PMC9514041_01
Skin appearance 4 weeks after the onset of skin reaction.
fphar-13-994865-g001.jpg
PMC9514041_01_fphar-13-994865-g001.jpg
F1
Upon readmission, large erythema and bullae along with exudate and pus appeared in front of the tibia, the skin lesions on the thighs had basically crusted, and edema on both legs and feet was obvious, as shown in Figure 1.
Evolution of clinical events and skin changes. uHCC, unresectable hepatocellular carcinoma; BID, twice daily; pip/tazo, piperacillin/tazobactam.
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PMC9514041_01_fphar-13-994865-g002.jpg
F2
The timeline of this severe cutaneous adverse reaction and partial skin healing process are summarized in Figure 2.