PMC2822254_01
The cut surface of the mass shows numerous cysts, measuring up to 1.2 cm in diameter, with a gelatinous secretion.
jkms-19-149-g001.jpg
PMC2822254_01_jkms-19-149-g001.jpg
F1
The individual cysts varied from 0.1 cm to 1.2 cm in dimension (Fig. 1).
Microscopic findings. The lesion is composed of multiple cysts and ducts containing eosinophilic secretion (A, H&E, x20). Most of the cysts are lined by flat epithelium. The secretion retracts from the surrounding epithelium (B, H&E, x200). The epithelium of some cysts grows as micropapillary intraductal carcinoma (C, H&E, x200). An invasive component (arrow) is found adjacent to the intraductal carcinoma component (D, H&E, x100).
jkms-19-149-g002.jpg
PMC2822254_01_jkms-19-149-g002.jpg
F2
The homogeneous secretions were retracted from the surrounding epithelia, producing scalloped margins (Fig. 2A). The lining of the cysts in most areas was of flat or cuboidal epithelium and devoid of cellular atypia (Fig. 2B). The epithelium of some cysts showed proliferative change ranging from atypical hyperplasia to intraductal carcinoma, micropapillary type (Fig. 2C). The intraductal carcinoma component was accompanied by an invasive component with small solid nests (Fig. 2D).