PMC7234350_01
(H&E): (A) Histological examination showed a neoplasm composed of mature adipocytes (a), adrenal cortex (b), and hematopoietic elements (c) (5x), (B) Trilineage hematopoiesis with erythroid precursors, myeloid cells, and megakaryocytes (40x), and (C) Benign adipose tissue and hemorrhage within the adrenal gland parenchyma (5x).
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Microscopic sections showed multiple islands of hematopoietic cells with trilineage maturation admixed with benign adipose tissue within the adrenal parenchyma, consistent with a myelolipoma and focal areas of hemorrhage (Figure 1(a)-(c)).
(a) Spindle cell lesion with nuclear palisading/Verocay bodies (arrows; 5x), (b) Verocay bodies (40x), and (c) staining positive for S100 (5x).
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In addition, a focus adjacent to the myelolipoma, of interlacing fascicles of spindle cells with nuclear palisading (Verocay bodies), was seen, staining positive for S100 by immunohistochemistry, and was subsequently identified as a schwannoma (Figure 2(a)-(c)).