PMC4533487_01
Computed tomography at the first consultation showing right frontal lobe intracerebral hemorrhage.
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F1
Computed tomography (CT) showed right frontal lobe intracerebral hemorrhage (Fig. 1). Contrast-enhanced magnetic resonance (MR) imaging showed an unremarkable enhanced intraaxial mass with slight perifocal edema appearing to be acute hematoma, but the possibility of hemorrhagic metastasis could not be rejected (Fig. 2).
A: Axial T1-weighted magnetic resonance (MR) imaging showing an acute hematoma in the right frontal lobe. B-D: Gadolinium-enhanced T1-weighted MR imaging showing no markedly enhanced lesion.
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F2
Computed tomography (CT) showed right frontal lobe intracerebral hemorrhage (Fig. 1). Contrast-enhanced magnetic resonance (MR) imaging showed an unremarkable enhanced intraaxial mass with slight perifocal edema appearing to be acute hematoma, but the possibility of hemorrhagic metastasis could not be rejected (Fig. 2).
Photomicrographs of the resected specimen of the hematoma showing epithelioid cells surrounded red blood cells (A: hematoxylin and eosin stain x200). Epithelioid cells positive for AE1/AE3 (B: cytokeratin AE1/AE3 antibody stain x200) and negative for CD5 and CD117 (not shown).
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F3
Pathological findings revealed a small quantity of epithelioid cells inside the hematoma (Fig. 3A). Immunohistochemical studies showed that these cells were positive for keratin (Fig. 3B) and negative for CD5 and CD117 (not shown), which were useful for differential diagnosis of thymoma or thymic carcinoma.