PMC8082416_01
PMC8082416_02
Enhanced magnetic resonance imaging (MRI) of the right thigh revealed bone thinning of the right femur, surrounding a soft tissue mass shadow around the femur and high possibility of malignant tumor.
fendo-12-622674-g001.jpg
PMC8082416_05_fendo-12-622674-g001.jpg
f1
IFITM5 mutation (c, -14C >T) ( Supplementary Figure 1 ).
PMC8082416_03
PMC8082416_04
PMC8082416_05
Enhanced magnetic resonance imaging (MRI) of the right thigh revealed bone thinning of the right femur, surrounding a soft tissue mass shadow around the femur and high possibility of malignant tumor.
fendo-12-622674-g001.jpg
PMC8082416_05_fendo-12-622674-g001.jpg
f1
IFITM5 mutation (c, -14C >T) ( Supplementary Figure 1 ).
The HE staining of pathological specimens. (A) Neoplastic spindle cells and edema interstitial; (B) cartilage-like matrix and bone-like matrix with osteoblast cells lined around. (C) Atrophic striated muscle tissue.
fendo-12-622674-g002.jpg
PMC8082416_05_fendo-12-622674-g002.jpg
f2
HE staining was also performed on previous pathological specimens ( Figure 2 ).
PMC8082416_06
PMC8082416_07
X-ray of the right femur indicated inhomogeneous bone density losses of the right femur, cortical thinning, transverse sclerotic lines at the right distal femur and interface of the epiphysis and metaphysis of the proximal tibia, and excessive callus formation at the cortical margins.
fendo-12-622674-g003.jpg
PMC8082416_07_fendo-12-622674-g003.jpg
f3
The callus was smaller than in 2016 ( Figure 3 ).
PMC8082416_08