PMC5579424_01
Frontal view (A) and side views (B,C) in a 32-week pregant patient with gigantomastia. The patient presents with peau d'orange texturing of breasts, ulcerations and dilated veins on the upper thorax
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During her hospitalization, breasts continued to increase in size (bra size passed from fifth to tenth measure),with skin atrophy, necrosis and multiple ulcers measuring 2-5 cm in diameter (Figure 1).
Biopsy of mammary gland with edema, abundant proliferation of stromal loose connective tissue, myxoid degeneration of the stroma, lobular ductal hyperplasia and cystic dilation of breast ducts.
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There was no chronic inflammatory cellular infiltrate and histologic evidence of malignancy (Figure 2).
Postreduction mammoplasty with free nipple graft 2 months after surgery (A) and 12 months after surgery (B)
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The patient was followed for 12 months with no sign of recurrence or breast carcinoma found on physical examination and sonography (Figure 3).