PMC9893990_01
a Axial contrast-enhanced T1 image, showing a contrast-enhancing lesion in the left cingulate gyrus. b T2-weighted axial image. c Sagittal contrast-enhanced T1 image.
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F1
An MRI was obtained on the same day, which showed a tubular, contrast-enhancing lesion in the left cingulate cortex (shown in Fig. 1).
a Sagittal T2 image of a tumor ranging from Th7 to Th12, significantly compressing the spinal cord ventrally. b Axial T2 image of nodular tumor manifestation at conus medullaris and filum terminale.
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F2
This MRI revealed a spinal cord tumor ranging from Th7-Th12 with an additional nodular tumor mass in the conus medullaris, as well as signs of meningeal carcinomatosis (shown in Fig. 2).
Histological and immunohistochemical examination of a biopsy specimen of the nodular lesion on the filum terminale. a H&E staining showing infiltrating and nodular proliferation of pleomorphic cells with hyperchromatic nuclei and scant cytoplasm. b H&E staining, higher magnification. c KI-67 staining, a nuclear protein that is associated with cellular proliferation. d Specimen with S-100 staining.
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F3
H&E staining showed significant cell proliferation with enlarged cell nuclei, staining with KI-67, which is a marker of proliferation, revealed an increased fraction of proliferation (shown in Fig. 3).