PMC3697233_01
(a) Computed tomography (CT) scanogram/scout shows enlarged cardiac silhouette with blunting of the left costophrenic sulcus. (b) Nonenhanced chest CT image reveals a nearly isoattenuating nodular mass arising from the left posterior pericardial wall (arrow) with a large circumferential pericardial effusion (asterisks) and bilateral pleural effusions without signs of cardiac tamponade. (c) Contrast-enhanced chest CT scan shows a well-defined, enhancing nodule (arrow).
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fig1
The lesion showed enhancement on contrast-enhanced CT image (Figure 1).
Histopathologic examination of postpericardiectomy specimen reveals abundant pleomorphic malignant cells with epithelial appearance (hematoxylin and eosin, x100).
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fig2
Mitoses were frequent (Figure 2).
The tumor cells are strongly and diffusely positive for vimentin (a), calretinin (b), CK AE1/AE3 (c), and CK7 (d), with focal patchy immunoreactivity for HBME-1 (e) and CK 5/6 (f). (x200).
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fig3
Anteroposterior chest radiograph on the first postoperative day shows a decrease in cardiac silhouette with increased lung markings.
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fig4
PLAP, CEA, CD5, CD30, and CD 117. Postoperative recovery was uneventful (Figure 4), and subsequently, our patient received two cycles of chemotherapy of cisplatin and pemetrexed without any complications.