My initial google searches say XFS or ReiserFS, but what does the community have to say about this? What are your experiences with 50TB sizes and up? Edit: After inquiring on IRC I think I would recommend Ext4, and splitting up the storage into 10TB chunks. But I'd still be very interested to hear experiences. 
What is the recommended filesystem to use when reaching sizes of 50TB?
linux;filesystems
Imho, its a bad idea to split the 50TB file system into smaller chunks because it introduces problems at a later time: either the partitions are too small, or you have to use something like LVM to be able to resize your partitions later. Note that resizing/shrinking is not supported on all filesystems.For the fs choice, i would go with ext4.