PMC9837076_01
Preoperative abdominal computed tomography scan showing a 3.4 x 3.0-cm heterogeneously enhancing right adrenal mass.
gr1.jpg
PMC9837076_01_gr1.jpg
fig1
Imaging showed a heterogeneous enhancing right adrenal mass measuring 3.4 x 3.0 cm and 37, 104, and 57 HU at the precontrast, venous, and delayed phases, respectively (Fig. 1).
Pathology. A, The gross cut surface of the tumor. B, Hematoxylin and eosin stain demonstrating intermixed chromaffin (large basophilic cells with large nuclei) and adrenocortical adenoma cells (eosinophilic cytoplasm with small rounded nuclei). C, Ganglioneuroma component. D, Chromogranin stain highlighting pheochromocytoma cells. E, Inhibin stain highlighting adrenocortical adenoma cells. F, Focal adrenocorticotropic hormone staining in pheochromocytoma cells. All micrographs at x200 magnification.
gr2.jpg
PMC9837076_01_gr2.jpg
fig2
The mass focally extended through the cortex into the surrounding adipose tissue (Fig. 2 A, arrow). Microscopically, the tumor was characterized by a mixture of pheochromocytoma and adrenocortical adenoma components creating a composite tumor having both cortical and medullary characteristics (Fig. 2 A through F).