PMC10125823_01
Bone marrow biopsy specimen [A, B: Hematoxylin and Eosin staining (x100), respectively; C: Giemsa stain (x100); and D: CD68 antibody stain (x100)]. The bone marrow was normocellular, with a 1:1 cell-to-fat ratio. The arrows show hemophagocytic histiocytes.
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A bone marrow biopsy showed macrophages engulfing blood cells (Fig. 1).
Clinical course of the patient. The horizontal axis corresponds to the hospital days, beginning from day 1. Curves with a shaded area represent the degree of corresponding findings. The top of the curve indicates the point where the maximal finding was observed. The bottom of the curve is where the finding was no longer observable. Laboratory values are shown in the line graphs. Observed values are indicated with dots.
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Serum fibrinogen levels were within normal limits throughout his clinical course (Fig. 2).