<P> AMH is activated by SOX9 in the Sertoli cells of the male fetus . Its expression inhibits the development of the female reproductive tract , or Müllerian ducts ( paramesonephric ducts ) , in the male embryo , thereby arresting the development of fallopian tubes , uterus , and upper vagina . AMH expression is critical to sex differentiation at a specific time during fetal development , and appears to be tightly regulated by nuclear receptor SF - 1 , transcription GATA factors , sex - reversal gene DAX1 , and follicle - stimulating hormone ( FSH ) . Mutations in both the AMH gene and the type II AMH receptor have been shown to cause the persistence of Müllerian derivatives in males that are otherwise normally masculinized . </P>
<P> AMH is activated by SOX9 in the Sertoli cells of the male fetus . Its expression inhibits the development of the female reproductive tract , or Müllerian ducts ( paramesonephric ducts ) , in the male embryo , thereby arresting the development of fallopian tubes , uterus , and upper vagina . AMH expression is critical to sex differentiation at a specific time during fetal development , and appears to be tightly regulated by nuclear receptor SF - 1 , transcription GATA factors , sex - reversal gene DAX1 , and follicle - stimulating hormone ( FSH ) . Mutations in both the AMH gene and the type II AMH receptor have been shown to cause the persistence of Müllerian derivatives in males that are otherwise normally masculinized . </P>
when the testis does not produce anti-müllerian hormone the müllerian ducts develop into
when the testis does not produce anti-müllerian hormone the müllerian ducts develop into
the development of the female reproductive tract
the development of the female reproductive tract