PMC5863027_01
Pelvic MRI of patient no. 1. Bilaterally cystic structures in or around the Bartholin's gland and a large accumulation of 'liquid' in the stroma of the labium majus at the right side.
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In addition, a cystic structure of more than 6 cm length was observed in the right labium majus directly underneath the skin [Fig. 1, Fig. 2].
Aspect of the vulva of patient no. 1, before the second surgical intervention. Prominent contour of the lower medial kwadrant of the right labium, caused by accumulation of subcutaneous mucus.
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Upon inspection, the right labium showed a prominent contour with a diffuse and soft consistency underneath, apparently as a result of subcutaneous mucus [Fig. 3].
Patient no. 1. Transcutaneous incision through the labiocrural fold. Nodule of Bartholin's gland is excised.
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In a repeat procedure, with an incision through the labio-crural fold, the mucus was drained and the nodule excised [Fig. 4].
Nodular hyperplasia at low power of casus 1. There is an increased number of glands with a preserved architecture with numerous acini lined with columnar epithelium ( ). The secretion of the acini empties into the Bartholin's duct. In nodular hyperplasia, destruction of the glands with coexisting inflammation, free mucus and mucus-laden macrophages in the stroma (*) and squamous metaplasia (inlet) are often observed.
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Histology again showed nodular hyperplasia [Fig. 5].