PMC7501416_01
Visualization of implanted electrodes and stimulation targets. A) Sagittal and B) axial views with 3D rendering of stimulated targets. C) Coronal and D) axial plane images of the coregistered implant, with color coded stimulation targets. Red: anterior thalamus; yellow: insula; green: frontal and central operculum; blue: inferior frontal gyrus pars opercularis. Images are show in neurological orientation (right sided structures located to the right). Images were generated using Lead-DBS software and thalamic and cortical deformable atlases.
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A fourth 3387 lead was implanted in the right anterior nucleus of the thalamus (ANT) (Fig. 1).
Four electrodes were permanently implanted for chronic subthreshold stimulation. Three leads targeted the right frontal head region, and one lead targeted the right anterior nucleus of the thalamus. Continuous stimulation was started in the right frontal leads at 2 Hz. After five months of stimulation the patient reported seizure freedom. Two months later stimulation of all leads ceased.
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No stimulation was started for the right ANT lead (Fig. 2).