PMC6300854_01
Photographs from cystoscopy: A - the presence of an enterovesical fistula, approximately 3 cm long and 1 cm wide, B - ADRC were injected around the fistula using a needle routinely used for botulin injections, C - control cystoscopies performed 22 days and 13 months after the treatment showed complete resolution of the enterovesical fistula
PG-13-34211-g001.jpg
PMC6300854_01_PG-13-34211-g001.jpg
f0001
During cystoscopy, the suspension was injected around the fistula through an 18 G needle, the size routinely used for botulin injections, in 0.5-ml aliquots into the detrusor muscle (Figure 1).
The acquisition of an MSC phenotype by the ADRC (freshly isolated). A - Typical CDMSC markers as determined by FACS, B - the ADRC phenotype in standard culture
PG-13-34211-g002.jpg
PMC6300854_01_PG-13-34211-g002.jpg
f0002
The obtained ADRC expressed CD73 (99.3% of cells), CD90 (99.6%), and CD105 (89.1%) as well as CD34, CD19, CD11b, and HLA-DR (all in 1.7% of cells) as surface markers (Figure 2).