PMC5223751_01
Atypical menigeoma (Haematoxylin-Eosin [HE] stain).
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The histological examination including immunohistochemical profile showed an atypical meningioma WHO II  (Fig. 1, 2).
Mib1-stain.
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The histological examination including immunohistochemical profile showed an atypical meningioma WHO II  (Fig. 1, 2).
A : T1-weighted axial MR image after contrast administration showing the tumor before the last operation. B : T2-weighted sagittal MR image showing the tumor before the last operation. MR : magnetic resonance.
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After three years (2008) a recurrence of the tumor in the posterior horn of the left lateral ventricle was discovered on MRI Scans (Fig. 3A, B) at the same location as the tumor before (2002).
A : T1 weighted axial MR image after contrast administration showing the tumor in the quadrigeminal lamina. B : T1 weighted sagittal MR image after contrast administration showing the tumor in the quadrigeminal lamina. MR : magnetic resonance.
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Additionally, in this MRI another tumor located in the quadrigeminal lamina was detected (Fig. 4A, B).
Cavernoma. EVG stain. EVG : Elastica-van-Gieson.
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The pathological examination including immunohistochemical studies confirmed the diagnosis of a collision tumor consisting of components of a meningioma WHO II  and a cavernoma (Fig. 5).
EMA stain. EMA : epithelial membrane antigen.
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The tumor cells stained positively for the epithelial membrane antigene (EMA) (Fig. 6) and the evidence of cavernoma components was shown by positive expression of CD-34 of the epithelial cells (Fig. 7).
A : T1 weighted axial MR image after contrast administration after tumor extirpation. B : T1 weighted axial MR image after contrast administration, three year follow up. MR : magnetic resonance.
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