PMC5088545_01
(A) A light microscopic examination demonstrates segmental sclerosis around the vascular pole (arrow; Periodic acid-Schiff stain, scale bar=50 mum). (B) A light microscopic examination demonstrates focal fibrosis (Azan stain, scale bar=200 mum). (C) Immunofluorescence staining demonstrates the presence of IgM throughout the mesangial area (scale bar=100 mum). (D) Electron microscopy shows foot process effacement of the glomerular podocytes (arrowhead; scale bar=0.5 mum).
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PMC5088545_01_1349-7235-55-2831-g001.jpg
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Under electron microscopy, foot process effacement of the glomerular podocytes was observed, while electron dense deposits were absent (Fig. 1).
The patient's clinical course. The patient's levels of serum creatinine (dashed line) are shown against treatment and several clinical parameters: daily urine protein excretion (upper bar graph), urine output (lower bar graph) and levels of LDL (closed squares). HD: hemodialysis, mPSL: methylprednisolone, PSL: prednisolone
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The clinical course of the patient is shown in Fig. 2.