PMC4768893_01
Tumor of entire left breast (rupture size 22x18 cm).
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Physical examination revealed a huge mass that was ulcerated, having an irregular surface, occupying the entire left breast (Figure 1).
CT chest shows huge inhomogeneous enhanced mass at left breast.. Abbreviation: CT, computed tomography.
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CT scan of the chest was performed which showed a large inhomogeneous enhancing mass at the left breast, measuring 13.4x14.8x14.3 cm in size with a round-shaped nodule in the posterior basal segment of the left lower lung, measuring 0.6 cm in size (Figure 2).
Microscopic study of phyllodes tumor.. Notes: Microscopic study of phyllodes tumor displays increased stromal cells with cleft- and leaf-like appearance of ducts and malignant spindle cells in the stroma with frequent mitoses (arrows) (H&E x40).. Abbreviation: H&E, hematoxylin and eosin.
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The histopathology of the surgical specimen (Figure 3) revealed a malignant phyllodes tumor; 13 mitoses/10 high power field, surgical margins were approached by the tumor at the lateral and deep margins.