PMC5968295_01
a HE staining showing the gallbladder glands (dashed arrows) and the ectopic pancreatic tissue (black arrow); magnification x10. b HE staining showing the gallbladder muscularis layer (dashed arrow) and the ectopic pancreatic tissue (black arrow); magnification x20. c Immunohistochemical staining for cytokeratin 19 showing reactivity of the gallbladder glands (dashed arrows) and of the ectopic pancreatic tissue ducts (black arrow); magnification x20. d Immunohistochemical staining for chromogranin showing reactivity of the Langerhans islets in the ectopic pancreas; magnification x20. e Immunohistochemical staining for chymotrypsin showing reactivity of the acinic cells (arrows) in the ectopic pancreas; magnification x10. f Immunohistochemical staining for CEA showing lack of reactivity; magnification x20.
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F1
Rokitansky-Aschoff sinuses. Regarding the nodule described above, histology confirmed the presence of ectopic pancreatic tissue (Fig. 1a, b). Immunohistochemical examination of the ectopic tissue showed CK19 (Fig. 1c), CK7, and Ca19-9 positivity of the ducts. Synaptophysin, chromogranin, and somatostatin were expressed by Langerhans islets (Fig. 1d).
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