Qun Zhang Jing Hu Yaping Zhang Li Li Ting Wang Xiaoping Qian
10.3389/fimmu.2022.953421
Front Immunol
2022 Aug 5;13:953421.
anti-pd1 therapy colorectal cancer lynch syndrome microsatellite instability-high resistance
CC BY
https://pubmed.ncbi.nlm.nih.gov/35990637/
Colorectal Neoplasms, Hereditary Nonpolyposis / drug therapy Colorectal Neoplasms, Hereditary Nonpolyposis / genetics Microsatellite Instability
Colorectal Neoplasms, Hereditary Nonpolyposis / drug therapy Colorectal Neoplasms, Hereditary Nonpolyposis / genetics Microsatellite Instability Case Reports Research Support, Non-U.S. Gov't Germ-Line Mutation Humans Immunotherapy MutS Homolog 2 Protein / genetics MSH2 protein, human MutS Homolog 2 Protein
PMC9389357
35990637
Case report: A colorectal cancer patient with microsatellite instability-high and MSH2 germline mutation failed to respond to anti-PD-1 immunotherapy
2022