PMC8504686_01
Patient of an 80-year-old with pure mucinous carcinoma of the left breast. mammogram images ((a) face view and (b) profile view): Well circumscribed and lobulated mass.
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The radiologist's conclusion was a suspicious finding (ACR 4A) (Figure 1).
(a and b) HE 20x magnification: nests of tumor cells floating in large lakes of extracellular mucin. (c and d) HE 40x magnification: malignant cells presented mild to moderate nuclear atypia with rare mitotic figures.
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Mitotic figures were rare, with 4 mitotic figures per 10 high power fields (40x) (Figure 2).
Immunohistochemistry 10x magnification: the neoplastic cells were strongly positive for ER (a), PR (b), without superexpression of HER2/neu (c), and a week proliferation index evaluated by Ki-67 (d).
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The neoplastic cells were strongly positive for ER, PR, without superexpression of HER-2/neu, and a weak proliferation index evaluated by Ki-67 (Figure 3).