PMC9876727_01
Radiological findings on admission. Chest radiography (a) and chest computed tomography (b) showed bilateral ground-glass opacities and cystic lesion.
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Chest radiography findings showed newly developed diffuse bilateral ground-glass attenuation (Fig. 1a). High-resolution computed tomography (HRCT) revealed cystic lesions at the apices of both lungs, traction bronchiectasis, and newly developed diffuse bilateral ground-glass attenuation (Fig. 1b).
Histopathological findings of a colon biopsy. (a) Inflammatory cells infiltrating the interstitium and the accumulation of macrophages were observed (Hematoxylin and Eosin staining x40). (b) Macrophages that had phagocytosed ceroid-like granules were observed (Schmorl stain x40).
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The gross appearance of the intestinal tract on colonoscopy was unremarkable; however, a histopathological examination of a colon biopsy specimen showed inflammatory cell accumulation and macrophages that had phagocytosed ceroids, although there were no findings suggestive of vasculitis (Fig. 2a, b).
Radiological findings after two months of immunosuppressive therapy. Bilateral ground-glass opacities on chest radiography (a) and computed tomography (b) had improved compared with the imaging findings on admission.
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HRCT. However, the cystic lesions in both lungs worsened (Fig. 3a, b).