PMC5813673_01
Total and free concentrations of ropivacaine just before, 30 min, and 11 h after lipid rescue. The concentrations at these time points were 540.6, 617.7, and 159.9 ng/mL (total) and 66, 94.5, and 11.6 ng/nL, respectively (free). The free fraction ratio (free/total) of ropivacaine increased from 12.2 before lipid rescue to 15.3 after lipid rescue
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Fig1
Both the total and free concentrations, and the free fraction ratio of ropivacaine, were higher in 30 min after lipid rescue than before lipid rescue (Fig. 1).