PMC4943775_01
Torpedo maculopathy. a June 2010, fundus photography OS in a 15-year-old male. The magnified view shows the torpedo lesion, with the proposed origin of the pseudo-lacuna demonstrated by the arrow. b October 2015, fundus photography OS in a 15-year-old male. The magnified view shows the torpedo lesion with a markedly larger pseudo-lacuna demonstrated by the arrow.
cop-0007-0184-g01.jpg
PMC4943775_01_cop-0007-0184-g01.jpg
F1
Color fundus photography from October 2015 (fig. 1b) shows a well-defined, ovoid-shaped, hyperpigmented lesion that is 1.74 x 0.67 mm in size and temporal to the macula. Color fundus photography from June 2010 (fig. 1a) shows the same lesion 5 years ago. The appearance of a small, hypopigmented, almost pearlescent-colored spot becomes more apparent in the 2015 image (arrow in fig. 1b). The same hypopigmented spot can also be seen in the photo from 2010, although it was much smaller at that time (fig. 1a).
EDI-OCT of torpedo maculopathy taken in October 2015. a Scan at the level of the 'pseudo-lacuna' within the torpedo lesion. The white arrow corresponds to the location of pseudo-lacuna in both the infrared image on the left and the OCT image on the right. b The white arrow demonstrates a subretinal cleft through the torpedo lesion.
cop-0007-0184-g02.jpg
PMC4943775_01_cop-0007-0184-g02.jpg
F2
EDI-OCT of the lesion from 2015 demonstrates RPE clumping and migration that corresponds to the pseudo-lacuna (fig. 2a). There is also disruption of the ellipsoid zone and mild thinning of the outer retina, which is overlying a subretinal cleft (fig. 2b).
Fundus autofluorescence of OS in October 2015. The pigmented torpedo lesion is hypoautofluorescent with a rim of hyperautofluorescence. There is a small dot of hyperautofluorescence that corresponds to the pseudo-lacuna found on the color photo (white arrow).
cop-0007-0184-g03.jpg
PMC4943775_01_cop-0007-0184-g03.jpg
F3
The pseudo-lacuna lesion demonstrates an area of markedly increased autofluorescence (fig. 3).
FA of OS in October 2015. a The early-phase angiogram demonstrates a globally hypofluorescent lesion with a rim of hyperfluorescence and no neovascular activity. b The late-phase angiogram confirms no neovascular disease or leakage. The area signified by the pseudo-lacuna lesion (arrows) remains hypofluorescent.
cop-0007-0184-g04.jpg
PMC4943775_01_cop-0007-0184-g04.jpg
F4
Early and late phases of FA show a hypofluorescent lesion with a rim of hyperfluoresence (fig. 4a, b). The area of the pseudo-lacunae in the center of the lesion also remains hypofluorescent in both phases (arrow in fig. 4a, b).