PMC3175359_01
Clinical features of lower extremities. Palpable purpura progressed, turning into blisters and forming retiform ulcers.
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F1
The purpuric lesions soon progressed to skin ulcers (fig. 1).
Microscopic examination of palpable purpura. Severe pandermal leucocytoclastic vasculitis without granulation (HE, original magnification x40; inset: x400).
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F2
Histopathological examination of the purpura and peripheral lesion on the left lower limb revealed severe pandermal leucocytoclastic vasculitis with fibrinoid degeneration but no granuloma (fig. 2).
Microscopic examination of the kidney biopsy specimen. Mild mesangial cellular proliferation and expansion. Mesangial and diffuse IgA deposits were observed and crescents were absent (HE, original magnification x100; inset: direct immunofluorescence x100).
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F3
A renal biopsy that was additionally conducted to evaluate renal involvement revealed mild mesangial cellular proliferation and expansion as well as mesangial and diffuse IgA deposits (fig. 3).