PMC10288839_01
Changes in the clinical appearance of the right eye in slit-lamp microscopy. (A) Appearance of the patient's right eye at initial diagnosis. (B) Appearance of the patient's right eye after SO removal and adequate intraocular and anterior chamber lavage. (C) Appearance of the right eye 2 months after the first-stage surgery. (D) Appearance of the right eye after epithelial lesion excision combined with amniotic membrane transplantation 3 months after the first-stage surgery was completed. (E) Appearance of the right eye 2 months after the second-stage surgery.
fmed-10-1147767-g0001.jpg
PMC10288839_01_fmed-10-1147767-g0001.jpg
F1
Extensive corneal leukoplakia, mild limbus neovascularization, and aphakia were found (Figure 1A) using slit-lamp microscopy. The corneal leukoplakia had faded slightly (Figures 1B, C, 2B, C) at the 2-month follow-up. Epithelial lesion excision combined with amniotic membrane transplantation (Figure 1D) was performed 3 months after the first-stage surgery. A significantly clearer cornea (Figures 1E, 2D) was observed at the next 2-month follow-up.
Changes in the appearance of the cornea measured using AS-OCT. (A) Appearance of the patient's right eye at initial diagnosis, with an eccentric thickness of the subepithelium (maximum thickness of cornea: 1.42 mm) and normal thickness of the stroma (0.49 mm). (B) Appearance of the patient's right eye 2 days after SO removal and adequate intraocular and anterior chamber lavage, with a smaller thickness of the cornea (0.96 mm). (C) Appearance of the right eye 2 months after the first-stage surgery, with a further decrease in the thickness of the cornea (0.92 mm). (D) Appearance of the right eye 2 months after second-stage surgery, with normal thickness of the cornea (0.55 mm). The lens capsular bag is visible.
fmed-10-1147767-g0002.jpg
PMC10288839_01_fmed-10-1147767-g0002.jpg
F2
Anterior segment optical coherence tomography (AS-OCT) further revealed a marked eccentric thickening of the subepithelium and normal thickness of the stroma (Figure 2A), inconsistent with previous silicone oil keratopathy cases of bullous keratopathy or BSK. The corneal leukoplakia had faded slightly (Figures 1B, C, 2B, C) at the 2-month follow-up. A significantly clearer cornea (Figures 1E, 2D) was observed at the next 2-month follow-up.