<P> `` Losing My Religion '' is the twenty - seventh and final episode of the second season of the American television medical drama Grey 's Anatomy , and the show 's 36th episode overall . Written by Shonda Rhimes and directed by Mark Tinker , the episode was originally broadcast with `` Deterioration of the Fight or Flight Response '' , in a two - hour season finale event on the American Broadcasting Company ( ABC ) in the United States on May 15 , 2006 . Grey 's Anatomy centers around a group of young doctors in training . In this episode , Dr. Izzie Stevens ( Katherine Heigl ) and her fellow interns have to plan a prom for Dr. Richard Webber 's ( James Pickens , Jr . ) niece Camille Travis ( Tessa Thompson ) . Further storylines include Dr. Preston Burke ( Isaiah Washington ) recovering from his gunshot wound and Denny Duquette 's ( Jeffrey Dean Morgan ) death following his seemingly successful heart transplant surgery . </P>
<P> `` Losing My Religion '' is the twenty - seventh and final episode of the second season of the American television medical drama Grey 's Anatomy , and the show 's 36th episode overall . Written by Shonda Rhimes and directed by Mark Tinker , the episode was originally broadcast with `` Deterioration of the Fight or Flight Response '' , in a two - hour season finale event on the American Broadcasting Company ( ABC ) in the United States on May 15 , 2006 . Grey 's Anatomy centers around a group of young doctors in training . In this episode , Dr. Izzie Stevens ( Katherine Heigl ) and her fellow interns have to plan a prom for Dr. Richard Webber 's ( James Pickens , Jr . ) niece Camille Travis ( Tessa Thompson ) . Further storylines include Dr. Preston Burke ( Isaiah Washington ) recovering from his gunshot wound and Denny Duquette 's ( Jeffrey Dean Morgan ) death following his seemingly successful heart transplant surgery . </P>
when does denny from grey 's anatomy die
when does denny from grey 's anatomy die
`` Losing My Religion '' is the twenty - seventh and final episode of the second season
`` Losing My Religion '' is the twenty - seventh and final episode of the second season