PMC5771154_01
Immunohistochemical characterization of skin lesion. a Haematoxylin/eosin staining, x4. b Haematoxylin/eosin staining, x10, the dotted black line defines the border area between CLL and MM tumors. c, d and e Immunohistochemical positivity for CD20, CD5 and CD23 antigens. f Immunohistochemical negativity for CD3. g Presence of mutant BRAF only in MM lesion. h MIB1 expression to evaluate the neoplastic proliferation
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PMC5771154_01_13039_2017_353_Fig1_HTML.jpg
Fig1
T3N2M0. The underlying dermis, and partially the hypodermis, were infiltrated by small CD20, CD5, CD23 positive, CD3 and cyclin D1 negative lymphoid cells (Fig. 1).