PMC8432166_01
Chest x-ray performed on the first day and 24 hours after suspending dornase alfa therapy in patient A.
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Before the initiation of rhDNase, the x-ray had pulmonary atelectasis with a score of three (Figure 1A). The chest x-ray 24 hours after the extubation day is presented in Figure 1B, with a score of one.
PMC8432166_02
Chest x-ray performed on the first day and 24 hours after suspending dornase alfa therapy in patient B.
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f2
At this time, her chest x-ray had a score of three (Figure 2A). The treatment was stopped at the extubation time, when the chest x-ray was normal - score of 0-1 (Figure 2B). Figure 3 shows the need for FiO2 of patients A and B during the PICU stay.
Fraction of inspired oxygen of patients A and B during the Pediatric Intensive Care Unit stay. Arrows indicate the start of dornase alfa administration.
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f3
Figure 3 shows the need for FiO2 of patients A and B during the PICU stay.