PMC7711183_01
Macroscopic aspects of the tumor which appeared to be well circumscribed with nevertheless, in places, some irregular borders.
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PMC7711183_01_gr1.jpg
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It appeared to be well circumscribed with nevertheless, in places, some irregular borders (Fig. 1).
H&E staining at low power view. Grade 1 invasive carcinoma (in the circle) within the leaf-like typical aspect the phyllode tumor (arrow).
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PMC7711183_01_gr2.jpg
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Within this phyllode tumor, a 3 mm focus of NST grade 1 invasive carcinoma was also found (Fig. 2, Fig. 3).
Immunohistochemistry with calponin antibody. The absence of myoepithelial cells confirms the invasive status of the tumor.
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PMC7711183_01_gr4.jpg
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It was characterized by invasive glandular structures invading the stroma without visible myoepithelial cell (p63 and calponin immunostaining were negative) (Fig. 4).