PMC9983077_01
PMC9983077_02
Four-year female with microcephaly.
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PMC9983077_02_10.1177_2333794X231157979-fig1.jpg
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The child had hypotonia in all limbs with bilateral planter extensor with increased deep tendon reflexes and cerebellar Romberg sign positive (Figure 1).
T1 iso intensity in bilateral periventricular deep white matter in the
hemisphere.
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PMC9983077_02_10.1177_2333794X231157979-fig2.jpg
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Similar changes in the cerebral hemisphere, brain stem, and cerebellum were present (Figures 2 and 3).
T2/FLAIR hyperintensity in bilateral periventricular deep white matter in the
hemisphere.
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PMC9983077_02_10.1177_2333794X231157979-fig3.jpg
fig3-2333794X231157979
Similar changes in the cerebral hemisphere, brain stem, and cerebellum were present (Figures 2 and 3).