PMC3017876_01
Follicular dendritic cell sarcoma in mediastinum in 47-year-old man.. A. Unenhanced CT image of thorax reveals well-defined posterior mediastinal mass of homogeneous attenuation (white arrows) with arborizing-pattern of calcification (black arrow).. B. Contrast-enhanced CT image shows marked homogeneous enhancement of mass. Note compression of left atrium (black asterisk) and displacement of esophagus (white arrow).
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F1
An arborizing-pattern of coarse calcifications could be seen within the lesion (Fig. 1A). After the administration of intravascular contrast media, the mass showed intense homogeneous enhancement to a degree that was similar to the enhancement of the adjacent great vessels (Fig. 1B).
PMC3017876_02
Follicular dendritic cell sarcoma in upper abdomen in 28-year-old woman.. A. Image of air-barium double-contrast study shows broadening of incisura due to extrinsic compression along lesser curvature of stomach (black arrows). Overlying mucosa appears to be intact. B. Unenhanced CT image of upper abdomen shows large heterogeneous mass (white arrows) located between stomach and left lobe of liver. C. Contrast-enhanced CT image during arterial phase shows heterogeneous moderate enhancement of tumor. Note feeding arteries in periphery of tumor (black arrows). D. Portal venous phase image shows heterogeneous moderate contrast enhancement of tumor (white arrows). E. Histopathological appearance reveals that tumor is composed of spindle cells that are arranged in storiform and whorled pattern and these spindle cells are admixed with lymphocytes (Hematoxylin & Eosin stain, x 100). F. Tumor shows positive immunohistochemical staining for CD21 (paraffin immunohistochemical stain, x 100). G. T1-weighted image shows hypointense metastatic nodule in right lobe of liver (white arrow). H. Nodule is hyperintense with hypointense center on T2-weighted image (white arrow). I. T1-weighted arterial-phase contrast-enhanced image shows isointensity of nodule (white arrow) due to homogeneous enhancement. J. T1-weighted portal-phase enhanced image shows heterogeneous, mild hypointensity of nodule (white arrow).
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F2
No obvious niche sign or filling defect was detected (Fig. 2A). The lesion was generally hypodense compared with the liver and there were even lower density regions scattered within the lesion (Fig. 2B). Several prominent feeding vessels were noted in the periphery of the tumor (Fig. 2C). The mass was heterogeneously hypodense compared with the hepatic parenchyma during the portal phase (Fig. 2D). The histopathological and immunohistochemical findings (Fig. 2E, F) confirmed the diagnosis of follicular dendritic cell sarcoma. Three months after the surgery, a follow-up MRI showed a 1.7-cm nodule in the right lobe of the liver, and the nodule had low signal intensity on the T1-weighted images (Fig. 2G) and hyperintensity on the T2-weighted images with a hypointense center (Fig. 2H). T1-weighted gadolinium-enhanced images, the nodule showed homogeneous enhancement during the arterial phase, making it appear isointense compared to the surrounding normal liver (Fig. 2I). The lesion appeared slightly hypointense compared to the liver during the portal venous phase (Fig. 2J).
PMC3017876_03
Follicular dendritic cell sarcoma of cervical lymph node in 38-year-old man.. Unenhanced axial CT image reveals well-delineated homogeneous right submandibular mass that compresses adjacent structures (white arrows). Small area of mild hypodensity (black arrow) is present in mass.
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F3
The axial unenhanced CT demonstrated a 4.5-cm right submandibular mass (Fig. 3) that was displacing the right submandibular gland anteromedially, the right sternocleidomastoid muscle posterolaterally and the right carotid artery and the right internal jugular vein anteromedially.
PMC3017876_04
Follicular dendritic cell sarcoma of cervical lymph nodes in 35-year-old woman.. A, B. Enhanced CT images show multiple enlarged lymph nodes with homogenous moderate enhancement (white arrows) in left parotid gland region.
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F4
The axial contrast-enhanced CT scan of the neck (Fig. 4) demonstrated multiple masses, which were assumed to be enlarged lymph nodes, in the left parotid gland region and in the retrocervical space, and the masses ranged from 1.5 to 3 cm in diameter.