PMC5192350_01
APD. Mucosal erosions of the upper and lower vermillion lips and tongue.
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fig1
Physical examination during severe flares found diffuse erosions of the vermillion lips, tongue, buccal mucosa, and palate (Fig 1).
IDP test. Wheal formation 5 minutes after IDP injection at site A with negative bacteriostatic saline and normal saline controls at sites B and C, respectively.
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fig2
APD, an intradermal progesterone test (IDP) was performed using 0.1 mL of 50 mg/mL progesterone in benzoyl alcohol with bacteriostatic and normal saline as controls. A 1.2-cm erythematous wheal immediately developed at the IDP injection site with blister formation the following day (Fig 2).
PMC5192350_02
HIV aphthae. Punched out ulcerations of the soft palate consistent with HIV aphthae without evidence of EM.
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fig3
At follow-up visits, the patient had punctate ulcerations of the soft palate, starkly different than that of prior presentations and consistent with HIV-associated aphthae (Fig 3).