PMC5061303_01
Axial views of a contrast enhanced CT scan of the liver revealing a large heterogenous tumour in the second and third segment of the liver, as signaled by the red arrows.
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Sagital views of a contrast enhanced CT scan of the liver revealing a large tumour in the second and third segment of the liver.
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Panel A (40x H&E Stain), B (100x H&E Stain) and C (400x H&E Stain) shows a lesion composed of fusiform cells with pleomorphic nuclei lining the sinusoids and alternating with areas of hemorrhage and necrosis. Panel D (400x CD31) shows Immunohistochemistry showing neoplastic cells positive to monoclonal antibody CD31.
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The liver biopsy was taken using Trucut, with no complications, and the final report showed a liver angiosarcoma with immuno-histochemistry positive for neoplastic cells CD31, CD34 and with p53-Vimentin greater than 90% and an index of cell proliferation (DAO) with Ki67 of 50% (Fig. 4).
Left lobe showing the cirrhotic tumour mass in Segments II and II.
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The patient was taken to open surgery where a cirrhotic, micro-nodular liver was found, without ascites, with a vascular type tumour that occupied segments II, III and IV of the liver (Fig. 5).