PMC3543950_01
(A) Chest X-ray after coronary angiogram. It shows increase of computed tomography ratio, but no active pulmonary pathology, nor bony abnormality. (B) Chest X-ray upon presentation with respiratory symptoms. Chest X-ray reveals perihilar peribronchial nodular opacities (white arrow) and diffuse ground grass opacity (black arrows).
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F1
Chest X-rays showed perihilar peribronchial nodular opacities and diffuse ground-glass opacities in both lung fields as compared with the pre-procedural chest X-ray findings (Fig. 1).
High resolution computed tomography view of the chest reveals diffuse ground-glass opacities throughout both lungs (white arrow) and centrilobular nodules (yellow arrows).
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F2
On high-resolution computed tomography, diffuse ground-glass opacity and centrilobular nodules were observed throughout both lungs (Fig. 2).
(A) Histological features of the open lung biopsy. Light micrograph of the case shows bronchial and peribronchial patchy inflammatory infiltration of lymphocytes (white arrow), and vague granuloma with multinucleated giant cells (black arrow) (H&E, x 40). (B) High magnification of Fig. 3A showing two vague granulomas (black arrows) with epithelioid macrophages (arrowhead) and multinucleated giant cells (white arrow) (H&E, x 200).
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F3
There were a few areas of vague granulomas showing multinucleated giant cells around the bronchiolar lesions (Fig. 3A and 3B).