PMC8666490_01
Tumour with uniform population of neoplastic cells with fine granular chromatin pattern and inconspicuous small nucleoli (H&E, 200x).
JAFES-36-2-220-g001.jpg
PMC8666490_01_JAFES-36-2-220-g001.jpg
f0001
He underwent left lower lobe lobectomy and histopathology confirmed to be NET with synaptophysin positivity and Ki-67 <2% (Grade 1) (Figures 1 and 2).
Tumour cells showing diffuse positivity for synaptophysin (SYN, 100x).
JAFES-36-2-220-g002.jpg
PMC8666490_01_JAFES-36-2-220-g002.jpg
f0002
He underwent left lower lobe lobectomy and histopathology confirmed to be NET with synaptophysin positivity and Ki-67 <2% (Grade 1) (Figures 1 and 2).
(A) Galium-68 DOTANOC scan showing somatostatin-avid disease in left lower lobe of lung mass and heterogenous uptake in both lobes of liver and vertebra spine; (B) Galium-68 DOTANOC imaging post left lung lobectomy and lanreotide therapy showing disease progression with increasing somatostatin-avid lesions in liver, vertebrae, pelvic, ribs and scapula; (C) Post PRRT scan showing high tumour burden with increased somatostatin-avid lesions in neck, both lung fields and abdomen.
JAFES-36-2-220-g003.jpg
PMC8666490_01_JAFES-36-2-220-g003.jpg
f0003
Repeated Galium scan showed disease progression and extensive metastases (Figure 3).