PMC8013922_01
Serpiginous, erythematous plaques with slight scale located on the medial aspect of the lower left leg and ankle.
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PMC8013922_01_10.1177_2050313X211003075-fig1.jpg
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Figures 1-3 present an example of representative lesions of the left medical ankle at stages from most to least severe.
Improvement of lesions presented in Figure 1 with reduced erythema and scale.
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PMC8013922_01_10.1177_2050313X211003075-fig2.jpg
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Figures 1-3 present an example of representative lesions of the left medical ankle at stages from most to least severe.
Near complete resolution of lesions presented in Figures 1 and 2 over a time period of approximately 3-4 months.
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PMC8013922_01_10.1177_2050313X211003075-fig3.jpg
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Figures 1-3 present an example of representative lesions of the left medical ankle at stages from most to least severe.
Sections shows (a) intact surface epithelium and (b and d) stringy dermal mucin with disrupted collagen fibres (e and f). (c) PAS/AB histochemical stains highlight stringy dermal mucin between collagen bundles.
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PMC8013922_01_10.1177_2050313X211003075-fig4.jpg
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Histologically, sections of the right lateral ankle punch biopsy showed stringy, Alcian blue positive superficial dermal mucin, disordered, fragmented collagen bundles (Figure 4(a)-(d)) and background scant superficial perivascular lymphohistiocytic inflammation. Small collections of eosinophils and neutrophils were appreciated on high power (40x) (Figure 4(e) and (f)). The surface epithelium was unremarkable and intact (Figure 4(a)), free of necrotic keratinocytes, interface change, and basement membrane thickening.
PMC8013922_02
PMC8013922_03