PMC8169267_01
Multiple, discrete, 1-2 mm shallow ulcers with heaped-up edges in the distal esophagus.
CRIGM2021-5519635.001.jpg
PMC8169267_01_CRIGM2021-5519635.001.jpg
fig1
At EGD, there were multiple, discrete, 1-2 mm shallow ulcers with heaped-up edges in the distal esophagus (Figure 1).
Margination, multinucleation, and moulding consistent with HSV infection.
CRIGM2021-5519635.002.jpg
PMC8169267_01_CRIGM2021-5519635.002.jpg
fig2
Proximal, mid, and distal esophageal biopsies revealed margination, multinucleation, and moulding consistent with HSE (Figure 2).
Presence of eosinophils (20/hpf), eosinophilic microabscesses, and eosinophil degranulation and Bazel zone hypertrophy.
CRIGM2021-5519635.003.jpg
PMC8169267_01_CRIGM2021-5519635.003.jpg
fig3
Additionally, there were 20 eosinophils/hpf (Figure 3) along with eosinophil microabscesses, extracellular eosinophil granules, and Bazel zone hypertrophy.