PMC5610806_01
Transverse (a) and longitudinal (b) ultrasonography images showing a solid hypoechoic and heterogeneous mass with microlobulated contours, measuring 3.6 cm x 2.9 cm x 2.3 cm, with long transversal axis of the external superior quadrant of the right breast (collection of the Department of Imaging, the University Teaching Hospital of Lome).
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fig1
Ultrasonography showed an oval hypoechoic, heterogeneous mass with microlobulated contours, measuring 3.6 cm x 2.9 cm x 2.3 cm, with long transverse axis (Figure 1).
Neuroendocrine carcinoma of the breast (HES; x100): tumoral diffuse proliferation due to medium and large cells invading the gland and oppressing lobules and ducts (collection of the Pathological Anatomy Laboratory, the University Teaching Hospital of Lome).
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fig2
On conventional histological examination, a diffuse tumor proliferation, made up of small round cells with hyperchromatic nucleus and a scant limited amphophilic cytoplasm, massively infiltrating the gland and penetrating the lobules and channels (Figure 2) was observed.
Neuroendocrine carcinoma of the breast (IHC; x100): chromogranin A test positive for neuroendocrine tumor cells and negative for leukocyte markers (collection of the Pathological Anatomy Laboratory, the University Teaching Hospital of Lome).
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fig3
The leukocyte markers were negative (Figure 3).