PMC5985547_01
Magnetic resonance imaging of the lumbar spine performed without the administration of intravenous contrast demonstrating septic discitis at the L4-L5 interspace along with epidural abscesses extending from L3 to L5 and S1 to S2.
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Furthermore, magnetic resonance imaging (MRI) of the lumbar spine demonstrated septic discitis at the L4-L5 interspace along with epidural abscesses extending from L3 to L5 and S1 to S2 (see Figure 1).
Light microscopy of a renal biopsy demonstrating diffuse global hypercellularity with mesangial and endocapillary proliferation as well as infiltrating monocytes and occasional neutrophils.
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There was diffuse global hypercellularity with mesangial and endocapillary proliferation as well as infiltrating monocytes and occasional neutrophils, consistent with proliferative glomerulonephritis (see Figure 2).
Immunofluorescence of a renal biopsy demonstrating diffuse granular staining for C3 (left) and IgA (right) in the glomerular basement membrane and mesangium.
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There was trace staining for IgG, lambda, and kappa and negative staining for IgM and C1q (see Figure 3).
Electron microscopy of a renal biopsy demonstrating a large subepithelial deposit with a hump-like appearance as well as some mesangial and paramesangial electron dense deposits.
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HSP, prompting the initiation of prednisone at a dose of 1 mg/kg daily. However, electron microscopy performed the following day demonstrated large subepithelial deposits with a hump-like appearance (see Figure 4).