PMC4717644_01
HRCT shows extensive cystic air spaces throughout both lungs with right pneumothorax
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PMC4717644_01_13019_2016_397_Fig1_HTML.jpg
Fig1
A lung HRCT scan showed extensive cystic air spaces throughout both lungs on suspicion of lymphangioleiomyomatosis (LAM) (Fig. 1).
Histopathological findings of the lung biopsy demonstrated numerous lymphocyte infiltration and pulmonary interstitial cholesterol crystals (hematoxylin-eosin staining)
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PMC4717644_01_13019_2016_397_Fig2_HTML.jpg
Fig2
HMB-45, beta-catenin, SMA, ER, and PR, within the lung, alveolar walls and blood vessels not in keeping with LAM. However, there are diffuse pulmonary interstitial cholesterol clefts surrounded by lymphocytes, without the formation of granulomas (Fig. 2).