PMC8165557_01
(A) Optic coherence tomography (OCT) of optic nerve head (OHN) shows edema of the right eye optic nerve head (OD), as thickening of retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) (given in Summary Parameters and temporal-superior-nasal-inferior-temporal (TSNIT) and on table and graphic on the right side of image). Values for the left eye (OS) are normal. (B) Four months after optic neuritis-the right eye optic disc edema is withdrawn and some atrophic changes appeared, most prominently in superior quadrant and as average thinning of RNFL (marked in yellow) and focal loss volume (FLV%) (marked in red) on the right eye (OD), compared to the left eye (OS) normal values.
IMCRJ-14-349-g0001.jpg
PMC8165557_01_IMCRJ-14-349-g0001.jpg
f0001
Examination of his right fundus was notable for partial swelling of the optic nerve head and ganglion cell layer (Figure 1A). The visual evoked potentials (3C PVEP) showed slightly prolonged latency of the p100 wave, and OCT suggested slight thinning of optic nerve fibers and ganglion cells, after optic neuritis (Figure 1B).
(A) Computed perimetry (visual field) at the end of pulse corticosteroid therapy-on the left eye (left side of figure) there is some sensitivity and pattern reduction (MD and PSD values); on the right eye (right side of figure) variables are still disturbed, but better than initial ones (described in the text): VFI 57%, mean defect (MD) is halved (-15.05 dB) and pattern deviation (PSD) is now differentiated into scotomas. (B) normalization of visual field, four months later, with residual slight reduction of sensitivity on the right eye (right side of figure).
IMCRJ-14-349-g0002.jpg
PMC8165557_01_IMCRJ-14-349-g0002.jpg
f0002
On the fifth day of therapy his visual acuity was significantly better (20/63 or 0.3), and visual field showed significant improvement (Figure 2A). At his final 3-month follow up, his visual acuity and computed visual field on the right eye were normal (VOD 20/20 or 1.0; Figure 2B).