PMC7034788_01
Chest X-ray showing heterogeneous opacity in the left upper lung zone with reticulonodular opacity in bilateral lung
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F1
The chest X-ray demonstrated heterogeneous opacity in the left upper lung zone with reticulonodular opacity in the bilateral lung zones (Figure 1).
Capsulated gram positive budding yeast cells in blood culture
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F2
Variable sized (5-10 microm) encapsulated narrow-based budding yeast-like cells were seen in direct smear (Figure 2A). India ink preparation of blood culture sample aspirated from culture bottle showed budding yeast cells with a clear halo (Figure 2B).  Creamy mucoid colonies were obtained in blood agar and Sabouraud dextrose agar after 48 h of aerobic incubation (Figure 2C). The serum sample of the patient was also positive for lateral flow immunochromatographic test for cryptococcal antigen (CryptoPS, Biosynex, France) (Figure 2D).