PMC3114546_01
Chest radiograph showed acute bilateral pulmonary infiltration, more confluent in the areas of the right upper and bilateral lower lobes.
CRIM2011-628743.001.jpg
PMC3114546_01_CRIM2011-628743.001.jpg
fig1
A repeat chest radiograph revealed acute wide spread pulmonary infiltrates, which represented a significant change from the prior study (Figure 1).
High resolution CT of the chest showed diffuse ground glass opacities mainly involving the upper lobes.
CRIM2011-628743.002.jpg
PMC3114546_01_CRIM2011-628743.002.jpg
fig2
High-resolution computed tomography (HRCT) of the chest revealed diffuse ground glass opacities throughout the lung fields, with bilateral traction bronchiectasis (Figure 2).
Histopathology showed diffuse alveolar damage pattern-mixed exudative and organizing phase, as demonstrated by video-assisted thoracostomy lung biopsy: showing interstitial edema and hemorrhage (A), diffuse alveolar wall thickening by proliferating connective tissue, formation of hyaline membranes, (B) and type II pneumocyte hyperplasia (C), (hematoxylin- eosin stain) (original x 100).
CRIM2011-628743.003.jpg
PMC3114546_01_CRIM2011-628743.003.jpg
fig3
The lungs revealed diffuse alveolar wall thickening with proliferating connective tissue, formation of hyaline membranes, and type II pneumocyte hyperplasia (Figure 3) compatible with DAD pattern: mixed exudative and organizing phase.