PMC3184435_01
The classical "rhabdoid" morphology of the tumor comprising the cytoplasmic hyaline globules and the eccentric nucleus. Mitotic figures are also seen (H&E stain, magnification power x400).
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fig1
The tumor consisted exclusively of cells retaining the classical "rhabdoid" morphology (Figure 1).
INI1/BAF47 immunostain showing loss of nuclear staining in the rhabdoid cells in comparison to the positive nuclei of the endothelial cells (INI1/BAF47 immunohistochemical stain, magnification power x200).
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fig2
The tumor cells, in comparison to the endothelial lining of the capillaries, showed loss of INI1 (mouse monoclonal, BAF 47, ready to use; BD Transduction Laboratories, USA) nuclear staining (Figure 2).
Weak-to-moderate ER nuclear expression of the tumor cells (ER immunohistochemical stain, magnification power x400).
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fig3
Tumor cells have showed nuclear positivity to ER (mouse monoclonal, 1 : 20; Dako) (weak to moderate in 90%) (Figure 3) and have also showed nuclear positivity to PR (mouse monoclonal, 1 : 100; Dako) (strong in 20%).