PMC8650849_01
Core-genome SNP phylogeny showing the relationships between the core-genomes of isolates ECI02, ECI03 and ECI05, built using the maximum-likelihood GTR+G4 model. It demonstrates an 1120 core-genome SNP difference between ECI05 and ECI03, whilst both are more closely related to ECI02 (590 and 645 core-genome SNP differences, respectively). Notably, ECI02 and ECI05 were both blaIMP-4-positive, despite the differences in core-genome, and this is presumed to be due to its likely presence on the IncHI2 plasmid.
acmi-3-0248-g001.jpg
PMC8650849_01_acmi-3-0248-g001.jpg
F1
These were aligned to infer core SNP phylogeny (maximum-likelihood GTR+G4 model) with IQTree (see Fig. 1).