PMC8133855_01
Severe erosions and presence of bullous lesions of the oral mucosa.
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The patient had initially been referred to dermatology after developing bullous lesions and erosions of her oral mucosa and to a lesser degree of her skin (Figure 1).
Oral prednisone dose over time. The arrow represents initiation of rituximab.
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Mycophenolic acid (MPA) was initiated to address both MN and MMP and titrated to reach 1080 mg twice daily, with a progressive tapering of oral glucocorticoids (Figure 2).
Serum albumin over time (top panel) and 24-hour proteinuria over time. The arrow represents infusions of rituximab.
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Initial laboratory follow-up showed reduced proteinuria (Figure 3). On assessment 4 months after starting rituximab, clinical remission was observed, with absence of edema, resolution of cutaneous symptoms, and reduction of proteinuria (Figure 3).