PMC6174357_01
Lymphocyte counts during corticosteroid therapy. Total lymphocytes count was measured at diagnosis (05/2014) until the end of patient follow-up. Steroid treatment, started on May 2014, led to severe lymphopenia; but, immunosuppressive therapy withdrawal on March 2015 resulted in normal lymphocyte count. The intermittent line indicates the lower range of normal lymphocyte count.
fped-06-00272-g0001.jpg
PMC6174357_01_fped-06-00272-g0001.jpg
F1
The laboratory tests showed normal white cell counts, except for marked lymphopenia (Figure 1), reduction of CD4+ cells (ranging from 50 to 300 cells/muL), increase of fetal hemoglobin, (6.4-13.9% during follow-up), supposedly related to reticulocytosis. After corticosteroid tapering the patient's total numbers of lymphocytes gradually increased and reached normal levels (Figure 1).