PMC9935885_01
Contrast-enhanced abdominal computed tomography (CT) showed a large well-circumscribed mass in the lateral segment of the left hepatic lobe with early arterial phase enhancement.
CRIPA2023-2271690.001.jpg
PMC9935885_01_CRIPA2023-2271690.001.jpg
fig1
The enhancement became more pronounced in the areas surrounding necrotic changes during the portal phase (Figure 1) and eventually progressed to delayed venous phase washout.
The surgical specimen showed a well-circumscribe solid mass (14.6 x 13.0 x 10.0 cm) with central necrosis.
CRIPA2023-2271690.002.jpg
PMC9935885_01_CRIPA2023-2271690.002.jpg
fig2
The surgical specimen showed a well-circumscribed yellowish-white solid mass (14.6 x 13.0 x 10.0 cm) with central necrosis (Figure 2).
(a, b) The tumor was composed of haphazardly arranged spindle to ovoid cells with indistinct, pale cytoplasm, dense hyalinized collagenous stroma, frequent mitoses, necrosis, and characteristic staghorn-shaped blood vessels ((a) (40x) and (b) (400x)).
CRIPA2023-2271690.003.jpg
PMC9935885_01_CRIPA2023-2271690.003.jpg
fig3
Geographic necrosis, high cellularity, and frequent mitoses (more than four mitoses per 10 high power fields) are also noted (Figures 3(a) and 3(b)).
(a, b) The tumor cells showed strong and diffuse expression of CD34 ((a) 100x) and STAT6 ((b) 100x).
CRIPA2023-2271690.004.jpg
PMC9935885_01_CRIPA2023-2271690.004.jpg
fig4
The tumor cells showed strong and diffuse expression of CD34 (Figure 4(a)) and STAT6 (Figure 4(b)), confirming the diagnosis of malignant solitary fibrous tumor (SFT).