<P> Susan Murphy ( Reese Witherspoon ) of Modesto , California is going to be married to news weatherman Derek Dietl ( Paul Rudd ) . But before the ceremony , she gets hit by a meteorite and its energy causes her to grow uncontrollably during the ceremony . As a side - effect , her hair turns white . She is tranquilized by the military and awakens in a top secret government facility that houses monsters of which the public is ignorant . She meets General W.R. Monger ( Kiefer Sutherland ) , the Army officer in charge of the facility , and her fellow monster inmates : Dr. Cockroach P.H.D. ( Hugh Laurie ) , a mad scientist who became half - human , half - cockroach after an experiment ; B.O.B. ( Benzoate Ostylezene Bicarbonate ) ( Seth Rogen ) , a brainless , living mass of goo as a result of a food flavoring mutation ; Insectosaurus , a massive mutated bug standing 350 feet in height , and the Missing Link ( Will Arnett ) , a prehistoric fish - ape hybrid who was thawed from deep ice . Susan herself has been renamed to Ginormica . </P>
<P> Susan Murphy ( Reese Witherspoon ) of Modesto , California is going to be married to news weatherman Derek Dietl ( Paul Rudd ) . But before the ceremony , she gets hit by a meteorite and its energy causes her to grow uncontrollably during the ceremony . As a side - effect , her hair turns white . She is tranquilized by the military and awakens in a top secret government facility that houses monsters of which the public is ignorant . She meets General W.R. Monger ( Kiefer Sutherland ) , the Army officer in charge of the facility , and her fellow monster inmates : Dr. Cockroach P.H.D. ( Hugh Laurie ) , a mad scientist who became half - human , half - cockroach after an experiment ; B.O.B. ( Benzoate Ostylezene Bicarbonate ) ( Seth Rogen ) , a brainless , living mass of goo as a result of a food flavoring mutation ; Insectosaurus , a massive mutated bug standing 350 feet in height , and the Missing Link ( Will Arnett ) , a prehistoric fish - ape hybrid who was thawed from deep ice . Susan herself has been renamed to Ginormica . </P>
who plays the general in monsters vs aliens
who plays the general in monsters vs aliens
Kiefer Sutherland
Kiefer Sutherland