PMC8626741_01
MRI of the brain. Narrowing of the subarachnoid space. A pathological increase in the intensity of the signal by T2/TIRM and DWI from the cortex of the brain substance is determined, the change in the signal is symmetrical from the basal nuclei with their hemorrhagic transformation. Symmetrically increased T2/TIRM signal from the medial thalamus, periaqueductal gray matter
41983_2021_413_Fig1_HTML.jpg
PMC8626741_01_41983_2021_413_Fig1_HTML.jpg
Fig1
In the conclusion of MRI of the brain described the MRI picture of acute necrotizing encephalopathy (Fig. 1).
PMC8626741_02
Histological picture of brain lesions. a, b Inflammatory infiltration, spongy and perivascular edema, areas of necrosis, desquamation of the endothelium in the cerebral vessels. x200. c Fibrinoid necrosis of cerebral vessels. H&E staining. x100. d AHNE with the formation of a cyst. H&E staining. x200. e Severe necrobiotic neuronal damage. Nissl staining. x400
41983_2021_413_Fig2_HTML.jpg
PMC8626741_02_41983_2021_413_Fig2_HTML.jpg
Fig2
The pathological process mainly affected small vessels with varying degrees of segmental and total destruction of the endothelium, its swelling, desquamation, fibrinoid necrosis of the walls and pronounced perivascular edema (Fig. 2a-c).