PMC7176925_01
(A) The Computed tomography demonstrated the calcification in right Sylvian fissure and posterior part of insula. (B,C) MRI scans revealed a lesion without dural attachment located in right insular lobe which was mainly hypointense on both T1-weighted and T2-weighted. (D) Lesion showed hypointense on susceptibility weighted imaging. Enhanced MRI showed no obvious enhancement after gadolinium administration in axial (E) and coronal (F) position.
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F1
Computerized tomography (CT) demonstrated a calcific lesion in the right Sylvian fissure and posterior part of the insula (Figure 1A). An MRI scan revealed a lesion in the right insular lobe without any dural attachment, which was primarily hypointense on both T1- and T2-weighted MRI (Figures 1B,C). Additionally, the lesion appeared hypointense on susceptibility-weighted imaging (Figure 1D), with no obvious enhancement despite administration of gadolinium contrast (Figures 1E, F).
(A) The tumor tissue arranged in swirl structure to form the meningeal corpuscle. (B) Psammoma bodies. (C) The meningeal corpuscles invade normal brain tissue. (D) GFAP staining show brain tissue (+) and meningeal corpuscles (-). Postoperative CT (E) and MRI (F,G) showed tumor gross total resection.
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F2
II meningioma of atypical type (Figures 2A-D). Immunohistochemical examinations revealed negative immunoreactivity for Ki-67, progesterone receptor, p53, epithelial membrane antigen, and positive immunoreactivity for vimentin, and somatostatin receptor 2. A follow-up gadolinium-enhanced MRI (postoperative 2 weeks) showed complete total excision of the tumor (Figures 2E-G).