PMC8556652_01
Plain Chest X-Ray of 68 years old woman with mediastinal angiolipoma. Plain Chest X-Ray showed a right paratracheal mass (arrows) with a well-demarcated lesion attached to the mediastinal cage.
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Chest X-Ray revealed a regular mass in the right paratracheal (Fig. 1). Contrast-Enhanced Computed Tomography (CECT) of the chest showed a lobulated mass in posterior media mediastinum attached to right 3rd-5th thoracal rib with pleural effusion and cardiomegaly (Fig. 2a and b).
Contrast-enhanced Computed Tomography. (a) axial view (b) sagittal view. Figures (a) and (b) showed a lobulated lesion in the right medial posterior intrathoracic with an attachment to the right 3rd-5th vertebral body and mild right pleural effusion.
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Chest X-Ray revealed a regular mass in the right paratracheal (Fig. 1). Contrast-Enhanced Computed Tomography (CECT) of the chest showed a lobulated mass in posterior media mediastinum attached to right 3rd-5th thoracal rib with pleural effusion and cardiomegaly (Fig. 2a and b).
Follow-up contrast-enhanced CT in 12th January 2018 (a) axial view (b) coronal view. Figures (a) and (b) showed a lobulated mass in the right medial posterior intrathoracic mass attached to the 3rd-5th vertebrae body with size 5x3.2 x 2.8cm and without connection to the spinal canal. There is no destruction of vertebrae bone. Compared with recent Chest CT, there was no significant gain of mass.
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CT three months later presented hypodense lobulated mass, measuring 5 x 3.2 x 2.8cm in right posterior medial mediastinum attached to 3rd-5th rib without any attachment to the spinal nerve and any destruction in spinal bone. Compared with the previous CECT, there was a minimally progressed tumor (Fig. 3a and b).
(A) Angiolipoma features of HE staining showed mature adipose tissue surrounded by blood vessels nest (B) Immunohistochemistry S100 showed positive of adipose cells (C) Ki67 index revealed low proliferation typical for a benign lesion.
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Histopathology preparation revealed mature adipose tissue with multiple small blood vessels with Hematoxylin-Eosin (HE) staining (Fig. 4A). Further examination with Immunohistochemistry S100 showed positive adipose cells (Fig. 4B) and the Ki67 index revealed low proliferation, typical for benign lesions (Fig. 4C).
Follow up contrast-enhanced CT in 20th February 2020 (a) axial view (b) coronal view. Figures (a) and (b) showed normal appearance of the mediastinal window with no sign of tumor occurrence or any other abnormalities.
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Followed up CECT 3 years later confirmed the absence of tumour recurrence (Fig. 5).