PMC8019906_01
A contrast-enhanced abdominal CT scan showing a quite large heterogenous mass with focal calcifications (A) ~9 cm in size. The lesion had not only arterial (B) but also venous enhancement, while some areas remained nonenhanced, possibly necrotic (C).
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F1
A contrast-enhanced abdominal CT scan showed a quite large heterogenous mass (diameter 9 x 8.5 cm) with focal calcifications (Figure 1).
An abdominal MRI scan was performed, and it showed the right adrenal gland lesion. It also showed a clear distinction between the lesion and adjacent structures, without any infiltration to the inferior vena cava, or presence of pathological lymph nodes, nor were there any pathological lesions or enhancement in the liver. A sagittal T2 view (a), a coronal T2 view (b), and a transverse T1 view (c).
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F2
An abdominal MRI scan was performed, and it showed the right adrenal gland lesion, with a mean signal intensity in the T1W images, and a mean signal (with a few high-intensity elements) in the T2W images (Figure 2).
The histological examination of the tumor revealed a borderline adrenocortical oncocytoma. Macroscopically, the tumor was a descriptive almost circular lesion, surrounded by a fibrous capsule. Its size was 9.4 x 8.5 x 7.3 cm, and it weighted 113 g. Microscopically, there were large round eosinophilic cells (oncocytes) with dense granular cytoplasm; nuclei were round and regular with even chromatin; small but conspicuous nucleoli were present (a, H&EX40). Immunohistochemical tests revealed that the tumor cells were positive for vimentin (b, x40), CD56, Melan A, S-100, and synaptophysin. Oncocytoma-compact nested architecture, uniform round nuclei, and abundant pink cytoplasm (c, H&E x40).
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F3
Finally, immunohistochemical tests revealed that the tumor cells were positive for vimentin, CD56, Melan A, S-100, and synaptophysin (Figure 3).