PMC3542295_01
Posttransplantation intraocular lymphoma.. A-C. MR images showing smooth, undulating soft-tissue lesion in iris and anterior chamber in right eye (arrows). Compared with vitreous humor, lesion is hyperintense on T1-weighted image (A), hypointense on T2-weighted image (B), and well enhanced after administration of contrast material (C). D.. Photomicrograph showing dense mononuclear large cell infiltrate, vesicular chromatic pattern, and prominent nucleoli, consistent with diffuse large B-cell lymphoma (hematoxylin-eosin; original magnification, x 20).
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T1- (Fig. 1A) and hypointense on T2-weighted images (Fig. 1B), and it was well enhanced after the administration of contrast material (Fig. 1C). The transplantation team and the ophthalmologist made a joint decision to perform enucleation, because the ocular infection was intractable to conventional therapy and the recovery of visual acuity was deemed unlikely. Routine histopathological analysis and immunohistochemical staining of the ocular mass showed an extensive mononuclear cell infiltrate with large cells and a vesicular chromatic pattern, consistent with diffuse large B-cell lymphoma (Fig. 1D).