PMC3464076_01
Coronal T1-weighted MRI reveals thickening of the left vocal cord (black arrow).
can-6-273fig1.jpg
PMC3464076_01_can-6-273fig1.jpg
figure1
MRI scan showed soft tissue fullness in the area of the left vocal cord (Figure 1).
Histologically, the tumor is composed of spindle-shaped myofibroblasts in collagenous and inflammatory background (hematoxylin-eosin stain, original magnification x400).
can-6-273fig2.jpg
PMC3464076_01_can-6-273fig2.jpg
figure2
IPT; abundant myofibroblasts with scattered inflammatory cells were seen, cellular pleomorphism was demonstrated, and mitoses were absent. Immunohistochemically stromal cells were positive for vimentin, SMA, and calponine; CD34 and S100 were focally positive, while ALK1 staining and desmine resulted in negative reactions (Figures 2 and 3).
Reactivity in the cytoplasm of the myofibroblasts with smooth muscle actin (original magnification x400).
can-6-273fig3.jpg
PMC3464076_01_can-6-273fig3.jpg
figure3
IPT; abundant myofibroblasts with scattered inflammatory cells were seen, cellular pleomorphism was demonstrated, and mitoses were absent. Immunohistochemically stromal cells were positive for vimentin, SMA, and calponine; CD34 and S100 were focally positive, while ALK1 staining and desmine resulted in negative reactions (Figures 2 and 3).
Grossly, the tumor was firmly attached to the left true vocal cord and presented to be nodular, measuring in diameter 1.7 x 1.1 x 0.7 cm.
can-6-273fig4.jpg
PMC3464076_01_can-6-273fig4.jpg
figure4
Grossly, the tumour was firmly attached to the left true vocal cord and presented to be nodular, measuring in diameter 1.7 x 1.1 x 0.7 cm (Figure 4).