PMC5633661_01
Mineralization nodules are protruding from the sub-pleura (arrow heads). The right lung shows a large secondary tumor growth (arrow).
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F1
Those located superficially are protruding irregular grayish white stony masses of 1.0-5.0 mm in diameter with occasional boney spicules that perforate the pleura (Fig. 1 and 2).
Large irregular prominent white boney particles are seen through the lung surface (Arrows). Some boney spicules perforate to the lung surface through the pleura (Inset). Dark spots are Carbon particles.
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F2
Those located superficially are protruding irregular grayish white stony masses of 1.0-5.0 mm in diameter with occasional boney spicules that perforate the pleura (Fig. 1 and 2).
Multiobular intra-alveolar mass of boney structure are seen. Part of the metastatic tumor is seen in the left upper corner. The lung is rather emphysematous (Magnification: X40).
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F3
Alveoli distended with such structures had their walls usually stretched or ruptured (Fig. 3 and 4).
Ossification lobules showing lamellated orientation with osteocytes in lacunae. They are surrounded by stretched alveolar wall membrane (Magnification: X100).
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F4
Alveoli distended with such structures had their walls usually stretched or ruptured (Fig. 3 and 4).
Intra-alveolar onion-like concretion formed of strongly basophilic non-cellular lamination which encloses a faintly eosinophilic soft substance (Magnification: X400).
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F5
These are solitary measuring about 30 um and are formed of non- cellular deeply basophilic onion-like laminations which may enclose faint eosinophilic soft substance (Fig. 5).