PMC10213406_01
Progression of treatment for acne vulgaris (swollen abscess and nodule) using adalimumab and photodynamic therapy. At the time of admission at the hospital, the image shows a swollen and inflamed abscess with a nodule (a, b). On 1st follow-up of adalimumab + photodynamic therapy, the abscess subsided significantly, and the nodule became softer and narrower than before (c, d). After the 2nd treatment of adalimumab and photodynamic therapy, the abscess and nodules have significantly subsided, leaving scattered papules and dark red scars (e, f). After four months of maintenance therapy (isotretinoin), the lesions did not recur even after discontinuation of the drug (g, h).
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F1
The patient had repeated papules and nodules on the face (Figures 1a, b). After one session of adalimumab + photodynamic therapy, the abscess subsided significantly, and the nodules became softer and smaller than before (Figures 1c, d). The follow-up visit showed that the nodules and papules had disappeared, leaving dark red scars, and there was no new rash (Figures 1e, f). After the short-term combined treatment, the patient continued to take traditional treatment (orally isotretinoin) for 4 months, and the skin lesions did not recur after stopping the drug (Figures 1g, h).