PMC5385779_01
In an 18-year-old female at 15-week gestation, transabdominal ultrasonography (TAS) of pelvis (A-C) shows mildly enlarged, low lying, posteriorly placed placenta. Lower part of the placenta shows multiple anechoic cysts (arrows) which are extending inferiorly and covering the internal os. On color Doppler imaging (D), low velocity signals were seen in the multicystic placental lesion
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F1
On color Doppler, low velocity blood flow was seen within the multicystic placental lesion [Figure 1].
TAS of the fetus showing no gross structural anomaly
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F2
A single live fetus of 15-week gestational age without any gross structural anomaly was seen [Figure 2].
Histopathological examination (higher magnification) of placental lesion shows hydropic stem cell villi (long white arrow), central cistern (small white arrow) containing myxoid stroma and few congested blood vessels (small black arrows) in the stroma of hydropic villi with interspersed normal villi (long black arrow)
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F3
There was characteristic absence of trophoblastic proliferation around the periphery of the abnormal villi, absence of stromal cell inclusions, and scalloping of villous surface (diagnostic hallmark of molar pregnancy) [Figure 3].