PMC8449714_01
EGD consistent with severe, diffuse hemorrhagic gastritis.
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EGD revealed severe diffuse hemorrhagic gastritis (Figure 1) with biopsies consistent with chronic gastritis and no malignant features.
Severe colitis localized at the cecum with friable mucosa.
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Colonoscopy showed localized, severe colitis at the cecum that was erythematous, friable, and ulcerative (Figure 2).
Extraluminal compression and protruding ileocecal valve resulting in narrowing of cecal lumen.
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There was also extraluminal compression of the cecum with protrusion of the ileocecal valve and luminal narrowing (Figure 3).
Circumferential cecal mass resulting in narrowing of the terminal ileum and cecal lumen.
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This ultimately revealed a cecal mass measuring 12 x 12 x 4.7 cm with the bulk of the mass protruding into the terminal ileum causing high-grade narrowing of the lumen (Figure 4). Lymphadenopathy was localized to the right lower quadrant, and no distant lymphadenopathy was observed elsewhere (Figure 4).
H&E stain showing normal colonic mucosa on the right and small lymphoma cells on left. Cyclin D1+, CD5+ (weak), K67~68%.
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A high index of Ki-67 of 65% indicates adverse prognosis (Figures 5 and 6).
Immunostaining for bcl-1 (cyclin D1).
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A high index of Ki-67 of 65% indicates adverse prognosis (Figures 5 and 6).