PMC6699319_01
(a)-(b) Colour fundus photography showed arteriolar attenuation, peripapillary atrophy, optic disc pallor, macular hemorrhage and typical retinal pigment deposits (bone spicules) involving the mid-peripheral retina (c) Indocyanine green angiography (ICGA) revealed a well-distinct "triangular shape" area of intense hypercyanescence ("hot spot") corresponding to the neovascularization (d) B-Scan optical coherence tomography angiography revealed high-flow intraretinal neovascularization originated in the superficial layer descending into a tuft-shaped lesion toward the sub-RPE space. (e)-(h) Optical Coherence Tomography Angiography images (6 x 6 mm) revealing the progression of the tuft-shaped lesion from the superficial layer to choroid capillary. (e) Superficial capillary plexus segmentation. (f) Deep capillary plexus segmentation. (g) Outer retinal layer segmentation. (h) Choriocapillaris segmentation. (i)-(j) Spectral Domain-Optical Coherence Tomography at baseline. (k)-(l) Spectral Domain-Optical Coherence Tomography after treatment.
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fig1
(a)-(d) Optical coherence tomography angiography images (6 x 6 mm) revealed the progression of the tuft-shaped lesion from the superficial layer to choroid capillary. (a) Superficial capillary plexus segmentation. (b) Deep capillary plexus segmentation. (c) Outer retinal layer segmentation. (d) Choriocapillaris segmentation. (e)-(f) B-Scans optical coherence tomography angiography showed clearly two distinct intraretinal neovascularizations originated in the superficial layer descending into a tuft-shaped lesion toward the sub-RPE space, respectively above (e) and under (f) the fovea. (g)-(h) Spectral Domain-Optical Coherence Tomography at baseline. (i)-(j) Spectral Domain-Optical Coherence Tomography after treatment.
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fig2
OCTA imaging. OCTA showed clearly two distinct intraretinal neovascularizations located in the segmentation of choroid capillary, both bordering the sub-RPE space (Figure 2).