PMC5173513_01
A cutaneous lesion of the left mandible. A: Three months prior to admission. There was an erythematous nodule beneath the lower lip. B: On admission, there was an erythematous multilocular lesion with ulcer that measured 5x3 cm in size on his left mandible.
1349-7235-55-3383-g001.jpg
PMC5173513_01_1349-7235-55-3383-g001.jpg
g001
There was an erythematous multilocular lesion with ulceration that measured 5x3 cm on his left mandible (Fig. 1).
Light microscopy findings of a skin biopsy specimen from the left mandible. A: The biopsy specimen revealed diffuse inflammatory infiltration [magnificationx100, Hematoxylin and Eosin (H&E) staining]. B: Many yeast cells with a thick capsule (magnificationx200, H&E staining). C: Numerous periodic acid-Schiff (PAS) -positive encapsulated yeast cells (magnificationx200, PAS). D: Grocott staining of the biopsy specimen showed numerous yeast cells that were black in color (magnificationx200, Grocott).
1349-7235-55-3383-g002.jpg
PMC5173513_01_1349-7235-55-3383-g002.jpg
g002
However, many yeast-like organisms with thick capsules were observed in the skin specimens and periodic acid-Schiff and Grocott staining were positive for these organisms (Fig. 2).