PMC6637455_01
Color fundus photograph of the right eye (1a) showing multiple yellowish flecks over the posterior pole with a pale yellow confluent lesion with irregular borders nasal to the fovea with a speck of hemorrhage over it suggestive of CNVM; left eye (1b) showing multiple yellow flecks over the posterior pole.
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F1
On fundus examination, the right eye showed multiple yellowish flecks over the posterior pole and a pale yellow confluent lesion with irregular borders nasal to the fovea with a speck of hemorrhage over it, while the left eye showed multiple yellow flecks over the posterior pole (Figure 1 (Fig. 1)).
Blue autofluorescence image of the right eye (2a) showing multiple hyperautofluorescent lesions corresponding to flecks and a hypoautofluorescent lesion corresponding to the CNVM in color fundus; left eye (2b) showing multiple hyperautofluorescent lesions corresponding to flecks.
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F2
Blue autofluorescence image of both eyes showed multiple hyperautofluorescent lesions corresponding to flecks and the right eye showed a hypoautofluorescent lesion corresponding to the CNVM (Figure 2 (Fig. 2)).
Fundus fluorescence angiography of the right eye (3a) showing an area of increasing hyperfluorescence in late phase suggestive of classical CNVM leakage with small areas of hyperfluorescence staining corresponding to flecks; left eye (3b) showing small areas of hyperfluorescence staining corresponding to flecks.
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F3
Fundus fluorescein angiography (FFA) of the right eye (Figure 3a (Fig. 3)) showed an area of increasing hyperfluorescence in late phase suggestive of classic CNVM with small areas of hyperfluorescent staining corresponding to flecks; the left eye (Figure 3b (Fig. 3)) showed small areas of hyperfluorescence staining corresponding to flecks.
SD OCT of the right eye pre treatment (4a) showing a juxtafoveal CNVM with surrounding subretinal fluid; the right eye post anti-VEGF treatment (4b) shows minimal subretinal fluid with regressing CNVM and adjacent scarring. The right eye post second anti-VEGF injection (4c) shows completely regressed subretinal fluid.
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F4
Spectral domain optical coherence tomography (SD OCT) of the right eye pre treatment (Figure 4a (Fig. 4)) showed a juxta foveal CNVM with surrounding subretinal fluid. A repeat SD OCT was done (Figure 4b (Fig. 4)) which showed minimal subretinal fluid with regressing CNVM and adjacent scarring. Ranibizumab in her right eye. Repeat OCT was done on follow-up visit after a month which showed a complete regression of the subretinal fluid and her vision was maintained (Figure 4c (Fig. 4)).