PMC7067124_01
[18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography images of a 47-year-old woman with gestational trophoblastic neoplasia for preoperative staging found a small hypermetabolic lesion with modest enhancement on computed tomographyin the upper endometrial wall, but without the evidence of active metastasis. The [18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography study (a and c) revealed similar findings as [18F]-fluorocholine (b and d), but the magnitude of [18F]-fluorocholine accumulation was much lower than that of [18F]-2'-fluoro-2'-deoxy-D-glucose
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F1
PMC7067124_02
[18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography images of a 47-year-old woman with gestational trophoblastic neoplasia for preoperative staging found a small hypermetabolic lesion with modest enhancement on computed tomographyin the upper endometrial wall, but without the evidence of active metastasis. The [18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography study (a and c) revealed similar findings as [18F]-fluorocholine (b and d), but the magnitude of [18F]-fluorocholine accumulation was much lower than that of [18F]-2'-fluoro-2'-deoxy-D-glucose
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F1
Whole-body positron emission tomography/computed tomography images of a 52-year-old woman with recurrent gestational trophoblastic neoplasia, posttotal hysterectomy with bilateral salpingo-oophorectomy. No hypermetabolic lesions were detectable at the residual calcified mass after chemotherapy in either [18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography (a and b) or [18F]-fluorocholine positron emission tomography/computed tomography (c and d). Contrast material was not used due to severely impaired renal function
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F2
In contrast, all metastatic lesions in the lungs were hypermetabolic, especially with [18F]-FDG [Figures 2, 3 and Table 1].
Whole-body [18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography study (without contrast) in the same patient (Case 2) revealed multiple hypermetabolic pulmonary nodules in both lungs, suggestive of pulmonary metastases (a-c), which on the [18F]-fluorocholine positron emission tomography/noncontrast computed tomography study showed less uptake intensity in the corresponding lesions (d-f)
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In contrast, all metastatic lesions in the lungs were hypermetabolic, especially with [18F]-FDG [Figures 2, 3 and Table 1].
PMC7067124_03
[18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography images of a 47-year-old woman with gestational trophoblastic neoplasia for preoperative staging found a small hypermetabolic lesion with modest enhancement on computed tomographyin the upper endometrial wall, but without the evidence of active metastasis. The [18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography study (a and c) revealed similar findings as [18F]-fluorocholine (b and d), but the magnitude of [18F]-fluorocholine accumulation was much lower than that of [18F]-2'-fluoro-2'-deoxy-D-glucose
WJNM-19-72-g001.jpg
PMC7067124_03_WJNM-19-72-g001.jpg
F1
[18F]-2'-fluoro-2'-deoxy-D-glucose positron emission tomography/computed tomography images of a 36-year-old patient with choriocarcinoma and lung metastases, acquired 5 months postchemotherapy, revealed a hypermetabolic pulmonary nodule located in the left lower lobe, suggestive of pulmonary metastasis (a and c), which on the [18F]-fluorocholine positron emission tomography/computed tomography study showed similar but less uptake intensity (b and d). The surgical bed and regions elsewhere were unremarkable
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F4