PMC10318585_01
Intracranial response to sotorasib assessed with magnetic resonance imaging. T1-weighted imaging of right parietal metastasis before (A) and after (B) 6 months of sotorasib; Fluid-attenuated inversion recovery of right parietal metastasis surrounding edema before (C) and after (D) 6 months of sotorasib; T1-weighted imaging of right frontal metastasis before (E) and after (F) 6 months of sotorasib; T1-weighted imaging of right cerebellar metastasis before (G) and after (H) 6 months of sotorasib.
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fig_1
The patient was started on sotorasib, and the brain magnetic resonance imaging (MRI) after 2 months of treatment showed stability of the cerebellar metastasis, reduction in size of the previously treated parietal right metastasis with improvement of the surrounding edema, reduction in size of the previously untreated right frontal lobe metastasis, and no appearance of new brain metastases (Fig. 1).