PMC5376422_01
Neoplastic pleomorphic cells and physaliphorous cells, with vacuolated PAS positive cytoplasm and prominent vesicular nuclei with mild atypia, combined to small tumor cells with inconspicuous and no visible nuclei (haematoxylin and eosin, 20x and 40x).
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fig1
Neither foci of chondroid (cartilaginous) differentiation nor sarcomatous areas were observed as well (Figures 1(a)-1(c)).
Positivity of the tumor cells for EMA (20x).
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fig2
Tumor cells stained for S-100 protein (Figure 5), cytokeratin AE1/AE3 (Figure 3), EMA (Figure 2), and vimentin (Figure 4) whereas a negativity for CEA and smooth muscle actin was detected.
Positivity of the tumor cells for CKAE1/AE3 (20x).
CRIPA2017-5281239.003.jpg
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fig3
Tumor cells stained for S-100 protein (Figure 5), cytokeratin AE1/AE3 (Figure 3), EMA (Figure 2), and vimentin (Figure 4) whereas a negativity for CEA and smooth muscle actin was detected.
Positivity of the tumor cells for vimentin (40x).
CRIPA2017-5281239.004.jpg
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fig4
Tumor cells stained for S-100 protein (Figure 5), cytokeratin AE1/AE3 (Figure 3), EMA (Figure 2), and vimentin (Figure 4) whereas a negativity for CEA and smooth muscle actin was detected.
Positivity of the tumor cells for S100 (20x).
CRIPA2017-5281239.005.jpg
PMC5376422_01_CRIPA2017-5281239.005.jpg
fig5
Tumor cells stained for S-100 protein (Figure 5), cytokeratin AE1/AE3 (Figure 3), EMA (Figure 2), and vimentin (Figure 4) whereas a negativity for CEA and smooth muscle actin was detected.