PMC8621997_01
Image of 18F-DOPA PET/computed tomography (CT) of patient. Image demonstrates an asymmetric dopaminergic deficit (worse on the right side) suggestive of Parkinson's Disease.
tohm-11-1-664-g1.jpg
PMC8621997_01_tohm-11-1-664-g1.jpg
F1
Tone was normal but mild bradykinesia was found on the left side, with reduced arm swing while walking. 18F-DOPA PET/computed tomography (CT) showed educed uptake in the right putamen (Figure 1) in keeping with a diagnosis of early-stage Parkinson's disease and she was commenced on levodopa/benserazide.
Drug-induced Alopecia Areata after A) Levodopa, B) Propranolol, and C) Topiramate.
tohm-11-1-664-g2.jpg
PMC8621997_01_tohm-11-1-664-g2.jpg
F2
Four weeks later, on a dose of 100/25 mg three times a day, she called in panic because of sudden severe hair loss on the right back of her head (see Figure 2a). Initially, she reported an 50% improvement of tremulous movements, however, on a dose of 40 mg per day, she developed significant patchy hair loss again (see Figure 2b), causing us to cease the beta-blocking agent. Unfortunately, within less than two weeks the patient noticed first signs of alopecia on the back side of the scalp (see Figure 2c) and after termination of topiramate, regrowth occurred once more after a couple of weeks.