PMC9427171_01
Radiological images. A An axial CT brain revealing a right hypodense CPA tumor (asterisk) that enhances following B contrast sequences, with C IAC enlargement. T2-weighted MR image demonstrating heterogeneous intensity lesions on D axial and E coronal sequence. F, G On the T1-weighted post gadolinium, a heterogenous enhancement is seen following gadolinium. H Day 1 postoperative axial CT brain showing resection cavity with partial relief of brain stem compression
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Fig1
There was a widening of the internal acoustic canal (IAC) (Fig. 1A-C). During a clinic visit, the brain magnetic resonance imaging (MRI) was reviewed, confirming a right IAC/CPA lesion, favoring benign VS and consistent with a new diagnosis of NF1 (Fig. 1D-G).
Hematoxylin-eosin stain. The tumor shows a biphasic appearance with A compact fibrillar area, and B loose microcystic area (x 10 magnification). C Rosenthal fibers (orange arrow) and eosinophilic granular bodies (red arrow) are present (x 20 magnification). D Immunohistochemical expression of positive glial fibrillary acidic protein (x 10 magnification)
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Fig2
These histopathological features were typical for pilocytic astrocytoma (Fig. 2).