PMC7511560_01
Clinical course of a 67-year-old man during hospitalization for severe COVID-19-induced acute respiratory distress syndrome. After initiation of corticosteroid treatment on day 20 of hospitalization, partial pressure of arterial oxygen (PaO2) gradually improved and inflammatory marker C-reaction protein (CRP) decreased. Fraction of inspired oxygen (FiO2) of the ventilator was set at 1.0 before extracorporeal membrane oxygenation (ECMO) deployment. During and after ECMO support, FiO2 was set at 0.4. CEZ, cefazolin; CRP, C-reaction protein; CRRT, continuous renal replacement therapy; FER, ferritin; IL-6, interleukin-6; LVFX, levofloxacin; LZD, linezolid; MEPM, meropenem; m-PSL, methylprednisolone; PIPC, piperacillin; PSL, prednisolone; TAZ, tazobactam; VV-ECMO, veno-venous ECMO.
AMS2-7-e569-g001.jpg
PMC7511560_01_AMS2-7-e569-g001.jpg
ams2569-fig-0001
The patient's clinical course during hospitalization is shown in Figure 1.
Chest computed tomography (CT) and chest X-ray images in time series of a 67-year-old man during hospitalization for severe COVID-19-induced acute respiratory distress syndrome. A, Chest CT on day 1 shows bilateral basal consolidation with peripheral ground-glass opacity. B, Chest X-ray on day 1 shows bilateral pulmonary infiltrate mainly in hilar region. C, Chest X-ray on day 20 shows bilateral diffuse pulmonary infiltrates with air bronchogram. D, Chest X-ray on day 23 shows improved bilateral lung opacity (mainly in the right lobe of lungs). E, Chest X-ray on day 31 (extracorporeal membrane oxygenation removed). F, Chest X-ray on day 52 (ventilator removed).
AMS2-7-e569-g002.jpg
PMC7511560_01_AMS2-7-e569-g002.jpg
ams2569-fig-0002
On day 23, lung opacity on chest X-ray and oxygen saturation improved significantly (Fig. 2).