Christian Ulrich Huebbers Simon Florian Preuss Jutta Kolligs Julia Vent Markus Stenner Ulrike Wieland Steffi Silling Uta Drebber Ernst-Jan M Speel Jens Peter Klussmann
10.1371/journal.pone.0057207
PLoS One
2013;8(2):e57207.
CC BY
https://pubmed.ncbi.nlm.nih.gov/23437342/
3-Hydroxysteroid Dehydrogenases / genetics Carcinoma / genetics Cell Transformation, Neoplastic / genetics Human papillomavirus 6 / genetics Hydroxyprostaglandin Dehydrogenases / genetics Laryngeal Neoplasms / genetics Papilloma / genetics
3-Hydroxysteroid Dehydrogenases / genetics Carcinoma / genetics Cell Transformation, Neoplastic / genetics Human papillomavirus 6 / genetics Hydroxyprostaglandin Dehydrogenases / genetics Laryngeal Neoplasms / genetics Papilloma / genetics Case Reports Research Support, Non-U.S. Gov't Adult Age of Onset Aldo-Keto Reductase Family 1 Member C3 Carcinoma / pathology Cell Transformation, Neoplastic / pathology Cyclin-Dependent Kinase Inhibitor p16 / genetics Down-Regulation Fatal Outcome Female Human papillomavirus 6 / pathogenicity Humans Laryngeal Neoplasms / pathology Papilloma / pathology Retinoblastoma Protein / genetics Tumor Suppressor Protein p53 / genetics Cyclin-Dependent Kinase Inhibitor p16 Retinoblastoma Protein Tumor Suppressor Protein p53 3-Hydroxysteroid Dehydrogenases Hydroxyprostaglandin Dehydrogenases AKR1C3 protein, human Aldo-Keto Reductase Family 1 Member C3 Laryngeal papillomatosis
PMC3577740
23437342
Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis
2013