PMC5939145_01
Case n.1 histological examination of gastric biopsies. At morphological analysis, fundic mucosa showed severe chronic gastritis, characterized by complete atrophy of the oxyntic glands and intestinal metaplasia, and lymphoplasmacytic predominant inflammatory infiltrate (A, H&E stain, 10x). Imunohistochemical staining for chromogranin A of the same biopsy demonstrated linear and micronodular hyperplasia of the ECL cells (B, chromogranin A stain, 20x).
fped-06-00123-g0001.jpg
PMC5939145_01_fped-06-00123-g0001.jpg
F1
A representative picture of these histological findings is shown in Figure 1.
PMC5939145_02
Case n.2 histological examination of gastric biopsies. At morphological analysis, fundic mucosa showed mild chronic gastritis, characterized by complete atrophy of the oxyntic glands and pseudopyloric metaplasia (A, H&E stain, 10x). Imunohistochemical staining for chromogranin A of the same biopsy demonstrated linear and micronodular ECL cell hyperplasia (B, chromogranin A stain, 10x).
fped-06-00123-g0002.jpg
PMC5939145_02_fped-06-00123-g0002.jpg
F2
A representative picture of these histological findings is shown in Figure 2.