PMC3804584_01
The changes in glucose metabolism using FDG-PET before and after selegiline treatment.. Notes: (A) Before selegiline treatment, the patient's 17-item HDRS score was 19 points; (B) after 20 weeks of selegiline treatment, a 17-item HDRS score was 4 points. Selegiline treatment increased glucose metabolism in the bilateral basal ganglia (red arrows) and decreased glucose metabolism in the occipital lobe (white arrows).. Abbreviations: FDG-PET, [18F]-fluorodeoxyglucose positron emission tomography; HDRS, Hamilton Depression Rating Scale; MRI, magnetic resonance imaging.
ndt-9-1591Fig1.jpg
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f1-ndt-9-1591
Twenty weeks after selegiline treatment, selegiline-induced enhancement of glucose metabolism was observed in the bilateral basal ganglia by FDG-PET, while decreases were shown in those in the occipital lobe (Figure 1).