PMC6369462_01
Low power (2x) view of the entire biopsy demonstrating a classic plate-like proliferation of keratinocytes parallel to the epidermis (a). Higher power (10x) of another section of the tumor shows the presence of numerous keratocysts (b) and a net-like architecture with frequent connections of the plate to the above epidermis (c).
CRIPA2019-4606493.001.jpg
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fig1
A biopsy was performed and histopathologic examination showed an overall well circumscribed lesion (Figure 1) with a subepidermal, horizontally oriented, plate-like proliferation of pale appearing squamous epithelial cells, with numerous points of connection with the overlying epidermis and peripheral palisading (Figure 1).
Higher power (20x) shows a keratocyst with no visible granular layer and abrupt keratinization (a). The pale pink cytoplasm of tumor cells is evidence of tumor glycogenation and the characteristic differentiation (b).
CRIPA2019-4606493.002.jpg
PMC6369462_01_CRIPA2019-4606493.002.jpg
fig2
Numerous keratocysts are noted at the base, while, notably, no visible granular layer is present (Figure 2).