PMC7363969_01
Images of airway secretions or mucous exudates for cases 1 and 2. (A,B) Case 1, (C) Case 2.
fped-08-00360-g0001.jpg
PMC7363969_02_fped-08-00360-g0001.jpg
F1
Biopsy was then performed (Figure 1C).
Trancheal bronchoscopy images for the three cases. (A,B) Cases 1 (A1,A2) and 2 (B1,B2) showed substantial purulent secretion and necrotic mucosa. (C) Case 3 showed necrotic mucosa during acute phase (C1) and irregularly shaped trachea and granulation during the recovery phase (C2).
fped-08-00360-g0002.jpg
PMC7363969_03_fped-08-00360-g0002.jpg
F2
On day 22, bronchoscopy was performed, which revealed substantial purulent secretion and necrotic areas throughout the tracheal mucosa (Figure 2C1). The last bronchoscopic examination during hospitalization showed tracheal stenosis and granulation (Figure 2C2).
Pathologic results of tracheal biopsy for the three cases. (A) Case 1 exhibited neutrophil infiltration and fibrinoid necrosis. (B) Case 2, it showed fibrinoid necrosis and purulent cells. (C) Case 3 demonstrated fibrinoid exudation and substantial Aspergillus load. (Hematoxylin and eosin staining, 200 x magnification).
fped-08-00360-g0003.jpg
PMC7363969_03_fped-08-00360-g0003.jpg
F3
Histologic evaluation showed inflammatory necrotic tissue and Aspergillus fumigatus infection (Figure 3C).
Imaging findings of the three cases. (A) Case 1 showed membranous material that was strongly adherent to the tracheal wall. (B) Case 2 showed inflammation in bilateral lungs. (C) Case 3 had local stenosis of right main bronchus.
fped-08-00360-g0004.jpg
PMC7363969_03_fped-08-00360-g0004.jpg
F4
Repeat CT showed local stenosis of right main bronchus (Figure 4C) and a cavity formed near the pleura in the right lower lung.
PMC7363969_02
Images of airway secretions or mucous exudates for cases 1 and 2. (A,B) Case 1, (C) Case 2.
fped-08-00360-g0001.jpg
PMC7363969_02_fped-08-00360-g0001.jpg
F1
Biopsy was then performed (Figure 1C).
Trancheal bronchoscopy images for the three cases. (A,B) Cases 1 (A1,A2) and 2 (B1,B2) showed substantial purulent secretion and necrotic mucosa. (C) Case 3 showed necrotic mucosa during acute phase (C1) and irregularly shaped trachea and granulation during the recovery phase (C2).
fped-08-00360-g0002.jpg
PMC7363969_03_fped-08-00360-g0002.jpg
F2
On day 22, bronchoscopy was performed, which revealed substantial purulent secretion and necrotic areas throughout the tracheal mucosa (Figure 2C1). The last bronchoscopic examination during hospitalization showed tracheal stenosis and granulation (Figure 2C2).
Pathologic results of tracheal biopsy for the three cases. (A) Case 1 exhibited neutrophil infiltration and fibrinoid necrosis. (B) Case 2, it showed fibrinoid necrosis and purulent cells. (C) Case 3 demonstrated fibrinoid exudation and substantial Aspergillus load. (Hematoxylin and eosin staining, 200 x magnification).
fped-08-00360-g0003.jpg
PMC7363969_03_fped-08-00360-g0003.jpg
F3
Histologic evaluation showed inflammatory necrotic tissue and Aspergillus fumigatus infection (Figure 3C).
Imaging findings of the three cases. (A) Case 1 showed membranous material that was strongly adherent to the tracheal wall. (B) Case 2 showed inflammation in bilateral lungs. (C) Case 3 had local stenosis of right main bronchus.
fped-08-00360-g0004.jpg
PMC7363969_03_fped-08-00360-g0004.jpg
F4
Repeat CT showed local stenosis of right main bronchus (Figure 4C) and a cavity formed near the pleura in the right lower lung.
PMC7363969_03
Trancheal bronchoscopy images for the three cases. (A,B) Cases 1 (A1,A2) and 2 (B1,B2) showed substantial purulent secretion and necrotic mucosa. (C) Case 3 showed necrotic mucosa during acute phase (C1) and irregularly shaped trachea and granulation during the recovery phase (C2).
fped-08-00360-g0002.jpg
PMC7363969_03_fped-08-00360-g0002.jpg
F2
On day 22, bronchoscopy was performed, which revealed substantial purulent secretion and necrotic areas throughout the tracheal mucosa (Figure 2C1). The last bronchoscopic examination during hospitalization showed tracheal stenosis and granulation (Figure 2C2).
Pathologic results of tracheal biopsy for the three cases. (A) Case 1 exhibited neutrophil infiltration and fibrinoid necrosis. (B) Case 2, it showed fibrinoid necrosis and purulent cells. (C) Case 3 demonstrated fibrinoid exudation and substantial Aspergillus load. (Hematoxylin and eosin staining, 200 x magnification).
fped-08-00360-g0003.jpg
PMC7363969_03_fped-08-00360-g0003.jpg
F3
Histologic evaluation showed inflammatory necrotic tissue and Aspergillus fumigatus infection (Figure 3C).
Imaging findings of the three cases. (A) Case 1 showed membranous material that was strongly adherent to the tracheal wall. (B) Case 2 showed inflammation in bilateral lungs. (C) Case 3 had local stenosis of right main bronchus.
fped-08-00360-g0004.jpg
PMC7363969_03_fped-08-00360-g0004.jpg
F4
Repeat CT showed local stenosis of right main bronchus (Figure 4C) and a cavity formed near the pleura in the right lower lung.