PMC5266152_01
Necrotic skin lesion at day 4.
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F1
The largest was a 5-centimeter necrotic lesion surrounded by an intense erythematous ring (Fig. 1).
Bulla skin lesions at day 6.
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F2
By day 4, severe skin lesions had spread even further and were necrotic and hemorrhagic, with blisters and ulcers underneath (Figs. 2 and 3).
Bulla broken with ulcers underneath, hemorrhagic lesions day 8.
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F3
By day 4, severe skin lesions had spread even further and were necrotic and hemorrhagic, with blisters and ulcers underneath (Figs. 2 and 3).
Timeline of interventions and outcomes.
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F4
Despite an aggressive resuscitation, progression was rapidly fatal (Fig. 4).