PMC6040299_01
Clitoromegaly.
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The Ferriman-Gallwey score for hirsutism estimation was 6 (4 in the chin, 2 in upper lip); she had acanthosis nigricans, frontal baldness, and clitoromegaly (2 cm by 3 cm) as shown in (Figure 1).
On the top, the figure shows sagittal CT section of the left ovary measures 2.74 cm by 3.14 cm. On the bottom, it shows coronal section adrenals with the largest nodule in right adrenal gland measures 3.66 cm by 1.82 cm with a left adrenal nodule.
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Abdominal computed tomography (CT) showed bilateral adrenal nodular hyperplasia as in (Figure 2).
Leydig cell tumor composed by granular cells with eosinophilic cytoplasm and round nuclei (hematoxylin and eosin stain).
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The pathology report confirmed the diagnosis of 2.8 cm Leydig cell tumor (Figure 3).
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Right ovary measures 3.8 by 2.3 cm.
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CT scan for adrenals was within normal also and right ovary measured 3.8 by 2.3cm as shown in Figure 4.
Upper left shows Leydig cell tumor of the right ovary. Upper right shows normal left ovary; microscopic examination shows cells abundant eosinophilic cytoplasm. Reinke crystals are noted.
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Pathologic report sowed 2.5 cm of Leydig cell tumor in the right ovary, while the left ovary was within normal as shown in (Figure 5).