Jamie A Lopez Tahereh Noori Adrian Minson Lu Li Jovanoska Kevin Thia Michael S Hildebrand Hedieh Akhlaghi Phillip K Darcy Michael H Kershaw Natasha J Brown Andrew Grigg Joseph A Trapani Ilia Voskoboinik
10.3389/fimmu.2018.00529
Front Immunol
2018 Mar 15;9:529.
munc18-1 munc18-2 apoptosis cytotoxic t cells cytotoxic lymphocytes familial haemophagocytic lymphohistiocytosis immunodeficiency natural killer cells
CC BY
https://pubmed.ncbi.nlm.nih.gov/29599780/
Munc18 Proteins / genetics Munc18 Proteins / immunology T-Lymphocytes, Cytotoxic / immunology
Munc18 Proteins / genetics Munc18 Proteins / immunology T-Lymphocytes, Cytotoxic / immunology Case Reports Research Support, Non-U.S. Gov't Alleles Cell Line Cytotoxicity, Immunologic Female Humans Killer Cells, Natural / immunology Leukocytes, Mononuclear / immunology Middle Aged Mutation Munc18 Proteins STXBP1 protein, human STXBP2 protein, human
PMC5862791
29599780
Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing
2018