PMC8060096_01
(a, b) The classic neurofibromas of neurofibromatosis type 1 covering the entire surface of the upper extremities and trunk.
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In addition, he had multiple, small-sized, flesh-colored, dome-shaped fibromas clustered on the trunk, abdomen, and upper extremities (Figure 1).
CT of the abdomen, axial view, showing a soft tissue mass anterior to the abdominal aorta and posterior to the body of the pancreas measuring 8 x 6 x 4 cm (red arrow) representing lymphadenopathy from the diffuse B cell lymphoma.
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A computed tomography (CT) scan of the abdomen showed a dominant, oval-shaped, soft tissue density in the middle of the upper abdomen, superficial to the abdominal aorta and multiple paraesophageal lymphadenopathy, the largest measuring 8 x 4 x 6 cm (Figure 2).
The soft tissue biopsy under H&E stain and high power: no atypia or malignancy noted.
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B cell lymphoma (DLBCL) (Figures 3 and 4). Bone marrow aspirates did not show atypical cells.
Immunohistochemical stains show that the majority of cells in the specimen are CD20-positive B cells. There is background smaller CD3-positive T-cells. Overall, the findings are most consistent with a diffuse large B cell lymphoma.
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B cell lymphoma (DLBCL) (Figures 3 and 4). Bone marrow aspirates did not show atypical cells.