PMC7717959_01
Cardiac magnetic resonance imaging included cine MRI (left column), native T1 mapping (middle column), and late gadolinium enhancement (LGE) imaging (right column) and demonstrated several myocardial metastases on the two-chamber views (green arrows) and three metastases in the four-chamber views (cyan arrows). The metastases were best seen on T1 mapping and cine MRI and had long T1 and T2 (not shown) relative to myocardium.
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Echocardiogram and cardiac magnetic resonance imaging confirmed the presence of at least 7 distinct myocardial lesions of the left atrium and left ventricle, ranging from 0.65 cm x 0.65 cm to 2.0 cm x 1.6 cm, with preservation of the left ventricular ejection fraction (Figure 1).
Axial and sagittal sections of CT scans depicting sacral chordoma (asterisk) with left inguinal lymphadenopathy (arrow) prior to brachyury vaccine (A, D), 4 weeks after the first dose of vaccine (B, E), and 16 weeks after the first dose of vaccine (C, F). Imaging demonstrates stable disease by response evaluation criteria in solid tumors (RECIST) criteria, with 1.54 and 3.38% changes in baseline at 4 weeks (B, E) and 16 weeks (C, F), respectively.
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Restaging CT scans at that time demonstrated stable disease (Figure 2).