PMC7295250_01
Proband with familial translocation inherited from the mother
JHRS-13-68-g001.jpg
PMC7295250_01_JHRS-13-68-g001.jpg
F1
The karyotype analysis of the proband revealed apparently balanced translocation involving short arm of one of the chromosome 2 and long arm of one of the chromosome 12, the breakpoints being p16 and q22, respectively [Figure 1].
Double two-way translocation in the mother of proband
JHRS-13-68-g002.jpg
PMC7295250_01_JHRS-13-68-g002.jpg
F2
The second translocation involved long arm of chromosome 4 and long arm of chromosome 16 [Figure 2].