PMC4010014_01
Basic laboratory parameters of the patient presenting with AHF during the course of EHS. In (a), ALT and AST began to be decreased from day 3 after admission in our ICU and recovered to be normal within 2 weeks. Total bilirubin declined more slowly than transaminases. In the early stage of EHS, hypophosphatemia was evident. (b) Showed the dynamic change of Cr, LDH, CK, PT and arterial blood gas analysis with pH and PaCO2 within 2 months in our hospital. ALT, alanine aminotransferase; AST, aspartate aminotransferase; P, phosphonium; Cr, creatinine; LDH, lactate dehydrogenase; CK, creatinine kinase; PT, prothrombin time.
CRIM.CRITICAL.CARE2012-295867.001.jpg
PMC4010014_01_CRIM.CRITICAL.CARE2012-295867.001.jpg
fig1
The results of blood biochemistry exhibited very high transaminases, 2336 U/L alanine aminotransferase (ALT) (normal < 64 U/L), 1841 U/L aspartate aminotransferase (AST) (normal < 42 U/L), and significantly elevated total bilirubin 14.9 mg/dL (normal < 1.4 mg/dL) (Figure 1). Further laboratory parameters showed an evident prolongation of the prothrombin time (PT) (70.2 s, control 13 +- 3 s), D-dimer (1.22 mg/L, normal < 0.5 mg/L), an elevated lactate dehydrogenase (LDH) (1465 U/L, normal < 192 U/L), creatinine kinase (CK) (2729 U/L, normal < 269 U/L), and myoglobin (555 ng/mL, normal < 70 ng/mL) (Figure 1). The abnormal laboratory parameters returned slowly to normal within a few days while the renal function was always normal after admission (Figure 1).