PMC9994445_01
Representative case description of docetaxel-induced lower limb edema in Stage IV breast cancer. CTCAE, Common Terminology Criteria for Adverse Events; NPE, nonpitting edema.
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A 60-year-old female participant with stage IV BC enrolled for this study (Fig. 1).
Initial findings of lower limb edema with docetaxel of ultrasonic images of 15 cm below the fibula head.
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IV and non-stage IV BC patients, CTCAE and pitting test showed that lower limb edema developed after the administration of the fourth dose of docetaxel (Table 2). In addition, the pitting test confirmed that ultrasonographic findings such as uneven lower edge of skin dermis and blurring of the border between the dermis and subcutaneous tissue appears before edema in both stage IV and non-stage IV BC patients (Fig. 2).
Findings in the lower limbs of patients who did not develop edema of ultrasonic images of 15 cm below the fibula head.
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Moreover, the superficial fascia was flat in the subcutaneous tissue (Fig. 3).