PMC10010164_01
Postoperative pathology of gastric carcinoma in 2015.
fonc-13-1105080-g001.jpg
PMC10010164_01_fonc-13-1105080-g001.jpg
f1
The postoperative histopathology of the primary lesion was mixed invasive adenocarcinoma, of which signet-ring cell carcinoma accounted for 80%, and tubular adenocarcinoma accounted for 20% ( Figure 1 ).
Cutaneous metastatic carcinomas. (A) Beaded mass in left groin area and erythematous scleroderma of the left thigh; (B, C) Two fleshy masses on the scalp.
fonc-13-1105080-g002.jpg
PMC10010164_01_fonc-13-1105080-g002.jpg
f2
A physical examination revealed moderate pitting edema of the left lower extremity, redness and swelling of the thigh with scleroderma-like changes, bead-like nodules of about 5*20cm in the groin area ( Figure 2A ), and two fleshy masses of about 3*3cm in size on the scalp ( Figures 2B, C ).
Skin biopsy of the groin mass; the pathology showed metastatic poorly differentiated carcinoma, some of which were signet-ring cell carcinoma.
fonc-13-1105080-g003.jpg
PMC10010164_01_fonc-13-1105080-g003.jpg
f3
A skin biopsy was performed on the groin mass, and the pathology showed metastatic poorly differentiated carcinoma, some of which were signet-ring cell carcinoma; immunohistochemical staining showed: PCK(+), CK7(+), CK20(-), CDX2(+), SATB2(-), and HER2(0) ( Figure 3 ).
PET-CT examination. (A) Multiple humus-like hypodense nodules on the skin surface from the left groin to the thigh, secondary lymphedema, and slightly increased metabolic diffusion; (B) Localized thickening of the skin on the top of the left head and back of the neck and slightly increased metabolism.
fonc-13-1105080-g004.jpg
PMC10010164_01_fonc-13-1105080-g004.jpg
f4
A whole-body PET-CT examination showed multiple humus-like hypodense nodules on the skin surface from the left groin to the thigh, secondary lymphedema, and slightly increased metabolic diffusion ( Figure 4A ). The above suggested the possibility of malignant tumor metastatic lesions ( Figure 4B ).