PMC5961133_01
A chick pea- size ulcerated tumor mass almost occluding the entrance of the left ear canal.
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F1
Bean-sized hard ulcerated masses were removed surgically under general anesthesia and were processed for light microscopic examination (Fig. 1).
Distended ductules with their lumen largely occupied by proliferating neoplastic epithelium. These ductules were separated by interrupted layers of myo- epithelium. Inset: epithelial intracytoplasmic cerumen pigment-containin.
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F2
Most of those ductules were completely obliterated by the proliferating neoplastic epithelial cells (Fig. 2) but others displayed sieve-like cribriform or comedo patterns when centrilobular core of epithelial necrosis existed (Fig. 3&4).
Invasion of neoplastic epithelial cells in the stroma. These cells are Pleomorphic and hyperchromatic and displayed poor acinar arrangement (H&E , x10).
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F5
Criteria of carcinogenesis were most evident on glandular epithelial cells which invaded the stroma and the lymphatics (Fig. 5&6).
Adenomatous irregularly dilated glandular acini containing sloughed folded and fragmented epithelium (H&E, x10).
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F7
They were irregularly dilated with folded hyperplastic epithelium (Fig. 7).