PMC8278989_01
PMC8278989_02
High-resolution computed tomography scan of the chest.. (A) Pre-treatment scan showing
extensive, bilateral ground-glass opacities (GGO) and . (B) in the resolution phase, after treatment
with corticosteroids, showing improvement in the GGO globally but with persistence of some
centrilobular ground-glass nodules in the right lung posteriorly.
AJTCCM-25-2-010-fig1.jpg
PMC8278989_04_AJTCCM-25-2-010-fig1.jpg
F1
Both patients showed radiological resolution (Fig. 1B) and an improvement in FEV1 to baseline post treatment. 
PMC8278989_03
Transbronchial lung biopsies (haematoxylin and eosin staining)..  (A) Well-expanded airspaces with discrete perivascular cellular infiltrates, grade A2 (40x).. (B) Multiple layers of lymphocytes surrounding a pulmonary venule, grade A2 (200x). . (C) Sub-endothelial lymphocytes expanding an alveolar septum and associated endothelialitis grade A3..  (D) A bronchiole with scanty submucosal lymphocytes showing grade B1R rejection (400x).
AJTCCM-25-2-010-fig2.jpg
PMC8278989_03_AJTCCM-25-2-010-fig2.jpg
F2
In the first patient, the histological grade was A2B0, and in the second, the histological grade was A3B1R (Fig. 2).
PMC8278989_04
High-resolution computed tomography scan of the chest.. (A) Pre-treatment scan showing
extensive, bilateral ground-glass opacities (GGO) and . (B) in the resolution phase, after treatment
with corticosteroids, showing improvement in the GGO globally but with persistence of some
centrilobular ground-glass nodules in the right lung posteriorly.
AJTCCM-25-2-010-fig1.jpg
PMC8278989_04_AJTCCM-25-2-010-fig1.jpg
F1
Both patients showed radiological resolution (Fig. 1B) and an improvement in FEV1 to baseline post treatment. 