PMC6081560_01
Thickened mesangium and capillary loops PAS 200x.
CRIN2018-6746473.001.jpg
PMC6081560_01_CRIN2018-6746473.001.jpg
fig1
Upon resolution of HZ, a second biopsy was performed with findings of thickened capillary walls with lucencies, moderate mesangial matrix expansion, and no podocytes abnormality on the light microscopy (LM) (Figure 1), and negative immunofluorescent study (IF) for IgG, IgA, C3, C1q, light chains, and faint IgM on IF, and electronmicroscopy (EM) with complete (90-100%) effacement of foot processes, acellular debris in thickened capillary walls, and sparse immune deposits in mesangium (Figure 2), which were consistent with healed membranous nephropathy (MN) and minimal change disease- (MCD-) like process.
Thickened capillary walls with acellular debris, total foot process effacement on EM.
CRIN2018-6746473.002.jpg
PMC6081560_01_CRIN2018-6746473.002.jpg
fig2
Upon resolution of HZ, a second biopsy was performed with findings of thickened capillary walls with lucencies, moderate mesangial matrix expansion, and no podocytes abnormality on the light microscopy (LM) (Figure 1), and negative immunofluorescent study (IF) for IgG, IgA, C3, C1q, light chains, and faint IgM on IF, and electronmicroscopy (EM) with complete (90-100%) effacement of foot processes, acellular debris in thickened capillary walls, and sparse immune deposits in mesangium (Figure 2), which were consistent with healed membranous nephropathy (MN) and minimal change disease- (MCD-) like process.