PMC5015502_01
Internal carotid artery wall showing alternate thinning (arrow) and thickening of the tunica media. Medial walls with fibrosis (dysplastic changes) (H and E, x40)
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F1
Medial wall changes included thickening of the wall, focal loss of the smooth muscle, and replacement with fibrosis (dysplastic change) [Figures 1-4].
Focal fence-like protrusions in the lumen of the artery (H and E, x100)
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F2
Medial wall changes included thickening of the wall, focal loss of the smooth muscle, and replacement with fibrosis (dysplastic change) [Figures 1-4].
Splitting of the internal elastic lamina (H and E, x400)
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F3
Medial wall changes included thickening of the wall, focal loss of the smooth muscle, and replacement with fibrosis (dysplastic change) [Figures 1-4].
Expansion of subendothelial loose matrix with mesenchymal cells, thickening and hyalinization of internal elastic lamina. H and E, x400
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F4
Medial wall changes included thickening of the wall, focal loss of the smooth muscle, and replacement with fibrosis (dysplastic change) [Figures 1-4].