PMC3936157_01
Axial CT scan of the abdomen and pelvis without contrast. A, B. Diffuse thickening of the urinary bladder wall (arrows) with surrounding fat streaking of the pelvis. A pocket of gas is noted C, D. Mild right hydroureteronephrosis (arrowheads).
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Workup included a computed tomography (CT) scan of her abdomen and pelvis, which showed diffuse thickening of the urinary bladder wall with surrounding fat streaking of the pelvis and retroperitoneum (Figure 1). There was evidence of mild right hydroureteronephrosis with no evidence of obstructing urinary tract calculi (Figure 1).
A. H&E sections of the urinary bladder biopsy revealing a dense submucosal infiltrate (mag. 40x). B. The cells are cohesive, plasmacytoid with an abundant eosinophilic cytoplasm and eccentric nucleus (mag. 400x). The cells demonstrate positive immunostaining with anti-estrogen receptor (ER) antibody (C, mag. 400x) and anti-cytokeratin-7 (CK-7) antibody (D, mag. 200x).
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This is consistent with breast ductal carcinoma (Figure 2).