PMC3504231_01
CT scan of the thorax showing the enlarged mediastinal mass in front of the aortic arch.
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fig1
Contrast-enhanced chest CT scan due to worsening dyspnoea in October 2009 revealed an enlargement of the mediastinum (Figure 1).
(a) Thymic tissue with adjacent mature fat (hematoxylin and eosin, original magnification x4). (b) Hyperplastic thymus with lobular structure, divorcing fibrous septa, sometimes interrupted by mature fat and enclosed hyperemic vessels (hematoxylin and eosin, original magnification x4). (c) Thymic tissue with prominent enlarged Hassall's corpuscles (hematoxylin and eosin, original magnification x20). (d) Immunohistochemistry shows CD20 positivity for B lymphocytes surrounding Hassall's corpuscles (original magnification x20, methylen blue counterstain). (e) Strong Ki-67 positivity, which demonstrates the high proliferation rate of the cellular elements of thymic tissue. The staining relieves the areas surrounding the Hassall's corpuscles (original magnification x4, methylen blue counterstain).
CRIM.TRANSPLANTATION2011-859405.002.jpg
PMC3504231_01_CRIM.TRANSPLANTATION2011-859405.002.jpg
fig2