PMC3810345_01
Gross image of the uterus and tumor.
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PMC3810345_01_ott-6-1515Fig1.jpg
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The uterus measured 10 x 8 x 5 cm and the cavity was filled with a cauliflower-like tumor measuring 6 x 3 x 2.5 cm and containing areas of ulceration (see Figure 1).
Mixed components: a close transition from the endometrial adenocarcinoma to the yolk sac tumor areas (hematoxylin and eosin, 100x).
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PMC3810345_01_ott-6-1515Fig2.jpg
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Histopathologic examination of the uterine tumor revealed well to moderately differentiated endometrial adenocarcinoma with yolk sac tumor-like differentiation intraendometrially, with a close transition between the two components (Figure 2).
Immunohistochemical staining results for alfa-fetoprotein confirm the existence of two components of endometrial adenocarcinoma and yolk sac tumor.
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PMC3810345_01_ott-6-1515Fig3.jpg
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The yolk sac tumor component was strongly positive for alfa-fetoprotein, while the endometrial adenocarcinoma was relatively negative (Figure 3).