PMC9283784_01
(A, B) orbital CT showed that the oncocytic carcinoma affects intracranial structures through the supraorbital fissure, accompanied by bone destruction (thick white arrow). (C) Oncocytic carcinoma destroyed the skull base bone and involved the dural structure (thick white arrow). (D, E, F) Orbital CT bone window showed the bone of the skull base and the outer orbital wall were absorbed or destroyed by the tumour.
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F1
The orbital computed tomography (CT) results visualised the tumour in the right posterior upper orbital space as fast growing and erosive in the cranio-orbital area, eroding and destroying the bone and protruding into the brain through the supraorbital fissure (Figure 1).
(A) the suspected tumour originated in the sphenoid sinus or invaded the sphenoid sinus from the cranio-orbital area (thick white arrow). (B) The tumour destroyed the right optic canal and involved the right optic nerve, and the side wall of the sphenoid sinus remained intact (thin white arrow). The left optic canal was intact (thin white arrow).
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F2
The bilateral optic canal bones were intact without tumour invasion, and the suspected eosinophilic carcinoma in the sphenoid sinus was removed (Figure 2).
(A) orbital MRI showed that the tumour broke through the skull base and involved the intracranial structure (thick white arrow). (B) Enhanced MRI showed enhanced performance of the dura mater located at the base of the skull (thick white arrow). (C, D) Postoperative enhanced MRI showed complete resection of the tumour. (E, F) We performed a frontal orbital craniotomy to remove the tumours in the cranio-orbital area, and simultaneously performed bone removal of the skull base and the lateral wall of the orbit. Postoperative CT showed that the bone involved in the tumour was completely removed (thick white arrow).
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F3
To avoid tumour recurrence, an extensive resection of the whole sphenoid wing and lateral orbital wall was performed (Figure 3).
(A) immunohistochemistry CK7 (-). (B) Immunohistochemistry P63 (-). (C) (HE 100x): Tumour cells were usually arranged in slices, beams or alveolar structures. Occasionally, there was extensive duct differentiation in tumours. The tumour had grown invasively, and perineural and vascular invasion were common. (D) (HE 200x), (E) (HE 400x): It could be seen that the tumour cells of eosinophilic carcinoma were large, round or polygonal, and the cytoplasm was finely granular. It was more pleomorphic than an eosinophilic adenoma. The nucleus was located in the centre of the cell and often had large and irregular nucleoli. HE: Hematoxylin-Eosin staining.
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F4
The nucleus is the centre of the cell, and nucleoli are often large and irregular (Figure 4).