PMC3861609_01
(A) Hematoxylin and eosin staining of the tumor cells in the rectum, lung and tonsil. (B) Immunohistochemical staining of the lung showed CDX-2(+), muc-1(+), CK7(+) and TTF-1(-) in the tumor cells. Immunohistochemical staining of the tonsil showed CDX-2(-), CK20(+), CK7(-) and TTF-1(-) in the tumor cells, confirming metastasis from colorectal adenocarcinoma (magnification, x400). CDX-2, caudal type homeobox transcription factor 2; muc-1, mucin-1; CK7, cytokeratin 7; TTF-1, thyroid transcription factor-1.
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The tumor was diagnosed as invading the visceral pleura and immunohistochemical staining showed caudal-type homeobox transcription factor 2 (CDX-2)(+), mucin-1(+), cytokeratin 7 (CK7)(+) and thyroid transcription factor-1 (TTF-1)(-) in the tumor cells (Fig. 1). TTF-1(-) in the tumor cells, confirming metastasis from colorectal adenocarcinoma (Fig. 1). The patient was then treated by chemotherapy with irinotecan, calcium folinate and fluorouracil every 14 days for four cycles; however, the patient succumbed to progression of the disease.
PET, CT and fused images. The tonsil was swollen and the largest standardized uptake value was 8.08 (scale bar, 10 cm). PET, positron emission tomography; CT, computed tomography.
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PET-CT revealed that the tonsil was swollen and the largest SUV was 8.08 (Fig. 2). Pathological examination was performed on the tonsil mass and the results indicated adenocarcinoma.