PMC6280022_01
The postoperative appearance of the excised verrucous carcinoma: A mobile 20 x 18 mm scar, located at 7-9 o-clock in the perianal area is observed.
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However, since no Human Papilloma Virus (HPV) could be found in the tissue by immunohistochemical staining, the final conclusion was verrucous carcinoma of the anogenital area (Fig. 1). The clinical presentation was a scar (a) of 20 x 18 mm located in close proximity to the anus remained from the primary excision (Fig. 1).
a) H&E stained slide (magnification x2.5) of the verrucous carcinoma (primary excision). Epidermis is seen to the upper left. Explicit dyskeratotic changes are observed. b) H&E stained slide (magnification x25) of the verrucous carcinoma (primary excision). Note the several mitosis in proximity to the basal membrane.
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A stalked, soft mobile tumor of 5 x 4 mm (b) was also observed in the perianal region at 4 o'clock (Fig. 2).