PMC10008024_01
Chromosome banding of the patient showed balanced translocation 46X,t(X:1)(q22;q21) without the Y chromosome.
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Her karyotyping was balanced translocation, 46X,t(X:1)(q22;q21) (Figure 1).
Preoperative pelvic magnetic resonance imaging revealed an 18-cm bifurcated mass with high signal intensity on T2-weighted imaging.
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The tumor had a high signal on T2-weighted imaging (Figure 2), low signal on T1-weighted imaging, and decreased diffusing capacity on diffusion-weighted imaging.
A small uterus and 18-cm solid tumor in the left ovary were detected intraoperatively. The right fallopian tube was normal, but the right ovary was not detected.
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A small uterus and 18-cm solid tumor of the left ovary were detected during the operation (Figure 3).
Histopathological diagnosis was dysgerminoma in the left ovary. Large round cells proliferated like a solid nest with lymphocytic infiltration in the stroma. The cell borders were clear and round with enlarged nuclei, clear cytoplasm, and coarse chromatin staining.
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The histopathological diagnosis of the left ovarian tumor was dysgerminoma (Figure 4), International Federation of Gynecology and Obstetrics (FIGO) stage IIIA1, pT3aN0M0 (positive ascites cytology and metastasis of the greater omentum).
The ovarian tumor was stained strongly with c-kit.
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The removed ovarian tumor specimen was strongly positive when stained for c-kit (Figure 5).