PMC8180858_01
Brain MRI at admission (A-E). (A, B) Axial view (weighted sequence in T1, T2). (C-E) Sagittal, coronal, axial view after contrast injection, with the tumor marked. (F, G) Brain MRI after surgery. (H) Pancreatic cysts.
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After gadolinium administration, a well-circumscribed enhancing lesion was observed ( Figures 1A-E ). Abdominal computed tomography (CT) was also performed to identify associated lesions and pancreatic cysts ( Figure 1H ). Postoperative MRI ( Figures 1F, G ) demonstrated that the lesion in the suprasellar region was completely removed.
Representative postoperative pathological images. (A) Histologic examination of optic nerve HGB. (B-F) Immunohistochemical staining. (B) The proliferative fraction of tumor cells (Ki-67) was low, at approximately 2%. (C) CD-34 showed abundant blood vessels. Tumor cells showed positivity for EGFR (D), NSE (E) and vimentin (F).
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He underwent surgery to remove the tumor from the suprasellar region at our neurosurgical department, and histology confirmed the diagnosis of HGB ( Figures 2  and  3 ). Furthermore, the neoplasm was positive for EGFR, NSE, CD34 and vimentin and negative for CK-pan, Pax-8, CD10, CD56, S-100, glial fibrillary acidic protein, inhibin, SSTR2, and epithelial membrane antigen ( Figure 2 ).
Surgical pictures. Severe adhesion of the tumor and left optic nerve.
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He underwent surgery to remove the tumor from the suprasellar region at our neurosurgical department, and histology confirmed the diagnosis of HGB ( Figures 2  and  3 ).