PMC3551720_01
Anterior segment of the eye. A, large keratic precipitates on the corneal endothelium. B, a mild anterior chamber cellular reaction.
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F1
There were large keratic precipitates and a mild anterior chamber cellular reaction present in both eyes (Figure 1).
A photograph of the fundus. A, right eye. B, left eye. Apparent are retinal infiltrates and retinal necrosis, a pale optic disc, several hemorrhages in the posterior pole and white sheathing of some vessels.
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F2
Some vessels displayed extensive white sheathing providing them with the appearance of frosted branch angiitis (Figure 2).
Results of cytologic examination of vitreous fluid. A, atypical lymphocytes highly suspected of NHL. B, syntitium of atypical lymphocytes in vitreous body. Microscope Olympus BX51, digital camera E-510. Objective 100x, num.ap. 1.4. May-Gruenwald-Giemsa staining.
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F3
Furthermore, cytologic examination revealed atypical lymphocytes with lobulated nuclei and basophilic cytoplasma (Figure 3) on a background of lytic cells.
Results of perimetry. A, right eye. B, left eye. Large visual fields defects.
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F4
However, BCVA decreased to 6/24 in the right eye and 6/12 in the left eye, perimetry revealed scotomas (Figure 4) and moderate vitreous haze persisted in the left eye (Figure 5).
Vitreous haze in the left eye.
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F5
However, BCVA decreased to 6/24 in the right eye and 6/12 in the left eye, perimetry revealed scotomas (Figure 4) and moderate vitreous haze persisted in the left eye (Figure 5).
Perimetry with progression of visual fields defects. A, right eye. B, left eye.
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F6
BCVA reduced to hand movements in the right eye and 6/18 in the left eye and further progression of visual field defects was demonstrated (Figure 6).
Time course of CMV DNA copies in plasma. Three-week long continuous intravenous foscarnet was applied in June, July and October, 2010. During September the patient was treated with foscarnet administered as a bolus three times per week.
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F7
Moreover, an increase in plasmatic CMV DNA copies was detected (Figure 7).
A photograph of the fundus with retinal lesions in regression. A, right eye. A pale optic disc and fibrosis of some vessels. B, left eye. A pale optic disc and persisting moderate vitreous haze.
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F8
Patient follow-up was scheduled for every 8-10 weeks as retinal lesions were inactive (Figure 8).