PMC5326080_01
Tissue process of the root of the tongue: coronal (A) and axial (B); contrast-enhanced CT scan showing tissue process of the left margin of the tongue measuring 20x12 mm (C, D)
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Two cervical lymphadenopathy (jugular carotid) of 5 and 1 cm in diameter (Figure 1).
Axial CT scan in parenchymal window showing wright apicalpulmonary nodule of 6 mm
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Small right laterotracheal lymphadenopathy of 8 mm of diameter (Figure 2).
Histological examination of the tumour process: A) (HE: Gx100): lymphomatous diffuse involvement of the tongue; B) (HE: Gx400): lymphoid cells of large size with significant mitotic activity; C) (CK : Gx200): absence of expression of cytokeratin in tumour population; D) (CD20 : Gx400): diffuse and intense expression of CD20 in tumour cells
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Immunohistochemical evalution was positive for CD 20, CD 79a, CD30, CD15 and anti ALK suggestive of primary non-Hodgkin's lymphoma large B cell type (Figure 3).