def test_drop_obs_column():
    adata = ad.AnnData(np.array(X_list), obs=obs_dict, dtype="int32")

    subset = adata[:2]
    assert subset.is_view
    # returns a copy of obs
    assert subset.obs.drop(columns=["oanno1"]).columns.tolist() == ["oanno2", "oanno3"]
    assert subset.is_view
    # would modify obs, so it should actualize subset and not modify adata
    subset.obs.drop(columns=["oanno1"], inplace=True)
    assert not subset.is_view
    assert subset.obs.columns.tolist() == ["oanno2", "oanno3"]

    assert adata.obs.columns.tolist() == ["oanno1", "oanno2", "oanno3"]
def flush_to_index(self) -> None:
        """Flush changes in our configuration file to the index"""
        assert self._smref is not None
        # should always have a file here
        assert not isinstance(self._file_or_files, BytesIO)

        sm = self._smref()
        if sm is not None:
            index = self._index
            if index is None:
                index = sm.repo.index
            # END handle index
            index.add([sm.k_modules_file], write=self._auto_write)
            sm._clear_cache()
        # END handle weakref