def test_double_index(subset_func, subset_func2):
    adata = gen_adata((10, 10))
    obs_subset = subset_func(adata.obs_names)
    var_subset = subset_func2(adata.var_names)
    v1 = adata[obs_subset, var_subset]
    v2 = adata[obs_subset, :][:, var_subset]

    assert np.all(asarray(v1.X) == asarray(v2.X))
    assert np.all(v1.obs == v2.obs)
    assert np.all(v1.var == v2.var)
def compute_rbf_kernel_matrix(X):
    """Compute the RBF kernel matrix with sigma2 as the median pairwise
    distance.
    """
    sigma2 = np.median(pairwise_distances(X, metric='euclidean'))**2
    K = pairwise_kernels(X, X, metric='rbf', gamma=1.0/sigma2, n_jobs=-1)
    return K