PMC3130920_01
Patient 1 (Tables 2 and 3) with neuroretinitis: optic disc edema and macular star (A) and AION (B) with characteristic visual fields defect and positive serology for Bartonella henselae and history of cat scratch.. Abbreviation: AION, anterior ischemic optic neuropathy.
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In his left eye, neuroretinitis was observed 1 month after cat scratching (Figure 1A). This patient developed anterior ischemic optic neuropathy (AION) 3 weeks after the onset of disease (neuroretinitis) with characteristic visual field defect and had a poor outcome in spite of treatment (Figure 1B); in addition, tubulointerstitial nephritis occurred 3 months after the diagnosis of neuroretinitis suggesting possible tubulointerstitial nephritisuveitis (TINU) syndrome.
PMC3130920_02
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PMC3130920_04
Patient 4 (Tables 2 and 3). A, B, C, D: BRVO along with cystoid macular edema (CME) in OCT and signs of vasculitis (FA arrows) treated previously with laser and intravitreal bevacizumab (positive serology for Bartonella henselae and history of cat scratch). E, F, G, H: After 4 weeks' treatment with azithromycin and rifampicin, there is a significant improvement of fundus findings along with FA findings and total regression of CME (OCT).. Abbreviations: BRVO, branch retinal vein occlusion; FA, fluorescein angiography; OCT, optical coherence tomography; CME, cystoid macular edema.
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Thirty-six-year-old male with BRVO in his left eye and recurrence of macular edema after the treatment with laser photocoagulation and intravitreal bevacizumab (Figure 2A, B, C, D). In addition, pedantic analysis of fluorescein angiography features took into account along with the BRVO the presence of retinal phlebitis (Figure 2C and D). He was treated with rifampicin 600 mg daily and azithromycin 500 mg daily for 4 weeks, resulting in an improvement of visual acuity and regression of macular edema (Figure 2E, F, G, H).
PMC3130920_05
Patient 5 (Tables 2 and 3) with positive serology for Bartonella henselae and history of cat scratch, presenting with unilateral intermediate uveitis. A) before treatment and B) after 4 weeks treatment with ciprofloxacin: regression of uveitis (the absence of snowballs is notable).
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At the site of inoculation a pustule was formed and after 6 weeks intermediate uveitis was observed in his left eye (Figure 3A). He was treated with ciprofloxacin 500 mg 12-hourly for 4 weeks with complete resolution of the intermediate uveitis (Figure 3B).
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PMC3130920_08
Patient with bilateral intermediate uveitis and peripheral vasculitis (increased IgG titers against B. quintana; patient 8 in Tables 2 and 3). (A) and (B) right eye with snowballs masking the vessels with mild vasculitis in fluorescein angiography (FA), (C) and (D) the vasculitis is more prominent in left eye; in FA segmental periphlebitis is present.
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Bilateral intermediate uveitis along with peripheral vasculitis was observed (Figure 4A, B, C, D).
PMC3130920_09
Recurrent nongranulomatous iridocyclitis with posterior synechiae in the left eye of a patient working in a furs elaboration industry, with positive serology for B. quintana (patient 9 in Tables 2 and 3).
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The iridocyclitis was a nongranulomatous one with posterior synechiae (Figure 5).
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