PMC3223989_01
(A) [99mTc] sodium pertechnetate scan shows a cold area in the upper right thyroid lobe. Early (B) and delayed (C) [99mTc] Sestamibi scans reveal a focal area of increased uptake in the upper right thyroid lobe, within the cold area detected by the thyroid [99mTc] sodium pertechnetate scan. (D) Processed image obtained by data subtraction of the [99mTc] Sestamibi scan from the [99mTc] sodium pertechnetate scan.
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A 99mTc-methoxyisobutylisonitrile (99mTc-Sestamibi) scan subsequently performed revealed a focal area of increased uptake in the right thyroid lobe, within the cold area detected by the thyroid scan (Figure 1B and C) and is clearly evident in the subtraction image (Figure 1D).