def test_view_of_view_modification():
    adata = ad.AnnData(np.zeros((10, 10)))
    adata[0, :][:, 5:].X = np.ones(5)
    assert np.all(adata.X[0, 5:] == np.ones(5))
    adata[[1, 2], :][:, [1, 2]].X = np.ones((2, 2))
    assert np.all(adata.X[1:3, 1:3] == np.ones((2, 2)))

    adata.X = sparse.csr_matrix(adata.X)
    adata[0, :][:, 5:].X = np.ones(5) * 2
    assert np.all(asarray(adata.X)[0, 5:] == np.ones(5) * 2)
    adata[[1, 2], :][:, [1, 2]].X = np.ones((2, 2)) * 2
    assert np.all(asarray(adata.X)[1:3, 1:3] == np.ones((2, 2)) * 2)
def flush_to_index(self) -> None:
        """Flush changes in our configuration file to the index"""
        assert self._smref is not None
        # should always have a file here
        assert not isinstance(self._file_or_files, BytesIO)

        sm = self._smref()
        if sm is not None:
            index = self._index
            if index is None:
                index = sm.repo.index
            # END handle index
            index.add([sm.k_modules_file], write=self._auto_write)
            sm._clear_cache()
        # END handle weakref