PMC4069149_01
The correlation in radiation dose and recall radiation dermatitis that followed sorafenib prescription.. Notes: (A) Forty-eight Gy, in six fractions, was delivered by HT liver SBRT. The red area received 100%, the light-blue area received 50%, and the navy-blue area received 40% of the prescribed dose. (B) The photograph of the dermatitis that followed sorafenib prescription shows that it correlated with off-target dose area. (C) The photograph shows the recovered dermatitis after medical management. The white arrow shows the area that received 50% of the prescribed dose; the yellow arrow shows the area that received 40% of the prescribed dose.. Abbreviations: HT, helical tomotherapy; SBRT, liver stereotactic body radiotherapy.
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HCC, with a thrombus extending into the inferior vena cava. HT liver SBRT with 48 Gy, in six fractions, was delivered within 2 weeks, without complications (Figure 1A). One week later, grade 2 RRD subsequently developed in the previous SBRT off-target area (Figure 1B). The patient was given clobetasol propionate topical use ointment three times a day, and the sorafenib prescription was withheld, with symptoms resolving 10 days later (Figure 1C).
The finding of magnetic resonance imaging. (A) Pre-SBRT, there was a local recurrence of HCC (white arrow) with thrombus extending into the IVC. (B) Post-SBRT, there was a partial response of the recurrent HCC (yellow arrow).. Abbreviations: HCC, hepatocellular carcinoma; IVC, inferior vena cava; SBRT, stereotactic body radiotherapy.
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In the subsequent magnetic resonance imaging report, a partial response of recurrent HCC after SBRT was noted (Figure 2A and B).