PMC3350302_01
Coronal FLAIR (a) and axial T2 weighted images (b) showing extent of the lesion on MR scan taken at the time of MRS.
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fig1
The analysis of MRS findings was done using the standard software provided by the manufacturer. The MRI scan again confirmed the presence of extensive signal abnormality, which unchanged in size from the previous scan (Figure 1). The MRS (SV and CSI) through the abnormal areas was extensively assessed but showed no alteration in choline and N-acetyl aspartate (NAA) peaks compared to normal brain tissue and was entirely within normal limits (Figures 2 and 3).
MRS CSI spectra (grid-2A) showing no alteration in metabolite ratios between normal (Figure 2(b)) and abnormal signal area of the brain (Figure 2(c)).
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fig2
The analysis of MRS findings was done using the standard software provided by the manufacturer. The MRI scan again confirmed the presence of extensive signal abnormality, which unchanged in size from the previous scan (Figure 1). The MRS (SV and CSI) through the abnormal areas was extensively assessed but showed no alteration in choline and N-acetyl aspartate (NAA) peaks compared to normal brain tissue and was entirely within normal limits (Figures 2 and 3).
MRS SV spectrum from abnormal signal brain area (Figures 3(a) and 3(b)) showing NAA and Choline levels within normal limits.
CRIM.RADIOLOGY2011-371073.003.jpg
PMC3350302_01_CRIM.RADIOLOGY2011-371073.003.jpg
fig3
The analysis of MRS findings was done using the standard software provided by the manufacturer. The MRI scan again confirmed the presence of extensive signal abnormality, which unchanged in size from the previous scan (Figure 1). The MRS (SV and CSI) through the abnormal areas was extensively assessed but showed no alteration in choline and N-acetyl aspartate (NAA) peaks compared to normal brain tissue and was entirely within normal limits (Figures 2 and 3).
Axial T2 (a), coronal FLAIR (b), and axial T1 post-Gadolinium image (c) from 6-months followup MR scan, showing significant progression of the lesion and a new area of enhancement in the left parietal lobe.
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fig4
An area of enhancement in the left parietal lobe was also present, measuring 19 x 18 mm (Figure 4).