<P> Most of the supervillains of Spider - Man would be introduced in The Amazing Spider - Man comic book starting with the Chameleon . The early villains would be introduced in the 1960s in the Silver Age of Comic Books , and created by Stan Lee and Steve Ditko . John Romita , Sr. replaced Ditko starting with the Rhino . Gerry Conway later replaced Stan Lee and helped create new adversaries for the web - slinger and also helped pave the way to the Bronze Age of Comic Books with the death of Spider - Man 's long time romantic interest , Gwen Stacy . Many collaborators would soon take over The Amazing Spider - Man title . One of the more popular examples included Todd McFarlane 's Venom in the Modern Age of Comic Books . </P>
<P> Most of the supervillains of Spider - Man would be introduced in The Amazing Spider - Man comic book starting with the Chameleon . The early villains would be introduced in the 1960s in the Silver Age of Comic Books , and created by Stan Lee and Steve Ditko . John Romita , Sr. replaced Ditko starting with the Rhino . Gerry Conway later replaced Stan Lee and helped create new adversaries for the web - slinger and also helped pave the way to the Bronze Age of Comic Books with the death of Spider - Man 's long time romantic interest , Gwen Stacy . Many collaborators would soon take over The Amazing Spider - Man title . One of the more popular examples included Todd McFarlane 's Venom in the Modern Age of Comic Books . </P>
who was the first villain spider man fought
who was the first villain spider man fought
Chameleon
Chameleon