the opioid receptors but without affecting the others . This has led to the development of antagonists which are highly selective to one of the four receptors : </P>
<P> All of the centrally active opioid antagonists used widely in medicine are non-selective , either blocking multiple opioid receptors , or blocking the MOR but activating the KOR . However , for scientific research , selective antagonists are needed which can block one of the opioid receptors but without affecting the others . This has led to the development of antagonists which are highly selective to one of the four receptors : </P>
opioid antagonists work by blocking the actions of
opioid antagonists work by blocking the actions of
either blocking multiple opioid receptors , or blocking the MOR
either blocking multiple opioid receptors , or blocking the MOR