PMC6360982_01
Purplish erythematous nodule with firm shiny surface on the left nasal
ala. A - lateral view. B - Lower view
abd-94-01-0099-g01.jpg
PMC6360982_01_abd-94-01-0099-g01.jpg
f1
The patient was a 36-year-old female, Caucasian, schoolteacher, who reported a single purplish erythematous nodule with a firm consistency and shiny surface, with telangiectasias, clear contour, non-pruritic, located on the left nasal ala, approximately 1.5 cm in diameter, which had grown progressively for 45 days (Figure 1).
A - Histological skin section of dense lymphocytic
infiltrate in the dermis (Hematoxylin & eosin, x50). B
- Histological skin section demonstrating the nuclear pattern of the
lymphocytes in the lesion: small to medium-sized nuclei, predominantly
regular karyotheca, hyperchromasia and perivascular and periadnexal
arrangement, with no foci of epidermotropism (Hematoxylin & eosin,
x400)
abd-94-01-0099-g02.jpg
PMC6360982_01_abd-94-01-0099-g02.jpg
f2
Lymphocyteswere small to intermediate in size (Figure 2).
A - Area with perivascular dermal lymphocytic infiltrate
(Immunohistochemistry, CD4, x400). Prevalence of CD4 T lymphocytes.
B - Area with perivascular dermal lymphocytic
infiltrate. CD4 T lymphocytes predominate over CD8 T lymphocytes
(Immunohistochemistry, CD8, x400)
abd-94-01-0099-g03.jpg
PMC6360982_01_abd-94-01-0099-g03.jpg
f3
T lymphocytes, with CD4+ immunopositivity (Figure 3). The cell proliferation index (Ki-67) was estimated at 10-15%, and there were rare CD30+ cells.