PMC3304079_01
A 12-mm pedunculated polyp in the hepatic flexure of the colon. The polyp stalk remained intact after multiple attempts to resect with a hot snare.
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F1
The colonoscopy revealed a 12-mm pedunculated polyp in the hepatic flexure of the colon (fig. 1).
Histopathology of the polyp showing proliferation of spindle cells and inflammatory cells (arrows). Magnification x20.
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F2
Proliferation of spindle cells and infiltration of inflammatory cells such as eosinophils and plasma cells were observed (fig. 2).
Immunohistochemical stains of the polyp showing spindle cells positive for CD34 (arrows) (a), spindle cells positive for S100 (arrow) (b), and negativity for c-kit (c). Magnification x40.
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F3
Immunohistochemically, the spindle cells were positive for CD34 in their cytoplasm and S100 protein but negative for c-kit, Bcl-2 and muscle markers (fig. 3).