PMC4086848_01
Clinical photographs of ectopic cilia (top left) and hypochromic lesions on the right arm (top right).. Notes: Histologic analysis showing (A) dermal and subcutaneous pilosebaceous follicles (arrows); (B) pilosebaceous follicles (arrows) packed in a dense fibrous tissue core (*), with pores of the infundibula on the epidermal surface (arrowhead); (C) well developed sebaceous lobules (arrow); (D) bulbs of pilous follicles; (E) apocrine-lined epithelial ducts consistent with glands of Moll (arrow) and associated with a pilous follicle (arrowhead); and (F) striated orbicularis muscle fibers present in the depths of the specimen (*), with hair bulbs (arrow) superficial to these muscle fibers.
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A 6-year-old girl was referred for evaluation of a congenital lateral upper eyelid ectopic cilia cluster (Figure 1). On physical examination, she had hypochromic lesions on the right arm, diagnosed by the dermatology service as hypochromic nevi (Figure 1). Longitudinal sections and histologic analysis showed dermal and subcutaneous pilosebaceous follicles (Figure 1A and 1B), packed in a dense fibrous tissue core (Figure 1B) extending through the eyelid from the subcutaneous area, scarcely represented in the specimen. The epidermal surface showed pores of hair follicle infundibula (Figure 1B). Well developed sebaceous lobules (Figure 1C), bulbs of pilous follicles (Figure 1D), and apocrine-lined epithelial ducts consistent with glands of Moll (Figure 1E) and associated with pilous follicles were observed. Occasional striated orbicularis muscle fibers were present in the depths of the specimen (Figure 1F), with the lowest hair bulbs (Figure 1F) superficial to them.