PMC10375206_01
(a) Macroscopic photography of the eyelid showing ulcerated mass on the eyelid. (b) Anterior segment photography showing ulcerated mass before punch biopsy.
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F1
A 28-year-old male was referred to our clinic for an ulcerated, hyperemic, and nodular mass on his right upper eyelid that grew rapidly within 2 weeks (Fig. 1a). Hence, the symptoms of the patient progressed despite treatment, a punch biopsy from the lesion was performed which did not distinguish infective pathologies or malignancy (Fig. 1b).
(a-c) Hematoxylin and eosin staining of dermis showing abundant eosinophils, histiocytes, and lymphoid infiltrate. (d) Immunohistochemical analysis revealing CD30-positive lymphocytes.
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F2
Abundant eosinophils, histiocytes, and lymphoid infiltrate were detected in dermis (Figures 2a-c). CD30-positive lymphocytes in immunohistochemical analysis (Fig. 2d). CD30-positive lymphoproliferative diseases and insect bite reactions were evaluated in the differential diagnosis.
(a) Photograph of the eyelid after incisional biopsy. (b) Tarsal conjunctival photography after the incisional biopsy.
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F3
However, following incisional biopsy, the lesion rapidly regressed in 7 days (Figs. 3a-b).