PMC10084221_01
Clinical features during UVA1-LED treatment. The patient was initially irradiated with 60 J/ cm2 of UVA1-LED once or twice per week, and the dose was increased to 90 J/cm2. The erythema was observed to "escape" outside the irradiation field with a wood grain pattern (A) Numbers indicate total cumulative irradiations. The irradiation frequency was increased to 3 times per week, which successfully ameliorated the erythema on the left thigh (A) and decreased the concentration of soluble interleukin 2 receptors (B)
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The erythema was observed to "escape" the irradiation field, and thus the irradiation frequency was increased to 3 times per week, which led to amelioration of the erythema on the left thigh and a concomitant decrease in the concentration of soluble interleukin 2 receptors (sIL-2R) (Figure 1). Periodic photography shows the change in the extent of the erythema throughout therapy (Figure 1).