PMC5734690_01
Left lung lesion seen on PET (left) and CT Chest (right).
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This was further evaluated with a chest CT scan that confirmed a 2cm left upper lobe lung mass (Fig. 1).
(A) Left upper lobe wedge resection of the lung with 2.2 cm nodule of tumor (H&E, original magnification 100x); (B) High power image of left upper lobe tumor with lepidic and acinar growth pattern in the pulmonary parenchyma (H&E, original magnification 200x); (C) TTF-1 immunohistochemical stain of pulmonary tumor, consistent with lung primary (TTF-1, original magnification, 200x).
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On final pathology, the nodule was interpreted as primary pulmonary adenocarcinoma (Fig. 2).
(A) Wedge resection of the left lung lower lobe revealed a 0.3 cm, well circumscribed tumor nodule (H&E, original magnification 150x); (B) The nodule was negative for TTF-1 and positive for prostate specific antigen (PSA) (PSA immunohistochemical stain, original magnification 150x); (C) The nodule displayed similar coalescing glands with round nuclei and inconspicuous nucleoli, similar to the tumor morphology of the initial prostatic resection, confirming the diagnosis of concomitant metastatic prostatic adenocarcinoma (H&E, original magnification 200x).
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The wedge resections contained nodules positive for PSA and were interpreted as metastatic prostatic adenocarcinoma (Fig. 3).