PMC9867965_01
Brain RMN shows multiple cortico-subcortical lesions in the brain parenchyma, cerebellum, encephalic trunk with a maximum diameter of 11,6 mm with spontaneous hyperintensity and perifocal edema.
gr1.jpg
PMC9867965_01_gr1.jpg
fig0001
The patient underwent a cranial CT scan that showed multiple cortico-subcortical lesions in the brain parenchyma, cerebellum, encephalic trunk with a maximum diameter of 11,6 mm with spontaneous hyperintensity and perifocal edema; these lesions were further confirmed with a cranial MRN (Fig. 1).
a) BM biopsy shows a hypercellular BM represented mostly by myeloid elements with a slowdown maturation. b)brain parenchyma that shows hemorrhagic focal in the brain parenchyma with intravascular and intraparenchimal leukemic infiltration.
gr2.jpg
PMC9867965_01_gr2.jpg
fig0002
A postmortem examination determined as cause of death the presence of leukemic and hemorrhagic infiltration in multiple organs, especially in spleen and lymph nodes, heart, kidneys, lungs with multiple vascular microthrombi and bronchopneumonia with hemorrhagic infiltrations, liver with portal and sinusoidal thrombi associated to parenchymal necrosis, and brain with multiple hemorrhagic lesions (Fig. 2) .