PMC6528137_01
The histological appearance of ENKL in case 1.. (A) The infiltration of lymphoma cells in the nasal cavity (HE 400x).. (B), (C), (D), (E) The immunohistochemical analysis of CD 3 (400x), CD 20 (400x), TIA-1 (400x) and EBER (400x). The immunohistochemical analysis demonstrated positivity for CD 3, TIA-1 and EBER, and negativity for CD 20.
jslrt-59-34-g001.jpg
PMC6528137_01_jslrt-59-34-g001.jpg
f1
PET-CT before treatment.. PET-CT was performed after the biopsy of the nasal tumor. Accumulation of FDG was noted in the mesenteric nodes, mediastinal nodes, pleura and pelvic mass.
jslrt-59-34-g002.jpg
PMC6528137_01_jslrt-59-34-g002.jpg
f2
In order to observe the spread of the lesions, positron emission tomography-computed tomography (PET-CT) was performed after the biopsy, and the accumulation of 18F-fluorodeoxy glucose (FDG) was observed in the mediastinal nodes, pleura, mesenteric nodes, uterus (bulky mass) and pelvic nodes (Figure 2).
The histological appearance of DLBCL in case 1.. (A) Infiltration of lymphoma cells in the uterine cervix (HE 400x).. (B), (C), (D), (E), (F) The immunohistochemical analysis of CD 3 (400x), CD 20 (400x), BCL-6 (400x), EBER (400x) and MIB-1 (400x). The immunohistochemical analysis demonstrated positivity for CD 20, BCL-6 and MIB-1, and negativity for CD 3 and EBER.
jslrt-59-34-g003.jpg
PMC6528137_01_jslrt-59-34-g003.jpg
f3
These cells were CD 10 (+), CD 20 (+), bcl-2 (+), bcl-6 (+), MUM-1 (-), EBER-ISH (-) and MIB-1 (+) (MIB-1 index; 90%) (Figure 3).