PMC7369465_01
PET-CT: Increased metabolic activity of FDG at the level of a tumor of the right adrenal gland (36 x 29 mm), possibly pheochromocytoma.
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(A, B) A - macroscopic view of multinodular solid adrenal tumor, the biggest was 41 x 32 mm. B - Photomicrograph (original magnification, x10; hematoxylin-eosin stain). Multifocal pheochromocytoma of adrenal medulla with alveolar pattern of growth (Zellballen architecture) (black arrow) and rich vascular network (blue arrow).
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Histopathological examination described multicentric, predominantly alveolar pheochromocytoma (Fig. 2A, B).
USG of the thyroid gland: right lobe with one heterogeneous node 7 mm and multiple calcinates, intronodular vascularity.
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Macroscopic view of the thyroid gland, 8 x 3 cm.
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Total thyroidectomy was performed, macroscopic examination revealed multinodular thyroid gland with dimensions 8 x 3 cm (Fig. 4).
(A, B). A - Photomicrograph (original magnification, x10; hematoxylin-eosin stain). Medullary thyroid carcinoma with trabecular pattern of growth. 1. Amyloidosis of the stroma (black arrow). 2. Plasmacytoid tumoral cells with round nuclei (blue arrow). B-Photomicrograph (original magnification, x4; (Congo red stain). Positive reaction for amyloid in tumoral stroma (black arrow).
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Histochemical investigation with Congo red for detecting amyloid deposits in the tumor stroma was positive (Fig. 5A, B).