PMC5606293_01
First F-FDG performed; intense and diffuse tracer uptake in the spleen and hilar lymph nodes.
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MBq (6.5 mCi) of 18F-FDG according to the body mass index. Maximum-intensity projection PET image (A), axial CT (B), and fused PET/CT images (C,D) (Figure 1) showed intense and diffuse tracer uptake in the spleen (red arrow), which had an homogeneous parenchymal structure without focal nodular lesions and, in mediastinal field, multiple FDG avid bilateral hilar lymph nodes characterised by greater lymph node enlargement on the right side.
Histological features showing non-caseating granuloma between the mucinous bronchial glands (A) and submucosal granuloma consisting of a nodular cluster of epithelioid and giant cells (B).
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Histological features were compatible with sarcoidosis showing noncaseating granuloma between the mucinous bronchial glands (A) and submucosal granuloma consisting of a nodular cluster of epithelioid and giant cells (B) (Figure 2).
PET-CT after treatment that shows a rapid decrease of FDG uptake.
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