PMC9515540_01
Chest CT. Chest CT before treatment (A). Chest MRI before treatment (B).
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Chest CT and MRI showed a size of 2.9 x 2.7-cm space occupying lesion in the left breast, mediastinum, and left hilar lymph node metastasis ( Figures 1A, B ).
Puncture pathology of left breast mass.
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MRI showed no abnormalities. Metastatic squamous cell carcinoma from cervix was considered in the pathological biopsy of left breast mass ( Figure 2 ) and left hilar ( Figure 3 ), and the immunohistochemical examination of left breast tumor cells showed ER(-), PR(-), HER-2(2+), CK5/6(+), P63(+), SMMHC(-), GTA-3(+), EGFR(+), P53(wild type), Ki67(80%+), and P16(+).
Puncture pathology of the left porta of the lung.
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MRI showed no abnormalities. Metastatic squamous cell carcinoma from cervix was considered in the pathological biopsy of left breast mass ( Figure 2 ) and left hilar ( Figure 3 ), and the immunohistochemical examination of left breast tumor cells showed ER(-), PR(-), HER-2(2+), CK5/6(+), P63(+), SMMHC(-), GTA-3(+), EGFR(+), P53(wild type), Ki67(80%+), and P16(+).
Three-dimensional dose distribution and DVH of the first fraction of IB.
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The three-dimensional dose distribution and Dose Volume Histogram (DVH) are shown in  Figures 4 ,  5 , and dose parameters are described in  Table 1 .
Three-dimensional dose distribution and DVH of the second fraction of IB.
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The three-dimensional dose distribution and Dose Volume Histogram (DVH) are shown in  Figures 4 ,  5 , and dose parameters are described in  Table 1 .
Three-dimensional dose distribution and DVH of the left porta of the lung.
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The three-dimensional dose distribution and DVH are shown in  Figure 6 , and dosimetric parameters are described in  Table 1 .
Chest CT after treatment.
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According to the RECIST standard for tumor efficacy evaluation, the left hilar metastasis reached complete remission (CR), and the left breast metastases reached partial remission (PR) ( Figure 7 ), but the patient refused to accept to continue treatment.