PMC9674928_01
(A) Axial images chest CT scan which show soft tissue pleural based masses. (B) Axial images of PET/CT scan which show PET avid pleural based masses.
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She was also found to have multiple pleural-based, PET-avid soft tissue lesions in both hemithoraces and a soft tissue nodule in the right lateral chest wall with moderate size right sided pleural effusion (Fig. 1).
Axial images of PET/CT scan which shows significant reduction of the PET activity pleural based masses.
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(A and B) section shows diffuse plasma cell proliferation composed of mixture of mature and immature plasma cells. Mature plasma cells have eccentric nuclei, clumped clock face chromatin pattern, and perinuclear hof (black arrows). Immature cells are variable in size with higher N:C ratio, bizarre nuclei, multinucleation and macronucleoli (blue arrows). Mitotic activity is present (yellow arrow). (H&E stain, x 40.
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(A and B) Axial images of PET/CT scan which shows significant reduction of the PET activity pleural based masses.
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A repeat PET scan after 6 months and after about 7 cycles of VPD therapy showed Interval diminution in PET activity in multiple bony foci, pleural based areas, left lung, cervical lymph node and right lateral chest wall consistent with a positive response to therapy (Fig. 4A and B).