PMC6948309_01
Representative colonoscopy findings in the course. Left: left-sided ischemic colitis; middle: recovery of colitis; right: severe progression of colitis with additional Clostridium difficile infection.
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The next colonoscopy on the 26th June (hd19) revealed a severe progression of ischemia (Figure 1).
LiMAx measurements over time.
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After recovery of liver function was confirmed on 25th July (hd48) with LiMAx (401 microg/kg/h), the dose of caspofungin was increased to 50 mg/d (Figure 2).
Different laboratory parameters over time. INR: International normalized ratio.
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Coagulatory function showed no abnormalities with an INR of 1.02 (Figure 3).
Different laboratory parameters over time. MELD: Model of endstage liver disease-score.
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A second septic crisis occurred on 10-11th July (hd33/34) with elevation of leucocytes up to 47.7/microL, CRP 141 mg/L and relapsing renal failure with the need for hemodialysis (Figure 4).
Various laboratory parameters and LiMAx measured values over time. CRP: C-reactive protein.
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Other parameters of septic shock showed an increase of lactate (2.78 mmol/L) and interleukin 6 (746.1 pg/mL) (Figure 5).