PMC5827465_01
An inadequate response in the ninth session (bilateral brief pulse ECT, Low 0.5, 100%), in which no motor seizure was observed, and the peak heart rate did not increase from the baseline.. Notes: EEG in channels 1 and 2, EMG in channel 3, and ECG in channel 4. The standard fronto-mastoid EEG electrode placements were used. The gain of the EEG amplifiers was set at 200 muV/cm, and the gain of the EMG and ECG amplifiers was set at 1,000 muV/cm.. Abbreviations: ECG, electrocardiogram; ECT, electroconvulsive therapy; EEG, electroencephalogram; EMG, electromyogram.
ndt-14-607Fig1.jpg
PMC5827465_01_ndt-14-607Fig1.jpg
f1-ndt-14-607
Although such stimulus levels produced mid-to-high-amplitude slow waves and apparent postictal suppression in the ictal electroencephalogram (EEG), neither motor seizures nor cardiovascular responses were observed (Figure 1).
Successful seizure induction following the third stimulation of the eleventh session (right unilateral ultrabrief pulse ECT, Low 0.25, 15%), in which a tonic-clonic motor seizure was first observed.. Notes: EEG in channels 1 and 2, EMG in channel 3, and ECG in channel 4. The standard frontomastoid EEG electrode placements were used. The gain of the EEG amplifiers was set at 200 muV/cm, and the gain of the EMG and ECG amplifiers was set at 1,000 muV/cm.. Abbreviations: ECG, electrocardiogram; ECT, electroconvulsive therapy; EEG, electroencephalogram; EMG, electromyogram.
ndt-14-607Fig2.jpg
PMC5827465_01_ndt-14-607Fig2.jpg
f2-ndt-14-607
A stimulus level of 15% enabled the induction of seizure activity, which involved tonic-clonic motor responses and was associated with low-to-mid-amplitude slow waves on EEG (Figure 2).
An adequate therapeutic seizure in the 16th session (right unilateral ultrabrief pulse ECT, Low 0.25, 100%), which was associated with high-amplitude slow waves and postictal suppression on the ictal electroencephalogram.. Notes: EEG in channels 1 and 2, EMG in channel 3, and ECG in channel 4. The standard frontomastoid EEG electrode placements were used. The gain of the EEG amplifiers was set at 200 muV/cm, and the gain of the EMG and ECG amplifiers was set at 1,000 muV/cm.. Abbreviations: ECG, electrocardiogram; ECT, electroconvulsive therapy; EEG, electroencephalogram; EMG, electromyogram.
ndt-14-607Fig3.jpg
PMC5827465_01_ndt-14-607Fig3.jpg
f3-ndt-14-607
In the subsequent sessions, the stimulus was increased to 100% (~6.7 times the ST), which produced adequate therapeutic seizures associated with high-amplitude slow waves and postictal suppression on the ictal EEGs (Figure 3).