PMC6344196_01
Surgical specimen. The operative specimen showed that the tumor invaded the dentate line upward and invaded the perianal skin downward. The tumor is an irregular, ulcerative type with a size of about 2*2 cm. However, according to this specimen, it is still difficult to identify the derivation of the tumor.
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F1
The surgical specimen (Fig. 1) showed the gross shape and location of the tumor.
Histopathological evaluation revealed a poorly differentiated adenocarcinoma of the anal canal. What's more, the cancer cells were small tubular or strip like, disorderly distributed, without secreted mucus in the cytoplasm, and invading the muscular layer of the anal canal. (HE.x20). HE = hematoxylin-eosin.
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F2
Histopathological evaluation of the surgical sample revealed a poorly differentiated adenocarcinoma of the anal canal (Fig. 2).
The glands are positive for CK7.(IHC.x20). IHC = immunohistochemistry.
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F3
Immunohistochemical staining showed CK7 positivity (Fig. 3).