PMC1395313_01
A) 99mTc-HMDP bone scintigraphy showing many lesions with accumulation in the left ribs, which were diagnosed as multiple costal metastases. B) After chemotherapy with S-1 and CPT-11, the costal metastases have resolved.
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F1
99mTc-HMDP bone scintigraphy revealed many lesions with accumulation in the left ribs, which were diagnosed as multiple costal metastases (Figure 1A). This therapy resulted in resolution of the multiple costal metastases (Figure 1B), and a 50% reduction of the local lesion on CT.
A) Microscopic image of tumor obtained by colonic biopsy before chemotherapy, showing well-differentiated adenocarcinoma. B) Microscopic image of surgical specimen after chemotherapy. Half of the tumor shows degeneration, necrosis, and fibrosis.
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F2
Half of the tumor was degenerative, necrotic, and fibrotic (Figure 2A and 2B).