PMC4775785_01
Slit lamp images of the right eye. (a) Erythematous flesh-like tumor affecting most of the conjunctiva, which is more prominent in the inferior location. (b) After treatment, there was significant lesion regression. Note the scar at the biopsy site (arrow).
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Slit lamp examination of the right eye showed rubbery erythematous growth of the conjunctiva extending circumferentially around the globe; however, it was more prominent in the inferior part of the conjunctiva (Figures 1(a) and 1(b)).
Histopathological analysis of the biopsy. (a) The conjunctiva was extensively infiltrated by atypical lymphocytes with epidermotropism (arrowhead; Hematoxylin and Eosin [H and E], 200x). (b) At higher magnification, the tumor showed atypical small to medium sized lymphocytes with irregular nuclei and clumped chromatin (arrow). Macrophages and reactive lymphocytes were also seen (H and E, 400x). (c) The neoplastic cells were positive for CD3 (200x). (d) Decreased coexpression by the neoplastic lymphocytes was noticed (100x). (e) CD20 was only expressed by the scattered reactive B-cells (100x). (f) Proliferative index estimated by nuclear positivity for KI-67 antigen was approximately 20% (400x).
CRIOPM2016-4786498.002.jpg
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