PMC8554308_01
(A) Brain echo at 3 days of age. Bilateral intraventricular and intracranial hemorrhage with ventricular enlargement and midline shift to the right. The arrow indicates the blood clot involved in the left ventricle (Grade 3). (B) Brain echo at 16 days of age. Hemorrhage resolved after the 14-day replacement therapy. Image shows post-hemorrhagic hydrocephalus.
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F1
Due to severe ICH, treatment with recombinant activated factor VII was provided with high-dose replacement therapy (30 mug/kg/dose Q3H) until hemorrhage resolved on sonography, which took 2 weeks (Figure 1B).
PMC8554308_02
(A) Brain echo at 3 days of age. Bilateral intraventricular and intracranial hemorrhage with ventricular enlargement and midline shift to the right. The arrow indicates the blood clot involved in the left ventricle (Grade 3). (B) Brain echo at 16 days of age. Hemorrhage resolved after the 14-day replacement therapy. Image shows post-hemorrhagic hydrocephalus.
fped-09-755121-g0001.jpg
PMC8554308_02_fped-09-755121-g0001.jpg
F1
Due to severe ICH, treatment with recombinant activated factor VII was provided with high-dose replacement therapy (30 mug/kg/dose Q3H) until hemorrhage resolved on sonography, which took 2 weeks (Figure 1B).
Sonography at 43 days of age. Hemothorax detected by chest sonography after first discharge without prophylaxis. Image shows the accumulation of clear fluid in the right pleural cavity under infra-hepatic view.
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PMC8554308_02_fped-09-755121-g0002.jpg
F2
Hemothorax was detected by chest sonography (Figure 2) and diagnostic tapping, followed by treatment with high-dose recombinant activated factor VII (30 mug/kg/dose Q4H).