PMC8826680_01
Chest radiography on admission.
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F1
A chest-X ray was performed, revealing diffuse heterogeneous bilateral infiltrates (Figure 1).
(A) Ventilatory support diagram. CMV, conventional mechanical ventilation; HFOV, high flow oscillatory ventilation; iNO, inhaled nitric oxide; NMB, neuromuscular blockade. (B) Anti-infectious treatment diagram. TMS-SMX, trimethoprim-sulfamethoxazole; PMT + SDZ, pyrimethamine + sulphadiazine.
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F2
FiO2 100%. Figure 2A shows the evolution of respiratory support. Treatment with pyrimethamine, sulphadiazine and folinic acid was started, and as subsequent microbiological tests were negative, the other antimicrobial therapies were progressively withdrawn (Figure 2B).
Summary of blood analytical values during PICU stay. CRP, C reactive protein; WBC, white blood cell; PICU, pediatric intensive care unit.
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F3
Evolution of blood test values during PICU stay is shown in Figure 3.