<P> Phase - contrast microscopy is particularly important in biology . It reveals many cellular structures that are not visible with a simpler bright - field microscope , as exemplified in the figure . These structures were made visible to earlier microscopists by staining , but this required additional preparation and killed the cells . The phase - contrast microscope made it possible for biologists to study living cells and how they proliferate through cell division . After its invention in the early 1930s , phase - contrast microscopy proved to be such an advancement in microscopy that its inventor Frits Zernike was awarded the Nobel Prize in Physics in 1953 . </P>
<P> Phase - contrast microscopy is particularly important in biology . It reveals many cellular structures that are not visible with a simpler bright - field microscope , as exemplified in the figure . These structures were made visible to earlier microscopists by staining , but this required additional preparation and killed the cells . The phase - contrast microscope made it possible for biologists to study living cells and how they proliferate through cell division . After its invention in the early 1930s , phase - contrast microscopy proved to be such an advancement in microscopy that its inventor Frits Zernike was awarded the Nobel Prize in Physics in 1953 . </P>
where would phase contrast microscopy improve image quality
where would phase contrast microscopy improve image quality
cellular structures
cellular structures