PMC3702545_01
Right (A) and left (B) fundus photographs showing diffuse optic disc pallor in both eyes.
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The fundus examination showed diffuse optic disc pallor in both eyes (Figure 1A and B).
Right (A) and left (B) Goldmann perimetry showed constriction of the I/2 e isopter in both eyes.
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Visual field testing with a Goldmann perimeter showed constriction of the I/2 e isopter in both eyes (Figure 2A and B).
Results of right (A-F) and left (G-L) white-on-white perimetry (A-C and G-I) and blue-on-yellow perimetry (D-F and J-L). Gray-tone scale (A, D, G, and J), total deviation map (B, E, H, and K) and pattern standard deviation map (C, F, I, and L) for white-on-white and blue-on-yellow perimetry. Note that blue-on-yellow perimetry captured the visual field abnormalities more effectively than white-on-white perimetry.
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The results of blue-on-yellow perimetry were less precise than those obtained using white-on-white perimetry (-13.18 dB right, -10.01 dB left versus -1.26 dB right, -1.83 dB left) (Figure 3). The pattern standard deviation was also worse with blue-on-yellow perimetry versus white-on-white perimetry (3.89 dB right, 4.03 dB left versus 1.78 dB right, 1.76 dB left) (Figure 3).
Right (A-C) and left (D-F) optical coherence tomography scans showing decreased retinal thickness.. Notes: A and D: RNFL map, B and E: RNFL + GCL + IPL map (9.0 mm), C and F: RNFL + GCL + IPL map (1.5/4.5/9.0 mm).. Abbreviations: RNFL, retinal nerve fiber layer; GCL, ganglion cell layer; IPL, inner plexiform layer; T, temporal; S, superior; N, nasal; I, inferior.
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The results showed decreased retinal thickness at each measurement point (Figure 4). In the right eye, mean RNFL thickness at the temporal, superior, nasal, and inferior quadrants was 47, 93, 60, and 75 mum, respectively. In the left eye, these values were 47,110,41, and 96 mum, respectively (Figure 4A and D).