PMC1557796_01
Changes in adjusted serum calcium in the index patient
from the start of imatinib treatment. Reference range 2.2-2.55 mmol/L.
SRCM2006-48948.001.jpg
PMC1557796_01_SRCM2006-48948.001.jpg
F1
On stopping imatinib, the symptoms rapidly resolved, and the serum calcium and magnesium recovered to 2.37 and 1.0 mmol/L respectively (Figure 1).
Changes in adjusted serum calcium in 17 patients
receiving imatinib for advanced GIST, shown as mean +- standard deviation. Reference range 2.2-2.55 mmol/L.
SRCM2006-48948.002.jpg
PMC1557796_01_SRCM2006-48948.002.jpg
F2
All patients exhibited a rapid and sustained fall in adjusted serum calcium during treatment with imatinib to 2.30 +- 0.08 mmol/L at 6 months (Figure 2) although few readings were below the lower limit of the normal range.