def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def __calculate_initial_clusters(self, centers):
        """!
        @brief Calculate Euclidean distance to each point from the each cluster. 
        @brief Nearest points are captured by according clusters and as a result clusters are updated.