PMC6664231_01
Endoscopic ultrasonography showing 11 mm lesion in the head-neck transection of the pancreas (arrow) (A); surgical specimen: an irregular, brownish nodular tissue measuring 2.5 x 1.2 x 1.1 cm and weighing 2.0 g (B).
gr1.jpg
PMC6664231_01_gr1.jpg
fig0005
An endoscopic USG was then performed, which was able to identify a single, well-defined, superficial and hypoechoic lesion measuring 11 mm, located at the head-neck transition of the pancreas (Fig. 1A). The surgical specimen was an irregular, brownish nodular tissue measuring 2.5 x 1.2 x 1.1 cm and weighing 2.0 g (Fig. 1B).
Neuroendocrine tumor of the pancreas stained with (A) Hematoxylin and Eosin; positive immunohistochemical staining for (B) synaptophysin and (C) chromogranin.
gr2.jpg
PMC6664231_01_gr2.jpg
fig0010
The specimen's immunohistochemistry was compatible with histological grade 2 neuroendocrine tumor, stained with hematoxylin-eosin (Fig. 2A) and showing a positive result for synaptophysin (Fig. 2B) and chromogranin (Fig. 2C) receptors, thus confirming insulinoma.