PMC8761671_01
The radiological images, intraoperative pictures, and pathological staining of Case 1. (A-D) Preoperative MRI indicates an intraconal lesion with both medial and lateral extension to the optic nerve. (E) Postoperative MRI shows total resection of the tumor. (F) Six-month follow-up MRI shows no recurrence. (G) Intraoperatively, the intraconal tumor is found to be tenacious. (H) The tumor is totally resected. (I) Hematoxylin-eosin (H&E) staining shows the optic nerve completely replaced by neoplastic spindle cells with a nested pattern in microscope (original magnification x200). (J) Tumor cells are positive for glial fibrillary acidic protein (GFAP) in immunochemistry (original magnification x200). (K) Ki-67 index is relatively low (original magnification x100).
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The patient recovered well postoperatively and received continuous lumber drainage for 1 week ( Figure 2 ).
PMC8761671_02
Images of Case 2. (A-C) Preoperative MRI shows an intraconal lesion in the left orbit, with both medial and lateral extension. (D-F) Six-month follow-up MRI shows no recurrence of the tumor. (G) Exposure of the intraconal tumor. (H) The carrier nerve of the tumor. (I) Inspection after total resection of the tumor.
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Postoperatively, the patient had left transient oculomotor nerve palsy, which was resolved at the 6-month follow-up ( Figure 3 ).