PMC4410898_01
Chest computed tomographic scan before treatment (A) and after 3 months' treatment (B).
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Unfortunately, 3 months previously, pulmonary metastasis was found via CT (Figure 1A). Interestingly, her restaging CT scan showed that the pulmonary metastatic lesions showed almost complete response to the treatment (Figure 1B), and her primary lung tumors and brain metastases showed stable disease.
Paronychia in left ring finger (A), papulopustular rash in right leg (B), the thicker eyebrows (C), the darker beard (D) were found, respectively.
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However, after 2 months of treatment, she developed paronychia of the right middle finger and left ring finger (Figure 2A), accompanied by onychorrhexis. Papulopustular rashes subsequently appeared on the patient's right side of the neck and right leg (Figure 2B), her eyebrows gradually became thicker and more rigid (Figure 2C), and she developed the darker beard (Figure 2D).