PMC4039399_01
Fundus photographs taken at age 1 year and 4 months.. Notes: (A) Right eye. (B) Left eye.
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The fundus examination of both eyes showed round-shaped sharply-demarcated atrophic lesions involving the macula with large choroidal vessels and the bared sclera at the base (Figure 1).
Fundus photographs taken at age 4 years and 1 month.. Notes: (A) Right eye. (B) Left eye. The white crosses show the fixation points.
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TNO stereo test and Titmus Stereo Test. The fundus examination showed no significant changes except for some pigmentation in the atrophic lesions (Figure 2). Examination of fixation behavior by visuscope showed steady fixation in the normal area close to the nasal edge of the atrophic lesion bilaterally (Figure 2).
SD-OCT images at age 4 years and 1 month.. Notes: (A) Right eye. (B) Left eye. (A and B) ILM-RPE map on the macular cube 200x200. Cross points of vertical and horizontal lines show fixation points (white crosses). (C) B-scans. The bars show the fixation points (white arrows).. Abbreviations: ILM-RPE, internal limiting membrane - retinal pigment epithelium; SD-OCT, spectral domain optical coherence tomography.
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The SD-OCT (Cirrus HD-OCT; Carl Zeiss Meditec AG, Jena, Germany) showed a crater-like depression accompanying atrophic neurosensory retina, and the absence of the retinal pigment epithelium and choroid (Figure 3). IS/OS junction line (Figure 3). In addition, it was not difficult to get the SD-OCT images on him with dilated pupil and without any anesthesia.