PMC6925780_01
CT demonstrating ascites and mildly nodular liver surface contour (oral and IV contrast present).
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Then, at the nine-year mark from her original breast cancer (2/2019), a routine follow-up CT scan (Figure 1) revealed a mildly nodular liver surface contour suggestive of cirrhotic changes, but no focal hepatic lesion.
MRI demonstrating course texture (VIBE axial image post gadolinium).
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She next had gadolinium-enhanced magnetic resonance imaging (MRI) of the liver (Figure 2), which demonstrated a nodular liver surface contour and a fibrotic appearance of the hepatic parenchyma.
Diffusely infiltrating nests of intermediate-grade ductal adenocarcinoma with disrupted hepatic parenchyma (H&E) ((a) 100x and (b) 400x). Tumor cell nests staining for estrogen (c) and progesterone (d) receptors.
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Immunohistochemical stains for estrogen receptor and progesterone receptor demonstrated positivity in 100% and 90% of tumor cells, respectively (Figure 3).