PMC8543100_01
Photograph showing the ulceroproliferative lesion with indurated margins in the mandibular anterior gingiva.
DRJ-18-80-g001.jpg
PMC8543100_01_DRJ-18-80-g001.jpg
F1
The lesion was extending labiolingually from labial attached gingiva to lingual attached gingiva and mesiodistally from mandibular left canine to mandibular right first premolar region [Figure 1].
Photomicrograph showing connective tissue stroma showing along with island and sheets made of basaloid cells invaded into connective tissue (H and E stain, x4).
DRJ-18-80-g002.jpg
PMC8543100_01_DRJ-18-80-g002.jpg
F2
Invaded epithelial cells were in the form of nests, islands, and sheets composed of basaloid cells showing hyperchromatic large nuclei and indistinct cytoplasm [Figures 2 and 3].
Photomicrograph showing hyperchromatic large nuclei and indistinct cytoplasm (H and E stain, x40).
DRJ-18-80-g003.jpg
PMC8543100_01_DRJ-18-80-g003.jpg
F3
Invaded epithelial cells were in the form of nests, islands, and sheets composed of basaloid cells showing hyperchromatic large nuclei and indistinct cytoplasm [Figures 2 and 3].
Photomicrograph showing areas of comedonecrosis in between the sheets of cells (H and E stain, x40).
DRJ-18-80-g004.jpg
PMC8543100_01_DRJ-18-80-g004.jpg
F4
Areas of comedonecrosis were seen in between the sheets of cells [Figure 4].
Photomicrograph showing positivity for pan-cytokeratin AE/AE3. (immunohistochemical stain, x10).
DRJ-18-80-g005.jpg
PMC8543100_01_DRJ-18-80-g005.jpg
F5
The negative results of PAS and positive for pan-cytokeratin [Figure 5] lead to the final diagnosis of BSCC.