PMC6168664_01
(A) Arthritis of interphalangeal joints of the hands. (B) Ultrasound image of the left knee. Note the presence of synovial fluid (white arrow), marked synovial hypertrophy (white arrowhead) and presence of Power Doppler signal (black arrow), all indicative of active synovial inflammation.
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F1
Following reinstitution of pembrolizumab therapy, bilateral arthritis of the knees, accompanied by arthritis of interphalangeal joints of both hands (Figure 1A), developed after the fifth cycle, Ultrasound of the knees showed evidence of active synovitis (Figure 1B) and a diagnosis of inflammatory polyarthritis was established.