PMC5613271_01
(A, B, C) Multiple syringomas located near the eyes, on the neck, and on the thorax.
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F1
Dermatological examination revealed some skin-colored lesions around the eyes, and multiple, yellow-brown pigmented papular lesions under the chin, on the neck, the trunk, on both breasts (Figure 1 A-C), and the abdomen measuring 1 to 5 mm in diameter (Figure 2 A-C).
(A, B, C) Coexistence of bilateral nipple areolae vitiligo and eruptive syringoma.
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F2
Dermatological examination revealed some skin-colored lesions around the eyes, and multiple, yellow-brown pigmented papular lesions under the chin, on the neck, the trunk, on both breasts (Figure 1 A-C), and the abdomen measuring 1 to 5 mm in diameter (Figure 2 A-C).
(A, B) Diagnosis of syringoma was established in the histopathological examination by determining dilated cystic cavities lined with epithelial and cuboidal cells (H&E x100, x200).
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F3
Histopathological examination established diagnosis of syringoma by determining dilated cystic cavities lined with epithelial and cuboidal cells (Figure 3 A, B).
(A) Edema and erythema after cryosurgery. (B) Partial remission after therapy.
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F4
Topical tretinoin and systemic isotretinoin 20 mg for 6 months also resulted in only slight flattening of lesions (Figure 4 A, B).