PMC9868268_01
(A) PET scan demonstrating diffuse peritoneal areas of high glucose uptake before treatment. (B) PET/CT scan revealing the decline in glucose metabolism throughout the peritoneal region after treatment.
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Due to a lack of response from the previous antibiotic treatment, the patient underwent another full-body PET-CT, which revealed elevated glucose metabolism throughout the peritoneum (standardized uptake value (SUV) max=12.57) and part of the penis (SUVmax=13.41) and massive peritoneal effusion with peritonitis, suggesting tumor or microbial infiltration ( Figure 1A ). A full-body PET-CT was performed more than one month later, which showed a decline in glucose metabolism throughout the peritoneal and penile regions; meanwhile, the ascites had completely resolved ( Figure 1B ).
The patient's ascites mNGS coverages mapped to (E. bieneusi) (DNA/RNA) (A, B).
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The sequencing results were obtained within 24 hours, which revealed E. bieneusi DNA sequence reads was 85, the RNA sequence reads was 3495,the DNA sequences covered 0.20% of the genome ( Figure 2A ), the RNA sequences covered 2.21% of the genome ( Figure 2B ).