PMC5349031_01
Panoramic radiograph showing a radiopaque lesion in the right oral mucosa
(arrow)
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Epithelial acanthosis and brownish-black pigment deposits in the submucosal region
(arrow) (Hematoxylin and eosin, x100)
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Histopathological examination revealed epithelial acanthosis and brownish-black pigment deposits in the submucosa surrounded by a lymphocyte inflammatory infiltrate (Figure 2), and multinucleated giant cells phagocyting these pigments (Figure 3).
Multinucleated giant cells phagocyting brownish-black pigments (Hematoxylin and
eosin, x400)
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Histopathological examination revealed epithelial acanthosis and brownish-black pigment deposits in the submucosa surrounded by a lymphocyte inflammatory infiltrate (Figure 2), and multinucleated giant cells phagocyting these pigments (Figure 3).
Impregnation of muscle cells by brownish-black pigments (Hematoxylin and eosin,
x400)
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Muscle cells were impregnated in the deeper layers (Figure 4).