PMC10423580_01
Large scaly erythematous plaque on the right breast.
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An irregular asymptomatic plaque with a size of 5 cm x 5 cm was seen on the right breast (Figure 1).
Histological pathogenesis of the resected specimen. (A) H&E staining. (B) Immunohistochemical staining of cytokeratin 7, (C) cytokeratin 20, and (D) Ki67. Scale bar: 100 mum.
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Histopathological examination showed hyperkeratosis, parakeratosis, and epidermal pustules (Figure 2A). Immunohistochemical staining indicated negativity for cytokeratin 7 (Figure 2B) and cytokeratin 20 (Figure 2C), and positivity for Ki67 (60%) (Figure 2D).