PMC10046706_01
(A) Computed tomography scan showing the mass posterior to the left thyroid lobe with suspicion of esophageal wall involvement. (B) Recurrent laryngeal nerve after thyroid and tumor deflection. (C) Cut surface of the tumor showing an inhomogeneous white-tan appearance.
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Computed tomography (CT) showed a 2.5- x 3.6-cm enhanced mass at the left tracheoesophageal groove with suspicion of esophageal involvement (Figure 1A). The tumor was found after deflection of the left thyroid lobe, and the recurrent laryngeal nerve was successfully preserved (Figure 1B). The cut surface of the tumor showed an inhomogeneous tan-white appearance (Figure 1C).
(A, B) Histopathologic examination of the tumor showed spindle cells with elongated wavy nuclei, a biphasic pattern, and focal nuclear palisading (hematoxylin and eosin, x100). Immunohistochemistry showed positivity for (C) S-100 (x100) and (D) SOX-10 (x100).
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Immunohistochemistry (IHC) was positive for smooth muscle actin, S-100, SOX-10, and caldesmon and negative for CD117, DOG1, CD34, and desmin; these findings were compatible with schwannoma (Figure 2).