PMC4531653_01
A computed tomographic scan of the neck shows a soft tissue mass in oropharynx.
kjim-17-1-69-13f1.jpg
PMC4531653_01_kjim-17-1-69-13f1.jpg
f1-kjim-17-1-69-13
A computed tomographic (CT) scan of the neck showed a soft tissue mass in both oropharynx, soft palate and posterior laryngeal wall, and multiple lymph node enlargements of both cervical areas (Figure 1).
Light microscopic examination shows an atypical small irregular shaped lymphoid cell infiltration admixed with plasma cells, neutrophils and eosinophils (H & E, x100). Immunohistochemical staining shows a positivity for CD56 and typical angiocentricity (inlet, x100).
kjim-17-1-69-13f2.jpg
PMC4531653_01_kjim-17-1-69-13f2.jpg
f2-kjim-17-1-69-13
On immunophenotyping study, CD56 and cytoplasmic CD3 were positive and CD20 was negative (Figure 2).
Light microscopic findings of the hard palate mass show moderately differentiated squamous cell carcinoma (H & E, x100) and p53 immunoreactivity (inlet, x100).
kjim-17-1-69-13f3.jpg
PMC4531653_01_kjim-17-1-69-13f3.jpg
f3-kjim-17-1-69-13
Unexpectedly, the biopsy revealed a moderately differentiated squamous cell carcinoma with a p53 immunoreactivity (Figure 3).