PMC7268156_01
(a) Left axillary mass 5 x 5 cm, (b) chest radiograph reveals diffuse nodular pulmonary infiltrations, and (c) computed tomography of pulmonary arteries shows pulmonary vessels well opacified with no filling defects.
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She had a left axillary swelling of 5 x 5 cm (Figure 1(a)) which was firm, non-tender with no discharge. The chest radiograph (Figure 1(b)) revealed diffuse nodular pulmonary infiltrations. The computed tomography of the pulmonary arteries (Figure 1(c)) showed no features of pulmonary embolism.
(a) Peripheral blood film shows moderate-to-large sized blasts with bilobed nuclei and presence of faggot cells. (b) Bone marrow aspirate reveals many moderate-to-large sized blasts with prominent nucleoli, bilobed cells and faggot cells. (c) Trephine biopsy microscopy (H&E x 40) shows hypercellular marrow which comprises almost entirely of blasts. (d-f) Panel of immunohistochemical staining (40x magnifications) shows diffuse positivity of MPO, negativity for CD34 and reactive CD3 cells.
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The peripheral blood smear (Figure 2(a)) and bone marrow aspirate (Figure 2(b)) showed presence of blasts, abnormal promyelocytes and faggot cells. The trephine biopsy microscopy (Figure 2(c)) showed a hypercellular marrow which comprised almost entirely of blast population expressing myeloperoxidase (MPO) but lacking CD34 and CD3 on immunohistochemistry (Figure 2(d)-(f)).