PMC3944654_01
(a) Ultrasound showing enlargement of the transplanted kidney; (b) CT scan of the chest showing a cystic mass in the lower lobe of the left lung (white arrow).
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Renal ultrasound showed an enlarged transplanted kidney (Figure 1). Computed tomography (CT) of the chest showed bilateral ground-glass infiltrates, multiple nodular opacities, and a 3.1 x 3 cm cystic mass in the lower lobe of the left lung (Figure 1).
Light microscopy of the transplanted kidney biopsy ((a), Jones stain, 400x) and lung tissue ((b), PAS stain, 400x) showing fungal hyphae. (c) Necrotic and hemorrhagic lesion in the right cerebral hemisphere.
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Numerous branching nonseptate fungal hyphae were seen throughout the renal tissue (Figure 2). Brain involvement was noted by the presence of a 6 x 5 x 5 cm hemorrhagic and necrotic lesion in the right cerebral hemisphere with obliteration of blood vessels by matted fungal hyphae (Figure 2). Mycocladus corymbifer (formerly Absidia corymbifera) was isolated on tissue cultures from the kidney biopsy and the lung tissue obtained by autopsy (Figure 2).