PMC4802299_01
Gross features of the tumor at presentation.. A large mass can be observed on the lateral aspect of the right distal thigh.
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Physical examination revealed a non-tender, 10- x 6.5- x 13-cm elastic soft, mobile mass overlying the lateral aspect of the right distal thigh (Fig. 1).
Magnetic resonance imaging findings before initial surgery.. (A) An axial T1-weighted image, (B) an axial T2-weighted image, (C) and an axial T1-weighted image after intravenous gadolinium enhancement. The tumor is located in the subcutaneous tissue on the lateral side of the distal thigh.
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Gadolinium-enhanced MRI showed heterogeneous high signal intensity (Fig. 2).
Histological findings of the primary tumor (hematoxylin and eosin staining).. Proliferating capillaries are surrounded by masses of spindle-shaped cells without any cytologic atypia. (A) Scale bar: 100 mum. (B) Scale bar: 50 mum.
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Histological examination of the tumor revealed the proliferation of capillaries surrounded by masses of spindle-shaped cells without any cytologic atypia (Fig. 3).
(A) Gross findings of the recurrent tumor (arrowhead). (B) An axial T2-weighted image showing the recurrent tumor located in the subcutaneous tissue close to the location where initial surgery was performed.
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However, a rapidly enlarging recurrent tumor was observed 11 months after the operation (Fig. 4A). MRI of the tumor showed an 8- x 8-cm mass located in the subcutaneous tissue of the anterior surface of the right distal thigh (Fig. 4B).
Histological findings of the recurrent tumor (hematoxylin and eosin staining).. Significant cytologic atypia and pleomorphism can be observed. (A) Scale bar: 100 mum. (B) The tumor has a high mitotic activity (arrowhead). Scale bar: 50 mum.
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On histological examination, the tumor cells uniformly displayed significant cytologic atypia and pleomorphism, and had 40-50 mitoses per 10 high-power fields (Fig. 5).