def test_not_set_subset_X(matrix_type, subset_func):
    adata = ad.AnnData(matrix_type(asarray(sparse.random(20, 20))))
    init_hash = joblib.hash(adata)
    orig_X_val = adata.X.copy()
    while True:
        subset_idx = slice_subset(adata.obs_names)
        if len(adata[subset_idx, :]) > 2:
            break
    subset = adata[subset_idx, :]

    subset = adata[:, subset_idx]

    internal_idx = _normalize_index(
        subset_func(np.arange(subset.X.shape[1])), subset.var_names
    )
    assert subset.is_view
    subset.X[:, internal_idx] = 1
    assert not subset.is_view
    assert not np.any(asarray(adata.X != orig_X_val))

    assert init_hash == joblib.hash(adata)
def from_envvar(self, variable_name: str, silent: bool = False) -> bool:
        """Loads a configuration from an environment variable pointing to
        a configuration file.  This is basically just a shortcut with nicer
        error messages for this line of code::

            app.config.from_pyfile(os.environ['YOURAPPLICATION_SETTINGS'])

        :param variable_name: name of the environment variable
        :param silent: set to ``True`` if you want silent failure for missing
                       files.
        :return: bool. ``True`` if able to load config, ``False`` otherwise.
        """
        rv = os.environ.get(variable_name)
        if not rv:
            if silent:
                return False
            raise RuntimeError(
                f"The environment variable {variable_name!r} is not set"
                " and as such configuration could not be loaded. Set"
                " this variable and make it point to a configuration"
                " file"
            )
        return self.from_pyfile(rv, silent=silent)