PMC4873600_01
Mammography.. Mediolateral oblique view revealing skin thickening and distortion around the left nipple (arrow). No tumor or calcification is apparent.
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May 2009, she complained of skin-thickening and crust formation at the left areola. Mammography revealed skin-thickening and distortion around the left nipple (Fig. 1).
Magnetic resonance imaging.. A mass with irregular margins. The mass shows heterogeneous hyperintensity on T2-weighted imaging (A), and hypointensity on T1-weighted imaging (B). Contrast-enhanced T1-weighted imaging shows enhancement of the mass (C).
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It was heterogeneous and hyperintense on T2-weighted imaging, hypointense on T1-weighted imaging, and gradually enhanced in a dynamic study (Fig. 2).
Pathology (gross).. (A) The resected specimen, showing an irregular mass accompanied by crust formation and skin thickening at the areola (arrows). (B) Cross-section of the specimen (vertical arrow in A). A brownish irregular mass leading into the skin thickening is seen beneath the nipple.
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Pathology (microscopy).. Microscopic examination of the surgically resected specimen, revealing oval-shaped cells arranged in the form of endovascular cells, accompanied by mitosis and background fibrosis.
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Histopathological examination revealed oval-shaped neoplastic stromal cells arranged in sinusoidal pattern, accompanying mitoses and background fibrosis (Fig. 4).