PMC3031237_01
A) Computed tomography image revealing a well demarcated mass in the anterior portion of the left parotid gland resembling a mixed tumor (red arrow). B) Histopathological image showing peri-neural invasion by the tumor and cohesive clusters of neoplastic cells (hematoxylin and eosin stain, original magnification 250x). C) High magnification image demonstrating oncocytic cells with abundant and finely granular cytoplasm and moderately pleomorphic nuclei located centrally or peripherally (hematoxylin and eosin stain, original magnification 400x).
1752-1947-5-11-1.jpg
PMC3031237_01_1752-1947-5-11-1.jpg
F1
A computed tomography (CT) scan revealed a 20x25 mm mass in the anterior portion of the gland, near the parotid duct, resembling a mixed tumor (Figure 1A). Microscopic examination revealed that the neoplasm had replaced a wide area of the parotid gland and peri-neural invasion was found (Figure 1B). The cytoplasm was abundant, eosinophilic and finely granular, characteristics indicative of oncocytes (Figure 1C).
A) Computed tomography image four years after first surgery revealing a cervical lymph node enlargement (red arrow). B) Histopathological study of cervical specimen showing metastatic tumor infiltration by oncocytic cells (hematoxylin and eosin stain, original magnification 400x).
1752-1947-5-11-2.jpg
PMC3031237_01_1752-1947-5-11-2.jpg
F2
A CT scan demonstrated several enlarged lymph nodes in the left parotid gland and on the left side of the neck (Figure 2A). A microscopic examination of tissue samples confirmed that three lymph nodes were positive for metastases, as they had the same histopathological features as the primary tumor (Figure 2B).