PMC9577112_01
(A) Sagittal T2-weighted MRI shows three large lesions at the T7-T11 level with low signal intensity. The lesions shown with a dural tail sign. (B,C) The sagittal CT scan shows that there are five different sizes of high-density masses at the T7-T8 (D), T8-T9 (E), T10-T11 (F), and T11-T12 (G), levels, and all of them are located at the posterior of the spinal canal.
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F1
Magnetic resonance imaging (MRI) revealed multiple intradural extramedullary tumors at the T7-T11 level compressing the spinal cord (Figure 1A). T7-T12 level, and the dural sac was significantly compressed (Figures 1B,C). Three large high-density masses (13.4 mm*8.4 mm, 21.7 mm*13.0 mm, and 14.9 mm*12.5 mm) were observed in the T7-T9 segment, located in the dorsal left rear spinal cord with clear boundaries and ossification signals (Figures 1D-F). The other two high-density masses (8.7 mm*5.3 mm and 11.1 mm*6.73 mm) of different sizes were found in the T10-T12 segment.
(A) Tumors are demonstrated to be a spinal meningioma on histology (H/E stain, original magnification x100). (B,C) Psammoma bodies around the tumor cells. Mature bone tissues around the tumor cells, including trabecular bone, as well as bone marrow with hematopoiesis (H/E stain, original magnification x40). Immunohistochemically, the neoplastic meningothelial cells are immunoreactive for (D) epithelial membrane antigen (EMA) (x10), (E) vimentin (x10), and (F) soluble protein-100 (S-100) (x10).
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In addition, there were many mature bone tissues around the tumor cells, including trabecular bone, as well as bone marrow with hematopoiesis (Figures 2A-C). Immunohistochemical findings revealed EMA (+), Vim (+), P53 (-), S-100 (+), and Ki67 (approximately 5%) (Figures 3D-F).
(A-E) CT scans show a satisfactory decompression of the spinal cord, and no recurrence spinal meningioma was found after 2 years.
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In addition, there were many mature bone tissues around the tumor cells, including trabecular bone, as well as bone marrow with hematopoiesis (Figures 2A-C). Immunohistochemical findings revealed EMA (+), Vim (+), P53 (-), S-100 (+), and Ki67 (approximately 5%) (Figures 3D-F). CT scans showed a total resection of the tumors, and there was no recurrence 2 years after surgery (Figures 3A-E).