PMC8297826_01
Comparison of clinical outcomes between LBBAP and RVP. The sketch has presented different pacing modes. Kaplan-Meier survival curves and analysis of the clinical outcomes in all patients. Figures and analysis show a statistically significant reduction in both the primary endpoint (composite endpoint of HF hospitalization or upgrade to BiVP) and upgrade to BiVP events associated with LBBAP compared with RVP. For abbreviations, see Figure 1.
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Patients were excluded if they (1) were younger than 18 years; (2) underwent pacemaker replacement or upgrading with existing leads; (3) had severe valvular diseases, congenital heart disease, or hypertrophic cardiomyopathy; (4) were diagnosed with acquired AVB after surgery for hypertrophic cardiomyopathy or other congenital heart diseases; (5) were diagnosed with persistent atrial fibrillation; and (6) were unavailable to be regularly followed up at the clinic visit for various reasons or to provide written informed consent (Figure 1).