PMC9852392_01
SEEG recordings showing example ictal onsets. (A) Ictal onset showing herald spike that is wide-field on the left side marked by yellow arrow. This is followed by low-voltage, high-frequency activity within the left hippocampus and amygdala, which is followed again by wide-field, rhythmic activity. (B) Example of limbic origin seizure with periodic high-voltage spikes and sharps in the hippocampus and amygdala marked by the yellow arrow that become rhythmic periodic discharges.
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The patient underwent stereotactic depth electrode placement during which seven FIAS episodes were captured with rapid secondary generalization (Fig. 1).