PMC3928748_01
Whole body fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) maximum intensity projection image (a), axial fused PET/CT showed a intense uptake in the soft-tissue lesion in the left breast (b), liver lesions (c) and bone lesion (d), axial CT showing lytic bone lesion in D4 vertebra (e)
IJNM-29-32-g001.jpg
PMC3928748_01_IJNM-29-32-g001.jpg
F1
PET/CT for detection of the primary site. PET/CT showed an intense uptake in the soft- tissue necrotic lesion in the inner quadrant of the left breast [Figure 1a and b] with the same charecteristic feature of multiple hypodense liver lesions [Figure 1c]. Furthermore uptake noted in a lytic lesion in the D4 vertebra [Figure 1d and e].
Immunohistochemistry staining showing positive for chromogranin (a) and synaptophysin (b)
IJNM-29-32-g002.jpg
PMC3928748_01_IJNM-29-32-g002.jpg
F2
Patient underwent fine-needle aspiration of the breast lesion, which confirmed neuroendocrine origin [Figure 2a and b].