PMC5963481_01
The top two images are from July 2014, and bottom two images are from October 2014 after 3 months of treatment with temsirolimus.. Notes: There was a significant decrease in the size of the right upper lobe mass which abuts the major fissure. There was also marked improvement in the airspace consolidation involving the right lower lobe. Minimal amount of interstitial thickening remained within the right lower lobe. There was significant improvement in right pleural disease. There is no significant pleural effusion. A 1 cm right upper lobe pulmonary nodule had decreased in size. No significant mediastinal, axillary, or hilar lymphadenopathy was observed. No pericardial effusion was seen. Tiny nodules previously noted in the left lower lobe decreased in size.
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Although her radiologic response was not formally evaluated by RECIST criteria, it was analogous to a robust partial response with significant reduction of a right lung mass and reduction of a pleural mass (Figure 1).