PMC5585603_01
Preoperative computed tomography (CT) scan showing a right renal mass.
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We report the case of a 56-year-old Caucasian man presenting with a right renal mass (12 x 9 x 8 cm) revealed by CT (Figure 1) and MRI (Figure 2).
Preoperative magnetic resonance imaging (MRI) scan showing a right renal mass.
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We report the case of a 56-year-old Caucasian man presenting with a right renal mass (12 x 9 x 8 cm) revealed by CT (Figure 1) and MRI (Figure 2).
Histological findings. (a) Histological section of kidney parenchyma showing a chronic pyelonephritis characterized by the presence of interstitial fibrosis, inflammatory infiltrate of lymphocytes and plasma cells, and atrophy and dilatation of tubules that contain pink casts (hematoxylin-eosin (H-E), 10x). (b) The fibroadipose tissue of the kidney capsule typically shows the histological findings of IgG4-related disease, characterized by an irregularly whorled pattern of fibrosis (storiform fibrosis) associated with inflammatory infiltrate (H-E, 10x). (c) A vein obliterated by a transmural inflammatory cell infiltration (obliterative phlebitis) (H-E, 20x). (d) Immunostaining with anti-IgG4 antibody shows the presence of numerous positive cells (x20).
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T cells (CD20+, CD3+), as well as focal obliterative phlebitis. The IgG4+/IgG ratio was 70% (Figure 3).