<P> U.S. Route 50 ( US 50 ) is a major east -- west route of the U.S. Highway system , stretching just over 3,000 miles ( 4,800 km ) from West Sacramento , California , to Ocean City , Maryland , on the Atlantic Ocean . Until 1972 , when it was replaced by Interstate Highways west of the Sacramento area , it extended ( by way of Stockton , the Altamont Pass , and the Bay Bridge ) to San Francisco , near the Pacific Ocean . The Interstates were constructed later and are mostly separate from this route . It generally serves a corridor south of Interstates 70 and 80 and north of Interstates 64 and 40 . The route runs through mostly rural desert and mountains in the Western United States , with the section through Nevada known as `` The Loneliest Road in America '' . In the Midwest , US 50 continues through mostly rural areas of farms as well as a few large cities including Kansas City , Missouri ; St. Louis , Missouri ; and Cincinnati , Ohio . The route continues into the Eastern United States , where it passes through the Appalachian Mountains in West Virginia before heading through Washington , D.C. From there , US 50 continues through Maryland as a high - speed road to Ocean City . Signs at each end give the length as 3,073 miles ( 4,946 km ) , but the actual distance is slightly less , due to realignments since the former figure was measured . US 50 passes through a total of 12 states ; California , Nevada , Utah , Colorado , Kansas , Missouri , Illinois , Indiana , Ohio , West Virginia , Virginia , and Maryland , as well as the District of Columbia . </P>
<P> U.S. Route 50 ( US 50 ) is a major east -- west route of the U.S. Highway system , stretching just over 3,000 miles ( 4,800 km ) from West Sacramento , California , to Ocean City , Maryland , on the Atlantic Ocean . Until 1972 , when it was replaced by Interstate Highways west of the Sacramento area , it extended ( by way of Stockton , the Altamont Pass , and the Bay Bridge ) to San Francisco , near the Pacific Ocean . The Interstates were constructed later and are mostly separate from this route . It generally serves a corridor south of Interstates 70 and 80 and north of Interstates 64 and 40 . The route runs through mostly rural desert and mountains in the Western United States , with the section through Nevada known as `` The Loneliest Road in America '' . In the Midwest , US 50 continues through mostly rural areas of farms as well as a few large cities including Kansas City , Missouri ; St. Louis , Missouri ; and Cincinnati , Ohio . The route continues into the Eastern United States , where it passes through the Appalachian Mountains in West Virginia before heading through Washington , D.C. From there , US 50 continues through Maryland as a high - speed road to Ocean City . Signs at each end give the length as 3,073 miles ( 4,946 km ) , but the actual distance is slightly less , due to realignments since the former figure was measured . US 50 passes through a total of 12 states ; California , Nevada , Utah , Colorado , Kansas , Missouri , Illinois , Indiana , Ohio , West Virginia , Virginia , and Maryland , as well as the District of Columbia . </P>
where does us highway 50 start and end
where does us highway 50 start and end
from West Sacramento , California , to Ocean City , Maryland ,
from West Sacramento , California , to Ocean City , Maryland ,