PMC3325736_01
The tumor had a complex papillary pattern with epithelial stratification and tufting with the formation of cellular buds. In the nonpapillary parts, the tumors cells had a predominantly glandular growth pattern and scattered psammoma bodies.
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F1
We performed a biopsy of the uterine tumor and obtained a diagnosis of PSCC microscopically (Figure 1).
A computed tomography scan revealed the swelling of multiple lymph nodes on bilateral sides (arrows) of the patient's neck.
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F2
CA 125 level was elevated at 2480 U/mL (normal range <35 U/mL). Computed tomography (CT) scan revealed the swelling of multiple lymph nodes on bilateral sides of the patient's neck (Figure 2).
T2-weighted sagital magnetic resonance imaging showed an enlarged uterine cervical mass and vaginal invasion to one third of the inferior parts (arrows).
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F3
Magnetic resonance imaging (MRI) showed an enlarged uterine cervical mass and vaginal invasion to one third of the inferior parts (Figure 3).
T2-weighted sagital magnetic resonance imaging showed an almost complete response based on the response evaluation criteria after the chemotherapy.
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F4
MRI also showed remarkable reduction of the uterine cervical tumor and vaginal masses (Figure 4).
Almost all of the carcinoma cells had disappeared, except for a small focus of atypical cells in the cervical stroma microscopically.
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F5
Re-biopsy of the uterine cervix demonstrated that nearly all of the carcinoma cells had disappeared, except for a small focus of atypical cells in the cervical stroma (>95% of the malignant cells had disapperared; Figure 5).