PMC9679634_01
T2-weighted magnetic resonance imaging showed a large uneven tumor mass at the prostate with an unclear border with the seminal vesicles and anterior rectum, tumor appeared hyper-intensive. The arrows suggested the tumor. (A) sagittal view; (B) transection view; (C) diffusion-weighted imaging (DWI); (D) apparent diffusion coefficient (ADC) maps.
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T2 signal changes, unclear edges, unclear demarcation with the anterior wall of the seminal vesicle glands and rectum ( Figures 1A, B ), and this was accompanied by DWI high signal, ADC low value ( Figures 1C, D ), considering malignant neoplastic lesion, the possibility of prostate source, the anterior wall of the rectum and the possibility of involvement of the seminal vesicle glands. There were no significant abnormalities on systemic bone scans. The patient had a guided transctumal trans-perineal prostate puncture on June 8, and pathological reports suggested a GIST.
Histological microscopic examination of pathological biopsy showed that no obvious necrosis was found in the tumor, and the tumor cells were mainly spindle cells. (Original magnification: (A), x50; (B), x100).
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Prostate tissue and significant neoplastic necrosis were not seen in each section, and tumor cells were mainly spindle-shaped ( Figures 2A, B ).
Immunohistochemistry showed positive expression of CD-117(A), CD-34(B) and DOG-1(C)(Original magnification: (A1), (B1), (C1), x100;(A2), (B2), (C2), x200;(A3), (B3), (C3), x400).
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DOG-1 (+) ( Figure 3C1-C3  ), SMA (weak +), S 100 (-), DES ( ),PCK(-), Ki-67 (5%). Due to the patient's private motives, the patient refused radical prostatectomy and received only imatinib treatment.