PMC5241495_01
Two offsprings of the family, with Pelizaeus-Merzbacher Disorder. Note spastic posturing.
CRIG2017-2706098.001.jpg
PMC5241495_01_CRIG2017-2706098.001.jpg
fig1
Here we present a 9-year-old Iranian boy (Figure 1) to unrelated apparently healthy parents. He had an older brother aged 15 years (Figure 1) and a maternal uncle with similar clinical features.
Brain MRI of the patient shows cerebral atrophy. Note hypomyelination and leukodystrophy.
CRIG2017-2706098.002.jpg
PMC5241495_01_CRIG2017-2706098.002.jpg
fig2
Brain MRI reported cerebral atrophy (Figure 2).