PMC6333068_01
Mammography with suspect opacity of the superior external quadrant of the left breast
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Eighteen days prior to hospital admission, a routine mammography showed a peripheral opacity of the superior external quadrant of the left breast (Figure 1).
Breast biopsy (HE coloration): invasive ductal carcinoma
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Biopsy showed an invasive ductal carcinoma, estrogen-receptor 27% positive, progesterone-receptor negative, HER-2 positive (Figure 2).
CT with infra-diaphragmatic lymphadenopathy
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A total-body 18 F-FDG PET-CT (Figures 3, 4) showed a hypermetabolic mass of the left breast, with multiple hypermetabolic lymphadenopathies in the axillar, internal mammary, intercostal, and para-vertebral regions.
CT with infra-diaphragamatic and retroperitoneal lymphadenopathy
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A total-body 18 F-FDG PET-CT (Figures 3, 4) showed a hypermetabolic mass of the left breast, with multiple hypermetabolic lymphadenopathies in the axillar, internal mammary, intercostal, and para-vertebral regions.
Bone marrow biopsy: CD 61 staining (showing stained megacaryocytes)
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Biopsy of left latero-aortic lymphadenopathy (HE coloration)
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