PMC5724945_01
(A) CT scan depicts an expansile lytic lesion in T6 vertebra that destroys the cortex of the vertebral body (arrows), Sagittal; (B) and axial; (C) fat-saturated (FS) T1-weighted MRI with intravenous gadolinium contrast demonstrates compression fracture of vertebral body and the extent of disease in the marrow cavity, soft tissues and epidural space; (D) computed tomography guided needle biopsy
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CT scan revealed a lytic lesion involving the T4 vertebral body (Figure 1 A). On MRI, a compression fracture of the vertebral body with small epidural component was depicted (Figure 1 B,C). The supposed spinal metastatic functional paraganglioma was confirmed by computed tomography guided needle biopsy (Figure 1 D).
(A) tumor cells arranged in solid nests with increased number of mitoses; (B) tumor cells positive for chromogranin A
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The histologic and immunohistochemical assays revealed a paraganglioma (Figure 2 A,B).
MRI of the lumbar spine, sagittal section, T1: (A) T2; (B) and gadolinium-enhanced T1-weighted; (C) sequences: presence of nodular bone metastases with a halo (arrows)
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However, MRI revealed small new lesions in lumbar spine 6 months later (Figure 3 A,B,C).