PMC8718702_01
Timeline illustrating clinical course and diagnostic procedures. cMRI, cranial magnetic resonance imaging; EEG, electroencephalography; CSF, cerebrospinal fluid; swab, test result of oropharyngeal swab tested for SARS-CoV-2 RNA; +, positive; -, negative; antibodies, SARS-CoV-2 anti-spike IgG (Euroimmune, Germany).
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F1
At the same time, the patient's father and his uncle developed cough, dyspnea, sore throat and muscle aches; the uncle tested positive for SARS-CoV-2 on PCR from oropharyngeal swab (Figure 1).
(A) Transverse plane of cranial MRI in constructive interference in steady state (CISS) sequence showing left-sided abducens nerve hypoplasia. Both abducens nerves are indicated by a white arrow. (B) Coronal plane of cranial MRI in native T1 sequence illustrating relative atrophy of the lateral rectus muscle (white arrow) in comparison to the contralateral right side.
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F2
Cranial contrast-enhanced magnetic resonance imaging (MRI) showed an hypoplastic left abducens nerve and atrophy of the corresponding left lateral rectus muscle compared to the contralateral side (Figure 2).