<P> Fluoride was first added to toothpastes in the 1890s . Tanagra , containing calcium fluoride as the active ingredient , was sold by Karl F. Toellner Company , of Bremen , Germany , based upon the early work of chemist Albert Deninger . An analogous invention by Roy Cross , of Kansas City , Missouri , was initially criticized by the American Dental Association ( ADA ) in 1937 . Fluoride toothpastes developed in the 1950s received the ADA 's approval . To develop the first ADA - approved fluoride toothpaste , Procter & Gamble started a research program in the early 1940s . In 1950 , Procter & Gamble developed a joint research project team headed by Dr. Joseph Muhler at Indiana University to study new toothpaste with fluoride . In 1955 , Procter & Gamble 's Crest launched its first clinically proven fluoride - containing toothpaste . On August 1 , 1960 , the ADA reported that `` Crest has been shown to be an effective anticavity ( decay preventative ) dentifrice that can be of significant value when used in a conscientiously applied program of oral hygiene and regular professional care . '' </P>
<P> Fluoride was first added to toothpastes in the 1890s . Tanagra , containing calcium fluoride as the active ingredient , was sold by Karl F. Toellner Company , of Bremen , Germany , based upon the early work of chemist Albert Deninger . An analogous invention by Roy Cross , of Kansas City , Missouri , was initially criticized by the American Dental Association ( ADA ) in 1937 . Fluoride toothpastes developed in the 1950s received the ADA 's approval . To develop the first ADA - approved fluoride toothpaste , Procter & Gamble started a research program in the early 1940s . In 1950 , Procter & Gamble developed a joint research project team headed by Dr. Joseph Muhler at Indiana University to study new toothpaste with fluoride . In 1955 , Procter & Gamble 's Crest launched its first clinically proven fluoride - containing toothpaste . On August 1 , 1960 , the ADA reported that `` Crest has been shown to be an effective anticavity ( decay preventative ) dentifrice that can be of significant value when used in a conscientiously applied program of oral hygiene and regular professional care . '' </P>
when did they start putting fluoride in toothpaste
when did they start putting fluoride in toothpaste
the 1890s
the 1890s