Christoph B Geier Kai M T Sauerwein Alexander Leiss-Piller Isabella Zmek Michael B Fischer Martha M Eibl Hermann M Wolf
10.3389/fimmu.2018.02984
Front Immunol
2018 Dec 18;9:2984.
b-cell defects blnk btk marginal-zone b cells natural antibodies primary immunodeficiency selective igm deficiency
CC BY
https://pubmed.ncbi.nlm.nih.gov/30619340/
Adaptor Proteins, Signal Transducing / genetics Agammaglobulinaemia Tyrosine Kinase / genetics Agammaglobulinemia / genetics B-Lymphocytes / immunology Immunoglobulin M / deficiency
Adaptor Proteins, Signal Transducing / genetics Agammaglobulinaemia Tyrosine Kinase / genetics Agammaglobulinemia / genetics B-Lymphocytes / immunology Immunoglobulin M / deficiency Case Reports Adaptor Proteins, Signal Transducing / metabolism Adolescent Adult Agammaglobulinaemia Tyrosine Kinase / metabolism Agammaglobulinemia / immunology B-Lymphocytes / metabolism Humans Immunoglobulin M / immunology Male Receptors, Antigen, B-Cell / immunology Receptors, Antigen, B-Cell / metabolism Signal Transduction / genetics Signal Transduction / immunology Adaptor Proteins, Signal Transducing B cell linker protein Immunoglobulin M Receptors, Antigen, B-Cell Agammaglobulinaemia Tyrosine Kinase BTK protein, human
PMC6305442
30619340
Hypomorphic Mutations in the BCR Signalosome Lead to Selective Immunoglobulin M Deficiency and Impaired B-cell Homeostasis
2018