PMC9726840_01
Non-blanchable erythematous macules and palpable purpura on patient's leg(s).
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A 71-year-old woman who had previously been diagnosed with rheumatoid arthritis presented with generalized edema, worsening hypertension, and non-blanchable erythematous papules with reticulation on both legs, which had been presented for 4 months, as shown in Figure 1.
Kidney biopsy pathology. Light microscopic examination stained with hematoxylin and eosin (a; original magnification, x400) and periodic acid-Schiff (b; original magnification, x400). Immunofluorescence study of IgM (c; original magnification, x400), kappa (d; original magnification, x400), and lambda (e; original magnification, x400).
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A percutaneous kidney biopsy was performed and kidney pathology is shown in Figures 2 and 3.
Electron microscopic examination of kidney pathology showing electron-dense deposits in the capillary loop (a; bar = 2 mum). Higher magnification of electron-dense deposits showing organized structures (b; bar = 500 nm).
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A percutaneous kidney biopsy was performed and kidney pathology is shown in Figures 2 and 3. Figure 3 displays the results of an electron microscopic (EM) study, which revealed the deposition of organized electron-dense materials at the mesangium and subendothelium.