PMC7495167_01
Computed tomography of the cranium showing a posterior scalp mass at the midline near the convexity: (a) sagittal view; (b) transverse view: 3.7 cm at the greatest dimension.
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fig1
A CT scan of the brain with contrast revealed a posterior scalp mass at the midline near the convexity, which was inseparable from the calvarium (3.7 cm at the greatest dimension; Figure 1).
(a) Cords and nests of tumor cells are surrounded by dense fibrotic stroma and adipose tissue; hematoxylin-eosin, original magnification x40. (b) The meningothelial cells are spindly looking with pink cytoplasm. Cells are packed together forming syncytial structures and whorls; hematoxylin-eosin, original magnification x200. (c) Tumor cells show strong and diffuse cytoplasmic staining with vimentin (magnification x100), (d) weak to moderate cytoplasmic and nuclear staining with S-100 (magnification x100), and (e) focal weak to moderate nuclear staining with progesterone receptor (PR) (magnification x100).
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fig2
Cells were spindly looking with moderate amount of amphophilic cytoplasm, arranged in cords and nests, separated by a thick collagenous stroma and adipose tissue (Figure 2(a)). The nuclei showed relatively bland features with fine chromatin and indistinct nucleoli (Figure 2(b)). Tumor cells were immunohistochemically strongly positive for vimentin (Figure 2(c)) and weakly positive for S-100 (Figure 2(d)) and progesterone receptor (PR) (Figure 2(e)), while negative for AE1/3, CAM 5.2, EMA, HMB-45, Melan-A, and SMA.
Sebaceous glands contiguous with the cyst wall. Hematoxylin-eosin, original magnification x40.
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fig3
Histologically, this anterior scalp mass showed a cystic lesion with sebaceous glands adjacent to the cyst wall (Figure 3).
PMC7495167_02