PMC3132663_01
PMC3132663_02
PMC3132663_03
(a) Perihilar segmental sclerosis (PAS, original magnification 20x). (b) Diffuse tubulopathy: variably size tubular profiles, hypertrophic tubular epithelial cells, cytoplasmic vacuolization, and coarse fuchsinophilic cytoplasmic accumulations (trichrome, original magnification 20x). (c) Diffuse tubulopathy: tubular epithelial cell cytoplasmic irregular waxy brown-yellow ceroid-lipofuscin:like pigment accumulations (black arrow) (PAS, original magnification 40x).
IJN2011-324916.001.jpg
PMC3132663_03_IJN2011-324916.001.jpg
fig1
No arteriosclerosis was present, and no vascular inflammatory lesions were present, Figures 1(a)-1(c).
Fenestrated endothelium, intact glomerular basement membranes, and infrequent podocyte foot process effacement (transmission electron microscopy, original magnification 6000x).
IJN2011-324916.002.jpg
PMC3132663_03_IJN2011-324916.002.jpg
fig2
Electron microscopy (Figure 2) revealed no capillary wall or mesangial immune complex-type electron-dense deposits.