PMC6585243_01
(a) Clinical photograph of the right ventral forearm showing white to skin-coloured flat-topped papules confined to areas of tattoo pigment. (b) Close-up of flat-topped papules with area of scale that developed after treatment with liquid nitrogen cryotherapy.
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This 36-year-old man presented with a 6-month history of skin-coloured flat-topped papules within a black coloured tattoo (Figure 1).
(a) Histopathology of biopsy specimen stained with Hematoxylin and Eosin (H&E) showing verrucae planae (200x). (b) Higher magnification of verruca plana showing koilocytes consistent with HPV infection (400x). (c) Higher magnification of tattoo dye particles within the dermis (400x).
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Histopathology revealed keratinocytes with HPV-induced changes and a diagnosis of verrucae planae was made by the pathologist (Figure 2).