PMC8552574_01
Necrotic lesions on the right pretibial region.
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F1
In the right pretibial region there were confluent lesions in necrotic areas (figure 1).
Histologic findings: leukocytoclastic vasculitis with perivascular inflammatory infiltrate, endoluminal thrombosis and thickening of the blood vessels wall.
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F2
There were also endoluminal thrombosis and thickening of the blood vessels wall (figure 2).
Necrotic hemorrhagic evolution of the lesions of lower limbs.
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F3
Nevertheless, the patient gradually worsened with necrotic hemorrhagic evolution of the lesions of lower limbs (figure 3) and new onset of erythematous macules on the wrists and forearms.
Improvement of the skin lesions after a single infusion of IVIg (2 g/kg).
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F4