PMC10070336_01
The touch prep showed loose clusters of cells with occasional vague acinar formations (a and b), abundant cytoplasm, occasional nucleoli, and mild-to-moderate anisonucleosis (c).
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F1
Touch prep of the needle cores performed for rapid onsite evaluation [Figure 1].
The core biopsy showed nests of cells with only mild nuclear anisocytosis and occasional inconspicuous nucleoli.
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F2
H&E stained sections are prepared from the tissue cores [Figure 2] and show a solid, cellular neoplasm.
(a) Trypsin, (b) Bcl-10, (c) PAS-D, (d) Synaptophysin, (e) Beta-catenin, and (f) CD-10.
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F3
Special stains and immunohistochemical preparations show the following results: Positive trypsin, BCL-10, and beta-catenin (membranous) with weak and focal positivity for neuroendocrine markers (synaptophysin, chromogranin, and CD56), PAS-D highlighted intracytoplasmic zymogen granules, and CD10 was negative [Figure 3].