PMC6556355_01
MRI of the brain was done which revealed 4 masses with 2 dominant mass lesions (6.0 and 4.5 cm) having irregular lobulations in the bilateral temporal lobes consistent with metastatic disease.
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fig1
MRI of the brain revealed 4 masses including 2 dominant mass lesions (6.0 and 4.5 cm) having irregular lobulations in the bilateral temporal lobes consistent with metastatic disease (Figure 1).
(a) Neoplastic cells forming papillary clusters with smooth contoured edges (b) Serous borderline tumor with hierarchically branched papillae lined by polygonal to columnar serous epithelium with mild atypia (inset) Immunohistochemistry showed (c) CK7 cytoplasmic positivity (d) PAX8 diffuse nuclear positivity (e) WT-1 diffuse nuclear positivity (f) CK20 negative staining.
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fig2
The fluid sample from the current cystic mass in the brain revealed neoplastic cells forming papillary clusters with smooth contoured edges on the smear (Figure 2(a)). Tissue sample of the brain lesion showed clusters of broad papillae with hierarchical branching and is lined by polygonal to columnar serous epithelium with mild to moderate atypia (Figure 2(b)). Immunohistochemical staining shows positive staining for PAX 8, WT-1, and CK7 and negative staining for CK20 (Figures 2(c)-2(f)).