PMC6438139_01
Computed tomography of the chest.. Notes: An enlarged right supraclavicular lymph node was observed before nivolumab treatment (A). The enlarged lymph node shrank significantly after two doses of nivolumab treatment (B). The shrunken lymph node remained stable for 6 months after discontinuation of nivolumab treatment (C).
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Four weeks later, physical examination and CT showed that the enlarged lymph node shrank significantly (Figure 1), and CT showed that the atelectasis of the right lung was stable. Although nivolumab had not been used since the emergence of immune-related pneumonitis, his chest CT revealed that the tumor remained stable in the follow-up (Figure 1).
Brain MRI showed normal size and homogeneous enhancement of the pituitary gland.. Notes: Brain MRI before nivolumab treatment (A), during the onset of hypophysitis (B), and 3 months after the diagnosis of hypophysitis (C).
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Brain MRI showed multiple cerebral microbleeds and lacunar cerebral infarctions, while the size and density of the pituitary gland were normal (Figure 2).