PMC5881962_01
A tender, hard, midline anterior neck mass (circle) at the level of the hyoid bone.
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On examination, he had a tender, hard midline anterior neck mass (6.0 x 4.0 x 4.0 cm) at the level of hyoid bone that elevated on swallowing (Figure 1).
(a) MRI T2-weighted sections in axial plane and (b) sagittal plane shows a lesion with mixed signals and no clear margins arising from notch thyroid and extend to midline tongue base.
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The lesion appeared to arise from notch thyroid and extend to midline tongue base (Figure 2).
The excised mass that was found to adhere to the hyoid bone and surrounding muscles.
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Grossly, the mass (6.0 x 4.0 x 4.0 cm) composed of chief solid lesion with partial cystic lesion adhering to hyoid bone and surrounding muscles (Figure 3).
(a) Histopathological image of the mass specimen demonstrating the fibrous stroma with invasive nests of atypical squamous cells (H&E, x20). Immunohistochemically, positivity for (b) CKpan, (c) 34bE12 and (d) p40 was observed in the invasive tumor nests confirming squamous cell carcinoma (x20).
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Microscopically, the mass presented numerous differentiated malignant squamous cells (Figure 4).
No regional or distant metastasis was revealed by PET scan.
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Whole body positron emission tomography (PET) scanning did not reveal any regional or distant metastatic diseases (Figure 5).