<P> In the brain , norepinephrine is produced in nuclei that are small yet exert powerful effects on other brain areas . The most important of these nuclei is the locus coeruleus , located in the pons . Outside the brain , norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen , and it is also released directly into the bloodstream by the adrenal glands . Regardless of how and where it is released , norepinephrine acts on target cells by binding to and activating noradrenergic receptors located on the cell surface . </P>
<P> In the brain , norepinephrine is produced in nuclei that are small yet exert powerful effects on other brain areas . The most important of these nuclei is the locus coeruleus , located in the pons . Outside the brain , norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen , and it is also released directly into the bloodstream by the adrenal glands . Regardless of how and where it is released , norepinephrine acts on target cells by binding to and activating noradrenergic receptors located on the cell surface . </P>
how does the same neurotransmitter ( i.s. norepinephrine ) have different effects on different tissues
how does the same neurotransmitter ( i.s. norepinephrine ) have different effects on different tissues
norepinephrine acts on target cells by binding to and activating noradrenergic receptors
norepinephrine acts on target cells by binding to and activating noradrenergic receptors