PMC5943133_01
A pituitary tumor of 4.3 x 4.1 x 3.0 cm in the sella involving cavernous sinuses and extending inferior to the sphenoid sinus and third ventricle.
medi-97-e9546-g001.jpg
PMC5943133_01_medi-97-e9546-g001.jpg
F1
Magnetic resonance imaging (MRI) of the sella region was therefore performed, revealing a pituitary tumor measuring 4.3 x 4.1 x 3.0 cm in the sella, involving cavernous sinuses and extending inferior to the sphenoid sinus and third ventricle (Fig. 1).
Histopathological findings: Hematoxylin and eosin staining for the cells in the surgical specimen showed diffuse proliferations of small atypical cells (A, x200). Immunostaining for thyroid-stimulating hormone reveals the expression of TSHb (B, x200), and the adenoma shows diffuse staining for antibody against prolactin (C, x200).
medi-97-e9546-g003.jpg
PMC5943133_01_medi-97-e9546-g003.jpg
F2
Upon immunohistochemical examination, the resected pituitary adenoma cells exhibited positive staining with the TSH and PRL antibody, and the percentage of positive Ki-67 was <2%, suggesting that the tumor was benign (Fig. 2).