PMC6135151_01
Picture showing erythema, edema, and desquamation on both feet. The patient had also milder erythema and complaints such as pruritus, redness, and impaired sensitivity on both hands, being diagnosed with palmar-plantar erythrodysesthesia
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F1
Grade 2 hand-foot syndrome or palmar-plantar erythrodysesthesia (PPE) was diagnosed [Figure 1], and the patient was given topic medication - Neo-Cortisone Cream (hydrocortisone 1% and neomycin Sulfate 0.5%) and Doxepin Hydrochloride Cream 5%, 3-4 times/day - and advised to avoid extreme temperatures and excessive pressure or friction to the skin.