PMC9329676_01
Chest CT images of the patient. (A) Chest CT on December 27, 2021. (B) Chest CT imaging on December 29, 2021.
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The chest computed tomography (CT) demonstrated multiple nodular foci with partial cavitations in the lower lobes of both lungs (Figure 1A). The chest CT demonstrated small nodules and pulmonary bullae in the right lower lung (Figure 1B). CT on January 17, 2022 revealed a low-density lesion in the left frontal lobe of the brain and multiple infectious lesions accompanied by local cavities in both lungs (Figure 3B). Compared with the chest CT images on January 10, 2022 (Figure 1A), those on January 17, 2022 indicated a great alleviation of pulmonary infection in this patient (Figure 3B).
Brain MRI images of the patient. (A) Brain MRI on December 30, 2021.
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The largest lesion was approximately 4.7x3.5 cm with a low signal on T1WI, a high signal on T2WI, and an inhomogeneous high signal on FLAIR (Figure 2A).  
Chest CT images of the patient. (A) Chest CT on January 10, 2022. (B) Chest CT on January 17, 2022. (C) Chest CT on February 6, 2022. (D) Chest CT on April 16, 2022.
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The chest CT on January 10, 2022 revealed multiple nodules with partial cavities and lung vasculitis in both lungs (Figure 3A). CT on January 17, 2022 revealed a low-density lesion in the left frontal lobe of the brain and multiple infectious lesions accompanied by local cavities in both lungs (Figure 3B). Compared with the chest CT images on January 10, 2022 (Figure 1A), those on January 17, 2022 indicated a great alleviation of pulmonary infection in this patient (Figure 3B). She had no fever within one week (February 1-7, 2022), and her chest CT imaging signs were greatly recovered on February 6, 2022 (Figure 3C). TMP-SMX, ganciclovir, methylprednisolone, and voriconazole and had no obvious clinical symptoms including fever, cough, and seizure within the 2-month follow-up. The chest CT on April 16, 2022 showed several bronchial cavities in the lungs (Figure 3D).
Brain MRI images of the patient. (A) Brain MRI on January 25, 2022. (B) Brain MRI on April 16, 2022.
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Her head MRI was gradually improving (Figure 4A and B).