PMC6336628_01
A. Abdominal computed tomography (CT) in July 2015 showed a 9.3 x 4.5 cm liver mass; B. Abdominal CT in April 2016 showed that the liver mass had reduced in size to 3.2 x 4.5 cm.
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F1
Computed tomography (CT) showed a 9.3 x 4.5-cm predominantly hypodense lesion within the left lobe of the liver (Fig. 1 A) and thickening of the rectum. CT on April 27, 2016 showed an ill-defined heterogeneous lesion with dystrophic calcification in segment 3 of the liver associated with capsular retraction measuring approximately 3.2 x 4.5 cm (down from 9.3 x 4.5 cm since July 2015) (Fig. 1).
A. Moderately differentiated adenocarcinoma of the sigmoid colon (hematoxylin-eosin [H&E], 4x); B. Metastatic adenocarcinoma of the liver (H&E, liver biopsy, 10x); C. Positive staining for caudal-related homeobox transcription factor 2 in the tumor cells (liver biopsy, 10x); D. Positive staining for cytokeratin 20 in the tumor cells (liver biopsy, 10x).
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F2
Immunohistochemistry indicated the tumor was positive for caudal-related homeobox transcription factor 2 and cytokeratin 20 expression (Fig. 2).