PMC8486032_01
Right eye; slate-gray pigmentation of conjunctiva (a); greenish-brown deposits in DM (b); hyperreflective areas on Pentacam (c); hyperreflective DM on ASOCT (d) and i-OCT (e); normal epithelium, hyperreflective dots in anterior to mid-stroma obscuring visualization of endothelium on HRT-3 (h-i); normal macular OCT and fundus (j-k); generalized decrease in sensitivity of P1-wave with loss of foveal peak on mf-ERG (l); normal blue FAF (m); mild late leak from disc and perifoveal areas on FFA (n); increased internal aberrations (o)
SJO-35-56-g001.jpg
PMC8486032_01_SJO-35-56-g001.jpg
F1
Bowman's membrane (BM), posterior stroma and Descemet's membrane (DM) [Figures 1 and 2], nuclear sclerosis grade 2 with posterior subcapsular cataract (with polychromatic luster), and intraocular pressure of 10 mmHg in both eyes. Bilateral fundus examination was limited by media haze. Corneal confocal microscopy (CCM, HRT-3, Heidelberg Engineering Inc., USA) demonstrated scattered hyperreflective dots (suggestive of bright silver precipitates) in anterior to mid-stroma that obscured visualization of the endothelium [Figures 1 and 2]. The posterior segment appeared normal on indirect ophthalmoscopy, macular OCT, and fundus autofluorescence (FAF) [Figures 1 and 2].
Left eye; slate-gray pigmentation of conjunctiva (a); greenish-brown deposits in DM (b); hyperreflective areas on Pentacam (c); hyperreflective DM on ASOCT (d); PSC as seen on i-OCT (e); normal epithelium, hyperreflective dots in anterior to mid-stroma obscuring visualization of endothelium on HRT-3 (j-i); normal macular OCT and fundus (j-k); generalized decrease in sensitivity of P1-wave with loss of foveal peak on mf-ERG (l); normal blue FAF (m); mild late leak from disc and perifoveal areas on FFA (n); increased internal aberrations (o)
SJO-35-56-g002.jpg
PMC8486032_01_SJO-35-56-g002.jpg
F2
Bowman's membrane (BM), posterior stroma and Descemet's membrane (DM) [Figures 1 and 2], nuclear sclerosis grade 2 with posterior subcapsular cataract (with polychromatic luster), and intraocular pressure of 10 mmHg in both eyes. Bilateral fundus examination was limited by media haze. Corneal confocal microscopy (CCM, HRT-3, Heidelberg Engineering Inc., USA) demonstrated scattered hyperreflective dots (suggestive of bright silver precipitates) in anterior to mid-stroma that obscured visualization of the endothelium [Figures 1 and 2]. The posterior segment appeared normal on indirect ophthalmoscopy, macular OCT, and fundus autofluorescence (FAF) [Figures 1 and 2].