PMC6207856_01
High-resolution CT scan (axial cut) of the temporal bone. Total opacification of the left-sided hypo- and mesotympanum by a soft tissue density. Mastoid air cells totally opacified with resorption of septae and partially sclerosed bone. Partial dehiscence of the mastoid portion of the facial nerve canal. The left tympanic membrane is thickened and retracted inwards. The left middle ear ossicles and scutum are intact. Normal aeration of the external auditory canals with intact bony and cartilaginous boundaries. The right middle ear cavity is normally aerated with intact ossicles. The right mastoid air cells are unremarkable.
CRIOT2018-7639784.001.jpg
PMC6207856_01_CRIOT2018-7639784.001.jpg
fig1
High-resolution computed tomography (HRCT) and magnetic resonance imaging were performed (Figures 1-4).
High-resolution CT scan (coronal cut) of the temporal bone. Total opacification of the left-sided hypo- and mesotympanum by a soft tissue density. Mastoid air cells totally opacified with resorption of septae and partially sclerosed bone. Partial dehiscence of the mastoid portion of the facial nerve canal. The left tympanic membrane is thickened and retracted inwards. The left middle ear ossicles and scutum are intact. Normal aeration of the external auditory canals with intact bony and cartilaginous boundaries. The right middle ear cavity is normally aerated with intact ossicles. The right mastoid air cells are unremarkable.
CRIOT2018-7639784.002.jpg
PMC6207856_01_CRIOT2018-7639784.002.jpg
fig2
High-resolution computed tomography (HRCT) and magnetic resonance imaging were performed (Figures 1-4).
MRI of cerebellopontine angles and posterior fossa (coronal cut). Opacification of the left mastoid air cells and middle ear cavity with soft tissue signal which elicits low signal in T1WI and high signal in T2WI with restricted diffusion in DWI. There is homogeneous enhancement following IV contrast administration. No evidence of adjacent intracranial abscess formation or sinus thrombosis. The region of brain stem and cerebellar hemispheres are normal. No focal lesions are seen. Both the VII and VIII cranial nerves show normal course and signal intensity. No intra- or extra-canalicular enhancing lesion is seen.
CRIOT2018-7639784.003.jpg
PMC6207856_01_CRIOT2018-7639784.003.jpg
fig3
High-resolution computed tomography (HRCT) and magnetic resonance imaging were performed (Figures 1-4).
MRI of cerebellopontine angles and posterior fossa (axial cut). Opacification of the left mastoid air cells and middle ear cavity with soft tissue signal which elicits low signal in T1WI and high signal in T2WI with restricted diffusion in DWI. There is homogeneous enhancement following IV contrast administration. No evidence of adjacent intracranial abscess formation or sinus thrombosis. The region of brain stem and cerebellar hemispheres are normal. No focal lesions are seen. Both the VII and VIII cranial nerves show normal course and signal intensity. No intra- or extra-canalicular enhancing lesion is seen.
CRIOT2018-7639784.004.jpg
PMC6207856_01_CRIOT2018-7639784.004.jpg
fig4
High-resolution computed tomography (HRCT) and magnetic resonance imaging were performed (Figures 1-4).
Microphotograph shows diffuse infiltration of large neoplastic lymphoid cells. HEx100x.
CRIOT2018-7639784.005.jpg
PMC6207856_01_CRIOT2018-7639784.005.jpg
fig5
Microphotograph shows atypical large lymphoid cells with prominent 1-2 nucleoli, subendothelial infiltration, frequent mitoses, and a pseudorosette. HEx200x.
CRIOT2018-7639784.006.jpg
PMC6207856_01_CRIOT2018-7639784.006.jpg
fig6
High-power view of transformed lymphoid cells and mitoses. HEx400x.
CRIOT2018-7639784.007.jpg
PMC6207856_01_CRIOT2018-7639784.007.jpg
fig7
Ki67 by immunohistochemistry shows high proliferation index (80-90%). 200x.
CRIOT2018-7639784.008.jpg
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fig8