PMC4899661_01
Patient phenotype. a The patient (left) and her mother (right). b Note the redundant, sagging and inelastic appearance of the skin of the patient.
cde-0008-0042-g01.jpg
PMC4899661_01_cde-0008-0042-g01.jpg
F1
Face, neck, breast and upper arms were the most affected areas (fig. 1), whereas the lower extremities were clinically completely unaffected.