PMC3263577_01
(a) Erosive plaque on the arm in pemphigus herpetiformis. (b) Arciform pattern of postbullous lesion in pemphigus herpetiformis.
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fig1
On examination, we observed vesicular, bullous lesions, some having clear contents and some being purulent with erosive arciform plaques and crusted lesions (Figures 1(a) and 1(b)).
Histopathologic features. Intraepidermal bulla filled with neutrophils and numerous eosinophils. Single acantholytic cells are seen. Lower epidermis: eosinophilic spongiosis (HE x40) Intraepidermal bulla filled with neutrophils and eosinophils, characteristic of eosinophilic spongiosis (HE x200)
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fig2
The superticia1 and reticular dermis had an inflammatory infiltrate of eosinophile and neutrophile around some of the blood vessels (Figures 2(a) and 2(b)).
(a, b) Direct immunofluorescence. IgG and C3 cell surface deposits throughout the whole epidermis.
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fig3
IgG and complement C3. IgA intercellular deposits on epidermis were not seen (Figures 3(a) and 3(b)).