PMC6350262_01
Chest X-ray and chest plain computed tomography. A: Chest radiograph on admission shows bilateral ground glass opacities. B, C, D. Chest CT scan shows random ground glass opacities in the lower lung fields. Honeycombing and pleural effusion are not present.
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Chest radiographs showed bilateral ground glass opacities (Fig. 1A). Honeycombing and pleural effusion were not observed (Fig. 1B, C, D).
Cellulo-myxomatous alveolitis. The photomicrograph with HE staining shows notable inflammatory cell infiltration of the alveolar wall with reactive pneumocyte hyperplasia (scale bar, 10mum).
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The alveolar wall was enlarged with the infiltration of inflammatory cells and epithelial atypia and exfoliation, suggesting severe epithelial injury (Fig. 2).
Cellulo-myxomatous alveolitis with desquamative pneumocytes and fibrinous exudates. Photomicrograph of lung sections with HE and Alcian blue/PAS staining shows mixed cellulo-myxomatous change of alveolar wall with pneumocyte hyperplasia and fibrinous exudates (arrows). High power view shows findings of desquamative and atypical pneumocytes (black arrow head) with some eosinocyte infiltrations (blue arrow head) (scale bar, 100mum).
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Alcian blue Periodic acid-Schiff staining revealed collections of fibroblasts stained blue suggesting early fibrosis (Fig. 3).
Disease course of the patient over time.
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The patient's clinical course is shown in (Fig. 4).