PMC8349101_01
Follow-up CT acquired one year after mastectomy and adjuvant chemo-radiotherapy. Abdominal axial CT images show multiple hypodense liver lesions (black arrows) with ring enhancement, due to metastatic disease, well depicted at third (a) and second (b) hepatic segments. Axial (c) and coronal (d) HRCT images do not demonstrate any pulmonary involvement.
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A CT examination, acquired 12 months after the end of treatment, has shown the onset of multiple liver metastasis; no other organs were involved by disease dissemination (Fig. 1).
Follow-up CT performed after second line treatment. Axial CT images (a, b) show the complete disappearance of the lesions in the left hepatic lobe (black asterisk).
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A multidisciplinary evaluation was done and a second line of treatment was performed, adding to the previous treatment a biological therapy based on trastuzumab and pertuzumab; CT scan - performed three months later - revealed complete resolution of disease with disappearance of hepatic lesions (Fig. 2).
Follow-up CT. Axial CT images show the radiological stability of the patient, with no evidence of metastasis in the liver (a, b) and in the lungs (c, d).
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The following CT examinations have demonstrated the patient's stability over a few years, with no evidence of metastasis (Fig. 3).
Axial (a, b) and coronal (c) HRCT images reveal the presence of multiple bilateral cavitated nodular lesions, having a predominant centrilobular and peribronchial distribution, with no gradient between upper and lower regions.
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In some cases, they were ill-defined with a perilesional area of ground-glass attenuation (Fig. 4).