PMC5301098_01
Fundus photograph of the left eye showing myopic disc and posterior staphyloma. The superior border of the staphyloma was located far from the macula (a). Fluorescein angiogram showing a belt-shaped area of granular hyperfluorescence corresponding to the superior border of the posterior staphyloma (b). Indocyanine green angiogram showing hypofluorescence due to choriocapillaris occlusion at the superior border of the staphyloma (c).
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F1
Fundus examination showed posterior staphyloma in both eyes, the border of which was located superior and temporal to the macula (Fig. 1a) in both eyes. Fundus fluorescein angiography showed a belt-shaped area of granular hyperfluorescence corresponding to the border of the staphyloma in both eyes (Fig. 1b). The hypofluorescence was more pronounced in the early phase of indocyanine green angiography (Fig. 1c).
Before bevacizumab treatment in the left eye, horizontal cross-sectional optical coherence tomography images revealed submacular fluid (a), and a cross-sectional optical coherence tomography image of both the macula and the superior border of the posterior staphyloma revealed the consecutive presence of subretinal fluid spreading from the superior border of the posterior staphyloma to the macula (b).
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F2
Optical coherence tomography demonstrated that subretinal fluid (SRF) was located on the superior border of the staphyloma in both eyes; submacular fluid had spread to the macula in only the left eye without choroidal neovascularization or polypoidal lesions (Fig. 2).
After a single intravitreal bevacizumab injection, the serous macular detachment was improved (a). After 4 consecutive monthly intravitreal bevacizumab injections, the serous macular detachment resolved (b), and SRF became localized to the superior border of the staphyloma and persisted for 12 months.
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F3
At 4 months after the treatment, the SRF dissipated from the macula and became localized at the border of the staphyloma, and metamorphopsia had disappeared (Fig. 3).