PMC3874932_01
(A and B) Multiple, asymptomatic, variable-sized, lightly erythematous nodules on both inferior periorbital areas and the perioral area. (C and D) Non-caseating granulomatous inflammation around numerous round to oval lipid materials and multiple microcysts in the superficial and deep dermis (C: H&E, original magnification x40, D: H&E, original magnification x400). (E) A possible mechanism of granuloma formation after autologous cryopreserved autologous fat injection.
ymj-55-280-g001.jpg
PMC3874932_01_ymj-55-280-g001.jpg
F1
A 57-year-old woman presented with multiple, asymptomatic, variable-sized, erythematous nodules that had been present for the previous two months on both inferior periorbital areas and the perioral area (Fig. 1A and B). A skin biopsy was performed on the periorbital area and histopathologic findings revealed a noncaseating granulomatous inflammation around numerous round to oval lipid materials and multiple microcysts in the superficial and deep dermis (Fig. 1C and D).