PMC8077665_01
A Coronal section of the CT chest showing right lower lobe mass abutting adjacent lung, mediastinum and diaphragm below. B Gross appearance of the mass (>15 cm) post resection.
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F1
A CT chest/abdomen/pelvis was performed, which revealed a large heterogeneous mass within the lower lobe of the right lung (shown in Fig. 1A). She underwent surgical resection of the thoracic mass (shown in Fig. 1B).
A Low power showing well-circumscribed, encapsulated proliferation of spindle cells with staghorn vascularity (thick arrow) and areas of hyaline degeneration (thin arrow) but no necrosis. B Staghorn vessels with spindle cells showing mild to moderate nuclear atypia. C Up to 4 mitoses per high-power field. D Strong and diffuse nuclear positivity for STAT6.
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F2
Fig. 2A-C). Further immunohistochemistry analysis revealed the cells were positive for STAT6 (signal transducer and activator of transcription 6) and CD34 (shown in Fig. 2D; Fig. 3).