PMC3357613_01
The clinical course of the index case with bacterial meningitis.The solid line and dashed line denote the body temperature and urinary calcium excretion, respectively. uCa/Cr, urinary calcium to creatinine ratio; DEXA, dexamethasone.
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F1
As shown in Figure 1, both ceftriaxone (120 mg/kg per day) and meropenem (120 mg/kg per day) were administered in two equal intravenous doses over 60 min. After discontinuation, no further white turbidity of the urine was noted, and the uCa/Cr gradually normalized in parallel with the recovery from bacterial meningitis, as shown in Figure 1.
A photograph of the white turbid urine excreted after 13 days of ceftriaxone therapy. The urinary crystalline precipitates shown were confirmed to be ceftriaxone-calcium precipitates. The subject's serum calcium level was normal (9.6 mg/dL), while his urinary calcium to creatinine ratio was high at 0.97 (normal for age: 0.60). A, distilled water for contrast; B, patient's urine.
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F2
On the 13th day of ceftriaxone therapy, the patient produced white turbid urine (Figure 2).