PMC8655809_01
Computed tomography abdomen and pelvis showing the pancreatic and ovarian masses. (A) Mass lesion (5.9 x 3.6 cm) replacing the distal body and tail of the pancreas (arrows) with encasement of the adjacent vascular structures. The mass is inseparable from the posterior wall of the stomach and the left adrenal gland. (B) Cystic mass (6.9 x 5.6 cm) in the left adnexal region (arrows).
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Follow-up imaging revealed a minimal decrease in size of the invasive mass within the pancreatic body and tail to 5.9 cm (Fig. 1A). The pelvic mass, however, appeared to have enlarged, with extension into the abdomen, in keeping with malignancy (Fig. 1B).
Histologic sections of the pancreatic and ovarian masses. (A) Permanent sections of the pancreatic mass showed a few residual viable groups of poorly differentiated adenocarcinoma, with evidence of extensive treatment effect (10 x objective). (B) Sections of the enlarged left ovary showed multiple neoplastic cysts, which were lined by intestinal type epithelial cells that showed stratification (10 x objective).
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Permanent sections (Fig. 2A) showed only a few residual viable groups of poorly differentiated adenocarcinoma, morphologically consistent with pancreatic ductal carcinoma (1.0 cm in greatest dimension). Microscopic sections of the enlarged left ovary (Fig. 2B) showed multiple neoplastic cysts lined by intestinal type epithelial cells that showed stratification, including foci of cribriform architecture.