PMC8159637_01
PMC8159637_02
Histopathologic images of the muscle biopsy. Hematoxylin and eosin staining ((a), 10x power) is remarkable for the presence of numerous endomysial inflammatory cells, which lead to myophagocytosis, myofiber degeneration, and atrophy. (b) A higher power image (20x) and demonstrates numerous internalized nuclei which involve the majority of myofibers, and one myofiber with an intramyofibrillar vacuole. The inflammatory cells are predominately composed of CD3 and CD8 positive T-lymphocytes and CD68 positive macrophages (not shown).
CRIID2021-9998415.001.jpg
PMC8159637_02_CRIID2021-9998415.001.jpg
fig1
HIV myopathy (Figures 1(a) and 1(b)). He later revealed similar muscular complaints in other family members on the maternal side.