def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def __update_mean(self, rc, mc):
        mean = 0.0
        for index_point in range(len(self.__data)):
            mean += rc[index_point] * self.__data[index_point]