PMC7476696_01
Clinical pictures of the patient with swelling over the arm.
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F1
A 39-year-old lady presented to our facility with a 20-year history of the right arm swelling which only progressively increased in size, to involve the entire arm, in the past 3 months (Fig. 1).
Radiograph of both humerus anteroposterior views shows significant marrow expansion with multiple lytic lesions containing ground-glass matrix seen affecting the involved bones in almost their entirety with the areas of overlying cortical break.
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F2
Radiological studies showed extensive lucent, ill-identified, "ground-glass" appearing lesions involving the entire right humerus (Fig. 2 and 3).
Magnetic resonance imagingof the right arm T2W coronal and T1W axial images showing extensive marrow infiltration of a diffusely T1 isointense and T2W hypointense lesion with few areas of hyperintense foci within involving the humerus and part of the scapula.
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F3
Radiological studies showed extensive lucent, ill-identified, "ground-glass" appearing lesions involving the entire right humerus (Fig. 2 and 3).
Microscopy of the lesion showing multiple sections examined showed a low to moderately cellular lesion composed of short spindle cells arranged in a patternless pattern with irregular trabeculae of woven bone giving "Chinese letter pattern" appearance.
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F4
These features were concluded to be consistent with a fibrous-osseous lesion (Fig. 4).
Forequarter amputation specimen.
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F5
X-ray after forequarter amputation.
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F6
Computed tomography thorax showing stable lung nodule.
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F7