PMC7533238_01
Classic erythematous papules of Stevens-Johnson syndrome present on the trunk and face with sloughing of the epidermis on the cheeks (A). Upper endoscopy images of the esophagus (B), duodenum (C), and flexible sigmoidoscopy image of the colon (D) demonstrate severe concomitant gastrointestinal involvement.
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On hospital day 4, upper endoscopy revealed severe panesophageal inflammation with denuded mucosa, proteinaceous exudates and sloughing of the mucosa with very friable tissue (Figure 1B). Severe duodenitis, with sloughing of the mucosa and proteinaceous exudates, was also noted (Figure 1C). Flexible sigmoidoscopy revealed severe colitis with proteinaceous exudates, denuded mucosa, and membrane formation that extended to the splenic flexure (Figure 1D).