PMC8423897_01
Timeline of disease and treatment periods. OU, both eyes; OD, right eye; OS, left eye; IOL, intraocular lens; PTK, phototherapeutic keratectomy.
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F1
Based on slit lamp exam findings, it was diagnosed as band keratopathy, however, no intervention was attempted at this time (Figure 1).
Corneal topography of band keratopathy following treatment of retinoblastoma before and three months after surgery. (A-C) The corneal curvature remained stable pre and post-operation (A: three months after surgery, B: before surgery, C: the difference between a and B); (D,E) The corneal thickness decreased after the surgery (D: three months after surgery, E: before surgery, F: the difference between D and E).
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F2
The corneal topography of the right eye was evaluated with Pentacam (Oculus Optikgerate GmbH, Wetzlar, Germany) (Figure 2) and revealed a central corneal thickness of 612 mum and mean anterior keratometry of 41.1 D. The corneal curvature remained stable while the corneal thickness decreased after the surgery (Figure 2).
Anterior segment optical coherence tomography (AS-OCT) before and after surgery. (A) Before surgery, a thin band of hyperreflectivity was along with Bowman's layer. The upper right panels show the five segments (yellow lines) on the horizontal meridian. The green numbers represent the distance from the corneal vertex, the depth of the band, and the corneal thickness at the specific site, respectively; (B) one week and (C) three months after surgery, the band of hyperreflectivity disappeared.
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F3
Anterior segment optical coherence tomography (AS-OCT) showed a thin band of hyperreflectivity involving Bowman's layer with underlying shadowing (Figure 3A). AS-OCT showed the thin band of hyperreflectivity in the ablated area had disappeared, corneal transparency had improved and the corneal surface had smoothened (Figure 3B). In AS-OCT, no band of hyperreflectivity was observed in the ablated area, and the cornea remained transparent and smooth (Figure 3C).
Slit-lamp image of the cornea after surgery. The optical zone was clear and transparent after 1 week (A) and 3 months (B).
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F4
Slit-lamp examination showed improved clarity of the ablated area (Figure 4A). Slit-lamp examination showed that the clarity of the ablated area was clear (Figure 4B).