PMC10277476_01
(A) The patient developed a subcutaneous induration in the abdominal wall. Redness, swelling, and pain worsened within 4 days. (B) Abdominal-wound tissue necrosis; ulcerated area: 2x2 cm. (C) Abdominal-ulcer worsened; ulcerated area: 10x10 cm. (D) The skin lesions had a poor response to the antibiotic treatment. (E-G). After treatment with prednisone, the patient's crater-like ulcer gradually healed.
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At hospital admission, the size of the abdominal wall induration had reached 10x10 cm2 ( Figure 1A ). However, the skin erythema and induration gradually progressed to become ulcers ( Figure 1B ). However, the patient's skin lesions continued to expand ( Figure 1C ). His skin lesions had a poor response to antibiotic treatment ( Figure 1D ). The ulcer then gradually closed and the wound healed one month later ( Figures 1E-G ).
Record of drug use.
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We then further switched his antibiotics to piperacillin-tazobactam and sulfamethoxazole ( Figure 2 ).
Muscle and adipose-tissue pathology results: diffuse and extensive neutrophil infiltrations.
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The pathological report showed diffuse neutrophil infiltrations in the muscle and adipose tissue without lymphoma cells ( Figure 3 ).
Positron emission tomography/computed tomography examination. The tumor was in remission without radiographic recurrence. (1) There was no increase in lesion metabolism in the original mediastinal, neck, axillar, supraclavicular, and internal mammary areas; the Deauville score was 1, which was considered complete remission after treatment. (2) Left upper-arm and lower-left abdominal-wall skin and subcutaneous inflammatory changes.
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In addition, a positron emission tomography/computed tomography examination showed a negative result for lymphoma ( Figure 4 ).