PMC6402437_01
Transanal local excision of the tumor.
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Based on this finding, the patient was scheduled for surgery, and a transanal local excision of the tumor was performed (Figure 1).
Rectal gastrointestinal stromal tumors specimen.
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Gross pathological examination of the specimen revealed a 4x2x1.8 cm mass (Figure 2), in which a tan-white 1.9 cm lesion was recognized on sectioning.
Microscopic features, H&E x10.. Notes: Tumor composed of spindle or polygonal cells with eosinophilic cytoplasm, parts of which are arranged like woven, vortex or in intersecting bundles.
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The mitotic rate was mild (<5 mitoses per 50 high-power fields), and there was no evidence of tumor cells in surgical margins (R0 excision; Figures 3 and 4).
Microscopic features, H&E x40.. Notes: Tumor composed of spindle or polygonal cells with eosinophilic cytoplasm, parts of which are arranged like woven, vortex or in intersecting bundles.
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The mitotic rate was mild (<5 mitoses per 50 high-power fields), and there was no evidence of tumor cells in surgical margins (R0 excision; Figures 3 and 4).
Immunohistochemical stain positive for C-KIT (x40).
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Immunohistochemically, neoplastic cells were diffuse and strong stained for C-KIT (CD117) and CD34 but not for smooth muscle actin (Figures 5-7).
Immunohistochemical stain positive for CD34 (x10).
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Immunohistochemically, neoplastic cells were diffuse and strong stained for C-KIT (CD117) and CD34 but not for smooth muscle actin (Figures 5-7).
Immunohistochemical stain negative for smooth muscle actin (x10).
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Immunohistochemically, neoplastic cells were diffuse and strong stained for C-KIT (CD117) and CD34 but not for smooth muscle actin (Figures 5-7).