PMC5610687_01
FLAIR weighted image showing multiple sclerosis lesions distributed mainly periventricularly and a hyperintense lesion in the fronto-parietal region that extends to the cortex, suggestive of progressive multifocal leukoencephalopathy.
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F1
Robot output and functional MRI activation in pre (red) and post (blue) rehabilitation period. (A,B) on the left (red squared), the reaching trajectories before the robot-assisted rehabilitation; on the right (blue squared), the same trajectories after a 3-week period of robot-therapy. (C,D) Maxima of regions showing significant activations during the Observational task (C) and motor task (D) in pre:red areas:and post:blue areas:conditions. Transverse slice view (on a 152 T1 xjview template) of significant positive activation (thresholded at P FWE corrected <0.05 with k > 50 voxels).
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F2
The task was center-out reaching movement, from one central target to five peripheral targets arranged on a semi-circle with a 20 cm radius (Figure 2A). Brain regions with significant activation in the Pre vs Post MDR are summarized in Table 2 and shown in Figure 2.