def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def __new__(cls, *args, **kwargs):
        raise TypeError("Instances of {} are not allowed to be constructed!".format(cls.__name__))