PMC3745295_01
Fundus findings of the left eye in case 1 before (A, C, and E) and 6 months after (B, D, and F) vitrectomy. (A and B) Fundus photographs. The preoperative fundus photograph shows the depigmented ring surrounding the area of the fluid cuff (black arrows). (C and D) FAF images. The preoperative FAF image shows the hyperautofluorescent ring corresponding to the depigmented ring. The postoperative FAF shows the same size of hyperautofluorescent ring as the preoperative one. (E and F) Optical coherence tomographic images. An anatomical closure of the MH was not achieved after the vitrectomy although the MH size became smaller.. Abbreviations: FAF, fundus autofluorescence; MH, macular hole.
opth-7-1609Fig1.jpg
PMC3745295_01_opth-7-1609Fig1.jpg
f1-opth-7-1609
The left eye had a large MH with an operculum (Figure 1A and E). The minimal and maximal diameters of the MH were 864 mum and 1,345 mum, respectively, and a depigmented ring was observed surrounding the area of the fluid cuff (Figure 1A and E). Fundus autofluorescence showed a hyperautofluorescent ring corresponding to the depigmented ring (Figure 1A and C). F). Fundus autofluorescence at this time showed the same size hyperautofluorescent ring as the preoperative one in spite of a decrease in the postoperative size of the opened MH (Figure 1D).
PMC3745295_02
Fundus findings of the right eye in case 2 before (A, C, and E) and 6 months after (B, D, and F) vitrectomy. (A and B) Fundus photographs. The preoperative fundus photograph shows the depigmented ring surrounding the area of fluid cuff (black arrows). (C and D) FAF images. The preoperative FAF image shows the hyperautofluorescent ring corresponding to the depigmented ring. The postoperative FAF shows the same size of hyperautofluorescent ring as the preoperative one. (E and F) OCT images. The preoperative OCT image shows the disruptions of the photoreceptor inner and outer segment junction line and the external limiting membrane line at the edge of the cuff of subretinal fluid (red double-headed arrow). The MH was anatomically closed but the OCT images do not show a recovery of the photoreceptor inner and outer segment junction line and the external limiting membrane line 6 months after the vitrectomy.. Abbreviations: FAF, fundus autofluorescence; MH, macular hole; OCT, optical coherence tomography.
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f2-opth-7-1609
The minimal and maximal diameter of the MH were 681 mum and 1,555 mum, respectively (Figure 2A and E). Optical coherence tomography showed disruptions of the photoreceptor inner and outer segment junction (IS/OS) line and the external limiting membrane line at the edge of the cuff of subretinal fluid (Figure 2E). A depigmented ring was seen surrounding the area of the fluid cuff, and fundus autofluorescence showed a hyperautofluorescent ring corresponding to the depigmented ring (Figure 2A and C). F). Fundus autofluorescence showed the same size of hyperautofluorescent ring as seen preoperatively despite the MH being closed (Figure 2D).
PMC3745295_03
Fundus findings of the right eye in case 3 before (A, C, and E) and 6 months after (B, D, and F) vitrectomy. (A and B) Fundus photographs. The preoperative fundus photograph shows the depigmented ring surrounding the area of fluid cuff (black arrows). (C and D) FAF images. The preoperative FAF image shows the hyperautofluorescent ring corresponding to the depigmented ring. The postoperative FAF shows the same size of hyperautofluorescent ring as the preoperative one. (E and F) OCT images. The preoperative OCT images show disruptions of the photoreceptor inner and outer segment junction line and the external limiting membrane line at the edge of the cuff of subretinal fluid (red double-headed arrow). The MH was anatomically closed, and the OCT image does not show a recovery of the photoreceptor inner and outer segment junction line and the external limiting membrane line 6 months after the vitrectomy.. Abbreviations: FAF, fundus autofluorescence; MH, macular hole; OCT, optical coherence tomography.
opth-7-1609Fig3.jpg
PMC3745295_03_opth-7-1609Fig3.jpg
f3-opth-7-1609
The minimal and maximal diameter of the MH was 818 mum and 1,494 mum, respectively (Figure 3A and E). Optical coherence tomography showed disruptions of the IS/OS line and the external limiting membrane line at the edge of the cuff of subretinal fluid (Figure 3E). A depigmented ring and corresponding hyperautofluorescent ring were observed (Figure 3A and C). F). Fundus autofluorescence showed the same size of hyperautofluorescent ring as seen preoperatively despite the MH being closed (Figure 3D).