PMC6601469_01
Optical coherence tomography showing (a) full thickness macular hole, (b) first closure of macular hole with residual subretinal fluid, (c) reopening of macular hole, and (d) second closure of the macular hole.
CRIOPM2019-2398342.001.jpg
PMC6601469_01_CRIOPM2019-2398342.001.jpg
fig1
CME had resolved with improved BCVA (20/30 OU) after 6 months of therapy. 9 months later, foveal thinning developed which progressed to a FTMH one month later (Figure 1(a)), reducing BCVA to 20/60 OS. OCT showed a closed MH, with residual subretinal fluid (SRF) (Figure 1(b)). OCT showed reopening of the MH (Figure 1(c)). The patient scheduled MHS but wanted to wait for 3 months, hoping for spontaneous resolution. 3 months later, MH spontaneously closed (Figure 1(d)) with improved VA to 20/80 OS.
PMC6601469_02
Optical coherence tomography showing (a) tiny full thickness macular hole, (b) first closure of macular hole, (c) reopening of macular hole, and (d) reclosure of macular hole.
CRIOPM2019-2398342.002.jpg
PMC6601469_03_CRIOPM2019-2398342.002.jpg
fig2
OD (20/60). OCT showed MH (Figure 3(a)). 1 month later, spontaneous closure of the MH was observed (Figure 2(b)) with BCVA of 20/50.
PMC6601469_03
Optical coherence tomography showing (a) tiny full thickness macular hole, (b) first closure of macular hole, (c) reopening of macular hole, and (d) reclosure of macular hole.
CRIOPM2019-2398342.002.jpg
PMC6601469_03_CRIOPM2019-2398342.002.jpg
fig2
OD (20/60). OCT showed MH (Figure 3(a)). 1 month later, spontaneous closure of the MH was observed (Figure 2(b)) with BCVA of 20/50.
Optical coherence tomography showing (a) full thickness macular hole, (b) first closure of the macular hole, (c) reopening of the macular hole, and (d) second closure of macular hole.
CRIOPM2019-2398342.003.jpg
PMC6601469_03_CRIOPM2019-2398342.003.jpg
fig3
OD (20/60). OCT showed MH (Figure 3(a)). 1 month later, spontaneous closure of the MH was observed (Figure 2(b)) with BCVA of 20/50. MH with intraretinal cystic spaces (Figure 3(c)). MHS was recommended but the patient declined. 1 month later, the MH had again spontaneously closed with a few cystic spaces and minimal SRF which resolved gradually (Figure 3(d)) although the BCVA was 20/125.