PMC9422988_01
Macroscopic view of a sagittal section of the encephalon fixed in buffered formalin highlights the neoformation in the cerebellopontine angle localization (arrow) and the uncal right herniation (asterisk).
autopsy-12-e2021396-g01.jpg
PMC9422988_01_autopsy-12-e2021396-g01.jpg
gf01
At cadaveric dissection, the brain showed smoothed convolutions and shallower grooves than normally and there was evidence of supratentorial herniation (uncal right) with tonsillar imprint (Figure 1).
Detailed macroscopic view of a longitudinal section of the yellowish color neoformation in the right pontocerebellar angle.
autopsy-12-e2021396-g02.jpg
PMC9422988_01_autopsy-12-e2021396-g02.jpg
gf02
In the right cerebellopontine subarachnoid area, there was an unencapsulated neoformation in 0.8 cm in diameter with a well-delimited surface of yellowish color and elastic consistency (Figure 2).
Photomicrograph of the cerebellopontine angle. A - adherent lipoma; a neoformation that cannot be separated from the cerebellar tissue with direct contact of the adipocytes with the nervous tissue (Masson trichrome, 50X); B - greater magnification of the neoplasm with an external portion consisting of fibrous tissue adhering to the structure (pseudocapsule) rich in small vessels and a central structure with proliferation of mature adipose tissue (H&E, 100X).
autopsy-12-e2021396-g03.jpg
PMC9422988_01_autopsy-12-e2021396-g03.jpg
gf03
On the other hand, histopathological investigations of the viscera and the cerebellopontine neoformation showed a formation composed by mature adipocytes, allowing to define it as an intracranial lipoma (Figure 3).
Photomicrograph of the Central nervous system. A - olivary body with neuronal eosinophilic degeneration (H&E,400X); B - olivary body with tissue spongiosis of the right temporal lobe (H&E, 200X); C - right temporal lobe with cortico-subcortical vascular congestion (H&E, 200X); D - right parietal lobe with leptomeningeal congestion (H&E, 400X).
autopsy-12-e2021396-g04.jpg
PMC9422988_01_autopsy-12-e2021396-g04.jpg
gf04
Areas of acute neuronal hypoxic distress in the bulbar site (olive) and diffuse cerebral edema of a severe degree, mainly in the right hemisphere, were also documented (Figure 4).