PMC5635466_01
Diffuse lymphoid infiltrates consisting of predominantly large atypical cells with plasmacytic differentiation ((a), H&E, 400x). Immunohistochemistry stains revealed that the tumor is positive for CD138 (d) but negative for CD3 (b) and CD20 (c).
CRIHEM2017-9561013.001.jpg
PMC5635466_01_CRIHEM2017-9561013.001.jpg
fig1
Biopsy revealed large CD20-negative atypical cells with brisk mitotic activity with some cells appearing plasmacytoid (Figure 1).