PMC9450529_01
Aspect of cutaneous nodule removed from the dermis of submandibular region (2nd lesion).
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Eight months after, she presented nodular lesion (Figure 1), measuring 0.7 cm diameter, reddish, non-bleeding and pruruginous on the skin of submandibular left region, 1.5cm from the surgical scar.
Small tumor in parotid region (3rd lesion). We can also observe the surgical scars of previous lesions removed.
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Six weeks later, the patient presented a small tumor on the left parotid region (Figure 2).
Infiltrative glandular epithelial aspect of neoplasm (N). AP: parotid acines. (HE, objective 4X).
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Parotid and skin lesions on submandibular region presented the following histopathological aspects of neoplastic tissues: presence of infiltrative glandular epithelial neoplasm (Figure 3), presenting polygonal or rounded cells placed in glandular disposition, of variable size and complexity.
Arrow: secretion by apical decapitation (HE, objective 40X).
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We evidenced the presence of apical decapitation secretion (Figure 4), characteristic of apocrine glands in most tumor cells.