PMC2901615_01
(a) Inflammatory nodules on thighs. (b) Panniculitis with eosinophils infiltration.
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fig1
In November 2007, he consulted for a 1-year history of recurrent, painful nodules with inflammatory signs on his limbs and trunk (Figure 1(a)). The histopathologic study of a cutaneous specimen showed an inflammatory infiltrate predominantly composed by eosinophils that involved both the fat lobules and the septa (Figure 1(b)).
(a) Prurigo-like lesions with central crust mimicking arthropod bites. (b) Interstitial dermal infiltration composed by eosinophils. (c) Flame figures.
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fig2
Examination of skin revealed a widespread eruption consisting of erythematous papules, some with central crust and excoriations (Figure 2(a)). A skin biopsy specimen showed a dense eosinophilic interstitial infiltrate that affected dermis (Figure 2(b)) with occasional "flame figures" (Figure 2(c)), and no changes in subcutaneous tissue were observed.