PMC3747418_01
Magnetic resonance imaging of the abdomen showing bilateral renal infiltration. T2-weighted fat-saturated magnetic resonance imaging of the abdomen. (a) Coronal view shows bilateral renal infiltration (arrowheads). (b) Transverse cross-section shows bilateral renal infiltration (arrowheads), unilateral right hydronephrosis, and pancreatic involvement (arrow).
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fig1
The kidneys had a diffuse nodular appearance with T2 hyperintensity seen on magnetic resonance imaging (MRI), with an exophytic circumscribed homogeneous left renal mass (5.4 x 4.6 cm) (Figure 1).
Kidney biopsy showing lymphoblastic infiltration. (a) Histology shows the interstitial lymphoblastic infiltrate surrounding the glomeruli and tubules (x200 magnification). (b) Hematoxylin and eosin stain of the lymphoblasts (x630 magnification). (c) Immunohistochemistry with cells expressing CD79 with cytoplasmic staining (x400 magnification). (d) Immunohistochemistry with cells expressing TdT with nuclear staining (x400 magnification). These findings are typical of lymphoblasts.
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fig2
The kidney was infiltrated with medium-sized neoplastic lymphoid cells expressing TdT, CD79a, CD43, and CD23 (Figure 2).