PMC9897908_01
SC at low power (4x magnification) shows a large multinodular tumor invading the dermis with diffuse overlying ulceration present.
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fig1
A deep shave biopsy of the lesion revealed nearly complete epidermal ulceration with replacement by an in-situ and diffusely infiltrative, atypical-appearing clear cell tumor (Figure 1).
SC at high power (20x magnification) shows marked cytologic atypia, abundant clear-staining cytoplasm, and numerous mitotic figures.
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fig2
Large irregular nests and lobules of atypical-appearing clear cells with abundant multivacuolated cytoplasm, nuclear indentations, and vesicular to hyperchromatic-staining nuclei made up the majority of the tumor (Figure 2).
SC with lymphatic invasion.
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fig3
Lymphovascular invasion was also present, involving multiple small vessels (Figure 3).