PMC4745328_01
The surgically resected specimen consisted of clear cell renal carcinoma with tumor thrombus (arrow).
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fig1
Evaluation of the nephrectomy specimen revealed a 7 cm Fuhrman grade 2 clear cell RCC invading the renal vein with lymphovascular invasion and clear surgical margins without invasion of Gerota's fascia or the renal sinus (T3aN0M0) (Figure 1).
Histological examination (hematoxylin-eosin staining; magnification 4x) of the resected small bowel specimen showing a neuroendocrine carcinoma composed of islands of uniform cells embedded within fibrous tissue.
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fig2
The resected small bowel specimen demonstrated a 2.5 cm ileal mass with multiple foci of intermediate grade neuroendocrine carcinoma (G2 with 12 mitoses per high-power field) seen in Figure 2 penetrating the serosal surface of the bowel with both lymphovascular and perineural invasion.
PMC4745328_02
CT scans reveal a partially enhancing mass ((a) arrow) located on the upper pole of the left kidney. The presence of para-aortic lymphadenopathy ((b) arrowhead) as well as a prominent appendiceal mass ((c) arrow) was also noted.
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fig3
Initial CT scan showed an enlarged appendix and a partially exophytic, enhancing mass located in the upper pole of the left kidney with an enlarged para-aortic lymph node (Figure 3).
PMC4745328_03
Histological examination (hematoxylin-eosin staining; magnification 3x) of the resected large bowel specimen showing a moderately differentiated adenocarcinoma invading into the submucosa.
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fig4
The resected large bowel specimens demonstrated tubular adenoma present in the cecum and hepatic flexure; also noted was moderately differentiated invasive adenocarcinoma extending into the submucosa of the transverse colon (T1N0M0) (Figure 4).