PMC8656308_01
Evolution of serum calcium and PTH concentrations.
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As shown in  Table 1  and  Figure 1 , serum calcium and PTH levels decreased after the surgical procedure, and cinacelet and denosumab could be stopped. Serum calcium and PTH levels were checked weekly during RT and showed a progressive decline ( Table 1  and  Figure 1 ).
FDG PET/CT at diagnosis of inoperable retrosternal relapse with bone invasion.
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Repeated imaging now showed a nodular, contrast-capturing lesion between the anonymous vein and the sternum, with erosion of the sternum and the first rib on the left ( Figure 2 ).
CT scan at 2 months after RT showing volume increase of the sternal lesion, probably due to pseudo-progression.
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Figure 3 ). Five months later, the clinical and biochemical situation was stable and CT-scan showed a volume decrease of the sternal lesion ( Figure 4 ).
CT scan 7 months after the end of RT showing volume decrease of the sternal lesion.
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Figure 3 ). Five months later, the clinical and biochemical situation was stable and CT-scan showed a volume decrease of the sternal lesion ( Figure 4 ).