PMC9976640_01
A: Upper right of image demonstrates tumor and lower left shows extensive inflammation. B: Demonstrating a higher magnification of the image in pane A, showing malignant features of non-small cell carcinoma; large pleomorphic cells with prominent nucleoli are seen. A large mitotic figure is shown (black arrow). C: Thyroid transcription factor-1 (TTF-1) immunohistochemical stain for lung adenocarcinoma, staining nuclei. D: Cytokeratin 7 (CK7) immunohistochemical stain for lung adenocarcinoma, staining cytoplasm.
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FIG1
The patient was found to have a right lung mass on a CT chest, and 52 days later a CT-guided needle core biopsy diagnosed poorly differentiated, invasive lung adenocarcinoma with extensive necrosis (Figure 1).
A: Chest film from 363 days prior to hospital admission. B: Hospital chest film showing a large superior segment right lower lobe mass (red arrow).
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FIG2
Compared to a negative chest film from 1 year prior (Figure 2A), a hospital chest film showed a right lower lobe mass (Figure 2B).
A: CT chest from 132 days prior to hospital admission CT chest (seen in pane B), demonstrating a right lower lobe lung mass (red arrow). B: CT chest obtained on day 9 of hospital admission demonstrating a larger right lower lobe lung mass (red arrow).
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PMC9976640_01_cureus-0015-00000034386-i03.jpg
FIG3
Compared to a CT chest (Figure 3A) from 132 days prior (showing a 5.1 x 4.7 x 1.3 cm mass), a new CT chest (Figure 3B) showed a mass measuring 6.9 x 6.2 x 1.9 cm in the right lower lobe with new occlusion of bronchi and pulmonary vessels to the region of the mass.