PMC3325753_01
Histology of the conjunctival tumor. Malignant epitheloid cells are seen. Brown pigment was present. These features are suspicious of conjunctival melanoma. Haematoxylin & Eosin, x200.
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F1
A biopsy was taken, and the biopsy showed malignant epithelioid cells with brown pigment deposition (Figure 1).
The tumor cells are positive for S100 protein. Immunostaining, x200.
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F2
Immunohistochemically, the tumor cells were positive for S100 protein (Figure 2), HMB45 (Figure 3), p53, Ki-67 (labeling=30%), KIT (Figure 4) and PDGFRA (Figure 5).
The tumor cells are positive for HMB45. Immunostaining, x200.
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F3
Immunohistochemically, the tumor cells were positive for S100 protein (Figure 2), HMB45 (Figure 3), p53, Ki-67 (labeling=30%), KIT (Figure 4) and PDGFRA (Figure 5).
The tumor cells are positive for KIT protein. Immunostaining, x300.
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F4
Immunohistochemically, the tumor cells were positive for S100 protein (Figure 2), HMB45 (Figure 3), p53, Ki-67 (labeling=30%), KIT (Figure 4) and PDGFRA (Figure 5).
The tumor cells are positive for PDGFRA. Immunostaining, x300.
rt-2012-1-e8-g005.jpg
PMC3325753_01_rt-2012-1-e8-g005.jpg
F5
Immunohistochemically, the tumor cells were positive for S100 protein (Figure 2), HMB45 (Figure 3), p53, Ki-67 (labeling=30%), KIT (Figure 4) and PDGFRA (Figure 5).