PMC6938194_01
Results of colonoscopy. (A) Colonoscopy showed an ulcer-like neoplasm situated 6 cm from the anal margin with a little bleeding, covering half of the lumen in September 2011 (arrows). (B) The re-examination of colonoscopy showed an ulcer type neoplasm on dentate line with erosion, which was brittle and subjected to hemorrhage, covering half of the lumen in November 2011 (arrows). (C) In February 2012, the re-examination of colonoscopy, which showed a 2 x 2 cm2 ulcer on distal rectal wall (near the dentate line) with white tongue coating (arrows). (D) In August 2012, the colonoscopy showed a scar with smooth surface on distal rectal wall (near the dentate line, arrows). (E) In March 2013, the colonoscopy showed a 2 cm x 4 cm neoplasm on the dentate line with erosion, which was brittle and subjected to hemorrhage (arrows).
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Colonoscopy showed an ulcer-like neoplasm situated 6 cm from the anal margin with a little bleeding, covering half of the lumen (Figure 1A). The re-examination of colonoscopy showed an ulcer type neoplasm on the dentate line with erosion, which was brittle and subjected to hemorrhage, covering half of the lumen (Figure 1B). In February 2012, he had a re-examination of colonoscopy, which showed a 2 x 2 cm2 ulcer on distal rectal wall (near the dentate line) with white tongue coating (Figure 1C). In August 2012, a contrast-enhanced MRI showed a high T2 signal slight incrassation on lower rectal wall, CEA,2.71 ng/mL; normal range: 0.0-5.0 ng/mL, CA199, 11.90 U/mL; normal range: 0.00-37.00 U/mL, and the colonoscopy showed a scar with smooth surface on distal rectal wall (near the dentate line) (Figure 1D). In March 2013, the laboratory investigation came out to be CEA, 8.65 ng/mL; normal range: 0.0-5.0 ng/mL, CA199, 27.21 U/mL; normal range: 0.00-37.00 U/mL, the colonoscopy showed a 2 cm x 4 cm neoplasm on dentate line with erosion, which was brittle and subjected to hemorrhage (Figure 1E).
Microscopic findings of the rectum mass. (A) Results showed tubular adenocarcinoma (H-E, original magnification, x100). (B) The immunoenzyme labeled Ki-67 test showed 55% of the tumor tissue was positive (IH, original magnification, x100).
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Microscopic findings of the rectum mass showed tubular adenocarcinoma (stage II-III, Figure 2A). The immunoenzyme labeled Ki-67 test showed 55% of the tumor tissue was positive (Figure 2B).