PMC3405564_01
Ultrasound shows multiple, ill-defined hypoechoic areas with acoustic shadowing, indicating multiple coarse calcifications within the right breast (arrows).
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fig1
An ultrasound (Figure 1) followed by an MRI of the breasts (Figures 2 and 3) were subsequently performed.  In Figure 1, the ultrasound shows multiple, ill-defined hypoechoic areas with acoustic shadowing, indicating multiple coarse calcifications within the right breast.
Transverse T2-weighted images show multiple coarse calcifications in both breasts ((a) small arrows) and a large, lobulated mass in the lower lateral quadrant of the right breast ((b) white arrow).
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fig2
An ultrasound (Figure 1) followed by an MRI of the breasts (Figures 2 and 3) were subsequently performed.  In Figure 2, transverse T2-weighted magnetic resonance images show multiple coarse calcifications in both breasts and a large, lobulated mass in the lower lateral quadrant of the right breast.
Contrast-enhanced (subtraction) MR images (a) and contrast-enhanced T1-weighted MR images (b) show a large, lobulated heterogeneously enhancing mass with irregular borders in the lower lateral quadrant of the right breast (arrows).
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fig3
An ultrasound (Figure 1) followed by an MRI of the breasts (Figures 2 and 3) were subsequently performed.  Contrast-enhanced subtraction MR images (Figure 3(a)) and T1-weighted images (Figure 3(b)) show a large, macrolobulated enhancing mass with irregular margins in the lower lateral quadrant of the right breast.
Patient's sister mammography (mediolateral oblique direction shown) showed massive calcifications in multiple, well-defined masses, some of them with adipose tissue, diagnostic of hamartomas.
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fig4
The patient's identical twin is known to have breast fibrocystic disease (Figure 4). 