PMC9039612_01
Nasal scope at the first visit and after radiotherapy and chemotherapy. (A) First visit: left nasal concha occupied by the tumor. (B) Tumor remission after radiotherapy followed by nivolumab and ipilimumab therapy.
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F1
A nasal scope revealed an obstructive tumor in the left nasal concha (Figure 1A). Despite the tumor reduction (Figures 1B, 2B), his PS, mental status, and quality of life decreased after cancer remission.
Contrast computed tomography at the first visit and after radiotherapy and chemotherapy (A). First visit: The left nasal concha was obstructed by the tumor. (B) Tumor remission after radiotherapy followed by nivolumab and ipilimumab therapy.
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F2
Tissue biopsy showed malignant melanoma, and computed tomography (Figure 2A) showed the obstructed tumor at the left nasal concha with metastases in the liver and bone; thus, he was diagnosed with stage IV malignant melanoma. Despite the tumor reduction (Figures 1B, 2B), his PS, mental status, and quality of life decreased after cancer remission.
Clinical course of the treatment. Performance status is rated from 0 to 4 for fatigue (lethargy, malaise, and asthenia); 0: none, 1: increased fatigue over baseline, but not altering normal activities; 2: moderate or causing difficulty in performing some activities; 3: severe or loss of ability to perform some activities; 4: bedridden or disabled (Date, 1999).
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F3
Figure 3 shows the clinical course of the treatment.