PMC3934455_01
Chest X-ray shows chest soft tissue calcification (arrow heads) and calcification along the left upper arm blood vessels (arrows).
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However, daily chest X-rays demonstrated progressive nonspecific calcification of the chest soft tissue and the vessels of both arms (Figure 1).
(a) A cut section of the heart demonstrates significant increase in cardiac wall thickness. ((b), (c)) Microscopic section of the heart shows myocardium with extensive calcium deposition (b) and fibrosis (c) with no evidence of inflammation (hematoxylin-eosin, original magnification x200 [(b), (c)]).
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Cardiovascular dissection revealed increased biventricular wall thickness (Figure 2(a)) with evidence of gross arterial calcification along the large vessels. However, inflammation suggestive of myocarditis could not be identified (Figures 2(b) and 2(c)).
Microscopic picture from the left coronary artery focally demonstrates calcification of the internal elastic lamina (hematoxylin-eosin, original magnification x200).
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The coronary arteries demonstrated focal calcification of the internal elastic lamina (Figure 3), while sections from the ascending and descending aorta exhibited extensive calcification with disruption of the elastic lamina and intimal fibrosis (Figure 4).
Microscopic picture from the ascending aorta shows extensive calcification with disruption of the elastic lamina and intimal fibrosis (hematoxylin-eosin, original magnification x200).
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The coronary arteries demonstrated focal calcification of the internal elastic lamina (Figure 3), while sections from the ascending and descending aorta exhibited extensive calcification with disruption of the elastic lamina and intimal fibrosis (Figure 4).
Microscopic picture from the renal hilum shows extensive calcium deposition involving internal elastic lamina with ingrowth of loose fibromyxoid tissue resulting in luminal narrowing and obstruction (hematoxylin-eosin, original magnification x200).
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The renal hilar vessels were extensively involved (Figure 5).