PMC9817488_01
Cytological features of the Warthin tumor showing oncocytic cell clusters. (A) Cytologic smear, MGG (100x). (B) Cell block, H&E (100x)
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The cytology showed evidence of a Warthin tumor (Figure 1).
Axial (A) and coronal (B) contrast-enhanced CT images showed a large enhancing tumor (arrows) in the left parotid gland
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A contrast-enhanced CT scan of the neck showed a 3.6 x 2.8 x 4.5 cm tumor in the left parotid gland (Figure 2).
(A, B) Histological features of the Warthin tumor, H&E (20x and 100x). (C, D) Histological features of the breast cancer metastasis in Warthin tumor, H&E (20x and 100x). Metastasis indicated with a circle and arrows. (E-G) Immunohistochemistry sections of the breast cancer metastasis stained for pancytokeratin (E), GATA3 (F) and estrogen receptor (G) (all images 20x). H&E, hematoxylin and eosin stain
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The final pathology report revealed that the tumor of the left parotid gland was a Warthin tumor containing two carcinoma metastases (Figure 3).
(A, B) Histological features of the breast tissue core biopsies showing primary invasive lobular carcinoma (ILC) H&E (20x and 100x). H&E, hematoxylin and eosin stain
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The core biopsy showed that the tumor was a Grade II lobular breast carcinoma with ER 95%, PR 0%, HER2 negative, and a proliferation rate (Ki-67) of 14% (Figure 4).