PMC5302136_01
A. Brain MRI transversal T1 (top) and FLAIR (bottom) of a fifty-two-year old male patient (Case 1) with mild temporal bilateral cerebral atrophy. B. EEG telemetry of the Case 1 with Status Epilepticus (SE) before antiepileptic therapy.12 seizures were recorded during the 24-h video EEG monitoring. Technical artifacts are recorded during hand automatism. C. EEG of the same patient after antiepileptic treatment. Right fronto-central cortical dysfunction area and rhythmic slow theta activity at 6 Hz is recorded.
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A brain MRI showed bilateral mild atrophy of the temporal lobes (Supplementary Fig. 1A). This activity was correlated with hand automatisms of 20 to 40 s in duration (Fig. 1B). A second video EEG showed no seizures, but a right fronto-central cortical dysfunction and rhythmic slow theta activity at 6 Hz was found (Fig. 1C).
PMC5302136_02
A. Brain MRI transversal T1 of a sixty-two-year old female patient (Case 2) with right temporal malacic area and bilateral atrophy, predominantly frontal and temporal. B. EEG telemetry of the Case 2 with Status Epilepticus (SE) before antiepileptic therapy (periodic lateralized epileptiform discharges - PLEDs). C. EEG of the same patient after antiepileptic treatment. A second video EEG not show SE. Frontocentral and right temporal cortical dysfunction is recorded.
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A brain MRI showed a right temporal encephalomalacia and bilateral atrophy, predominantly frontal and temporal (Fig. 2A). Frequent spike-and-slow waves were present spikes-slow waves in the right posterior-temporal region were recorded (Fig. 2B). Video-EEG demonstrated right mid- to posterior-temporal theta-delta slowing and right temporal sharp waves persisting (Fig. 2C).