PMC5219622_01
Overview of cases geographical data.
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Patient 1, a 47-year-old man who lived in Lousada (Fig. 1), a rural area nearby a sheep farm, was admitted with acute hepatitis in January 2014. Patient 2, a 47-year-old man from Rio Tinto (Fig. 1), who worked in an abattoir, was admitted with a history of fever in October 2014. Patient 3, a 31-year-old man who lived in a rural area in Aguas Santas (Fig. 1), with farmers in the surroundings and with no prior medical history, presented to the Emergency Department with a 4-day history of prostration, fever (maximum of 39,4  C), anorexia, nausea and one episode of vomiting. Patient 5, a 22-year-old woman who lived in an urban area in Ermesinde (Fig. 1) with sporadic contact with rural areas, and with a personal history of scoliosis and chronic rhinosinusitis, was admitted in February 2015 with a 5-day history of fever, upper abdominal pain, constipation and anorexia. Patient 6, a 72-year-old man who lived in a rural area in Porto (Fig. 1), with goats in the backyard (one of them had an abortion 3 weeks earlier), was admitted in July, 2015 with a 7 day history of fever, anorexia and malaise.