PMC9876007_01
Left colon with erythema, loss of vascularity, and exudates.
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F1
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).
Discrete shallow ulcers at the rectosigmoid junction.
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F2
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).
Photomicrograph of colonic mucosa with edematous lamina propria (black arrow), acute and chronic inflammatory cell infiltrate (green arrow), and neutrophilic cryptitis (yellow arrow).
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F3
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).
Higher magnification showing crypts with crowded enlarged nuclei with mucin loss (red arrows), mitotic figure (blue arrow), and apoptotic bodies (green arrow).
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F4
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).
Negative cytomegalovirus stain.
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PMC9876007_01_ac9-10-e00974-g005.jpg
F5
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).
Contrast-enhanced computed tomography demonstrating partially collapsed descending and sigmoid colon with mild wall thickening.
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PMC9876007_01_ac9-10-e00974-g006.jpg
F6
She reported complete resolution of symptoms on holding brentuximab from the AAVD regimen and did not experience recurrence with the following cycles (Figures 1-6).