PMC9082194_01
T1-weighed MRI demonstrates a 26-millimeter peripherally enhancing extra-axial lesion (arrow) in the left cerebellopontine angle with adjacent edema and mild mass effect in the left cerebellum. MRI, magnetic resonance imaging.
crn-0014-0191-g01.jpg
PMC9082194_01_crn-0014-0191-g01.jpg
F1
There was adjacent edema and mild mass effect in the left cerebellum, with no evidence of hydrocephalus or midline shift (Fig. 1).
Microscopic images of the patient's tumor show focal perivascular sheets of spindle cells and areas of geographic necrosis (a; hematoxylin and eosin staining; x100). At higher magnification, a psammoma body and conspicuous nucleoli are appreciated, along with an occasional mitotic figure (b; hematoxylin and eosin staining; x400). Immunohistochemistry demonstrates focal positivity for PR (c; x400) and a Ki-67 proliferation index of 8-10% (d; x400).PR, progesterone receptor.
crn-0014-0191-g02.jpg
PMC9082194_01_crn-0014-0191-g02.jpg
F2
Immunohistochemistry demonstrated negativity for estrogen receptor, focal positivity for progesterone receptor, weak positivity for somatostatin receptor 2, and a Ki-67 proliferation index of 8-10% (Fig. 2).
T1-weighed MRI at three and a half years of follow-up demonstrates the absence of edema and no evidence of tumor recurrence. MRI, magnetic resonance imaging.
crn-0014-0191-g03.jpg
PMC9082194_01_crn-0014-0191-g03.jpg
F3
At three and a half years of follow-up, the patient is stable with no symptoms of neurologic decline and with no radiographic evidence of tumor recurrence (Fig. 3).