<P> Rhimes also described the difficulty she faced in finding an appropriate love interest for the character of Alex Karev : `` We kept meeting with people and it was n't until we met Elizabeth Reaser and sat down with her , and in two seconds in realized that she was absolutely the one we 'd been looking for . '' Reaser explained that when she was cast , there were no definite plans for the development of her character , and that only the intrigue of the ferry accident had been explained to her . She also deemed her character `` frustrated and scared '' . As for the make up process , Reaser stated : `` The prosthetic changes your outlook on yourself . It can be very disorienting . It 's intense . '' Beers , however , noted that the focus on Ava was mainly due to her inability to express her feelings through facial expressions , only communicating with her eyes and voice . Executive producer Rob Corn stated that his plan for the original arc was about Jane Doe 's inner life , struggling to get out of the situation she is trapped in . He stated that the main characteristics they had been looking for in the actress for the part were strength and vulnerability . He also called Reaser 's performance `` heart - wrenching and wonderful '' . Betsy Beers , the show 's supervising executive producer , found Izzie to have been marked for life by Denny 's death , which matured her `` in a very sobering way '' , but played a major role in making her feel more confident . She also noted the undeniable connection between Izzie and Alex Karev , whose desire to do honorable things has been compared with his `` cutting and sarcastic '' personality . After Izzie 's continuous efforts to change Alex during their relationship in the previous season , Beers announced the possibility of a relationship between the two of them . She also contrasted the female leads on the show with women in film , explaining how the characters on television are shaped in unique ways . </P>
<P> Rhimes also described the difficulty she faced in finding an appropriate love interest for the character of Alex Karev : `` We kept meeting with people and it was n't until we met Elizabeth Reaser and sat down with her , and in two seconds in realized that she was absolutely the one we 'd been looking for . '' Reaser explained that when she was cast , there were no definite plans for the development of her character , and that only the intrigue of the ferry accident had been explained to her . She also deemed her character `` frustrated and scared '' . As for the make up process , Reaser stated : `` The prosthetic changes your outlook on yourself . It can be very disorienting . It 's intense . '' Beers , however , noted that the focus on Ava was mainly due to her inability to express her feelings through facial expressions , only communicating with her eyes and voice . Executive producer Rob Corn stated that his plan for the original arc was about Jane Doe 's inner life , struggling to get out of the situation she is trapped in . He stated that the main characteristics they had been looking for in the actress for the part were strength and vulnerability . He also called Reaser 's performance `` heart - wrenching and wonderful '' . Betsy Beers , the show 's supervising executive producer , found Izzie to have been marked for life by Denny 's death , which matured her `` in a very sobering way '' , but played a major role in making her feel more confident . She also noted the undeniable connection between Izzie and Alex Karev , whose desire to do honorable things has been compared with his `` cutting and sarcastic '' personality . After Izzie 's continuous efforts to change Alex during their relationship in the previous season , Beers announced the possibility of a relationship between the two of them . She also contrasted the female leads on the show with women in film , explaining how the characters on television are shaped in unique ways . </P>
who plays jane doe in grey 's anatomy season 3
who plays jane doe in grey 's anatomy season 3
Elizabeth Reaser
Elizabeth Reaser