PMC8047295_01
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PMC8047295_03
PET-CT of the case 3 demonstrates bilateral thalamus and basal ganglion lesion and splenic lesions with high fluorodeoxyglucose (FDG) uptake (1a/b) while biopsy samples of the same patient demonstrate centroblastic lymphoid cells on hematoxylin & eosin staining (40x magnification) (1c) and tumor infiltration on CD20 staining (200x magnification) (1d).
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F1
PET scan (Fig 1a-b) performed upon persistent fever on 2-month follow-up revealed infiltrative lesions on spleen, a lesion with 3 cm diameter (SUVmax=13.5) and another lesion with 75 mm diameter (SUVmax=5.0), for which tru-cut biopsy was obtained, and bilateral lesions at thalamus and basal ganglion (SUVmax=7.8). Pathological examination of specimen indicated DLBCL (Fig 1c-d).
PMC8047295_04
PMC8047295_05