PMC3918512_01
STN infarction adsacent to the DBS lead.. Subthalamic nucleus infarction (red arrow) is seen adjacent to the previously placed deep brain stimulator.
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As part of the preoperative protocol, high-resolution MRI was done and revealed a new T2 high- and T1 low-intensity lesion within the right STN that was directly adjacent to the right STN-DBS lead (Figure 1).
Intraoperative physiological recordings.. The representative microrecording in globus pallidus internus (A) and histogram of inter-spike interval (B). (C) Spectral analysis of local field potential during stimulation. Spectrogram showing the occurrence of the stimulation artifact (107 Hz) from the previous ipsilateral deep brain stimulation implant in the subthalamic nucleus and oscillatory activity in the time vicinity of the stimulation. Quantification of theta (4-8 Hz) and beta (12-25 Hz) band oscillatory power revealed an increase in theta band activity.
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Figure 2 illustrates a representative microrecording (Figure 2A) and histogram of inter-spike interval (Figure 2B). This stimulation had no effect on the beta band; on the other hand, theta band activity was increased (Figure 2C).