PMC8189795_01
Photograph of the anterior segment of the right eye after pharmacological mydriases, showing posterior synechia between 12 and 2 h. Deposition of the iris pigment in the anterior capsule due to posterior synechia (patient 1).
CRIOPM2021-1812271.001.jpg
PMC8189795_01_CRIOPM2021-1812271.001.jpg
fig1
However, at 8 months after the initial presentation, while on the final phase of steroid tapering (prednisolone 2.5 mg every other day), she presented with ciliar hyperaemia and pain in the right eye (Table 1) and unilateral anterior nongranulomatous uveitis was detected (Figure 1).
PMC8189795_02
Pathological specimen obtained by renal biopsy (x100). Hematoxylin-eosin. Diffuse infiltration of inflammatory cells, mainly consisting of lymphocytic infiltrate, interstitial fibrosis, and tubular atrophy. The glomeruli are normal (patient 2).
CRIOPM2021-1812271.002.jpg
PMC8189795_02_CRIOPM2021-1812271.002.jpg
fig2
Additional investigations, namely, for autoimmune diseases and multiple myeloma, were negative, and a kidney biopsy was performed which was consistent with acute TIN (Figure 2).
PMC8189795_03
PMC8189795_04