def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def remove_item(self, item):
    if (self._locker.is_unlocked("prevent_removal_below_min_size")
        and len(self._items) == self._min_size):
      return