PMC2778822_01
Bone marrow trephine core biopsy shows a single paratrabecular lymphoid aggregate, characteristic of bone marrow involvement by follicular lymphoma (hematoxylin and eosin stain, 20x).
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fig1
The core biopsy revealed a normocellular marrow for age with a single, paratrabecular lymphoid aggregate (Figure 1), demonstrating similar immunohistochemical staining pattern to that of the right hilar mass.
Left conjunctival biopsy with diffuse lymphocytic infiltrate (hematoxylin and eosin stain, 20x).
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The biopsy showed an intact epithelium, prominent lymphatic channels with increased stromal lymphocytes (Figure 2).
The vast majority of the lymphoid cells in the left conjunctival biopsy are CD3-positive T lymphocytes (immunoperoxidase staining, 40x).
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fig3
T-cell marker (Figure 3), with only rare cells reactive for CD79a, a B-cell marker (Figure 4). The CD20 stain was negative (Figure 5). 
Rare B lymphocytes are positive for CD79a (left conjunctiva, immunoperoxidase staining, 40x).
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T-cell marker (Figure 3), with only rare cells reactive for CD79a, a B-cell marker (Figure 4). The CD20 stain was negative (Figure 5). 
The lymphocytes are negative for CD20 (left conjunctiva, immunoperoxidase staining, 40x).
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fig5
T-cell marker (Figure 3), with only rare cells reactive for CD79a, a B-cell marker (Figure 4). The CD20 stain was negative (Figure 5). 