PMC7490995_01
Scheme of isolated thoracic perfusion. Aorta and vena cava are balloon blocked at the level of the diaphragm. Both upper arms are blocked with pneumatic cuffs. Chemotherapy is administered over 15 min via implanted or angiographic carotid artery catheters. After 15 min all blocks are released and chemofiltration for elimination of residual drugs is started.
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In the first isolated thoracic perfusion (Fig. 1) on 7th December 2010 the chemotherapeutic agents were administered via two angiographically placed common carotid artery catheters (Fig. 2) at a dosage of totally 100 mg cisplatin, 60 mg adriamycin and 20 mg mitomycin followed by chemofiltration in order to reduce systemic toxicity.
a, b, c a) CT-scan before, b) CT-scan four weeks after, c) CT-scan seven months after isolated thoracic perfusion.
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The tumor was no longer detectable in the July 2011 CT-scan (Fig. 3a, b, c).
a, b a) End-to-side implantation of the intra-arterial Jet-Port Allround catheter, b) Contrast imaging of carotid artery through implanted Jet-Port catheter.
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During the second in-patient stay from 2nd January 2011, a common carotid artery port catheter was implanted on both sides (Fig. 4).