PMC3271838_01
Blue nodules a on the palm of the hand, b on the elbow, and c on the foot.
CDE-0004-0001-g01.jpg
PMC3271838_02_CDE-0004-0001-g01.jpg
F1
Her younger sister, aged 6 years old, was noted to have similar lesions on her feet (fig.1c).
PMC3271838_02
Blue nodules a on the palm of the hand, b on the elbow, and c on the foot.
CDE-0004-0001-g01.jpg
PMC3271838_02_CDE-0004-0001-g01.jpg
F1
Her younger sister, aged 6 years old, was noted to have similar lesions on her feet (fig.1c).
aIntradermal thin-walled folded and dilated vascular channels (haematoxylin and eosin, original magnification x50). b Intradermal vascular channels lined by benign flat endothelial cells and monomorphic round glomus-like cells with large nuclei and slightly eosinophilc cytoplasm (haematoxylin and eosin, original magnification x350).
CDE-0004-0001-g02.jpg
PMC3271838_02_CDE-0004-0001-g02.jpg
F2
These were surrounded by irregular layers of cuboidal cells, in keeping with glomus-like cells (fig.2a, b), which stained positively for smooth muscle actin on immunohistochemistry (fig.2c).