PMC10436618_01
Bone marrow biopsy showing hemophagocytosis by histiocyte.
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Bone marrow biopsy revealed occasional hemophagocytic cells ( Figure 1 ).
The patient's clinical course in hospital. DXM, dexamethasone; MP, Methylprednisolone; PSL, prednisolone;VP-16,etoposide;CsA, Cyclosporine A;CTX, cyclophosphamide.
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SLE complicated with secondary HLH, and 5 days of pulsed intravenous methylprednisolone with a dose of 200mg daily was administered for shock treatment. Subsequently, a combination treatment of etoposide (100mgx3/week, accumulated 1000mg), cyclosporine (50mg, bid), cyclophosphamide (200mg, qw), and entecavir was administered, which successfully reversed the patient's body temperature to the normal range ( Figure 2 ).