<P> The nucleolus ( / nj uː ˈkliːələs , - kliˈoʊləs / , plural nucleoli / - laɪ / ) is the largest structure in the nucleus of eukaryotic cells . It is best known as the site of ribosome biogenesis . Nucleoli also participate in the formation of signal recognition particles and play a role in the cell 's response to stress . Nucleoli are made of proteins , DNA and RNA and form around specific chromosomal regions called nucleolar organizing regions . Malfunction of nucleoli can be the cause of several human conditions called `` nucleolopathies '' and the nucleolus is being investigated as a target for cancer chemotherapy . </P>
<P> The nucleolus ( / nj uː ˈkliːələs , - kliˈoʊləs / , plural nucleoli / - laɪ / ) is the largest structure in the nucleus of eukaryotic cells . It is best known as the site of ribosome biogenesis . Nucleoli also participate in the formation of signal recognition particles and play a role in the cell 's response to stress . Nucleoli are made of proteins , DNA and RNA and form around specific chromosomal regions called nucleolar organizing regions . Malfunction of nucleoli can be the cause of several human conditions called `` nucleolopathies '' and the nucleolus is being investigated as a target for cancer chemotherapy . </P>
the nucleoli found within the nucleus are the sites of -- -- -- -- synthesis . ​
the nucleoli found within the nucleus are the sites of -- -- -- -- synthesis . ​
ribosome
ribosome