PMC6120426_01
Changes in amygdala volume in coronal fluid-attenuated inversion recovery MRI images.. (a) Enlargement of and high signal intensity in the left amygdala (arrow) are detected at initial hospitalization (Baseline). (b) MRI conducted after 12 months of cessation of seizures shows reduction of left amygdala enlargement. (C) MRI obtained after 24 months of cessation of seizures shows remission of amygdala enlargement and recovery of hyperintensity.
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Magnetic resonance imaging (MRI) indicated left AE with hyperintense T2/fluid-attenuated inversion recovery signal (Fig. 1) upon visual inspection by a certificated radiologist and a certificated epileptologist.
PMC6120426_02
Chronological change of neuropsychological examinations.. (a) WAIS-III: Changes in IQ score reveal remarkable improvement in verbal IQ and increase in full IQ score after the cessation of seizures (left). Verbal comprehension and working memory are particularly improved after the cessation of seizures in subcategories of WAIS-III (right).. (b) WMS-R scores: Attention/concentration scores decreased transiently, but in other categories of memory function, significant improvement was recognized after the cessation of seizures.. Neuropsychological examinations reveal the changes in the patient's verbal IQ and memory as the left temporal function was particularly improved after the cessation of seizures due to appropriate ASD.. WAIS-III: Wechsler Adult Intelligence Scale - Third Edition, WMS-R: Wechsler Memory Scale - Revised, IQ: Intelligence Quotient.
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During a 3-year follow-up, she maintained seizure freedom on ZNS 200 mg daily, and neuropsychological examination revealed that her verbal intelligence quotient and memory functions were particularly improved (Fig. 2).