PMC9193968_01
Twelve-lead electrocardiogram (ECG).
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F1
Bazetts's formula, QTc = QT/RR0.5): 481 ms, HR: 76 bpm, Figure 1A] examined 19 months before. Because of some personal reasons, her ECG examination was postponed to 5 days after the initiation of osimertinib, which showed atrial fibrillation with third degree atrioventricular block (QTc: 464 ms, HR: 40 bpm, Figure 1B). Then a pacemaker (VVI, Medtronic, E10A1) was implanted in 10 November 2021, and her ECG was normal (QTc: 488 ms, HR: 60 bpm, Figure 1C). The ECG indicated TdP (QTc: 532 ms, HR: 60 bpm, Figure 1D). Tdp (QTc: 515 ms, HR: 110 bpm, Figure 1E) with loss of consciousness occurring repeatedly. Her ECG did not return to normal (QTc:528 ms, HR:69 bpm, Figure 1F) at discharge, partly because of amiodarone use.