PMC5824515_01
Cone-beam computed tomography view shows large ill-defined radiolucency with ragged borders on anterior part of maxilla
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F1
(a) Microscopic features of tumor. Nest of epithelial cells and some clear cells with abundant cytoplasm. (b) Microscopic features of tumor. Atypical mitotic figures in tumoral cells (H & E, x400)
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F2
Microscopic examination showed a neoplastic tissue composed of numerous nest and islands of epithelial cells with plump nuclei and prominent nucleoli and some clear cells with abundant cytoplasm and occasionally duct-like figures [Figure 2a]. Large sheets of necrosis and occasionally atypical mitoses were also seen [Figure 2b].
Positron emission tomographic-computed tomography view. Note numerous hypermetabolic areas in right maxillary sinus and nasal cavity, lungs, hilar regions, left kidney and left retroperitoneal soft tissue
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F3
Immunohistochemical stain for CD10 showing positive reactivity in tumoural cells
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F4
The immunohistochemical staining showed positive immune reactivity for CD10 antigen in some tumoral cells and confirmed the renal cell origin of carcinoma [Figure 4].
PMC5824515_02
Clinical view of the patient shows large exophytic mass
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F5
Microscopic features of tumor. (a)sheets of tumoral cells with large clear cytoplasm. (H & E, x100). (b) hemorrhagic background of tumoral cells. (H & E, x400)
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F6
Sheets of hemorrhage were seen among the tumoral cells [Figure 6b].
Immunohistochemical staining. Positive reactivity for epithelial membrane antigen
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F7
Ki-67 was positive in >=30% of tumoral cells [Figure 7].
Positron emission tomographic-computed tomography view shows some hyper metabolic areas
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F8
FDG-PET-CT scan reported hypermetabolic soft-tissue mass lesion on the left side of the oral cavity with evidence of invasion to the adjacent maxillary bone, left hilar region and multiple randomly distributed pulmonary nodules in the both lungs and left kidney in a heterogeneous mass with a maximum dimension of 4.5 cm [Figure 8].