PMC6418023_01
CT showed a large, regular, hypodense 22 x 18 x 9 cm mass in the left lateral lobe of the liver (A-C). Blood vessels were observed in the tumor in the arterial phase (B,C), and the tumor was progressively unevenly enhanced in the portal vein phase (D) and in the delayed phase (E). The liver tissue adjacent to the tumor was weakly enhanced (F).
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F1
Abdominal computed tomography (CT) showed a large 22 x 18 x 9 cm regular hypodense mass in the left lateral lobe of the liver that was progressively enhanced after infusion of contrast material, with blood vessels observed in the tumor (Figure 1).
The lesion showed a slightly decreased signal intensity on T1-weighted images (A) and a slightly increased signal intensity on T2-weighted images (B,C). A progressive uneven enhancement was observed after the infusion of contrast material (D-F).
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F2
Progressive, uneven enhancement was observed (Figure 2).
A microscopic examination revealed that the tumor consisted of spindle cells with vascular proliferation in the myxoid stroma (A,B). Immunohistochemistry showed strong and diffuse staining for CD34 (C), SMA (D), and Ki67 at ~2% (E), and showed more negative staining in the neoplastic cells (left black arrow) but positive the in normal liver cells (right white arrow) for CK (F).
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F3
Immunohistochemistry showed strong and diffuse staining for CD34, smooth muscle actin (SMA) and Ki67 (2%) and negative staining for Estrogen receptor (ER), C-keratin (CK), and Desmin (Figure 3).