PMC9030344_01
Ultrasonography abdomen done at right hypochondrium in the transverse plane (a), and epigastrium in sagittal/longitudinal plane (b) showing a heterogeneously hypoechoic intraluminal mass in the stomach (curved arrow), intraluminal air/fluid (arrow), and infiltration in the liver parenchyma (arrowhead)
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F1
On USG [Figure 1 and Video 1], a large heterogeneously hypoechoic exophytic mass was seen filling the lumen of the stomach with no obvious vascularity on Doppler.
Upper gastrointestinal barium study in anteroposterior erect (a), right posterior oblique (b), and left posterior oblique (c) view showing a filling defect in the lower esophagus (solid white arrow) and upper stomach (solid black arrow). Note the normal-appearing barium column between two filling defects
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F2
On the oral barium examination (barium swallow and meal) Figure 2, a filling defect was seen in the lower esophagus at the 8th and 9th thoracic vertebrae levels.
Axial contrast-enhanced computed tomography at the level of the lower esophagus (a), the stomach (b and c), and coronal contrast-enhanced computed tomography (d) showing heterogeneously enhancing esophageal (arrow) and gastric mass lesion (curved arrow) with adjacent liver infiltration (arrowhead)
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F3
For further imaging workup, contrast-enhanced computed tomography (CECT) of the abdomen and thorax was performed [Figure 3].
Upper gastrointestinal endoscopy images showing ulcero-proliferative growth involving distal esophagus (a) and proximal as well as mid gastric body (b)
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F4
On upper GI endoscopy [Figure 4], a small proliferative growth was seen in the lower esophagus (D8-9 level) with luminal narrowing, and the scope was negotiable.
Histopathology examinations showing squamous epithelium of esophagus with neoplastic tissue (H and E, x4 [a]), necrosis [H and E, x10 [b]), polygonal cells with vesicular chromatin, and occasional nucleoli [H and E, x40 [c])]. AB-PAS stain (d) showing no intracellular mucin
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F5
Histopathological examination [Figure 5] showed an infiltrating tumor of squamous origin with large polygonal cells in sheets and nests from both the lesions.