<P> When the lining of a blood vessel is broken , platelets are attracted forming a platelet plug . These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules which in turn convert soluble fibrinogen in the serum into fibrin at the wound site . Fibrin forms long strands of tough insoluble protein that are bound to the platelets . Factor XIII completes the cross-linking of fibrin so that it hardens and contracts . The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot . </P>
<P> When the lining of a blood vessel is broken , platelets are attracted forming a platelet plug . These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules which in turn convert soluble fibrinogen in the serum into fibrin at the wound site . Fibrin forms long strands of tough insoluble protein that are bound to the platelets . Factor XIII completes the cross-linking of fibrin so that it hardens and contracts . The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot . </P>
the factor that is responsible for stabilizing a soluble firbrin monomer into an insoluble clot is
the factor that is responsible for stabilizing a soluble firbrin monomer into an insoluble clot is
Factor XIII
Factor XIII