def test_double_index(subset_func, subset_func2):
    adata = gen_adata((10, 10))
    obs_subset = subset_func(adata.obs_names)
    var_subset = subset_func2(adata.var_names)
    v1 = adata[obs_subset, var_subset]
    v2 = adata[obs_subset, :][:, var_subset]

    assert np.all(asarray(v1.X) == asarray(v2.X))
    assert np.all(v1.obs == v2.obs)
    assert np.all(v1.var == v2.var)
def md5(fname):
    hash_md5 = hashlib.md5()
    with open(fname, "rb") as f:
        for chunk in iter(lambda: f.read(4096), b""):
            hash_md5.update(chunk)
    return hash_md5.hexdigest()