PMC10342198_01
(A, B) Pre-treatment photograph. (C, D) Post-treatment photograph.
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F1
The antibiotics had no apparent effect; in fact, erythema and pustules arose on day 10 of antibiotic treatment (Figure 1). The pustules were distributed symmetrically and were most numerous on the trunk and face and, to a lesser extent, on the hands and feet (Figure 1).
(A) Pustules on the right side of the chest. (B) Histopathology on the right side of the chest.
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F2
The histologic evaluation of a biopsy specimen from the skin on the right side of the chest revealed a sub-corneal pustule and a perivascular lymphocytic infiltrate in the upper dermis (Figure 2). The patient was initially treated with levofloxacin hydrochloride injection (0.4 g once daily for 6 days), and azithromycin injection (0.5 g once daily for 6 days), but no significant improvement was observed. methylprednisolone sodium succinate injection (40 mg once daily for 8 days)was administered, the erythema and pustules completely disappeared, and the presenting symptoms resolved (Figure 2).