PMC3505941_01
Histologic and immunohistochemical findings of the recurrent tumor.
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fig1
Immunohistochemical analysis of a tumor specimen taken from the second surgery demonstrated diffuse positive staining for gross cystic disease fluid protein 15 (GCDFP-15) as an antibody specific with EMPD and also strongly positive (3+) staining for human epidermal growth factor receptor protein 2 (HER2) (Figure 1).
CT image of the metastatic lesion.
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fig2
Following the tenth infusion, a near-complete response was achieved with the only residual disease being a 3 mm, scar-like shadow in the left lung (Figure 2).