PMC7481371_01
The positron emission tomography-computed tomography (PET-CT) scan at the first admission and the end of the salvage treatment. (A) The PET-CT scan at the first admission revealed elevated FDG uptake in multiple enlarged lymph nodes in the bilateral parotid gland, bilateral cervical, bilateral axillary, mediastinal, retroperitoneal, bilateral pelvic, bilateral inguinal regions, and in the nasopharynx, tonsil and spleen (arrow). (B) The PET-CT scan showed no elevated FDG uptake lesions at the end of the salvage treatment.
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F1
A further 18FDG positron emission tomography-computed tomography (PET-CT) scan confirmed that multiple FDG-avid enlarged lymph nodes in the bilateral cervical, bilateral axillary, mediastinal, retroperitoneal, bilateral pelvic, and bilateral inguinal regions (Figure 1A). The response was complete remission at the end of the salvage treatment, which was confirmed by the PET-CT scan (Figure 1B).
The positron emission tomography-computed tomography (PET-CT) scan at the time of relapse. The PET-CT scan showed elevated FDG uptake in the retroperitoneal and bilateral pelvic regions, (arrow).
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The further 18FDG PET-CT scan confirmed that multiple FDG-avid enlarged lymph nodes in the retroperitoneal and bilateral pelvic regions (Figure 2).
The clinical course of the treatment for relapsed/refractory angioimmunoblastic T cell lymphoma (AITL) with Evans syndrome. The clinical course from the occurrence of Evans syndrome to recovery. The continuous laboratory findings showed that anemia worsened quickly at the first stage, and the lowest number of Hb was 46 g/L. The main treatment was the transfusion of the washed red blood cells. The thrombocytopenia occurred 15 days later, and the lowest number of platelets was 15 x 109/L. Refractory/relapsed AITL combined with secondary Evans syndrome was diagnosed at the second stage. The patient received the first-line treatments for Evans syndrome including prednisone and intravenous immunoglobulin. However, anemia and thrombocytopenia did not improve significantly. The combination of chidamide and cyclosporine were administrated at the third stage, and the anemia and thrombocytopenia gradually improved.
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The anemia and thrombocytopenia gradually improved after oral chidamide and cyclosporine, which was shown in Figure 3.