PMC3977155_01
Peripheral blood smear with evidence of intravascular hemolysis.
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A peripheral blood smear contained schistocytes and spherocytes, suggesting hemolysis, and also showed leukoerythroblastosis, with polychromasia, nucleated red blood cells, and immature granulocytes (Figure 1).
Bone marrow biopsy with focal infiltration of adenocarcinoma.
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A bone marrow biopsy revealed poorly differentiated signet ring adenocarcinoma, raising concern for a metastatic gastric cancer (Figure 2).
Wright's stain of bone marrow biopsy demonstrating signet ring cells.
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Biopsy revealed signet ring adenocarcinoma that was histologically similar to both bone marrow and gastric polyp findings, with strong estrogen receptor positivity (Figure 3).