Yong Zhang Jia-Jia Yuan Hong-Li Liu Zhen Tian Si-Wei Liu Bin Li
10.2174/1566523219666190618094505
Curr Gene Ther
2019;19(2):134-138.
leber's hereditary optic neuropathy dormant gene therapy retinal ganglion cells time window visual acuity
CC BY-NC
https://pubmed.ncbi.nlm.nih.gov/31237206/
DNA, Mitochondrial / genetics Genetic Therapy Optic Atrophy, Hereditary, Leber / therapy Visual Acuity / genetics
DNA, Mitochondrial / genetics Genetic Therapy Optic Atrophy, Hereditary, Leber / therapy Visual Acuity / genetics Case Reports Research Support, Non-U.S. Gov't Adolescent Adult Evoked Potentials, Visual / genetics Evoked Potentials, Visual / physiology Female Humans Male Mutation / genetics Optic Atrophy, Hereditary, Leber / genetics Optic Atrophy, Hereditary, Leber / physiopathology Retinal Ganglion Cells / metabolism Retinal Ganglion Cells / pathology Visual Fields / genetics Young Adult DNA, Mitochondrial
PMC6806533
31237206
Three Cases of Leber's Hereditary Optic Neuropathy with Rapid Increase in Visual Acuity After Gene Therapy
2019