PMC5585646_01
The lymph node showed effacement of normal architecture comprised predominantly of small lymphocytes and histiocytes ((a), H&E, x200). Scattered large atypical cells with irregular nuclei and nucleoli were observed ((b), H&E, x1000). CD20 highlights the large cells while CD3 stains numerous small T cells in the background ((c) and (d), x400).
CRIONM2017-6428461.001.jpg
PMC5585646_01_CRIONM2017-6428461.001.jpg
fig1
Ki 67 staining was approximately 30% with preferential staining of the larger cells [Figure 1].