PMC7677352_01
(A) A 68-year-old female with relapse of known Mantle cell lymphoma (MCL) resulting in swelling of the left sublingual gland. Magnetic resonance imaging (MRI) showing a tumor of the left sublingual gland (white arrow). (B) Histological image of the sublingual gland MCL (A). Salivary gland tissue is infiltrated by lymphoid tumor tissue and small tumor cells are seen with multiple membrane bound nucleoli. Ductal structures are seen (black arrow) (HE). (C) A 61-year-old male with 1-month history of painless swelling of the floor of the mouth. Tumor tissue was composed of neoplastic lymphoid cells with irregular nuclei and plasmacytic differentiation, consistent with a diagnosis of extranodal marginal zone lymphoma (EMZL) of the left sublingual gland. Scattered ductal structures are seen (black arrow) (HE). (D) Immunohistochemistry of the sublingual gland EMZL (C) showing positive reaction for lambda light chain. Scale bar = 50 mum.
fsurg-07-581105-g0001.jpg
PMC7677352_02_fsurg-07-581105-g0001.jpg
F1
A magnetic resonance imaging (MRI) of the head and neck was performed (Figure 1A). Histological examination of the excised sublingual gland showed salivary gland tissue infiltrated by lymphoid tumor cells appearing as blastoid cells with multiple membrane bound nucleoli (Figure 1B).
PMC7677352_02
(A) A 68-year-old female with relapse of known Mantle cell lymphoma (MCL) resulting in swelling of the left sublingual gland. Magnetic resonance imaging (MRI) showing a tumor of the left sublingual gland (white arrow). (B) Histological image of the sublingual gland MCL (A). Salivary gland tissue is infiltrated by lymphoid tumor tissue and small tumor cells are seen with multiple membrane bound nucleoli. Ductal structures are seen (black arrow) (HE). (C) A 61-year-old male with 1-month history of painless swelling of the floor of the mouth. Tumor tissue was composed of neoplastic lymphoid cells with irregular nuclei and plasmacytic differentiation, consistent with a diagnosis of extranodal marginal zone lymphoma (EMZL) of the left sublingual gland. Scattered ductal structures are seen (black arrow) (HE). (D) Immunohistochemistry of the sublingual gland EMZL (C) showing positive reaction for lambda light chain. Scale bar = 50 mum.
fsurg-07-581105-g0001.jpg
PMC7677352_02_fsurg-07-581105-g0001.jpg
F1
A magnetic resonance imaging (MRI) of the head and neck was performed (Figure 1A). Histological examination of the excised sublingual gland showed salivary gland tissue infiltrated by lymphoid tumor cells appearing as blastoid cells with multiple membrane bound nucleoli (Figure 1B).
PMC7677352_03