PMC8825631_01
(a) Erythematous plaques with central ulceration on both legs. (b) Skin biopsy of the border of an ulcer. In the deep reticular dermis, there is a medium artery with prominent fibrinoid necrosis and inflammation, consistent with a necrotizing arteritis (hematoxylin-eosin stain; magnification x100).
10.1177_2050313X20953110-fig1.jpg
PMC8825631_01_10.1177_2050313X20953110-fig1.jpg
fig1-2050313X20953110
Her cutaneous examination revealed multiple indurated plaques with central ulceration on both legs (Figure 1(a)). A biopsy at the border of the ulcer revealed a necrotizing medium vessel arteritis present in the dermis most suspicious of PAN (Figure 1(b)).
(a) Multiple yellowish papules on the posterior neck. (b) Skin biopsy of the yellowish papules on the posterior neck shows pseudoxanthoma elasticum-like calcification of the elastic fibers (Von Kossa stain; magnification x40).
10.1177_2050313X20953110-fig2.jpg
PMC8825631_01_10.1177_2050313X20953110-fig2.jpg
fig2-2050313X20953110
Coincidentally, she was also noted to have multiple yellowish papules diffusely scattered on the posterior neck (Figure 2(a)). Von Kossa stain highlighted the clumped elastic fibers (Figure 2(b)).