person A: One the way to work_comma_ I got a flat tire and I missed a very important presentation.  I was pretty upset.
person B: Oh_comma_ man!  That is a nightmare!  Was your boss upset with you?
person A: No_comma_ he understood_comma_ but I missed a really good presentation.  I was not happy.
person B: Yeah_comma_ it happens to the best of us.  You just have to try and forget about it and move forward.