PMC8593452_01
Computed tomography images of taken before the first endobronchial treatment.. (A) Middle trachea, (B) tracheal bifurcation, and (C) liver (liver metastasis).
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However, the patient complained of dyspnea because no reduction of the bronchial lesions was achieved by the chemotherapy (Fig. 1), and therefore, he was referred to our hospital for bronchoscopic intervention.
Bronchoscopic images taken before the first endobronchial treatment.. (A) Upper trachea, (B) middle trachea, (C) right main bronchus, and (D) left main bronchus.
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The tumors had almost completely occluded the right main bronchus (Fig. 2).
Histological findings of the tumor.. Tumor cells were growing in a trabecular and cribriform pattern, and there was some mucus retention. (A) Tumor cells had a polygonal, moderately eosinophilic cytoplasm, and a nucleus with mild atypia. The tumor showed 5 to 10 mitoses per 2 mm2. Immunostaining was positive for chromogranin A and synaptophysin staining, and slightly positive for CD56. (B, C and D) (A) Hematoxylin and eosin staining (magnification: x 100), (B) synaptophysin staining (magnification: x 100), (C) chromogranin staining (magnification: x 100), and (D) CD56 staining (magnification: x 100).
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The resected tumor was diagnosed as atypical carcinoid based on histological findings (Fig. 3).