PMC6114064_01
Normal region in the tumor margin. Arrows mark the immunoexpression of p53 in some focal areas in the basal layer with weak nuclear staining (200x Magnification).
CRIPA2018-8428395.001.jpg
PMC6114064_01_CRIPA2018-8428395.001.jpg
fig1
The tissue adjacent to the lesion was evaluated with immunohistochemical staining for p53 (Figure 1) with some focal areas in the basal and suprabasal layer with weak nuclear staining and Ki-67 (Figure 2) with the positivity of basal and suprabasal layer.
Normal region adjacent to the tumor. Arrows indicate positivity for Ki-67 in some focal areas with poor nuclear marking at the basal layer (200x Magnification).
CRIPA2018-8428395.002.jpg
PMC6114064_01_CRIPA2018-8428395.002.jpg
fig2
The tissue adjacent to the lesion was evaluated with immunohistochemical staining for p53 (Figure 1) with some focal areas in the basal and suprabasal layer with weak nuclear staining and Ki-67 (Figure 2) with the positivity of basal and suprabasal layer.
(A) Increased immunoreactivity of the p53 protein from the adjacent region towards the tumor region (less magnification); (B) transition area. Arrows indicate marking of nuclei to p53 in a region adjacent to the tumor; asterisk marks tumor region (highest magnification).
CRIPA2018-8428395.003.jpg
PMC6114064_01_CRIPA2018-8428395.003.jpg
fig3
The tissue adjacent to the uvula expressed diffuse immunoreactivity for p53 (Figure 3) and Ki-67 (Figure 4) with strong nuclear staining in the basal and suprabasal layer.
(A) Strong and diffuse immunoreactivity for Ki-67 in the region adjacent to the tumor (less magnification); (B) transition area. Arrows indicate nucleation markers for Ki-67 in the region adjacent to the tumor; asterisk marks tumor region (highest magnification).
CRIPA2018-8428395.004.jpg
PMC6114064_01_CRIPA2018-8428395.004.jpg
fig4
The tissue adjacent to the uvula expressed diffuse immunoreactivity for p53 (Figure 3) and Ki-67 (Figure 4) with strong nuclear staining in the basal and suprabasal layer.