PMC9975676_01
CT Chest at the time of presentation depicting a 2.0 by 1.5 cm right lower lobe nodule in axial (A) and coronal views (B).
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Subsequently, CT imaging of his chest showed a 2.0 x 1.5 cm elongated, partially calcified nodule along the posterior aspect of the right major fissure without any significant mediastinal and hilar lymphadenopathy (Fig. 1).
CT Chest at nine-month interval depicting a 3.0 by 1.7 cm right lower lobe mass in axial (panel A) and coronal views (panel B).
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Serial imaging survey showed a stable nodule at the 3-month interval, however, at 9-month follow up, the nodule showed growth in size to 3.0 x 1.7 x 1.5 cm with the anterior border abutting the fissure (Fig. 2).
Pathological sections of biopsied tissue with a section of the lung showing eosinophilic amorphous material (A). Congo red stain is positive for waxy amyloid deposit (B). There is apple-green birefringence upon polarization consistent with amyloid deposition (C). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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The patient underwent CT guided biopsy of the mass showing the presence of amyloid protein (Fig. 3).