[PAR] [TLE] Cardiac contractility modulation [SEP] Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV).  The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity by modulating (adjusting) the myocardial contractility.  The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES).  CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle. [PAR] [TLE] Artificial cardiac pacemaker [SEP] A pacemaker (or artificial pacemaker, so as not to be confused with the heart's natural pacemaker) is a medical device which uses electrical impulses, delivered by electrodes contracting the heart muscles, to regulate the beating of the heart.
[PAR] [TLE] Cardiac contractility modulation [ SEP ] Cardiac contractility modulation ( CCM ) is a treatment for patients with moderate to severe left ventricular systolic heart failure ( NYHA class II – IV ) . The short- and long - term use of this therapy enhances both the strength of ventricular contraction and the heart ’s pumping capacity by modulating ( adjusting ) the myocardial contractility . The CCM mechanism is based on stimulation of the cardiac muscle by non - excitatory electrical signals ( NES ) . CCM treatment is delivered by a pacemaker - like device that applies the NES , adjusted to and synchronized with the electrical action in the cardiac cycle . [PAR] [TLE] Artificial cardiac pacemaker [ SEP ] A pacemaker ( or artificial pacemaker , so as not to be confused with the heart 's natural pacemaker ) is a medical device which uses electrical impulses , delivered by electrodes contracting the heart muscles , to regulate the beating of the heart .
Cardiac contractility modulation a treatment for patients with moderate to severe left ventricular systolic heart failure and is delivered by a medical device which uses electrical impulses, delivered by electrodes contracting the heart muscles, to regulate what?
Cardiac contractility modulation a treatment for patients with moderate to severe left ventricular systolic heart failure and is delivered by a medical device which uses electrical impulses , delivered by electrodes contracting the heart muscles , to regulate what ?
the beating of the heart
the beating of the heart