PMC5560510_01
Histopathologic examination of breast mass in patient 1. (A) Diffuse proliferation of atypical large lymphoid cells in breast tissue (hematoxylin-eosin, original magnification x40). Immunohistochemical studies demonstrate that atypical large cells are (B) positive for CD20 and (C) positive for BCL2. (D) Ki67 shows high proliferation rate of lymphoma cells.
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PMC5560510_01_10.1177_1179545X17725034-fig1.jpg
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The patient underwent breast biopsy and was found to have DLBCL (Figure 1), activated B-cell subtype, International Prognostic Index (IPI 3), with no central nervous system (CNS) involvement by cerebrospinal fluid (CSF) examination.
PMC5560510_02
PMC5560510_03