PMC9941615_01
PMC9941615_02
low-grade appendiceal mucinous neoplasia: cystic dilatation of the appendix tip lined by a well differentiated mucinous epithelium with flat and tubulous architecture associated with atrophy of the lymphoid tissue; the muscularis propria and the subserosa tissue were not infiltrated (HEx20)
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F1
Appendix examination objectified the co-existence of two independent tumors located in the tip, without transitional changes: the first tumor consisted of a LAMN classified as pTis (Figure 1).
neuroendocrine tumor: granular cytoplasmic positivity to chromogranin (immunohistochemistry, x20)
PAMJ-43-161-g002.jpg
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F2
The NET tumor cells displayed granular cytoplasmic positivity to chromogranin A and synaptophysin (Figure 2, Figure 3).
neuroendocrine tumor: granular cytoplasmic positivity to synaptophysin (immunohistochemistry, x20)
PAMJ-43-161-g003.jpg
PMC9941615_02_PAMJ-43-161-g003.jpg
F3
The NET tumor cells displayed granular cytoplasmic positivity to chromogranin A and synaptophysin (Figure 2, Figure 3).