PMC6346955_01
Bullous pemphigoid-like skin eruption on the legs
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In addition, tense, sero-haemorrhagic blisters developed on both legs (Figs. 1 and 2).
Bullous pemphigoid-like skin eruption on the legs
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In addition, tense, sero-haemorrhagic blisters developed on both legs (Figs. 1 and 2).
Histological examination using H&E staining and low power magnification revealed intraepidermal blistering
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Histological examination disclosed intraepidermal blistering with eosinophils and apoptotic keratinocytes inside, with significant spongiosis in the neighbouring epidermis (Fig. 3).
Histological examination using H&E staining and medium power magnification revealed eosinophils in tiny collections that were abundantly present among spongiotic areas in the epidermis (arrow) and throughout the upper part of the dermis (arrowhead)
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Discrete infiltrates of eosinophils were diffusely represented among spongiotic areas and throughout the upper part of the dermis in a perivascular and interstitial infiltrate pattern (Fig. 4).
Bullous pemphigoid-like skin eruption on forearm
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Two weeks after the use of furosemide had been discontinued, the cutaneous condition worsened; bullous lesions now appeared on the forearms (Fig. 5).