PMC6166759_01
Lymph node biopsy (A, B) revealed follicular hypoplasia, thickening of the mantle and marginal zone with small lymphocytes surrounding the germinal center, which were hyalinized and hypoplastic, and gave rise to the "onion peel" appearance (A: H&E x40, B: H&E x10); (C) Immunohistochemical analysis: plasma cells infiltrating among interfolliclular areas with lambda light chain restriction (IHC x10); (D) plasma cells infiltrating among interfolliclular areas (H&E x40).
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PMC6166759_01_ott-11-6271Fig1.jpg
f1-ott-11-6271
Axillary lymph node biopsy (Figure 1) revealed thickening of the mantle and marginal zone with small lymphocytes surrounding the germinal center, which were hyalinized and hypoplastic with "onion peel" appearance, and surrounded by blood vessels.