PMC5805846_01
Chest computed tomography scan. (A) Before treatment with osimertinib, the scan showed the multiple nodules in the right upper lobe of the lung. (B) Two weeks after initiation of osimertinib, the scan showed remarkable remission of the tumor. (C) Two months after initiation of osimertinib, the scan showed visible ground-glass opacities in the right lung.
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Fourteen days later, a rapid improvement in the multiple pulmonary metastases was observed (Fig. 1A and B). However, on day 55 of osimertinib treatment, follow-up chest computed tomography (CT) showed patchy ground-glass opacity (GGO) (Fig. 1C).