PMC5949673_01
Endoscopic and pathological findings in a patient with cap polyposis. (A) Endoscopic images in a patient with cap polyposis before antibiotic treatment (before ABx). Multiple sessile polyps are observed in the descending colon prior to the initiation of antibiotic treatment. Top and bottom panels show white light endoscopy and chromoendoscopy images, respectively. The polyps appear reddish in color and are covered by white mucus. (B) Microscopic pictures of a patient with cap polyposis. Endoscopic mucosal resection was performed to obtain a histopathological diagnosis. Low magnification revealed inflammatory polyps covered with granulation tissue and fibrinopurulent exudate. Distorted glands were also seen in lamina propria. Hematoxylin and eosin (H&E) staining. Magnification x40.(C) Endoscopic images obtained from a patient with cap polyposis treated with antibiotics (after ABx). Most of the inflammatory polyps are observed to have disappeared 6 months post-antibiotic treatment.
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F1
Colonoscopic examination revealed multiple sessile polyps in the descending colon, which showed a reddish surface covered by white mucus (Figure 1A).Esophagogastroduodenoscopic examination revealed multiple fundic gland polyps. The resected specimen showed mucus-containing distorted glands and significant inflammatory cell infiltration with fibrosis in the lamina propria (Figure 1B) and their surface was covered by inflammatory granulation tissue and fibrinopurulent exudate. Based on this hypothesis, this patient was treated with oral administration of ampicillin (1,500 mg/day) and metronidazole (500 mg/day) for 1 week, and regression of cap polyposis was observed 6 months post-antibiotic treatment (Figure 1C).