PMC7677118_01
Bronchoscopic images showing A-B; the tumor in the left main bronchus, C; the left main bronchus three weeks after biopsy of the mass and D; the left main bronchus after laser coagulation, showing white scar tissue.
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In order to evaluate the inspiratory wheeze a bronchoscopy was performed which showed a well-circumscribed hypervasculated mass on the lateral wall of the left main bronchus with subtotal occlusion of the left main bronchus (Fig. 1A and B). This was further confirmed by a second bronchoscopy performed three weeks later showing a relatively small residual tumor (Fig. 1C). The end result observed after 3 months was a small area of pale-scarred mucosa (Fig. 1D), which will be followed-up by means of 6-monthly bronchoscopy.
Computed Tomography A; transversal and B; coronal images of the chest after initial bronchoscopy showing a remaining lesion in the left main bronchus (arrow).
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Immunohistochemistry. Image showing A; HE-coloring of lesion rich in spindle cells, B; spindle-cells strongly positive for ALK.
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Meanwhile the immunohistochemistry (Fig. 3) of the dislocated tumor showed an atypical spindle-shaped cell proliferation with mitotic activity and was positive for EML4 (echinoderm microtubule associated protein-like 4) and ALK.