PMC8473713_01
Baseline right eye fundus fundus photo of patient #1 showing papilledema in the superior part of optic disc and chorioretinal scar and fibrosis near the macula (A). Baseline OCT (B) shows optic disc elevation, pigment epithelium detachment with a few pockets of intraretinal liquid and subretinal fibrotic tissue in the macula area. After treatment, there was no apparent change on fundus photograph whereas OCT scans shows persistence of the disc elevation (C) and resorption of the intraretinal liquid (D).
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Fundus examination revealed papilledema covering the upper half of the optic disc, a chorioretinal scar, and fibrotic lesion near the macula in the right eye (Figure 1). Optical coherence tomography (OCT) of the right eye showed an elevated optic disc, thickening of peripapillary retinal fiber layer (RNFL) in the superior, inferior and nasal sectors, pigment epithelium detachment (PED), small pockets of intraretinal fluid, and subretinal fibrosis in the macula area (Figure 1). A month later, visual acuity in the right eye increased to 0.5, fundus photography showed no change relative to baseline, and OCT scan revealed persistence of the optic disc elevation (Figure 1) and complete resorption of the intraretinal fluid (Figure 1).
PMC8473713_02
PMC8473713_03
Baseline fundus photo (A) of the left eye of patient #3 displaying papilledema with retinal hemorrhage along the superotemporal retinal vein. OCT scan shows elevation of the optic disc, an epiretinal membrane, posterior vitreous detachment (PVD), and slight thickening of the macula (B). Post-treatment imaging depicts almost complete resorption of the papilledema (C), substantial resorption of the retinal hemorrhage (C), significant reduction in optic disc elevation (D), PVD, and a macular serous detachment (D).
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Fundus examination was normal in the right eye, whereas the left eye had papilledema with superotemporal juxtapapillary hemorrhage resembling a branch retinal vein occlusion (Figure 2). OCT scans revealed posterior vitreous detachment in both eyes with papilledema in the left eye (Figure 2) and small retrofoveal retinal detachment in the right eye. Fundus examination was normal in the right eye and showed partial resorption of both papilledema and retinal hemorrhage in the left eye (Figure 2). In the left eye, it confirmed the significant decrease of papilledema but revealed an important macular edema (Figure 2).