PMC10344635_01
Invasive ductal carcinoma (IDC), moderately-differentiated ((a) x100). Ductal carcinoma in situ (DCIS), intermediated nuclear grade, cribriform type ((b) x100). Lobular carcinoma in situ (LCIS), classic type ((c) x100). Metastatic carcinoma in the lymph node, arrow indicating focus of metastatic carcinoma ((d) x100).
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fig1
The patient underwent right mastectomy with axillary sentinel lymph node dissection in September 2015, and the final pathology showed invasive ductal carcinoma, moderately-differentiated (grade 2) (Figure 1(a)), with solid papillary features and necrosis, measuring 3.5 cm in the greatest dimension, with clear surgical margins. It was associated with ductal carcinoma in situ (DCIS) (Figure 1(b)) and lobular carcinoma in situ (LCIS) (Figure 1(c)). One of two right axillary sentinel lymph nodes was positive for micrometastatic carcinoma (Figure 1(d)).
The peripheral blood showed medium-sized cells that have scanty cytoplasm, fine chromatin, and small nucleoli, resembling lymphoid blasts ((a) and (b), x400).
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fig2
The peripheral blood smear showed the atypical lymphoid cells to be medium-sized, and with scanty cytoplasm, fine chromatin, and small nucleoli, resembling lymphoid blasts (Figures 2(a) and 2(b)).