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Frontal view after explantation of the breast implants in our 62-year-old patient.
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About three months later our patient noted an erythematous area on the lateral side of the inframammary fold of the right breast (Fig. 1, Fig. 2).
Silicone residuals after explantation of the breast implants on protocol breast MRI. The diameter of the largest silicone pocket (left) is 2.3 x 1.5 cm.
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This showed bilateral subpectoral residual silicone particles, with the largest silicone pocket of about 2,3 x 1,5 cm in the left breast (Fig. 3, Fig. 4).
a) Immunohistochemistry (ALK-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. b) Immunohistochemistry (CD3-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. c) Immunohistochemistry (CD5-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. d) Immunohistochemistry (CD20-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. e) Immunohistochemistry (CD23-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient.
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B-lymphocytic infiltration (CD20+, CD5+, CD23+, ALK-) in both capsules, highly suggestive for CLL/SLL (Fig. 5a-e). Breast implant associated anaplastic large cell lymphoma (BIA-ALCL) was considered but excluded as CD30 tested negative.