PMC7298278_01
Kidney function trends and therapeutic strategies' timeline during hospitalization.
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fig1
To promote a "flushing" effect within tubules, mannitol was given from the 9th of April onwards, with rapid and progressive decrease in sCr (Figure 1).
(A) Extensive tubular injury, partially haemolyzed and/or fragmented red blood cells within tubular lumen (H&E 10x). (B) In light microscopy, 10 glomeruli were identified; two glomeruli with mild expansion of mesangial matrix, minimal segmental endocapillary proliferation, flocculo-capsular adhesion with irregularities of Bowman's capsule, and activation of parietal epithelium; tubular injury (PAS 20x). (C) Tubular injury (H&E 20x). (D) IF stain for IgA with mesangial, vessels walls, and endotubular material staining pattern (20x).
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fig2
Immunofluorescence studies showed 4 + positivity for IgA (Figure 2).