PMC6000910_01
Esophagogastroduodenoscopy (EGD), esophagography, and CT findings of esophageal cancer. (a) EGD revealed a circumferential mass in the upper intrathoracic esophagus, 21-24 cm from the incisors. (b) Esophagography revealed stenosis and wall irregularity in the upper intrathoracic esophagus. (c) CT demonstrated left recurrent nerve lymph node (#106recL) swelling (arrow).
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Esophagogastroduodenoscopy (EGD) revealed a circumferential mass in the upper intrathoracic esophagus, 21-24 cm from the incisors (Fig. 1a). Esophagography revealed stenosis and wall irregularity in the upper intrathoracic esophagus (Fig. 1b). CT scans demonstrated swelling of the left recurrent nerve lymph node (#106recL) (Fig. 1c). Adenocarcinomas were also identified in regional lymph nodes of the esophagus, #106recL (Fig. 5a), #108, #110, #1, #2, and #7.
PET-CT and MRI findings after chemotherapy. (a) PET-CT showed accumulation in the liver of segment III [maximum SUV of 4.3] (arrow). (b) MRI revealed nodules in the liver of segment III (10 mm in diameter) and multiple small nodules (2-3 mm in diameter) in the liver (arrows).
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PET-CT showed the fluorodeoxyglucose accumulation in the liver of segment III (maximum SUV of 4.3) (Fig. 2a). MRI revealed nodules in the liver of segment III (10 mm in diameter) and multiple small nodules (2-3 mm in diameter) in the liver (Fig. 2b). Adenocarcinomas were also identified in regional lymph nodes of the esophagus, #106recL (Fig. 5a), #108, #110, #1, #2, and #7.
Macroscopic and microscopic findings of the resected specimen. (a) Resected specimens of the esophagus and stomach. (b) Resected specimen of the esophagus showed a 30 x 20 mm lesion of unclassifiable type. (c) Hematoxylin and eosin stain. The tumor invaded the adventitia. (d) Hematoxylin and eosin stain. The tumor was well differentiated squamous cell carcinoma.
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The resected specimen showed a 30 x 20 mm lesion which could not be classified (Fig. 3a, b). Histopathological examination of the esophagus revealed well differentiated squamous cell carcinoma with invasion of the adventitia (Fig. 3c and d).
The liver tumor was adenocarcinoma (a) hematoxylin and eosin stain. Tumor cells were positive for ER (b) and GATA-3 (c), but negative for p63 (d).
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The nodules on the peritoneum and liver of segment III were adenocarcinomas (Fig. 4a). On immunohistochemical examination, tumor cells in the liver, peritoneum, and 106recL lymph node were positive for ER and transcription factor GATA3, but negative for tumor protein p63 (Fig. 4b-d, 5b-d).
The #106recL lymph node tumor was adenocarcinoma (a) hematoxylin and eosin stain. Histological appearances were similar to those of the liver tumor. Tumor cells were positive for ER (b) and GATA-3 (c), but negative for p63 (d).
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Adenocarcinomas were also identified in regional lymph nodes of the esophagus, #106recL (Fig. 5a), #108, #110, #1, #2, and #7. On immunohistochemical examination, tumor cells in the liver, peritoneum, and 106recL lymph node were positive for ER and transcription factor GATA3, but negative for tumor protein p63 (Fig. 4b-d, 5b-d).