PMC4318039_01
(a) Irregular, circumscribed erythematous, infiltrated plaque with complete alopecia and an uneven surface studded with multiple whitish globoid structures, on the left parietal scalp of a 5-year-old boy, (b) Same plaque showing a marginal extension of milia in a linear fashion along the posterior nuchal area following blaschkoid patten
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F1
The surface of the plaque was devoid of hair and studded with multiple white milia of variable sizes [Figure 1a]. From the lower margin of the plaque, few discrete minute milia spread beyond the inferior margin of the original lesion, to be distributed in a linear fashion, extending up to the posterior nuchal area following a Blaschkoid pattern [Figure 1b].
(a) H and E, x4 scanner view showing multiple cysts lined by epithelia and filled with strands of keratin, in the dermis, interspersed between cross sections of hair follicles with sparse inflammatory infiltrates, (b) H and E, x10 view showing a cross sectional view of a keratin-filled milium adjacent to a hair follicle, which is in the process of giving rise to a milium, (c) H and E, x40 view showing a closer view of one of the milia in the dermis, lined by epithelia and the keratin strands within
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F2