PMC5088480_01
Baseline color fundus image (a), fluorescein angiography (b) and SD-OCT (c) of the right eye of a patient presenting DME. a At baseline, hard exudates and diffuse intraretinal fluid are seen in the perifoveal area. b At baseline, diffuse hyperfluorescence due to leakage (especially supero-temporally) and hypofluorescence due to non-perfusion (infero-temporally) are seen in the perifoveal area. c Cystoid spaces and subretinal and intraretinal fluid are seen in the foveal and perifoveal area
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PMC5088480_01_40942_2016_26_Fig2_HTML.jpg
Fig2
Unpublished data from the DME study group from the Federal University of Sao Paulo showed regression of intraretinal fluid in a 49-year-old female patient presenting DME, 4 weeks after the third injection of 0.05 ml of ziv-aflibercept 25 mg/ml (1.25 mg) (Figs. 2 and 3 a, b, c).
Color fundus image (a) fluorescein angiography (b) and SD-OCT (c) of the right eye of the same patient shown in Fig. 2. 4 weeks after the 3rd monthly injection of ziv-aflibercept. a 4 weeks after the third ziv-aflibercept injection, a decrease of intraretinal fluid and hard exudates is noticed in the perifoveal area of the right eye. b 4 weeks after the third ziv-aflibercept injection, a decrease of leakage is seen in the perifoveal area of the right eye. c 4 weeks after the third ziv-aflibercept injection, a decrease in the subretinal and intraretinal fluid is noticed
40942_2016_26_Fig3_HTML.jpg
PMC5088480_01_40942_2016_26_Fig3_HTML.jpg
Fig3
Unpublished data from the DME study group from the Federal University of Sao Paulo showed regression of intraretinal fluid in a 49-year-old female patient presenting DME, 4 weeks after the third injection of 0.05 ml of ziv-aflibercept 25 mg/ml (1.25 mg) (Figs. 2 and 3 a, b, c).