PMC2648635_01
Cellular
lobules and nests with poorly developed tubules (HEx200).
JO2008-619637.001.jpg
PMC2648635_01_JO2008-619637.001.jpg
fig1
The cut surface was composed of pale yellow-grey soft tissue with foci of haemorrhage.  The tumor was limited to mesentery without extension to the ileal wall.  Microscopic examination revealed cellular lobules with nests and poorly developed tubules of Sertoli cells (Figure 1) that showed moderate atypia and mitotic figures that average 5-10 per high-power field (Figure 2).
Sertoli cells with moderate atypia and mitotic figures (HEx200).
JO2008-619637.002.jpg
PMC2648635_01_JO2008-619637.002.jpg
fig2
The cut surface was composed of pale yellow-grey soft tissue with foci of haemorrhage.  The tumor was limited to mesentery without extension to the ileal wall.  Microscopic examination revealed cellular lobules with nests and poorly developed tubules of Sertoli cells (Figure 1) that showed moderate atypia and mitotic figures that average 5-10 per high-power field (Figure 2).
Leydig cells surrounded tumor lobules (HEx400).
JO2008-619637.003.jpg
PMC2648635_01_JO2008-619637.003.jpg
fig3
Leydig cells are found at the periphery of the cellular lobules (Figure 3).
Tumor
cells immunoreactive to anti-inhibin (IHCx400).
JO2008-619637.004.jpg
PMC2648635_01_JO2008-619637.004.jpg
fig4
By immunohistochemistry, the neoplastic cells showed positive staining for antibodies against inhibin (Figure 4) and vimentin.