PMC3469180_01
Sparganosis. Ultrasonography shows a serpiginous hypoechoic structure and this compartment is surrounded by a hyperechoic area
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On ultrasonography, a hypoechogenic structure, measuring 2.0cmx2.0cm in size adjacent to a hyperechogenic area was observed (Fig. 1).
Sparganum removed from the lesion in the patient's thigh
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A long, slender, whitish, non-vermigrade worm, approximately 10 cm in length and 5 mm in width was removed (Fig. 2).
Cross section of sparganum. Many calcareous corpuscles were observed in the cavity (arrows) (H&E x 100)
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The parenchyma was composed of parechymal cells, calcareous corpuscles, excretory ducts and muscle fibers (Fig. 3).
The plerocercoid was surrounded by fibrous tissue and mixed inflammatory cell infiltrates, including lymphocytes and eosinophils. (H&E, x100 and x400 [inset])
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The worm was surrounded by fibrous tissue, lymphocytes, and eosinophils (Fig. 4).
(a) The results of a multiple-dot enzyme-linked immunosorbent assay (ELISA) for the diagnosis of parasitic disease. (b) Anti-sparganum mansoni IgG antibody titers measured by microplate ELISA. Antibody titers are expressed as the optical density (O.D.) at 405 nm. A value of 0.1 or less was considered nonspecific
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Because her serum was positive for S. mansoni in this assay (Fig. 5a), we tested for parasite-specific IgG antibody using a microplate ELISA for further investigation. The result clearly showed that her parasite-specific IgG antibody titer was high (Fig. 5b). The serum titer of the parasite-specific IgG antibody had decreased significantly (Fig. 5b).