PMC4408680_01
Hypercellular cytospin showing single, large, neoplastic cells with eccentric nuclei, prominent nucleoli, abundant cytoplasm, mitosis and apoptosis (a to e, x400) (a: H and E). (b) (DiffQuick) Cytospin showing abundant cytoplasm and a bubbly appearance. (c) Cell block with numerous neoplastic cells with marked apoptosis in a hemorrhagic background (H and E). (d) Positive epithelial membrane antigen (IHC). (e) Positive desmin (IHC)
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PMC4408680_01_JCytol-32-46-g001.jpg
F1
Cytospins [Figure 1a-b] and cell block [Figure 1c] were hypercellular, with numerous large, single and pleomorphic cells with an epithelioid appearance, eccentrically located and convoluted nuclei. Immunohistochemical studies performed on the cell block showed positivity of the malignant cells with vimentin, epithelial membrane antigen [EMA, Figure 1d], desmin [cytoplasmic, Figure 1e] and cytokeratin AE1/AE3.