PMC5274686_01
Serial brain magnetic resonance imaging (MRI). Consecutive fluid attenuated inversion recovery sequences (FLAIR) of brain MRIs of the patient with super refractory status epilepticus in a medically induced coma. The serial images show development and progression of diffuse cerebral atrophy.
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fig1
Prior epilepsy workup (including FISH, SNP array, and MECP2 sequencing) was unremarkable as well as a magnetic resonance imaging (MRI) of the brain 5 years prior to current admission (Figure 1(a)). Over the course of hospitalization, he had serial MRI brains performed, including an admission MRI at our institution (11 days from onset; Figure 1(b)). Diffuse generalized atrophy was noted in comparison to prior MRI (Figure 1(a)). The diffuse cerebral atrophy significantly progressed by 31 days and 136 days from onset of status epilepticus (Figures 1(c) and 1(d), resp.).