PMC3337595_01
CT scan showing the lesion in the posterior wall of stomach (arrow).
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However, the CT scan (Figure 1) revealed that the lesion was arising from the posterior wall of the stomach.
Endoscopic image of the submucosal lesion in the posterior wall of the gastric body.
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(H-E, 40x): Lobular and solid tumor infiltrating the muscular layer of gastric wall.
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Histologically, the tumor was composed of round and spindle-shaped myofibroblastic cells, diffusely scattered inflammatory cells, and many vascular structures (Figures 3 and 4).
(H-E, 200x): Solid tumor cytologically composed of a compact proliferation of spindle cells arranged in a fascicular growth pattern.
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Histologically, the tumor was composed of round and spindle-shaped myofibroblastic cells, diffusely scattered inflammatory cells, and many vascular structures (Figures 3 and 4).
(ALK-1, 200x): Positive stain for ALK protein at immunnohistochemistry.
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The tumor cells showed positive immunoreactivity for vimentin and anaplastic lymphoma kinase (ALK), while being negative for c-kit, CD34, desmin, smooth muscle actin (SMA), and S-100 (Figure 5).