PMC9805312_01
skin lesions of the face found
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F1
Clinical findings: clinical examination revealed a right frontal exophytic nodule 2 cm long, firm, mobile, painless and not ulcerated (Figure 1). Then, it revealed an ulcerated papule on the right auricle (Figure 2), and small patches of dry, crusted skin on the face (Figure 1).
skin lesion of the right auricular pinna found
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F2
Then, it revealed an ulcerated papule on the right auricle (Figure 2), and small patches of dry, crusted skin on the face (Figure 1).
surgical removal of frontal lesion
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F3
Therapeutic intervention and follow-up: the treatment consisted of a wide surgical excision of the right frontal swelling with an "H" shaped sliding flap of the forehead (Figure 3), associated with an excision of the right auricular skin lesion.
trichilemmal proliferation (HEX10)
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F4
Anatomopathological and immunohistochemical examinations were in favour of a frontal trichilemmal carcinoma, selected in view of a trichilemmal proliferation made of endophytic cells centred by clear cells (HEX10) (Figure 4), a very marked mitotic activity (HEX40) (Figure 5), an absence of BEREP4 expression and a loss of CD 34 expression (Figure 6).
very important mitotic activity (HEX40)
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F5
Anatomopathological and immunohistochemical examinations were in favour of a frontal trichilemmal carcinoma, selected in view of a trichilemmal proliferation made of endophytic cells centred by clear cells (HEX10) (Figure 4), a very marked mitotic activity (HEX40) (Figure 5), an absence of BEREP4 expression and a loss of CD 34 expression (Figure 6).
loss of CD 34 expression
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F6
Anatomopathological and immunohistochemical examinations were in favour of a frontal trichilemmal carcinoma, selected in view of a trichilemmal proliferation made of endophytic cells centred by clear cells (HEX10) (Figure 4), a very marked mitotic activity (HEX40) (Figure 5), an absence of BEREP4 expression and a loss of CD 34 expression (Figure 6).
no local recurrence after 6 months
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F7
Post-operative follow-up was 6 months, with no recurrence or metastasis (Figure 7).