PMC5771725_01
Eosinophilic annular erythema (EAE). Multiple erythematous annular plaques with central clearing involving the neck, trunk, and extremities.
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Physical examination found annular erythematous plaques with central clearing on the trunk and extremities, including the palms of both hands (Fig 1).
A, Histopathology shows marked alterations in the epidermis (spongiosis and parakeratosis) and superficial and deep inflammatory infiltrate within the dermis. B and C, Perivascular and interstitial infiltrate composed of eosinophils and lymphocytes with mucin noted between dermal collagen bundles. (A to C, Hematoxylin-eosin stain; original magnifications: A, x4; B, x20; and C, x40.)
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