PMC6501230_01
(a) Pretreatment scans (MRI). Axial T2 WI (A) and postcontrast (Eovist) Axial T1 WI (B) showing a 7 cm mass in the right liver lobe (arrows) and multiple smaller lesions in both liver lobes. (b) Posttreatment scans (MRI). Axial T2 WI (A) and postcontrast (Eovist) Axial T1 WI (B) show the decrease in size of the largest mass in the right liver lobe (arrows).
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fig1
April 2016, the patient started a combination of ipilimumab (3 mg/kg) and nivolumab (1 mg/kg) administered every 3 weeks. After three cycles of treatment, imaging revealed the same number of hypodense lesions; the largest lesion measured 5.5 x 3.4 cm (Figure 1).
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(a) Pretreatment scan (8/22/2016) (MRI). Axial T2 WI (A) and postcontrast (Eovist) Axial T1 WI (B) showing an 11 cm mass in the left liver lobe (arrows) and multiple smaller lesions in both liver lobes. (b) Ongoing treatment (5/2/2018) (MRI). Axial T2 WI (A) and postcontrast (Eovist) Axial T1 WI (B) show the decrease in size of the largest mass in the left liver lobe (arrows) now measuring 4.8 cm with no enhancement. There is a decrease in size and number of the multiple smaller lesions in both liver lobes.
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fig2
A repeated abdominal magnetic resonance imaging (MRI) in November 2016 showed a marked decrease in the size and number of metastatic liver lesions (Figure 2).
PMC6501230_06
(a) Pretreatment scans (MRI). Axial T2 WI (A, B) and postcontrast (Eovist) Axial T1 WI (C) show multiple metastatic lesions (arrows) in both liver lobes. (b) Posttreatment scans (MRI). Axial T2 WI (A, B) and postcontrast (Eovist) Axial T1 WI (C) show the decrease in size and number of multiple lesions (arrows) in both liver lobes.
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fig3
Repeated imaging in June 2017 showed a decrease in the size of the metastatic hepatic lesion, from 2.2 x 2.1 to 1.7 x 1.5 cm (Figure 3).
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