PMC5881244_01
Macroscopic findings in gastroscopy and colonoscopy. Follicular hyperplasia in upper and lower intestinal tract.
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F1
The endoscopic evaluation macroscopically showed nodular hyperplastic spots particularly in the gastric antrum and terminal ileum (Figure 1).
Immunohistochemical findings demonstrating mature mast cell infiltration. Dense stromal mast cell infiltrations of up to 60/HPF [staining for CD117+ (left), tryptase (right), and CD25- (lower left image)]; mature type; cKIT-D816V mutation negative; normal crypt architecture; no eosinophils.
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F2
Immunhistochemically, up to 60 tissue mast cells per high power field with normal morphology were detected (no immature cell forms or spindle shapes, CD117+, MCT+, CD25-, and c-KIT D816V negative; Figure 2).