PMC2820021_01
Clinical presentation of innumerable seborrheic keratoses concentrated over the face, neck, back, and chest.
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F1
On admission, dermatologic examination noted florid eruption of innumerable keratotic lesions of the face, neck and thorax, ranging in size from 3 to 15 mm (Figure 1).
(a) Histopathologic features and (b) immunohistochemical expression of EGFR in specimen from back lesion showing intense membranous staining of EGFR in the basal keratinocytes and throughout the upper epidermal layer.
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PMC2820021_01_1756-8722-3-2-2.jpg
F2
Histopathological examination of a surgical skin biopsy confirmed the clinical diagnosis of seborrheic keratosis and was used for EGFR immunohistochemical analysis (Figure 2).