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Liver explant pathology of HAV-ALF: all four patients presented similar histological changes. H&E stain shows massive hepatocellular necrosis with prominent lymphoplasmacytic inflammatory infiltration in (a-d) (magnification x20).
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All explants were remarkably similar histologically, showing acute hepatitis with massive hepatic necrosis accompanied by a prominent lymphoplasmacytic inflammatory infiltrate and bile ductular proliferation (see Figures 1(a)-1(d)).