PMC3420495_01
Low power view of Lymph Node with plasma cell variant castleman's and showing features of Kaposi sarcoma at the top left quadrant.
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fig1
The lymph node biopsy (see Figures 1 and 2) report returned as "Atrophic follicles, germinal centre involution, lymphocytic depletion in paracortex: (i) +ve staining for kappa + lambda, (ii) appearances compatible with subacute/chronic stage of HIV lymphadenitis, and (iii) no evidence of lymphoma or carcinoma seen." 
High power view of the node with plasma cell variant of castlemans.
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fig2
The lymph node biopsy (see Figures 1 and 2) report returned as "Atrophic follicles, germinal centre involution, lymphocytic depletion in paracortex: (i) +ve staining for kappa + lambda, (ii) appearances compatible with subacute/chronic stage of HIV lymphadenitis, and (iii) no evidence of lymphoma or carcinoma seen." 
Composite picture of splenic biopsy showing H & E picture on (a), CD79a in the top and bottom (b) and HHV-8 staining cells on (c).
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fig3
A splenic biopsy (Figure 3) result showed widespread Kaposi's sarcoma and plasma cell variant multifocal Castleman's disease.
High power view of Leishmania organisms.
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fig5
A bone marrow trephine biopsy also showed Leishmaniasis (Figure 5) which was treated with ambisome. Numerous Human Herpes Virus 8 (HHV8) lymphoid cells (Figure 5) and vascular proliferation which are also strongly HHV8+:typically seen with cutaneous KS."  