PMC6453798_01
Liver functions parameters during normothermic machine perfusion: (A) Hepatic artery and portal vein flow rate; (B) pH; (C) lactate clearance; (D) bile production.
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At the beginning of the perfusion, the hepatic artery and portal vein flow rate were 0.200 ml/min and 1000 ml/min respectively and remained stable throughout the perfusion time (Fig. 1A). The pH at start was 7.27 and reached normal range within 2 h (Fig. 1B); lactate dropped from 5.7 to 1.6 mmol/L before implantation (Fig. 1C). A total amount of 23 g of bile was produced (Fig. 1D).
Recipient liver function tests within 10 post operative days: (A) ALT, alanine aminotransferase; AST, aspartate aminotransferase; (B) Bilirubin and Prothrombin time (PT-INR).
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INR trends during the post-operative days are displayed in Fig. 2. Intensive Care Unit stay was 72 h.