PMC5598549_01
Overall pattern of an increasing total daily dose of voriconazole (red line) to maintain a safe and effective plasma level of voriconazole (blue diamonds).. Note: The graph shows the variation in the total daily dose and the trough plasma level of voriconazole.
dhps-9-089Fig1.jpg
PMC5598549_01_dhps-9-089Fig1.jpg
f1-dhps-9-089
Dose increases were made several times as shown in Figure 1.