PMC3985194_01
H&E stain. Skin with infiltrate of mast cells in the deep dermis.
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On microscopic examination, the mass was composed of a dense monomorphic infiltrate of tumor cells in the dermis and subcutaneous tissue (Figure 1).
H&E stain. Mast cells with pale blue cytoplasm and round to oval nuclei.
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Cells were medium sized with regular nuclear contours and abundant pale blue cytoplasm (Figure 2).
Toluidine blue stain. Mast cells with purple metachromatic granules in the cytoplasm.
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Toluidine blue stain (Figure 3) and purple on Giemsa stain. The infiltrating cells were CD117 positive on immunohistochemistry (Figure 4).
CD 117 IHC. Membrane staining of mast cells.
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Toluidine blue stain (Figure 3) and purple on Giemsa stain. The infiltrating cells were CD117 positive on immunohistochemistry (Figure 4).