PMC5963136_01
Coronal contrast abdominal CT shows the hepatic metastatic lesions (white arrows) and multiple disseminated peritoneal nodules (black arrows).
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An abdominal computed tomography (CT), showed a suspicious lesion of 49 mm in segment VIII of the liver and multiple disseminated peritoneal nodules suggesting peritoneal carcinomatosis (PC) (Fig. 1).
Coronal Pet/CT image. A: nodules without metabolic activity; B: nodules with a weak hypermetabolic activity.
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A whole body 18F-FDG-PET/CT showed only a weak FDG uptake within some peritoneal nodules (Fig. 2).
Histopathological image of LGFMS characterized by fibrous and myxoid areas and swirling whorled growth patterns with low to moderate cellularity and bland cells with minimal nuclear pleomorphism.
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Initially, the diagnosis has been made exclusively on morphologic criteria including an alternance of collagenized and myxoid areas (Fig. 3).
MUC4 immunostaining showing strong and diffuse expression.
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EMA was negative but MUC4 was strongly and diffusely expressed (Fig. 4).