PMC5850893_01
Patient 1, bone marrow with T-cell ALL: (a) H&E core biopsy, 500x; (b) aspirate cytology, 1000x.
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fig1
Patient 1 is a 31-year-old gentleman diagnosed with T-cell ALL after presenting with diffuse petechial rash, cervical lymphadenopathy, abdominal pain, and a WBC of 121 K/muL with 40% blasts (Figure 1).
Patient 1, erythematous patches and plaques of PTCL distributed predominantly on torso and upper extremities.
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fig2
The patient developed high grade fever and over one hundred erythematous plaques on his trunk, upper extremities, and lower extremities (Figure 2).
Patient 1, right flank skin with PTCL: (a) H&E, 100x; (b) H&E, 400x; (c) CD3, 100x; (d) TdT immunoperoxidase, 400x; (e) TCR gamma, 200x.
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fig3
Skin biopsy showed NHNCgammadelta PTCL (Figure 3) as did staging bone marrow biopsy (Figure 4).
Patient 1, bone marrow with PTCL: (a) H&E, 40x; (b, c) aspirate cytology, 1000x; (d) CD3, 100x.
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fig4
Skin biopsy showed NHNCgammadelta PTCL (Figure 3) as did staging bone marrow biopsy (Figure 4).
PMC5850893_02
Patient 2; mediastinal mass with T-cell ALL: (a) H&E, 100x; (b) cytology, 1000x; (c) CD3, 100x; (d) TdT, 100x.
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fig5
TdT+, CD4+/8+, CD7+ (Figure 5).
Patient 2: (a) flank mass with PTCL, H&E, 100x; (b) flank mass, TdT immunoperoxidase, 200x; (c) pleural fluid cytospin cytology, 500x.
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fig6
PTCL (Figure 6). Pleural fluid analysis showed involvement by