Yao Sun Yongfeng Su Yizhi Wang Na Liu Yuhang Li Jianlin Chen Zhuoqing Qiao Jingwen Niu Jiangwei Hu Bin Zhang Hongmei Ning Liangding Hu
10.3389/fimmu.2021.728962
Front Immunol
2021 Oct 7;12:728962.
b-all cd19 cd22 il-15 chimeric antigen receptor-t cells extramedullary relapse
CC BY
https://pubmed.ncbi.nlm.nih.gov/34691036/
Antigens, CD19 / genetics Genetic Therapy Immunotherapy, Adoptive Interleukin-15 / genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy Receptors, Chimeric Antigen / genetics Sialic Acid Binding Ig-like Lectin 2 / genetics T-Lymphocytes / transplantation
Antigens, CD19 / genetics Genetic Therapy Immunotherapy, Adoptive Interleukin-15 / genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy Receptors, Chimeric Antigen / genetics Sialic Acid Binding Ig-like Lectin 2 / genetics T-Lymphocytes / transplantation Case Reports Research Support, Non-U.S. Gov't Adult Antigens, CD19 / metabolism Disease Progression Humans Interleukin-15 / metabolism Male Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / immunology Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / metabolism Receptors, Chimeric Antigen / metabolism Retreatment Sialic Acid Binding Ig-like Lectin 2 / metabolism T-Lymphocytes / immunology T-Lymphocytes / metabolism Time Factors Treatment Outcome Antigens, CD19 CD19 molecule, human CD22 protein, human IL15 protein, human Interleukin-15 Receptors, Chimeric Antigen Sialic Acid Binding Ig-like Lectin 2
PMC8530183
34691036
CD19 CAR-T Cells With Membrane-Bound IL-15 for B-Cell Acute Lymphoblastic Leukemia After Failure of CD19 and CD22 CAR-T Cells: Case Report
2021