PMC9526233_01
(A) Computed tomography revealing presence of endobronchial mass in the left main bronchus causing atelectasis in her left upper lung. (B) Bronchoscopical finding revealing the endobronchial mass.
gr1.jpg
PMC9526233_01_gr1.jpg
fig1
A computed tomography (CT) scan of her chest revealed a presence of endobronchial mass in the left main bronchus which caused atelectasis of her upper lobe of left lung (Fig. 1A). Bronchoscopy revealed an endobronchial tumor which obstructed the left upper lobe bronchus (Fig. 1B).
Gross specimen of the endobronchial mass after removal showing a smooth polypoid tumor and cut surface.
gr2.jpg
PMC9526233_01_gr2.jpg
fig2
She underwent a transbronchial biopsy of the endobronchial tumor (Fig. 2).
Pathological findings of the endobronchial mass showing spindle-shaped cells with nuclear atypicality, suggesting leiomyosarcoma.
gr3.jpg
PMC9526233_01_gr3.jpg
fig3
Histopathological examination showed spindle-shaped cells with nuclear atypicality, numerous mitoses and area of tumor cell necrosis, characterized by positive staining for smooth muscle actin (SMA), desmin and caldesmon, as well as negative staining for CD34, CD31 and S-100; suggesting histological diagnosis of leiomyosarcoma (Fig. 3).
A positron emission tomography (PET)-CT with 18F-fluorodeoxyglucose (FDG) shows the accumulation of the tracer in a tumor in the endobronchial mass (A) and the uterus (B).
gr4.jpg
PMC9526233_01_gr4.jpg
fig4
A positron emission tomography (PET)-CT revealed uterus tumor with moderate uptake of 18F-fluorodeoxyglucose (FDG) (Fig. 4), suggesting uterine malignancies.
Histological findings of resected specimens of uterus, which present the similar findings to the biopsied specimen of the endobronchial mass.
gr5.jpg
PMC9526233_01_gr5.jpg
fig5
Histological findings of the resected uterus were similar to the preoperative biopsied bronchial specimen (Fig. 5).