PMC9112167_01
Painful erythematous papules studded with white blisters on the patient's left face (A) and right axillary skin (B).
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The physical examination after admission revealed a body temperature of 38 C; the presence of painful erythematous papules studded with white blisters on her palms, back of the hands, fingers, face and limbs (Figure 1); bilateral axillary and inguinal lymphadenopathy; and moist rales in the bilateral lungs.
Histopathology examination of a skin lesion showing dense infiltrates throughout the dermis (hematoxylin-eosin, original magnification x100; original magnification x200) (A and B). The infiltrate was predominantly composed of neutrophils (hematoxylin-eosin staining, original magnification x 400) (C).
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Histopathology of the rashes and the lymph node biopsy specimen obtained from the patient confirmed SS (Figure 2).
CT findings. 2016-3 chest CT showed multiple patchy exudations, fibrous proliferation and ground glass opacity in both lungs, bronchiectasis in the dorsal segment of the left lower lobe and pleural thickening (A). 2016-3 bone CT showed irregular bone destruction of the lower border of the C7 vertebral body, the upper border of the T1 vertebral body and its spinous process, bone defect of the anterior border of the T1 vertebral body, with surrounding abscess and the narrowing of the C7-T1 intervertebral space (arrows) (B-D). 2017-7 chest CT showed absorption of pulmonary lesions after anti-NTM therapy (E). 2017-7 bone CT shows the repair of bone destruction in C7-T1 vertebral bodies and the disappearance of the surrounding abscess after anti-NTM therapy (arrows) (F-H).
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Corp, Wuhan, China), and the AIGA titer was 79276.59 ng/mL (the cutoff value of the AIGA titers was 9583.21 ng/mL). Chest CT showed increased pulmonary lesions with multiple patchy exudations, fibrous proliferation and ground glass opacity in both lungs and bronchiectasis in the dorsal segment of the left lower lobe (Figure 3A). Bone CT revealed bony destruction in C7-T2 vertebral bodies with surrounding abscess formation (Figure 3B-D). In July 2017, repeated chest CT showed that the pulmonary lesions were absorbed (Figure 3E). Repeated bone CT showed that the bone destruction had further repaired, and the surrounding abscess had disappeared (Figure 3F-H).