PMC3420650_01
X-ray of right ankle joint showing submetaphyseal osteolytic lesion with sclerotic margin, seen in distal end of right tibia.
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PMC3420650_01_CRIM.PATHOLOGY2011-257458.001.jpg
fig1
Plain radiography revealed a submetaphyseal lytic lesion in the distal tibia with a sclerotic margin around it (Figure 1).
Sheets of foamy histiocytes admixed with lymphocytes and plasma cells. A necrotic bone fragment is also seen (H and E, 400x).
CRIM.PATHOLOGY2011-257458.002.jpg
PMC3420650_01_CRIM.PATHOLOGY2011-257458.002.jpg
fig2
Histopathology showed small irregular necrotic bony fragments and degenerated cartilage, surrounded by mixed inflammatory cell infiltration consisting of plenty of foamy histiocytes along with lymphocytes and plasma cells (Figure 2).