PMC6689853_01
Chest CT: solid anterior mediastinal mass measuring 50 x 40 x 35mm in intimate contact with mediastinal vascular structures without cleavage plane and sternal commitment
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Enhanced computed tomography (CT) of the chest revealed a solid anterior mediastinal mass measuring 50 x 40 x 35mm in intimate contact with mediastinal vascular structures without cleavage plane and sternal commitment (Figure 1).
Left image: HyE X 100: basaloid thymic carcinoma, with no lymphovascular invasion; right image: p53 determination (immunohistochemistry)
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Histology demonstrated a basaloid thymic carcinoma, with no lymphovascular invasion (Figure 2).
Chest CT: downsizing of the mediastinal; remains in close contact with vascular structures without a clear separation line with no sternal involvement; PET-TC: not FDG accumulation in remaining tissue
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After completing treatment, a new CT (Figure 3) showed a significant downsizing of the mediastinal mass with approximately an 81% reduction in tumor size. The differential diagnosis between non neoplastic fibrosis and remaining tumor was not definitive as the PET scan did not show FDG accumulation and the cost-effectiveness of a surgical exploration was not considered favourable (Figure 3).