PMC5634577_01
Skin changes at various stages: (a) on the 6th day of hospitalization showing discoloration after the muscle biopsy; (b) on the 8th day of hospitalization showing hemorrhagic necrosis; (c) on the 12th day of hospitalization after fasciotomy and debridement; (d) on the 12th day showing Integra application.
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PMC5634577_01_CRIDM2017-8915608.001.jpg
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After the muscle biopsy, he developed rapidly progressive bluish discolorations and indurations in the upper thighs which extended to the buttocks and scrotum over a period of 2 days (Figure 1(a)). The skin lesions progressed to hemorrhagic necrosis on the 8th day of hospitalization (Figure 1(b)). His course was complicated by compartment syndrome that required bilateral lower extremity fasciotomy followed by extensive debridement with artificial dermis (Integra ) application (Figures 1(c) and 1(d)).