PMC5702861_01
CT scan showing heterogenously enhancing nodular lesion causing destruction of hard palate and alveolar process of maxilla.
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Computed tomography (CT Scan) showed an evidence of heterogenously enhancing nodular oral cavity mass lesion causing destruction of hard palate and alveolar process of maxilla and it was bulging into the nasal cavity (Fig. 1).
CThead showing multiple lytic lesions in calvaria (arrow).
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Further, CT head showed multiple lytic lesions in calvaria (Fig. 2).
Photomicrograph showing diffuse infiltration by plasmablastic cells (H&E- 400x).
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It showed a diffuse infiltration by medium sized tumor cells, of plasmablastic morphology with fine reticular nuclear chromatin, large nucleus, with very little perinuclear hof (Fig. 3).
Immunohistochemistry (200 x) showing strong positivity for kappa, cd 138, Ki67, while CD 20 is negative ruling out plasmablastic lymphoma.
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EBER (ebstein barr virus encoded RNA) was also negative, ruling out the differential of plasmablastic lymphoma (Fig. 4).