PMC8257023_01
Treatment regimens and CSF cell counts.
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The WBC count increased to 17.17x109/L, and the first routine and biochemical tests of cerebrospinal fluid (CSF) showed significant increases in cell count, proportion of multinucleated cells, protein level (Figures 1 and 2), and slight decrease in sugar level (Figure 2), leading to a diagnosis of possible intracranial bacterial infection. CRP tests showed decreased WBC count and CRP. CSF routine and biochemical tests showed that cell count and protein level decreased significantly compared with previous results (Figures 1 and 2). CSF WBC was 0.079x109/L, the concentration of protein in CSF was 737 mg/L, and the concentration of sugar in CSF was 3.43 mmol/L. CSF routine and biochemical tests showed that cell count, proportion of multinucleated cells and protein level further decreased (Figures 1 and 2). CSF WBC was 0.569x109/L, the concentration of protein in CSF was 1089 mg/L, and the concentration of sugar in CSF was 5.06 mmol/L. CSF examination showed turbid CSF with elevated WBC count (Figure 1), increased proportion of multinucleated cells, and elevated protein level compared with previous tests (Figures 1 and 2), leading to the conclusion that the infection aggravated again. The results of CSF routine and biochemical tests showed significant improvement (Figures 1 and 2), and Staphylococcus epidermidis was isolated from the CSF culture. On May 24 (d64), routine CSF tests showed normal results (Figure 1). The treatment regimens and CSF cell counts, proportion of multinucleated cells during hospitalization in Department of Neurosurgery are shown in Figure 1.
Treatment regimens and concentration of protein and sugar in CSF.
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The WBC count increased to 17.17x109/L, and the first routine and biochemical tests of cerebrospinal fluid (CSF) showed significant increases in cell count, proportion of multinucleated cells, protein level (Figures 1 and 2), and slight decrease in sugar level (Figure 2), leading to a diagnosis of possible intracranial bacterial infection. CRP tests showed decreased WBC count and CRP. CSF routine and biochemical tests showed that cell count and protein level decreased significantly compared with previous results (Figures 1 and 2). The CSF biochemical tests showed that sugar level elevated to normal (Figure 2). CSF WBC was 0.079x109/L, the concentration of protein in CSF was 737 mg/L, and the concentration of sugar in CSF was 3.43 mmol/L. CSF routine and biochemical tests showed that cell count, proportion of multinucleated cells and protein level further decreased (Figures 1 and 2). CSF WBC was 0.569x109/L, the concentration of protein in CSF was 1089 mg/L, and the concentration of sugar in CSF was 5.06 mmol/L. CSF examination showed turbid CSF with elevated WBC count (Figure 1), increased proportion of multinucleated cells, and elevated protein level compared with previous tests (Figures 1 and 2), leading to the conclusion that the infection aggravated again. The results of CSF routine and biochemical tests showed significant improvement (Figures 1 and 2), and Staphylococcus epidermidis was isolated from the CSF culture. The trends of concentration of protein and sugar in CSF are shown in Figure 2.