PMC7695903_01
Axial computed tomography scan showing gallbladder wall thickening with an indistinct border with the liver and abutment to the duodenum (white arrow) and colon (black arrow).
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To better characterize the abnormal lesion found on ultrasound, CT and MRI scans were performed; both confirmed a gallbladder mass with an ill-defined interface with the liver, raising concern for an invasive neoplastic process (Fig. 1).
Lymphohistiocytic inflammation extending from the gallbladder bed into the liver. White arrows indicate transition into the liver (tissue on left). Black arrows indicate large yellow gallstone fragments within the inflammation. 20x magnification.
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The pathology report confirmed XGC with marked lymphohistiocytic inflammatory infiltrate, multifocal abscesses, and numerous multinucleated giant cells, including Touton-type giant cells (Fig. 2).