PMC4840422_01
The characterization of leukemic cells. A. A flow cytometry analysis of the cellular surface markers. The blasts were found to be positive for CD19, CD10, TdT, CD34, MPO and HLA-DR, while they were negative for CD13, CD33 and CD3. B. The cytogenetic analysis of our case. The karyotype panel shows 44, XY, -7, der(9)t(7;9)(q11.2;p13), dic(12;17)(p11.2;p11.2), ?t(14;22)(q13,q13). The red arrow indicates the derivative chromosome der(9)t(7;9)(q11.23;p13). (For interpretation of the references to color in this figure legend,the reader is referred to the web version of this article.)
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These blasts were uniformly positive for CD19, CD10, TdT, CD34, MPO and HLA-DR based on the findings of flow cytometry (Fig. 1A), thus suggesting the presence of biphenotypic acute leukemia. A chromosomal analysis of the bone marrow cells revealed a complex karyotype including the derivative chromosome der(9)t(7;9)(q11.23;p13) (Fig. 1B).