PMC8249753_01
Development of ICI-related pneumonitis in a patient treated with pembrolizumab for lung adenocarcinoma. (A, B) Chest CT images showed the lesions in the upper lobe of the right lung before treatment (May 17, 2020). (C-E) After 3 cycles of immunotherapy, CT images showed that primary lesions were stabilized, but pneumonitis in the left lung (July 24, 2020). (F-H) CT images showed obvious improvement of pneumonitis (July 29, 2020).
fonc-11-673877-g001.jpg
PMC8249753_01_fonc-11-673877-g001.jpg
f1
However, chest computed tomography (CT) scan in May 2020 showed a mass in the upper lobe of the right lung ( Figures 1A, B ). A repeat chest CT scan showed multiple patchy and striped shadows in the left lung on July 24 ( Figures 1C-E ), and stable disease (RECIST criteria) of primary tumor lesion was evaluated. Five days later, his clinical condition greatly improved, with obvious radiological improvement in the left lung and stable primary tumor lesion on follow-up CT ( Figures 1F-H ).