PMC4354615_01
Endoscopic findings.. Notes: (A) Mucosal erosion and ulceration in rectum. (B) The lesion got little improvement after 10-day course of metronidazole. (C) The lesion showed complete recovery of the ulceration.
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We performed colonoscopy, which revealed mucosal erosion and ulceration from the sigmoid colon to rectum (Figure 1A). After treatment, her symptoms persisted and we performed follow-up colonoscopy, which showed only minimally improved ulceration (Figure 1B). Two months later, we performed follow-up colonoscopy, which showed complete resolution of ulceration (Figure 1C); biopsy demonstrated no CMV-infected cells.
Histopathological findings. (A) Hematoxylin-eosin stained, 100x. (B) Immunohistochemistry for cytomegalovirus, 200x.
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Hematoxylin-eosin stained biopsy specimens of ulceration showed no inclusion bodies (Figure 2A), but immunostained specimens revealed CMV-infected cells (Figure 2B).