PMC9743192_01
Urticarial and palpable non-blanching purpuric rash compatible with mild mixed perivascular infiltration of lymphocytes and neutrophils in the superficial dermis, oedema of blood vessels endothelium, no vessels wall necrosis identified.
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On the initial physical examination, next to typical urticaria on the limbs and trunk, some palpable non-blanching purpuric papules were noticed on the thighs (Figure 1). Histopathologic findings revealed mild mixed perivascular infiltration of lymphocytes and neutrophils in the superficial dermis, a thin interstitial neutrophil infiltrate of the derma, oedema of the vascular endothelium, and vessel wall necrosis, but no signs of IgA vasculitis were found (Figure 1).
PMC9743192_02
A palpable non-blanching purpuric rash on the right thigh and a sore with necrosis signs on the right shin.
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On physical examination, a palpable non-blanching purpuric rash on all extremities (Figure 2) was evident with some small sores with necrosis on the right shin (Figure 2).
Small vessels oedema of endothelium with perivascular leukocytoclasis, erythrocytes extravasation with focal IgA deposition in the vessels.
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IgA deposition in the vessels (Figure 3). IgA vasculitis (Henoch-Schonlein purpura) was diagnosed.