<Ul> <Li> Most seasons leading league : 8 , Jim Brown , 1957 -- 1961 1963 -- 1965 </Li> <Li> Most consecutive seasons leading league : 5 , Jim Brown , 1957 -- 1961 </Li> <Li> Most rushing yards per game average , career : 104.3 , Jim Brown , 1957 -- 1965 </Li> <Li> Most yards gained , career : 18,355 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most seasons , 500 + yards rushing : 14 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most seasons , 1,000 + yards rushing : 11 , Emmitt Smith , 1991 -- 2001 </Li> <Li> Most seasons , 1,500 + yards rushing : 5 , Barry Sanders , 1991 -- 1997 </Li> <Li> Most consecutive seasons , 500 + yards rushing : 13 , Walter Payton , 1975 -- 1987 , Emmitt Smith 1990 -- 2002 , Frank Gore 2005 -- 2017 </Li> <Li> Most consecutive seasons , 1,000 + yards rushing : 11 , Emmitt Smith , 1991 -- 2001 </Li> <Li> Most consecutive seasons , 1,500 + yards rushing : 4 , Barry Sanders , 1994 -- 1997 </Li> <Li> Most yards gained , season : 2,105 , Eric Dickerson 1984 </Li> <Li> Most yards gained , no fumbles , season : 1,883 , Barry Sanders , 1994 </Li> <Li> Most yards gained , rookie , season : 1,808 Eric Dickerson , 1983 </Li> <Li> Most yards , no touchdowns , season : 956 , Joe Washington , 1978 </Li> <Li> Most yards gained , no rushing touchdowns , game : 237 , Barry Sanders , November 13 , 1994 </Li> <Li> Most yards gained , season , at Home : 1,125 Walter Payton , 1977 </Li> <Li> Most yards gained , season , Away : 1,087 Eric Dickerson , 1984 </Li> <Li> Most yards gained , back - to - back games : 476 , O.J. Simpson Nov 25 , 1976 - Dec 5 , 1976 </Li> <Li> Most yards gained , back - to - back games , 7 days apart : 467 , Walter Payton Nov 13 , 1977 - Nov 20 , 1977 </Li> <Li> Most yards gained , back - to - back games , 4 days apart : 412 , Walter Payton Nov 20 , 1977 - Nov 24 , 1977 </Li> <Li> Most yards gained , game : 296 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , outdoor game : 295 , Jamal Lewis Sep 14 , 2003 </Li> <Li> Most yards gained , away game : 286 , Jerome Harrison Dec 20 , 2009 </Li> <Li> Most yards gained , one half : 253 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , first game : 194 , Alan Ameche Sep 25 , 1955 </Li> <Li> Most yards gained , game , rookie : 296 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , one quarter : 165 , Jamaal Charles Dec 23 , 2012 </Li> <Li> Longest run from scrimmage : 99 yard ( touchdown ) , Tony Dorsett , January 3 , 1983 </Li> <Li> Highest yards gained per game average , career : 104.3 , Jim Brown , 1957 -- 1965 </Li> <Li> Highest yards gained per game average , season : 143.1 , O.J. Simpson , 1973 </Li> <Li> Highest average gain , game ( minimum 100 yards ) : 52.50 ( 2 carries , 105 yards ) , Brian Mitchell Oct 1 , 2000 </Li> <Li> Most games , 50 + yards rushing , career : 173 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most games , 100 + yards rushing , career : 78 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most games , 150 + yards rushing , career : 25 , Barry Sanders , 1989 -- 1998 </Li> <Li> Most games , 200 + yards rushing , career : 6 , O.J. Simpson , 1969 -- 1979 ; Adrian Peterson , 2007 -- 2015 </Li> <Li> Most games , 250 + yards rushing , career : 2 , O.J. Simpson , 1973 -- 1976 </Li> <Li> Most games , 100 + yards rushing , season : 14 , Barry Sanders , 1997 </Li> <Li> Most games , 150 + yards rushing , season : 7 , Earl Campbell , 1980 , Adrian Peterson 2012 </Li> <Li> Most games , 200 + yards rushing , season : 4 , Earl Campbell , 1980 </Li> <Li> Most consecutive games , 50 + yards rushing : 38 , Priest Holmes , 2001 -- 2003 </Li> <Li> Most consecutive games , 100 + yards rushing : 14 , Barry Sanders , 1997 </Li> <Li> Most consecutive games
