PMC4475516_01
Bilateral intense arytenoid edema with fullness of the right pyriform sinus.
CRIOT2015-934926.001.jpg
PMC4475516_01_CRIOT2015-934926.001.jpg
fig1
The remaining laryngeal structures had an intense edematous appearance (Figure 1).
(a) CT scan with contrast enhancement showing a tumoral mass of the right pyriform sinus extending through the extralaryngeal region with thyroid cartilage destruction and prevertebral area involvement. (b) CT scan demonstrating multiple metastases in both lungs.
CRIOT2015-934926.002.jpg
PMC4475516_01_CRIOT2015-934926.002.jpg
fig2
Contrast-enhanced CT (Figure 2(a)) and MRI examinations demonstrated a tumoral mass at the right pyriform sinus extending through the extralaryngeal region with thyroid cartilage destruction and prevertebral area involvement. Multiple metastatic nodules were detected in both lungs with thorax CT (Figure 2(b)).
(a) Hematoxylin and eosin staining showing small cells, round to fusiform in shape with scanty cytoplasm, fine granular nuclear chromatin, and absence of nucleoli. Note the necrosis and crush artifact (original magnification x200). The tumor cells were immunoreactive for (b) pancytokeratin and (c) CD56 (original magnification x200).
CRIOT2015-934926.003.jpg
PMC4475516_01_CRIOT2015-934926.003.jpg
fig3
The tumor cells were of small size with hyperchromatic, round to oval nuclei and scanty, poorly defined cytoplasm (Figure 3(a)). The tumor cells were immunoreactive for pancytokeratin (Figure 3(b)), CD56 (Figure 3(c)), focal synaptophysin, and thyroid transcription factor- (TTF-) 1 but negative for CD20, leukocyte common antigen, and S100.