PMC6330526_01
Proliferation of fibrous and muscular tissue showing the presence of spindle-shaped cells with eosinophilic cytoplasm (H&E stain, x40).
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Histological structure of biopsy material was represented by the fibrous and muscular bundles with the presence of spindle-shaped cells with eosinophilic cytoplasm (figure 1).
The microphotograph depicts a high level of vimentin cytoplasmic expression (vimentin, x100).
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IHC study revealed a high level of cytoplasmic expression of vimentin (figure 2) and SMA (figure 3), which is an indicator of tumor growth of mesenchymal origin, in particular, of smooth muscle cells.
The microphotograph depicts a high level of smooth muscle actin cytoplasmic expression (smooth muscle actin, x100).
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IHC study revealed a high level of cytoplasmic expression of vimentin (figure 2) and SMA (figure 3), which is an indicator of tumor growth of mesenchymal origin, in particular, of smooth muscle cells.
The microphotograph depicts a high level of progesterone receptors intranuclear expression (progesterone receptors, x250).
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Also, there was a high expression of progesterone receptors (from 80% to 92%) (figure 4) and a low expression of estrogen receptors (from 30% to 42%) (figure 5).
A low level of estrogen receptors intranuclear expression is revealed (estrogen receptors, x250).
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Also, there was a high expression of progesterone receptors (from 80% to 92%) (figure 4) and a low expression of estrogen receptors (from 30% to 42%) (figure 5).
Low proliferative activity (Ki67) is revealed (Ki67, x40).
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In this case, the level of Ki67 expression was low and accounted for only 5% to 8% (figure 6). 