PMC8138198_01
a Chest CT on February 6, 2018 (before the administration of SOF/VEL), showed pleural effusion in the lower part of the right lung. The white arrows show pleural effusion. b Abdominal CT on February 6, 2018 (before the administration of SOF/VEL), showed ascites in the lower part of the liver. The white arrows show ascites.
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F1
February 6, 2018, showed ascites and pleural effusion (Fig. 1a, b) and she was diagnosed with decompensated liver cirrhosis.
a Chest CT on September 25, 2019 (after the administration of SOF/VEL), showed that the pleural effusion in the lower part of the right lung had disappeared completely. b Abdominal CT on September 25, 2019 (after the administration of SOF/VEL), showed that the ascites in the lower part of the liver had disappeared completely.
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F2
August 30, 2019. Abdominal CT performed on September 25 showed neither ascites nor pleural effusion (Fig. 2a, b).
Time course of serum ammonia level after SOF/VEL administration.
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F3
Hepatic encephalopathy (grade I-II), which appeared on July 23, 2019 (the patient claimed cloudiness of sensation, serum ammonia level of 112 mug/dL), disappeared on October 7, 2019 (serum ammonia level of 85 mug/dL) (Fig. 3).
Time course of serum albumin level after SOF/VEL administration.
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F4
In addition, she also showed marked improvements in the albumin level (Fig. 4) and in prothrombin time (Fig. 5).