PMC6010638_01
Chest computed tomography scan image for case 1 showed lung cavity with a fungus ball in the left lower lobe (A). Interstitial pneumonia was also detected in the bilateral lower lobes (B). Specimens obtained via bronchoscopy revealed the aggregation of malignant cells with irregular papillary and tubular structure, suggesting adenocarcinoma (C, hematoxylin and eosin staining, x 100). The filamentous fungus with positive Grocott staining was detected in the same specimens, suggesting pulmonary aspergillosis (D, Grocott staining, x 100).
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fig1
A chest computed tomography (CT) scan revealed lung cavity with a fungus ball in the left lower lobe (Fig. 1A) along with bilateral interstitial pneumonia (Fig. 1B). The specimens obtained by bronchoscopy showed adenocarcinoma with hematoxylin and eosin staining (Fig. 1C) and filamentous fungus with positive Grocott staining (Fig. 1D).
PMC6010638_02
Chest computed tomography scan revealed reticulonodular shadow in the middle lobe/lingular segment (A). Cavity formation with daughter nodules was also detected in the right middle lobe (B). Specimens taken by surgical resection revealed malignant cells with papillary and tubular structure. Epithelioid granulomas with focal necrosis were located around the bronchus (C, D, hematoxylin and eosin staining, x 100).
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CT scan revealed a reticulonodular shadow in the middle lobe/lingular segment (Fig. 2A). Cavity formation with daughter nodules was detected in the middle lobe (Fig. 2B), and the patient was suspected to have NTM lung disease. The specimens showed adenocarcinoma on hematoxylin and eosin staining (Fig. 2C) and epithelioid granulomas with focal necrosis, which suggested mycobacterial infection (Fig. 2D).