PMC3469228_01
Fluctuation of estradiol (E2) levels after dilatation and curettage.. Note: The periodic increase and decrease of the E2 levels are seen in follicle-stimulating hormone-secreting adenoma in an approximate 6-week cycle.. Abbreviation: D and C, dilatation and curettage.
ijwh-4-427f1.jpg
PMC3469228_01_ijwh-4-427f1.jpg
f1-ijwh-4-427
Due to the diagnostic delay, transition of E2 levels was closely monitored and showed periodical fluctuation (Figure 1).
Fluctuation of estradiol (E2) levels after dilatation and curettage. The periodic increase and decrease of the E2 levels are seen in follicle-stimulating hormone (FSH)- secreting adenoma in an approximate a 6-week cycle.. Note: Buserelin acetate nasal spray was administered three times per day for 8 weeks (daily dose, 900 mug).. Abbreviations: GnRHa, gonadotropin-releasing hormone agonist; LH, luteinizing hormone.
ijwh-4-427f2.jpg
PMC3469228_01_ijwh-4-427f2.jpg
f2-ijwh-4-427
In addition, GnRH agonist treatment exacerbated the symptoms and increased E2 levels (Figure 2).
Magnetic resonance imaging (MRI) and immunohistochemical findings of the two cases. (A and D) T1-weighted MRI images of Cases 1 and 2, respectively. Pituitary tumor was seen in each case. (B and E) Immunohistochemistry for follicle-stimulating hormone (FSH) in pituitary tumors derived from Cases 1 and 2, respectively. Positive staining for FSH was done for each specimen. (C and F) Immunohistochemistry for LH in pituitary tumors derived from Cases 1 and 2, respectively.. Note: Negative staining for luteinizing hormone was seen in each specimen.
ijwh-4-427f3.jpg
PMC3469228_02_ijwh-4-427f3.jpg
f3-ijwh-4-427
After an MRI scan revealed a pituitary tumor, transsphenoidal resection of the tumor ameliorated the symptoms (Figure 3D).
PMC3469228_02
Magnetic resonance imaging (MRI) and immunohistochemical findings of the two cases. (A and D) T1-weighted MRI images of Cases 1 and 2, respectively. Pituitary tumor was seen in each case. (B and E) Immunohistochemistry for follicle-stimulating hormone (FSH) in pituitary tumors derived from Cases 1 and 2, respectively. Positive staining for FSH was done for each specimen. (C and F) Immunohistochemistry for LH in pituitary tumors derived from Cases 1 and 2, respectively.. Note: Negative staining for luteinizing hormone was seen in each specimen.
ijwh-4-427f3.jpg
PMC3469228_02_ijwh-4-427f3.jpg
f3-ijwh-4-427
After an MRI scan revealed a pituitary tumor, transsphenoidal resection of the tumor ameliorated the symptoms (Figure 3D).