def test_modify_uns_in_copy():
    # https://github.com/theislab/anndata/issues/571
    adata = ad.AnnData(np.ones((5, 5)), uns={"parent": {"key": "value"}})
    adata_copy = adata[:3].copy()
    adata_copy.uns["parent"]["key"] = "new_value"
    assert adata.uns["parent"]["key"] != adata_copy.uns["parent"]["key"]
def _prepare_streams(self) -> None:
        if self._write_stream is not None:
            return
        if self.filename:
            filepath = os.path.join(self.dirpath, self._prepare_filename())
            fs = get_filesystem(filepath)
            file = fs.open(filepath, "a")
            self._output_file = file
            self._write_stream = file.write
        else:
            self._write_stream = self._rank_zero_info