PMC10294209_01
EGD findings showing a fungating mass (a), friable diffuse infiltrative lesions with gastric fold thickening in the gastric body (b), suggestive of malignancy.
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F1
The mass was partially circumferential and occupied about two-thirds of the luminal circumference of the stomach (shown in Fig. 1).
Biopsy of the gastric body lesion showing an infiltrating poorly differentiated adenocarcinoma. Immunohistochemical staining revealing CK7 (+), GATA3 (+), GCDFP15 focally (+), CK20 (-), and mammaglobin (-).
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F2
Biopsy of the gastric mass showed infiltrating poorly differentiated adenocarcinoma (shown in Fig. 2). Fig. 2). Further staining studies revealed estrogen receptor positive (>95%, strong intensity), progesterone receptor negative, and HER-2 negative (shown in Fig. 3).
Immunohistochemical staining positive for estrogen receptor (>95%, strong intensity), negative for progesterone receptor, and HER-2 overexpression.
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F3
Fig. 2). Further staining studies revealed estrogen receptor positive (>95%, strong intensity), progesterone receptor negative, and HER-2 negative (shown in Fig. 3).