PMC8285516_01
The clinical and pathological features of the lesion on the patient's arm. (A) The skin lesion located on the patient's right distal arm in the cubital fossa before any treatment; (B) The histology revealed numerous discrete lobules of capillaries set in the dermis. The lobules themselves are composed of multiple, bland, small, capillary-sized vessels (hematoxylin and eosin staining, original magnification x40); (C) The skin lesion got significantly improved after a four-month course of treatment with imiquimod 5% cream.
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The central part had a tendency of regression, with the periphery still enlarging (Figure 1A). Small capillary-sized vessels were scattered within the lobules (Figure 1B). She then continued the application frequency, and after four months, the whole plaque was significantly improved without any side effects (Figure 1C).