PMC6057660_01
CT indicating both glottic (A) and tracheal (C) tumours. Intermediate tissue appears grossly normal (B).
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figure1
Intermediate tissue appeared grossly normal (Figure 1).
Surgical specimen verifies the presence of both a glottic and an endoluminal tracheal tumour. Intermediate tissue shows no macroscopic signs of malignancy.
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figure2
The patient underwent total laryngectomy and wide excision of the trachea which included the second tumour within safe limits (Figure 2).
(a): The tumour of the glottis (left) and the trachea (right) share the same morphological features. (b): Haematoxylin-eosin stain shows groups of tumour cells in lymphatic vessels (left). Immunomicronhistochemical stain for D2-40 antigen shows positivity of the vascular endothelium, confirming that these are indeed lymphatics (right). (B: x200).
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figure3
In the region between the two tumours, many lymphatics containing neoplastic emboli could be observed (Figure 3).