PMC7007033_01
Left halux, pre-treatment. Subungual hyper keratosis, edema and periungual erythema
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f1
She presented with exuberant subungual hyperkeratosis and discrete cupuliform depressions, in addition to erythema, periungual edema, and pain in the right hallux (Figure 1).
Progressive im provement of nail dystrophy five months after the first infiltration
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f2
Finally, we used intralesional infiltration with MTX 25 mg/ml (Figure 2).
Right first digit, pre-treatment (left) and after 60 days (2 infiltrations), 1 infiltration every 30 days (right)
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f3
The initial treatment consisted of topical occlusive therapy with calcipotriol and betamethasone associated with infiltrations of methotrexate at 25 mg/ml (Figure 3).