PMC3036637_01
Right hilar mass noted with multiple pulmonary nodules scattered throughout the lung parenchyma.
1752-1947-5-19-1.jpg
PMC3036637_01_1752-1947-5-19-1.jpg
F1
A 2.5 cm mass was noted in the periphery of the left upper lobe (Figure 1).
Multiple hypodensities noted in the liver, and an isolated lesion noted in the head of the spleen.
1752-1947-5-19-2.jpg
PMC3036637_01_1752-1947-5-19-2.jpg
F2
Several hypodensities were noted in the kidneys, liver, and spleen (Figure 2).
A massive conglomerate of periaortic, aortocaval lymph nodes and retroperitoneal necrotic mass measuring up to 14.4 cm, which encases the abdominal vasculature.
1752-1947-5-19-3.jpg
PMC3036637_01_1752-1947-5-19-3.jpg
F3
An ill-defined necrotic retroperitoneal mass measuring 14.4 cm, encasing the abdominal vasculature, was seen in the periaortic and aortocaval areas (Figure 3).
Biopsy of supraclavicular lymph node showing undifferentiated giant cells.
1752-1947-5-19-4.jpg
PMC3036637_01_1752-1947-5-19-4.jpg
F4
The histopathology revealed metastatic poorly differentiated squamous cell carcinoma with focal positivity for beta-hCG (Figures 4 and 5).
Immunohistochemistry showing focal positivity for beta-hCG.
1752-1947-5-19-5.jpg
PMC3036637_01_1752-1947-5-19-5.jpg
F5
The histopathology revealed metastatic poorly differentiated squamous cell carcinoma with focal positivity for beta-hCG (Figures 4 and 5).
Immunohistochemistry showing cells that stain positive for P63, highly suggestive of squamous cell carcinoma.
1752-1947-5-19-6.jpg
PMC3036637_01_1752-1947-5-19-6.jpg
F6
CK, 7; AE1/AE3, beta-hCG, CAM 5.2, and P63 positivity (Figure 6). CK 20, CEA, CA 19-9 AFP, and
Immunohistochemistry showing positivity for CK 7 on the cell membrane, suggestive of a carcinoma, most likely lung.
1752-1947-5-19-7.jpg
PMC3036637_01_1752-1947-5-19-7.jpg
F7
TTF were negative (Figure 7). These markers were consistent with a poorly differentiated or undifferentiated non-small cell carcinoma (squamous type) with beta-hCG positivity.