PMC9891147_01
a Esophageal biopsy showing a dense lymphoplasmacytic infiltrate with perivascular disposition and fibrosis. HE. x200. Immunohistochemical staining with IgG (b, x200) and IgG4 (c, x200), with an IgG4/IgG ratio >40%.
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F1
Biopsies were performed, and histopathology revealed a probable IgG4-associated esophagitis due to lymphoplasmacytic infiltrate with large numbers of positive IgG4 plasma cells (>200/high power field), IgG:IgG4 ratio greater than 50%, nonobliterative phlebitis, and mild fibrosis, without storiform pattern (Fig. 1).
PMC9891147_02
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