PMC9547605_01
Chest CT findings of Severe Chlamydia psittaci pneumonia. (A-C) March 2, 2022: The day of admission. Large exudative foci in the right lung and a large consolidation shadow in the right lower lung. (D-F) Thirteen day after admission on March 15, 2022. Exudative foci and consolidation shadow in the right lung were less pronounced than those before. (G-I) Twenty-two day after admission on March 24, 2022. Further resorption of the right lung lesion than before. (J-L) April 24, 2022: 1 month after discharge. The lung lesions were largely resorbed, leaving only a small number of fibrous linear opacities.
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Chest CT at the time of admission (Figure 1A-C) showed multiple patchy exudative opacities in the right lung and a large consolidated shadow in the right lower lung. Chest CT re-examination indicated significant resorption of the right lung lesion (Figure 1D-F). On March 23 (day 22), chest CT re-examination indicated further resorption of the right lung lesion (Figure 1G-I), and the patient was discharged the following day. Outpatient follow-up at 1 month after discharge indicated no significant abnormalities in inflammation indices (hs-CRP and PCT) and liver and kidney functions, and chest CT indicated that the lung lesions were largely resorbed, leaving only a small number of fibrous linear opacities (Figure 1J-L).
Body temperature and antimicrobial treatment during hospitalisation with meropenem at 1.0 g ivgtt Q8h (days 1-3), moxifloxacin at 0.4 g ivgtt Qd (days 1-3), oseltamivir at 75 mg po Q12h (days 1-3), and omadacycline at 100 mg ivgtt Q12 h (day 3), 100 mg ivgtt Qd (days 4-14), and 300 mg po Qd (days 15-23).
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After 72 h of treatment, the patient's temperature gradually decreased to a normal level (Figure 2), and a complete blood count re-examination on March 7 (day 6) showed the following: WBC: 6.3 x 109/L, neutrophil percentage: 85.1%, lymphocyte count: 0.64 x 109/L, haemoglobin: 85 g/L, platelets: 116 x 109/L, hs-CRP: 127.14 mg/L, PCT: 5.53 ng, ALT: 228 U/L, AST: 430 U/L, serum creatinine: 202 micromol/L.
Change in white blood cell count and neutrophil predominance during hospitalisation.
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The patient's condition gradually improved; inflammation indices decreased significantly; and liver enzymes, creatinine, CK, and LDH gradually returned to normal levels (Figures 3-7).
Change in C-reactive protein and procalcitonin during hospitalisation.
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The patient's condition gradually improved; inflammation indices decreased significantly; and liver enzymes, creatinine, CK, and LDH gradually returned to normal levels (Figures 3-7).
Change in alanine aminotransferase and serum creatinine during hospitalisation.
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The patient's condition gradually improved; inflammation indices decreased significantly; and liver enzymes, creatinine, CK, and LDH gradually returned to normal levels (Figures 3-7).
Change in creatine kinase and lactate dehydrogenase during hospitalisation.
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The patient's condition gradually improved; inflammation indices decreased significantly; and liver enzymes, creatinine, CK, and LDH gradually returned to normal levels (Figures 3-7).
Change in the oxygenation index during hospitalisation.
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The patient's condition gradually improved; inflammation indices decreased significantly; and liver enzymes, creatinine, CK, and LDH gradually returned to normal levels (Figures 3-7).