PMC7728468_01
Data of some physical manifestations of Patient 1. (a) Onychomycosis of the thumbnail. (b) Retained deciduous teeth at 7 years. (c) Facial features at 11 years.
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Physical examination at admission revealed a polymorphic erythematous rash of the face and eyelids, dry skin with hyperpigmentation on the limbs, onychomycosis of the nails (Figure 1(a)), a dolichocephalic configuration of the head, dysmorphic face (Figure 1(c)), and multiple dental abnormalities: retention, hyperdontia, and alignment of the teeth in two rows (Figure 1(b)).
PMC7728468_02
Data of some physical manifestations of Patient 2. (a) Hypoplasia of upper teeth at 7 years. (b) Recurrent oral ulcers at 7 years. (c) Resistant to treatment dermatitis to the scalp. (d) Resistant to treatment dermatitis of the gluteal area.
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No dysmorphic features or skeletal abnormalities were noted; however on the physical examination, hypoplasia of the upper teeth and oral ulcers were observed (Figure 2(a) and 2(b)). Her dermatitis persists despite treatment and prevention (Figure 2(c) and 2(d)).