PMC6151199_01
Lymph node histology and immunohistochemistry. (a) H&E section of lymph node showing atypical follicles (arrow). (b) CD10 immunostain highlighting FL cells within atypical germinal centers (arrow). (c) BCL-2 immunostain highlighting FL cells (arrow). (d) BCL-6 immunostain highligting FL cells (arrow). (e) Higher magnification of the area of paracortical expansion by neoplastic CML cells. (f) CD15 highlighting neoplastic CML cells (arrow). (a-d) 10x objective magnification, (e) 40x objective magnification, and (f) 20x objective magnification.
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fig1
The patient subsequently underwent an excisional biopsy of the cervical lymph node, which revealed involvement with CML and FL (Figure 1).