PMC6256150_01
On the cheek mucosa multiple leukoplasic plaques and multicentic papillomatosis masses covered by a white filing and erosions
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F1
Case 1 - Female, 74 years old, hospitalized for the presence of two vegetant tumoral masses in the left oral commissure, with verrucous surface and an oval keratotic plaque on the semimucosa of the upper lip (Fig.1).
Two vegetant tumoral masses in the left oral commissure, with verrucous surface and an oval keratotic plaque on the semimucosa of the upper lip
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F2
On the cheek mucosa there were present multiple leukoplasic plaques and multicentic papillomatosis masses covered by a white filing and painful erosions (Fig.2).
Squamous epithelium with parakeratosis, acanthosis, papillomatosis, an intraepithelial and dermal acute and chronic inflammatory infiltrate and areas of moderate and severe dysplasia, HE stain, x40
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F3
On the base of pathology report our diagnosis was oral florid papillomatosis. (Fig.3,4).
PMC6256150_02
Exophytic, vegetant, with verrucous surface tumor, placed on the third anterior part of the foot, extending on the inner edge
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F5
Afterwards, starting from that level, it developed an exophytic, vegetant, with verrucous surface tumor, placed on the third anterior part of the foot, extending on the inner edge (Fig.5,6).
Malignant squamous cells, with mature, differentiated appearance, acantholysis aspects and blister formation, with central keratin columns, HE stain, x40
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F7
Intradermic massive chronic inflammatory infiltrate, predominantly composed of lymphocytes and plasma cells, HE stain, x40
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F8
Mitotic activity was minimum, rare atipically mitosis were specially present in the germinal layers, massive chronic inflammatory infiltrate, predominantly composed of lymphocytes and plasma cells, intraepithelial abcess (Fig.8).
PMC6256150_03
Vegetant mass, placed on the right arm with irregular surface, crossed by deep grooves, which contained inner purulent exudate
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F9
The tumor surface was irregular, crossed by deep grooves, which contained inner purulent exudate (Fig.9,10).
Hyperkeratosis, papillomatosis, acanthosis, neoplasic squamous cell looking differentiated, mature, with central keratin columns, HE stain, x40
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F11
After the clinical and the histopathological examination (Fig.11, 12) we have diagnosed papillomatosis cutis carcinoides.
Hyperkeratosis, papillomatosis, acanthosis, neoplasic squamous cell looking differentiated, mature, with central keratin columns, HE stain, x40
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F12
After the clinical and the histopathological examination (Fig.11, 12) we have diagnosed papillomatosis cutis carcinoides.
PMC6256150_04
Vegetant perianal tumor with ulcerated, bleeding and anfractous surface, crossed by deep grooves, many condylomas acuminati peritumoral- preoperator view
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F13
Peritumoral are present many condylomas acuminati (Fig.13).
Postoperator view
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F14
After tumor removal, hemostasis was made by transfixing surgical sutures and a hemostatic bud of the residual cavity was performed (Fig.14).