PMC4069812_01
Brain Scans and Imaging.. In 2009, a perfusional 99mTc-ECD-SPECT brain scan of the patient revealed bilateral hypoperfusion of the visual association cortices (arrows) (A). Brain magnetic resonance imaging revealed hyperintensities of the optical radiations and bilateral parieto-occipital atrophy (B). In 2012, 99mTc-ECD-SPECT revealed an area of perfusional deficit within the post-central right lobule (arrow) (C). MRI revealed atrophy of the post-central parietal lobule (thick arrow) and increased and asymmetric dilatation of the posterior horn of the right lateral ventricle (small arrow) (D).
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An assessment of brain perfusion with 99mTc-ECD (Ethyl Cysteinate Diolef)-SPECT revealed complete obscuration of the visual association areas within both occipital regions (Figure 1A,B). MRI at that time revealed increased atrophy of the right post-central parietal lobule with enlargement of the posterior horn of the right lateral ventricle, and an overwhelming absence of perfusion of brain 99mTc-ECD-SPECT within that area (Figure 1C,D).