PMC3888869_01
Timeline for disease presentation and immune therapy. Events as indicated relative to immune therapy start date. The patient received a total of three treatments that consisted of HLA-I upregulation (either intralesional injection of 3 x 106 IU of IFNbeta-Ib or 8 Gy radiotherapy) followed by administration of 1010/m2 MCPyV-specific polyclonal CD8+ T cells and 14 days of twice daily subcutaneous injections of IL-2 (2.5 x 105 IU/m2). XRT: radiotherapy.
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F1
The patient underwent three rounds of treatment (Fig. 1).