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Clinical photograph of skin metastasis
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Then, he presented to AIIMS Jodhpur, Urology department in 2022 with complaints of hematuria on and off for 5 days and decreased urine output with few violaceous nontender nodules present over the right groin region for the past 20 days [Figure 1].
(a) Photomicrograph of skin nodule showing tumor cells arranged in a nesting pattern (H and E, x40), with occasional germinal center is identified. (b) High-power view shows the glandular architecture of the tumor with individual tumor cells having hyperchromatic nuclei and eosinophilic to clear cytoplasm (H and E, x400). (c) The tumor cells showed diffuse cytoplasmic immunopositivity for PSA (IHC, x100). H and E: Hematoxylin and eosin, IHC: Immunohistochemistry, PSA: Prostate-specific antigen
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On follow-up, the skin lesion turned out to be metastatic deposits, and on immunohistochemistry testing, the lesions were positive for PSA [Figure 2].