PMC5135744_01
a Dismorphic features of the patient at 7.5 years of age. Microcephaly, triangular face, high forehead, protruding low set ears, micrognathia, esotropia, epicanthus, right palpebral ptosis are shown. b Height curve of the subject. The arrow indicates the start of GH substitutive therapy
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PMC5135744_01_13039_2016_298_Fig1_HTML.jpg
Fig1
Substitutive GH therapy (0.21 mg/Kg subdivided into 6 weekly subcutaneous injections) was started and led to a satisfactory increase in height (Fig. 1b).
Magnetic resonance imaging of the hypothalamic-pituitary region. Flattened pituitary gland. a coronal view. b sagittal view
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PMC5135744_01_13039_2016_298_Fig2_HTML.jpg
Fig2
MRI of the hypothalamic-pituitary region revealed a flattened pituitary gland (Fig. 2a, b).