<P> Ligand binding to a receptor protein alters the chemical conformation by affecting the three - dimensional shape orientation . The conformation of a receptor protein composes the functional state . Ligands include substrates , inhibitors , activators , and neurotransmitters . The rate of binding is called affinity , and this measurement typifies a tendency or strength of the effect . Binding affinity is actualized not only by host - guest interactions , but also by solvent effects that can play a dominant , steric role which drives non-covalent binding in solution . The solvent provides a chemical environment for the ligand and receptor to adapt , and thus accept or reject each other as partners . </P>
<P> Ligand binding to a receptor protein alters the chemical conformation by affecting the three - dimensional shape orientation . The conformation of a receptor protein composes the functional state . Ligands include substrates , inhibitors , activators , and neurotransmitters . The rate of binding is called affinity , and this measurement typifies a tendency or strength of the effect . Binding affinity is actualized not only by host - guest interactions , but also by solvent effects that can play a dominant , steric role which drives non-covalent binding in solution . The solvent provides a chemical environment for the ligand and receptor to adapt , and thus accept or reject each other as partners . </P>
nature of the binding between neurotransmitter and receptor site
nature of the binding between neurotransmitter and receptor site
Ligand
Ligand