PMC3938370_01
PMC3938370_02
Blackened plaque around the surgical ulcer in the third interdigital space of the
right foot
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PMC3938370_02_abd-89-01-0157-g01.jpg
f01
At dermatological examination in our service, she presented a blackened plaque around the surgical ulceration (location of biopsy) in the third interdigital space of the right foot (Figures 1 and 2) and a painful palpable hardened mass on the root of right thigh measuring approximately 8 cm.
Another angle of the lesion in the third interdigital space of the right foot, which
gives a better view of the blackened area
abd-89-01-0157-g02.jpg
PMC3938370_02_abd-89-01-0157-g02.jpg
f02
At dermatological examination in our service, she presented a blackened plaque around the surgical ulceration (location of biopsy) in the third interdigital space of the right foot (Figures 1 and 2) and a painful palpable hardened mass on the root of right thigh measuring approximately 8 cm.
Dermoscopy showing the destructured melanocytic lesion, irregular multifocal
pigmentation with areas of light brown, dark brown, black, and grey, brown spots and
globules with irregular distribution and an amorphous grey-blue area. The centre
presents as an area of secondary scar tissue from a previous biopsy
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f03
The centre presented a secondary scar area from a previous biopsy (Figure 3).
Histology: superficial disseminative melanoma with a nodular component, noting in the
epidermis adjacent to the nodule (to the right) epidermotropism until the granulosa
layer. (HE 40x)
abd-89-01-0157-g04.jpg
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f04
Review of the slide confirmed diagnosis of superficial spreading melanoma with a nodular component, Breslow index 6.3mm, Clark level IV, presence of ulceration with 5.5 mm extension, 13 mitoses in 10 high power fields, angiolymphatic invasion, absence of regression, and vertical growth phase (Figures 4 and 5).
Histology: at higher magnification, note the intense nuclear atypia and mitotic
figures. (HE 400x)
abd-89-01-0157-g05.jpg
PMC3938370_02_abd-89-01-0157-g05.jpg
f05
Review of the slide confirmed diagnosis of superficial spreading melanoma with a nodular component, Breslow index 6.3mm, Clark level IV, presence of ulceration with 5.5 mm extension, 13 mitoses in 10 high power fields, angiolymphatic invasion, absence of regression, and vertical growth phase (Figures 4 and 5).