Leidy C Merselis Shirley Y Jiang Stanley F Nelson Hane Lee Kavitha K Prabaker Jennifer L Baker George P Munson Manish J Butte
10.3389/fimmu.2020.601584
Front Immunol
2020 Nov 3;11:601584.
mpeg1 ptyr430* case report interferon gamma membrane attack complex perforin-2 primary immunodeficiency
CC BY
https://pubmed.ncbi.nlm.nih.gov/33224153/
Candidiasis, Cutaneous / genetics Coinfection / genetics Haploinsufficiency Immunity, Innate / genetics Membrane Proteins / genetics Phagocytes / immunology Pore Forming Cytotoxic Proteins / genetics Skin Diseases, Bacterial / genetics
Candidiasis, Cutaneous / genetics Coinfection / genetics Haploinsufficiency Immunity, Innate / genetics Membrane Proteins / genetics Phagocytes / immunology Pore Forming Cytotoxic Proteins / genetics Skin Diseases, Bacterial / genetics Case Reports Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Candidiasis, Cutaneous / drug therapy Candidiasis, Cutaneous / immunology Candidiasis, Cutaneous / microbiology Coinfection / drug therapy Coinfection / immunology Coinfection / microbiology Female Genetic Predisposition to Disease Humans Immunity, Innate / drug effects Interferon-gamma / therapeutic use Phagocytes / drug effects Phagocytes / microbiology Phenotype Skin Diseases, Bacterial / drug therapy Skin Diseases, Bacterial / immunology Skin Diseases, Bacterial / microbiology Treatment Outcome Young Adult MPEG1 protein, human Membrane Proteins Pore Forming Cytotoxic Proteins perforin 2 Interferon-gamma
PMC7670069
33224153
MPEG1/Perforin-2 Haploinsufficiency Associated Polymicrobial Skin Infections and Considerations for Interferon-γ Therapy
2020