PMC9793728_01
Clinical feature. The lesion on the right ear.
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Histological features. (A) Aspergillus clusters can be seen (red arrow), primarily neutrophil (black arrow)-dominated inflammatory necrotic tissue and keratinized epithelium (HE x100). (B) PAS-positive hyphae of aspergillus (PAS x400). (C) Fungi are Alcian blue positive (AB x400). (D) Basal cell-like tumor masses can be seen in the dermis, with extensive infiltration between fibers, fenestrated arrangement of cells around the masses (red arrow) (HE x200).
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Histopathological examination of the lesions showed visible Aspergillus clusters, mostly neutrophil-dominated inflammatory necrotic tissue and keratinized epithelium (Figure 2A). Acid-Schiff stain showed fungal hyphae, which were septate and branched (Figure 2B). Alcian blue staining shows fungal mycelium and spores (Figure 2C). A second histopathological examination showed a basal cell-like tumor mass in the dermis with extensive infiltration between the fibers and a fenestrated arrangement of cells around the mass (Figure 2D).