PMC9633863_01
The tumor that has protruded from the surface is accompanied by ulceration.
fsurg-09-842054-g001.jpg
PMC9633863_01_fsurg-09-842054-g001.jpg
F1
This time, physical examination revealed a tumor (8 cm x 9 cm), which has partially protruded out from surface (5 cm x 3 cm) with ulceration (Figure 1).
Intraoperative image. (A) Appearance after surgical resection of UPS. (B) Image showing the muscle and adipose tissues exposed after expanded tumor resection.
fsurg-09-842054-g002.jpg
PMC9633863_01_fsurg-09-842054-g002.jpg
F2
The diameter of operative incision was 15 cm (Figure 2A). In the end, we performed adjacent flap transfer repair; meanwhile, vacuum sealing drainage (VSD) negative pressure closed the drainage (Figure 2B).
Histopathological features of tumor. Microscopically, numerous spindle cells are seen (x200). A and B mean the tissue sections of different parts in the mass.
fsurg-09-842054-g003.jpg
PMC9633863_01_fsurg-09-842054-g003.jpg
F3
Histopathological section showed that there are numerous spindle cells with obvious atypia and irregular nuclei; the mitotic figures were extremely common to see, and multinucleated giant cells are seen, which is consistent with UPS (Figure 3).
Immunohistochemistry staining of differentially expressed proteins in the tumor tissue. (A) Tumor cells showing positive immunoreactivity for SMA. (B) Tumor cells showing positive immunoreactivity for Ki-67 (index 70%). (C) Tumor cells showing positive immunoreactivity for Desmin. (D) Tumor cells showing no immunoreactivity for CD31 (x200). (E) Tumor cells showing no immunoreactivity for CD34 (x200). (F) Tumor cells showing no immunoreactivity for S100 (x200).
fsurg-09-842054-g004.jpg
PMC9633863_01_fsurg-09-842054-g004.jpg
F4
The tumor cells were immunohistochemically determined to be positive for SMA, Ki-67 (index 70%), and Desmin but negative for CD31, CD34, and S100 (Figure 4).