PMC4508751_01
Computed tomography (CT) scans showing a suprasellar mass including intratumoral hematoma.
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Computed tomography (CT) scans revealed a suprasellar mass including intratumoral hematoma (Fig. 1).
Preoperative magnetic resonance (MR) imaging. A, B: T1-weighted MR images demonstrate a circumscribed mass lesion in the intra- and suprasellar regions, compressing the optic chiasm. C: T2-weighted image shows a sellar lesion with mixed signal characteristics (hypointense rim and heterogeneous center). D: After gadolinium (Gd) infusion, contrast MR image revealed marginal enhancement of the tumor and minimal inhomogeneous enhancement within the mass.
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T1-weighted magnetic resonance (MR) images demonstrated a circumscribed mass lesion in the intra- and suprasellar regions, compressing the optic chiasm (Fig. 2A, B). T2-weighted image showed a hypointense rim and a heterogeneous center (Fig. 2C). After gadolinium (Gd) infusion, contrast MR image revealed marginal enhancement of the tumor and minimal inhomogeneous enhancement within the mass (Fig. 2D).
A: The histological examination of the specimen, revealing a partly necrotic, malignant tumor with focal melanotic pigmentation. Hematoxylin and eosin stain, original magnification x100. B: It was immunopositive for HMB-45 protein, which is indicative of a melanoma. Original magnification x100.
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The histological examination of the specimen revealed a partly necrotic, malignant tumor with focal melanotic pigmentation (Fig. 3A). It was immunopositive for S-100 and HMB-45 proteins (Fig. 3B), which is indicative of a melanoma.
Endoscopic investigation demonstrating primary melanoma in stomach.
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Endoscopic investigations were carried out and we diagnosed primary melanoma in the stomach (Fig. 4).