Rebecca Pavlos Simon Mallal David Ostrov Yuri Pompeu Elizabeth Phillips
10.1016/j.jaip.2013.11.005
J Allergy Clin Immunol Pract
2014 Jan-Feb;2(1):21-33.
abc adr agep abacavir acute generalized exanthematous pustulosis adverse drug reaction cbz cmv ctl carbamazepine cytomegalovirus cytotoxic lymphocyte dihs dress dress-dihs-hss drug reaction with eosinophilia and systemic symptoms drug-induced hypersensitivity syndrome ebv epstein-barr virus hhv hla hsr hss human herpesvirus human leukocyte antigen hypersensitivity reaction hypersensitivity syndrome inf-γ interferon gamma nsaid nonsteroidal anti-inflammatory drug orally pbmc peripheral blood mononuclear cell scar sjs sjs-ten severe cutaneous adverse drug reaction steven-johnson syndrome t-cell receptor tcr ten toxic epidermal necrolysis twice a day viral reactivation bid po
author_manuscript
https://pubmed.ncbi.nlm.nih.gov/24565765/
Anticonvulsants / adverse effects Carbamazepine / adverse effects Drug Hypersensitivity Syndrome / etiology Exanthema / etiology Fever / etiology HLA Antigens / immunology Stevens-Johnson Syndrome / etiology Virus Activation Viruses / immunology
Anticonvulsants / adverse effects Carbamazepine / adverse effects Drug Hypersensitivity Syndrome / etiology Exanthema / etiology Fever / etiology HLA Antigens / immunology Stevens-Johnson Syndrome / etiology Virus Activation Viruses / immunology Case Reports Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Video-Audio Media Adult Cytomegalovirus / immunology Cytomegalovirus / pathogenicity Dideoxynucleosides / adverse effects Drug Hypersensitivity Syndrome / diagnosis Drug Hypersensitivity Syndrome / immunology Drug Hypersensitivity Syndrome / therapy Drug Hypersensitivity Syndrome / virology Exanthema / diagnosis Exanthema / immunology Exanthema / therapy Exanthema / virology Female Fever / diagnosis Fever / immunology Fever / therapy Fever / virology HIV-1 / immunology HIV-1 / pathogenicity HLA Antigens / genetics Herpesvirus 2, Human / immunology Herpesvirus 2, Human / pathogenicity Herpesvirus 3, Human / immunology Herpesvirus 3, Human / pathogenicity Humans Prognosis Reverse Transcriptase Inhibitors / adverse effects Risk Factors Severity of Illness Index Skin Tests Stevens-Johnson Syndrome / diagnosis Stevens-Johnson Syndrome / immunology Stevens-Johnson Syndrome / therapy Stevens-Johnson Syndrome / virology Viruses / pathogenicity Anticonvulsants Dideoxynucleosides HLA Antigens Reverse Transcriptase Inhibitors Carbamazepine abacavir
PMC4020624
24565765
Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy
2014