PMC6722175_01
Magnetic resonance imaging. Shown is a left-sided adrenal mass (arrows) with a maximum diameter of 2.3 cm. Only slight signal loss in the opposed phase on Tl weighted-images. Mild contrast-enhancement in the periphery of the tumor. Multiple hepatic cysts. Tlw, T2w: Tl- or T2 weighted, respectively; TSE, turbo spin echo; VIBE, volumetric interpolated breath-hold examination; FS, fat saturated; KM+, with contrast agent.
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F1
An adrenal MRI demonstrated a normal looking right adrenal and a left-sided adrenal mass with a maximal diameter of 23 mm, compatible with an adrenal adenoma (Figure 1).
Immunhistochemistry. The formalin-fixed paraffin-embedded adrenal corresponding to the adenoma was stained with HE (Left) or subjected to CYP11B2 immunostaining (Right). Demonstrated is an intense CYP11B2 expression.
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F2
The expected diagnosis of an aldosterone-producing adenoma was confirmed by CYP11B2 (aldosterone synthase) immunohistochemistry (Figure 2).