PMC6214869_01
A, B photographs showing three ill-defined, erythematous, tender nodules and plaques on both shins.
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The dermatologic examination revealed a generalized branchable erythematous rash on her face, trunk and extremities, and three discrete ill-defined erythematous, tender nodules on both shins (Fig. 1A and B).
Skin biopsy specimens from the right shin. A, Low magnification shows the superficial and deep perivascular infiltration of inflammatory cells as well as into fat lobules (hematoxylin-eosin stain, original magnification x2). B, Lymphohistiocytes and neutrophils infiltration into subcutaneous fat lobules (hematoxylin-eosin stain, original magnification x20).
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The dermatopathological studies showed an infiltration of lymphohistiocytes and neutrophils, and distorted cells around both superficial and deep blood vessels, involving the lobules of subcutaneous tissues without evidence of leukocytoclastic vasculitis (Fig. 2A and B).