PMC9676140_01
Intensity modulated radiation therapy dose distributions for parotid and submandibular glands treated with 20 Gy in 4 fractions delivered in 2 fractions in consecutive days separated by 1 week, showing A) coronal view of both parotid and submandibular glands, B) axial view of bilateral parotid glands, and C) axial view of bilateral submandibular glands.
gr1.jpg
PMC9676140_01_gr1.jpg
fig0001
Figure 1 shows the dose-distribution maps for the parotid and submandibular glands.
Persistent reduction in measured salivary output (5 cotton-ball weight; bottom), subjective sialorrhea (middle), and subjective oral secretion quality of life (top; y-axis inverted to represent bottom values as best) after intensity modulated radiation therapy to major salivary glands. Red-shaded bar indicates when radiation-therapy treatments were delivered.
gr2.jpg
PMC9676140_01_gr2.jpg
fig0002
Figure 2 depicts how both objective and subjective sialorrhea measures improved over time.
Dose-volume histograms for several structures, showing sparing of dose to sensitive organs at risk with intensity modulated radiation therapy. Clinical and planning tumor volumes include bilateral parotid and bilateral submandibular glands.
gr3.jpg
PMC9676140_01_gr3.jpg
fig0003
Figure 3 plots the dose-volume histogram for several organs illustrating the relative sparing of the dose with IMRT.