PMC4327402_01
CT scans. a The tumor has spread into the deep bladder wall layer. b The arrow indicates external iliac lymph node swelling.
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F1
Computed tomography (CT) showed thickening and irregularity of the whole bladder, with left external iliac lymph node metastasis (fig. 1).
Pathological findings. a The tumor cells have a clear nuclear body and karyomitosis. They show a syncytial pattern and are surrounded by infiltrated lymphocytes. Hematoxylin-eosin staining. x400. b The tumor cells and stromal lymphocytes are not stained by EBER1. Immunohistochemical staining. x400. c The stromal lymphocytes are stained by CD3. Immunohistochemical staining. x100. d The tumor cells are stained by cytokeratin AE1/AE3. Immunohistochemical staining. x200.
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F2
The infiltrating lymphocytes were stained by CD3 and CD20 (fig. 2).