PMC2840966_01
Bony lamellae surrounded by florid granulomatous inflammation (H and E, x100)
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F0001
Histopatholoical examination showed fragments of partly necrotic bone and diffuse chronic inflammatory cell infiltrate including many giant cells, histiocytes, lymphocytes and plasma cells [Figure 1].
Intracellular inclusions within the giant cells (H and E, x400)
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F0002
Numerous encapsulated yeast forms, a few showing budding were present within the giant cells [Figure 2] and extracellulary within florid granulomatous inflammation [Figure 2].
Intracellular inclusions, few showing narrow base budding (Gomori methamine silver stain, x1000)
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F0003
A Gomori methenamine silver stain and mucicarmine stain highlighted yeast formed with narrow based budding [Figures 3 and 4].
Mucicarmine stain highlighting the extracellular fungal spores (H and E, x400)
JGID-02-63-g004.jpg
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F0004
A Gomori methenamine silver stain and mucicarmine stain highlighted yeast formed with narrow based budding [Figures 3 and 4].