PMC5466596_01
Chest radiographs in anteroposterior incidence shows a diffuse symmetric lesion with confluence of dense micronodular infiltrate, especially middle and lower zones of both lungs.
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His chest X-ray (Fig. 1) was suggestive of extensive interstitial bilateral lung disease and the differential diagnosis was suggested to be either a microlithiasis or an atypical infection.
A high resolution computed tomography (HRCT) of the chest revealing innumerable calcifications throughout the parenchyma, ground-glass opacities, subpleural cystic changes and calcified interlobular septa.
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A high resolution computed tomography (HRCT) (Fig. 2) of the chest was performed and revealed several calcifications throughout the parenchyma, ground-glass opacities, sub-pleural cystic changes and calcified interlobular septa.
Pulmonary alveolar microlithiasis (H&E x12.5 Magnification) Lung parenchyma showing numerous calcified bodies within alveolar air spaces. Subpleural and interstitial fibrosis is also seen.
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The alveolar spaces were filled with numerous calcified bodies which showed concentric lamination and radial striations (Fig. 3, Fig. 4).
Pulmonary alveolar microlithiasis (H&E x50 Magnification) Microlith deposition within areas of fibrosis with patchy chronic inflammation.
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Microliths were also present within the areas of fibrosis (Fig. 5, Fig. 6).