PMC6378479_01
(A, C) Kappa immunofluorescence stain in glomerulus and tubular cell protein droplets. (B, D) The corresponding lambda light chain stain is negative.
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Immunofluorescence staining on fresh frozen tissue showed proteinaceous casts and tubular cell protein droplets that stained with kappa (3-4+), whereas it was dim to negative for lambda light chains (Figure 1A to D).
(A, B) H + E-stained sections of the renal biopsy with moderate interstitial fibrosis in the interstitium and accompanying tubular injury with casts and luminal cell exfoliation. (C) Dense lymphoid infiltrate in the bone marrow and (D) CD20 staining on the same lymphoid infiltrate highlighting the B cells.. H + E, hematoxylin and eosin.
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There were no capillary loop double contours, spikes and holes, or hyaline thrombi (figure 2).