PMC6332758_01
A, The endometrial microbiomes of the NLDM patients before treatment. Those patients became LDM after therapeutic interventions. B, The endometrial microbiomes of the LDM patients who presented NLDM before treatment. *Patients achieved pregnancy in the following FBT. The letters below the graph show each participant. The same letter belongs to the same patient
RMB2-18-72-g002.jpg
PMC6332758_03_RMB2-18-72-g002.jpg
rmb212250-fig-0002
Sixty-four days after the initiation of Lf and 16 days from the usage of probiotic tampons (104 days from her first endometrial microbial analysis), a third endometrial microbial analysis was performed, finally resulting in LDM (Figure 2B, D-2).
PMC6332758_02
A, The endometrial microbiomes of the NLDM patients before treatment. Those patients became LDM after therapeutic interventions. B, The endometrial microbiomes of the LDM patients who presented NLDM before treatment. *Patients achieved pregnancy in the following FBT. The letters below the graph show each participant. The same letter belongs to the same patient
RMB2-18-72-g002.jpg
PMC6332758_03_RMB2-18-72-g002.jpg
rmb212250-fig-0002
Sixty-four days after the initiation of Lf and 16 days from the usage of probiotic tampons (104 days from her first endometrial microbial analysis), a third endometrial microbial analysis was performed, finally resulting in LDM (Figure 2B, D-2).
Course of treatment in Case 2 (identical to Case A in Figure 2). FBT, frozen-thawed blastocyst transfer; LVFX, levofloxacin
RMB2-18-72-g006.jpg
PMC6332758_02_RMB2-18-72-g006.jpg
rmb212250-fig-0006
She had a successful ongoing pregnancy in her next FBT (Figure 6).
PMC6332758_03
A, The endometrial microbiomes of the NLDM patients before treatment. Those patients became LDM after therapeutic interventions. B, The endometrial microbiomes of the LDM patients who presented NLDM before treatment. *Patients achieved pregnancy in the following FBT. The letters below the graph show each participant. The same letter belongs to the same patient
RMB2-18-72-g002.jpg
PMC6332758_03_RMB2-18-72-g002.jpg
rmb212250-fig-0002
Sixty-four days after the initiation of Lf and 16 days from the usage of probiotic tampons (104 days from her first endometrial microbial analysis), a third endometrial microbial analysis was performed, finally resulting in LDM (Figure 2B, D-2).
Course of treatment in Case 3 (identical to Case D in Figure 2). CFDN, cefdinir; DOXY, doxycycline; FBT, frozen-thawed blastocyst transfer; LVFX, levofloxacin; OPU, oocyte pickup
RMB2-18-72-g007.jpg
PMC6332758_03_RMB2-18-72-g007.jpg
rmb212250-fig-0007
She had a successful ongoing pregnancy in her next FBT (Figure 7).