PMC3099223_01
Polymorphous dermatosis characterized by disseminated erythematous papules and plaques and multiple brown macules.
CRIM2011-703257.001.jpg
PMC3099223_01_CRIM2011-703257.001.jpg
fig1
Clinical examination revealed numerous generalized symmetrically distributed brownish macules and some pruritic, hyperkeratotic, erythematous papules (Figure 1).
Hematoxylin and eosin. (a) Discrete hyperkeratosis, elongated rete ridges with digitiform projections, and focal acantholysis with formation of linear clefts. Presence of mixed dermal inflammatory infiltrate. (b) Dyskeratotic cells in the interior of a acantholytic cleft. (c) and (d) Digitiform elongation of the rete ridges, with hyperpigmentation of the basal layer confined to the tips of the rete ridges. Suprabasal acantholysis.
CRIM2011-703257.002.jpg
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fig2
Multiple foci of suprabasilar acantholysis were also observed (Figure 2) and a mixed dermal inflammatory infiltrate. In one of the biopsy specimens, we found acantholytic and dyskeratotic cells (Figure 2(b)).