<Table> <Tr> <Th> Year / period </Th> <Th> Type of event </Th> <Th> Event </Th> <Th> Location </Th> </Tr> <Tr> <Td> 1761 </Td> <Td> Development </Td> <Td> Italian anatomist Giovanni Battista Morgagni is attributed with the first known description of pancreatic cancer in his publication De Sedibus Et Causis Morborum Per Anatomen Indagatis Libri Quinque . </Td> <Td> </Td> </Tr> <Tr> <Td> 1858 </Td> <Td> Development </Td> <Td> American physician Jacob Mendez Da Costa describes the first microscopic diagnosis of adenocarcinoma , manifesting pancreatic cancer as a true disease entity . </Td> <Td> </Td> </Tr> <Tr> <Td> 1898 </Td> <Td> Development </Td> <Td> Italian surgeon Alessandro Codivilla performs the first reported attempt at a pancreaticoduodenectomy for a tumor involving the head of the pancreas ( the patient did not survive the postoperative period ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1906 </Td> <Td> Development </Td> <Td> Scottish embryologist John Beard proposes that pancreatic proteolytic digestive enzymes represent the body 's main defense against cancer , and that enzyme therapy would be useful as a treatment for all types of cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1909 </Td> <Td> Development </Td> <Td> German surgeon Walter Kausch first describes the pancreaticoduodenectomy procedure . </Td> <Td> </Td> </Tr> <Tr> <Td> 1914 </Td> <Td> Achievement </Td> <Td> German surgeon Georg Hirschel performs the first successful pancreaticoduodenectomy in one stage . </Td> <Td> </Td> </Tr> <Tr> <Td> 1937 </Td> <Td> Achievement </Td> <Td> American physician Alexander Brunschwig performs the first successful pancreaticoduodenectomy in two stages for pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1940 </Td> <Td> Development </Td> <Td> American surgeon Allen Whipple performs a successful one - stage pancreaticoduodenectomy , being the first to popularize the procedure ( today also called Whipple procedure ) . His major surgical operation involves the removal of the head of the pancreas , the duodenum , the proximal jejunum , gallbladder , and often the distal stomach . This operation is performed to treat cancerous tumours of the head of the pancreas , malignant tumors involving the common bile duct , duodenal papilla or ampulla of Vater , or duodenum near the pancreas , some precancerous lesions , some cases of pancreatitis with or without a definitive cause , and rarely , severe trauma . </Td> <Td> United States </Td> </Tr> <Tr> <Td> 1942 </Td> <Td> Achievement </Td> <Td> First successful total pancreatectomy is performed at Mayo Clinic , for an insulinoma . </Td> <Td> Rochester , Minnesota , US </Td> </Tr> <Tr> <Td> 1944 </Td> <Td> Discovery </Td> <Td> First report of tuberculosis mimicking pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1947 </Td> <Td> Discovery </Td> <Td> First recognition of a causative relationship between the subcutaneous adiponecrosis and pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1951 </Td> <Td> Development </Td> <Td> First performance of resection and reconstruction of the superior mesenteric vein for pancreatic cancer at University of Minnesota . </Td> <Td> Minnesota , US </Td> </Tr> <Tr> <Td> 1955 </Td> <Td> Development </Td> <Td> Researchers first describe the clinical features of a gastrinoma ( a tumor in the pancreas or duodenum ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1958 </Td> <Td> Development </Td> <Td> Researchers first describe the persistent watery diarrhea and hypokalemia associated with a pancreatic islet - cell tumor . </Td> <Td> </Td> </Tr> <Tr> <Td> 1963 </Td> <Td> Development </Td> <Td> The first case of pancreatic cancer with skeletal metastases is described . </Td> <Td> Russia </Td> </Tr> <Tr> <Td> 1967 </Td> <Td> Discovery </Td> <Td> Study shows that more than half of patients with pancreatic cancer have psychological symptoms occurring as early as 43 months before physical symptoms . </Td> <Td> </Td> </Tr> <Tr> <Td> 1979 </Td> <Td> Discovery </Td> <Td> Researchers discover biomarker CA 19 - 9 ( commonly for diagnosis and management of patients with pancreatic cancer ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1981 </Td> <Td> Treatment </Td> <Td> Researchers discover that adding fluorouracil to standard radiation boosts one year survival from 10 percent to 40 percent for patients with locally advanced inoperable pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1981 </Td> <Td> Discovery </Td> <Td> Study at University of Maryland Medical Center links environmental exposure to pancreatic cancer . Researchers discover that male victims are more often employed in the dry - cleaning business or in occupations involving close exposure to gasoline . They also find that women at risk of PC are more likely to smoke cigarettes , have uterine tumors and have had ovaries removed or have miscarriages . </Td> <Td> Baltimore , Maryland , US </Td> </Tr> <Tr> <Td> 1985 </Td> <Td> Treatment </Td> <Td> Chemotherapy plus radiation are found to be effective as adjuvant therapy for patients with earlier stage of
