PMC5470297_01
Radiologic study showed a mass at the same location of former one in temporal lobe
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F1
The radiologic study showed a mass at the same location of former one in temporal lobe [Figure 1]. Radiologic imaging of his brain had been performed and showed a large mass in temporal lobe with solid cystic appearance without significant hemorrhage and minimal peripheral edema and mass effect [Figure 1].
Tumor tissue with normal brain tissue (right upper part). Cellularity is high. Patternless distribution of malignant cells is obvious. (H & E stain, x100)
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F2
H and E study and afterward immunohistochemical (IHC) examination led us to the diagnosis of ATRT. Histomorphologic sections with H and E staining [Figures 2 and 3] showed a highly malignant tumor consists of cells distributed in a patternless fashion and some areas of necrosis.
Histomorphologic view of tumor part shows rhabdoid cells beside spotty necrosis. (H & E stain, x100)
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F3
H and E study and afterward immunohistochemical (IHC) examination led us to the diagnosis of ATRT. Histomorphologic sections with H and E staining [Figures 2 and 3] showed a highly malignant tumor consists of cells distributed in a patternless fashion and some areas of necrosis.
Immunohistochemistry staining for vimentin marker of tumor cells shows positive reaction (H & E stain, x400)
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F4
For confirmation, IHC study was performed that showed positive reaction for vimentin [Figure 4], epithelial membrane antigen, and cytokeratin [Figure 5].
Immunohistochemistry staining for cytokeratin marker of tumor cells shows positive reaction (H & E stain, x400)
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F5
For confirmation, IHC study was performed that showed positive reaction for vimentin [Figure 4], epithelial membrane antigen, and cytokeratin [Figure 5].
Touch preparation cytology of tumor shows noticeable rhabdoid cells (H & E stain, x400)
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F6
Subsequently, we found enough number of typical rhabdoid cells in both samples [Figures 6 and 7].
Frozen sectioning of the brain tumor (H & E stain, x100)
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F7
Subsequently, we found enough number of typical rhabdoid cells in both samples [Figures 6 and 7].