PMC7289613_01
Imaging exams highlighting the injury of the patient. (A): Axial contrast-enhanced CT scan showing neoplastic lesion with an epicentre on the skullcap of the right temporo-occipital transition with intracranial and extracranial expansion. (B): Sagittal contrast-enhanced CT scan showing the same lesion. (C): Magnetic resonance imaging shows a highly enhancing tumour with epicentre in the right side of the posterior cranial fossa. (D): Computerizsd tomography 3 years after the last surgery, the patient accompanied only with chemotherapy and radiotherapy.
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figure1
In the middle cranial fossa, the component was rectifying the turns of the posterior aspect of the anterior temporal pole on this side (Figure 1C). After 3 years, control imaging exams revealed signs of supratentorial and infratentorial leptomeningeal impregnation, suggesting a postoperative scar (Figure 1D).
Anatomopathological and immunohistochemical findings. (A): Hematoxylin and eosin stains show neoplasm with a biphasic pattern characterised by pseudoglandular hyperchromatic cells associated with dense fibrovascular stroma. (B): Synaptophysin was positive in immunohistochemistry. (C): Focal Positivity for gp100 Antigen in Immunohistochemistry.
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figure2
The histopathology of the tissue revealed a biphasic tumour tangential to the resection margins, characterised by small, round and blue cells, as well as pseudoglandular arrangement with pigmented cells infiltrating the bone and muscle tissue (Figure 2A). The immunohistochemical study presented expression of Ki-67, synaptophysin (Figure 2B), product of the INI-1 gene and 40, 48, 50 and 50.6 kDa cytokeratin, being the antigen gp100 focally positive (Figure 2C).