PMC3715979_01
PMC3715979_02
Chest X-ray showing mass lesion in the right mid-zone (Case 2)
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F1
She was found to have mass lesion in the apical segment of right lower lobe by chest X-ray [Figure 1] and CT scan [Figure 2].
CT scan chest showing mass lesion in the apical segment of right lower lobe (Case 2)
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F2
She was found to have mass lesion in the apical segment of right lower lobe by chest X-ray [Figure 1] and CT scan [Figure 2].
PMC3715979_03
H and E (original magnification x100) showing lung alveoli on top, bronchiole and embryonal rhabdomyosarcoma below
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F3
H and E (original magnification x400) showing spindle-shaped cells, with a mitotic figure in the center. Few strap cells with bright eosinophilic cytoplasm (arrow)
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F4
Immunohistochemical (ABC technique, x400) examination shows cytoplasmic positivity for desmin in the spindle cells
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F5
Immunohistochemical (ABC technique, x100) examination shows positivity for MyoD 1 in the nuclei of spindle cells
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F6
MyoD 1 [Figure 6] and H-caldesmon, suggestive of embryonal RMS of anaplastic type. Metastatic workup was negative.