PMC7516694_01
CT scan of the abdomen displaying the transmural thickening of the stomach (white blocked arrow) and the perigastric inflammation with reactive adenopathy (white arrow).
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Computed tomography (CT) of the abdomen and pelvis (Figure 1) demonstrated transmural thickening at gastric body and fundus, with associated perigastric inflammation and reactive adenopathy.
Upper endoscopy showing ulcerated lesion in the gastric fundus with the overlaying bleeding and exudative material.
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Esophagogastroduodenoscopy (EGD) revealed multiple ulcerated sessile masses in the gastric fundus with a large exudate covering mass (Figure 2).
Histological examination of lesion showing polymorphonuclear neutrophils indicating inflammation of gastric mucosa (a) and fragments of invading fungal hyphae (b).
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Biopsy of mass revealed polymorphonuclear neutrophils indicating inflammation of gastric mucosa and fragments of invasive fungal hyphae (zygomycetes) with polymerase chain reaction (PCR) and culture of the biopsy specimens detecting Rhizopus microsporus DNA (Figures 3(a) and 3(b)).
Repeat EGD showing cleared infection and ulceration in the fundus of the stomach.
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Complete resolution of gastric mucormycosis with the absence of hyphae was noted on endoscopic gastric biopsies after 16 weeks of antifungal therapy (Figure 4).