PMC184447_01
Clinical photograph showing right axillary fullness and skin nodule
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F1
Examination of axilla revealed a tiny, indurated, non tender, pink skin nodule of about 5 mm diameter (figure 1) with multiple, firm, non tender, discrete, axillary lymph nodes measuring 1 to 4 cm.
Photomicrograph of sweat gland carcinoma (Hematoxyllin and eosin x 10) Figure 2A: Showing glandular pattern with dermal invasion ((Hematoxyllin and eosin x 10) Figure 2B: Diastase sensitive, PAS positive tumor cells (PAS x 10)
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F2
Excision biopsy of the lymph node and suspected primary skin lesion was performed which revealed metastatic sweat gland adenocarcinoma with solid and glandular pattern (figure 2).
PMC184447_02
Clinical photograph showing recurrent sweat gland adenocarcinoma on the arm.
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F3
A 20-year-old man presented with a 10 x 8 cm recurrent exophytic growth on the ventral lower aspect of the right arm partly overlying ante cubital fossa (Figure 3).
Photomicrograph showing the tumor cells loosely infiltrating the stroma (Hematoxylin and eosin x 10)
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F4
PAS positive and diastase resistant confirming the diagnosis of sweat gland adenocarcinoma of the apocrine origin, resected margins were free and the lymph nodes were involved (figure 4, &5). Patient was asymptomatic for two months following which he developed local recurrence and was taken up for re-excision.
Photomicrograph showing lymph node metastases (Hematoxyllin and eosin x 10)
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F5
PAS positive and diastase resistant confirming the diagnosis of sweat gland adenocarcinoma of the apocrine origin, resected margins were free and the lymph nodes were involved (figure 4, &5). Patient was asymptomatic for two months following which he developed local recurrence and was taken up for re-excision.