PMC6500391_01
A) Erosions and edema in antrum of stomach. B) Erythema in antrum of stomach
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Endoscopy revealed erosions, ulcers in the esophagus and a pale mucosal surface with reticulated submucosal vessels accompanied by erosion and erythema in the antrum of the stomach (Fig. 1).
A) Esophagus 10x mucosal erosions, lymphocytic infiltration of lamina propria. B) Colon 10x, loss of crypt. C) Colon 10x, loss of crypts and apoptosis. D) Colon 20x, apoptosis
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Diffuse crypt dropout and mucosal erosion on rectal mucosal biopsy that is consistent with grade III GVHD was confirmed by pathologists (Figs. 2A and 2B). II GVHD were found on duodenal biopsy (Figs. 2C and 2D). Immunostaining for cytomegalovirus was negative.