PMC4430154_01
(A, B, C) white matter changes. The first examination, 3 days after the onset of cerebral malaria, shows diffuses hyperintensities on T2, T2- FLAIR-weighted and the SWI sequences images in the centrum semiovale, periventricular, frontal and occipital white matter, and in the cerebellum; (D) with central microhemorrhages in the occipital, frontal and right semiovale centrum white matter lesions on Gradient Echo (T2*) sequence
PAMJ-20-1-g001.jpg
PMC4430154_01_PAMJ-20-1-g001.jpg
F0001
T1-weighted images, before and after contrast injection, and axial fluid-attenuated inversion-recovery (FLAIR) sequences. The MRI showed diffuses hyperintensities on T2, T2- FLAIR-weighted and the SWI sequences images in the centrum semiovale, periventricular, frontal and occipital white matter, and in the cerebellum (Figure 1A, B, C) with central micro hemorrhages in the occipital, frontal and right semiovale centrum white matter lesions on Gradient Echo (T2*) sequence (Figure 1D). There was no enhancement on T1-weighted images. There was also no evidence for dural sinus thrombosis.
(A,B) at follow-up examination, Two week after the onset of illness. In comparison with the first examination, T2-FLAIR images show resolution of cerebellum hyperintensities,and minimal decrease in the size of the lesion of occipital, frontal and right semiovale centrum white matter; (C) the unenhanced microhaemorrhagic lesionson contrast-enhanced T1-weighted images
PAMJ-20-1-g002.jpg
PMC4430154_01_PAMJ-20-1-g002.jpg
F0002
Two weeks after the first examination (day 15), MRI showed disappearance of the cerebellum and periventricular lesions and minimal decrease in the size of the lesion of occipital, frontal and right semiovale centrum white matter (Figure 2A, B). There was a few central enhancement of white matter haemorrhagic lesions on post-contrast T1-weigted images (Figure 2C).