PMC4904736_01
The ileal biopsies of the patient showed pathognomonic findings of collagenous sprue including villous atrophy with thickened collagen table (HPS, 10x).
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fig1
The duodenal and ileal histologic findings showed a collagenous sprue (CS) characterized by complete villous atrophy with increased intraepithelial lymphocytes and thickened collagen table (Figure 1).
Normal ileal mucosa 4 months following cessation of olmesartan (HPS, 10x).
CJGH2016-4837270.002.jpg
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fig2
Two months later, the symptoms had subsided and repeat endoscopy with biopsies demonstrated a complete histologic remission of the CS (Figure 2).