PMC5903131_01
PMC5903131_02
Assessment and plan of the treating radiologist from 1962.
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F1
However, careful radiation therapy cannot do any harm and probably may do some good" (Fig. 1).
T1-weighted brain MRI with contrast at the time of diagnosis of radiation-induced glioblastoma multiforme.
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F2
A contrast-enhanced brain MRI demonstrated a 3 x 3 cm right frontoparietal resection cavity surrounded by a 5 x 4 cm area of heterogeneous contrast enhancement extending to the right corona radiata and periventricular white matter with associated cerebral edema (Fig. 2).
Radiation-induced glioblastoma multiforme demonstrating increased cellularity with marked nuclear atypia, necrosis, and vascular endothelialization.
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F3
The mass was not technically resectable due to location and biopsy was consistent with GBM, wild-type isocitrate dehydrogenase and unmethylated O6-methylguanine DNA methyltransferase (MGMT), with an MIB-1 index of 50% (Fig. 3).