PMC5411392_01
High-power view of a section of the terminal ileum, demonstrating active ileitis. Findings are indicative of acute ileitis, but non-specific for Crohn's disease
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F1
Histological evidence of acute ileitis was present (Fig. 1), but again there were no signs of chronicity.
Endoscopic examination of the ileum, demonstrating mucosal edema and erythema with multiple aphthoid ulcers
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F2
Repeat endoscopy (Fig. 2) revealed mucosal edema and erythema with several aphthoid ulcers.
Medium-power view of a section of the terminal ileum, demonstrating active ileitis with signs of chronicity, including crypt architectural distortion and pyloric gland metaplasia. These findings, in combination with the patient's clinical picture, are strongly suggestive of Crohn's disease
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F3
The pathology (Fig. 3) was consistent with chronic ileitis, including pyloric gland metaplasia and moderate crypt distortion, highly suggestive of Crohn's disease.