PMC4531175_01
Case 1 demonstrates facial eczema herpeticum.
CRIHEP2015-463825.001.jpg
PMC4531175_01_CRIHEP2015-463825.001.jpg
fig1
On physical examination, her temperature was 100.2 F and she had an erythematous rash with papules and scaling over the malar region of her face, consistent with eczema herpeticum, Figure 1.
PMC4531175_02
Case 2 demonstrating intraepidermal vesiculation with associated acantholysis and multinucleated cells characteristic of herpes simplex virus.
CRIHEP2015-463825.002.jpg
PMC4531175_02_CRIHEP2015-463825.002.jpg
fig2
Skin biopsies demonstrated multinucleated cells characteristic of HSV, Figure 2.
PMC4531175_03
Case 3 demonstrates multiple white raised irregularly shaped lesions on the surface of the liver that were noted at the time of a diagnostic laparoscopy, with biopsies consistent with HSV-2 hepatitis and confirmed with immunofluorescent staining of the tissue culture cells.
CRIHEP2015-463825.003.jpg
PMC4531175_03_CRIHEP2015-463825.003.jpg
fig3
Biopsies, confirmed with immunofluorescent staining of the tissue culture cells, were consistent with HSV-2 hepatitis, Figure 3.