PMC2246146_01
A. Initial stage. Severe piecemeal necrosis and lobular damage with severe infiltration of lymphocytes and periportal and pericellular fibrosis. B. After drug withdrawal. Chronic hepatitis with mild activity and septal fibrosis.
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F1
Furthermore a severe infiltration of lymphocytes and neutrophils with scarce plasmatic cells and eosinophils, and periportal and pericellular fibrosis, were detected (figure 1A). Lobular liver cell damage ameliorated, no bridging necrosis or multiacinar necrosis was found and small regenerative hepatocytes were seen (figure 1B).