PMC6477479_01
Esophagogastroduodenoscopy showing infiltrative mass at GE Junction and cardia on retroflexion.
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F1
Ultrathin upper endoscope was used to pass the stenosed esophageal area and further examination showed a large, infiltrative, ulcerated, circumferential mass at the gastro esophageal junction and cardia (see Fig. 1 and 2).
Esophagogastroduodenoscopy showing distal esophageal mass with luminal narrowing causing stenosis.
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F2
Ultrathin upper endoscope was used to pass the stenosed esophageal area and further examination showed a large, infiltrative, ulcerated, circumferential mass at the gastro esophageal junction and cardia (see Fig. 1 and 2).
Hematoxylin and eosin stain - showing Large atypical lymphocytes (Magnification 400x).
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F3
Subsequent biopsy revealed diffuse large B cell lymphoma (DLBCL) of the gastro esophageal junction and cardia (Fig. 3 and 4).
Large atypical lymphocytes with tumor necrosis (Hematoxylin and eosin stain - Magnification 100x).
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F4
Subsequent biopsy revealed diffuse large B cell lymphoma (DLBCL) of the gastro esophageal junction and cardia (Fig. 3 and 4).
Gastric B cell Lymphoma. CD20+ - Immunohistochemical stain - B cell marker.
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F5
On immunohistochemical stain, the tumor cells were positive for leukocyte common antigen (LCA), CD20 (CD; cluster of differentiation), CD79 and were negative for cytokeratin AE1/AE3, CD3, CD5, CD10, CD43, CYCLIN-D1, B- cell lymphoma 2 antibodies and B cell lymphoma 6 antibodies (see Fig. 5 and 6).
Gastric B cell Lymphoma. CD20+ - Immunohistochemical stain - B cell marker (Magnification 400x).
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F6
On immunohistochemical stain, the tumor cells were positive for leukocyte common antigen (LCA), CD20 (CD; cluster of differentiation), CD79 and were negative for cytokeratin AE1/AE3, CD3, CD5, CD10, CD43, CYCLIN-D1, B- cell lymphoma 2 antibodies and B cell lymphoma 6 antibodies (see Fig. 5 and 6).