PMC3643364_01
(a) A malignant tumor cell cluster (Pap, x400); (b) The cell group in the left bottom shows nuclear pseudostratified strip reminiscent of short "bird tail like" arrangement (Pap, x400); (c) Spindle shaped tumor cells (Pap, x400); (d) Adenocarcinoma in submucosa (H and E, x100)
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F1
In addition, there were several atypical glandular cells with large hyperchromatic nuclei and thick cytoplasm [Figure 1a]. Cellular strips with nuclear pseudostratification, reminiscent of short "bird tail like" arrangements were also seen [Figure 1b]. Some tumor cells were spindle shaped similar to a high-grade anal intraepithelial neoplasia or squamous cell carcinoma [Figure 1c]. Histologic examination of the resected material demonstrated invasion of the muscularis propria by neoplastic glands [Figure 1d].