Masahiro Hiratsuka Hiroshi Yamashita Fumika Akai Hiroki Hosono Eiji Hishinuma Noriyasu Hirasawa Takahiro Mori
10.1371/journal.pone.0124818
PLoS One
2015 Apr 27;10(4):e0124818.
CC BY
https://pubmed.ncbi.nlm.nih.gov/25915935/
Amidohydrolases / genetics Antineoplastic Agents / adverse effects Asian People / genetics Capecitabine / adverse effects Colonic Neoplasms / drug therapy Polymorphism, Single Nucleotide
Amidohydrolases / genetics Antineoplastic Agents / adverse effects Asian People / genetics Capecitabine / adverse effects Colonic Neoplasms / drug therapy Polymorphism, Single Nucleotide Case Reports Research Support, Non-U.S. Gov't Adult Aged Amidohydrolases / deficiency Antineoplastic Agents / administration & dosage Capecitabine / administration & dosage Codon, Nonsense Colonic Neoplasms / genetics Colonic Neoplasms / surgery Colonic Neoplasms / urine Female Humans Japan Male Middle Aged Mutation, Missense Pedigree Uracil / urine Antineoplastic Agents Codon, Nonsense Uracil Capecitabine Amidohydrolases dihydropyrimidinase
PMC4411063
25915935
Genetic polymorphisms of dihydropyrimidinase in a Japanese patient with capecitabine-induced toxicity
2015