def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def test_impl(n):
            df = pd.DataFrame({'A': np.arange(n) + 1.0, 'B': np.random.ranf(n)})
            Ac = df.A.pct_change(1)
            return Ac.sum()