<P> Cy Young holds the MLB win record with 511 ; Walter Johnson is second with 417 . Young and Johnson are the only players to earn 400 or more wins . Among pitchers whose entire careers were in the post-1920 live - ball era , Warren Spahn has the most wins with 363 . Only 24 pitchers have accumulated 300 or more wins in their careers . Roger Clemens is the only pitcher with 300 wins or more not elected to the National Baseball Hall of Fame . </P>
<P> Cy Young holds the MLB win record with 511 ; Walter Johnson is second with 417 . Young and Johnson are the only players to earn 400 or more wins . Among pitchers whose entire careers were in the post-1920 live - ball era , Warren Spahn has the most wins with 363 . Only 24 pitchers have accumulated 300 or more wins in their careers . Roger Clemens is the only pitcher with 300 wins or more not elected to the National Baseball Hall of Fame . </P>
most wins by a pitcher in major league baseball
most wins by a pitcher in major league baseball
Cy Young holds the MLB win record with 511
Cy Young holds the MLB win record with 511