PMC6557966_01
Spleen tissue biopsy, infiltration of red pulp cords, sinusoids
and scattered residual white pulp islands by sheets of pleomorphic
large cells resembling popcorn cells
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F1
Neither granuloma nor necrosis was observed (Figure 1).
Spleen tissue biopsy, positive for CD20
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F2
Spleen tissue biopsy, positive for CD3
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F3
Spleen tissue biopsy, positive for BCL-2
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F4
Spleen tissue biopsy, positive for CD30
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F5
Spleen tissue biopsy, positive for CD34
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F6
Spleen tissue biopsy, negative for CD15
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F7
Spleen tissue biopsy, negative for EMA.
Bone marrow Biopsy revealed thin anastomosing bony trabeculae separating 15 hematopoietic spaces with normal cellularity (60%)(3/5)(Figure 9)
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F8