PMC3615840_01
Ulceration on the dorsal aspect of the left foot: inflammatory rim around the ulceration, desquamation, and diffuse erythema.
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On dermatological examination, a round ulceration 21 mm in diameter surrounded by an inflammatory rim (Figure 1) was observed.
Proliferation of basaloid cell with palisading disposition (hematoxylin and eosin, 40x).
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Clinical aspect after therapy: xerosis, small linear erosion, desquamation.
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In regular clinical examinations, no cutaneous lesions that could possibly raise the suspicion of recurrence were observed, mild erythema and xerosis being comfortable and handled toward good evolution by emollients (Figure 3).
PMC3615840_02
The tumoral lesion at admission.
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Islands of basaloid cells with palisading disposition in the upper dermis, with contraction around them (hematoxylin and eosin, 40x).
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A punch biopsy was taken, and histopathology led to a diagnosis of basal cell carcinoma (Figure 5).
Clinical aspect after cryotherapy: no ulceration, no tumoral lesion, just a slight area of erythema.
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Cryotherapy was also applied once daily for 7 days, with ibuprofen orally when needed, without hospitalization or bandage application (Figure 6).
PMC3615840_03
A small bleeding tumor covered by crust on the nose, multiple actinic keratosis on the face.
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A 78-year-old female patient was referred to us from the otorhinolaryngology department for a basal cell carcinoma of the nose (Figure 7), confirmed by histopathological report of a previous biopsy (Figure 8).
Basal cell carcinoma: typical nuclear palisading at the peripheral layer of the tumor (hematoxylin and eosin, 100x).
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A 78-year-old female patient was referred to us from the otorhinolaryngology department for a basal cell carcinoma of the nose (Figure 7), confirmed by histopathological report of a previous biopsy (Figure 8).
Cryotherapy procedure.
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We applied 2 weeks' (one application per 2-day interval) liquid nitrogen with a cotton swab (Figure 9), through the same protocol described above, no anesthesia or other medication being necessary during the period of applications.