PMC10299828_01
The brain computed tomography of the patient. (A-G) Represented contrast-enhanced computed tomography (CT) images performed 4 h after admission showed mild cortical swelling of bilateral ventral temporal lobes that slightly pushed into tentorial incisura. In contrast, the gray-white matter differentiation was preserved in fronto-pareital lobes. (H-N) Represented contrast-enhanced CT images performed 16 h after admission (6 h after cardiopulmonary cerebral resuscitation) showed diffuse cerebral and cerebellar swelling and bilateral uncal herniation with the inferior displaced brainstem.
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F1
Computed tomography (CT) of the head with contrast medium (Figures 1A-G), performed 4 h after arrival, depicted bilateral mild cortical swelling, especially bilateral ventral temporal lobes, slightly pushing into tentorial incisura, indicating possible acute encephalitis. Six hours after CPCR, another head CT (Figures 1H-N) showed diffuse cerebral and cerebellar swelling and bilateral uncal herniation with the inferior displaced brainstem.
Serial biochemical data and cytokines profile in serum and cerebrospinal fluid. (A) The clinical course and the dynamic changes in inflammatory markers of this patient. (B, C). The serum cytokine profile that showed an escalating trend (B) and a falling trend (C).
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F2
The clinical course and the dynamic changes in inflammatory markers were summarized in Figure 2A. Table 1, showed an increase in multiple cytokines including GM-CSF, IL-1beta, IL-10, IL-12p70, MIP-1alpha, IL-2Ralpha, IL-1Ralpha, IL-6, IL-8, and MCP-1 from both serum and CSF, with a more prominent rise in the CSF than in the serum. The trend of the cytokines over time is presented in Figures 2B, C.