PMC7150727_01
(a, b) 99mTc-sestamibi dual-phase with single-photon emission computed tomography/computed tomography fused images, showing uptake within middle to inferior left lobe of the thyroid. (b, c) Ultrasonograms revealing an oval-shaped hypoechoic solid nodule (1.40 x 1.39 x 1.92 cm) at the same area.
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fig1
A 99mTc-sestamibi dual-phase fusion imaging with single-photon emission computed tomography/computed tomography (SPECT/CT) was performed, and a possible left-sided inferior parathyroid was identified (Figure 1(a)). At the same area depicted by SPECT/CT, a 1.9 cm vascularized and hypoechoic oval nodule was present and considered likely to represent a parathyroid adenoma (Figure 1(b)).
(a, b) Ultrasonograms (transverse and sagittal views), demonstrating a fairly oval-shaped solid isoechoic nodule with mixed solid and cystic components (1.38 x 1.14 x 1.36 cm) in the middle portion of the left thyroid lobe.
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Neck ultrasonography showed a 1.4 cm heterogeneous nodule and central vascularity in the middle-third of the left thyroid gland (Figures 2(a) and 2(b)).
(a) Histologic appearance of the 1.3 cm papillary carcinoma in the left thyroid lobe, demonstrating a cystic neoplasia with a papillary pattern in transition with residual thyroid normal tissue (hematoxylin-eosin stain original magnification x4). (b) Histopathological section showing typical features of papillary carcinoma: fibrovascular stalk covered with follicular cells depicting eosinophilic cytoplasm follicular cells and oval nuclei (*) with pseudoinclusions (blue arrow) (hematoxylin-eosin stain original magnification x40).
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Histological examination revealed a 1.3 x 1.2 cm mass at the left thyroid lobe consistent of PTC of classical subtype (Figure 3) and PC, 2.5 cm in widest tumor dimension, with capsular and vascular space invasion (Figure 4).
(a) Histology appearance of parathyroid carcinoma in transition with papillary thyroid carcinoma removed from the left thyroid lobe. The neoplastic cells are represented by the monomorphic cellular proliferation with discrete atypia and mitosis (hematoxylin-eosin stain original magnification x4). (b) Histopathologic section demonstrating capsular invasion and (c) vascular invasion (hematoxylin-eosin stain original magnification x10).
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Histological examination revealed a 1.3 x 1.2 cm mass at the left thyroid lobe consistent of PTC of classical subtype (Figure 3) and PC, 2.5 cm in widest tumor dimension, with capsular and vascular space invasion (Figure 4).