PMC7158929_01
External eye photography revealed bilateral corneal well-defined, elevated, whitish opaque lesions (OU), the left eye (b) was more severe than the right eye (a). Under high-power magnification, the lesion had a glistening appearance without vascularization (c)
TJO-10-58-g001.jpg
PMC7158929_01_TJO-10-58-g001.jpg
F1
The right eye had three dot-like lesions over the para-centered cornea, whereas the left cornea had a band-like opacity and multiple satellite lesions near the main lesion; however no stromal infiltration or anterior chamber reaction could be traced [Figure 1].
The anterior segment optical coherence tomography of the left eye revealed that the corneal lesion expressed a hyperplastic epithelium with Bowman's layer disruption, and mild edematous stroma, which had increased thickness and loss of normal lamellar appearance. The Descemet's membrane and endothelium were intact during this examination
TJO-10-58-g002.jpg
PMC7158929_01_TJO-10-58-g002.jpg
F2
Anterior segment optical coherence tomography (ASOCT) revealed that the left eye's lesion had an irregular hyperplastic epithelium, a disrupted Bowman's layer, and an edematous stroma, which had an increased thickness and loss of normal lamellar pattern [Figure 2].
On the patient's initial visit to the clinic, the corneal topography revealed an irregular astigmatism for the left eye (b). The right eye had a relatively smooth surface (a)
TJO-10-58-g003.jpg
PMC7158929_01_TJO-10-58-g003.jpg
F3
Topography exposed an irregular astigmatism of 2.1 D, which was induced by the elevated lesion and corneal warpage on the left eye [Figure 3], whereas the right eye had a relatively smooth surface.
Series of the obtained images were shown in this figure. (a) The initial presentation of the left eye at the patient's first clinical visit. The lesion extended a little beyond the previous border 3 months later (b). After 1 year of conservative treatment, the lesion's size stayed still but its density became lighter and the tangential curvature became more smooth (c)
TJO-10-58-g004.jpg
PMC7158929_01_TJO-10-58-g004.jpg
F4
Series of the corneal images and the topographies obtained during the follow-up period are shown in Figure 4.