PMC2632615_01
Computed tomography scan of the cervical neck.
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F1
Chest X-ray showed enlargement of the superior mediastinum, deviation of the trachea to the left and bilateral pulmonary metastatic lesions. Computed tomography scan of the neck, thorax and abdomen revealed enlargement of the left thyroid lobe extending to the anterior mediastinum and compressing the trachea, metastatic bilateral pulmonary lesions and a large, nodular, contrast-enhanced mass-occupying lesion in the right hepatic lobe (figures 1, 2, 3).
Computed tomography scan of the thorax.
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F2
Chest X-ray showed enlargement of the superior mediastinum, deviation of the trachea to the left and bilateral pulmonary metastatic lesions. Computed tomography scan of the neck, thorax and abdomen revealed enlargement of the left thyroid lobe extending to the anterior mediastinum and compressing the trachea, metastatic bilateral pulmonary lesions and a large, nodular, contrast-enhanced mass-occupying lesion in the right hepatic lobe (figures 1, 2, 3).
Computed tomography scan of the liver.
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F3
Chest X-ray showed enlargement of the superior mediastinum, deviation of the trachea to the left and bilateral pulmonary metastatic lesions. Computed tomography scan of the neck, thorax and abdomen revealed enlargement of the left thyroid lobe extending to the anterior mediastinum and compressing the trachea, metastatic bilateral pulmonary lesions and a large, nodular, contrast-enhanced mass-occupying lesion in the right hepatic lobe (figures 1, 2, 3).
Fine-needle aspiration biopsy smear of the thyroid (Papanicolaou stain).
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F4
These cells were isolated and in tissue fragments with large irregular nuclei, which showed clumped chromatin with parachromatin clearing and occasional large, multiple and irregular nucleoli (figure 4).
Liver biopsy stained with thyroglobulin.
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F5
Moreover, immunocytochemical staining revealed that a small number of these anaplastic cells were slightly positive for thyroglobulin (figure 5).