PMC10067467_01
Oral temperature measurements for the patient. This occurred daily for almost the whole course of the disease.
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She also suffered from a daily persistent fever that spiked up to 41 C at midday and had a good response to acetaminophen for a while only to peak up again to 40 C at night (Figure 1).
A photographic image showing the rash (black arrows) and joints swelling (red arrows): (A) on presentation; (B) later in the course of the disease.
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In addition, the proximal interphalangeal joints (PIP) of the first and third fingers of the right hand, all metacarpophalangeal joints, the first and fifth PIPs in the left hand, and both wrists were swollen and tender (Figure 2).
Timeframe of the events in the case.
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With the aforementioned symptoms that persisted for about 60 days (Figure 3) and after excluding all other potential causes, a diagnosis of AOSD was achieved according to Yamaguchi criteria, and subsequent treatment with prednisolone 50 mg daily was started.