<P> The river then follows a roughly southwest and then west - northwest course until Cincinnati , before bending to a west - southwest course for most of its length . The course forms the northern borders of West Virginia and Kentucky ; and the southern borders of Ohio , Indiana and Illinois , until it joins the Mississippi River near the city of Cairo , Illinois . </P>
<P> The river then follows a roughly southwest and then west - northwest course until Cincinnati , before bending to a west - southwest course for most of its length . The course forms the northern borders of West Virginia and Kentucky ; and the southern borders of Ohio , Indiana and Illinois , until it joins the Mississippi River near the city of Cairo , Illinois . </P>
where does the ohio river meet the mississippi river
where does the ohio river meet the mississippi river
near the city of Cairo , Illinois
near the city of Cairo , Illinois