PMC4172876_01
MRI demonstrates solid mass lesion in left parotid gland. Fat-suppressed T2-weighted images show mild hyperintensity, T1-weighted images show hypointensity, and postcontrast images show low contrast enhancement.
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A 3.5 cm solid lobulated mass lesion with a soft edge property in the left parotid gland was identified on MRI (fat-suppressed T2-weighted images showed mild hyperintensity, T1-weighted images showed hypointensity, and postcontrast images showed low contrast enhancement) (Figure 1).
Myoepithelial cells with smooth muscle actin (SMA) positivity on immunohistochemistry x200 (a). There are bilayered tumor cells in the basal layer, the outer myoepithelial cells have a clear appearance, and the inner epithelial cells have lumen formation with hematoxylin and eosin x200 (b).
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Immunohistochemical staining showed SMA (+), P63 (+), CK8 (+), and S100 (+) on epithelial cells (Figure 2).
Epithelial-myoepithelial carcinoma and adenocarcinoma (NOS) in the same aspect, hematoxylin and eosin x100 (a). Adenocarcinoma appearance which had solid structure and rare glandular structures together, hematoxylin and eosin x100 (b).
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After histopathologic analysis, foci of epithelial-myoepithelial carcinoma and poorly differentiated adenocarcinoma (not otherwise specified; NOS) with clear cytoplasm were seen in the parotid gland (Figure 3).