PMC8339041_01
Initial presentation of the skin with ubiquitous petechial bleedings at the trunk and extremities indicating coagulopathy and/or vasculitis (endotheliitis).
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F1
Ubiquitous petechial bleedings and pale hematomas were noticed on the skin but no other signs of clinical infection (shown in Fig. 1).
Transfontanellar ultrasound of the brain on day 1 of life. Coronal (a) and parasagittal (b) indicate hyperechogenic cortical areas (hemorrhage, white arrows) and cystic periventricular lesions (black arrows).
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F2
Day 1 cerebral ultrasound demonstrated cortical hyperechogenicity and cystic periventricular lesions (shown in Fig. 2).
Sagittal T2-weighted image shows intracerebral hemorrhage with sedimentation phenomenon (arrow) (a); blood degradation products were also found in the subarachnoid spaces (arrow) on susceptibility-weighted images (b) and subdural on the left side, exemplary on T1-weighted images (c).
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F3
MRI performed on day 14 of life confirmed bilateral intracranial bleedings in and outside the brain parenchyma with frontal accentuation (shown in Fig. 3).