PMC6279913_01
STIR (A) and T2-weighted images (B,C) demonstrating edema ( ) in the anterior and posterior calves of the patient. (A) Increased STIR image signaling in the gastrocnemius with unsymmetrical involvement. (B) Increased intramuscular T2 image signaling within the anterior tibial muscle at the sagittal section. (C) Patchy T2-weighted hyperintense area in the gastrocnemius, soleus, and anterior tibial muscles.
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F1
T2 and STIR imaging (Figure 1). The biopsied muscle from the right quadriceps had widespread myofiber necrosis and regeneration without prominent inflammatory cell infiltration around and within the myofibers (Figure 2).
Histologic features of the patient's quadriceps femoris. The hematoxylin and eosin-stained frozen section demonstrated necrotic fibers ( ), regenerating myofibers ( ), atrophic myofibers, and unusual vacuoles in some degenerated myofibers without prominent lymphocytic infiltrates (A). MHC I was upregulated in some myofibers (B), but there was no prominent accumulation of C5b9 in the myofibers (C). CD4, CD8, and CD68 antibodies did not obviously positively stain the infiltrates (D-F, respectively). Scale bars: 100 mum (A-F) and 50 mum (C).
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F2
T2 and STIR imaging (Figure 1). The biopsied muscle from the right quadriceps had widespread myofiber necrosis and regeneration without prominent inflammatory cell infiltration around and within the myofibers (Figure 2).
PMC6279913_02