PMC8651386_01
ITP diagnosis and treatment timeline. Major dates in the patient's initial ITP presentation and treatment course occurring in 2019 are listed along the x-axis with accompanying hash marks and events above. Daily platelet counts (/microL) and LDH (U/L) where available are listed below respective dates. The above timeline includes major therapies with which the patient was treated, spanning across dates received including prednisone 1 mg/kg (blue bar), IVIG (red bar), dexamethasone 40 mg (yellow bar), and romiplostim 120 mcg (green bar). Overlapping bars imply multiple treatments given on same days.
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fig1
Despite steroids and 2 additional platelet transfusions over the next two days, his platelets remained 4,000/microL, prompting transfer to our facility for IVIG consideration (Figure 1).
TTP diagnosis and treatment timeline. Major dates in patient's TTP presentation and treatment course occurring in 2020 are listed along the x-axis with accompanying hash marks and events above. The red scale break on the x-axis signifies large relative gap in time between dates. Daily platelet counts (/microL) and LDH (U/L) where available are listed below respective dates. The above timeline includes major therapies with which the patient was treated, spanning across dates received including dexamethasone 40 mg (red bar), prednisone 1 mg/kg (blue bar), and plasma exchange (TPE, green bar). Overlapping bars imply multiple treatments given on same days.
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fig2
Given the high likelihood for TTP, he received urgent plasmapheresis (Figure 2).