PMC9428836_01
Patient clinical course while being treated for CMV in CSF. A) Medications used to treat CMV in CSF, which included ganciclovir, foscarnet, and IT Cytogam. The color of ganciclovir corresponds to the dose: light green (10 mg/kg/day), dark green (15 mg/kg/day), orange (5 mg/kg/day), yellow (2.5 mg/kg/day), and gray (1.25 mg/kg/day). B) The patient's serum creatinine (mumol/L), which worsened with continued antiviral treatment. C) CMV PCR of CSF (in copies/mL).
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Throughout this period, from D+ 230 until D+ 382, CMV PCR in the patient's blood was checked at least once weekly and remained negative (Fig. 1).