PMC8316597_01
CT images. (A) Plain scan; (B) arterial phase; and (C) portal venous phase.
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F1
Abdominal computed tomography (CT) (Figure 1) revealed marked liver enlargement and a large soft tissue mass on the right hepatic lobe with an estimated volume of 17.4 x 16.1 x 20.1 cm.
CT images after TACE. (A) Plain scan; (B) arterial phase; and (C) portal venous phase.
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F2
Tumor appearance. (Left) Operating field after excision of right, caudate and quadrate lobe of liver; (Right) gross specimen.
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F3
The resected liver tissue had a volume of 26 x 23 x 12 cm (Figure 3). The resected liver tissue had a volume of 26 x 23 x 12 cm (Figure 3).
Immunohistochemical expression. (A) HE staining; (B) Hepatocyte(+); (C) Glypican-3 (+); (D) AFP (+); (E) CgA (+); (F) SYN (+); (G) Arginase-1 (-); and (H) KI-67.
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F4
Nuclear molding change and mitoses were frequently observed (Figure 4A). Nuclear molding change and mitoses were frequently observed (Figure 4A). A small nest strongly expressed SYN on the cell membrane (Figure 4F). AFP diffusely (Figures 4C,D). And the small nest showed weak AFP expression. All small round cells showed CgA positivity (Figure 4E). Postoperative pathological findings (Figure 4) confirmed a mixed neuroendocrine-non-neuroendocrine neoplasm. Postoperative pathological findings (Figure 4) confirmed a mixed neuroendocrine-non-neuroendocrine neoplasm.