PMC5641304_01
First case:transverse (Panel A) and longitudinal (Panel B) projections of the lateral crus of the suspensory ligament in zone 3C on an ultrasound image (an arrow indicates the anechoic and hypoechoic zone of the injury). Panels 1A and 1B: on Day 21 after the plasmid DNA (pDNA) was administered. Panels 2A and 2B: on Day 40 after the pDNA was administered. Panels 3A and 3B: on Day 73 after the pDNA administration.
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PMC5641304_01_fvets-04-00168-g001.jpg
F1
AAEP 5-score lameness scale). A marked an- and hypoechoic zone (with an area of 0.6 cm2) in the lateral part of the lateral crus of the suspensory ligament was visualized within area 3B-3C on an ultrasound examination of the injured limb (Figure 1: Panels A and B). A further increase of echogenicity in the region of injury could be seen on an ultrasound image; however, a "scar:collagenous" change of the injured ligament was hardly visualized (Figure 1: Panels 3A and 3B).
PMC5641304_02
Second case:transverse (Panel A) and longitudinal (Panel B) projections of the superficial digital flexor tendon in zone 2B on an ultrasound image (an arrow indicates an anechoic and hypoechoic zone of the injury). Panels 1A and 1B: on Day 21 after the plasmid DNA (pDNA) administration. Panels 2A and 2B: on Day 40 after the pDNA administration. Panels 3A and 3B: on Day 60 after the pDNA administration.
fvets-04-00168-g002.jpg
PMC5641304_02_fvets-04-00168-g002.jpg
F2
A marked an- and hypoechoic zone (with an area of 0.9 cm2) of the lateral part of the superficial digital flexor tendon was visualized in zone 2B on an ultrasound examination (Figure 2: Panels A and B). The site of a tendon injury was hardly seen on an ultrasound image, therefore the damaged tissue had obviously improved (echogenicity increased) (Figure 2: Panels 2A and 2B). The site of a tendon injury was hardly seen on an ultrasound image (Figure 2: Panels 3A and 3B).