<P> Substrate - level phosphorylation occurs in the cytoplasm of cells during glycolysis and in mitochondria either during the Krebs cycle or by MTHFD1L ( EC 6.3. 4.3 ) , an enzyme interconverting ADP + phosphate + 10 - formyltetrahydrofolate to ATP + formate + tetrahydrofolate ( reversibly ) , under both aerobic and anaerobic conditions . In the pay - off phase of glycolysis , a net of 2 ATP are produced by substrate - level phosphorylation . </P>
<P> Substrate - level phosphorylation occurs in the cytoplasm of cells during glycolysis and in mitochondria either during the Krebs cycle or by MTHFD1L ( EC 6.3. 4.3 ) , an enzyme interconverting ADP + phosphate + 10 - formyltetrahydrofolate to ATP + formate + tetrahydrofolate ( reversibly ) , under both aerobic and anaerobic conditions . In the pay - off phase of glycolysis , a net of 2 ATP are produced by substrate - level phosphorylation . </P>
where does the most substrate level phosphorylation occur
where does the most substrate level phosphorylation occur
in the cytoplasm of cells in mitochondria
in the cytoplasm of cells in mitochondria