PMC6562339_01
Dark red, necrotic, slightly tender lesions developed symmetrically on MCP joints and knees.
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F1
A few days later, skin lesions appeared on the MCP and knees (Figure 1).
Hematoxylin and eosin (HE) staining shows blood vessels (white areas) with surrounding neutrophilic inflammatory aggregates (arrows), establishing the diagnosis of neutrophilic vasculitis. Picture magnification: 20x; scale bar: 50 mu.
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PMC6562339_01_fonc-09-00478-g0002.jpg
F2
Biopsy there showed a neutrophilic vasculitis, as can be seen in cutaneous forms of GPA (Figure 2).