PMC10335281_01
Erythemas, lichenoid papules, scaly patches on his face, upper extremities and trunk (a and b). The scattered skin tags were mainly located on his upper extremities and trunk (b-d).
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Physical examination of the patient revealed erythemas, lichenoid papules, and scaly patches on his face, upper extremities, and trunk (Figure 1a and b). Scattered STs ranging between 3x2 and 10x8mm were mainly located on his upper extremities and trunk (Figure 1b-d).
The biopsies from the papule (a) and the skin tag (b) show a dense, band-like lymphocytic infiltrate in the papillary and mid-reticular dermis. The super-basal epidermis contained both single and small collections of lymphoid cells (Pautrier's collections) (c). Most of lymphoid cells are CD45RO-positive cells (d).
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Atypical lymphocytic infiltrate was also observed in the perivascular and skin appendages (Figure 2a-c). Immunohistochemical studies revealed that the atypical lymphocytes predominantly expressed CD4, CD45RO, and LCA (Figure 2d).