PMC9447454_01
MRI, SPECT, and pathology (including HE, KI-67, P53, PTEN, RB1 immunohistochemistry) of the patient at first diagnosis. The arrows point to the primary tumor lesions.
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He underwent laparoscopic radical prostatectomy soon after his diagnosis. His post-surgical pathological reports showed T-stage 3b (Figure 1), and his specimen was sent for whole-exome sequencing (2018/5/30), which showed a CDK12 mutation.
PSA change, medication strategy, disease conditions, and CDK12 mutation status of the patient during treatment.
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His PSA results with important treatment annotations were displayed in Figure 2.