PMC3895281_01
CT scan. Mass contiguous with the uterine fundus.
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CT scan revealed a markedly enlarged uterus with an ill defined right adnexal/lower quadrant mass contiguous with the uterine fundus suggestive of possible sarcoma (Fig. 1). CA-125 was noted to be 407.
H&E photo. High-power view of diffusely infiltrative epithelioid tumor cells with few mitotic figures (400 x).
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Histologic sections of the debulked uterine mass and myometrium involved by tumor demonstrated a poorly circumscribed tumor with infiltrative borders containing poorly differentiated epithelioid and spindle cells with a high nuclear/cytoplasm ratio and scant cytoplasm (Fig. 2).
CD99 immunostain. Strong reactivity of neoplastic cells for this marker (400 x).
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Fli-1, and Vimentin were positive on immunohistochemical stains (Fig. 3). Final pathology revealed high-grade primitive neuroectodermal tumor.