PMC3245190_01
Color fundus photograph (upper panel), corresponding fluorescein angiography (middle), and optical coherence tomography (lower) of the left eye in patient #1 with adult Coats' disease: (A) at the initial visit; (B) 1 year after treatment of retinal photocoagulation; (C) 11 years after treatment.
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At the initial visit (Figure 1A), fundus examination revealed thick subretinal exudates extended to and threatening the fovea, and fluorescein angiography (FA) showed telangiectatic vessels with fluorescein leakage, numerous microaneurysms, and areas of capillary nonperfusion. FA indicated marked reduction of fluorescein leakage from abnormal retinal vessels compared to the previous status, and OCT presented a disappearance of exudative retinal detachment (Figure 1B).
PMC3245190_02
Color fundus photograph (upper panel), corresponding fluorescein angiography (lower) of the right eye in patient #2 with adult Coats' disease. (A) At the initial visit; (B) 3 months after treatment of retinal photocoagulation and cryotherapy; (C) 10 years after treatment (FA image not available).
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At his initial visit, the best-corrected visual acuity of his right eye was 12/20 and the fundus examination and FA revealed severe lipid exudation and multiple telangiectatic vessels found on the overall retina with exudative retinal detachment (Figure 2A). Three months after that, lipid exudation was settled with the disappearance of exudative detachment, and visual acuity improved to 20/200 (Figure 2B). At a follow-up 10 years after the treatment, subretinal exudation was diminished and the right VA remained at 20/200 (Figure 2C).