PMC9530806_01
Progressive brain atrophy was detected by structural MRI. First row: MRI on 15 February 2019; second row: MRI on 25 April 2021. (A,D) axial T1 weighted images; (B,E) axial T2 weighted images; (C,F) coronal FLAIR images. The patient showed atrophy in the left temporal lobe compared with the baseline.
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F1
A mildly widened lateral sulcus was observed, with the left more pronounced than the right (Figure 1). On 25 April 2021, another MRI examination was performed at the hospital (Figure 1).
11C-Pittsburgh compound B-Positron emission tomography imaging (PIB-PET) revealed the accumulation of Abeta in the prefrontal cortex, temporal lobe, posterior cingulate cortex, and parietal-occipital junction cortex.
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F2