PMC3509421_01
Ultrasonography showed heterogeneous mass with cystic and solid components, measuring 19 x 10 x 11 mm.
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fig1
On sonography the mass was heterogeneous with solid and cystic components, measuring 19 x 10 x 11 mm (Figure 1).
Low power magnification of papillary structures showing multilayer cells covering a fibrovascular stalk (H. E. x100).
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fig2
Permanent sections revealed a dilated duct with papillary structures protruding into the lumen (Figures 2 and 3).
Higher magnification of one of the papillary structures (H. E. x400).
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fig3
Permanent sections revealed a dilated duct with papillary structures protruding into the lumen (Figures 2 and 3).
Multiple papillary structures with one in the center showing a mitotic figure (H. E. x400).
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fig4
These papillary structures had fine fibrovascular cores and were covered with multilayered cells showing prominent nuclear pleomorphism and brisk mitotic activity (Figure 4).
Immunohistochemical SMA stain showing the absence of myoepithelial cell layer in papillary structures (x400).
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fig5
Final diagnosis was "intraductal papillary carcinoma" (Figure 5).