PMC7308213_01
Pedigree of the family with the results of thyroid function tests. Generations are denoted by their respective roman numeral. Each subject is identified by the number just above the corresponding symbol. Laboratory thyroid function tests are aligned below each symbol. Abnormal values are in bold. Abbreviations: L-T4; levothyroxine, TT4; total thyroxine, TT3; total triiodothyronine, FT4; free thyroxine, TSH; thyroid-stimulating hormone, TBG; thyroxine binding globulin, TG; thyroglobulin, TPO Ab; anti-TPO antibody, TG Ab; anti-thyroglobulin antibody, TrT3; reverse triiodothyronine. Mia, Immulite assay done in Miami; Chi, Elecys assay done in Chicago.
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F1
TFTs demonstrated undetectable TSH on the Elecsys (<0.01) and on Immulite (<0.03) with Low FT4 (Individual II-1, Figure 1). The proband had normal neurological and psychological development on physical examination.