PMC5836202_01
Dense infiltration of spindle-shaped atypical cells with pigmentation from the superficial dermis to the deep dermis (A). Multiple in-transit metastases on the scrotum that are ingrown: before imiquimod treatment (B) and after imiquimod treatment (C).
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F1
A biopsy specimen revealed dense infiltration of spindle-shaped atypical cells with pigmentation from the superficial dermis to the deep dermis (Fig. 1A). Four months after the radiation therapy, multiple in-transit metastases on the scrotum (Fig. 1B) and right external iliac lymph node had developed. Six weeks after we had started to administer topical imiquimod, all in-transit melanoma lesions had disappeared with scaring (Fig. 1C); however, the right external iliac lymph node remained swollen.