PMC4531192_01
CT of the neck indicating the largest lymph node on left measuring 36.3 mm.
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fig1
Imaging studies included a cat scan (CT) of the neck with contrast seen in Figure 1.
CT of the chest showing bilateral pulmonary nodules.
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fig2
CT of the chest with contrast, Figures 2 and 3, showed multiple bilateral pulmonary nodules and a saddle pulmonary embolism and multiple small hepatic masses and bilateral adrenal masses.
CT of the chest with arrow demarcating a saddle embolus.
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fig3
CT of the chest with contrast, Figures 2 and 3, showed multiple bilateral pulmonary nodules and a saddle pulmonary embolism and multiple small hepatic masses and bilateral adrenal masses.
Thyroid biopsy: TTF1 immunostain 100x magnification in neck mass. Brown is positive in nucleus. Thyroid transcription factor-1 is a nuclear protein important in regulating gene expression in thyroid and lung tissue.
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fig4
Core biopsy of the right thyroid nodule revealed adenocarcinoma with specimen containing papillae and psammoma bodies seen in Figures 4 and 5.
Thyroid biopsy: Napsin A immunostain 200x in neck mass. Napsin A is sensitive and specific for pulmonary adenocarcinoma. Tumor is negative.
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fig5
Core biopsy of the right thyroid nodule revealed adenocarcinoma with specimen containing papillae and psammoma bodies seen in Figures 4 and 5.
Lung biopsy: TTF1 immunostain in lung 100x magnification. Brown is positive in nucleus.
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fig6
The morphology and the immunophenotype of the lung tissue were distinct from the thyroid biopsy (Figures 6 and 7).
Lung biopsy: Napsin A immunostain 200x in lung is positive.
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fig7
The morphology and the immunophenotype of the lung tissue were distinct from the thyroid biopsy (Figures 6 and 7).