PMC5247631_01
Gross appearance of colon after emergent colectomy showing circumferential ulceration of distal 90 cm.
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F1
His colon specimen showed hemorrhagic mucosa and diffuse ulceration (Figure 1).
Colon biopsy histology showing a cluster of non-caseating granulomata (hematoxylin and eosin x40).
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F2
Histologic evaluation showed non-caseating granulomas (Figure 2).
PMC5247631_02
Severe ulcerations with spontaneous bleeding of distal 30 cm of colon.
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F3
Sigmoidoscopy showed severe, continuous inflammation of the rectosigmoid (Figure 3).
Rectosigmoid biopsy histology showing melanosis coli representing lipofuscin deposition (hematoxylin and eosin x10).
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F4
Pathology demonstrated cryptitis with crypt abscesses, dense inflammation with loss of normal architecture, ulcerations, and melanosis coli (Figure 4).