<P> DNA ligase is a specific type of enzyme , a ligase , ( EC 6.5. 1.1 ) that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond . It plays a role in repairing single - strand breaks in duplex DNA in living organisms , but some forms ( such as DNA ligase IV ) may specifically repair double - strand breaks ( i.e. a break in both complementary strands of DNA ) . Single - strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template , with DNA ligase creating the final phosphodiester bond to fully repair the DNA . </P>
<P> DNA ligase is a specific type of enzyme , a ligase , ( EC 6.5. 1.1 ) that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond . It plays a role in repairing single - strand breaks in duplex DNA in living organisms , but some forms ( such as DNA ligase IV ) may specifically repair double - strand breaks ( i.e. a break in both complementary strands of DNA ) . Single - strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template , with DNA ligase creating the final phosphodiester bond to fully repair the DNA . </P>
which class of the enzymes can be used to join two fragments of dna
which class of the enzymes can be used to join two fragments of dna
DNA ligase
DNA ligase