PMC4578830_01
Sagittal view of the fetus showing hypomineralization of the vertebrae (curved arrow) and an echolucent and tubular structure anterior to the spine (straight arrow), ending at the end of the sacrum.
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A detailed anatomy ultrasound performed in our center showed a male fetus with an echolucent tubular structure anterior to the spinal canal and separate from the aorta, coursing from the head to the sacrum (Figure 1).
Color Doppler showing absence of flow through the notochord.
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Color Doppler did not show any flow through the structure (Figure 2).
Postmortem radiograph showing complete absence of calcification of the vertebral bodies.
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Postmortem skeletal survey radiography showed evidence of poor mineralization of the calvarium and complete absence of ossification of the vertebral bodies (Figure 3), consistent with the diagnosis of hypochondrogenesis.