PMC9629142_01
(A) CECT (axial section) demonstrating a heterogeneously enhancing in right kidney with foci of calcification. A small hypodense lesion is noted on lower pole of left kidney. (B) Diagrammatic representation of the overall CECT findings with the masses (cross-hatch), the involvement of the lymph nodes, and bilateral cortical cysts. IVC, inferior vena cava; IMA, inferior mesenteric artery; IMV, inferior mesenteric vein, and LN, lymph node.
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F1
There were multiple cortical cysts bilaterally (Figure 1).
Tumor composed of tubules (arrow) with intervening mucoid matrix (arrowheads). H & E,10x.
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F2
An ultrasound-guided core needle biopsy was performed that demonstrated tumor cells composed of tubules with a mucoid matrix (Figure 2), which on immunohistochemistry was positive for vimentin and epithelial membrane antigen (Figure 3), suggestive of a mucinous tubular and spindle cell tumor variant of renal cell carcinoma.
On immnunohistochemistry, the tumor characteristically shows the mucoid material is highlighted in blue on Alcian blue, and the tumor cells are immunopositive for vimentin, epithelial membrane antigen, and are negative for CD10, CK-7, and CK-19.
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F3
An ultrasound-guided core needle biopsy was performed that demonstrated tumor cells composed of tubules with a mucoid matrix (Figure 2), which on immunohistochemistry was positive for vimentin and epithelial membrane antigen (Figure 3), suggestive of a mucinous tubular and spindle cell tumor variant of renal cell carcinoma.