<Table> <Tr> <Th> Year / period </Th> <Th> Type of event </Th> <Th> Event </Th> <Th> Location </Th> </Tr> <Tr> <Td> 1761 </Td> <Td> Development </Td> <Td> Italian anatomist Giovanni Battista Morgagni is attributed with the first known description of pancreatic cancer in his publication De Sedibus Et Causis Morborum Per Anatomen Indagatis Libri Quinque . </Td> <Td> </Td> </Tr> <Tr> <Td> 1858 </Td> <Td> Development </Td> <Td> American physician Jacob Mendez Da Costa describes the first microscopic diagnosis of adenocarcinoma , manifesting pancreatic cancer as a true disease entity . </Td> <Td> </Td> </Tr> <Tr> <Td> 1898 </Td> <Td> Development </Td> <Td> Italian surgeon Alessandro Codivilla performs the first reported attempt at a pancreaticoduodenectomy for a tumor involving the head of the pancreas ( the patient did not survive the postoperative period ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1906 </Td> <Td> Development </Td> <Td> Scottish embryologist John Beard proposes that pancreatic proteolytic digestive enzymes represent the body 's main defense against cancer , and that enzyme therapy would be useful as a treatment for all types of cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1909 </Td> <Td> Development </Td> <Td> German surgeon Walter Kausch first describes the pancreaticoduodenectomy procedure . </Td> <Td> </Td> </Tr> <Tr> <Td> 1914 </Td> <Td> Achievement </Td> <Td> German surgeon Georg Hirschel performs the first successful pancreaticoduodenectomy in one stage . </Td> <Td> </Td> </Tr> <Tr> <Td> 1937 </Td> <Td> Achievement </Td> <Td> American physician Alexander Brunschwig performs the first successful pancreaticoduodenectomy in two stages for pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1940 </Td> <Td> Development </Td> <Td> American surgeon Allen Whipple performs a successful one - stage pancreaticoduodenectomy , being the first to popularize the procedure ( today also called Whipple procedure ) . His major surgical operation involves the removal of the head of the pancreas , the duodenum , the proximal jejunum , gallbladder , and often the distal stomach . This operation is performed to treat cancerous tumours of the head of the pancreas , malignant tumors involving the common bile duct , duodenal papilla or ampulla of Vater , or duodenum near the pancreas , some precancerous lesions , some cases of pancreatitis with or without a definitive cause , and rarely , severe trauma . </Td> <Td> United States </Td> </Tr> <Tr> <Td> 1942 </Td> <Td> Achievement </Td> <Td> First successful total pancreatectomy is performed at Mayo Clinic , for an insulinoma . </Td> <Td> Rochester , Minnesota , US </Td> </Tr> <Tr> <Td> 1944 </Td> <Td> Discovery </Td> <Td> First report of tuberculosis mimicking pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1947 </Td> <Td> Discovery </Td> <Td> First recognition of a causative relationship between the subcutaneous adiponecrosis and pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1951 </Td> <Td> Development </Td> <Td> First performance of resection and reconstruction of the superior mesenteric vein for pancreatic cancer at University of Minnesota . </Td> <Td> Minnesota , US </Td> </Tr> <Tr> <Td> 1955 </Td> <Td> Development </Td> <Td> Researchers first describe the clinical features of a gastrinoma ( a tumor in the pancreas or duodenum ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1958 </Td> <Td> Development </Td> <Td> Researchers first describe the persistent watery diarrhea and hypokalemia associated with a pancreatic islet - cell tumor . </Td> <Td> </Td> </Tr> <Tr> <Td> 1963 </Td> <Td> Development </Td> <Td> The first case of pancreatic cancer with skeletal metastases is described . </Td> <Td> Russia </Td> </Tr> <Tr> <Td> 1967 </Td> <Td> Discovery </Td> <Td> Study shows that more than half of patients with pancreatic cancer have psychological symptoms occurring as early as 43 months before physical symptoms . </Td> <Td> </Td> </Tr> <Tr> <Td> 1979 </Td> <Td> Discovery </Td> <Td> Researchers discover biomarker CA 19 - 9 ( commonly for diagnosis and management of patients with pancreatic cancer ) . </Td> <Td> </Td> </Tr> <Tr> <Td> 1981 </Td> <Td> Treatment </Td> <Td> Researchers discover that adding fluorouracil to standard radiation boosts one year survival from 10 percent to 40 percent for patients with locally advanced inoperable pancreatic cancer . </Td> <Td> </Td> </Tr> <Tr> <Td> 1981 </Td> <Td> Discovery </Td> <Td> Study at University of Maryland Medical Center links environmental exposure to pancreatic cancer . Researchers discover that male victims are more often employed in the dry - cleaning business or in occupations involving close exposure to gasoline . They also find that women at risk of PC are more likely to smoke cigarettes , have uterine tumors and have had ovaries removed or have miscarriages . </Td> <Td> Baltimore , Maryland , US </Td> </Tr> <Tr> <Td> 1985 </Td> <Td> Treatment </Td> <Td> Chemotherapy plus radiation are found to be effective as adjuvant therapy for patients with earlier stage of
when was the first case of pancreatic cancer discovered
when was the first case of pancreatic cancer discovered
1761
1761