<P> When the levels of collagen production and degradation equalize , the maturation phase of tissue repair is said to have begun . During maturation , type III collagen , which is prevalent during proliferation , is replaced by type I collagen . Originally disorganized collagen fibers are rearranged , cross-linked , and aligned along tension lines . The onset of the maturation phase may vary extensively , depending on the size of the wound and whether it was initially closed or left open , ranging from approximately 3 days to 3 weeks . The maturation phase can last for a year or longer , similarly depending on wound type . </P>
<P> When the levels of collagen production and degradation equalize , the maturation phase of tissue repair is said to have begun . During maturation , type III collagen , which is prevalent during proliferation , is replaced by type I collagen . Originally disorganized collagen fibers are rearranged , cross-linked , and aligned along tension lines . The onset of the maturation phase may vary extensively , depending on the size of the wound and whether it was initially closed or left open , ranging from approximately 3 days to 3 weeks . The maturation phase can last for a year or longer , similarly depending on wound type . </P>
which phase of healing begins about 3 weeks after injury
which phase of healing begins about 3 weeks after injury
the maturation phase
the maturation phase