PMC7309598_01
(A-E) Post contrast venous phase CT images (A-D) and gross anatomy (E). The prostate shows heterogeneous enhancement in this mid-prostate cross section image (A). In the cross sectional image dorsocranial to the prostate (B), a hypoattenuating oval tubular structure with peripheral contrast enhancement is present consistent with the body of the uterus and a second smaller tubular structure dorsally and to the left consistent with the left horn (arrow). A urethra is also shown in the figure (arrowhead). More cranially, both uterine horns are visible, the right with severely increased volume and both with a wavy appearance (C). The dorsal reconstruction shows both horns (D). The specimen (E) shows the prostate with a urethral catheter, the body of the uterus (short arrow), and the two uterine horns (long arrows).
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F1
Nucleoli were prominent, and mitotic figures were also commonly observed (0-2/HPF).
(A-D) Uterus masculinus. Histopathological and immunohistochemical findings. (A) Neoplastic cells arranged in micropapillary projections. Scattered, mononuclear inflammatory cells are seen within the surrounding stroma (hematoxylin and eosin stain). Strong and specific immunoreactivity for cytokeratin-7 (B) and vimentin (C) is demonstrated inside the cytoplasm of neoplastic cells. Immunolabeling for estrogen receptor alpha is also observed inside the nuclei of smooth muscle cells (D).
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F2
Nucleoli were prominent, and mitotic figures were also commonly observed (0-2/HPF). The arrangement of neoplastic cells varied throughout the mass, from solid to cystic-papillary in appearance (Figure 2A). On immunohistochemistry, neoplastic cells were positive for cytokeratin-7 (Dako Omnis, clone OV-TL 12/30; Figure 2B) and vimentin (Dako Omnis, clone V9; Figure 2C); moreover, smooth muscle cells and occasional neoplastic cells showed nuclear immunoreactivity for estrogen receptor alpha (Dako Omnis, clone EP1; Figure 2D).