PMC8075668_01
Diagram showing the evolution of patients who received organs from the donor with tuberculosis. *SPK recipient. Outcome: cured from tuberculosis. Death related to end-stage renal disease (ESRD) 2 years after transplantation.
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fig1
At that time, two recipients had already died, and a look-back investigation was carried out (Figure 1).
Images, surgical findings, and histological exams of the SPK transplant recipient: (a) caseous necrosis in the explanted kidney; (b) caseous necrosis in the mesentery; (c) nodule in the renal hilum, diffuse urothelial thickening, and compression of renal vein; (d) pancreas: collection adjacent to pancreatic graft; (e) lung endobronchial spread: "tree-in-bud"; (f) brain abscess: frontal lesion with perilesional halo of edema; (g) thyroid: increased volume, heterogeneous collection on the left lobe; (h) caseating granuloma in renal biopsy.
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fig2
The removal of the renal graft was the only viable treatment encountered (Figure 2).