<P> The nucleolus ( / njuːˈkliːələs / or / ˌnjuːkliˈoʊləs / , plural nucleoli / njuːˈkliːəˌlaɪ / or / ˌnjuːkliˈoʊlaɪ / ) is the largest structure in the nucleus of eukaryotic cells . It is best known as the site of ribosome biogenesis . Nucleoli also participate in the formation of signal recognition particles and play a role in the cell 's response to stress . Nucleoli are made of proteins , DNA and RNA and form around specific chromosomal regions called nucleolar organizing regions . Malfunction of nucleoli can be the cause of several human conditions called `` nucleolopathies '' and the nucleolus is being investigated as a target for cancer chemotherapy . </P>
<P> The nucleolus ( / njuːˈkliːələs / or / ˌnjuːkliˈoʊləs / , plural nucleoli / njuːˈkliːəˌlaɪ / or / ˌnjuːkliˈoʊlaɪ / ) is the largest structure in the nucleus of eukaryotic cells . It is best known as the site of ribosome biogenesis . Nucleoli also participate in the formation of signal recognition particles and play a role in the cell 's response to stress . Nucleoli are made of proteins , DNA and RNA and form around specific chromosomal regions called nucleolar organizing regions . Malfunction of nucleoli can be the cause of several human conditions called `` nucleolopathies '' and the nucleolus is being investigated as a target for cancer chemotherapy . </P>
where is the nucleolus found in an animal cell
where is the nucleolus found in an animal cell
nucleus
nucleus