PMC3420753_01
FDG-PET: positive uptake of radiotracer in the right breast.
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fig1
Initial investigations included a computed tomography scans of the abdomen, thorax, and pelvis which failed to detect any further abnormality, a whole body positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) showed a positive uptake of radiotracer in the right breast suggesting a recurrent disease (Figure 1).
Neoplastic population basically formed by blasts.
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fig2
At light microscopy, a tumoral growth which diffusely infiltrated the mammary gland consisting mainly of blasts with variably shaped nuclei, multiple evident nucleoli, a rather dense chromatin and a moderate amount of cytoplasm was demonstrated (Figure 2).
CD34: intense positive immunostaining.
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fig3
Surprisingly, immunohistochemistry showed that the neoplastic cells were strongly stained for CD34 (Figure 3) and myeloperoxidase, being negative for the remaining cell markers employed CD79a, CD20, CD10, CD3, and Glycophorin A.