PMC6243292_01
Anterior nasal endoscopic view of the right nasal cavity demonstrating a mass protruding through the anterior nasal cavity (arrow) in the anatomical space of the middle turbinate. The nasal septum is visualized medially (star).
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Clinical examination demonstrated a hard mass protruding through the right nostril (Figure 1).
A 31-year-old female patient presenting with nasal block. (a) Non-contrast-enhanced coronal CT images demonstrate a minimally thickened middle turbinate (arrow). (b) The axial image demonstrates extensive areas of heterogeneous calcification in the mid-nasal cavity (open arrow), extending anteriorly to the right nasal vestibule. (c) Parasagittal CT reconstruction demonstrates the lesion extending to the basal lamella (triangle).
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The lesion was occupying most of the mid-nasal cavity by displacing the inferior turbinate and extending into the nasal vestibule (Figure 2).
Haematoxylin and eosin-stained photomicrograph (a) shows isolated trabeculae of woven bone without osteoblastic rimming and intervening cellular fibrous tissue comprising benign spindle to polygonal cells with no atypical features. (b) Additional photograph demonstrates sheets of mature bone separated by focal cellular areas with formation of fibrous and hyaline cartilage nodules.
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Microscopic evaluation demonstrated features suggestive of a benign fibro-osseous lesion, favouring FD (Figure 3).
PMC6243292_02
A 32-year-old adult female with occasional nasal bleeding. (a) Coronal CT image at the mid-nasal cavity level demonstrates thickening of the orbital plate and zygomatic bone. There is massive thickening of the lateral lamella and middle turbinate (arrow), encroaching upon the superior aspect of the left nasal cavity. (b) Axial image demonstrates an enlarged superior turbinate showing posterior continuity with the skull base (arrow), demonstrated better on the sagittal CT reconstruction (triangle; c).
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There was gross homogeneous enlargement of the lateral and basal lamella of the middle turbinate (Figure 4).