PMC4772628_01
On the left, PET/CT from November 27, 2015 demonstrating RRx-001-induced central infarction of an abdominal metastasis. On the right, PET/CT from December 22, 2015 showing dramatic shrinkage of the lesion after one dose of cisplatin and pemetrexed, indicative of episensitization. The high FDG uptake in the discontinuous rind of the tumor may be secondary to invasion by inflammatory cells. Note the FDG-avid myocardium just above the tumor on the left.
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F3
In the 5th week of treatment, he was reimaged with PET/CT due to progressively worsening abdominal pain, which demonstrated a dramatically enlarged necrotic mass with a thin capsule of apparently viable tumor (fig. 3). These images are shown (fig. 3).