<P> For a cell to divide , it must first replicate its DNA . This process is initiated at particular points in the DNA , known as `` origins '' , which are targeted by initiator proteins . In E. coli this protein is DnaA ; in yeast , this is the origin recognition complex . Sequences used by initiator proteins tend to be `` AT - rich '' ( rich in adenine and thymine bases ) , because A-T base pairs have two hydrogen bonds ( rather than the three formed in a C-G pair ) and thus are easier to strand - separate . Once the origin has been located , these initiators recruit other proteins and form the pre-replication complex , which unwinds the double - stranded DNA . </P>
<P> For a cell to divide , it must first replicate its DNA . This process is initiated at particular points in the DNA , known as `` origins '' , which are targeted by initiator proteins . In E. coli this protein is DnaA ; in yeast , this is the origin recognition complex . Sequences used by initiator proteins tend to be `` AT - rich '' ( rich in adenine and thymine bases ) , because A-T base pairs have two hydrogen bonds ( rather than the three formed in a C-G pair ) and thus are easier to strand - separate . Once the origin has been located , these initiators recruit other proteins and form the pre-replication complex , which unwinds the double - stranded DNA . </P>
where does the process of dna replication begin
where does the process of dna replication begin
`` origins ''
`` origins ''