PMC5351226_01
Palpable purpura and necrotic ulcers over lower extremities
IJPharm-49-124-g001.jpg
PMC5351226_01_IJPharm-49-124-g001.jpg
F1
Cutaneous examination revealed the presence of palpable purpura and large ulcers covered with necrotic eschars over the lower extremities [Figure 1].
Histopathological examination showing red blood cell extravasation, infiltration of neutrophils and eosinophils and fibrinoid necrosis (H and E, x40) in the dermis
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PMC5351226_01_IJPharm-49-124-g002.jpg
F2
A skin biopsy from the lesion revealed fibrinoid necrosis of walls of small vessels consistent with LCV [Figure 2].