PMC6889700_01
a Clinical picture of penile ulcerative nodule on glans penis. b Photomicrograph : H&E stain: Bundles of proliferating spindle cells wild mild atypia & foci of sprinkled RBC's. c CD34 Immunostain: Cytoplasmic staining of spindle cells as well as endothelial cells of capillaries indicating spindles cells of endothelial origin. d HHV-8 immunostain: Demonstrates nuclear positivity to HHV-8 LNA-1 confirming Kaposi's sarcoma
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PMC6889700_01_13027_2019_261_Fig1_HTML.jpg
Fig1
Local examination revealed an ulcerated firm, reddish brown, slightly tender nodule of 8 mm. on glans penis near corona on the ventral aspect of the penis (Fig. 1a).  The immunostains revealed the spindle cells were immunoreactive for CD31, CD34 &HHV8 LANA-1 and non-reactive for SMA. (Fig. 1b, c, d); consistent with Kaposi sarcoma.