PMC5377439_01
Chest x-ray and computed tomography (CT) (a) prior to admission: Honeycombing, along with traction bronchiestasis in the subpleural and basal areas of both lungs, was detected; (b) at admission: Compared to pre-admission, chest x-ray revealed new bilateral diffuse infiltrates (with the relatively lateral to intermediate areas shown to be significant), suggesting marked progression of idiopathic pulmonary fibrosis (IPF).
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Blood samples demonstrated increases in serum markers, LDH, KL-6, and SP-D following the inflammatory response, which led to the patient being diagnosed as having an acute exacerbation of IP (Fig. 1).