PMC3358316_01
Contrast image for the comparison DBS on>DBS off.. Crosshair position indicates the location of the nucleus accumbens according to MNI standard coordinates. Activations are corrected for multiple comparisons (FWE = 0.05; cluster threshold 50 voxel). See table 1 for the corresponding list of activations.
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The electrode position was confirmed intraoperatively using stereotactic X-rays and finally by computed tomographic imaging (CT, see figure S1). The current (radius of approx. 3 mm around the active electrode contact) affected dorsal parts of the NAcc, the BSTM and the VP (see figure S1). The global contrast DBS on>DBS off (figure 1 and table 1) was computed with a stricter statistical threshold (FWE-correction, p<0.05, cluster size >50 voxels).
Behavioral data.. Upper panel: Reaction times for the "5" and "25"-selections for each condition. Lower panel: percent choices for the "25"-selection for each condition.
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In each trial of the task two numbers, 5 and 25, were presented (see figure S2).