PMC4921155_01
Fetal sonogram shows muscle atrophy (sarcopenia) of right leg. A, fetal ankle; K, fetal knee.
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Fetal sonogram demonstrates absence of sacrum (arrow).
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Fig. 2). US also showed atypical position of legs and feet and sacral defects (Fig. 3, Fig. 4). Fetal MRI confirmed these findings (Fig. 5, Fig. 6) and, in addition, showed a dysmorphic conus medullaris that was both short and nontapered (Fig. 7, Fig. 8).
MRI shows normal size of fetal forearm (black chevron) and sarcopenia of leg (white arrow).
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Fig. 2). US also showed atypical position of legs and feet and sacral defects (Fig. 3, Fig. 4). Fetal MRI confirmed these findings (Fig. 5, Fig. 6) and, in addition, showed a dysmorphic conus medullaris that was both short and nontapered (Fig. 7, Fig. 8).
Box inset of fetal MRI is magnified to demonstrate short and blunted terminus of conus medullaris.
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Fig. 2). US also showed atypical position of legs and feet and sacral defects (Fig. 3, Fig. 4). Fetal MRI confirmed these findings (Fig. 5, Fig. 6) and, in addition, showed a dysmorphic conus medullaris that was both short and nontapered (Fig. 7, Fig. 8).
Transverse US image at 22 weeks gestation age shows normal fetal brain and calvarium. There is no "lemon sign" (flattened or inwardly scalloped frontal bones) or "banana sign" (absent cisterna magna), and other images demonstrated normal ventricular size.
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The remainder of the cord and the brain (Fig. 9) were normal, as were the fetal lungs, liver, and kidneys.
Sagittal T1-weighted MRI of lower neonatal spine shows dysmorphic conus medullaris and absence of sacrum and coccyx. (TSE T1, TR, 601; TE 12)
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Postnatal radiographs confirmed initial in utero findings of dysmorphic conus medullaris (Fig. 10, Fig. 11) and absence of the sacrum (Fig. 12).
Frontal radiograph of neonatal pelvis demonstrates absence of sacrum and coccyx.
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Postnatal radiographs confirmed initial in utero findings of dysmorphic conus medullaris (Fig. 10, Fig. 11) and absence of the sacrum (Fig. 12).