PMC5929396_01
a) Uterus and cervix measuring 10x6x3 cm.Left ovary is enlarged and measuring 27x17x12 cm. The ovarian capsule is intact and external surface was bosselated.
ijp-13-099-g001.jpg
PMC5929396_01_ijp-13-099-g001.jpg
F1
The ovarian capsule was intact and external surface was bosselated (Figure 1a). Intervening solid grey-white areas had variegated appearance with yellowish friable necrotic areas; at places, there were dark brown hemorrhagic areas along with foci of shiny mucoid areas (Figure 1b).
a)Tumor cells arranged in solid nests and focally forming rosettes along with large central areas of necrosis within the nests (H&E,100X).
ijp-13-099-g002.jpg
PMC5929396_01_ijp-13-099-g002.jpg
F2
Microscopically, the tumor cells were arranged in solid nests and focally forming rosettes along with large central areas of necrosis within the nests (Figure 2a). The tumor cells were small with high nucleocytoplasmic ratio mildly pleomorphic nuclei, granular chromatin, inconspicuous nucleoli, and scant cytoplasm (Figure 2b).
Immunohistochemically profile of tumor cells: Pan CK, NSE;synaptophysin: strongly positive; chromogranin: focally positive
ijp-13-099-g003.jpg
PMC5929396_01_ijp-13-099-g003.jpg
F3
Present case showed positivity for Pan CK, synaptophysin, NSE, and EMA, and focal positivity for chromogranin (Figure 3). 