PMC9830185_01
PMC9830185_02
Clinical improvement of patients after 6 weeks of dupilumab treatment. (A and B) at baseline; (C and D) after 6 weeks of treatment.
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PMC9830185_02_JAA-16-1-g0001.jpg
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The first time he came to our clinic, the lesions on the palm and plantar showed not only yellowish vesicles, blisters, bullae, and even bloody bulla, swelling and scabs accompanied by intense itching and pain that made it incapacitated for the hands and feet (Figure 1A and B). At week 6, the hands and feet were completely normal without relapse (Figure 1C and (D), and after 16 weeks of treatment, there was no recurrence or adverse events at 1.5 years of discontinuation.