PMC9773417_01
Pre-treatment skin images of (A) anterior skin lesions (B) posterior skin lesions (C) anterior lower extremities (D) posterior lower extremities.
fmed-09-1072039-g001.jpg
PMC9773417_01_fmed-09-1072039-g001.jpg
F1
The patient reported erythema of the forearms and trunk with dense, large military pustules, with areas of desquamation (Figure 1).
(A) Skin biopsy of the left lower limb with hematoxylin-eosin staining at 50x magnification. Squamous epithelial hyperplasia was observed with epidermal pustular formations. Kogoj abscesses can be seen at the pustular margin. The upper dermis showed lymphocytic infiltration and some dermal papillary edema. Perivascular infiltration and a small number of lymphocytes were also observed. (B) Skin biopsy of the left lumbar region with hematoxylin and eosin staining at 100x magnification. Squamous epithelial hyperplasia, Munro micro abscesses, and Kogoj abscesses were observed in the epidermis. A small amount of lymphocytic and neutrophilic infiltrate was observed in the upper dermis. Some dermal papillary edema, vascular dilation hyperemia and lymphocytic perivascular infiltration was also observed.
fmed-09-1072039-g002.jpg
PMC9773417_01_fmed-09-1072039-g002.jpg
F2
Lymphocytic and neutrophilic infiltrate was also present in the superficial dermis (Figure 2).
Post-treatment skin images of (A) anterior skin lesions (B) posterior skin lesions (C) anterior lower extremities (D) posterior lower extremities.
fmed-09-1072039-g003.jpg
PMC9773417_01_fmed-09-1072039-g003.jpg
F3
Within 72 h, the erythema, pain, scales, and pustules were significantly relieved, and the patient's mental state was improved (Figure 3).