PMC6005294_01
Immature spherule at the late segmentation phase prior to development of endospores of Coccidioides immitis (arrow) isolated from the left flank mass. The round structures are approximately 30-40 um in diameter with 2 um thick pale basophilic cell walls and heterogeneous amorphous pale amphophilic central material. Periodic acid Schiff (PAS) stain.
CRIVEM2018-1785748.001.jpg
PMC6005294_01_CRIVEM2018-1785748.001.jpg
fig1
The fungal conidia were round structures approximately 30-40 micrometers in diameter with 2 micrometers of thick pale basophilic cell walls and heterogeneous amorphous pale amphophilic central material, consistent with immature Coccidioides immitis spherules (Figure 1).