PMC4835683_01
A 32-year-old man with a tongue-base mucocele. A, Laryngoscopy showed a smooth-margined, movable cyst at the midline of the tongue base; B and C, Enhanced CT scan depicted a well-defined cystic mass, mildly protruding between the genioglossus muscles on both sides without connection with the hyoid bone; D, and E, Lesion showed a slightly low signal intensity on the T1-weighted image and high signal intensity on the T2-weighted image without the fatty component on the fat suppressed image (not shown); F, Histopathologic examination revealed a large cystic space in the vicinity of minor salivary gland acini and ducts (hematoxylin and eosin stain, x 40). Extravasation of mucus from a salivary duct was noted (indicated by an arrow); G, The cystic space containing a mucus pool had no epithelial lining surrounded by fibrotic connective tissue (hematoxylin and eosin stain, x 100).
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Laryngoscopic examination revealed a soft movable cyst protruding from the midline of the tongue base without tenderness (Figure 1A). On the enhanced computed tomography (CT) scan of the neck, a thin-walled cystic mass (10 to 20 Hounsfield units [HUs]) was noted without an enhancing solid component, measuring 2.8 x 2.5 x 2.8 cm (Figure 1B and C). T2-weighted image and slightly low signal intensity on the T1-weighted image when compared with the intrinsic tongue muscles (Figure 1D and E). The MRI revealed no solid component or fat in the lesion. The cyst has no epithelial lining or malignant cells, which was consistent with the appearance of mucoceles on microscopic examination (Figure 1F and G).