PMC3891390_01
Multiple edematous, tender, erythematous nodules on the extensor surfaces of the legs.
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F1
In May, 2003 the patient presented with fatigue, myalgia, fever as well as multiple edematous, tender, erythematous to brownish subcutaneous nodular lesions on both upper and lower extremities and trunk (Figure 1).
Histological examination showed lympho-histiocytic infiltration in the septa and the periphery of the fat lobules consistent with lobular panniculitis (H&E stain, x400).
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F2
Biopsy of skin lesion revealed lobular panniculitis consistent with erythema nodosum (Figure 2).
Chest CT showed pericardial effusion with pulmonary edema and atelectasis.
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F3
Chest X-ray and chest CT scan showed cardiomegaly with pulmonary edema (Figure 3).