PMC4199461_01
Coronal CT scan; sphenoid sinus in mid-level slices. Bone defect is noticed in the inferior third of the lateral wall of the left sphenoid sinus, and soft tissue with the same density as the brain tissue can be noticed beside the defect in the left sphenoid sinus.
poljradiol-79-360-g001.jpg
PMC4199461_01_poljradiol-79-360-g001.jpg
f1-poljradiol-79-360
Moreover, polypoid mass with the same density as the brain tissue beside the defect was seen in the left sphenoid sinus (Figure 1).
Contrast-enhanced T1W coronal (A) and axial (B) images: herniation of the temporal lobe into the sphenoid sinus is noticed (white arrows).
poljradiol-79-360-g002.jpg
PMC4199461_01_poljradiol-79-360-g002.jpg
f2-poljradiol-79-360
In brain MRI, intrasphenoidal encephalocele was seen (Figure 2).
Endoscopic image shows left intraspheniodal encephalocele via transsphenoidal approach. Posterior part of the middle turbinate, posterior etmoidal cells and anterior wall of sphenoid sinus were removed.
poljradiol-79-360-g003.jpg
PMC4199461_01_poljradiol-79-360-g003.jpg
f3-poljradiol-79-360
Incisional biopsy was taken from the polypoid mass in the sphenoid sinus (Figure 3).
(A) There is a mixture of mature astrocytes and glial fibers (star) in fibrovascular connective tissue underlying respiratory epithelium (arrow) x10 H&E. (B) GFAP-positive glial tissue x200 IHC.
poljradiol-79-360-g004.jpg
PMC4199461_01_poljradiol-79-360-g004.jpg
f4-poljradiol-79-360
The histological examination of the specimens taken from the sphenoid sinus revealed glial tissue in fibrovascular connective tissue fragments of mucosa coated by respiratory-type epithelium (Figure 4A). Immunohistochemical stains for glial fibrillary acidic protein (GFAP) and S-100 confirmed the diagnosis (Figure 4B).