PMC3325739_01
Hypocellular mass composed of bland fibroblasts and myofibroblasts surrounded by abundant collagen (A). Perivascular aggregate of small lymphocytes and plasma cells (B). Scattered spindle cells positive for actin consistent with myofibroblasts (C).
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F1
No cellular atypia, necrosis, or mitoses were seen (Figure 1A and 1B). These studies showed that the spindle cells were negative for CD30, CD34, Alk-1, beta-catenin, and epithelial membrane antigen (EMA) (Figure 1C).
Coronal T2 Fatsat magnetic resonance imaging during follow-up of patient after radiation treatment. Note the slow regression of the large lesion in the right infratemporal fossa. The 1998 October scan (post-radiation scan) also depicts the pre-treatment tumor extent, since no regression of tumor size was present yet at that time.
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F2
The first post-treatment MRI scan also depicted the pre-treatment tumor extent since on this scan no reduction in size of the abnormality compared to pre-radiotherapy had occurred yet (Figure 2, 1998 October). At the latest imaging performed in February 2007, residual soft tissue changes were still present in the infratemporal fossa, but stable compared to 2003 (Figure 2).