PMC4821445_01
Endometrial adenocarcinoma (upper left) invading the cervical stromal connective tissue. Benign endocervical tissue can be seen in the lower right.
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Histologically, the anterior endometrium was involved by a grade 2 endometrioid adenocarcinoma that invaded 92% of the myometrium and extended to the cervical stromal connective tissue (Fig. 1).
(A) Low power image of leiomyosarcoma (left) adjacent to leiomyoma (right). (B) High power image showing pleomorphic spindle cells with bizarre nuclei and mitoses with atypical forms.
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Interestingly, the posterior large myometrial mass consisted of predominantly leiomyoma (Fig. 2A). However, within this mass was a region of tumor cells with bizarre pleomorphic nuclei and numerous mitoses including atypical forms (Fig. 2B).