PMC4378700_01
Gadolinium enhanced T1 weighted MRI of the abdomen with fat saturation prior to treatment with radioembolization shows right hepatic lobe with 8 cm x 9 cm mass (06/07/2013). Enhancement within the tumor indicates tumor viability.
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A CT scan of the abdomen in July 2013 prior to the radioembolization procedure showed an 8 cm x 9 cm right lobe hepatic mass, as shown in Figure 1. MRI of the abdomen following radioembolization treatment in September showed decrease in the overall size of the dominant right lobe mass and decreased enhancement within the masses, indicative of a partial response according to modified RECIST criteria (Figures 1 -3).
Same lesion on MRI 2 months following radioembolization with yttrium 90 resin microspheres (09/20/2013). There is no enhancement within the central portion of the mass and the tumor has decreased slightly in size, consistent with partial response by mRECIST criteria.
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MRI of the abdomen following radioembolization treatment in September showed decrease in the overall size of the dominant right lobe mass and decreased enhancement within the masses, indicative of a partial response according to modified RECIST criteria (Figures 1 -3).
Angiography (08/08/2013) of right hepatic lobe lesion before Y90 treatment showing extensive tumor vascularity of the dominant right lobe lesion being fed by branches of the right hepatic artery. Coil embolization of gastroduodenal artery and right gastric artery had been previously performed to prevent nontargeted delivery of microspheres to the gastrointestinal tract.
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fig3
MRI of the abdomen following radioembolization treatment in September showed decrease in the overall size of the dominant right lobe mass and decreased enhancement within the masses, indicative of a partial response according to modified RECIST criteria (Figures 1 -3).
CEA trend from August 2013 to February 2014.
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Our patient had a good response after the procedure, as shown by CEA levels.  Figure 4 shows the decrease in CEA levels while the patient was in our service.