<P> Okazaki fragments are short , newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication . They are complementary to the lagging template strand , together forming short double - stranded DNA sections . Okazaki fragments are between 1000 and 2000 nucleotides long in prokaryotes ( e.g. Escherichia coli ) and are roughly 100 to 200 nucleotides long in eukaryotes . They are separated by ~ 120 - nucleotide RNA primers and are unligated until RNA primers are removed , followed by enzyme ligase connecting ( ligating ) an Okazaki fragment onto the ( now continuous ) newly synthesized complementary strand . </P>
<P> Okazaki fragments are short , newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication . They are complementary to the lagging template strand , together forming short double - stranded DNA sections . Okazaki fragments are between 1000 and 2000 nucleotides long in prokaryotes ( e.g. Escherichia coli ) and are roughly 100 to 200 nucleotides long in eukaryotes . They are separated by ~ 120 - nucleotide RNA primers and are unligated until RNA primers are removed , followed by enzyme ligase connecting ( ligating ) an Okazaki fragment onto the ( now continuous ) newly synthesized complementary strand . </P>
which enzyme seals the gap between the okazaki fragments
which enzyme seals the gap between the okazaki fragments
ligase
ligase