PMC6131849_01
Initial electrocardiogram showing a sinus rhythm with a prolonged QTc interval of 503 ms. The tangent method was used in order to define the end of the T-wave
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Fig1
Electrocardiography (ECG) showed a sinus rhythm of 61 beats per minute with a prolonged corrected QT interval (QTc) of 503 ms as shown in Fig. 1.
Telemetry records showing Torsades de Pointes
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Fig2
Fig. 2. Two grams of magnesium sulphate was administered intravenously, after which sinus rhythm was restored. Four hours later, she had complete loss of circulation, after which cardiopulmonary resuscitation was initiated according to protocol.
a Showing serum drug serum levels of fluoxetine(black triangles), norfluoxetine (black circles), and the combined serum concentrations of both fluoxetine and norfluoxetine (black squares). b Showing drug serum levels of risperidone (black triangles), 9-OH-risperidone (black circles), and the combined concentrations of both risperidone and 9-OH-risperidone (black squares). The yellow striped line indicates the onset of TdP
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Fig3
Serum levels of fluoxetine and risperidone and their metabolites were measured in retrospect, as shown in Table 1 and Fig. 3a, b.
Showing the course of QTc interval duration during hospital admission
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Fig4
Subsequent ECGs showed progressive prolongation of the QTc interval up to 565 ms, as shown in Fig. 4.