PMC5806283_01
Non-contrast (A, B) and contrast-enhanced (C, D) CT images. The mass was located lateral to the genioglossus and hypoglossus muscles and the submandibular gland was compressed and inferiorly displaced (arrow). Contrast-enhanced CT demonstrated enhancement of intratumoral blood vessels.
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F1
No evidence of cystic or necrotic degeneration was present in the CT (Fig. 1).
MR images showed homogeneous isointensity on T1-WI (A), heterogeneous hypointensity on T2-WI (B), heterogeneous hyperintensity on STIR (C), and heterogeneous enhancement on contrast-enhanced T1-WI (D). A clear capsule was observed on the margin (arrow).
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F2
T2-WI. The submandibular gland was compressed and displaced inferiorly (Fig. 2).
Dynamic MRI showed heterogeneous gradual increased enhancement. Regions of gradual increased enhancement were observed (red arrows).
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F3
The uptake of contrast medium was regionally slow (Fig. 3).
A: Intraoperatively, the tumor was well-encapsulated and continuous with the hypoglossal nerve (arrow). B, C: No cystification or necrosis degeneration was observed from the macroscopic features.
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F4
Intraoperatively, the tumor was well-encapsulated and continuous with the hypoglossal nerve (Fig. 4).
Histopathologic examination of the surgical specimen demonstrated a central mucous matrix and the surrounding nerve axon. Indicates Antoni type A of intermediate power field (A) and Antoni type B of intermediate power field (B). Each high power fields are (C) and (D). Antoni type A is composed of spindle shaped Schwann cells with elongated nuclei arranged in streams and nuclear palisades known Verocay bodies (arrow). Antoni type B consists of less spindle cells and have a myxoid background.
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A and Antoni type B (Fig. 5). Antoni type A is composed of spindle shaped Schwann cells with elongated nuclei arranged in streams and nuclear palisades known Verocay bodies. Antoni type B consists of less spindle cells and a myxoid background.