PMC9715335_01
Platelet count at baseline (2 months before), since the last interferon beta-1a injection before the occurrence of petechial lesions (IFNbeta-1a, D0) and upon rechallenge (D14), and their evolution with subsequent treatments. Prednisone (PDN) is only shown when 1 mg/kg has been initiated. Two administrations of intravenous immunoglobulins (IVIG, 2 g/kg total dose) were performed.
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fig1
The last IFNbeta-1a injection was three days before the onset of symptoms (Figure 1, D0, platelet count 152 G/L). After 24 hours, the platelet count rose to 57 G/L (Figure 1) and progressive platelet normalization allowed the patient to be discharged after six days.