PMC7067121_01
Positron emission tomography-magnetic resonance imaging fusion with T1 radial volumetric interpolated breath-hold examination with fat suppression acquired in the axial plane showed severely decreased radiotracer activity throughout the liver parenchyma (white arrow) (a). Corresponding axial T1 radial volumetric interpolated breath-hold examination with fat suppression image (b) revealed generalized decreased magnetic resonance signal in the liver. Axial positron emission tomography attenuation corrected image (c) showed severe decreased liver uptake (black arrow) which was not present on the nonattenuation corrected images (d)
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F1
The mean standard uptake value (SUV) of the liver was 0.6 [Figure 1].
Dixon three-dimensional volumetric interpolated breath-hold examination T1-weighted magnetic resonance sequence in the coronal plane demonstrates normal signal intensity in the liver parenchyma (arrow) on the out-of-phase image (a) with drop in signal on the in-phase image indicating excessive iron accumulation (b). The mu map showed the expanded boundary of the right lung instead of the correctly assigned soft-tissue density of the liver parenchyma (curved arrow) (c)
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F2
As a consequence, the generated mu maps for this patient expanded the boundary of the right lung instead of correctly assigning soft-tissue density to the liver parenchyma [Figure 2].
The coronal attenuation mu map was manually segmented by filling in the faulty liver reconstruction (thin arrow) with soft-tissue density instead of lung tissue (a). The resulting attenuation corrected positron emission tomography image in the coronal plane showed the properly corrected liver parenchyma tracer activity (thin arrow). Unrelated to the liver, multiple osseous metastases are noted on the study (arrowheads) (b)
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F3
The resulting attenuated corrected PET image showed the properly corrected liver parenchyma tracer activity with mean SUV 2.4 [Figure 3].
Fluorodeoxyglucose positron emission tomography-magnetic resonance imaging scan after oral chelator therapy with attenuation corrected positron emission tomography axial image demonstrating normal fluorodeoxyglucose uptake within the liver (a). Corresponding T1 radial volumetric interpolated breath-hold examination with fat suppression image showed improved liver signal intensity reflecting decreased iron deposition (b)
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F4
Likewise, the corresponding T1 image showed improved liver signal intensity reflecting decreased iron deposition [Figure 4].