PMC4535005_01
The Liver Biopsy Finding in Case 1.. A. Proliferation and dilatation of the bile ducts and diffuse portal fibrosis are shown. H & E stain, magnification x 100. B. There are relatively well preserved hepatic cell cords surrounded by fibrosis and bizarre-shaped ectatic bile ductules. H & E stain, magnification x 250.
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Microscopic finding showed preserved normal hepatic cell cords with diffuse portal and periportal fibrosis surrounded by proliferated bile ductules and bizarre-shaped ectatic bile ducts (Fig. 1).
Abdominal computed tomography in case 1. A. Hepatomegaly with dilatation of the intrahepatic bile duct is demonstrated. The spleen is not seen due to previous splenectomy. B. Multiple cysts are noted in both kidneys.
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Abdominal computed tomography findings revealed Caroli's disease and hepatomegaly accompanied by multiple renal cysts (Fig. 2).
PMC4535005_02
Abdominal computed tomography in Case 2. A. Hepatomegalv with dilatation of the intrahepatic bile duct is noted. The spleen and gallbladder are not seen due to previous splenectomy and cholecystectomy. B. Multiple renal cysts and marked scoliosis are noted.
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Abdominal computed tomography revealed Caroli's disease, hepatomegaly with increased collateral circulation, and multiple renal cysts (Fig. 3).
PMC4535005_03
Abbominal computed tomography in Case 3. A. Hepatosplenomegaly and dilated intrahepatic bile duct with stones are demonstrated. There are also multiple hepatic cysts. B. Multiple cysts are noted in both kidneys.
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In our hospital, endoscopic retrograde cholangiopancreatography showed Caroli's disease with multiple intrahepatic duct stones, while abdominal computed tomography revealed hepatosplenomegaly and multiple cysts of the liver and kidney in addition to the finding of Caroli's disease (Fig. 4).