PMC6679838_01
Recommended workflow for gastrointestinal toxicities. Abbreviations: CBC: complete blood count; CMP: complete metabolic panel; TSH: thyroid-stimulating hormone; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; C. diff: Clostridium difficile; O&P: ova and parasites; CT: computed tomography; CTLA-4: cytotoxic T-lymphocyte antigen-4; PD-1: programmed death-1.
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fig2
Computed tomography (CT) imaging of the abdomen and pelvis revealed moderate circumferential thickening of the large bowel wall suggestive of pancolitis (Figures 1(a) and 1(b)). More importantly, there was evidence of pneumoperitoneum with a moderate amount of free air in the upper abdomen and a focal disruption noted in the anterior wall of the mid transverse colon which was felt to be the site of perforation (Figure 1(c)).