PMC10247993_01
Changes in tumor size before and after chemotherapy on CT scans + Portal Vein, * Coeliac Axis. Before chemotherapy CT scan of the abdomen shows a lesion in the pancreatic neck with portal vein and coeliac axis invasion (A1, B1). After 2 cycles of chemotherapy, the tumor had significantly decreased in size (A2, B2). After 5 cycles of chemotherapy (A3, B3). After 6 cycles of chemotherapy(A4, B4).
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After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ).
(A1-A9) Pancreatic tumor biopsy pathology results before chemotherapy. (B). Post-surgery tissue of the tail of the pancreas and spleen; (C1) Post-surgery pathology: Residual pancreatic ductal adenocarcinoma cells; (C2) Post-surgery pathology: Pancreatic islet cell hyperplasia and ductal dilation; (C3) Intraoperative pathology result: no obvious malignant cells on the cut end of the pancreas.
fonc-13-1155233-g002.jpg
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After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ). The surgery was successful ( Figure 2B ). The pathology report after the surgery ( Figures 2C1-3 ) showed a small amount of residual adenocarcinoma at the original tumor site with islet cell proliferation, ductal dilation, no obvious intratumoral thrombosis or nerve invasion, and no lymph node metastasis.
Trend of change in tumor marker expression level before and after chemotherapy.
fonc-13-1155233-g003.jpg
PMC10247993_02_fonc-13-1155233-g003.jpg
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After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ). The pathology report after the surgery ( Figures 2C1-3 ) showed a small amount of residual adenocarcinoma at the original tumor site with islet cell proliferation, ductal dilation, no obvious intratumoral thrombosis or nerve invasion, and no lymph node metastasis.
PMC10247993_02
Changes in tumor size before and after chemotherapy on CT scans + Portal Vein, * Coeliac Axis. Before chemotherapy CT scan of the abdomen shows a lesion in the pancreatic neck with portal vein and coeliac axis invasion (A1, B1). After 2 cycles of chemotherapy, the tumor had significantly decreased in size (A2, B2). After 5 cycles of chemotherapy (A3, B3). After 6 cycles of chemotherapy(A4, B4).
fonc-13-1155233-g001.jpg
PMC10247993_02_fonc-13-1155233-g001.jpg
f1
After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ).
(A1-A9) Pancreatic tumor biopsy pathology results before chemotherapy. (B). Post-surgery tissue of the tail of the pancreas and spleen; (C1) Post-surgery pathology: Residual pancreatic ductal adenocarcinoma cells; (C2) Post-surgery pathology: Pancreatic islet cell hyperplasia and ductal dilation; (C3) Intraoperative pathology result: no obvious malignant cells on the cut end of the pancreas.
fonc-13-1155233-g002.jpg
PMC10247993_02_fonc-13-1155233-g002.jpg
f2
After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ). The surgery was successful ( Figure 2B ). The pathology report after the surgery ( Figures 2C1-3 ) showed a small amount of residual adenocarcinoma at the original tumor site with islet cell proliferation, ductal dilation, no obvious intratumoral thrombosis or nerve invasion, and no lymph node metastasis.
Trend of change in tumor marker expression level before and after chemotherapy.
fonc-13-1155233-g003.jpg
PMC10247993_02_fonc-13-1155233-g003.jpg
f3
After 6 cycles of chemotherapy, repeat abdominal CT showed progressive tumor shrinkage ( Figures 1A1-B4 ), and tumor marker expression levels gradually decreased ( Figure 3 ). The pathology report after the surgery ( Figures 2C1-3 ) showed a small amount of residual adenocarcinoma at the original tumor site with islet cell proliferation, ductal dilation, no obvious intratumoral thrombosis or nerve invasion, and no lymph node metastasis.