PMC9282727_01
Gadolinium-enhanced T1-weighted MR images (a and b) before apoplexy, (c and d) after pituitary apoplexy, and (e and f) after surgery.
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F1
Magnetic resonance imaging (MRI) revealed a dumbbell-shaped tumor (22 x 17 x 11 mm) pushing the optic chiasm upward and unobstructed hydrocephalus [Figures 1a and b]. Coma Scale (GCS) score was 12 (E3V3M6) and he became somnolent. Computed tomography (CT) showed a high-density area on the pituitary gland and MRI showed enlargement of the upper part of the tumor (24 x 18 x 18 mm) [Figures 1c and d]. MRI after surgery showed satisfactory decompression [Figures 1e and f].
Carcinoma cells from pituitary tumor (a) Tumor tissue with papillary structures, intranuclear inclusions, and nuclear grooving are observed. HE. (b) Tumor cells showed strong immunopositivities to TTF-1.
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F2
An immunohistochemical test reported positive TTF1 and 25% MIB-1 [Figures 2a and b].