Barbara Namer Diana Schmidt Esther Eberhardt Michele Maroni Eva Dorfmeister Inge Petter Kleggetveit Luisa Kaluza Jannis Meents Aaron Gerlach Zhixin Lin Andreas Winterpacht Elena Dragicevic Zacharias Kohl Jürgen Schüttler Ingo Kurth Torhild Warncke Ellen Jorum Beate Winner Angelika Lampert
10.1016/j.ebiom.2018.11.042
EBioMedicine
2019 Jan;39:401-408.
human nociceptors microneurography multi-electrode-array patch-clamp personalized therapy small fiber neuropathy
CC BY-NC-ND
https://pubmed.ncbi.nlm.nih.gov/30503201/
Induced Pluripotent Stem Cells / cytology Lacosamide / administration & dosage Nociceptors / cytology Small Fiber Neuropathy / drug therapy
Induced Pluripotent Stem Cells / cytology Lacosamide / administration & dosage Nociceptors / cytology Small Fiber Neuropathy / drug therapy Case Reports Aged Cells, Cultured Female Humans Induced Pluripotent Stem Cells / drug effects Lacosamide / pharmacology Models, Biological Nociceptors / drug effects Pain Measurement Precision Medicine Translational Research, Biomedical Lacosamide
PMC6354557
30503201
Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors
2019