PMC1297610_01
Course of core body temperature in a patient with heat stroke. The red line denotes the core body temperature while using 'conventional' temperature control methods. The blue line denotes the core body temperature while using an endovascular (CoolGard ) cooling treatment. Blue arrows denote the start of CoolGard  treatment. Red arrows denote attempts to terminate the active cooling procedure.
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Bair Hugger  (Arizant Healthcare Inc, Eden Prairie, MN, USA), which were applied for 8 h, did not lead to any significant decrease in core body temperature (Figure 1). Because of subsequent deterioration of the patient's condition and insufficient conventional temperature control, an aggressive treatment approach with a novel intravascular cooling system (CoolGard 3000  and Cool Line , Alsius, Irvine, CA, USA) was begun. Core body temperature was maintained at about 37 C and subsequently maintained at 37.5 C (+- 0.2 C) with the use of the intravascular catheter over the next 5 days (Figure 1). Several attempts to stop the active cooling within this period (Figure 1) led to an immediate steep increase of core body temperature, which forced us to prolong this very efficacious endovascular treatment.