PMC9762491_01
Brain CT and MRI of patient 1 before medication (A-D). (A, B): The density of the inferior pole of both the temporal lobes was slightly decreased. (C): DWI showed that white matter signals under the gray matter of the inferior temporal pole were limited on both sides. (D): ADC showed symmetrical low signal changes.Brain MRI findings of patient 1 at the diagnosis of HHV-6B encephalitis (E, F). (E): DWI showed that bilateral inferior temporal poles were diffusively limited and symmetrical, with upwards involvement of the bilateral basal ganglia and subgray matter region of the medial lateral temporal lobe. (F): ADC presented high signal changes.
fimmu-13-1003254-g001.jpg
PMC9762491_01_fimmu-13-1003254-g001.jpg
f1
Magnetic resonance imaging (MRI) and computed tomography (CT) of the brain revealed slight ischemic changes, without other obvious abnormalities (Figures 1A-D). Re-examination of the brain MRI suggested intracranial infectious lesions (Figures 1E, F).
PMC9762491_02
Brain MRI findings of patient 2 at the diagnosis of intracranial Aspergillus infection. (A): MRI showed two lesions with diameters of 1.56 cm and 0.64 cm on POD 7. (B): MRI showed five lesions with diameters of 2.20 cm, 0.79 cm, 0.73 cm, 0.37 cm, and 0.28 cm on POD 28. (C): MRI showed two lesions with diameters of 1.81 cm and 0.69 cm on POD 65.
fimmu-13-1003254-g002.jpg
PMC9762491_02_fimmu-13-1003254-g002.jpg
f2
Brain magnetic resonance imaging (MRI) revealed two abnormal signals in the left temporal lobe and right frontal lobe, and the possibility of infection was considered (Figure 2A). After three weeks of antifungal treatment, the patient's neurological symptoms slightly improved, but re-examination of brain MRI showed that the lesion was larger than before (Figure 2B). During the following three weeks, antifungal therapy was maintained, and re-examination of the brain MRI showed that the infected lesions were smaller than before (Figure 2C).