PMC5618741_01
Anterior central chest wall mass.
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A 43-year-old G6P6 Hispanic female presented with a two-month history of a central chest wall mass (Figure 1). She again sought medical attention only when she experienced intolerable pain and difficulty in swallowing associated with enlargement of a new mass on her chest (Figure 1).
2.1 x 1.5 cm soft tissue infiltrating along the manubrium with underlying destruction of the bone.
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fig2
CT chest/abdomen/pelvis and MRI brain/cervical spine showed extensive infiltration by a soft tissue mass, associated bony destruction, and pulmonary nodules (Figure 2).
HE staining of tumor showing highly cellular epithelial cells with fascicles of short spindle cells.
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fig3
CT-guided core biopsy revealed tumor predominantly composed of spindle cells (Figure 3) with features of SSCC, immunoreactivity for cytokeratin (AE1/AE3), CAM5.2, and vimentin, and weakly positive for muscle actin, S100, and p63.