<P> Characterized by Rhimes as a dork with issues expressing her feelings , Lexie 's focal storyline in the series involved her romantic relationship with plastics attending Mark Sloan ( Eric Dane ) . Both she and Mark sustained life - threatening injuries during an aviation accident in the eighth - season finale , which resulted in their deaths . Seattle Grace Mercy West is later renamed Grey - Sloan Memorial Hospital in their memory . The reason given for Lexie 's departure after five years on the show was Leigh 's desire to spend more time with her family . </P>
<P> Characterized by Rhimes as a dork with issues expressing her feelings , Lexie 's focal storyline in the series involved her romantic relationship with plastics attending Mark Sloan ( Eric Dane ) . Both she and Mark sustained life - threatening injuries during an aviation accident in the eighth - season finale , which resulted in their deaths . Seattle Grace Mercy West is later renamed Grey - Sloan Memorial Hospital in their memory . The reason given for Lexie 's departure after five years on the show was Leigh 's desire to spend more time with her family . </P>
when does lexie grey leave grey 's anatomy
when does lexie grey leave grey 's anatomy
the eighth - season finale
the eighth - season finale