PMC5438009_01
Left panel: PAM staining showing crescent formation (x400). Right panel: Immunofluorescence demonstrating immunoglobulin A (IgA) deposition (x400).
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Figure1
The biopsy section contained 20 glomeruli: 5 globally-sclerosed glomeruli, 3 with segmental sclerosis, 7 with cellular crescent formation, 2 with fibrocellular crescent formation, and 3 with mesangial hypercellularity with IgA and C3 deposition (Figure 1).
PAM staining showing thrombi (arrowheads) in the periglomerular capillary tuft and vascular pole (x400).
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Figure2
Some glomeruli revealed evidence of progressive thrombotic microangiopathy (TMA) with excessive neutrophil infiltrates, capillary loop occlusions, abnormal capillary loop thickening, and thrombi filling portions of the peri-glomerular capillary tuft and vascular pole (Figure 2).