Michael P Castro Bradford P Whitcomb Deborah A Zajchowski Robert L Coleman
10.1186/s40661-015-0013-2
Gynecol Oncol Res Pract
2015 Aug 28;2:4.
clear cell carcinoma genomic kras mutation metformin molecular profiling next generation sequencing ovarian cancer pik3ca mutation personalized medicine precision medicine targeted therapy trametinib
CC BY
https://pubmed.ncbi.nlm.nih.gov/27231564/
Case Reports
PMC4880882
27231564
Successful use of next generation genomic sequencing (NGS)-directed therapy of clear cell carcinoma of the ovary (CCCO) with trametinib and metformin in a patient with chemotherapy-refractory disease
2015