PMC7158931_01
Color fundus image of the left eye showing (a) retinal edema, retinal arterial attenuation, and cherry-red spot at macula, suggesting central retinal artery occlusion at the time of presentation. (b) at the last visit, fundoscopy showing optic atrophy, generalized retinal arterial attenuation, and retinal atrophy at the macula, confirmed on optical coherence tomography
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F1
Fundus examination of the LE revealed a generalized retinal edema, retinal arterial attenuation, and the presence of a cherry-red spot at the posterior pole, suggesting CRAO of the LE [Figure 1a]. Fundus examination of the LE revealed optic atrophy, generalized retinal arterial attenuation, and retinal atrophy at macula, which was confirmed on optical coherence tomography [Figure 1b].
T1-weighted gadolinium contrast-enhanced magnetic resonance imaging images of the brain, orbit, and paranasal sinuses showing (a) enhancing soft tissue involving the left ethmoid sinus (red arrow) with its extension into the left orbit involving medial and inferior recti muscles (green arrow), surrounding the optic nerve (yellow arrow) and the left frontal lobe abscess (blue arrow). (b) Axial image showing enhancing soft tissue involving the orbital apex and infiltrating into the left cavernous sinus, causing its thrombosis (blue arrow). (c) Biopsy specimen showed growth of Rhizopus on lactophenol cotton blue mount
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F2
A magnetic resonance imaging (MRI) scan of the brain and orbit [Figure 2a and b] showed enhancing soft tissue in the left ethmoid sinus eroding the fovea ethmoidalis and lamina papyracea with soft-tissue extension into the left orbit involving medial and inferior recti muscles and surrounding the optic nerve. Culture of the biopsy specimen from the sinuses showed Rhizopus oryzae on Sabouraud's dextrose agar [Figure 2c].