PMC5422733_01
CT scans of both cases. a In case 1, a focal patch of subpleural consolidation was observed after nivolumab re-administration. b Pneumonitis gradually improved with corticosteroids. c In case 2, diffuse ground glass opacity was observed in the lungs. d Pneumonitis had clearly improved. e Diffuse bilateral pneumonitis recurred in the lungs after nivolumab re-administration.
cro-0010-0296-g01.jpg
PMC5422733_02_cro-0010-0296-g01.jpg
F1
A CT scan revealed widespread bilateral ground-glass opacity of his lungs consistent with a diffuse alveolar damage (DAD) pattern (grade 2) (Fig. 1c). Following improvement of his respiratory status (Fig. 1d), nivolumab therapy was resumed with oral corticosteroids (0.25 mg/kg/day). A repeat CT scan revealed recurrent nivolumab-induced IP (Fig. 1e).
PMC5422733_02
CT scans of both cases. a In case 1, a focal patch of subpleural consolidation was observed after nivolumab re-administration. b Pneumonitis gradually improved with corticosteroids. c In case 2, diffuse ground glass opacity was observed in the lungs. d Pneumonitis had clearly improved. e Diffuse bilateral pneumonitis recurred in the lungs after nivolumab re-administration.
cro-0010-0296-g01.jpg
PMC5422733_02_cro-0010-0296-g01.jpg
F1
A CT scan revealed widespread bilateral ground-glass opacity of his lungs consistent with a diffuse alveolar damage (DAD) pattern (grade 2) (Fig. 1c). Following improvement of his respiratory status (Fig. 1d), nivolumab therapy was resumed with oral corticosteroids (0.25 mg/kg/day). A repeat CT scan revealed recurrent nivolumab-induced IP (Fig. 1e).