<Ul> <Li> Most seasons leading league : 8 , Jim Brown , 1957 -- 1961 1963 -- 1965 </Li> <Li> Most consecutive seasons leading league : 5 , Jim Brown , 1957 -- 1961 </Li> <Li> Most rushing yards per game average , career : 104.3 , Jim Brown , 1957 -- 1965 </Li> <Li> Most yards gained , career : 18,355 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most seasons , 500 + yards rushing : 14 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most seasons , 1,000 + yards rushing : 11 , Emmitt Smith , 1991 -- 2001 </Li> <Li> Most seasons , 1,500 + yards rushing : 5 , Barry Sanders , 1991 -- 1997 </Li> <Li> Most consecutive seasons , 500 + yards rushing : 13 , Walter Payton , 1975 -- 1987 , Emmitt Smith 1990 -- 2002 , Frank Gore 2005 -- 2017 </Li> <Li> Most consecutive seasons , 1,000 + yards rushing : 11 , Emmitt Smith , 1991 -- 2001 </Li> <Li> Most consecutive seasons , 1,500 + yards rushing : 4 , Barry Sanders , 1994 -- 1997 </Li> <Li> Most yards gained , season : 2,105 , Eric Dickerson 1984 </Li> <Li> Most yards gained , no fumbles , season : 1,883 , Barry Sanders , 1994 </Li> <Li> Most yards gained , rookie , season : 1,808 Eric Dickerson , 1983 </Li> <Li> Most yards , no touchdowns , season : 956 , Joe Washington , 1978 </Li> <Li> Most yards gained , no rushing touchdowns , game : 237 , Barry Sanders , November 13 , 1994 </Li> <Li> Most yards gained , season , at Home : 1,125 Walter Payton , 1977 </Li> <Li> Most yards gained , season , Away : 1,087 Eric Dickerson , 1984 </Li> <Li> Most yards gained , back - to - back games : 476 , O.J. Simpson Nov 25 , 1976 - Dec 5 , 1976 </Li> <Li> Most yards gained , back - to - back games , 7 days apart : 467 , Walter Payton Nov 13 , 1977 - Nov 20 , 1977 </Li> <Li> Most yards gained , back - to - back games , 4 days apart : 412 , Walter Payton Nov 20 , 1977 - Nov 24 , 1977 </Li> <Li> Most yards gained , game : 296 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , outdoor game : 295 , Jamal Lewis Sep 14 , 2003 </Li> <Li> Most yards gained , away game : 286 , Jerome Harrison Dec 20 , 2009 </Li> <Li> Most yards gained , one half : 253 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , first game : 194 , Alan Ameche Sep 25 , 1955 </Li> <Li> Most yards gained , game , rookie : 296 , Adrian Peterson Nov 4 , 2007 </Li> <Li> Most yards gained , one quarter : 165 , Jamaal Charles Dec 23 , 2012 </Li> <Li> Longest run from scrimmage : 99 yard ( touchdown ) , Tony Dorsett , January 3 , 1983 </Li> <Li> Highest yards gained per game average , career : 104.3 , Jim Brown , 1957 -- 1965 </Li> <Li> Highest yards gained per game average , season : 143.1 , O.J. Simpson , 1973 </Li> <Li> Highest average gain , game ( minimum 100 yards ) : 52.50 ( 2 carries , 105 yards ) , Brian Mitchell Oct 1 , 2000 </Li> <Li> Most games , 50 + yards rushing , career : 173 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most games , 100 + yards rushing , career : 78 , Emmitt Smith , 1990 -- 2004 </Li> <Li> Most games , 150 + yards rushing , career : 25 , Barry Sanders , 1989 -- 1998 </Li> <Li> Most games , 200 + yards rushing , career : 6 , O.J. Simpson , 1969 -- 1979 ; Adrian Peterson , 2007 -- 2015 </Li> <Li> Most games , 250 + yards rushing , career : 2 , O.J. Simpson , 1973 -- 1976 </Li> <Li> Most games , 100 + yards rushing , season : 14 , Barry Sanders , 1997 </Li> <Li> Most games , 150 + yards rushing , season : 7 , Earl Campbell , 1980 , Adrian Peterson 2012 </Li> <Li> Most games , 200 + yards rushing , season : 4 , Earl Campbell , 1980 </Li> <Li> Most consecutive games , 50 + yards rushing : 38 , Priest Holmes , 2001 -- 2003 </Li> <Li> Most consecutive games , 100 + yards rushing : 14 , Barry Sanders , 1997 </Li> <Li> Most consecutive games
who holds record for most rushing yards in nfl game
who holds record for most rushing yards in nfl game
Adrian Peterson
Adrian Peterson