PMC4835882_01
Biopsy of the patient's skin lesions. Haematoxylin and eosin stain reveals subepidermal bulla as well as fibrin net, numerous eosinophils, perivascular mixed infiltrate, and well-preserved dermal papillae within the bulla cavity
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Fig1
The diagnosis of BP was made by a skin biopsy and clinical and pathological correlation [Fig. 1].
Cutaneous melanoma lesion with surrounding vitiligo
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Fig2
Imaging after 10 weeks of treatment showed essentially stable disease, and a cutaneous metastasis on his wrist flattened and regressed [Fig. 2].
Clinical picture of ruptured bullae, erosions, and crusts of mild bullous pemphigoid exacerbation on low-dose corticosteroid treatment
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Fig3
Over the next three months, the patient's BP lesions had resolved and prednisone was tapered off, allowing for a fifth cycle of pembrolizumab [Fig. 3].