PMC5079237_01
Abdominal CT, A (axial section) and B (coronal section) indicated wall thickening at the fundus of the gallbladder, which was well contrasted, and no abnormalities of the biliary tract or surrounding lymph nodes.
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A; Abdominal US showed wall thickening of the fundus and a well-defined margin of the gallbladder. B; MRI showed no abnormal findings at the body to neck of the gallbladder and common bile duct.
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Additionally, abdominal US showed wall thickening of the fundus and a well-defined margin of the gallbladder (Fig. 2A). Magnetic resonance imaging (MRI) showed no abnormal findings at the body to neck of the gallbladder and common bile duct (Fig. 2B).
A and B; Macroscopic findings showed wall thickening of the fundus of the gallbladder, and a normal mucosal layer of the body to neck.
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P53 protein expression was observed in the cancer cells (Fig. 3B) and in the epithelium of the peritumor to the cystic duct (Fig. 4D), which were diagnosed as normal on HE staining (Fig. 4C).
A; GBC was diagnosed as well-differentiated carcinoma, (HE x40), B P53. Protein expression was observed in the cancer cells (x40), C; the epithelium of the peritumor to the cystic duct were diagnosed normal on HE staining (x100) D; TP53 expression was observed at peritumor epithelium to cystic duct. (x100).
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The GBC was diagnosed as well-differentiated carcinoma (Grade 1) (Fig. 4A) measuring 4 x 3 cm, with transmural invasion (T2) and no lymph node metastases (N0) indicating stage II of AJCC criteria. P53 protein expression was observed in the cancer cells (Fig. 3B) and in the epithelium of the peritumor to the cystic duct (Fig. 4D), which were diagnosed as normal on HE staining (Fig. 4C).
MRCP showed dilated hepatic duct and irregular stenosis of bile duct.
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And Magnetic Resonance Cholangiopancreatography (MRCP) showed dilated hepatic duct and irregular stenosis of bile duct (Fig. 5).