PMC8101652_01
Intraoral examination revealed a healthy oral mucosa.
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A - Computed tomography of the mandible (axial plane) - note a reduction of bone trabeculations in the mandibular body, possibly related to infiltration; B and C - Axial plane of MRI with bilateral mandibular bone marrow signal alteration (arrows); B - T2 high signal tissue near the right mental foramen related to the involvement of the inferior alveolar nerve (arrow); C - Confirmation of the image in T1-weighted sequence.
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No other changes were found by means of cone-beam computed tomography (Figure 2A) and clinical examination.
Intraosseous medullar biopsy of the mandible.
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The immunohistochemical profile (Figure 4) revealed positivity for BCL-6, CD-10, CD-20, C-MYC, PAX-5, and strong positivity for Ki-67, demonstrating the presence of a mature B-cell lineage, consistent with the diagnosis of BL (Figure 5).
Immunohistochemical profile, revealed positivity for BCL-6, CD-10, CD-20, C-MYC, PAX-5 and strong positivity for Ki-67.
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The immunohistochemical profile (Figure 4) revealed positivity for BCL-6, CD-10, CD-20, C-MYC, PAX-5, and strong positivity for Ki-67, demonstrating the presence of a mature B-cell lineage, consistent with the diagnosis of BL (Figure 5).