PMC9234253_01
Chest computed tomography scan revealed ground-glass opacity in the basal area of both lungs and nodule in the left lower lobe.
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Chest radiography revealed ground-glass opacity in the bilateral lower lung fields, and a chest computed tomography scan revealed ground-glass opacity in the basal area of both lungs and a nodule in the left lower lobe (Fig. 1).
Histological findings of the lung specimen collected via transbronchial cryobiopsy (2A). Results showed the deposition of Congo red-stained AL (2B) with birefringence using polarized light (2C). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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TBLC sites were left B8b, B9a, and B9b. The pathological findings of the TBLC-collected specimen from left B9a showed the deposition of Congo red-stained AL with birefringence under polarized light (Fig. 2A-C).
PMC9234253_02
Chest computed tomography scan revealed right pleural effusion and multiple micronodules with a random distribution in both lung fields.
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Chest computed tomography scan revealed right pleural effusion and multiple micronodules with a random distribution in both lung fields (Fig. 3).
Histological analysis of the lung specimen collected via TBLC showed the deposition of fibrin and infiltration of lymphocytes, eosinophils, and macrophages in the alveolar space (4A). Moreover, it revealed mild thickening of the alveolar wall (4B) and pulmonary arterioles (4C), both of which had amyloid deposition with positive Congo-red staining findings (4C, 4D) accompanied by birefringence using polarized light (4E). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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However, those taken via TBLC revealed mild thickening of the alveolar wall and pulmonary arterioles, both of which had amyloid deposition with a positive finding on Congo-red staining (Fig. 4A-D) accompanied by birefringence using polarized light (Fig. 4E).