Shuier Zheng Fenglin Wang Jin Huang Yan Zhou Quanjun Yang Guowei Qian Chenliang Zhou Daliu Min Lele Song Zan Shen
10.3389/fendo.2021.625226
Front Endocrinol (Lausanne)
2021 Jun 18;12:625226.
chemotherapy immunotherapy osteosarcoma sequencing tumor mutational burden whole-exome sequencing
CC BY
https://pubmed.ncbi.nlm.nih.gov/34220700/
Antibodies, Monoclonal, Humanized / therapeutic use Bone Neoplasms / drug therapy Mutation Osteosarcoma / drug therapy Ribs / pathology
Antibodies, Monoclonal, Humanized / therapeutic use Bone Neoplasms / drug therapy Mutation Osteosarcoma / drug therapy Ribs / pathology Case Reports Research Support, Non-U.S. Gov't Adult Antineoplastic Combined Chemotherapy Protocols / therapeutic use Bone Neoplasms / genetics Bone Neoplasms / pathology DNA Copy Number Variations Exome Sequencing Female Humans Osteosarcoma / genetics Osteosarcoma / pathology Remission Induction Treatment Outcome Antibodies, Monoclonal, Humanized pembrolizumab
PMC8249865
34220700
Case Report: Sequential Chemotherapy and Immunotherapy Produce Sustained Response in Osteosarcoma With High Tumor Mutational Burden
2021