PMC8326604_01
(a) Bone marrow biopsy which showed a hypercellular bone marrow and florid population of B-cell lymphocytes on hematoxylin and eosin stain at 40x magnification. (b) Bone marrow biopsy which showed a hypercellular bone marrow and florid population of B-cell lymphocytes on hematoxylin and eosin stain at 40x magnification. (c) Bone marrow biopsy which showed a hypercellular bone marrow and florid population of B-cell lymphocytes that stained positive for CD5. (d) Bone marrow biopsy which showed a hypercellular bone marrow and florid population of B-cell lymphocytes that stained positive for CD20. (e) Bone marrow biopsy which showed a hypercellular bone marrow and florid population of B-cell lymphocytes that stained positive for CD23.
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The patient then underwent a bone marrow biopsy, which showed a hypercellular bone marrow and florid population of B-cell lymphocytes positive for CD5, CD20, CD22, CD43, CD79a, cyclin D1, and BCL-2 with rare CD10 positive B-cell lymphocytes, and negative CD23 (Figure 1a-e).