def adata():
    adata = ad.AnnData(np.zeros((100, 100)))
    adata.obsm["o"] = np.zeros((100, 50))
    adata.varm["o"] = np.zeros((100, 50))
    return adata
def update_on():
  global _updating
  if not '_updating' in globals(): _updating = False
  if _updating: return