Mapping co-ancestry connections between the genome of a Medieval individual and modern Europeans
Manuel Ferrando-Bernal|Carlos Morcillo-Suárez|Toni de-Dios|Pere Gelabert|Sergi Civit|Antònia Díaz-Carvajal|Imma Ollich-Castanyer|Morten E. Allentoft|Sergi Valverde|Carles Lalueza‐Fox
Abstract Historical genetic links among similar populations can be difficult to establish. Identity by descent (IBD) analyses find genomic blocks that represent direct genealogical relationships individuals. However, this method has rarely been applied ancient genomes because IBD stretches are progressively fragmented recombination and thus not recognizable after few tens of generations. To explore such relationships, we estimated long modern Europeans, generating networks uncover the structures. We found Basques, Sardinians, Icelanders Orcadians form, each them, highly intraconnected sub-clusters in a European network, indicating dense within small, isolated populations. also exposed individual -such as connection between one Basque Icelandic individual- cannot uncovered with other, widely used population genetics methods PCA or ADMIXTURE. Moreover, using DNA technology sequenced Late Medieval (Barcelona, Spain) high coverage identified shared her Europeans. The statistically overrepresented only Spaniards, which is geographically closest population. This approach produce fine-scale reflection ancestry across different world, offering link from past present.
Scientific Reports|Europe PMC (PubMed Central)|Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)|Research at the University of Copenhagen (University of Copenhagen)|Repositori digital de la UPF (Universitat Pompeu Fabra)|DIGITAL.CSIC (Spanish National Research Council (CSIC))|PubMed Central