PMC9744074_01
Computed tomography scan intraluminal polypoidal mass leading to near complete luminal obstruction that involving cervical and upper thoracic esophagus associated with invasion to the posterior aspect of the trachea, mediastinal lymphadenopathy
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F1
In computed tomography (CT) scan, increase in esophageal thickness reported in entire of its length [Figure 1].
Neoplastic cells infiltrated in the esophageal wall. (a) x100. (b) x400
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F2
Several biopsies undertaken and prepared slides revealed neoplastic proliferation of small tumoral cells with high N/C ratio, pleomorphism, and marked mitotic activity with necrosis [Figure 2].
Immunohistochemistry: (a) Cytokeratin. (b) neuron-specific enolase. (c) Chromogranin
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F3
Ki67 was positive in 50% of tumoral cells [Figure 3].