PMC4898227_01
57-year-old female with breast calcifications. MLO images from the patient's screening mammogram demonstrate regions of abnormal-appearing calcifications in the left breast. Note the dialysis catheter over the right breast.
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When this mammogram was compared to the previous ones, it was clear that there had been interval development of several regions of heterogeneous macrocalcifications and microcalcifications in the left breast (Figure 1A, Figure 1B, Figure 1C).
57-year-old female with breast calcifications. CC images from the patient's screening mammogram demonstrate regions of abnormal-appearing calcifications in the left breast. Note the dialysis catheter over the right breast.
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The patient was called back for additional mammographic views of the left breast, which included spot magnification views in the craniocaudal (CC) and mediolateral (ML) projections, in order to further characterize the calcifications (Fig. 2).
57-year-old female with breast calcifications. Left breast CC (left) and MLO (right) images from the patient's prior screening mammogram demonstrate no abnormal calcifications.
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Eight 11-gauge core-biopsy samples were submitted to pathology for interpretation (Fig. 3).
57-year-old female with breast calcifications. Left breast spot magnification CC (left) and spot magnification ML (right) images from the patient's diagnostic mammogram demonstrate the reticular appearance of the calcifications.
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More specifically, the samples demonstrated nonuniform adipocytes, fibrosis, large lipid vacuoles, and calcifications (Fig. 4), a pattern typical of fat necrosis.