PMC7813656_01
PMC7813656_02
HEX Obj 20 Double mesenchymal and vascular proliferation (A) made of fascicular spindle cells in nuclei bloated with some cytonuclear atypia and dilated vessels with a thickened and hyalinized wall (B) (HEX Obj 40)
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F1
The mesenchymal component was made of fascicular spindle cells in nuclei bloated with some atypical cytonuclear and few mitotic figures, while the vascular component was made of dilated vessels with a thickened and hyalinized wall (Figure 1).
HEX Obj 40 Immunohistochemistry findings showing positive staining to CD34 (A) and HHV8 (B)
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F2
On immunohistochemistry examination, tumor cells were CK (-), vimentin (+), CD34 (+), CD31 (+), actine (-), desmin (-), PS100(+/-), with positive nuclear staining to Human Herpes Virus 8 (HHV8) (Figure 2).
axial (A), coronal (B) and sagittal (C) CT scan images showing a large mass arising from the false vocal cord and extending to supra and subglottis
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F3
Computed tomography (CT) scan revealed a large mass (4.7cmx2.3cm) arising from the left false vocal cord and extending to sub and supraglottic regions, with involvement of thyroid cartilage (Figure 3).