PMC10026027_01
Computed tomography (CT) showed two masses in the right lower lobe (a, b). Contrast-enhancing CT showed the masses were mostly enhanced well with relatively low enhancement at the central region (c) and multiple lymphadenopathies (d-f).
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Chest computed tomography (CT) revealed two masses, 29 and 52 mm in diameter, in the right lower lobe of the lung, accompanied by pleural effusion and bone metastasis at the right sixth rib (Fig. 1a and b). The masses were mostly well enhanced with relatively low enhancement, suggesting a necrotic change in the central region (Fig. 1c). Several lymph nodes in the subtracheal and right hilar regions were enlarged and fused (Fig. 1d-f).
Positron emission tomography-computed tomography showed positive uptake in the masses in lung (b), swelled lymph nodes (a), right rib (b), and bilateral ilium (c, d).
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Positron emission tomography-CT demonstrated positive uptake in the bilateral ilium, as well as in the masses in the lung, swollen lymph nodes, and right rib (Fig. 2).
Histopathological image of the biopsy specimen of a subtracheal lymph node demonstrated small nests composed of uniform round cells without necrosis. Ki-67 index was 32.5%. 3a, hematoxylin and eosin-stained section (magnification 400x); 3b, immunohistochemistry staining with Ki-67 (magnification 400x).. *Color should be used for Fig. 2, Fig. 3. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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Histologically, the tumour formed small nests composed of uniform round cells without necrosis and exhibited a few mitoses (three mitoses per 2 mm2) (Fig. 3).