PMC4275023_01
Immunofluorescence showing strong positive for IgA in the capillary loop and mesangium.
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The presence of an active urinary sediment (urine albumin 3+ by dipstick and microscopic hematuria) necessitated a renal biopsy which showed IgA nephropathy ( Figure 1) with an Oxford Pathological score of M1E0S1T1, 5/10 glomerular sclerosis and 30% IF/TA with hypertensive changes in blood vessels ( Figure 2).
Hematoxylin and eosin staining showing tubular atrophy, interstitial fibrosis and thickened blood vessel.
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The presence of an active urinary sediment (urine albumin 3+ by dipstick and microscopic hematuria) necessitated a renal biopsy which showed IgA nephropathy ( Figure 1) with an Oxford Pathological score of M1E0S1T1, 5/10 glomerular sclerosis and 30% IF/TA with hypertensive changes in blood vessels ( Figure 2).