Hua Xu Melinda C Aldrich Qingxia Chen Hongfang Liu Neeraja B Peterson Qi Dai Mia Levy Anushi Shah Xue Han Xiaoyang Ruan Min Jiang Ying Li Jamii St Julien Jeremy Warner Carol Friedman Dan M Roden Joshua C Denny
10.1136/amiajnl-2014-002649
J Am Med Inform Assoc
2015 Jan;22(1):179-91.
drug repurposing electronic health records metformin natural language processing
CC BY-NC
https://pubmed.ncbi.nlm.nih.gov/25053577/
Drug Repositioning Electronic Health Records Hypoglycemic Agents / therapeutic use Information Storage and Retrieval / methods Metformin / therapeutic use Neoplasms / mortality
Drug Repositioning Electronic Health Records Hypoglycemic Agents / therapeutic use Information Storage and Retrieval / methods Metformin / therapeutic use Neoplasms / mortality Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Administration, Oral Adult Diabetes Mellitus, Type 2 / complications Diabetes Mellitus, Type 2 / drug therapy Diabetes Mellitus, Type 2 / mortality Humans Natural Language Processing Neoplasms / complications Neoplasms / prevention & control Registries Survival Analysis Hypoglycemic Agents Metformin
PMC4433365
25053577
Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality
2015