PMC6358580_01
(A) Liver biopsy revealing typical characteristics of a bile acid synthesis defect with giant cell hepatitis, marked canalicular cholestasis, and ductular reaction with fibroedematous expansion of portal areas. (B) Liver biopsy revealing typical characteristics of a bile acid synthesis defect with minute areas of confluent hepatocellular necrosis.
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F1
A percutaneous liver biopsy revealed giant cell hepatitis and minute areas of confluent hepatocellular necrosis (Figure 1).