PMC5398114_01
Gross specimen showing large lobulated phyllodes tumor (gray arrow) and a spiculated tumor at its proximity (black arrow)
IJMPO-38-78-g001.jpg
PMC5398114_01_IJMPO-38-78-g001.jpg
F1
An another firm tumor measuring 2.5 cm with spiculated margin was seen at the periphery of large tumor, abutting it [Figure 1].
Low-power view of phyllodes tumor showing stromal predominance and epithelial cleft (H and E, x10)
IJMPO-38-78-g002.jpg
PMC5398114_01_IJMPO-38-78-g002.jpg
F2
Histology of the larger tumor showed stromal predominance occupying a low power field [Figure 2], increased cellularity, spindle cells with moderate atypia, and increased mitosis [Figure 3] of 13/10 high power field (HPF).
Phyllodes tumor showing hypercellular stroma and increased mitosis (arrows) (H and E, x40)
IJMPO-38-78-g003.jpg
PMC5398114_01_IJMPO-38-78-g003.jpg
F3
Histology of the larger tumor showed stromal predominance occupying a low power field [Figure 2], increased cellularity, spindle cells with moderate atypia, and increased mitosis [Figure 3] of 13/10 high power field (HPF).
Phyllodes tumor merging with invasive carcinoma of no special type (H and E, x10)
IJMPO-38-78-g004.jpg
PMC5398114_01_IJMPO-38-78-g004.jpg
F4
At its periphery, an epithelial tumor is seen without transition zone in between [Figure 4], consists of cells in tubules and trabeculae with stromal desmoplasiar [Figure 5].
Invasive carcinoma showing tumor cells in nests and tubules (H and E, x40)
IJMPO-38-78-g005.jpg
PMC5398114_01_IJMPO-38-78-g005.jpg
F5
At its periphery, an epithelial tumor is seen without transition zone in between [Figure 4], consists of cells in tubules and trabeculae with stromal desmoplasiar [Figure 5].