PMC535548_01
Pleural fluid at 630x demonstrating small round cells with salt and pepper chromatin. Note multiple mitotic figures
1742-6413-1-5-1.jpg
PMC535548_01_1742-6413-1-5-1.jpg
F1
The fluid was grossly bloody and cytology revealed abundant, round, basophilic single cells, many in mitosis, with characteristic granular, "salt and pepper" nuclear chromatin (Figure 1).
Cell block stained with CK20 demonstrating sharp perinuclear dot like pattern.
1742-6413-1-5-2.jpg
PMC535548_01_1742-6413-1-5-2.jpg
F2
A cellblock was made and immunohistochemical staining with CK20 revealed characteristic positivity in a dot like rim pattern (Figures 2).