<P> In mammals , gluconeogenesis has been believed to be restricted to the liver , the kidney , the intestine , and muscle , but recent evidence indicates gluconeogenesis occurring in astrocytes of the brain . These organs use somewhat different gluconeogenic precursors . The liver preferentially uses lactate , alanine and glycerol ( especially alanine ) while the kidney preferentially uses lactate , glutamine and glycerol ( especially glutamine ) . Lactate from the Cori cycle is quantitatively the largest source of substrate for gluconeogenesis , especially for the kidney . The liver uses both glycogenolysis and gluconeogenesis to produce glucose , whereas the kidney only uses gluconeogenesis . After a meal , the liver shifts to glycogen synthesis , whereas the kidney increases gluconeogenesis . The intestine uses mostly glutamine and glycerol . </P>
<P> In mammals , gluconeogenesis has been believed to be restricted to the liver , the kidney , the intestine , and muscle , but recent evidence indicates gluconeogenesis occurring in astrocytes of the brain . These organs use somewhat different gluconeogenic precursors . The liver preferentially uses lactate , alanine and glycerol ( especially alanine ) while the kidney preferentially uses lactate , glutamine and glycerol ( especially glutamine ) . Lactate from the Cori cycle is quantitatively the largest source of substrate for gluconeogenesis , especially for the kidney . The liver uses both glycogenolysis and gluconeogenesis to produce glucose , whereas the kidney only uses gluconeogenesis . After a meal , the liver shifts to glycogen synthesis , whereas the kidney increases gluconeogenesis . The intestine uses mostly glutamine and glycerol . </P>
where does gluconeogenesis take place in eukaryotic cells
where does gluconeogenesis take place in eukaryotic cells
liver kidney intestine muscle brain
liver kidney intestine muscle brain