PMC8019780_01
PMC8019780_02
Coronal (A) and axial (B) representative images from the patient's pre-treatment CT scan.
fimmu-12-660795-g001.jpg
PMC8019780_02_fimmu-12-660795-g001.jpg
f1
Computed tomography (CT) of the chest demonstrated diffuse nodular ground-glass infiltrates and widespread nodularity bilaterally (Figure 1).
PMC8019780_03
PMC8019780_04
PMC8019780_05
Change in serum LDH over time. The green data point represents initial diagnosis and initiation of treatment with trametinib. Red data points represent dates that pembrolizumab was administered. Dotted line represents upper limit of normal LDH (241 IU/L).
fimmu-12-660795-g002.jpg
PMC8019780_05_fimmu-12-660795-g002.jpg
f2
Follow up bloodwork revealed a precipitous drop in the serum lactic dehydrogenase (LDH), eventually below the upper limit of normal (Figure 2).
Timeline representation of the case.
fimmu-12-660795-g003.jpg
PMC8019780_05_fimmu-12-660795-g003.jpg
f3
A graphical representation of the case is shown in Figure 3.