PMC6582298_01
Doses of (a) norepinephrine, (b) dopamine and (c) vasopressin, as well as mean arterial blood pressure (MAP) from admission to the intensive care unit (ICU) to cessation of vasopressor support
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A norepinephrine CRI was started, and the dose incrementally increased (Figure 1a) due to persistent hypotension. A dopamine CRI was started and the dose was incrementally increased (Figure 1b). The cat continued to have refractory hypotension (MAP 40 mmHg) and a low-dose vasopressin CRI was initiated (Figure 1c). The norepinephrine, dopamine and vasopressin CRIs were continued (Figure 1). The dopamine dose was decreased and eventually discontinued (Figure 1b). The norepinephrine dose was decreased (Figure 1a) and the vasopressin dose was unchanged (Figure 1c). The norepinephrine and vasopressin doses were decreased, and the CRIs were eventually discontinued (Figure 1a,c). The cat's MAP stayed between 70 and 80 mmHg overnight and through the next day (Figure 1a-c).
Sloughing of the skin on the right forelimb
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The skin on the paw pads of the right thoracic and right pelvic limbs started to slough in a symmetrical fashion (Figure 2).
A line of demarcation on the right forelimb
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A line of demarcation dividing affected tissue and normal healthy skin was noted on the limbs (Figure 3).