PMC7174964_01
Imaging findings: (a) brain computed tomography scan at diagnosis; (b) positron emission tomography-computed tomography findings at diagnosis; (c) pathological findings at diagnosis (hematoxylin and eosin staining) and immunostaining with anti-CD3, anti-CD4, anti-CD8, anti-CD7, and anti-CD20; (d) flow cytometry analysis at diagnosis.
CRIHEM2020-1514729.001.jpg
PMC7174964_01_CRIHEM2020-1514729.001.jpg
fig1
A 74-year-old male patient with a history of left lung inferior lobe resection due to localized lung cancer who complained of rhinostenosis was diagnosed with a tumor in the right nasal cavity (Figure 1(a)). Positron emission tomography-computed tomography (PET-CT) showed intense focal uptake of SUVmax 18.3 in the right nasal cavity (Figure 1(b)). Flow cytometry (FCM) analyses showed clear CD7 and CD19 positivity in the tumor cells, while CD20 was expressed at weak intensity (Figure 1(d)). Immunohistochemistry (IHC) results were positive for L26 (CD20), bcl-2, bcl-6, and MUM1 and negative for CD3, CD4, CD8, CD7 (LP15; Novocastra), CD10, and EBER (Figure 1(c)).