PMC4678697_01
Salivary parenchyma harboring a well-circumscribed, fascicular proliferation of spindle shaped cells (hematoxylin and eosin stain, original magnification x 25)
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Fig1
Histological examination showed intersecting fascicles of spindle cells (Fig. 1) with ample amount of eosinophilic cytoplasm and elongated nuclei with dispersed chromatin.
Tumor cells infiltrating the adjacent parenchyma (hematoxylin and eosin stain, original magnification x 200)
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Fig2
The cells presented high mitotic activity (5 per 10 high-power fields) and foci of severe atypia without necrosis (Fig. 2).
Tumor cells showing mild nuclear atypia with multinucleated giant cells and mitosis (hematoxylin and eosin stain, original magnification x 400)
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Fig3
The adjacent salivary parenchyma was infiltrated by tumoral cells (Fig. 3).
H-caldesmon positivity of the tumor cells (original magnification x 400)
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Fig4
Immunoreactivity with anti smooth muscle actin and H-caldesmon (Fig. 4) antibodies was found.