PMC9453833_01
Imaging findings of the patient. (A) and (B): the chest CT showed a 6.4 cm x 5.2 cm mass at the right hilar; (C) and (D): T1 and T2 weighted head MRI images showed the preauricular mass located at the parotid gland; (E) and (F): T1 and T2 weighted head MRI images revealed the brain metastases.
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Based on the five-year history of heavy smoking, he was arranged for a chest computed tomography (CT), which found a 6.4 cm x 5.2 cm mass at the right hilum ( Figures 1A, B ), suggesting central lung cancer. Further head magnetic resonance imaging (MRI) showed a preauricular mass located at the parotid gland ( Figures 1C, D ). Additionally, head MRI and abdominal CT showed that the head and the right adrenal were also affected ( Figures 1E, F ).
Cytological findings of parotid mass biopsy. Hematoxylin and eosin staining of the fine-needle aspiration biopsy of the preauricular mass revealed a large number of oat-shaped heteromorphic cells with deep nuclear staining at high magnification, distributed in the shape of chrysanthemum nests. The magnification was as follows respectively: (A) was 100x magnification; (B) and (C) were 200x magnification; (D) was 400x magnification.
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Hematoxylin and eosin staining of biopsy of the preauricular mass revealed a large number of oat-shaped heteromorphic cells with deep nuclear staining at high magnification, suggesting metastasis of SCLC ( Figures 2A-D ).
PMC9453833_02