PMC9106234_01
Orthopantomogram showing a well-defined multilocular radiolucency with sclerotic border in the right molar-ramus region of the mandible distal to the impacted third molar
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F1
The orthopantomogram (OPG) revealed a well-defined multilocular radiolucency with a sclerotic border in the right molar ramus region of the mandible distal to the impacted third molar [Figure 1].
A cystic lesion with epithelial lining and fibrous connective tissue capsule (H & E, x4)
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F2
The histopathologic examination of the tissue section revealed a cystic lesion with epithelial lining and fibrous connective tissue capsule [Figure 2].
The epithelium revealed uniform orthokeratinized stratified squamous epithelium with a prominent granular cell layer (a: H & E, x10). The surface showed sheaves of orthokeratin and keratin flakes were present in the cystic lumen. The basal cells were low cuboidal to flattened without nuclear palisading, hyperchromatism and reversal of polarity (b: H & E, x20). Epithelium was nonkeratinized in few areas of inflammation (c: H & E, x10)
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F3
The epithelium revealed thin, uniform orthokeratinized stratified squamous epithelium with a prominent granular cell layer with a flat basement membrane [Figure 3a]. The basal cells were low cuboidal to flattened without nuclear palisading, hyperchromatism and reversal of polarity [Figure 3b]. The epithelium was nonkeratinized in few areas of inflammation [Figure 3c].
Fibrous capsule showed dense collagen bundles, few chronic inflammatory cells, cholesterol clefts and giant cells (a: H & E, x10), hemosiderin pigments (b: H & E, x10), dystrophic calcification (c: H & E, x4) and dentinoid-like material focally (d: H & E, x4)
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F4
The fibrous capsule showed dense collagen bundles, few chronic inflammatory cells, cholesterol clefts and giant cells [Figure 4a], hemosiderin pigments [Figure 4b], dystrophic calcification [Figure 4c] and dentinoid-like material focally [Figure 4d].