PMC4877140_01
Patient's computed tomography of chest indicating (A) baseline CT scan before pembrolizumab therapy, (B) reverse halo sign (dotted arrow) and consolidation with air bronchogram (straight arrow) features of OP following therapy of pembrolizumab, and (C) follow-up CT scan indicating complete resolution of the organized pneumonia, one month after the steroid therapy. Metastatic lesion in the right middle lobe.
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The HRCT demonstrated patchy consolidation with a predominantly subpleural and peribronchial distribution, small ill-defined peribronchiolar nodules, tree-in-bud sign, and reverse halo sign, involving all lobes mainly the lower ones (Fig. 1).