PMC5962713_01
Changes in brain and spinal cord MRI. MRI 2010 (A-C). Axial T2 FSE MRI image of the brain (A) demonstrates multiple periventricular lesions in the lateral ventricles (black arrows) and scarce thalamic lesions (*). Axial proton-density-weighted MRI image (B) shows predominant infratentorial lesions (white arrow in pons and black arrow in right middle cerebellar peduncle). Sagittal STIR and T2 FSE MRI images of the spinal cord (C) highlight the presence of a short segment spinal cord lesion (white arrow in C2). MRI 2016 (D-F). Axial T2 FSE MRI image (D) shows increased in the number of thalamic lesions (* and white arrows) and stability of the periventricular lesions (black arrows). Axial proton-density-weighted MRI image (E) shows stability of the infratentorial lesions respect to 2010 (arrows). Sagittal STIR and T2 FSE MRI images of cervical spinal cord (F) demonstrate new short segment lesions affecting C3 and C7 levels respect (black arrows).
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F1
Brain and spinal cord MRI (FLAIR, TSE T2 sequence, PD, and T1 post gadolinium) was performed (Table 1; Figure 1).
Timeline of clinical course and treatment.
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F2
A diagram of the clinical course and administered treatments is displayed as Figure 2.