<P> The production of lysosomal proteins suggests one method of lysosome sustainment . Lysosomal protein genes are transcribed in the nucleus . mRNA transcripts exit the nucleus into the cytosol , where they are translated by ribosomes . The nascent peptide chains are translocated into the rough endoplasmic reticulum , where they are modified . Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport , a specific lysosomal tag , mannose 6 - phosphate , is added to the peptides . The presence of these tags allow for binding to mannose 6 - phosphate receptors in the Golgi apparatus , a phenomenon that is crucial for proper packaging into vesicles destined for the lysosomal system . </P>
<P> The production of lysosomal proteins suggests one method of lysosome sustainment . Lysosomal protein genes are transcribed in the nucleus . mRNA transcripts exit the nucleus into the cytosol , where they are translated by ribosomes . The nascent peptide chains are translocated into the rough endoplasmic reticulum , where they are modified . Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport , a specific lysosomal tag , mannose 6 - phosphate , is added to the peptides . The presence of these tags allow for binding to mannose 6 - phosphate receptors in the Golgi apparatus , a phenomenon that is crucial for proper packaging into vesicles destined for the lysosomal system . </P>
which organelle makes the digestive enzymes of lysosome
which organelle makes the digestive enzymes of lysosome
the Golgi apparatus
the Golgi apparatus