PMC5437999_01
Extensive lysozyme deposition within the kidney interstitium, perivascular region and the glomeruli (brown color indicates areas of lysozyme tissue infiltration).
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Figure1
Ratio 1.01). Renal biopsy with semi-quantitative immunohistochemical staining was negative for IgG, IgA, IgM, kappa, lambda, C3c, and C1q but was strongly positive for lysozyme in the interstitium and peri-vascularly, and weakly positive in the glomerular space, confirming the diagnosis of lysozyme amyloidosis (Figure 1).
CT-Abdomen demonstrating spontaneous intra-hepatic hemorrhage, measuring 8.15 cm x 5.46 cm.
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Figure2
Interestingly, he had also developed two spontaneous liver hematomas (8.15 x 7.7 x 1.9 cm and 8.2 x 5.5 x 7.2 cm), spontaneous left adrenal hemorrhage (5.2 x 3.4 x 2.5 cm), as well as large mesenteric lymph nodes consistent with spontaneous intra-nodal hemorrhage (7.2 x 4.6 cm) (Figure 2).