PMC8426030_01
Pre-op MRI Brain, T2W coronal section showing a well-defined lobulated hyperintense mass lesion in atrium of the right lateral ventricle causing mass effect in form of dilated occipital horn of right lateral ventricle.
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figure1
MRI brain showed a well-defined lobulated T1 hypointense, T2 heterogeneously hyperintense mass lesion of size 3.5x3.7x3.6 cm in atrium of the right lateral ventricle causing mass effect in form of dilated occipital and temporal horns of right lateral ventricle and midline shift of 11 mm towards left (Figure 1). Moderate perifocal oedema and homogenous intense enhancement on contrast administration were noted.
Post-op MRI Brain, T1W axial section showing a well-defined lobulated non-enhancing cystic lesion in right parietal lobe communicating with right lateral ventricle with dilated occipital horn.
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MRI brain showed a well-defined lobulated non-enhancing cystic lesion of CSF intensity on all sequences in right parietal lobe communicating with right lateral ventricle with dilated temporal and occipital horn (Figure 2).
(a): Haematoxylin and eosin (H&E) stained sections showing tumour cells arranged in cords in abundant myxoid stroma. The tumour cells have ovoid nuclei and specked chromatin and moderate bipolar cytoplasm. (H&E 400x) IHC revealed tumour cells to be positive for (b): vimentin and (c): CD99, while (d): GFAP, (e): S100, CD34 and Pancytokeratin (not shown) were negative and (f): Ki-67 proliferation index was low, 1%-2%.
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S100 were negative and Ki67 proliferation index was low (1%-2%) (Figure 3). Subsequently fluorescent in-situ hybridisation (FISH) for EWS RNA Binding Protein 1 (EWSR1) gene rearrangement was carried out which revealed positive results.