PMC4132601_01
Computed tomography: transversal view of a 9-cm tumor in the upper pole of the left kidney.
CEJU-67-00355-g001.jpg
PMC4132601_01_CEJU-67-00355-g001.jpg
F0001
A computed tomography scan (Figure 1) revealed a 9-cm tumor of the upper pole of the left kidney with suspected infiltration of the adrenal gland, renal fascia, left renal vein, and artery.
HE-morphology and immunohistochemical analysis of the paraganglioma A Normal renal parenchyma on the left hand side and paraganglioma on the right hand side are separated by a thick layer of connective tissue (HE, 20x magnification). B The paraganglioma (right) shows no positivity for cytokeratin (CK) in contrast to the renal tubules (left) (20x magnification). C HE-morphological assessment revealed a tumor grown in trabecules with relatively monomorphous tumour cells (100 x magnification). D Immunohistochemistry against the S100 protein demarks a layer of sustenticular cells (200x magnification). E The majority of tumour cells is positive for synaptophysin (200x magnification).
CEJU-67-00355-g002.jpg
PMC4132601_01_CEJU-67-00355-g002.jpg
F0002
Histological and immunohistochemical analysis revealed a 6 cm, partially necrotic, extra-adrenal phaeochromocytoma in the area of the renal hilus with marked blood vessel invasion, spreading directly to the kidney and adrenal gland, but not infiltrating them (Figure 2).
F-18-DOPA PET-CT: 3-axial view of the F-DOPA positive, recurrent tumor in the left paraaortal region with a maximum diameter of 5 cm. A: CT, B: PET-CT, C: DOPA-CT.
CEJU-67-00355-g003.jpg
PMC4132601_01_CEJU-67-00355-g003.jpg
F0003
A 3.5 x 5 cm second tumor was detected paraaortalally to the left with possible infiltration of the pancreas and spleen (Figure 3).