PMC4323392_01
Clinical findings of ancient schwannoma. An indolent, hard but elastic, immovable skin tumor of 30 x 25 mm is present on the palmar aspect of the distal phalanx of the left thumb.
gox-3-e288-g001.jpg
PMC4323392_01_gox-3-e288-g001.jpg
F1
Initial examination revealed a hard but elastic, immovable tumor of 30 x 25 mm on the palmar aspect of the distal phalanx of the left thumb, with an ulcer formed at the center (Fig. 1).
Multidetector computed tomography findings. The tumor shows poor vascularization but no adherence to the surrounding bone.
gox-3-e288-g002.jpg
PMC4323392_01_gox-3-e288-g002.jpg
F2
Multidetector computed tomography (CT) of the tumor showed poor vascularization and no adhesion to the distal phalanx of thumb or articular cavity (Fig. 2).
Low-magnification image of tumor tissue section stained with hematoxylin and eosin showing a fibrous tumor capsule, growth of tightly organized spindle-shaped cells. In the tumor, the formation of cysts with internal hemorrhage is apparent. Scale bar = 5 mm.
gox-3-e288-g003.jpg
PMC4323392_01_gox-3-e288-g003.jpg
F3
The tumor also contained many various sized cysts and showed histological degenerative changes not observed in ordinary schwannoma, such as hemorrhage and prominent blood vessels with hyalinized walls (Figs. 3, 4).
High-power field image with hematoxylin and eosin stain showing newly formed blood vessels of different sizes (arrows) with hyalinization of the walls in the Antoni B region. Many cysts are scattered throughout the tumor (arrowheads). Scale bar = 150 mum.
gox-3-e288-g004.jpg
PMC4323392_01_gox-3-e288-g004.jpg
F4
The tumor also contained many various sized cysts and showed histological degenerative changes not observed in ordinary schwannoma, such as hemorrhage and prominent blood vessels with hyalinized walls (Figs. 3, 4).