PMC4537719_01
Abdominal computed tomography revealed an ill-defined tumor arising from the lower pole of the right kidney.
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fig1
Upper abdominal computed tomography revealed a horseshoe kidney and a well-defined mass of 4 cm arising from the lower pole of the right kidney (Figure 1).
Gross photograph of the cut surface of the right kidney showing a heterogeneous tumor mass.
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fig2
The cut surface of the excised specimen showed a solid, circumscribed, heterogeneous tumor (size 4.3 x 3.5 cm), with solid areas alternating with cystic and hemorrhagic areas with widely clear margins (Figure 2).
(a) Tumor pseudocapsule composed of fibrous tissue. H&E stain, x50. (b) Papillae covered by large cells with abundant eosinophilic cytoplasm. H&E stain, x100. (c) Pseudostratified high-grade nuclei with prominent nucleoli. H&E stain, x400.
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Histopathological examination revealed a tumor surrounded by a pseudocapsule, composed of papillae covered with cells with abundant eosinophilic cytoplasm and high-grade nuclei with prominent nucleoli (Figure 3).
(a) Reactivity to EMA. Immunohistochemical stain with anti-EMA antibody, x100. (b) Reactivity to Vimentin. Immunohistochemical stain with anti-Vimentin antibody, x100. (c) Reactivity to AMACR. Immunohistochemical stain with anti-AMACR antibody, x100.
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fig4
EMA, Vimentin, and AMACR were strongly positive (Figure 4).