PMC8442480_01
Overtime changes in HbA1c (black dots) and number of infection-related
hospitalizations (each event-one black cross) of the girl with 18q
deletion syndrome and type 1 diabetes. The vertical arrow denotes the
time of SIVG commencement. For reference, historical age-appropriate
HbA1c ranges for Polish population with T1D are presented
(lines-medians, boxes-25-75%). Each range was calculated based on the
sample of N children, as denoted in the bottom of the
graph. The data were collected in a cross-sectional fashion from a
majority of Polish reference centers for childhood diabetes in 2018 and
covered ~8% of total Polish pediatric population with T1D.
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PMC8442480_01_10.1177_20587384211039400-fig1.jpg
fig1-20587384211039400
Moreover, we noticed a decrease in the number of infections (from 12 annually to one in the past year) and the improvement of metabolic control of diabetes (lowering of HbA1c level) (Figure 1).