<P> The prototypical depolarizing blocking drug is succinylcholine ( suxamethonium ) . It is the only such drug used clinically . It has a rapid onset ( 30 seconds ) but very short duration of action ( 5 -- 10 minutes ) because of hydrolysis by various cholinesterases ( such as butyrylcholinesterase in the blood ) . Succinylcholine was originally known as diacetylcholine because structurally it is composed of two acetylcholine molecules joined with a methyl group . Decamethonium is sometimes , but rarely , used in clinical practice . </P>
<P> The prototypical depolarizing blocking drug is succinylcholine ( suxamethonium ) . It is the only such drug used clinically . It has a rapid onset ( 30 seconds ) but very short duration of action ( 5 -- 10 minutes ) because of hydrolysis by various cholinesterases ( such as butyrylcholinesterase in the blood ) . Succinylcholine was originally known as diacetylcholine because structurally it is composed of two acetylcholine molecules joined with a methyl group . Decamethonium is sometimes , but rarely , used in clinical practice . </P>
the only depolarizing muscle relaxant in clinical use is
the only depolarizing muscle relaxant in clinical use is
succinylcholine
succinylcholine