PMC10332927_01
Peripheral blood and bone marrow evaluation. (a) The peripheral blood smear showed circulating blasts (arrow, Giemsa and Wright stain x100). (b) The bone marrow biopsy was hypercellular (H & E x 20) with moderate myelofibrosis, (c) confirmed by reticulin stain (x40). (d-f) The blasts are positive for CD34, CD117, and CD71 (x40), which are suggestive for erythroid lineage. (g, h) Moreover, the blasts are negative for myeloperoxidase and positive for CD43 (x40) (i) with aberrant expression of PAX5 (x40).
CRIHEM2023-9771388.001.jpg
PMC10332927_01_CRIHEM2023-9771388.001.jpg
fig1
Auer rods (Figure 1(a)). A bone marrow biopsy demonstrated hypercellularity (~90%), diffuse proliferation of blasts (Figure 1(b)), and moderate myelofibrosis confirmed by reticulin stain (Figure 1(c)). The blasts showed aberrant expression of PAX5 (Figures 1(d)-1(i)).