PMC3825666_01
Abdominal computed tomography showed a solid heterogeneous tumor of 12 cm in diameter in the tail of the pancreas with central necrosis (blue arrow indicates the tumor).
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The abdominal computed tomography (CT) showed a solid heterogeneous 12 x 10 cms mass located in the tail of the pancreas displacing the stomach and compressing the left kidney (Fig. 1).
Cut section of the 12 x 9 x 6 cm grayish-brown color tumor. It was solid and firm with focal areas of hemorrhage arising from the smooth muscle of the splenic vein.
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The mass was a solid and firm gray-brown color tumor, with focal areas of hemorrhage on the cut section (Fig. 2).
Hematoxylin and eosin stain (4x magnifications) revealed predominantly fusiform cells, with a high rate of atypical mitotic figures. (A) Intraluminal tumor growth of a leiomyosarcoma originating from the splenic vein (hematoxylin and eosin stain, x40 magnification). (B) Hematoxylin and eosin stain (x200 magnification) revealed predominantly fusiform cells, with a high rate of atypical mitotic figures.
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Tumor cells were positive for smooth cell immunohistochemical markers (smooth muscle actin and desmin) and were negative for epithelial markers (keratin), neuronal markers (S100), and hematopoietic markers (CD34) (Figs. 3 and 4).
The tumor cells stained strongly positive for smooth muscle actin (100x).
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Tumor cells were positive for smooth cell immunohistochemical markers (smooth muscle actin and desmin) and were negative for epithelial markers (keratin), neuronal markers (S100), and hematopoietic markers (CD34) (Figs. 3 and 4).