PMC9382070_01
Polyp located in distal esophagus near gastroesophageal junction prior to
starting treatment. Note typical mucosal findings of EoE surrounding the
polyp which include furrowing and edema.
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The endoscopy revealed esophageal edema, furrowing of the mucosa, and an esophageal polyp in the distal esophagus near the gastroesophageal junction (Figure 1).
Histology of the esophagus before treatment. Blue arrows indicate
eosinophils. Proximal esophagus (a) contained greater than 80 eosinophils
per high-power field. Distal esophagus (b) contained greater than 60
eosinophils per high-power field ((a) and (b) resolution 200x).
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Biopsies obtained showed significant esophagitis with greater than 60 eosinophils per high-power field (eos/hpf) in the distal esophagus and greater than 80 eos/hpf in the mid-upper esophagus (Figure 2).
Histology of the polyp before treatment. Blue arrows indicate eosinophils,
with maximum 7 eosinophils per high-power field. Ulcerations, fungus, and
viral inculsions were not seen. No glandular mucosa was present (resolution
(a) 20x, (b) 200x).
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A total of 7 eos/hpf was noted in the esophageal polyp (Figure 3).
Histology of the esophagus after treatment. Blue arrows indicate eosinophils.
Proximal esophagus (a) contained 1 eosinophils per high-power field. Distal
esophagus (b) contained 1 per high-power field ((a) and (b) resolution
200x).
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The histology showed 1 eos/hpf in both the distal and mid-upper esophagus (Figure 4), and persistent 7 eos/hpf in the esophageal polyp (Figure 5).
Histology of the polyp post treatment with proton pump inhibitor and
swallowed steroids. Blue arrows indicated eosinophils, with maximum 7
eosinophils per high-power field. Ulcerations, fungus, and viral inclusions
were not seen. No glandular mucosa was present (resolution (a) 20x, (b)
200x).
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The histology showed 1 eos/hpf in both the distal and mid-upper esophagus (Figure 4), and persistent 7 eos/hpf in the esophageal polyp (Figure 5).
Polyp located in distal esophagus near gastroesophageal junction, has
flattened and reduced in size after treatment with proton pump inhibitor and
swallowed steroids.
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However, the polyp has reduced in size since the last procedure (Figure 6).