PMC6854950_01
Purpuric rash on the patient's lower extremities.
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A 35-year-old Japanese man with a history of renal disease presented to a dermatology clinic with sudden onset of a purpuric rash on his lower extremities (Figure 1) and was diagnosed with anaphylactoid purpura.
Mesangial proliferative glomerulonephritis was demonstrated (PAS stain).
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Histopathological examination of renal biopsy specimens revealed mild mesangial proliferation (Figure 2).
Mesangial IgA deposition was observed by immunohistochemistry.
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Immunohistochemical examination revealed mesangial IgA (Figure 3), IgG and C3 (Figure 4) depositions, and he was treated with corticosteroids.
Mesangial C3 deposition was observed.
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Immunohistochemical examination revealed mesangial IgA (Figure 3), IgG and C3 (Figure 4) depositions, and he was treated with corticosteroids.