PMC8543711_01
Pre-treatment microlaryngoscopy and microlaryngoscopy 1 year after completion of
treatment (left and right, respectively).
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Intraoperative findings included multiple non-obstructive papillomatoid lesions of the supraglottis, vocal cords and subglottis, as well as an atypical circumferential lesion extending from subglottis to 3 cm from the carina (Figure 1). Restaging PET 10 weeks following completion of chemoradiotherapy demonstrated marked reduction of metabolic activity in the primary site and no new nodal disease or distant metastatic disease (Figure 1). SCC (Figure 1). Subsequent to this, he required 3-6-weekly balloon dilation for worsening stridor associated with his airway stenosis.
Axial PET/CT, pre-treatment and 10 weeks after completion of treatment (left and right,
respectively).
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SCC arising on a background of squamous papilloma. Staging positron-emission tomography (PET) demonstrated intense FDG avidity associated with the circumferential tracheal mass (Figure 2) but no evidence of nodal or distant metastases.
Radiation dosimetry.. Red line denotes the PET avid disease, blue denotes 60 Gy, and green denotes 56 Gy
(prophylactic nodal coverage).
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The patient commenced radiotherapy of 60 Gy over 27 fractions over 5.2 weeks (Figure 3) with high-dose cisplatin (100 mg/m2) in weeks 1 and 4.