PMC3859158_01
Coronal (a) and transverse (b) contrast-enhanced computed tomography (CT) scan showed a 9.2 x 9.5 x 11.5 cm, huge, and well-defined left suprarenal mass (arrow) arising either from adrenal gland, pancreas, or retroperitoneum. The mass demonstrated mild heterogeneous enhancement with central cystic/necrotic area. No evidence of lymphadenopathy or regional/distant metastasis was identified.
CRIM.ONCMED2013-416713.001.jpg
PMC3859158_01_CRIM.ONCMED2013-416713.001.jpg
fig1
No evidence of lymphadenopathy or regional/distant metastasis was identified (Figures 1(a) and 1(b)).
Microscopic examination of the pancreatic tail tumor. (a) Tumor was composed of monomorphic spindle-shaped Schwann cells with poorly defined eosinophilic cytoplasm and pointed basophilic nuclei set in a collagenous stroma. Focal nuclear palisading is noted (H&E stain, magnification power: 10x). (b) Areas characteristic for Antoni B composed of Schwann cells with inconspicuous cytoplasm and nuclei suspended in myxoid matrix are identified. Scattered degenerated nuclei in a hyalinized stroma suggestive of ancient schwannoma were present. No mitosis or necrosis was noted (H&E stain, magnification power: 40x).
CRIM.ONCMED2013-416713.002.jpg
PMC3859158_01_CRIM.ONCMED2013-416713.002.jpg
fig2
Focal nuclear palisading was noted (Figure 2(a)). No mitosis or necrosis was noted (Figure 2(b)).
Immunohistochemical examination of the pancreatic tail tumor showed diffuse and strong positivity to S100 protein (magnification power: 40x).
CRIM.ONCMED2013-416713.003.jpg
PMC3859158_01_CRIM.ONCMED2013-416713.003.jpg
fig3
Immunohistochemically, tumor cells stained diffusely and strongly positive for S100 protein (Figure 3).