PMC8273695_01
Indirect immunofluorescence assay on HEp-2 cells shows the following pattern: Homogeneous nucleolar/AC-8 (titer 1,600). According to ANA pattern classification Chan et al..
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SSc ( Figure 1 ). Specific autoantibodies were tested as the next step.
Peripheral subpleural ground-glass opacities compatible with early stage of interstitial lung disease (arrow) are present in the anterior and basal segments of the right middle lobe as well as along the oblique (major) fissure, and on the left side within the lingular segment.
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On the 11th of March HCRT showed ground glass opacities with predominantly peripheral and subpleural distribution such as in the early stages of interstitial lung disease (ILD) ( Figure 2 ).