PMC9727639_01
caecal circumscribed ulceration with central small polypoid lesion. No signs of active bleeding and remaining segments of the colon were normal.
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The remaining segments of the colon were normal as shown in Fig. 1.
A, B (Coronal and axial cross sectional images of the abdomen, respectively) demonstrating evidence of a large ill-defined, eccentrically placed, heterogeneously enhancing soft tissue mass occupying the cecum. The mass extending across the serosal surface with multi-lobulated extra luminal component having broad area of contact with anterior peritoneum. C, D (Coronal and axial cross sectional images of the abdomen, respectively) shows near-total interval resolution of previously visualized exophytic caecal mass. There is significant interval resolution of previously visualized ill-defined eccentric heterogeneously enhancing soft tissue caecal wall thickening.
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Fig. 2A, B. Follow up CT (Fig. 2 C, D) showed near-total interval resolution of previously visualized exophytic caecal mass as well as significant interval resolution of previously visualized ill-defined eccentric heterogeneously enhancing soft tissue caecal wall thickening.
(A) Several trophozites of amoeba (arrows) are present within hemorrhagic necroinflammatory debris. They contain ingested red blood cells (insets). (B) PAS stains the amoeba trophozoites magenta (arrow heads) PAS: Periodic acid-Schiff.
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Several trophozoites of amoeba -were highlighted by PAS stain- within necrosis shown in Fig. 3.
(A) The inflammation in the non-ulcerated fragments had decreased. (B) With the regeneration of crypts, there is some mild architectural distortion. (C) Sloughed surface epithelium (arrows) with deposition of fibrinopurulent exudate (arrow heads) and underlying granulation tissue are shown in this picture of a persistent ulcer. There is no evidence of an amoeba.
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The follow up histopathology report (Fig. 4) showed no residual amoeba histolytica trophozoites and unremarkable for any other pathogens.