<Ul> <Li> Abby ( Danica McKellar ) and Martha ( Jen Drohan ) : two ladies that Raj and Sheldon meet at a university mixer . Abby takes a liking to Raj and Martha takes a liking to Sheldon . While Raj is welcoming of Abby 's moves , Sheldon is rejective of Martha 's moves . </Li> <Li> Alice ( Courtney Ford ) : an attractive comic book enthusiast whom Leonard meets after Priya moves back to India . Meeting Alice triggers a chain of events which ends with Leonard and Priya breaking up . </Li> <Li> Mandy Chao ( Melissa Tang ) : a colleague of Leonard at the university who made out with him once when they were both drunk . The incident , which happened prior to Leonard 's marriage to Penny , almost sabotages the marriages after Leonard tells Penny about it . </Li> <Li> Chen ( James Hong ) : a maitre d ' at a Chinese restaurant that the guys eat at . </Li> <Li> Professor Crawley ( Lewis Black ) : a former entomologist at the university with whom Sheldon , Howard , and Raj confer about a cricket . </Li> <Li> Issabella Maria Concepcion ( Maria Canals - Barrera ) a Cuban - American janitor working in Raj 's telescope building whom Raj wants to date . </Li> <Li> Kenny Fitzgerald ( Michael Rapaport ) : an intelligent thief who sells stolen liquid helium to Leonard and Sheldon . He later strikes up a friendship with the duo and they watch Ernest Goes to Jail together . </Li> <Li> Mrs. Fowler ( Annie O'Donnell ; Kathy Bates ) : Amy 's mother , who is played by Annie O'Donnell in `` The Desperation Emanation '' , and by Kathy Bates in `` The Bow Tie Asymmetry '' . </Li> <Li> Dr. Gallo ( Jane Kaczmarek ) : a therapist to whom Penny attempts to sell products . She winds up conducting therapy on both Penny and Leonard . </Li> <Li> Mrs. Latham ( Jessica Walter ) : a donor for the university who goes out on two dates with Leonard . </Li> <Li> Toby Loobenfield ( DJ Qualls ) : a scientist at CalTech whom Sheldon hires to play his fictional drug - addicted cousin Leo . </Li> <Li> Dr. Oliver Lorvis ( Billy Bob Thornton ) : a medical doctor to whom Penny sells products . He misreads her flirtations and locks the guys in his basement while he goes to woo her ( as well as Amy and Bernadette ) . </Li> </Ul>
<Ul> <Li> Abby ( Danica McKellar ) and Martha ( Jen Drohan ) : two ladies that Raj and Sheldon meet at a university mixer . Abby takes a liking to Raj and Martha takes a liking to Sheldon . While Raj is welcoming of Abby 's moves , Sheldon is rejective of Martha 's moves . </Li> <Li> Alice ( Courtney Ford ) : an attractive comic book enthusiast whom Leonard meets after Priya moves back to India . Meeting Alice triggers a chain of events which ends with Leonard and Priya breaking up . </Li> <Li> Mandy Chao ( Melissa Tang ) : a colleague of Leonard at the university who made out with him once when they were both drunk . The incident , which happened prior to Leonard 's marriage to Penny , almost sabotages the marriages after Leonard tells Penny about it . </Li> <Li> Chen ( James Hong ) : a maitre d ' at a Chinese restaurant that the guys eat at . </Li> <Li> Professor Crawley ( Lewis Black ) : a former entomologist at the university with whom Sheldon , Howard , and Raj confer about a cricket . </Li> <Li> Issabella Maria Concepcion ( Maria Canals - Barrera ) a Cuban - American janitor working in Raj 's telescope building whom Raj wants to date . </Li> <Li> Kenny Fitzgerald ( Michael Rapaport ) : an intelligent thief who sells stolen liquid helium to Leonard and Sheldon . He later strikes up a friendship with the duo and they watch Ernest Goes to Jail together . </Li> <Li> Mrs. Fowler ( Annie O'Donnell ; Kathy Bates ) : Amy 's mother , who is played by Annie O'Donnell in `` The Desperation Emanation '' , and by Kathy Bates in `` The Bow Tie Asymmetry '' . </Li> <Li> Dr. Gallo ( Jane Kaczmarek ) : a therapist to whom Penny attempts to sell products . She winds up conducting therapy on both Penny and Leonard . </Li> <Li> Mrs. Latham ( Jessica Walter ) : a donor for the university who goes out on two dates with Leonard . </Li> <Li> Toby Loobenfield ( DJ Qualls ) : a scientist at CalTech whom Sheldon hires to play his fictional drug - addicted cousin Leo . </Li> <Li> Dr. Oliver Lorvis ( Billy Bob Thornton ) : a medical doctor to whom Penny sells products . He misreads her flirtations and locks the guys in his basement while he goes to woo her ( as well as Amy and Bernadette ) . </Li> </Ul>
who plays amy farrah fowler 's mother on big bang
who plays amy farrah fowler 's mother on big bang
Annie O'Donnell Kathy Bates
Annie O'Donnell Kathy Bates