<P> These intestinal lining cells can then either store the iron as ferritin , which is accomplished by Fe binding to apoferritin ( in which case the iron will leave the body when the cell dies and is sloughed off into feces ) , or the cell can release it into the body via the only known iron exporter in mammals , ferroportin . Hephaestin , a ferroxidase that can oxidize Fe to Fe and is found mainly in the small intestine , helps ferroportin transfer iron across the basolateral end of the intestine cells . In contrast , ferroportin is post-translationally repressed by hepcidin , a 25 - amino acid peptide hormone . The body regulates iron levels by regulating each of these steps . For instance , enterocytes synthesize more Dcytb , DMT1 and ferroportin in response to iron deficiency anemia . Iron absorption from diet is enhanced in the presence of vitamin C and diminished by excess calcium , zinc , or manganese . </P>
<P> These intestinal lining cells can then either store the iron as ferritin , which is accomplished by Fe binding to apoferritin ( in which case the iron will leave the body when the cell dies and is sloughed off into feces ) , or the cell can release it into the body via the only known iron exporter in mammals , ferroportin . Hephaestin , a ferroxidase that can oxidize Fe to Fe and is found mainly in the small intestine , helps ferroportin transfer iron across the basolateral end of the intestine cells . In contrast , ferroportin is post-translationally repressed by hepcidin , a 25 - amino acid peptide hormone . The body regulates iron levels by regulating each of these steps . For instance , enterocytes synthesize more Dcytb , DMT1 and ferroportin in response to iron deficiency anemia . Iron absorption from diet is enhanced in the presence of vitamin C and diminished by excess calcium , zinc , or manganese . </P>
where is iron absorbed in the small intestine
where is iron absorbed in the small intestine
the basolateral end of the intestine cells
the basolateral end of the intestine cells