PMC5832180_01
(a) Sonogram of both testes: sagittal view showing grossly enlarged right testis in comparison with the left. (b) T2-weighted MRI of the abdomen with contrast, transverse, and (c) sagittal views; renal cell carcinoma (red asterisk) noted on the right native kidney.
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Magnetic resonance imaging with contrast showed a small enhancing right renal nodule suspicious for cortical malignancy but there was no evidence of metastatic disease (Figures 1(b) and 1(c)).
Section of the right testis stained with hematoxylin and eosin. (a) Low power (2x) shows diffuse infiltration of the testis by large neoplastic cells. There is geographic necrosis. (b) Higher magnification (40x) shows the large cells with irregular nuclei, vesicular chromatin, and prominent nucleoli. Occasional mitoses and apoptotic bodies present.
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Histological analysis of the right testis revealed a monomorphic posttransplant lymphoproliferative disorder: diffuse large B-cell lymphoma (DLBCL) (Figure 2).
Histopathological findings of the monomorphic posttransplant lymphoproliferative disorder; diffuse large B-cell lymphoma of the right testis. Immunophenotyping, via immunohistochemistry, revealed neoplastic cells positive for Bcl-2 (a), Bcl-6 (b), Ki-67 (proliferation index > 90%) (c), and CD20 (d). Magnification for all panels: 40x.
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Immunohistochemistry of the abnormal B-cells was positive for CD20, Bcl-2, Bcl-6, MUM1, Ki-67 (at least 90%), and EBV latent membrane protein 1 (EBV LMP-1) (Figure 3).