PMC10103709_01
Clinical features and treatment response of SLEP. (A) A solitary firm to hard erythematous plaque mimicking dermatofibrosarcoma protuberans on the left lateral neck. (B) Partial improvement with indentation after treatment with intralesional steroid and hydroxychloroquine (200 mg/day).
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Dermatological examination revealed a solitary indurated erythematous plaque with firm to hard consistency on the left lateral side of the neck (Figure 1A), and a faint erythematous plaque with telangiectasia at the left lateral nose. At 2-month follow-up, the lesions showed partial improvement with some indentation (Figure 1B).
Histopathologic features of SLEP. (A) dense superficial and deep perivascular and periadnexal infiltration composed of lymphocytes and plasma cells (H&E, x40) (B) thickened homogenized dermal collagen with lobular panniculitis (inset, H&E, x100).
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In addition, thickened homogenized collagen in the lower dermis extending to the broadened fibrous septum and loss of adipocytes around eccrine structures were noted (Figure 2).