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(A) Bland-Altman plot, continuous line represents the mean inter-eye vault difference and the dashed line the limits of the 95% CI of the inter-eye differences. (B) Histogram of the inter-eye vault differences.
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The Bland-Altman analysis showed a mean vault DeltaE equal to 26.0+-122.5 microm and a 95% CI range of the differences equal to +-240.1 microm, informing that although the mean difference is close to zero, fellow eyes can exhibit large differences in the vault, Figure 3A and B.
Association between average horizontal compression (HC= ICL Size - ATA) and absolute inter-eye vault differences.
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The bivariate correlation analysis aiming to determine the influence of parameters' magnitude (average RE and LE) on the absolute vault DeltaE (amount of the difference) showed a weak but significant statistical difference for the amount of HC (R=0.27 p=0.004), Figure 4, and vault magnitude (R=0.31 p=0.001).
Absolute inter-eye vault differences for all cases and divided in three vault ranges (average RE and LE vault) groups, low: <250 microm, intermediate: [250, 750] microm and high >750 microm. Box edges represent the limits of the 25% and 75% quartile, lines inside the boxes represent the median and the whiskers the 2.5 and 97.5% percentiles.
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The differences between vault groups were statistically different Kruskall-Wallis chi2=14.4, p=0.001, with the high vault group showing larger vault DeltaE compared to the low (Mann-Whitney: U=36.5, p=0.001) and intermediate vault groups (U=638.5, p=0.007), Figure 5.