PMC5602749_01
Computed tomography revealed a tumor, with a 3-cm diameter, surrounding the hepatic hilum with the compression of the common bile duct from the outside. The tumor was enhanced in the early phase (single arrow). The extrahepatic bile duct was visible (double arrows).
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Colon biopsy revealed ulcerative colitis; computed tomography (CT) revealed a tumor surrounding the hepatic hilum and duodenum (Fig. 1).
Magnetic resonance cholangiopancreatography showed a filling defect of the common bile duct with no dilatation of the intrahepatic bile duct.
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Magnetic resonance cholangiopancreatography showed a filling defect of the common bile duct with a morphology corresponding to an external compression by the lesion (Fig. 2).
Endoscopic ultrasound showed a 30 x 20-mm submucosal tumor of the duodenal bulb.
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Endoscopic ultrasound (EUS) confirmed the diagnosis of a 30 x 20-mm submucosal tumor of the duodenal bulb (Fig. 3).
Histological examination revealed that the tumor, generated from the intramuscular layer of the common bile duct and located within the muscle layers, compressed the lumen of the bile duct.
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Histological examination revealed that the tumor, which originated from the intramuscular layer of the common bile duct and was located within the muscle layers, compressed the lumen of the bile duct (Fig. 4).
Immunohistochemical analysis showed that neoplastic cells were positive for chromogranin A, synaptophysin, and CD56. The proliferative index (Mib-1) was <2%.
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Immunohistochemical analysis showed that neoplastic cells were positive for chromogranin A, synaptophysin, and CD56 (Fig. 5).