PMC4026149_01
Radiological and histopathological results of the first twin-brother. (A) Chest X-ray showing enlarged hili and disseminated micronodular changes with predominance to middle zones; (B) Selected chest CT scan showing parenchymal micronodular changes; (C). Transbronchial peripheral lung biopsy showing non-caseating granulomas consisting of multinucleated giant cells, epithelioid cells, and surrounding lymphocytes.
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His chest X-ray was performed as part of a routine medical check-up before admission (Figure 1A). After his X-ray had been evaluated, he was admitted to the pulmonary unit of a district hospital, where lung CT scans were performed (Figure 1B). Allergy, Medical University of Lodz for further diagnosis. Although BAL fluid cellular pattern and laboratory results were not typical for sarcoidosis (Table 1), transbronchial lung biopsy (TBLB) revealed non-caseating granulomas (Figure 1C), confirming the initial diagnosis.
CT-scan of the case's twin brother showing enlarged hilar lymph nodes and disseminated micronodules.
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Chest CT scans confirmed the presence of bilateral hilar enlargement and disseminated nodular changes and thickening of bronchovascular bundles with predominance of upper and middle zones (Figures 2, and 3A).
Radiological and histopathological results of thecase's mother; (A) CT-scan showing enlarged hilar lymph nodes and disseminated micronodular changes; (B) Transbronchial peripheral lung biopsy showing noncaseating granulomas.
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Chest CT scans confirmed the presence of bilateral hilar enlargement and disseminated nodular changes and thickening of bronchovascular bundles with predominance of upper and middle zones (Figures 2, and 3A). The mother's TBLB showed non-ca-seating granulomas (Figure 3B).