PMC6886625_01
Chest radiographs showing a dropped heart and lung hyperinflation which appeared soon after symptom onset. CTR: cardiothoracic ratio
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Chest radiography revealed a dropped heart and a hyperinflated lung which developed after symptom onset (Fig. 1).
CT of the abdomen showing intraperitoneal lymph nodes still present but reduced in size
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CT of the whole body showed bulky intraperitoneal lymph nodes reduced in size, with other previously enlarged lesions now normalized (Fig. 2).
CT of the chest showing a mosaic pattern of air trapping enhanced at the expiratory phase (chest CT before chemotherapy was normal)
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High-resolution CT (HRCT) of the chest revealed bronchial dilatation and a mosaic pattern consisting of high- and low-density areas that represented bronchiolar air trapping, which was enhanced at the end-expiratory phase, although CT of the chest before chemotherapy had not demonstrated abnormal findings (Fig. 3).
Pulmonary function testing with a bronchodilator revealing severe obstructive and restrictive failure without bronchodilator response
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Pulmonary function testing (PFT) revealed severe obstructive and restrictive failure (forced expiratory volume in 1 s, 19% of predicted; forced vital capacity, 43.9% of predicted) without bronchodilator response (Fig. 4).
Pulmonary ventilation and perfusion scintigraphy revealing a mosaic pattern of radio-isotope uptake decrease without ventilation-perfusion mismatch
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PFT results had been normal several years previously. Pulmonary ventilation and perfusion scintigraphy revealed a mosaic pattern of radio-isotope uptake decrease without ventilation-perfusion mismatch (Fig. 5).