PMC9197607_01
Image (a) showing diffuse proliferative glomerulonephritis, reduced bowman space (green arow) and increased cellularity in glomeruli (orange arow). Image (b) showing global glomerular basement membrane duplication (yellow arrow). Image (c) showing cortical scarring (blue arow).
CRIHEM2022-2497380.001.jpg
PMC9197607_01_CRIHEM2022-2497380.001.jpg
fig1
She underwent a renal biopsy which revealed diffuse proliferative glomerulonephritis with prominent membranoproliferative features as seen on Figure 1.
Image (a) showing immunofluorescence (IF) staining for immunoglobulin G 3 (IG3), green representing the signal for IG3 (blue arow), with the nuclei in blue pointed with the gray arow. Image (b) showing IF staining for lambda, green representing the signal (red arow), with the nuclei in blue pointed with the yellow arow.
CRIHEM2022-2497380.002.jpg
PMC9197607_01_CRIHEM2022-2497380.002.jpg
fig2
Figure 2. Findings were consistent with proliferative glomerulonephritis with monoclonal IgG deposits, and a diagnosis of monoclonal gammopathy of renal significance was then made.