PMC2597752_01
Transesophageal echocardiography showing a floating mass in the left atrium.
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Transesophageal echocardiography (TEE) revealed a 1.5 cm floating mass that originated from the roof of the left atrium, near the mouth of right upper pulmonary vein (Figure 1), strongly suggestive of a floating thrombus.
Microscopic analysis of a specimen from the atrial mass disclosed highly polymorphic tumor cells and vascular channels (arrow) with erythrocytes (H&E, Original magnification x 200).
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Focally, the tumor showed little vascular channels with some erythrocytes within the lumina (Figure 2a). CD31, CD34, as well as vimentin (Figure 2b). Cytokeratins, desmin and smooth muscle actin were negative. Reaction with MIB-1 revealed a high proliferation rate, with up to 30% of tumor cells positive for MIB-1 (Figure 2c).