PMC5576236_01
Gross examination: cut off surface of angiosarcoma lumpectomy
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Fig1
After a multidisciplinary reassessment, the patient benefited from a conservative treatment by an enlarged excision of the tumour (Fig. 1).
Micrography showing vascular proliferation dissecting the mesenchymal breast tissue (x10)
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Fig2
The histopathological examination of the surgical specimen found an infiltrating mesenchymal proliferation made of vessels of variable sizes anastomosed to vascular slits with lesional limits (Fig. 2).
Micrography showing a papillary pattern of the angiosarcoma with high nuclear pleomorphism
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Fig3
The endothelial cells were often spindle shaped, with anisocaryotic nuclei and numerous mitoses and reduced cytoplasm (Fig. 3).
Immunohistochemical profile of our case
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Fig4
The immunohistochemical examination on the surgical specimen showed to the same phenotypic profile on biopsy (Fig. 4).