PMC10174228_01
Colon endoscopy showing diffusely inflamed and ulcerated mucosa of transverse colon.
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F1
Endoscopy was performed and revealed a large ulceration in the transverse colon encompassing the whole circumference of the colon (Figure 1).
(A) Severe mucosal injury with acute inflammation within the bowel wall. Note the sevelamer crystal within the luminal debris. (H&E, 40x). (B) Sevelamer crystal within the luminal debris:characteristic fish scale appearance with orange and pinkish hue (H&E, 200x).
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F2
The histopathological finding of the colon described severe mucosal injury with acute inflammation and visible characteristic "fish-scale" crystals of sevelamer within the luminal debris, accompanied by acute inflammation and focal necrosis of the bowel wall, with no signs of dysplasia or malignant alteration (Figures 2A, B).