PMC7318809_01
MRI brain with gadolinium demonstrating a 6.3 x 4.5 x 4.2 cm metastatic mass in the right occipital lobe.
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A subsequent brain magnetic resonance imaging (MRI) showed a 4.2 cm, large, irregular tumor in the right occipital lobe (Figure 1).
(a) Basaloid squamous cell carcinoma metastasis of the right occipital lobe. (b) Strong nuclear and cytoplasmic positivity with p16 immunohistochemical stain, corresponding with DNA presence of HPV subtype 16.
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Identical features of BSCC were present in all samples (Figure 2(a)). P16 immunohistochemistry was performed on samples from the brain lesions, which showed strong and diffuse cytoplasmic and nuclear positivity (Figure 2(b)).