PMC7378716_01
Dermal nodule with well-circumscribed but unencapsulated margin.
10.1177_2050313X20938246-fig1.jpg
PMC7378716_01_10.1177_2050313X20938246-fig1.jpg
fig1-2050313X20938246
Histological examination reveals a well-circumscribed lesion consisting of spindle and epithelioid cells that show prominent granular eosinophilic cytoplasm and vesicular nuclei (Figures 1-3).
Epithelioid cells with prominent granular eosinophilic cytoplasm (10x).
10.1177_2050313X20938246-fig2.jpg
PMC7378716_01_10.1177_2050313X20938246-fig2.jpg
fig2-2050313X20938246
Histological examination reveals a well-circumscribed lesion consisting of spindle and epithelioid cells that show prominent granular eosinophilic cytoplasm and vesicular nuclei (Figures 1-3).
Spindle and epithelioid cells with prominent granular eosinophilic cytoplasm
(40x).
10.1177_2050313X20938246-fig3.jpg
PMC7378716_01_10.1177_2050313X20938246-fig3.jpg
fig3-2050313X20938246
Histological examination reveals a well-circumscribed lesion consisting of spindle and epithelioid cells that show prominent granular eosinophilic cytoplasm and vesicular nuclei (Figures 1-3).
CD68 is positive in granular cells.
10.1177_2050313X20938246-fig4.jpg
PMC7378716_01_10.1177_2050313X20938246-fig4.jpg
fig4-2050313X20938246
Immunohistochemical staining shows tumor cells staining positive for CD68 and negative for S100 and AE1/AE3/PCK26 (Figures 4 and 5).
S100 is negative in granular cells.
10.1177_2050313X20938246-fig5.jpg
PMC7378716_01_10.1177_2050313X20938246-fig5.jpg
fig5-2050313X20938246
Immunohistochemical staining shows tumor cells staining positive for CD68 and negative for S100 and AE1/AE3/PCK26 (Figures 4 and 5).
SOX10 is negative in granular cells.
10.1177_2050313X20938246-fig6.jpg
PMC7378716_01_10.1177_2050313X20938246-fig6.jpg
fig6-2050313X20938246
The SOX10 and NSE are negative (Figures 6 and 7).
NSE is negative in granular cells.
10.1177_2050313X20938246-fig7.jpg
PMC7378716_01_10.1177_2050313X20938246-fig7.jpg
fig7-2050313X20938246
The SOX10 and NSE are negative (Figures 6 and 7).