PMC9883731_01
Medications' schedule of patient at admission.
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Daily schedule of medications at admission is shown in Figure 1.
Dabigatran peak and trough concentrations before and after levetiracetam administration delay.
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Table 2): for these reasons, we decided to measure plasmatic concentrations of dabigatran by evaluating anti-IIa levels. Blood samples were collected at dabigatran peak concentration (2 h post-intake) and trough (immediately before next intake), after 10 days from the beginning of therapy. The trough plasma concentration of dabigatran was in the normal range provided by the lab (61-143 ng/mL), while peak concentrations were below range (117-275 ng/mL) (Figure 2). Indeed, dabigatran peak concentration increased from 88 to 101 ng/mL (Figure 2).