PMC9885242_01
a Microscopic photo of the skin of the 18-year old. Suboptimal processed biopsy with incrustation, spongiosis, and scattered necrotic keratinocytes (x100). b Microscopic photo of the skin of the 16-year old. Mild inflammatory changes with a few necrotic keratinocytes and a sparse lymphocytic dermal infiltrate (x150).
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PMC9885242_01_cde-2023-0015-0001-528422_f3.jpg
F3
The biopsy from the 18-year old showed an incrusted spongiosis with focal lichenoid changes with dermally located predominantly eosinophilic but also a few neutrophilic granulocytes (shown in Fig. 3a). The biopsy from the 16-year old showed minimal changes with mild hyperkeratosis, and mild epidermal hyperplasia with few necrotic keratinocytes, and a sparse dermal infiltrate of lymphocytes and a few melanophages (shown in Fig. 3b).