<P> U.S. Route 42 ( US 42 ) is an east -- west United States highway that runs southwest - northeast for 355 miles ( 571 km ) from Louisville , Kentucky to Cleveland , Ohio . The route has several names including Pearl Road from Cleveland to Medina in Northeast Ohio , Reading Road in Cincinnati , Cincinnati and Lebanon Pike in southwestern Ohio and Brownsboro Road in Louisville . Traveling east , the highway ends in downtown Cleveland , Ohio ; and traveling west it ends in Louisville . </P>
<P> U.S. Route 42 ( US 42 ) is an east -- west United States highway that runs southwest - northeast for 355 miles ( 571 km ) from Louisville , Kentucky to Cleveland , Ohio . The route has several names including Pearl Road from Cleveland to Medina in Northeast Ohio , Reading Road in Cincinnati , Cincinnati and Lebanon Pike in southwestern Ohio and Brownsboro Road in Louisville . Traveling east , the highway ends in downtown Cleveland , Ohio ; and traveling west it ends in Louisville . </P>
where does us route 42 start and end
where does us route 42 start and end
Louisville , Kentucky to Cleveland , Ohio
Louisville , Kentucky to Cleveland , Ohio