PMC10386859_01
(a) Tumor cells are arranged in a sheet, diffuse infiltration and growth. HE stain. X20. (b) Most of the infiltrating lymphoid cells show positive Immunoreactivity staining for CD20. Immunohistochemical stain. X20.
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Under the pathological examination of the squamous epithelium and necrotic tissue after the biopsy, the tumor cells were ovoid, with large nuclei, obvious nucleoli, sparse cytoplasm and patchy, diffuse infiltrating growth (Figure 1).
The images before and after chemotherapy. (a and b) Baseline positron emission tomography-computed tomography showing the penile round soft tissue mass with size of about 31*30mm with intense F-18 fluorodeoxyglucose uptake. (c and d): Transaxially and sagittal magnetic resonance imaging revealing the mass of the glans penis about 23x33x26 mm after 3 cycles of chemotherapy.
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A positron emission tomography computerized tomography revealed the remarkable focal hypermetabolism (max SUV 12.6) on the head position at the penis, with a size of about 31 x 30 mm (Figure 2a and b). After 3 cycles of chemotherapy, the mass of the glans penis was revalued by MRI with a size of 23 x 33 x 26 mm (Figure 2c and d), revealing partly remission.