PMC5941754_01
Initial intraoral photograph (age: 4 months).
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Her parents reported, during the first months of life, the spontaneous formation of a pink oblong vesicle in the left internal part of the lower lip (Figure 1).
PMC5941754_02
Intraoral photograph (age: 6 months).
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After a month, the patient returned, and the lesion had a significant growth with a shape modification and appeared as a more regular bulla (Figure 2).
PMC5941754_03
Laser-assisted lesion excision (age: 6 months).
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The tip was directed at an angle of 10 to 15 , moving around the base of the lesion with a circular motion (Figure 3).
Intraoral photograph immediately after intervention.
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The diode laser provided a combination of clean cutting of the tissue and hemostasis (Figure 4).
PMC5941754_04
Healing (age: 6.5 months).
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After 2 weeks follow-up (Figure 5), the intraoral wound healed without complications and no signs of infection or mass recurrence were noted.
Follow-up (age: 10 months).
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After 4 months (Figure 6) follow-up, the lesion healed completely and the patient had a functionally and developmentally normal mucosa without lesion recurrence.
The lesion measured about 1 cm maximal length, displayed a polypoid fashion, and was covered by a smooth mucosal layer.
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fig7
Grossly, the lesion displayed a polypoid fashion and was covered by a smooth mucosal layer (Figure 7).
Histologic examination revealed a process deep seated within the submucosal connective tissue (HE, x2 magnification).
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fig8
Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).
The lesion consisted of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (HE, x10 magnification).
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fig9
Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).
Extracellular mucin resulted Alcian blue positive (Alcian-PAS, x20 magnification).
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fig10
Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).