PMC6507531_01
(A) Erythematous-vesicle-squamous-crusty lesions on palms (arrows). (B) Computed tomography chest showing bullous emphysematous lesions in both lungs (arrows).
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F1
On his palms and soles erythematous-vesicle-squamous-crusty, lesions were seen (Fig. 1A). Computed tomography findings reveal pleural thickening in the right hemithorax and bullous emphysematous lesions in both lungs, the largest measured 8 cm (Fig. 1B).
(A) Epidermal hyperkeratosis with intra- and subepidermal pustules (arrow); and histiocytes, eosinophilic infiltration of inflammatory cells containing polymorphs and congested capillaries with extravasated red blood cell (H and E, x100). (B) Positive immunohistochemistry for antigen CD1a (H and E, xCD1a, x400).
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F2
Histiocytic cells had a positive reaction with CD1a and it was consistent with the Langerhans cell histiocytosis group disease (Fig. 2A and B).