PMC5415662_01
Abdominal CT scan with enhanced mass at the neck of pancreas (arrow).
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fig1
CT scan with intravenous and oral contrast was done. CT scan revealed 7.6 x 13 mm solitary and enhancing lesion at the neck of pancreas in favour of insulinoma (Figures 1 and 2).
Abdominal CT scan (coronal view) shows intrapancreatic tumor (arrow).
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fig2
CT scan with intravenous and oral contrast was done. CT scan revealed 7.6 x 13 mm solitary and enhancing lesion at the neck of pancreas in favour of insulinoma (Figures 1 and 2).
Pancreatic endocrine tumor with nests of uniform cells surrounded by a fibrovascular stroma.
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fig3
With clinical diagnosis of pancreatic insulinoma, the patient underwent open subtotal pancreatectomy; pathologic examination of specimen with complementary immune histochemical (IHC) staining confirmed insulinoma as the final diagnosis (Figures 3-5).
Nuclear features show coarsely clumped, "salt and pepper" chromatin pattern.
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fig4
With clinical diagnosis of pancreatic insulinoma, the patient underwent open subtotal pancreatectomy; pathologic examination of specimen with complementary immune histochemical (IHC) staining confirmed insulinoma as the final diagnosis (Figures 3-5).
IHC for chromogranin (one of the endocrine differentiation markers) expressed by tumor cells.
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fig5
With clinical diagnosis of pancreatic insulinoma, the patient underwent open subtotal pancreatectomy; pathologic examination of specimen with complementary immune histochemical (IHC) staining confirmed insulinoma as the final diagnosis (Figures 3-5).