PMC6701299_01
(a) CT scan showing thyroid gland with large left lobe mass. (b) Sheets of monoclonal plasma cells infiltrating skeletal muscle fibers, H&E. (c) PET-CT showing 4.4 x 4.7 cm mass with central necrosis within the left thyroid lobe.
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CT of neck showed a left thyroid mass (7 x 5 x 7 cm) with irregular borders and a multinodular thyroid enlargement. (Figure 1(a)). Biopsy confirmed lambda-restricted plasma cell neoplasm involving the strap muscles (Figure 1(b)). Whole body FDG-PET scan showed FDG uptake in a 4.4 x 4.7 cm mass with central necrosis within the left thyroid lobe (Figure 1(c)) along with mild FDG uptake within two right breast nodules. (Figure 2(a)).
(a) PET-CT showing right breast nodules with FDG uptake. (b) Breast lesion consisting of monoclonal plasma cells, H&E. (c) Monoclonal plasma cells permeate the native breast lobules, H&E.
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fig2
Whole body FDG-PET scan showed FDG uptake in a 4.4 x 4.7 cm mass with central necrosis within the left thyroid lobe (Figure 1(c)) along with mild FDG uptake within two right breast nodules. (Figure 2(a)). Excision biopsy of the right breast nodule also showed lambda-restricted plasma cell neoplasm (Figure 2(b) and 2(c)) positive for CD 56, CD138, CD79a, and VS38C.