PMC9753946_01
Gross examination revealed (A) a skin-covered soft tissue mass and (B) homogenous greyish white glistening areas on the cut section.
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f1
No heterogenous areas were identified (Figure 1).
Solitary fibrous tumor shows a proliferation of spindle cells without a characteristic pattern and hemangiopericytoma vascular pattern with (A) hematoxylin and eosin (H&E) stain, magnification x10, (B) H&E stain, magnification x40, (C) diffuse membranous immunohistochemical staining of CD34 (magnification x10), and (D) strong diffuse nuclear immunohistochemical staining of STAT6 (magnification x10).
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f2
On microscopic examination, a predominantly well-circumscribed encapsulated tumor was noted, with spindle-shaped cells arranged in a haphazard manner and ectatic vascular channels (Figures 2A and 2B). Immunohistochemically, the tumor cells showed strong diffuse positivity for CD34 (Figure 2C) and signal transducer and activator of transcription 6 (STAT6) (Figure 2D).