<P> Acetylcholine is a neurotransmitter synthesized from dietary choline and acetyl - CoA ( ACoA ) , and is involved in the stimulation of muscle tissue in vertebrates as well as in some invertebrate animals . In vertebrate animals , the acetylcholine receptor subtype that is found at the neuromuscular junction of skeletal muscles is the nicotinic acetylcholine receptor ( nAChR ) , which is a ligand - gated ion channel . Each subunit of this receptor has a characteristic `` cys - loop '' , which is composed of a cysteine residue followed by 13 amino acid residues and another cysteine residue . The two cysteine residues form a disulfide linkage which results in the `` cys - loop '' receptor that is capable of binding acetylcholine and other ligands . These cys - loop receptors are found only in eukaryotes , but prokaryotes possess ACh receptors with similar properties . Not all species use a cholinergic neuromuscular junction ; e.g. crayfish and fruit flies have a glutamatergic neuromuscular junction . </P>
<P> Acetylcholine is a neurotransmitter synthesized from dietary choline and acetyl - CoA ( ACoA ) , and is involved in the stimulation of muscle tissue in vertebrates as well as in some invertebrate animals . In vertebrate animals , the acetylcholine receptor subtype that is found at the neuromuscular junction of skeletal muscles is the nicotinic acetylcholine receptor ( nAChR ) , which is a ligand - gated ion channel . Each subunit of this receptor has a characteristic `` cys - loop '' , which is composed of a cysteine residue followed by 13 amino acid residues and another cysteine residue . The two cysteine residues form a disulfide linkage which results in the `` cys - loop '' receptor that is capable of binding acetylcholine and other ligands . These cys - loop receptors are found only in eukaryotes , but prokaryotes possess ACh receptors with similar properties . Not all species use a cholinergic neuromuscular junction ; e.g. crayfish and fruit flies have a glutamatergic neuromuscular junction . </P>
the neurotransmitter used at the neuromuscular junction ( nmj ) is
the neurotransmitter used at the neuromuscular junction ( nmj ) is
Acetylcholine
Acetylcholine