PMC3832320_01
iFISH with LSI TEL/AML1 dual fusion probe; A) iFISH detected 8 in tandem copies of
RUNX1 gene in the present case; B) Negative control for the TEL/AML1 probe showing
a normal cell
rbhh-35-05-0369-g01.jpg
PMC3832320_01_rbhh-35-05-0369-g01.jpg
f01
FISH (iFISH) analysis revealed no ETV6/RUNX1 fusion signals and 6 to 10 signals for the RUNX1 probe in 75% of the analyzed nuclei in this child (Figure 1A & 1B). FISH analyses with MLL and BCR/ABL probes showed normal results.