PMC5813718_01
Anesthetic chart. Double circle marks represent start/end of surgery; cross marks represent start/end of anesthesia; a triangle mark represents endtracheal intubation
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PMC5813718_01_40981_2016_72_Fig1_HTML.jpg
Fig1
The anesthetic chart, with a focus on hemodynamic parameters and vasoactive drugs, is presented in Fig. 1.
Hemodynamic responses to bolus doses of NAD and AVP. a, b Representative responses of blood pressure to bolus doses of NAD (a) and AVP (b). c, d Changes in blood pressure before and after bolus doses of NAD (c) and AVP (d). Blood pressure (PAP or SAP) just before the administration of NAD or AVP was considered the baseline level. The peak blood pressures within 3 min after the administration of NAD or AVP were obtained. Horizontal lines represent mean values. NAD noradrenaline, AVP arginine vasopressin, PAP pulmonary arterial pressure, SAP systemic arterial pressure
40981_2016_72_Fig2_HTML.jpg
PMC5813718_01_40981_2016_72_Fig2_HTML.jpg
Fig2
Figure 2 shows the patient's hemodynamic responses to bolus doses of NAD and AVP administered from the time of clamping of the pulmonary artery until reperfusion. The bolus administration of NAD increased systolic SAP by 14.8% relative to that immediately before administration; in addition, it increased systolic PAP by 6.7% relative to pretreatment values (Fig. 2a, c). The bolus administration of AVP also increased systolic SAP by 35.2%; however, it affected PAP only minimally, resulting in a significant decrease in the PAP/SAP ratio from 0.87 to 0.65 (Fig. 2b, d). 