PMC6701427_01
PMC6701427_02
Clinical aspect of the mass located in the right sublingual region (tip of the tongue turned to the left side). The superior limit is above the occlusal surface of the molars.
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fig1
Physical examination revealed a tender mass, in the right sublingual region, though its posterior limit could not be clearly defined (Figure 1).
RMI features of the lesion: both T1- (a) and T2- (b) weighed images show hypersignal.
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fig2
T1 and T2 hypersignals (Figure 2); the conclusion was that the sublingual mass could be a ranula. The patient was proposed an excision, and the procedure was performed under local anesthesia.
Resection specimen: 37 x 32 mm encapsulated yellow mass.
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fig3
Histology showing mature adipocytes, uniform spindle cells, and short bundles of collagen in a myxoid matrix (HE staining, x20).
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fig4
Immunohistochemical anti-PS100 staining (x20): adipocytes are PS100 positive.
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fig5
Spindle cells were immunoreactive for CD34 and negative for PS100 (Figures 5 and 6).
Immunohistochemical anti-CD34 staining (x20): adipocytes are CD34 negative and spindle cells are CD34 positive.
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fig6
Spindle cells were immunoreactive for CD34 and negative for PS100 (Figures 5 and 6).