PMC8214888_01
Photomicrograph of the biopsy showed: A - biphasic tumor comprising of fibrous as well epithelial component (H&E,10X); B - epithelial component disposed mainly in a glandular pattern along with cords (H&E,20X); C - shows an area of fibrous component (H&E,20X); D - Higher magnification shows round to oval epithelial cells with bland nuclear features and mild to moderate cytoplasm, No pleomorphism (H&E,40X).
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The biopsy histomorphology showed a biphasic tumor comprising fibrous stroma with cords and glandular pattern of epithelial cells exhibiting a central discohesion (Figures 1A, 1B). Some areas show fibrous components (Figure 1C). The high-power examination showed round to oval epithelial cells with bland nuclear features and mild to moderate cytoplasm, and no pleomorphism (Figure 1D).
Photomicrographs of the IHC study on the biopsy specimen. A - CK positive; B - Mib proliferation index 20-30%; C - SMA - negative; D - S100 equivocal. (all pictures 40X).
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CK positivity, MIB proliferation index (KI 67) 20-30%, SMA-negative, S100-equivocal (Figures 2A, 2B, 2C, and 2D). CD34 was negative.
CT study of right leg: A - Sagittal sections reveal multiple patchy cortical erosions/irregularities in the right tibia centered in the diaphysis and contiguously involving the adjacent upper metaphysis. Note adjoining soft tissue thickenings. Streak artifacts are noted due to postoperative changes (Screws); B - MRI Sagittal section of right leg reveals cortical erosions/irregular outlines of the tibia with altered signals in the adjoining bone marrow and soft tissue. Susceptibility artifacts are noted due to postoperative metallic screws.
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Streak artifacts are noted due to postoperative changes (screws) (Figure 3A). Susceptibility artifacts are noted due to postoperative metallic screws (Figure 3B).