PMC4074982_01
(a) Esophagogastric junction histological sample (haematoxylin-eosin stain 10x). (b) Esophagogastric junction histological sample (haematoxylin-eosin stain 40x).
CRIS2014-489427.001.jpg
PMC4074982_01_CRIS2014-489427.001.jpg
fig1
Histopathological diagnosis was poorly differentiated adenocarcinoma (Figures 1(a) and 1(b)).
Mammography of bilateral breast.
CRIS2014-489427.002.jpg
PMC4074982_01_CRIS2014-489427.002.jpg
fig2
In mammography, a round shaped soft tissue opacity was seen in the upper and outer region of left breast and an oval shaped soft tissue opacity in the retroareolar region of right breast (Figure 2).
Left breast histological sample (haematoxylin-eosin stain 40x).
CRIS2014-489427.003.jpg
PMC4074982_01_CRIS2014-489427.003.jpg
fig3
The neoplastic cells were infiltrating into breast parenchyma and destroying terminal duct-lobular unit (Figure 3).
(a) Metastatic cells positive for CEA (40x). (b) Metastatic cells positive for CK 20 (40x).
CRIS2014-489427.004.jpg
PMC4074982_01_CRIS2014-489427.004.jpg
fig4
ER, PR, and Her-2-neu were negative, CEA and CK-20 were positive, and CK-7 was negative (Figures 4(a) and 4(b)). Endoscopy revealed stricture at 30 cm extending up to 38 cm.