def test_view_of_view_modification():
    adata = ad.AnnData(np.zeros((10, 10)))
    adata[0, :][:, 5:].X = np.ones(5)
    assert np.all(adata.X[0, 5:] == np.ones(5))
    adata[[1, 2], :][:, [1, 2]].X = np.ones((2, 2))
    assert np.all(adata.X[1:3, 1:3] == np.ones((2, 2)))

    adata.X = sparse.csr_matrix(adata.X)
    adata[0, :][:, 5:].X = np.ones(5) * 2
    assert np.all(asarray(adata.X)[0, 5:] == np.ones(5) * 2)
    adata[[1, 2], :][:, [1, 2]].X = np.ones((2, 2)) * 2
    assert np.all(asarray(adata.X)[1:3, 1:3] == np.ones((2, 2)) * 2)
def add_handles(self, model, forward_handle, backward_handle):
        """
        Add handles to all non-container layers in the model.
        Recursively for non-container layers
        """
        handles_list = []
        model_children = list(model.children())
        if model_children:
            for child in model_children:
                handles_list.extend(self.add_handles(child, forward_handle, backward_handle))
        else:  # leaves
            handles_list.append(model.register_forward_hook(forward_handle))
            handles_list.append(model.register_backward_hook(backward_handle))
        return handles_list