PMC5675842_01
(A-C) T2-weighted axial magnetic resonance imaging showed lesions in bilateral periventricular and infratentorial areas of the CNS. (D) T1-weighted contrast-enhanced image showed a simultaneous presence of asymptomatic gadolinium-enhancing lesion at the juxtacortical area of the anterior part of the insular cortex.
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F1
T2-weighted images without gadolinium enhancement (Figure 1). The serum autoantibody test was negative, and connective tissue diseases were ruled out.
PMC5675842_02
(A-C) T2-weighted axial magnetic resonance imaging (MRI) revealed multiple, ovoid-shaped, hyperintense lesions in the bilateral periventricular regions, the juxtacortical area of the left inferior temporal lobe, and the pons. (D,E) T2-weighted axial MRI showed new lesions in the periventricular regions and the cerebellum. (F) T1-weighted contrast-enhanced image showed one asymptomatic gadolinium-enhancing lesion in the right frontal lobe.
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F2
T2-hyperintense lesions in characteristic locations (Figure 2): periventricular, juxtacortical, and infratentorial regions, as well as one gadolinium-enhancing lesion on the frontal lobe. MS was suspected, and lumbar puncture was done. The CSF total leukocyte count and protein level were normal but isoelectric focusing revealed OCBs different from bands in serum.