PMC9285114_01
Fundus images at the time of diagnosis. (a) Fundus appearance of the AZOOR lesion as an annular ring of yellowish reflex with an about 4-5 disc diameter in the right eye, (b) fundus photo showing the normal left eye
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F1
Fundus examination demonstrated an annular ring of yellowish reflex with an about 4-5 disc diameter at the posterior pole in the right eye (Figure 1 (Fig. 1)).
FAF images at the time of diagnosis. (a) Slightly increased autofluorescence, more prominent at the border on FAF imaging in the right eye, (b) normal autofluorescence image of the left eye
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F2
There was slightly increased hyperautofluorescence, more prominent at the temporal border on fundus autofluorescence (FAF) imaging (Figure 2 (Fig. 2)).
Infrared (IR) images at the time of diagnosis. (a) IR image of the right eye showed the lesion contour consistent with the FAF and color images, (b) IR image of the left eye
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F3
Infrared fundus image showed the lesion contour consistent with the FAF and color images (Figure 3 (Fig. 3)).
SD-OCT images at the time of diagnosis. (a) Spectral domain optical coherence tomography (SD-OCT) revealed hyperreflective dots between RPE and the ellipsoid zone (EZ) and loss or irregularity of the EZ, (b) SD-OCT image of the left eye
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F4
EZ (Figure 4 (Fig. 4)). En-face OCTA outer retinal slab demonstrated multiple hyperreflective dots in a starry-sky appearance (Figure 5 (Fig. 5)).
OCTA images at the time of diagnosis . (a) Multiple hyperreflective dots in a starry-sky appearance on the en-face OCTA outer retinal slab of the right eye, (b) OCTA image of the left eye
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F5
EZ (Figure 4 (Fig. 4)). En-face OCTA outer retinal slab demonstrated multiple hyperreflective dots in a starry-sky appearance (Figure 5 (Fig. 5)).
Fundus images at 2-week examination after the treatment. (a) The retinal lesion with the annular ring of yellowish reflex disappeared on the color fundus image of the right eye, (b) view of left fundus
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F6
The retinal lesion with annular ring of yellowish reflex disappeared (Figure 6 (Fig. 6), Figure 7 (Fig. 7)).
FAF images at 2-week examination after the treatment. (a) FAF image of the right eye, (b) FAF image of the left eye
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F7
The retinal lesion with annular ring of yellowish reflex disappeared (Figure 6 (Fig. 6), Figure 7 (Fig. 7)).
SD-OCT images at 2-week examination after the treatment. (a) Marked recovery in EZ and outer segment of photoreceptors on SD-OCT images in the right eye, (b) SD-OCT image of the left eye
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F8
EZ and the outer segment of the photoreceptors on SD-OCT images (Figure 8 (Fig. 8)). En-face structural OCTA images showed an obvious decrease in the hyperreflective dots (Figure 9 (Fig. 9)).
OCTA images at 2-week examination after the treatment. (a) An obvious decrease in the hyperreflective dots on en-face OCTA, (b) en-face OCTA image of the left eye
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F9
EZ and the outer segment of the photoreceptors on SD-OCT images (Figure 8 (Fig. 8)). En-face structural OCTA images showed an obvious decrease in the hyperreflective dots (Figure 9 (Fig. 9)).