PMC6311830_01
Hematoxylin and eosin stain at 20x magnification showing a markedly hypoplastic, near aplastic bone marrow.
CRIHEM2018-9249506.001.jpg
PMC6311830_01_CRIHEM2018-9249506.001.jpg
fig1
Bone marrow biopsy/aspirate showed features consistent with severe aplastic anemia (few pockets of trilineage hematopoiesis accounting for about 2% of total cellularity and 98% fat) (Figures 1-3).
Hematoxylin and eosin stain at 100x magnification showing most of the bone marrow showing aplasia with absence of marrow elements.
CRIHEM2018-9249506.002.jpg
PMC6311830_01_CRIHEM2018-9249506.002.jpg
fig2
Bone marrow biopsy/aspirate showed features consistent with severe aplastic anemia (few pockets of trilineage hematopoiesis accounting for about 2% of total cellularity and 98% fat) (Figures 1-3).
Hematoxylin and eosin stain at 400x magnification of a rare focus showing residual trilineage hematopoiesis, in an otherwise near aplastic bone marrow.
CRIHEM2018-9249506.003.jpg
PMC6311830_01_CRIHEM2018-9249506.003.jpg
fig3
Bone marrow biopsy/aspirate showed features consistent with severe aplastic anemia (few pockets of trilineage hematopoiesis accounting for about 2% of total cellularity and 98% fat) (Figures 1-3).