PMC5771733_01
A and B, Cutaneous Langerhans cell histiocytosis. Macerated erythematous plaques on the inframammary folds.
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fig1
The eruption involved her axillae, inframammary (Fig 1, A and B) and inguinal folds, perineum, and gluteal cleft.
Atypical mononuclear cells with eccentric reniform nuclei infiltrating an eroded epidermis with eosinophils in the background. (Hematoxylin-eosin stain; original magnification: x200.)
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fig2
Langerhans cells infiltrating the upper reticular dermis, papillary dermis, and epithelium. (CD1a stain; original magnification: x20.)
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CD1a staining (Fig 3), consistent with LCH. Computed tomography of the abdomen and pelvis found lymphadenopathy in the left upper quadrant.