PMC8180893_01
Neurobiological systems engineering model of the relationship of pain, pleasure and opioid tone.
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F1
CPT of 39 s a week later. CPT falling from 190 s to 28 or 39 s is thought to represent decreased central nervous system opioid tone, moving A toward the top of the inverse parabolic function in Figure 1. Closeness caused pleasure rather than pain.