PMC8267377_01
Histological and immunophenotypic results of excisional biopsy of left cervical lymph node. Hematoxylin and eosin (H&E)-stained sections is seen (A). Immunohistochemical staining of these specimens shows that the infiltrated lymphocytes are positive for CD20 (B), CD21 (C) of follicular dendritic cells, and EBER (D). (magnification x20).
fonc-11-681432-g001.jpg
PMC8267377_01_fonc-11-681432-g001.jpg
f1
Figure 1 ). Flow cytometry identified a population of kappa restricted B cells that were positive for CD19, CD20, CD79a, CD30 and negative for CD5, CD10, CD34, CD38, and Bcl-2.
Histological and immunophenotypic results of excisional biopsy of the axillary lymph node and peripheral blood smear. H&E-stained sections is seen (A), and immunohistochemical staining of the specimens shows that the diffuse infiltrated lymphocytes are positive for CD20 (B) and EBER (C) (magnification x20). Wright's staining of peripheral blood smear showed typical atypical lymphocytes (D) (magnification x400).
fonc-11-681432-g002.jpg
PMC8267377_01_fonc-11-681432-g002.jpg
f2
Re-biopsy of the axillary lymph node supported the diagnosis of EBV-positive DLBCL, and atypical lymphocytes were noted in the peripheral blood smear ( Figure 2 ).