PMC3331876_01
a Right-eye posterior pole lesion at the time of presentation. b FFA photograph of the same lesion in venous phase showing hyperfluorescent mass with no pinpoint leakage. c ICG photograph revealed hypofluorescent lesion with hyperfluorescent margins. d B-scan ultrasonography showed a mid-reflective mass measuring 9.5 x 8.6 mm with a prominence of 3.9 mm.
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F1
The mass had some secondary changes and pigmentation in the inferior part and at the margins of the lesion (fig. 1a). Indocyanine green chorioangiography (ICG) revealed a hypofluorescent choroidal lesion with hyperfluorescent margins (fig. 1b, c). B-scan ultrasonography showed a bilobular choroidal mass with moderate reflectivity, compared to low reflectivity of choroidal melanoma, and measuring 9.5 x 8.6 mm with a prominence of 3.9 mm (fig. 1d).
a Biopsy specimen showing proliferation of epithelial cells with abundant extracellular matrix (hematoxylin-eosin, original magnification x40). b Same specimen showing PAS-positivity of the extracellular matrix (PAS stain, original magnification x40).
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F2
Histopathology of the obtained sample revealed compact interlacing cords of epithelial cells with fairly large amounts of amorphous extracellular matrix that stained positive with periodic acid-Schiff (PAS) stain (fig. 2a, b).