PMC7890130_01
Radiologic evaluation at admission. Barium enema consistent with suspicion OF HD.
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F1
Abdominal radiography showed a distal obstruction (Figure 1).
Postoperative plain X ray at the time diagnosis of eosinophilic myenteric gangliositis.
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F2
Abdominal obstruction was detected at radiography (Figure 2).
Histological features. (A) Full-thickness colon biopsy; the rectangle indicates the muscularis propria and the myenteric Plexus X4; (B) Muscularis propria with eosinophil infiltration (arrows) X60; (C) Myenteric plexus with eosinophil infiltration (arrows) between the ganglion and glial cells X40; (D) Calretinin ganglion cell positivity (arrows) X40.
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F3
Full-thickness surgical distal colon biopsies showed the presence of mature ganglion cells and revealed an eosinophilic-predominant inflammatory infiltrate in the myenteric plexus and surrounding tissues of sigmoid colon and rectum (>60 eosinophils/ 10 HPF, X40) (Figure 3).
PMC7890130_02
Histological feautures after dietary modification. Colonic mucosa with normal crypts, and rare eosinophils in the lamina propria H&E x40.
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F4