Paola Maura Tricarico Rossella Gratton Carlos André Dos Santos-Silva Ronald Rodrigues de Moura Blendi Ura Eduardo Sommella Pietro Campiglia Cecilia Del Vecchio Chiara Moltrasio Irene Berti Adamo Pio D'Adamo Ahmed M A Elsherbini Lena Staudenmaier Karin Chersi Michele Boniotto Bernhard Krismer Birgit Schittek Sergio Crovella
10.3389/fimmu.2022.1060547
Front Immunol
2022 Dec 5;13:1060547.
antimicrobial peptides bacteria dermcidin genetics hidradenitis suppurativa
CC BY
https://pubmed.ncbi.nlm.nih.gov/36544771/
Anti-Infective Agents / metabolism Dermcidins Hidradenitis Suppurativa / genetics Hidradenitis Suppurativa / metabolism
Anti-Infective Agents / metabolism Dermcidins Hidradenitis Suppurativa / genetics Hidradenitis Suppurativa / metabolism Case Reports Research Support, Non-U.S. Gov't Child Female Humans Male Mutation Peptides / genetics Peptides / metabolism Skin / metabolism Anti-Infective Agents Dermcidins Peptides
PMC9760663
36544771
A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
2022