PMC545046_01
Low power photomicrograph of the phyllodes tumor: Histologically, the neoplasm was biphasic, with proliferating stroma, compressed glands, and a well developed leaf-like architecture (H&E, original magnification 40x).
1477-7819-2-46-1.jpg
PMC545046_01_1477-7819-2-46-1.jpg
F1
The features were consistent with a benign phyllodes tumor (figures 1 &2).
High power photomicrograph of the phyllodes tumor: The stroma lacked cellular atypia and mitoses, consistent with a benign phyllodes tumor (H&E, original magnification 400x).
1477-7819-2-46-2.jpg
PMC545046_01_1477-7819-2-46-2.jpg
F2
The features were consistent with a benign phyllodes tumor (figures 1 &2).
Photomicrograph of the carcinomatous component: The epithelial component showed DCIS and invasive mammary carcinoma (H&E, original magnification 100x).
1477-7819-2-46-3.jpg
PMC545046_01_1477-7819-2-46-3.jpg
F3
More importantly, the epithelial component of the phyllodes tumor showed extensive ductal carcinoma in-situ, with multiple foci of invasive mammary carcinoma (figure 3).
Photomicrograph of the DCIS patterns: The DCIS showed cribriform and micropapillary architecture, with necrosis (H&E, original magnification 100x).
1477-7819-2-46-4.jpg
PMC545046_01_1477-7819-2-46-4.jpg
F4
The DCIS was of high nuclear grade, cribriform and micropapillary architecture, with (comedo-type) necrosis (figure 4).