PMC10076646_01
Abdominal CT scan showing a 5 cm lesion on segment 3.
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F1
AdCC metastasis; a subsequent MRI confirmed the previous radiological findings (Figure 1). A percutaneous biopsy of the nodule was performed, and AdCC hepatic localization was diagnosed.
Intraoperative findings: (A-C) shows a single adCC liver metastasis located in the left lobe; (B-D): enhanced liver nodule using ICG; (E-F): combination of US and ICG fluorescence imaging in order to improve mass and margin visualization.
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F2
When the camera was switched to the fluorescence setting, a perilesional tracer diffusion (rim pattern) was clearly seen around the lesion, no other nodules were found (Figure 2).
Histologic features of adenoid cystic carcinoma. Adenoid cystic carcinoma exhibiting predominantly cribriform (A) and tubular (B) growth patterns (hematoxylin and eosin stain, magnification 200x). Myxoid and hyalinized basement membrane material is noted in the cribriform area while tubular pattern contains simple tubules composed of inner ductal and outer myoepithelial cells. Perineural invasion is frequent (C, hematoxylin and eosin stain, magnification 400x). P63 immunostain highlights myoepithelial component and cribriform architecture (D, p63 magnification 400x).
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F3
Scattered areas with cribriform pattern, composed of predominantly myoepithelial cells with myxoid or hyalinized globules, were observed (Figure 3).