PMC10132894_01
Anti-S antibody titer after primary vaccination and before and after booster vaccination. Anti-S antibody titer levels are shown for the RA patient taking MTX (yellow circle), poor responder HCW (blue circle), and good responder HCW (black circle). The time course of the titers of the RA patient and poor HCW are illustrated by solid lines. The measured values of good responder HCWs are presented in Supplementary Table S1. Overlapping circles are displayed as horizontal shifts. Anti-S antibody: antispike antibody, RA: rheumatoid arthritis. HCW: healthcare worker, MTX: methotrexate.
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fig1
The anti-S antibody titers of seven HCWs indicated at 10 days were beyond the upper limit of the assay in six (good responders) of seven HCWs and 909 U/mL in one (poor responder) (Figure 1).