PMC5403006_01
Comparison of fundus and spectral-domain optical coherence tomography images before and after intravenous injection of ranimizumab (IVR) as an adjunct to anti-TB therapy.. Notes: (A) Fundus findings and macula edema associated with CRVO were observed before IVR and anti-TB therapy. (B) CRVO and macular edema were significantly improved after two sessions of IVR.. Abbreviations: CRVO, central retinal vascular occlusion; IVR, injection of ranimizumab; TB, tuberculosis.
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Vascular tortuosity associated with CRVO was observed in the right eye, and BCVA decreased to 2/200 due to ME and hemorrhage (Figure 1A). After two IVR sessions, fundus findings associated with CRVO improved markedly, and ME was resolved except for persistent serous retinal detachment (Figure 1B).
Comparison of fundus and spectral-domain optical coherence tomography images before and after vitrectomy with retinal panretinal photocoagulation.. Notes: (A) Before vitrectomy, retinal hemorrhage in the nasal inferior side with vitreous hemorrhage and relapse of macular edema was detected. (B) After two sessions of vitrectomy with panretinal photocoagulation, retinal hemorrhage and macular edema were resolved, but damage of retinal outer layers in the macula was present.
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However, before the fourth IVR session, severe retinal hemorrhage on the nasal side and VH were found in the right eye, with exacerbation of ME (Figure 2A). However, BCVA remains at 20/200 due to disruption of retinal outer layers in the macula besides retinal ischemic region presented by hyperreflective image in retinal inner layers (Figure 2B).