PMC3762521_01
Axial view of the ultrasound scan of the survivor's head at 20 weeks of gestation. This shows bilateral ventriculomegaly and dilatation all around the subarachnoid cavity.
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At 20 and 3/7 weeks of gestation, ultrasonography showed that the surviving twin had bilateral ventriculomegaly and all around dilatation of the subarachnoid cavity despite a normal head size and appropriate interval growth (Figure 1).
Axial view of the magnetic resonance T2-weighted image of the survivor's head at 20 weeks of gestation. Bilateral ventriculomegaly and dilatation all around the subarachnoid cavity are documented as same as ultrasonography findings. In addition, atrophy of the cerebral cortex is remarkable.
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Fetal MRI revealed remarkable atrophy of the cerebral cortex (Figure 2).
Gross appearance of the survivor's brain (left lateral view). The cerebellum and brain stem were almost normal (arrow). The cerebrum was very softened and atrophic (arrowhead).
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The pathological findings through autopsy confirmed encephalomalacia in the surviving twin (Figure 3).
Microscopic findings of the survivor's cerebral cortex. (Hematoxylin and eosin stain). Definitive cortical layers were seen. Neuron density of cerebral cortex was remarkable decreased and migrating neurons were almost absent.
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Definitive cortical layers were seen but almost injured (Figure 4).