PMC3556306_01
Massive shallow ulcers on the left inner thigh surrounded by reddish, infiltrated steak.
1471-2369-14-20-1.jpg
PMC3556306_01_1471-2369-14-20-1.jpg
F1
A 34-year-old man was admitted to our hospital presented with massive shallow ulcers of both lower extremities (Figure 1), fever of 39 C and severe pain.
Light microscopic histological findings of the skin biopsy specimen from the cutaneous lesion showed an inflammatory infiltration containing PAS positive micro-organisms. (Periodic acid-Schiff stain; original magnification: x400).
1471-2369-14-20-2.jpg
PMC3556306_01_1471-2369-14-20-2.jpg
F2
In the end, investigations on the biopsy revealed the existence of C. neoformans after four days of admission (Figure 2) and the capsular polysaccharide antigen titer of C. neoformans in blood determined by latex particle agglutination method was 1:1024.