PMC9969176_01
Potassium hydroxide mount showing fungal hyphae elements suggestive of mucormycosis
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FIG1
KOH examination of mandibular necrotic bone was positive for broad aseptate hyphae suggestive of mucormycosis (Figure 1).
Case 1 - mandibular mucormycosis. (A) Intra-operative picture post debridement of sequestrum until bleeding cancellous bone encountered and (B) post-operative follow-up at six months showing no evidence of residual disease and healed ridge.
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FIG2
The anti-fungal therapy was continued until the cumulative dosage of LAMB was set at 2500 mg, followed by oral posaconazole 300 mg for two weeks (Figure 2).
PMC9969176_02
Potassium hydroxide mount picture for mandible of the second case
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FIG3
KOH examination of necrotic bone showed broad aseptate hyphae, rendering a definitive diagnosis of both maxillary and mandibular mucormycosis (Figure 3).
Case 2 - mandibular mucormycosis. (A) Preoperative presentation with gross dissemination to rhinomaxillary and mandibular complex, (B) mandibular dentition showing compromised periodontal status, (C) CT-axial section of mandible showing necrotic evidence, (D) resected specimen of necrotic bone, (E) cortical bone preserved and cancellous bone debrided in the lower border of the mandible, and (F) closure of the defect after mucosal advancement.
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FIG4
The necrotic sequestrum was completely debrided, preserving the cortical plates (Figure 4).
PMC9969176_03
KOH mount picture of third case - mandible mucormycosis
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FIG5
There was no residual infection in the one-year follow-up (Figures 5-6).
Case three - mandibular mucormycosis. (A) Preoperative picture showing poor oral hygiene and pus discharge from mandibular alveolus and (B) intra-operative picture showing debrided mandibular alveolus
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FIG6
There was no residual infection in the one-year follow-up (Figures 5-6).