PMC6307343_01
Preoperative photo showing gynecomastia.
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A 62-year-old Caucasian male presented with mastodynia, galactorrhea and right breast enlargement (Fig. 1).
Rontgen thorax showing a mass in the left upper lobe.
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Computed tomography (CT) of the chest was consistent with a solitary mass in the left upper lobe without mediastinal lymph node involvement (Fig. 2, Fig. 3).
A. Microscopic image of lung adenocarcinoma (H-E stain, x100), B. Microscopic image of the specimen depicting positivity for TTF-1 stain (x100).
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Pathology report was consistent with a poorly differentiated adenocarcinoma (T2N1M0) (Fig. 4A). Immunohistochemically, the tumor cells were highly positive for cytokeratin (CK)7, CK AE1/AE3, CK CAM5.2, carcinoembryonic antigen (CEA) and TTF-1 (Fig. 4B).
Post treatment photo showing regression of gynecomastia.
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Fifteen days later, physical examination showed regression of both gynecomastia and mastodynia and there was no nipple discharge (Fig. 5).