PMC9825212_01
(a, b) Purpuric 1-3 macules located in the lower extremities extending to the anterior and medial thighs.
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fig1
Pfizer-BioNTech COVID-19 vaccine six months before evaluation that was self-limited and resolved without further intervention. Physical examination was remarkable for purpuric 1 to 3 mm macules, some barely palpable and located in the shin and anterior and medial thighs of the lower extremities (Figures 1(a) and 1(b)).
(a, b) 100x low-power image (a) and 200x medium-power image (b) showing extravasation of erythrocytes, perivascular infiltrate of neutrophils, nuclear dusts, and eosinophils, and features of leukocytoclastic vasculitis.
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fig2
A skin biopsy was performed and showed extravasation of erythrocytes, perivascular infiltrate of neutrophils, nuclear dust, and eosinophils, consistent with LCV and negative direct immunofluorescence (Figures 2(a) and 2(b)).