PMC9898768_01
penile necrosis (arrow)
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F1
Patient information: a 52-year-old male presented to our hospital for the gradual development (for three weeks) of a very painful necrotic lesion involving the whole penis (Figure 1).
bedsore of the left heel with Charcot's neuro-osteoarthropathy (arrow)
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F2
Clinical finding: the general examination revealed a febrile (temperature: 38.5 C), asthenic, anxious patient with necrotic bedsore on the left heel (Figure 2).
A) postoperative total penectomy; B) macroscopic aspect of the surgical specimen after formalin fixation
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F3
Intraoperatively, the total penile shaft was found to be completely necrotic, with greater than 75% of the penile corpora filled with pus, for which a total penectomy and excision of the left heel necrotic bedsore were performed (Figure 3).
histological aspect of the excised part: A) micrograph (Gx20 - HE staining) showing the penile parenchyma totally remodeled by suppurative necrosis sites; B): micrograph (Gx20 - HE staining) showing extensive calcic deposits within totally ischemic and phantom areas
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F4
The histopathological examination revealed numerous foci of microcalcifications as well as extensive ischemic and necrotic remodeling on the entire penile parenchyma consistent with calciphylaxis (Figure 4).