PMC8757380_01
Immunohistochemical staining of a biopsied lymph node with regressive lumps showing diffusely positive CD3+CD57+CD5+NK cells and numerous reactive CD4 positive T cells demonstrating a high proliferation index, and sparse EBER positive cells.
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PMC8757380_01_fped-09-798959-g0001.jpg
F1
Further monitoring of the patient's hematological parameters by a specialist in pediatric hematology/oncology for the next almost 3 years in ambulatory care revealed persistent splenomegaly and lymphadenopathy with pancytopenia (Supplementary Figure 1).
PMC8757380_02