PMC4753742_01
PMC4753742_02
Mucosal ulcers. (a) oral mucosal aphthous ulcers, (b) penile ulcer
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F1
During this period, he had recurrence of oral ulcers and a large genital ulcer [Figure 1] which was apparently present for few days prior to reporting to us.
Photomicrograph of renal biopsy. (a) light microscopy, (b and c) glomerulus showing mesangial proliferation and neutrophilic infiltrates, (d) immunofluorescence showing abundant peripheral and mesangial C3 deposits
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F2
Renal biopsy showed 3 glomeruli with increased mesangial matrix and cellularity with focal infiltration of the tuft with few neutrophils [Figure 2]. Immunofluorescence study showed abundant peripheral and mesangial deposits of C3c [Figure 2] and mild deposit of IgM in the glomeruli and C4d stain was negative.
Photomicrograph of the mucosal ulcer. (a) light microscopy showing subepithelial vascular proliferation, (b) perivascular lymphocytic infiltration with scattered neutrophilic infiltrates
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F3
He underwent biopsy of the oral ulcer, which showed subepithelial vascular proliferation, and perivascular lymphocytic infiltration along with scattered neutrophils, consistent with vasculitis [Figure 3].