<P> Chief Opechancanough organized and led a well - coordinated series of surprise attacks on multiple English settlements along both sides of a 50 - mile ( 80 km ) long stretch of the James River , which took place early on the morning of March 22 , 1622 . This event came to be known as the Indian Massacre of 1622 and resulted in the deaths of 347 colonists ( including men , women , and children ) and the abduction of many others . The Massacre caught most of the Virginia Colony by surprise and virtually wiped out several entire communities , including Henricus and Wolstenholme Town at Martin 's Hundred . </P>
<P> Chief Opechancanough organized and led a well - coordinated series of surprise attacks on multiple English settlements along both sides of a 50 - mile ( 80 km ) long stretch of the James River , which took place early on the morning of March 22 , 1622 . This event came to be known as the Indian Massacre of 1622 and resulted in the deaths of 347 colonists ( including men , women , and children ) and the abduction of many others . The Massacre caught most of the Virginia Colony by surprise and virtually wiped out several entire communities , including Henricus and Wolstenholme Town at Martin 's Hundred . </P>
who organized the native resistance to the british
who organized the native resistance to the british
Chief Opechancanough
Chief Opechancanough