PMC7385375_01
Right lateral thoracic radiographs of a 4-year old Siberian Husky mix with smoke inhalation injury (A) radiograph obtained on presentation and (B) radiograph performed 4 days after presentation. Progressive tracheal narrowing and progressive, ventrally dependent interstitial to alveolar pulmonary pattern are present. Diffuse interstitial to bronchial pattern is present on both studies.
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F1
Thoracic radiographs showed mild tracheal narrowing and a ventrally distributed interstitial to alveolar pulmonary pattern (Figure 1A). On day 4, thoracic radiographs were repeated (Figure 1B).
Necropsy findings of a 4-year-old Siberian Husky mix with smoke inhalation after being in a housefire. Severe, diffuse tracheal mucosal necrosis, and subsequent intraluminal tracheal obstruction can be observed (black arrows). Diffuse pulmonary parenchymal edema and diffuse deposition of particulate were described.
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F2
Predominantly the cranioventral lung lobes were heavy, wet, and dark red (Figure 2).
Histology of the respiratory tract of a 4-year-old Siberian Husky mix with smoke inhalation after being in a housefire. (A) Trachea with attenuated epithelium (+) with streaming necrotic material extending from the ulcerated mucosa (*). (B) The lumen was obstructed by necrotic tissue admixed with fibrin and black particulate matter (interpreted as soot). (C) Bronchi have similarly attenuated to ulcerated mucosa with necrotic and cellular debris within the lumen. (D) Bronchiolar smooth muscle is expanded by granular, dark brown to black pigment (interpreted as carbon particles). Alveoli are variably ruptured forming coalescing airspaces (alveolar emphysema).
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F3
Histologically the remaining tracheal mucosal surface was necrotic or attenuated (Figure 3A). The intraluminal coagulum was composed of necrotic tissue, fibrin, and black particulate matter (interpreted as soot, Figure 3B). Bronchi had similarly attenuated to necrotic epithelium with intraluminal necrotic and cellular debris (Figure 3C). Alveoli were variably hyperinflated and confluent with shortened alveolar septa with blunt, clubbed ends (alveolar emphysema, Figure 3D).