PMC1781429_01
Time course of hematological parameters prior to and after hematopoietic stem cell transplantation (HSCT). Broken lines denote lack of data.
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F3
As illustrated in figure 3, between ages 10 and 11 years the patient's peripheral blood counts showed continuous decline requiring substitution with several erythrocyte concentrates.
Determination of mitogen response (G0/G1) and radiosensitivity (G2/GF) via bivariate flow cytometry. Circles: radiation resistant cases (controls); Triangles: radiosensitive cases (ataxia telangiectasia, AT). Squares: patient blood samples analyzed at different time points prior to (1) and after HSCT (2-7). BMT was performed in May 2002. Immunosuppression following BMT caused lack of mitogen response (time point 2).
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F4
As shown in figure 4, sequential flow cytometric studies of mitogen response vs. radiosensitivity confirmed the replacement of radiosensitive patient cells by radioresistant donor cells.