PMC165439_01
Disc cartilage regeneration during 2 years of supplement intake. T2-weighted MR images of lumbar spine, made in September 1999 (start of supplement intake), 2000 and 2001. Note the increase of MRI signal of disc L3-4 (thick arrows) and disappearance of focal disc protrusion (thin arrow) of this disc. Note that the fully degenerated L4-5 disc remains unchanged. Upper panels and lower panels represent two consecutive images of planes 4 mm apart.
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F1
T2-weighted MRI signal, as shown in Figure 1. The L3-4 disc showed an initial protrusion, which decreased in time, while the MRI signal normalized in time. Yet, it is unlikely that a disc recovery to an extent shown in Figure 1 would have happened spontaneously at an age of almost 60 year, and by chance concomitant with the supplement intake.