PMC9529523_01
(a) Electron microscopic image of endomyocardial biopsy, 12k magnification, demonstrating elongated enlarged mitochondria (orange arrow), myelin figure (green arrow), and curvilinear body (red arrow). (b) Electron microscopic image of endomyocardial biopsy, 20k magnification, demonstrating myelin figure (yellow arrow).
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PMC9529523_01_CRIRH2022-6503453.001.jpg
fig1
Endomyocardial biopsy showed no features of myocarditis but demonstrated occasional curvilinear bodies with myelin figures and enlarged mitochondria (Figures 1(a) and 1(b)) consistent with hydroxychloroquine-induced cardiomyopathy on electron microscopy.