PMC5726688_01
Multiple light brown-reddish grouped papules and nodules on the trunk,
back and extremities
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f1
A 20-year-old female patient presented with multiple light brown-reddish grouped papules and nodules symmetrically distributed on both the trunk and limbs (Figure 1).
A -Partially encapsulated epithelial tumor is seen on the right side and
normal renal parenchyma on the left side (Hematoxylin & eosin, X40);
Immunohistochemically, the tumor is positive for B -pancytokeratine,
(x40) C -vimentine (x100) and D -Anti-mitochondrial antibody (x100)
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f2
She had a history of bilateral nephrectomy performed when she was 13 and 16 years of age due to histologically confirmed bilateral papillary type 2 renal cell carcinoma (Figure 2).
A well-demarcated tumor composed of intersecting in the third decade. To
us, these family smooth muscle bundles is seen beneath the epidermis
(Hematoxylin & eosin, X40 magnification).
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f3
A biopsy was taken from one of the skin lesions which demonstrated typical histologic features of cutaneous leiomyomas and a diagnosis of piloleiomyoma with a type 2 segmental distribution was made (Figures 3 and 4).
Immunohistochemistry study showed that the lesion was positive for desmin
(A) - and smooth muscle antibidy (B) - Desmine antibody X40, Smooth
muscle antibody X40)
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f4
A biopsy was taken from one of the skin lesions which demonstrated typical histologic features of cutaneous leiomyomas and a diagnosis of piloleiomyoma with a type 2 segmental distribution was made (Figures 3 and 4).