PMC5757112_01
Right-sided dominant thyroid nodule seen on thyroid ultrasonography.
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fig1
Her right nodule remained stable until November 2014, when it was noted to have grown to 3.8 cm (Figure 1).
Mantle cell lymphoma involving the thyroid and prelaryngeal lymph node (insert), stained with Hematoxylin and Eosin (100x).
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A Delphian lymph node excision done at the same time revealed similar involvement by mantle cell lymphoma (Figures 2 and 3).
Mantle cell lymphoma involving the thyroid and prelaryngeal lymph node (insert), stained with Hematoxylin and Eosin (400x).
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fig3
A Delphian lymph node excision done at the same time revealed similar involvement by mantle cell lymphoma (Figures 2 and 3).
Mantle cell lymphoma (100x). Positive staining with CD20.
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Mantle cell lymphoma (100x). Positive staining with CD5.
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fig5
CD5 (Figure 5), CD43 (Figure 6), cyclin D1 (Figure 7), and SOX11 (Figure 8). Cyclin D1 and SOX11 also highlighted scattered interfollicular neoplastic B cells. Concurrent flow cytometric analysis identified CD19+, CD20 bright+, CD5+, and CD10- monoclonal B cells with lambda light chain restriction.
Mantle cell lymphoma involving thyroid (100x). Positive staining with CD43.
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fig6
CD5 (Figure 5), CD43 (Figure 6), cyclin D1 (Figure 7), and SOX11 (Figure 8). Cyclin D1 and SOX11 also highlighted scattered interfollicular neoplastic B cells. Concurrent flow cytometric analysis identified CD19+, CD20 bright+, CD5+, and CD10- monoclonal B cells with lambda light chain restriction.
Mantle cell lymphoma (100x). Positive staining with cyclin D1.
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fig7
CD5 (Figure 5), CD43 (Figure 6), cyclin D1 (Figure 7), and SOX11 (Figure 8). Cyclin D1 and SOX11 also highlighted scattered interfollicular neoplastic B cells. Concurrent flow cytometric analysis identified CD19+, CD20 bright+, CD5+, and CD10- monoclonal B cells with lambda light chain restriction.
Mantle cell lymphoma (100x). Positive staining with SOX 11.
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fig8
CD5 (Figure 5), CD43 (Figure 6), cyclin D1 (Figure 7), and SOX11 (Figure 8). Cyclin D1 and SOX11 also highlighted scattered interfollicular neoplastic B cells. Concurrent flow cytometric analysis identified CD19+, CD20 bright+, CD5+, and CD10- monoclonal B cells with lambda light chain restriction.
Mantle cell lymphoma (100x). Ki67 staining.
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fig9
The Ki-67 index was 10% (Figure 9).