PMC3263563_01
Participant no. 1 with a left temporoparietal lesion. The CT image in (a) depicts an axial scan through the maximum width of the lesion in the left angular gyrus. The dark area within the confines of the left hemisphere shows surgical evacuation of infarcted tissue within the left temporoparietal cortex. The CT image in (b) depicts the maximal width of the lesion in the left inferior temporal lobe. According to neuroradiological convention left side of the image is the right hemisphere and the right side of the image is the left hemisphere.
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fig1
Participant 1 was a 57-year-old right-handed female with one year of college that had sustained a severe left temporoparietal stroke as a result of left middle cerebral artery occlusion (Figure 1). In the absence of an impaired effect for Figure Weights by participant 1, a further inference would be that Figure Weights could well be more heavily dependent on the integrity of neural substrates distributed within the right hemisphere.
PMC3263563_02
Participant no. 2 with a left frontal lobe lesion. The CT image in (a) depicts the extensive left inferior frontal lobe lesion occurring as a result of an anterior communicating artery aneurysm. The CT image in (b) depicts the same lesion extending contiguously to include the infarcted tissue in the left anterior superior frontal lobe.
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fig2
Participant 2 was a 64-year-old right-handed male with five years of college education that had sustained a large infarct in the left inferior frontal lobe as a result of an anterior communicating artery aneurysm (Figure 2). Verbal Working Memory Index (P < .05) see Table 3. Verbal working memory has been previously shown to involve left lateral prefrontal and left parietal neural substrates, and consistent with these findings, portions of the left superior prefrontal cortex were unambiguously damaged in participant 2 (Figure 2). 
PMC3263563_03
Participant no. 3 with a right frontotemporal lesion. The CT image in (a) depicts a large lesion within the right anterior inferior medial temporal lobe with incursion of the lesion to include both straight gyri of the orbitofrontal lobes. The CT image in (b) depicts bilateral lesions in the cortex underlying the anterior-inferior cingulate gyri. Although the lesions are bilateral, (and this poses some degree of difficulty in making firm conclusions), the lesions are significantly larger and of greater extent in the right hemisphere.
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fig3
Participant 3 was a 35-year-old right-handed female with five years of college that had sustained a predominately right inferior frontal-temporal lobe localized infarct after an anterior communicating artery aneurysm (Figure 3).
PMC3263563_04
Participant no. 4 with a right thalamic lesion. The MRI image in (a) depicts a calcified third ventricular mass occluding the third ventricle which was subsequently resected. Lateral ventricular dilation is evident. The CT image in (b) depicts resolution of ventricular dilatation subsequent to tumour resection and reopening of the cerebrospinal fluid cisterns. However, (b) shows a right posterior thalamic ischemic infarct appearing two weeks after resection of the third ventricular tumour.
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fig4
Participant 4 was a 23-year-old right-handed male with 5 years of college that had sustained a right posterior thalamic infarct after a third ventricle tumor (Figure 4).
PMC3263563_05
Participant no. 5 with a right temporoparietal lesion. The CT image in (a) depicts severe damage to the right inferior parietal lobe and right temporoparietal junction. The CT image in (b) shows the downward extension of the lesion into the right superior temporal gyrus. The dark areas in (a) and (b) panels illustrate evacuation of infarcted brain tissue by neurosurgery.
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fig5
Participant 5 was a 40-year-old left-handed male with two years of postsecondary technical training who sustained a large right temporoparietal lesion (Figure 5).