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Endoscopic image of a 5 mm-sized polyp of the cecum. (a) Erythematous depressed polyp in the cecum. (b) Narrow-band imaging images of the polyp. (c) Narrow-band imaging magnified image of the polyp.
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As a result, a 5 mm IIa polyp (Figure 1a) was found in the cecum, which had not been identified a year earlier. The findings of narrow-band imaging (Figure 1b,c) were different from these of adenoma.
Hematoxylin-eosin staining and immunohistochemistry of cold snare polypectomy specimens. (a) Hematoxylin-eosin staining of cold snare polypectomy specimens (x400). (b) Tumor cells positive for thyroid transcription factor-1 immunostaining (x40). (c) Tumor cells positive for Mib-1 immunostaining (x40). (d) Tumor cells positive for synaptophysin immunostaining (x40).
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Hematoxylin and eosin-stained magnified images showed substantial proliferation of basophilic tumor-like cells extending to the mucosal fasciculus (Figure 2a). Immunohistological analysis revealed that the lesion was positive for thyroid transcription factor-1 (TTF-1; Figure 2b), Mib-1(Figure 2c), and synaptophysin (Figure 2d).
Whole body computed tomography scan. (a) A computed tomography scan shows an ill-defined mass in the left lower lobe (red arrow). (b) Enlargement of the left hilar lymph nodes (red arrow).
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SCLC (Figure 3a,b). Subsequent bronchoscopy led to a biopsy of the left lung mass, of which hematoxylin and eosin staining revealed a bare nucleated dysplastic enhancing tumor resembling a small cell carcinoma (Figure 4a).
Hematoxylin-eosin-stained and immunohistochemistry specimen for the tumor in the lower lobe of the left lung. (a) Hematoxylin-eosin staining of lung biopsy tissue (x400). (b) Tumor cells positive for thyroid transcription factor-1 immunostaining (x40). (c) Tumor cells positive for Mib-1 immunostaining (x40). (d) Tumor cells positive for synaptophysin immunostaining (x40).
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SCLC (Figure 3a,b). Subsequent bronchoscopy led to a biopsy of the left lung mass, of which hematoxylin and eosin staining revealed a bare nucleated dysplastic enhancing tumor resembling a small cell carcinoma (Figure 4a). TTF-1 (Figure 4b), Mib-1 (Figure 4c), and synaptophysin (Figure 4d).