PMC5828374_01
Dorsum of left knee.
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fig1
These were mostly on his face, arms, and legs (Figure 1).
Low magnification view showing irregular epidermal acanthosis, with a prominent transepidermal defect containing cellular debris (hematoxylin and eosin stain, original magnification x40).
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fig2
A punch biopsy of one of the skin lesions revealed changes consistent with an acquired perforating dermatosis (APD) (Figures 2, 3, and 4).
Higher magnification showing the area of defect containing neutrophils, parakeratosis, and degenerating keratinocytes (hematoxylin and eosin stain, original magnification x200).
CRIN2018-5953069.003.jpg
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fig3
A punch biopsy of one of the skin lesions revealed changes consistent with an acquired perforating dermatosis (APD) (Figures 2, 3, and 4).
High magnification of the base of the defect showing perforation through the epidermis, and communicating with the superficial dermal collagen (hematoxylin and eosin stain, original magnification x400).
CRIN2018-5953069.004.jpg
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fig4
A punch biopsy of one of the skin lesions revealed changes consistent with an acquired perforating dermatosis (APD) (Figures 2, 3, and 4).