PMC7682605_01
(A,C,E,G) Chest CT showed a 5.2x5.8cm mass in the upper lobe of the right lung. (B,D,F,H) After 50Gy/25 fractions of radiotherapy, the tumor shrank significantly on the radiograph.
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Meanwhile, the right hilar lymph nodes were enlarged and enhanced (Figure 1A,C,E,G). After 50Gy/25 fractions of radiotherapy, the tumor shrank significantly on the CT scan (Figure 1B,D,F,H).
Histological and immunohistochemical findings. (A) Heteromorphic cells were seen to be nest-like or lamellar with dense arrangement and hyperchromatic nuclei (hematoxylin and eosin staining, x100); (B) Immunohistochemical staining for CK shows focal positivity (x100); (C) Immunohistochemical staining for CK7 shows focal positivity (x100); (D) Immunohistochemical staining for PAS-AB shows focal positivity (x100); (E) Immunohistochemical staining for Vimentin shows focal positivity (x100); (F) Immunohistochemical staining for Hepatocyte shows focal positivity (x100); (G) Immunohistochemical staining for TTF-1 shows negativity (x100); (H) Immunohistochemical staining for Ki-67 shows 60% positivity (x100).
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Microscopically, heteromorphic cells were seen to be nest-like or lamellar with dense arrangement and hyperchromatic nuclei (Figure 2A). Hepatocyte(+), Napsin-A(-), TTF-1(-), Ki-67 (60%) (Figure 2B-H). CD56, CD31, Desmin,
The changes in complete blood count (WBC, lymphocyte and granulocyte) depended on the date (days 0-30).
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The changes in complete blood count during radiotherapy are shown in Figure 3.