PMC7774333_01
Preoperative positron emission tomography/computed tomography (PET-CT) of the caudal vertebra and histological features of the chordoma. Coronal section (A) and median sagittal section (B) of the PET-CT in chordoma. Pathologic findings from the initial surgical resection specimen (C, D, HE x400).
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Positron emission tomography/computed tomography (PET-CT) imaging revealed slight distension of and a concentration of radiation in his coccyx 1 (S1) vertebra ( Figures 1A, B ). A surgical specimen obtained from the S1 vertebra was pathologically diagnosed as chordoma ( Figures 1C, D ).
Computed tomography (CT) of the chest. CT scans showing the chest (A, B) before immunotherapy and 4 month(s) after the initiation of immunotherapy treatment (C, D), demonstrating a partial response.
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After 4 months of treatment, the patient exhibited an obvious reduction in the number of metastatic nodules and achieved a partial response (PR) (evaluated by the modified Response Evaluation Criteria in Solid Tumors [iRECIST] for immunotherapy trials, which defines PR as a reduction of more than 30% in tumor load) ( Figure 2 ).