PMC8408891_01
Twelve-lead electrocardiogram (ECG) of the patient. ECG showed wide QRS complexes and peaked T waves consistent with hyperkalemia at the time of patient's admission to the hospital.
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Electrocardiogram showed widening of the QRS complex with acute T-wave changes (Figure 1) that resolved after electrolyte normalization (Figures 2 and 3).
Peaked T waves resolved after the patient's potassium normalized following treatment.
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Electrocardiogram showed widening of the QRS complex with acute T-wave changes (Figure 1) that resolved after electrolyte normalization (Figures 2 and 3).
Electrocardiogram (ECG) after resumption of alpelisib. Remains at baseline without return of acute T wave abnormalities.
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Electrocardiogram showed widening of the QRS complex with acute T-wave changes (Figure 1) that resolved after electrolyte normalization (Figures 2 and 3).
Graphic representation of trends in potassium (A), phosphate (B), creatinine (C), uric acid (D), and lactate dehydrogenase (E) during patient's hospitalization.
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Creatinine continued to downtrend and normalized to 1.00 on hospital day 6 (Table 1 and Figure 4). All other clinically significant laboratory abnormalities also resolved (Figure 4).