PMC5794352_01
Histology from the right mandible showing neoplastic cells arranged in sheets, small islands, and as individual tumor cells, H&E, 10x.
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F1
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
Histology from the right mandible showing neoplastic cells exhibit cellular and nuclear pleomorphism irregular nuclear chromatin, multiple, and prominent nucleoli with vascular infiltrations, H&E, 20x.
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F2
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
Histology from the right mandible showing tumor cells exhibit eosinophilic granular cytoplasm, H&E, 60x.
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F3
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
Immunochemistry from the right mandible biopsy showing the tumor cells are strongly positive for pancytokeratin, 10x.
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F4
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
Immunochemistry from the right mandible biopsy is positive for hepatocyte paraffin antigen-1 (HepPar-1), 10x.
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F5
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
Immunochemistry from the right mandible biopsy is positive for cytokeratin 20 (CK-20), 10x.
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F6
Histopathological examination of the incisional biopsy of the right mandible revealed neoplastic cells with immunochemistry shows the tumor cells are strongly positive for pancytokeratin, focally positive for hepatocyte paraffin antigen-1 (HepPar-1), cytokeratin 20 (CK20), and thyroid transcription factor 1 (TTF-1) and negative for CK7, CK5/6, and epithelial membrane antigen (EMA) (Figs. 1-6).
CT head and neck showed heterogenous enhancing destructive soft tissue lesion in the angle of the right mandible (indicated by arrow).
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F7
This lesion causes destruction of the angle and ramus of the right mandible as well as the lateral aspect of the inferior alveolar process (Fig. 7).
MRI of right shoulder showed an irregular enhancing lesion at the right coracoid process causing erosion of the coracoid process (indicated by arrow).
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F8
It extends intraarticularly into the anterior aspect of the right glenohumeral joint (Fig. 8).