PMC4317201_01
Clinical image of the breasts revealing a large left breast mass.
ccr30003-0007-f1.jpg
PMC4317201_01_ccr30003-0007-f1.jpg
fig01
The overlying skin was bluish-purple in color, with a lateral deviation and distortion of the nipple (Fig.1).
(A) Mammogram (medial-lateral oblique view) of the left breast demonstrating a large central breast mass. (B) Ultrasound with color doppler of the solid, vascular portion of the left breast mass. (C) MR image of the left breast mass demonstrates the large cystic portion and one of the enhancing solid portions of the complex mass.
ccr30003-0007-f2.jpg
PMC4317201_01_ccr30003-0007-f2.jpg
fig02
Diagnostic mammography revealed a large mass in the left breast and a few scattered coarse calcifications (Fig.2A). Ultrasound examination demonstrated a complex vascular mass with a large homogenous fluid component occupying the majority of the left breast with features suspicious of malignancy (Fig.2B). Bilateral MRI was performed to further characterize the mass, revealing a 13 x 11 x 13 cm mass with both cystic and enhancing solid components abutting the chest wall and the lateral aspect of the mass demonstrating skin involvement (Fig.2C).
H&E 40 x 5 - high magnification view of core biopsy sample demonstrates apocrine atypia.
ccr30003-0007-f3.jpg
PMC4317201_01_ccr30003-0007-f3.jpg
fig03
Both revealed sclerosing papilloma with focal usual ductal hyperplasia and minimal focal cytologic apocrine atypia (Fig.3).
H&E 10 x 3 - low magnification view of mastectomy sample demonstrates papilloma.
ccr30003-0007-f4.jpg
PMC4317201_01_ccr30003-0007-f4.jpg
fig04
The mastectomy specimen was finely sliced at 4-5 mm intervals throughout and the firm areas were submitted for microscopic examination (Fig.4).