PMC9792343_01
PET, CT and PET/CT examination findings (upper row - 17 years after orchiectomy; bottom row - 24 years after orchiectomy). Arrows point towards the enlarging cystic mass in the left retroperitoneum, near the left psoas major muscle.
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On CT measurement, the lesion had dimensions of 102 x 85 x 110 mm, part of the mass had a cystic character, the caudal part was solid and compact (Fig. 1).
Resected specimen with cystic part (black arrows) and solid part (blue arrows) after grossing. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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After surgical resection of the retroperitoneal tumor, the specimen grossly consisted of a cystic mass with greatest diameter of 12 cm, the thickness of the cyst wall was 2 mm, and a solid mass attached to the cyst from the outer wall, which was 13 cm long and 1,5 cm thick (Fig. 2).
A Markedly thickened hyalinized vessels surrounded by tumor cells (HE, 100x). B Hypercellular area (Antoni A - left) and hypocellular area with edematous stroma (Antoni B - right) separated by broad, dense connective tissue band (HE, 100x). C Spindle-shaped tumor cells with bland nuclei, without cytologic or nuclear atypia, growing in bundles in Antoni A area (HE, 400x).
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Histopathological evaluation of the mass revealed a tumor composed of spindle-shaped cells with slender nuclei, without cytologic or nuclear atypia (Fig. 3), without increased mitotic activity (Ki-67 < 5%), the cells were growing in bundles, nests, and bands. Some areas were hypercellular, composed predominantly of tumor cells (Antoni A), some areas were hypocellular with abundance of stroma (Antoni B) with edematous and myxoid appearance (Fig. 3). Vessels had a thickened, hyalinized walls, no apparent vascular invasion by the tumor cells was identified (Fig. 3).