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Computed tomography of the chest at the onset of COVID-19. A view of the bilateral lower lungs shows ground-glass opacity.
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One week later, he developed slight dyspnea and cough, and computed tomography (CT) revealed ground-glass opacity in his lungs bilaterally, which suggested SARS-CoV-2 infection (Fig. 1).
Bone marrow findings during cytopenia. The marked appearance of hemophagocytic macrophages is demonstrated.
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Occasionally, a proliferation of macrophages demonstrating phagocytosis of hematopoietic cells was evident (Fig. 2).
(a) Blood cell count during the clinical course. Thick black, white, and thin arrows indicate the infusion of red blood cells, platelets, and granulocyte-stimulating factor, respectively. (b) Immunological parameters during the clinical course. Day 0 indicates the diagnosed date of COVID-19.
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T cell counts after vaccination (Fig. 3b). The patient is now in remission, as confirmed via CT, and is scheduled to receive high-dose chemotherapy combined with autologous stem cell transplantation.