J Aidan Carney Charalampos Lyssikatos Maya B Lodish Constantine A Stratakis
10.1016/j.humpath.2014.09.005
Hum Pathol
2015 Jan;46(1):40-9.
adrenal cortical nodules cushing syndrome genetics prkaca
author_manuscript
https://pubmed.ncbi.nlm.nih.gov/25449630/
Adrenal Cortex / pathology Cushing Syndrome / genetics Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / genetics DNA Copy Number Variations Gene Amplification Gene Dosage
Adrenal Cortex / pathology Cushing Syndrome / genetics Cyclic AMP-Dependent Protein Kinase Catalytic Subunits / genetics DNA Copy Number Variations Gene Amplification Gene Dosage Case Reports Research Support, N.I.H., Intramural Adrenal Cortex / chemistry Adrenal Cortex / diagnostic imaging Adrenal Cortex / surgery Adrenalectomy Adult Atrophy Biomarkers / analysis Biopsy Child Child, Preschool Cushing Syndrome / diagnostic imaging Cushing Syndrome / enzymology Cushing Syndrome / pathology Cushing Syndrome / surgery Female Genetic Predisposition to Disease Humans Hyperplasia Immunohistochemistry Inhibins / analysis Ki-67 Antigen / analysis Magnetic Resonance Imaging Male Phenotype Synaptophysin / analysis Time Factors Tomography, X-Ray Computed Treatment Outcome Vimentin / analysis Young Adult Biomarkers Ki-67 Antigen SYP protein, human Synaptophysin Vimentin inhibin A Inhibins Cyclic AMP-Dependent Protein Kinase Catalytic Subunits PRKACA protein, human
PMC6309372
25449630
Germline PRKACA amplification leads to Cushing syndrome caused by 3 adrenocortical pathologic phenotypes
2015