PMC4400458_01
Renal arteriolar wall thickening, mild interstitial fibrosis and tubular atrophy areas.
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fig1
Renal biopsy (Figure 1) conducted the second week after admission revealed occlusive thrombosis in several small- and medium-sized arteries with secondary ischaemic glomerular changes.
Ischaemic glomeruli and artery wall thickening with thrombotic microangiopathy changes.
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fig2
A second renal biopsy (Figure 2) performed 2.5 months after admission, and 3 weeks before starting eculizumab, showed changes similar to those observed at the first biopsy: thrombotic microangiopathic lesions persisted and there was deterioration of interstitial fibrosis and tubular atrophy.