PMC9037849_01
CT scan showed a hypodense and unilocular cyst in the tail of the pancreas, with no internal septation or calcification (A - plain, B - arterial phase, C - delayed phase, D - coronal section of delayed phase).
autopsy-12-e2021369-g01.jpg
PMC9037849_01_autopsy-12-e2021369-g01.jpg
gf01
The pancreatic duct was not dilated (Figure 1).
Endoscopic ultrasound with linear echoendoscope revealed a 1.6x1.5cm thinly septated cystic lesion at the pancreatic tail (A), with a suspicious 5mm mural nodule (B).
autopsy-12-e2021369-g02.jpg
PMC9037849_01_autopsy-12-e2021369-g02.jpg
gf02
There was a thin septum within the cyst and a suspicious 5mm mural nodule (Figure 2).
Photomicrographs of the cystic pancreatic lesion. 4A to 4D. H&E sections show cyst lining composed of bland, non-keratinizing squamous epithelium with adjacent splenic tissue (A and B - 100x; C and D - 200x).
autopsy-12-e2021369-g04.jpg
PMC9037849_01_autopsy-12-e2021369-g04.jpg
gf04
Surrounding the cyst was a rim of splenic tissue, featuring typical white and red pulp (Figures 33D and Figure 4).
Photomicrographs of the cystic pancreatic lesion. Immunostainings show co-expression of A - ERG and B - CD68 of the littoral cells in splenic tissue (100x); positivity for (C) p63 and (D) CEA in the squamous cells (200x).
autopsy-12-e2021369-g05.jpg
PMC9037849_01_autopsy-12-e2021369-g05.jpg
gf05
The squamous epithelium was positive for p63 and CEA (Figure 5).