PMC7705285_01
(A) Inflammation and induration of a large black ink tattoo over right arm and chest;
tattoo was inked 1 year prior to presentation. (B) Resolution of inflammation after
systemic steroid use.
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Rocky Mountain Regional Veterans Affairs Medical Center for evaluation of several months of bilateral eye redness and blurry vison. Review of systems was notable for simultaneous onset of diffuse erythema, tenderness, induration, and pruritus of a large black ink tattoo over the right arm and chest (Figure 1).
(A/B) Unaffected tattoos performed 10 years prior to presentation.
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He had 2 other tattoos completed 10 years before, which were unaffected (Figure 2).
(A) Slit lamp examination of the left eye revealing iris synechia (head arrow). (B)
Optical coherence tomography of the left eye macula showing macular edema
(asterisks).
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On optical coherence tomography, there was evidence of macular edema (Figure 3).
Histology from punch biopsies of the affected skin (hematoxylin and eosin stain at x4
[A] and x20 [B] power) showing evidence of granulomatous inflammation (arrows) with
associated tattoo ink deposition (asterisks) consistent with foreign body-type
granulomatous reaction.
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Histological examination revealed granulomatous inflammation with associated tattoo ink deposition consistent with foreign body-type granulomatous reaction (Figure 4).