PMC3874322_01
Representative endoscopy images. 1A: stomach in retroflexion, showing granular, erythematous and friable mucosa (case 4). 1B: 2nd portion duodenum, showing erythematous, edematous mucosa with superficial ulceration (case 1). 1C: distal ileum, demonstrating continuous extensive superficial ulcers and spontaneous bleeding (case 4). 1D: pouch with erythematous mucosa and decreased vascular pattern (case 1).
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F1
On admission, an upper endoscopy and ileoscopy showed diffuse erythematous and edematous mucosa of the stomach, duodenum and ileum (Figure 1).
PMC3874322_02
Representative endoscopy images. 1A: stomach in retroflexion, showing granular, erythematous and friable mucosa (case 4). 1B: 2nd portion duodenum, showing erythematous, edematous mucosa with superficial ulceration (case 1). 1C: distal ileum, demonstrating continuous extensive superficial ulcers and spontaneous bleeding (case 4). 1D: pouch with erythematous mucosa and decreased vascular pattern (case 1).
nihms537625f1d.jpg
PMC3874322_04_nihms537625f1d.jpg
F1
On admission, an upper endoscopy and ileoscopy showed diffuse erythematous and edematous mucosa of the stomach, duodenum and ileum (Figure 1).
Representative histology sections of the duodenum (A) and pouch (B) from case 2. The findings in both the duodenal and pouch biopsies are nearly identical and show very dense lamina propria inflammatory cell infiltrates, including a very prominent component of plasma cells as well as large clusters of neutrophils. The duodenal biopsies exhibit moderate villous blunting as well.
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F3
Pathology showed dense mixed cell infiltrates in the lamina propria, including a prominent component of plasma cells and clusters of neutrophils in all biopsies (Figure 3).
PMC3874322_03
PMC3874322_04
Representative endoscopy images. 1A: stomach in retroflexion, showing granular, erythematous and friable mucosa (case 4). 1B: 2nd portion duodenum, showing erythematous, edematous mucosa with superficial ulceration (case 1). 1C: distal ileum, demonstrating continuous extensive superficial ulcers and spontaneous bleeding (case 4). 1D: pouch with erythematous mucosa and decreased vascular pattern (case 1).
nihms537625f1d.jpg
PMC3874322_04_nihms537625f1d.jpg
F1
On admission, an upper endoscopy and ileoscopy showed diffuse erythematous and edematous mucosa of the stomach, duodenum and ileum (Figure 1).
Representative images of the jejunum (A) and ileum (B) during videocapsule endoscopy in case 4. The images show erythematous and edematous mucosa with superficial ulceration.
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F2
A video capsule endoscopy showed scattered erythematous lesions and ulcerations throughout the visualized duodenum, jejunum and ileum (Figure 2).
PMC3874322_05