PMC5283965_01
A contrast-enhanced CT scan revealing perfusion defects (arrows) in the spleen (a), kidney (b, c) on the ninth day. The perfusion defects decreased significantly on the 29th day after treatment with unfractionated heparin (d-f).
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Abdominal contrast-enhanced CT demonstrated perfusion defects in the bilateral kidneys and spleen (Fig. 1). Two days after starting the administration of unfractionated heparin and a calcium channel antagonist, the abdominal and back pain attenuated and then subsided with the clearance of perfusion defects in bilateral kidneys and spleen on abdominal CT (Fig. 1). The serum creatinine level was elevated to 2.97 mg/dL two days after the onset, while the D-dimer was elevated to 5.9 mug/mL and LDH to 3,138 IU/L.
Clinical course. CDDP: cisplatin, VP16: etoposide, CBDCA: carboplatin, WBRT: whole brain radiation therapy, LDH: lactate dehydrogenase, Plt: platelet counts, Cre: serum creatinine
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After administering anti-coagulant therapy these data all declined to the normal ranges on the 26th day (Fig. 2).