PMC7160695_01
Radiological evaluation of CG preoperatively. A none-contrast CT scan showed a slightly hyper-dense mass located at suprasellar and the third ventricle (a). The tumor was slightly hypo-intense on Coronal and Sagittal T1WI (b,c) and slightly hyper-intense on Coronal T2WI (d). Post-contrast (gadolinium-enhanced) Coronal and Axial MRI (e,f) show prominent homogeneous enhancement.
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Brain non-contrast computed tomography showed a well-circumscribed, irregularly ovoid tumor in the third ventricle, which was slightly hyperdense (Figure 1a). The tumor demonstrated intermediate signal intensity on T1-weighted images (Figures 1b,c) and slightly high and high signal intensity on T2-weighted images (Figure 1d). Post-contrast enhancement images indicated prominent homogeneous enhancement (Figures 1e,f).
Histological and immunohistochemical features of CG. (a) Clusters and cords of epithelioid tumor cells are surrounded by variable mucinous stroma. A small number of normal epithelial cells are at the edge of the pathological section. There is a disorganized boundary between them. (b) Neoplastic cells disposed of in cords lying in a myxoid matrix with scattered lymphocytes and plasmocytes. (c) Epithelioid elements immersed in abundant lymphocytes and plasmocytes stroma. (d) The immunostained slide showed tumor cells were positive for GFAP. (e,f) Furthermore, tumor cells were diffusely positive for TTF-1. (Original magnifications: (a) 100x; (b-d) 400x; (e) 50x; (f) 400x).
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TSH, and GH (Figure 2). The Ki-67 proliferation index was low (5%), and the tumor had low-grade features consistent with CG.
Radiological evaluation of CG postoperatively. Post-contrast MRI images of the residual tumor 1 month (a,b). The size of the residual tumor decreased following GKRS (c-f).
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However, MRI 1 month postoperatively showed residual tumor under the third ventricle measuring 1.07 x 0.81 x 0.78 cm (Figures 3a,b). The size of the residual tumor decreased following radiosurgery (Figures 3c-f).