PMC5918120_01
Cytology of splenic fine needle aspiration at initial diagnosis showing occasional LGL.
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F1
Fine needle aspiration of the liver and spleen were performed regardless of their normal appearance and revealed normal hepatocytes and normal splenic tissue respectively; though some LGL were noted in the splenic samples (Fig. 1) which were deemed to reflect either splenic infiltration or simply blood contamination.
Cytology of bone marrow aspiration at initial diagnosis, showing LGL in a significant proportion of lymphocytes.
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F2
There was an increased proportion of marrow lymphocytes (12%; 1.7-4.9); most of which appeared to contain magenta granules similar to those in the peripheral blood (Fig. 2).