PMC3542777_01
Dermal Lactating adenoma (H&E x40)
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Microscopic tissue sections revealed a typical lactating adenoma showing typical mammary glands with classic secretory activity, which included numerous intracytoplasmic lipid vacuoles, arranged in lobules with large alveolar spaces separated by fine fibrovascular trabeculae (Figure 1 and Figure 2).
Secretory changes in lactating adenoma (H&E x400)
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Microscopic tissue sections revealed a typical lactating adenoma showing typical mammary glands with classic secretory activity, which included numerous intracytoplasmic lipid vacuoles, arranged in lobules with large alveolar spaces separated by fine fibrovascular trabeculae (Figure 1 and Figure 2).
Glands are focally arranged in a lobular pattern similar to that in breast tissue and show cystic changes and apocrine-type secretion. (a H&E x40) (b H&E 200)
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Some glands were dilated cystic or showing apocrine changes (Figure 3).
Vulvar glands organised on lobuli, resembling those of mammary glands
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Occasionally, glands were arranged in true lobuli, resembling those of mammary glands (Figure 4 and Figure 5).
Dermal fibroadenoma(H&E x40)
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Occasionally, glands were arranged in true lobuli, resembling those of mammary glands (Figure 4 and Figure 5).
Depressed glands and ducts in dense fibrotic stroma resemble those in fibroadenoma of the breast (H&E x200)
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The stromal cells proliferated around ducts in a circumferential fashion (Figure 6).