def test_set_obsm(adata):
    init_hash = joblib.hash(adata)

    dim0_size = np.random.randint(2, adata.shape[0] - 1)
    dim1_size = np.random.randint(1, 99)
    orig_obsm_val = adata.obsm["o"].copy()
    subset_idx = np.random.choice(adata.obs_names, dim0_size, replace=False)

    subset = adata[subset_idx, :]
    assert subset.is_view
    subset.obsm = dict(o=np.ones((dim0_size, dim1_size)))
    assert not subset.is_view
    assert np.all(orig_obsm_val == adata.obsm["o"])  # Checking for mutation
    assert np.all(subset.obsm["o"] == np.ones((dim0_size, dim1_size)))

    subset = adata[subset_idx, :]
    subset_hash = joblib.hash(subset)
    with pytest.raises(ValueError):
        subset.obsm = dict(o=np.ones((dim0_size + 1, dim1_size)))
    with pytest.raises(ValueError):
        subset.varm = dict(o=np.ones((dim0_size - 1, dim1_size)))
    assert subset_hash == joblib.hash(subset)

    # Only modification have been made to a view
    assert init_hash == joblib.hash(adata)
def compute_svm_score_nestedCV(K, y, n_folds,
                               scoring=balanced_accuracy_scoring,
                               random_state=None,
                               param_grid=[{'C': np.logspace(-5, 5, 25)}]):
    """Compute cross-validated score of SVM using precomputed kernel.
    """
    cv = StratifiedKFold(y, n_folds=n_folds, shuffle=True,
                         random_state=random_state)
    scores = np.zeros(n_folds)
    for i, (train, test) in enumerate(cv):
        cvclf = SVC(kernel='precomputed')
        y_train = y[train]
        cvcv = StratifiedKFold(y_train, n_folds=n_folds,
                               shuffle=True,
                               random_state=random_state)
        clf = GridSearchCV(cvclf, param_grid=param_grid, scoring=scoring,
                           cv=cvcv, n_jobs=1)
        clf.fit(K[train, :][:, train], y_train)
        # print clf.best_params_
        scores[i] = clf.score(K[test, :][:, train], y[test])

    return scores.mean()