PMC3876639_01
Radiograph of left scapula and shoulder region showing a well-defined lytic zone, without involvement of soft tissue
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F1
X-ray revealed a large lytic lesion in the left scapula, without soft tissue extension [Figure 1].
FNAC smear showing small groups of malignant cells with well-defined cell borders, dense eosinophilic cytoplasm, high N/C ratio, nuclear pleomorphism and nucleoli (H and E, x500)
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F2
The cells were large, about 60 mu, with well-defined borders, abundant dense eosinophilic cytoplasm, pleomorphic nuclei with high N/C ratio and prominent nucleoli [Figure 2].
Tissue section showing malignant cells arranged in cell balls and peudoglands, separated by finely vascularized stroma (H and E, x250)
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F3
Formalin - fixed Haematoxylin and Eosin stained sections showed round to polyhedral cells arranged in the form of trabeculae, cell balls and pseudoglands separated by fine vascularized septa [Figure 3].
Tissue section showing positive immunostaining for AE-1/AE-3 (a) and CK 7 (b) (x125)
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F4
The AE-1/AE-3 and CK-7 stains were strongly positive, while CK-20 was negative [Figures 4a,b].