PMC5561625_01
Picture showing the patient with swelling at the superolateral angle of the left orbit
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Fig1
On clinical examination, there was a soft tissue swelling at the superolateral angle of the left orbit (Fig. 1).
Computed Tomography scan showing a well circumscribed and homogeneous left supraconal tumor
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Fig2
Gross picture of the excised mass
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Fig3
Low magnification showing a lesion with fascicular architecure in a predominantly fibrous background (haematoxylin & eosin stain, x 50)
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Fig4
Histopathology of the excised mass showed a tumor composed of haphazardly arranged spindle-shaped and oval cells in a predominantly fibrous background, interspersed with prominent dense bands of collagen that clamped residual glands (Figs. 4 and 5).
Higher magnification showing the residual glands that are encircled by the proliferation (haematoxylin & eosin stain, x 200)
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Fig5
Histopathology of the excised mass showed a tumor composed of haphazardly arranged spindle-shaped and oval cells in a predominantly fibrous background, interspersed with prominent dense bands of collagen that clamped residual glands (Figs. 4 and 5).
Higher magnification showing a stroma infiltrated by numerous inflammatory cells composed of lymphocytes, plasma cells and eosinophils (haematoxylin & eosin stain, x400)
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Fig6
The stroma was infiltrated by numerous inflammatory cells composed of lymphocytes, plasma cells and rare eosinophils (Fig. 6).
Immunohistochemical staining revealed the expression of smooth muscle actin (a) and ALK (b) by the neoplastic cells. Keratin highlights the residual glands (c). Ki-67 immunostaining showed a low proliferation index (d)
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Fig7