PMC10436321_01
The results of PET-CT: splenic medulla (A) and ascending aorta (B).
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An intensive uptake of the splenic medulla (Figure 1A) and a periprosthetic uptake at the level of the ascending aorta (Figure 1B) were found, compatible with a reactive-infectious condition and/or hematological disease.
Persistent high titers of phases I and II IgG in patient's serum after 3-year follow-up. Phases I and II antibodies were determined by ImmunoFluorescence Assays (IFA) on the patient's serum tested at different dilutions. Images were acquired using a fluorescence high-resolution Microscopy Olympus DP71 with a 40x objective and the analySIS image processing software.
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I and phase II IgG while the phase II IgM titer showed a decreasing trend up to a negative result. In particular, phase I and II IgG titers showed an oscillatory trend over time probably due to the effects of long-term antibiotic therapy (Figure 2 and Table 2).