PMC9991466_01
Imaging and immunohistochemistry of the lesion. (a) CE-CT image at the first visit to our department. The soft tissue mass is visible below the right diaphragm (arrows). (b) Immunohistochemical analysis of the lesion revealed that the tumor cells were positive for calretinin (A), WT-1 (B), and D2-40 (C). (c) CE-CT image at 48 months after the start of chemotherapy. The lesions were indicative of stable disease (arrows). CE-CT: contrast-enhanced computed tomography.
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In addition, ascites and nodules were observed in the abdominal cavity (Figure 1(a)). Ber-Ep4, ER, PgR, TTF-1, claudin 4, and desmin. Based on the histopathological and immunohistochemical findings, the tumor was diagnosed as an epithelioid mesothelioma (Figure 1(b)-(A) = calretinin, (B) = WT-1, and (C) = D2-40). Because the FDG-PET findings strongly suggested peritoneal dissemination, radical treatment by surgical resection was considered difficult, and systemic chemotherapy was administered. CT performed 48 months after the start of chemotherapy showed stable disease with amelioration of the abdominal symptoms observed at the initial examination (Figure 1(c)).