PMC8382546_01
Biochemical and radiological follow-up. (a) TSH and FT4 values during levothyroxine treatment titration. (b) Reduction of the pituitary mass size during levothyroxine treatment, in a follow-up of around 5 years.
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In the meanwhile, we started treatment with levothyroxine at 12.5 microg/kg/day and thyroid function was evaluated approximately every 40 days to titrate the dosage (Figure 1(a)). At this time, a first reduction of the pituitary enlargement was registered at MRI follow-up (Figure 1(b)).