PMC5824514_01
Extraoral profile of the patient is bilaterally symmetrical. No extraoral swelling is seen
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F1
No extraoral swelling was appreciated [Figure 1].
Clinical image shows swelling in the posterior region of the right upper jaw extending from the region of the second premolar to the second molar
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F2
Intraoral examination revealed a painless, round swelling measuring 3 cm x 2 cm on the right palatal aspect extending from the region of the second premolar to the second molar [Figure 2].
Computed tomography shows a large, well-defined expansile lytic lesion involving the right maxillary sinus and the corresponding alveolar arch (white arrow)
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F3
Lateral aspect showed perforation of the maxillary sinus [Figure 3].
Clinical image shows gross resected specimen, white red in color and an irregular surface
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F4
On gross examination, the resected specimen was soft measuring 1.3 cm x 1.5 cm x 0.9 cm, white in color, varying in consistency (with soft to firm areas) and an irregular surface [Figure 4].
Histopathological examination reveals highly cellular connective tissue stroma at low power view (x4)
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F5
Mesenchymal component was highly cellular, exhibited pleomorphism and 1-2 mitotic figures per high power field [Figures 5-8].
Histopathological examination reveals sheet of cells within lacunae (x10)
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F6
Mesenchymal component was highly cellular, exhibited pleomorphism and 1-2 mitotic figures per high power field [Figures 5-8].
Given H&E stained section shows the presence of increased proliferation of chondrocytes within lacunae with increased nuclear atypia (arrow) nuclear hyperchromatism (red arrow) and cellular atypia (arrowhead), inset showing binucleated chondrocytes (arrowhead) (x40)
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F7
Mesenchymal component was highly cellular, exhibited pleomorphism and 1-2 mitotic figures per high power field [Figures 5-8].
Histopathological examination reveals large abnormal chondrocytes exhibiting nuclear pleomorphism (red arrow) and cellular pleomorphism (black arrow) (x40)
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F8
Mesenchymal component was highly cellular, exhibited pleomorphism and 1-2 mitotic figures per high power field [Figures 5-8].