PMC9996711_01
Prenatal fetal MR: T2-weighted images in the axial (A), coronal (B), and
sagittal (C) planes demonstrate a small focal T2 hyperintense signal (white
arrows), which extends from the skull base to the nasopharynx, consistent
with the cephalocele. Agenesis of the corpus callosum is also present
(B).
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Twin B (Figure 1).
Postnatal MR: sagittal T2 image (A) and sagittal T1 MPRAGE (B) show a large
defect consistent with a craniopharyngeal canal, with herniation of the
adenohypophysis into the defect, which protrudes into the nasopharynx (blue
arrows). Bilateral optic disc anomalies (C, white arrows) and agenesis of
the corpus callosum (D) are also present.
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AgCC, a large defect along the inferior sella turcica, consistent with the craniopharyngeal canal, with herniation of the adenohypophysis into a cephalocele protruding into the nasopharynx and mild hypertelorism with bilateral optic disc anomalies (Figure 2). A fundoscopic exam confirmed morning glory disc anomalies (Figure 3).
Fundus examination revealed a normal optic disc within a slight staphyloma in
the right eye as well as normal macula and vessels. In the left eye, there
was a Morning Glory Disc (large and excavated with vessels leaving from the
side with the absence of central vasculature) surrounded by pigmentation
(black arrow) that extended to the macula. Please see online publication for
color images.
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AgCC, a large defect along the inferior sella turcica, consistent with the craniopharyngeal canal, with herniation of the adenohypophysis into a cephalocele protruding into the nasopharynx and mild hypertelorism with bilateral optic disc anomalies (Figure 2). A fundoscopic exam confirmed morning glory disc anomalies (Figure 3).