PMC6586952_01
Chest roentgenogram at the first presentation showing massive tumor in the left upper lung field and multiple pulmonary nodules in both lung fields.
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A chest roentgenogram showed a massive tumor in the left upper lung field and multiple pulmonary nodules in both lung fields (Fig. 1).
Computed tomography at the first presentation showing a 10-cm massive pulmonary tumor in the left upper lobe and multiple nodules in both lung fields.
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Chest computed tomography (CT) revealed a massive 10-cm pulmonary tumor in the left upper lobe and multiple nodules in the both lung fields (Fig. 2).
Histological examination of transbronchial lung biopsy specimens obtained from the left pulmonary mass revealing proliferation of polyhedral and spindle atypical cells.
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Histological examination of transbronchial lung biopsy specimens obtained from the left pulmonary mass revealed pleomorphic carcinoma of the lung (Fig. 3).
Chest CT images obtained after 2 weeks (A), 2 months (B), 12 months (C), and 17 months (D) in a patient who received single pembrolizumab treatment.
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However, after 14 days of the administration, chest CT images revealed the appearance of a large cavity in the left upper lobe tumor and interstitial lung disease in the right upper lobe (Fig. 4A). Follow-up chest CT images revealed gradual tumor shrinkage (Fig. 4).