PMC5301093_01
a CT of the chest demonstrating a soft-tissue mass in the left breast and in the right lung. b The resected specimen showing a tumor with pushing margins and measuring 3.6 x 2.8 x 2.6 cm. c Microscopic sections of the tumor showing malignant glands resembling adenocarcinoma of the colon. HE. x400. d Positive staining with anti-CDX-2. x200.
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F1
He underwent a CT of the chest, which confirmed the clinical impression of a large left breast mass (Fig. 1a). The cut surface revealed a grayish white, firm tumor with pushing margins, measuring 3.6 x 2.8 x 2.6 cm (Fig. 1b). The lining cells of the glands were of the tall columnar type, and the lumen often contained necrotic debris (Fig. 1c). CK7, CK20, and GATA-3 all were negative. CDX-2 was positive (Fig. 1d), confirming the diagnosis of metastasis from the colon.