PMC4017492_01
A. Ultrasound appearance of right papillary thyroid carcinoma. B. Surgical specimen showing papillary thyroid carcinoma: complex and branching papillae, optical clear, with overlapping and grooved nuclei (hematoxylin and eosin, original magnification x20) C. Papillary carcinoma metastatic to a lymph node (hematoxylin and eosin, original magnification x4). D.Papillary thyroid carcinoma: vascular invasion (hematoxylin and eosin, original magnification x10)
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Physical examination revealed a right thyroid nodule, confirmed by neck ultrasonography that showed a nodule 1.4 cm diameter with heterogeneous hypoechoic echogenic pattern associated with intra-parenchymal hyperechogenic microspots (Figure 1A). Total thyroidectomy was performed; histological examination confirmed the diagnosis of papillary thyroid cancer (Figure 1B), also showing metastatic involvement in 5 out 13 latero-cervical lymph nodes removed and vascular invasion (Figures 1C and D).