PMC5343232_01
Initial clinical presentation of the patient. Swelling in the floor of the mouth.
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Intraoral physical examination showed a mucosa colored swelling of hard consistency in the left sublingual region that measured approximately 3 cm in its greatest diameter (Figure 1).
Ultrasonography of the salivary glands. A nodular image of low echogenicity measuring about 2.7 x 1.8 cm was detected.
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During this exam, a nodular image of low echogenicity measuring about 2.7 x 1.8 cm was detected (Figure 2).
Surgical specimen. Surgical specimen measuring 3 cm in its greatest diameter upon macroscopic inspection.
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An excisional biopsy was performed and analysis of the surgical specimen revealed an encapsulated, oval lesion with a smooth surface and brown color (Figure 3).
Histopathological features (hematoxylin-eosin). (a) Fragment of the mesenchymal neoplasm showing the proliferation of spindle-shaped cells. The tumor appeared as a well-circumscribed mass with a fibrous capsule. (b) Rich vascularization with hypocellular and hypercellular areas. (c) Enlarged view of spindle-shaped cells exhibiting mild pleomorphism in focal areas.
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The tumor was highly vascularized and its stroma exhibited richly collagenized fibrous connective tissue and myxoid areas (Figure 4).
Immunohistochemistry. (a) Positive staining for CD34. (b) Positive staining for CD99.
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Based on the combination of histopathological and immunohistochemical features, the final diagnosis was SFT (Figure 5).