PMC8419549_01
The computed tomography chest showing multiple metastatic lesions in bilateral lung fields.
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However, CT head showed no metastases (Figures 1 & 2).
The computed tomography abdomen and pelvis showing multiple hepatic metastases.
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However, CT head showed no metastases (Figures 1 & 2).
Neoplastic cells containing round to slightly irregular nuclei with moderate amount of cytoplasm. Cells are existing in irregular interdigitating islands. There is no evidence of significant necrosis.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
Neoplastic cells with irregular nuclei and moderate amount of cytoplasm. The fibrous stroma containing scattered thin-walled ectatic vessels and well-developed collagen with fibroblast nuclei.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
Staining positive for synaptophysin.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
Staining positive for HepPar 1.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
Staining positive for cytokeratin 7.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
Staining positive for alpha-fetoprotein.
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Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).