PMC7813654_01
CECT images of the lesion involving left kidney; a large well-defined mass is seen in left kidney which was impressing upon and displacing renal vessels
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F1
It was followed up with a contrast-enhanced computed tomography (CT) scan which showed a large well-defined mass measuring 45 x 42 x 39 mm in the left kidney which was impressing upon and displacing renal vessels (Figure 1).
A-C) histopathology of core biopsy specimen; A) tumor cells in sheets (H&E X 40); B) peri vascular arrangement of tumor cells (H&E X 100); C) tumor cells showing marked pleomorphism, irregular nuclear contours and moderate cytoplasm with interspersed giant cells (H&E X 400); D-F) resection specimen of the tumor with similar morphology; numerous hemosiderin laden macrophages are also noted signifying old hemorrhage (D- H&E X 100, E- H&E X 200, F- H&E X 400)
PAMJ-37-210-g002.jpg
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F2
Few cells showed eccentric nuclei along with few bizarre multinucleated giant cells (Figure 2).
A-D) immunohistochemical markers; A) focal membranous positivity of CD 10; B) focal membranous positivity for RCC antigen; C) diffuse cytoplasmic and membranous positivity for melan; A, D) retained nuclear expression of INI-1 (IHC X 100)
PAMJ-37-210-g003.jpg
PMC7813654_01_PAMJ-37-210-g003.jpg
F3
The immunoexpression of INI-1 was retained (Figure 3).