<P> In general , GABA does not cross the blood -- brain barrier , although certain areas of the brain that have no effective blood -- brain barrier , such as the periventricular nucleus , can be reached by drugs such as systemically injected GABA . At least one study suggests that orally administered GABA increases the amount of human growth hormone ( HGH ) . GABA directly injected to the brain has been reported to have both stimulatory and inhibitory effects on the production of growth hormone , depending on the physiology of the individual . Certain pro-drugs of GABA ( ex . picamilon ) have been developed to permeate the blood -- brain barrier , then separate into GABA and the carrier molecule once inside the brain . This allows for a direct increase of GABA levels throughout all areas of the brain , in a manner following the distribution pattern of the pro-drug prior to metabolism . </P>
<P> In general , GABA does not cross the blood -- brain barrier , although certain areas of the brain that have no effective blood -- brain barrier , such as the periventricular nucleus , can be reached by drugs such as systemically injected GABA . At least one study suggests that orally administered GABA increases the amount of human growth hormone ( HGH ) . GABA directly injected to the brain has been reported to have both stimulatory and inhibitory effects on the production of growth hormone , depending on the physiology of the individual . Certain pro-drugs of GABA ( ex . picamilon ) have been developed to permeate the blood -- brain barrier , then separate into GABA and the carrier molecule once inside the brain . This allows for a direct increase of GABA levels throughout all areas of the brain , in a manner following the distribution pattern of the pro-drug prior to metabolism . </P>
a type of drug that works by enhancing the action of the neurotransmitter gaba
a type of drug that works by enhancing the action of the neurotransmitter gaba
picamilon
picamilon