PMC7670026_01
High resolution computerised tomography scan of a 60 year old female patient with COVID-19 (37 Military Hospital, Accra, Ghana, April 2020). Case 2: Axial image showing traction bronchiectasis in an area of ground-glass opacities (red arrows) and bilateral 'crazy paving' opacities (blue arrows).
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A computerised tomogram scan was done, the pulmonary vessels were reported as normal (Figure 2).
Haematoxylin and eosin staining of lung tissue samples from a 60 year old female patient with COVID-19 (37 Military Hospital, Accra, Ghana, April 2020). Case 2: (a) Alveolar sacs filled with alveolar macrophages (green arrow) and multinucleated giant cells (blue arrow) x400. (b) Fibrous tissue proliferation in alveolar sacs (black arrow). Also noted are alveolar macrophages (blue arrow) x400. (b) Fibroblast proliferation (green arrow) x400. (d) Diffuse alveolar damage with prominent hyaline membrane formation (black arrow) x400. (e) Thrombus at the glomerulus (blue arrow) x400. (f) Thrombus in a small pulmonary artery (blue arrow) x100.
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Microthrombi were also noted in some of the glomeruli (Figure 3).
PMC7670026_02
Radiological images of a 55 year old male patient with COVID-19 (37 Military Hospital, Accra, Ghana, May 2020). Case 3: (a) Postero-anterior chest x-ray showing bilateral ground-glass opacification and right upper and middle zone peripheral patchy opacities. (b) High resolution computerised tomography scan, coronal view, showing bilateral, ground-glass opacities with thickened interlobular and intralobular lines with 'crazy paving' appearance. Bilateral peripheral and subpleural opacities (red arrows).
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A plain chest X-ray and a computerised tomography scan were requested (Figure 4).
Haematoxylin and eosin staining of lung tissue samples from a 55 year old male patient with COVID-19 (37 Military Hospital, Accra, Ghana, May 2020). Case 3: (a) Severe pulmonary oedema, diffuse alveolar damage with hyaline membrane formation (blue arrow) x100. (b) Severe pulmonary oedema, diffuse alveolar damage with hyaline membrane formation (blue arrow) x100. (c) Large pneumocytes (blue arrow) x400. (d) Microthrombi in small pulmonary arteries (black arrows) x100. (e) Higher magnification (x400) of image (d) showing microthrombi (blue arrow) x100. (f) Interstitial widening, pulmonary oedema and prominent hyaline membranes (blue arrow).
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Microthrombi were also noted in some smaller pulmonary capillaries (Figure 5).