PMC8085679_01
Clinical aspects of small oral leucoplakia located on the tongue's left lateral border.
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Oral examination identified a sessile white plaque, of small size (measuring about 2 x 2 mm), with a smooth surface and well-defined limits, firm palpation, painless, and located on the tongue's left lateral border (Figure 1).
Features microscopic with a stratified and keratinized pavement epithelium, with cellular atypia, and tissue architecture alteration (haematoxylin and eosin stain, original magnification x100).
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Histopathological examination of a specimen stained with haematoxylin and eosin revealed a fragment of the oral mucosa coated with a stratified and keratinized pavement epithelium, with cellular atypia, and tissue architecture alteration (Figure 2).
Alterations cytological with the presence of hyperchromatism and nuclear pleomorphism (haematoxylin and eosin stain, original magnification x200).
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Among the cellular alterations, the report revealed the presence of hyperchromatism and nuclear pleomorphism (Figure 3).
Alterations in architecture with the drop projection of epithelial tissue (black arrows) (haematoxylin and eosin stain, original magnification x200).
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Additionally, an area compatible with the drop projection of epithelial tissue was observed (Figure 4).