PMC6748569_01
Taxonomic composition and diversity in 13 induced sputum samples collected from the same patient (chronic obstructive pulmonary disease) at different consultations.. A: Presenting taxonomic composition at level 6 taxonomy (genus), provided by Silva database for amplicon sequence variants containing at least 1% of all sequences. Numbers are given as relative abundances per sample. B: Phylogenetic alpha- and beta-diversity. Alpha-diversity measured by Faith phylogenetic diversity (right y-axis). Non-quantitative and quantitative beta-diversity measured by UniFrac (UWUF, WUF respectively, left y-axis). Except from the first sampling time point beta diversity is calculated between consecutive samples. A+B: Disease state given in A by S = Stable state, E = Exacerbations. Samples are ordered chronologically and collection dates are given in B.
pone.0222449.g009.jpg
PMC6748569_01_pone.0222449.g009.jpg
pone.0222449.g009
The taxonomic composition (including ASVs consisting of >= 1% of all sequences) for each of the 13 samples are shown in Fig 9A.