PMC9922796_01
Skin lesion of acquired reactive perforating collagenosis. (A) The patient exhibited central keratosis with brown crusts primarily on the trunk. (B) The Koebner phenomenon was observed on the back (indicated by the black arrow). (C) Multiple non-tender erythematous papules and eschars were observed on the lower limbs.
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The lesions gradually became exacerbated with severe pruritus, spreading all over the trunk of her body, right upper and left lower limb, part of which was covered with crust (Fig. 1).
(A) Pathology of the skin biopsy, observed using hematoxylin and eosin staining. (B) The epidermal spinous layer was thickened. The ulceration filled with lymphocytes and eosinophils. (C) Pathology of the skin biopsy, observed using Masson's staining. (D) Necrotic collagen fibers penetrated into the surface (indicated by the red circle).
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Masson's staining(as described below) revealed collagen fibers penetrating the surface (Fig. 2).