PMC5131232_01
Clinical intraoral presentation at time of the first appointment.
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fig1
Extent of bone destruction seen on CT scans ((a) CT, axial view; (b) CT, coronal view).
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fig2
Computed tomography scan revealed a solid tumor mass on the floor of the nasal cavity, measuring 5.6 x 5.2 x 5.2 cm, leading to erosion of the hard palate and of the medial wall of the maxillary sinus, bilaterally (Figure 2).
Microscopic examination revealed a plasma cell tumor. The histological sections showed lymphoid origin of tumor fragment characterized by the proliferation of atypical plasma cells which are arranged in sheets (a, HE); immunohistochemical reactions were positive for plasm cell (b); negative for kappa (c); and positive for lambda (d).
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fig3
Microscopic analysis revealed a neoplasm of well-differentiated plasma cells, with restriction of the lambda light-chain (Figure 3). IHC showed positivity for CD20, CD3, kappa, and lambda (Figure 3).
Clinical presentation at time of tumor staging ((a) fontal view; (b) coronal view; (c) intraoral view).
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fig4
Clinical intraoral presentation after two months of chemo-radiotherapy treatment.
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fig5
When examined 3 months later, the nasal obstruction was relieved completely and no residual tumor was observed (Figure 5).