PMC6874140_01
Percent change in targeted blood proteins during RAAM. A previous study determined that these proteins are not acutely upregulated following an exercise bout, potentially implicating them as strong candidates for NFOR monitoring in individuals.
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F1
Blood sample analysis indicated the largest serum protein increases during RAAM were immune-related proteins involved in complement activation and the acute phase response (Figure 1).
Intensity values for serum amyloid A4 (SAA4) before, during (morning and evening), and after RAAM competition.
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F2
A 359% increase in complement component C7 (CO7), a 231% increase in complement C4-B (CO4B), a 210% increase in serum amyloid A-4 protein (SAA4) (see Figure 2 for the time course of changes in SAA4), a 191% increase in Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4), and a 188% increase in alpha-1-antitrypsin (A1AT), occurred due to RAAM.