PMC2586161_01
Leiomyosarcoma composed of a dominant population of neoplastic spindle cells: (a) intermingled with giant neoplastic cells and multifocal necrosis (b).
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fig1
Patient underwent transurethral resection of the prostate (TURP), and pathology revealed a dominant population of neoplastic spindle cells intermingled with giant neoplastic cells and multifocal necrosis that involved almost the entire tumor (Figures 1(a), 1(b)).
Immunohistochemistry demonstrates that tumor cells express smooth muscle actin (a) and vimentin (b).
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fig2
Specifically, tumor cells expressed smooth muscle actin (Figure 2(a)), vimentin (Figure 2(b)), and CD44, while they exhibited no staining for S-100, cytokeratins, and CD117 (c-KIT).