PMC3554996_01
Color fundus image and a HRA2 cSLO fundus autofluorescence (FAF) image of the left eye. Multiple serous retinal detachments are observed after recurrence (a), A "sunset glow" sign is not observed 1 month after recurrence (b), "Sunset glow" sign begins to appear 2 months after recurrence (c), At 3 months (d-f) and 5 months (g-i) after recurrence, short wavelength FAF (SW-FAF) image (e, h) shows normal background AF with multiple focal granular hyper-AF, and near infrared FAF (NI-FAF) image (f, i) shows decreased background AF with multiple, focal granular hyper-AF signals
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F1
A 55-year-old man complaining of recurring obscured vision in both eyes presented to our clinic during his second episode of Vogt-Koyanagi-Harada (VKH) disease [Fig. 1a]. At 2 months after recurrence, a "sunset glow" change of the fundus was observed [Fig. 1c]. Upon fundus autofluorescence (FAF) imaging taken 3 months after recurrence, short wavelength FAF (SW-FAF) images revealed normal background autofluorescence (AF) with multiple focal granular hyper-AF signals [Fig. 1e], while near infrared FAF (NI-FAF) images demonstrated decreased background AF with multiple focal granular hyper-AF signals [Fig. 1f]. On FAF images taken 5 months after recurrence, several previous hyper-AF signals on both images had become weak or had disappeared [Fig. 1h,i].
Optomap  composite images of the left eye at 1 year after recurrence showing a lightly pigmented fundus with obvious choroidal vessels (a), In a green separation image, a green laser penetrates to the choroid and captures choroidal vessels, including the vortex vein (b), In a red separation image, the red laser penetrates deeper than usual and demonstrates zones of the sclera, while choroidal vessels are obscured (c)
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F2
Composite fundus imaging with the ultra-wide-field Optomap  200Dx system (Optos, Dunfermline, Scotland, UK) at 1 year after recurrence revealed a characteristic "sunset glow" fundus with a clearly visible array of choroidal vessels [Fig. 2a]. In green (523 nm) laser separation imaging, retinal and choroidal vessels, including vortex veins, were clearly observed [Fig. 2b]. The red (633 nm) separation view appeared to penetrate deeper and demonstrated zones of sclera, but the choroidal vessels were obscured [Fig. 2c].