PMC4665126_01
Spinal magnetic resonance imaging. (a) T2-weighted sagittal sequences showing the intramedullary lesion at T8-T9 level (yellow arrow), with solid (hypointense) and cystic (hyperintense) components. The cranial syringomyelia is evident (red arrow). (b) T2-weighted axial sequences demonstrating that the tumor is mainly located on the left spinal cord. T1-weighted sagittal (c) and axial (d) after gadolinium administration sequences showing the dishomogeneous contrast enhancement of the lesion
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F1
Spinal magnetic resonance imaging (MRI) with gadolinium showed an intramedullary lesion at T8-T9 level, with solid and cystic components, hypo- and hyper-intense on T2-weighted images and with dishomogeneous contrast enhancement after gadolinium administration associated to the cranial syrinx [Figure 1].
(a, x400) H and E stain of the lesion showing a neoplasm composed of round to oval cells with finely speckled chromatin pattern and small nucleoli. Ganglion cell differentiation was commonly present among neurocytic cells. (b, x400) Immunohistochemically, the neoplastic cells were positive for synaptophysin. The MIB-1 labeling index was 1% (not showed)
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F2
Hyalinized vessels were also observed [Figure 2a]. "Atypical" histological features (mitotic activity, microvascular proliferation, and necrosis) were not present. Immunohistochemically, the neoplastic cells were positive for synaptophysin [Figure 2b].