PMC3818933_01
Demonstrates extensive carcinoma in situ of the urothelium. In the lamina propria there are a population of atypical cells with enlarged nuclei, prominent nucleoli and varying quantities of cytoplasm consistent with a plasma cell tumor.
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Further histological evaluation of this formal resection of the biopsy site and surrounding urothelium showed widespread carcinoma in situ and a population of atypical cells with enlarged nuclei, prominent nucleoli, and varying quantities of cytoplasm showing plasmacytoid features with occasional mitoses (see Figure 1).
Demonstrates a localized mass in the posterior aspect of the bladder wall which is organ confined. There is no pelvic lymphadenopathy.
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Computed tomography (CT) of brain, chest, abdomen, pelvis, and skeletal surveys revealed no metastatic spread and organ confined disease (see Figure 2).