PMC3010627_01
Computerized tomography detected a 43 x 37 x 31-cm tumor in the right retroperitoneum, and the right kidney was deflected greatly to the left ventral side (white arrow).
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A CT scan detected a 43 x 37 x 31 cm tumor in the right retroperitoneum, with the right kidney significantly displaced to the left and anterior side (Figure 1).
Chest X-ray showed that elevation of the diaphragm due to rapid growth of retroperitoneal tumor and cardiac enlargement.
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His condition was diagnosed as respiratory failure due to elevation of the diaphragm as a consequence of the rapid growth of the tumor (Figure 2).
Intra-operative findings. The retroperitoneal tumor weighing 22 kg was extirpated.
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Pathological examination showed that the resected mass weighed 22 kg and was 45 x 40 x 30 cm in size (Figure 3).
Histopathological findings of the tumor diagnosed dedifferentiated liposarcoma (HE stain, original magnification x200). (a) Most of the tumor cells consisted of spindle cells with high-grade atypia. (b) Some of which were identified to be lipoblasts in a myxoid background.
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Histopathologic analysis demonstrated many spindle cells with high-grade atypia; some of which were lipoblasts on a myxoid background; there were no split signals on FISH analysis using CHOP DNA probes, thus leading to the diagnosis of dedifferentiated liposarcoma (Figure 4).