PMC8428879_01
Annular erythematous plaques with spared centers on the chest and
upper limb.
1678-9946-rimtsp-63-S1678-9946202163068-gf01.jpg
PMC8428879_01_1678-9946-rimtsp-63-S1678-9946202163068-gf01.jpg
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During the physical examination, we found diffuse annular erythematous plaques on the chest, back, upper and lower limbs (Figure 1).
A histopathological exam showing a perivascular lymphoplasmacytic
infiltrate (HE, 40X).
1678-9946-rimtsp-63-S1678-9946202163068-gf02.jpg
PMC8428879_01_1678-9946-rimtsp-63-S1678-9946202163068-gf02.jpg
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The histopathological examination showed a dense mononuclear infiltrate in the epidermis and hypodermis, with perivascular and perianexial involvement (day 14) (Figure 2).
Anti-treponemal antibodies and spirochetes in an immunohistochemistry
test (40X, indicated by the arrows).
1678-9946-rimtsp-63-S1678-9946202163068-gf03.jpg
PMC8428879_01_1678-9946-rimtsp-63-S1678-9946202163068-gf03.jpg
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The immunohistochemistry showed the presence of anti-treponemal antibodies and numerous spirochetes (Figure 3).