PMC4458002_01
a On magnetic resonance imaging, an heterogeneous multinodular mass was observed on sagittal T1-weighted images (TR/TE: 1,200/120). Dark signal nodules, compatible with hemosiderin deposition, were identified. b On macroscopy a multinodular lesion was evident in the leg and in the thigh showing variegated colour. c, d On haematoxylin and eosin staining the lesion showed synovial-like mononuclear cells without cytologic atypia, admixed with multinucleate giant cells.
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Fig1
In T1-weighted images, dark signal nodules, compatible with hemosiderin deposition, were readily identified (Figure 1a). Alternation of white, yellowish and brownish areas with hematic-cystic lesions was seen (Figure 1b). In particular, the lesion showed synovial-like mononuclear cells lacking significant cytologic atypia, admixed with multinucleated giant cells (Figure 1c, d).
a, b The haematoxylin and eosin staining of the inguinal lymph node revealed a metastasis of D-TGCT showing a proliferation of synovial-like mononuclear cells, admixed with multinucleate giant cells and siderophages.
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Fig2
During surgical procedure frozen examination of one inguinal lymph node was performed that showed a sub-capsular proliferation of mononucleated cells, associated with multinucleated giant cells and siderophages consistent with lymph node seeding of D-TGCT (Figure 2a, b).