PMC3934613_01
Clinical appearance at initial presentation. Grouped vesicular lesions are visible on the vulva, showing a typical 'frog spawn' appearance.
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F1
A 16-year-old Japanese girl presented with a 9-year history of vesicles on both sides of the vulva (fig. 1).
Histopathologic analysis reveals multiple thin-walled, dilated lymphatic spaces within the papillary dermis. Hematoxylin and eosin staining at low magnification.
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F2
Histopathologic examination revealed multiple thin-walled, dilated lymphatic spaces that contained lymphocytes and erythrocytes in the papillary dermis (fig. 2).
Clinical appearance after final laser treatments. No recurrence has occurred after 2 years, but follow-up is continuing.
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F3
No recurrence has been detected yet, 2 years after the last treatment, although follow-up is continuing (fig. 3).