PMC10437099_01
(A and B) Typical AD lesions on both lower extremities and trunk.
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The patient's severity of atopic dermatitis score was 80.2 (mild: 0-24; moderate: 25-50; and severe >50) (Figures 1 and 2).
(A and B) White pustules on the lower extremities and trunk (red arrow in (A and B)).
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The patient's severity of atopic dermatitis score was 80.2 (mild: 0-24; moderate: 25-50; and severe >50) (Figures 1 and 2).
Anatomopathological examination of white pustules revealed epidermal hyperkeratosis with fused dyskeratosis, neutrophilic microabscesses in the dyskeratotic stratum corneum, reduced or even absent granular layer beneath the dyskeratosis, hypertrophy of the spinous layer, upwardly displaced dermal papillae, dilated capillaries, superficial perivascular lymphocytes, and scattered neutrophil infiltration (HEx40).
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The biopsy results suggested epidermal hyperkeratosis with fused dyskeratosis, neutrophilic microabscesses in the dyskeratotic stratum corneum, reduced or even absent granular layer beneath the dyskeratosis, hypertrophy of the spinous layer, upwardly displaced dermal papillae, dilated capillaries, superficial perivascular lymphocytes, and scattered neutrophil infiltration (Figure 3).