PMC9355841_01
Panoramic radiograph showing a radiolucent lesion in the left posterior mandible, between second premolar and first molar
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F1
On radiographic examination, the lesion was a well-defined radiolucency located between the premolar and molar area (i.e., teeth #19-20) (Fig.1). 
Cone-beam computed tomography scan demonstrating a unilocular radiolucency with buccal expansion and perforation: (A) axial and (B) sagittal views
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F2
However, expansion and perforation of the buccal cortical plate were noted on cone-beam computed tomography scan (Fig. 2A and 2B). 
Nests of odontogenic epithelium (arrows) and multinucleated giant cells (arrowheads) with a low magnification (x20) showing the two lesions relative to each other
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F3
Also, nests and strands of bland odontogenic epithelium were evident (Fig. 3). 
Immunoreactivity of odontogenic epithelium for pan-cytokeratin (A, x40) and giant cells for CD68 (B, x40)
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F4
The results of immunohistochemical staining with pan-cytokeratin and CD68 confirmed the odontogenic epithelium and multinucleated giant cells (Fig. 4A and 4B).