PMC8253621_01
Fasciotomy wounds on both sides of both lower legs.
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fig1
TSH levels at day 23 that were highly increased to 16.8 mU/L (reference range 0.27-4.20 mU/L), levels of T4 4.0 mg/L (reference range 5.1 -14.1) and T3 64 ng/dL (reference range 80-200 ng/dL) was diminished, whereas reverse T3 was slightly increased, and reverse T3 was slightly increased (42 ng/dL). There was a high suspicion of hypothyroidism secondary to absorption of povidone iodine after 3 weeks of extensive wound care (see wound pictures taken on day 22 in Figure 1) with PVP-I.
Spontaneous recovery of measured creatinine clearance, normalization of serum creatinine, and urinary output in the days following interruption of PVP-I exposure on ICU day 21. CVVH: continuous venovenous hemofiltration; IHD: intermittent hemodialysis; PVP-I: povidone-iodine disinfection.
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fig2
Once the exposure was interrupted, urinary iodine values gradually decreased and urinary output and measured creatine clearance increased as soon as 4 days later, in the absence of diuretics and with increasing urinary creatinine excretion (Tables 2 and 3 and Figure 2).