PMC9685348_01
Chest radiographs obtained at presentation showed multiple nodule shadows in both lung fields but predominantly in the right.
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Aspergillus antibody, and MAC antibody were all within normal limits. Chest radiographs obtained at presentation (Fig. 1A) showed multiple nodule shadows in both lung fields but predominantly in the right, and chest CT showed multiple nonspecific nodular shadows (Fig. 1B). Abdominal CT revealed multiple nodules scattered throughout the liver (Fig. 1C).
Chest CT showed multiple nonspecific nodular shadows.
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EHE. Eight months after the laparoscopic evaluation, follow-up CT showed both new and residual lesions in the liver, and repeat chest CT showed enlargement of the pulmonary nodules (Fig. 2).
Abdominal CT revealed multiple nodules scattered throughout the liver.
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Pathologically, lesion margins were round, square, or polyhedral, and tumors contained proliferating epithelial-like cells with abundant cytoplasm covering the vitreous interstitium (Fig. 3A). Immunohistochemistry yielded positive staining for CD31, CD34 (Fig. 3B, Fig. 3CB and C) and Factor VII, and samples were negative for AE1/AE3 signals. The Ki-67 index, which indicates the expression rate of the Ki-67 protein and thus the proliferative capacity of the tumor cells, was 4.6% (Fig. 3D).