PMC4318835_01
Typical nuclear features of papillary carcinoma, including nuclear inclusions (arrows) and groves (arrowhead).
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F0001
A fine needle aspirate of the right posterior nodule was consistent with low-grade papillary cancer (Fig. 1).
18FDG-PET/CT showed focus of FDG hypermetabolism at left proximal femur.
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F0002
ACE level 14 (normal <40 microg/L), and ESR 26 (normal 0-20 mm/h). A skeletal bone survey was negative, but a positron emission tomography (PET) CT scan showed multiple hypermetabolic skeletal lesions in both humeri and the proximal left femur, and hypermetabolic hilar and mediastinal nodes (Figs. 2 and 3).
18FDG-PET/CT showed focus of FDG hypermetabolism at mediastinal lymph node.
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F0003
ACE level 14 (normal <40 microg/L), and ESR 26 (normal 0-20 mm/h). A skeletal bone survey was negative, but a positron emission tomography (PET) CT scan showed multiple hypermetabolic skeletal lesions in both humeri and the proximal left femur, and hypermetabolic hilar and mediastinal nodes (Figs. 2 and 3).
Low-power histological evaluation showed small fragments of bone marrow with a non-caseating granuloma with no evidence of malignancy (H&E, 10x).
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F0004
The pathology showed non-caseating granulomas, consistent with osseous sarcoidosis (Figs. 4 and 5).
Higher power showed a non-caseating granuloma consistent with sarcoidosis (H&E, 40x).
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F0005
The pathology showed non-caseating granulomas, consistent with osseous sarcoidosis (Figs. 4 and 5).