PMC2836274_01
A liver biopsy performed in September 2006 shows in the reticulin stain an altered architecture with enlarged hepatocytes arranged in small nodules (x400).
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PMC2836274_01_1471-230X-10-6-1.jpg
F1
On the reticulin stain a typical nodular rearrangement of the parenchyma with atrophic periportal and regenerative centrolobular plates was compatible with NRH (Figure 1).
Evolution of liver function, clinical parameters and selected parameters of haemostasis were shown. Please note the changes at the time of the switch from VKA to LMWH.
1471-230X-10-6-2.jpg
PMC2836274_01_1471-230X-10-6-2.jpg
F2
With this treatment, the factor V levels increased, D-dimers normalized and fibrinogen increased (to 6.5 g/l); this was all highly suggestive of efficient anticoagulant treatment (resumed in Figure 2).