PMC3804819_01
PMC3804819_02
A) Sheets of cells with reticular growth pattern and a more compact adenoid cystic morphology (Hematoxylin & Eosin stain, Zeiss Axioshop 40, magnificationx100). B) Sickled erythrocytes (Hematoxylin & Eosin stain, Zeiss Axioshop 40, magnificationx400).
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Subsequently, a renal biopsy was performed and demonstrated a renal medullary carcinoma (Figure 1).
A) Paraaortic lymphadenopathy, patient case #2. B) Response after platin-based chemotherapy. C) Mediastinal lymphadenopathy, patient case #2. D) Response after platin-based chemotherapy.
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The patient initially had clinical and radiological partial response (Figure 2), however had disease progression after six cycles of chemotherapy.
PMC3804819_03
A) Lung metastasis, patient case #3. B) Response after platin-based chemotherapy. C) Mediastinal lymphadenopathy, patient case #3. D) Response after platin-based chemotherapy.
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Initial clinical and radiological response was observed (Figure 3), however she experienced disease progression after the fifth cycle and died five months after beginning chemotherapy.
PMC3804819_04
PMC3804819_05