PMC7519980_01
Photograph of the patient on (a) Day 17 of use polymyxin B and (b) Day 60 after the withdrawal of polymyxin B. A 68-year-old man received polymyxin B therapy for a Klebsiella pneumoniae blood infection. With treatment, the patient had progressive hyperpigmentation (a) that significantly faded after the polymyxin B was withdrawn (b).
CRIM2020-6461329.001.jpg
PMC7519980_01_CRIM2020-6461329.001.jpg
fig1
Seven days after the withdrawal of polymyxin B, the color of the patient's face and neck was completely black (Figure 1(a)). Sixty days after the withdrawal of polymyxin B, the hyperpigmentation of the patient's face and neck skin was almost entirely resolved (Figure 1(b)).