PMC4378320_01
Clinical photograph of the painless purple pedunculated lesion associated with the dental implant.
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The clinical differential diagnosis was pyogenic granuloma and peripheral giant cell granuloma (PGCG) (Figure 1).
Panoramic radiograph showing the presence of a dental implant in the lower left molar region. Insert: increased magnification focusing on the implant in the region of the lower left molar, showing lack of radiographic features that would be compatible with bone involvement.
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Radiographically, in the lower left molar region, the presence of an implant was observed without evidence of radiographic features that would be compatible with bone involvement (Figure 2).
Photomicrograph revealing fragments of dense connective tissue, showing proliferation of ovoid and spindle-shaped cells, multinucleated giant cells, and congested blood vessels (haematoxylin and eosin stain, original magnification x200).
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The lamina propria was composed of connective tissue containing various multinucleated giant cells surrounded by ovoid and spindle-shaped mesenchymal cells with multiple interspersed small blood vessels (Figure 3).
Immunohistochemical staining with CD68 showing strong positivity for multinucleated giant cells (original magnification x200).
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