PMC3130998_01
Physical examination demonstrated multiple yellowish to reddish-brown nodules and plaques on face (a) and extremities (b). Some lesions were observed to have central ulceration and atrophy (c).
DRP2011-927852.001.jpg
PMC3130998_01_DRP2011-927852.001.jpg
fig1
Physical examination showed multiple yellowish to reddish-brown nodules and plaques on face and extremities (Figures 1(a) and 1(b)). Some lesions were observed to have central ulceration and atrophy distributed on her legs and forearms (Figure 1(c)), healing with scar.
Histopathology (Hematoxylin & Eosin staining) revealed diffuse infiltration from papillary dermis to superficial subcutaneous fat by mononuclear cells (H&Ex12.5) (a). Palisaded granuloma with necrobiosis is also noted (H&Ex200) (b). Xanthoma cells and Touton giant cells (c) and cholesterol clefts (d) are seen (H&Ex400).
DRP2011-927852.002.jpg
PMC3130998_01_DRP2011-927852.002.jpg
fig2
Cholesteral clefts were found in the center of necrobiotic area (Figure 2).