PMC9893423_01
Clinical photography of the sacral mass.
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F1
In the prone position, we noticed the presence of an excrescence slightly deforming the left hemisacrum (Fig. 1).
Cystomanometric study. During the filling phase, uninhibited detrusor contractions were observed. The intravesical pressure rised to 40 cm H2O. This lower bladder compliance (Compliance= 8.33 ml /cm H2O) was associated with a reduced capacity.
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F2
The cystometry objectified a low-compliant and overactive bladder (Fig. 2).
MRI showing a tumor mass (red circle) centered on the sacrum, which is lobulated, well-circumscribed (a: sagittal MRI) with hyperintense T2 signal (b: axial MRI).
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F3
MRI revealed a large osteolytic tumor centered on the sacrum and associated with intracanal extension (Fig. 3).
Pathologic aspect of sacral chordoma. (A) Tumor cells are organized in masses and cords. They are separated from chondromyxoid matrix by fibrous septa (black arrow). (Hematoxylin & eosin, HE x 40). (B) Epithelioid cell (red arrow): the cytoplasm is eosinophilic and contains more than one nucleus. Physaliphore cell (green arrow) has multivacuolar cystoplasm (Hematoxylin & eosin, HE x 200).
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F4
The nuclei are rounded and monomorphic with focal cytoplasmic pseudoinclusions (Fig. 4).