PMC7785811_01
Fundus photography of the left eye showing the presence of a pale optic disc, diffuse arterial narrowing, a mild 'cherry-red spot' macula and peripheral areas of retinal pigmented epithelium hyperpigmentation (A). IR and SD-OCT acquisition over the macular region of the same eye denoting atrophy of the inner retina layers with loss of foveal depression and temporal macular thinning (B,C) [IR, infrared reflectance, SD-OCT, spectral domain optical coherence tomography].
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F1
Right eye ophthalmologic examination was unremarkable, while the left eye showed a nonreactive mydriasis, and dilated fundus ophthalmoscopy revealed the presence of severe arterial narrowing, retinal whitening in the macular region with loss of the physiological macular reflex and peripheral areas of retinal pigment epithelium hyperpigmentation (Figure 1A). Optical coherence tomography (OCT) showed temporal macular thinning in both eyes and severe atrophy of the inner retina layers with loss of the foveal depression in the left eye (Figures 1B,C).
Fluorescein angiography of the left eye 5 days after the diagnosis of CRAO showing a delayed arrival of the dye in the eye 43 s after the injection (A), peripheral areas of capillary nonperfusion, arteriovenous anastomoses, and neovascular 'sea-fans' 4 min and 22 s after the dye injection (B) [CRAO, central retinal artery occlusion].
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F2
In addition, findings consistent with sickle cell retinopathy were remarked, including areas of peripheral capillary nonperfusion, arteriovenous anastomoses, and neovascular "sea-fans" (Figure 2).
Ganglion cell layer thickness analysis performed with the SD-OCT one month after the arterial occlusion. Within normal limits in the right eye (A) and atrophic in the left eye (B) [SD-OCT, spectral domain optical coherence tomography].
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F3
OCT scans confirmed the loss of the foveal depression and showed ganglion cell layer atrophy (Figure 3).