<P> Many eukaryotes have the ability to synthesize carnitine , including humans . Humans synthesize carnitine from the substrate TML ( 6 - N - trimethyllysine ) , which is in turn derived from the methylation of the amino acid lysine . TML is then hydroxylated into hydroxytrimethyllysine ( HTML ) by trimethyllysine dioxygenase , requiring the presence of ascorbic acid . HTML is then cleaved by HTML aldose , yielding 4 - trimethylaminobutyraldehyde ( TMABA ) and glycine . TMABA is then dehydrogenated into gamma - butyrobetaine , in an NAD - dependent reaction , catalyzed by TMABA dehydrogenase . Gamma - butyrobetaine is then hydroxylated by gamma butyrobetaine hydroxylase into L - carnitine , requiring iron in the form of Fe . </P>
<P> Many eukaryotes have the ability to synthesize carnitine , including humans . Humans synthesize carnitine from the substrate TML ( 6 - N - trimethyllysine ) , which is in turn derived from the methylation of the amino acid lysine . TML is then hydroxylated into hydroxytrimethyllysine ( HTML ) by trimethyllysine dioxygenase , requiring the presence of ascorbic acid . HTML is then cleaved by HTML aldose , yielding 4 - trimethylaminobutyraldehyde ( TMABA ) and glycine . TMABA is then dehydrogenated into gamma - butyrobetaine , in an NAD - dependent reaction , catalyzed by TMABA dehydrogenase . Gamma - butyrobetaine is then hydroxylated by gamma butyrobetaine hydroxylase into L - carnitine , requiring iron in the form of Fe . </P>
l carnitine what is it made out of
l carnitine what is it made out of
Gamma - butyrobetaine is then hydroxylated by gamma butyrobetaine hydroxylase into L - carnitine
Gamma - butyrobetaine is then hydroxylated by gamma butyrobetaine hydroxylase into L - carnitine