PMC3566941_01
NSCLC renal metastasis. Computed tomography scan (A) and enhanced scan (B).
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F1
After 10 months of disease free interval, a routine urine test showed WBC 20 and RBC 5-10 per high-power field; enhanced CT scan showed an occupying lesion in the left renal parenchyma and paraaortic lymph node enlargement (Figure 1), while brain MRI and liver CT scan showed no other distant metastasis.
NSCLC renal metastasis. Renal biopsy specimen : Hematoxylin-eosin staining (A) and immunohistochemical staining of 34betaE12 (B), CK5/6 (C) and TTF-1(D).
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F2
In addition, B ultrasound guided left kidney biopsy was performed and immunohistochemical staining of the biopsy specimen showed: metastatic squamous cell lung carcinoma, with the same positive tumor biomarkers as in the surgical lung sample (Figure 2).