PMC6360963_01
Ulcer measuring 2cm in diameter, with raised, red, and irregular edges, with
central granulation tissue and serous exudate
abd-94-01-0113-g01.jpg
PMC6360963_01_abd-94-01-0113-g01.jpg
f1
Clinical examination revealed a painful ulcer with pruritus measuring 2cm in diameter, with raised, hyperemic, and irregular edges, and central granulation tissue and serous exudate (Figure 1).
PMC6360963_02
Ulcer of approximately 2cm in diameter, red edges with center covered with
meliceric crusts
abd-94-01-0113-g02.jpg
PMC6360963_02_abd-94-01-0113-g02.jpg
f2
After 6 months, clinical examination revealed the presence of a painful ulcer of approximately 2cm in diameter with hyperemic edges, and center covered with a meliceric crust (Figure 2).
Gel eletrophoresis of DNA products using polymerase chain reaction (PCR):
100pb - DNA Ladder; CN - Negative control; P1 - Case 1; P2 - Case 2; CP -
Positive control with Leishmania DNA
abd-94-01-0113-g03.jpg
PMC6360963_02_abd-94-01-0113-g03.jpg
f3
In both cases, after the detection of Leishmania DNA (Figure 3) and diagnostic confirmation of ATL, the treatment chosen was N-methylglucamine antimoniate at a daily intravenous dose of 13.7 ml for 20 days.