PMC8600255_01
Diagnostic imaging and intratumoral holmium-166 microspheres treatment of a 10-year-old Jack Russell Terrier with a pituitary tumor. (A) Gadolinium-enhanced T1-weighted spin-echo MRI six months before treatment, showing a large hyperintense circumscribed pituitary mass lesion with basisphenoid bone invasion (*). L = Left, R = Right, D = Dorsal, V = Ventral. (B) Contrast-enhanced CT (2 mm interslice spacing with 0.5 mm overlap, tube current 200 mA, tube voltage 120 kV) immediately before treatment with longest tumor height and width measured. (C) During the transsphenoidal approach and after retraction of the soft palate, the tumor was visible through the mucoperiosteum. (D) The needle was placed into the tumor center and immobilized with sutures after closure of the soft palate. (E) CT of the skull shows the needle as an imaging artifact with the needle tip in the tumor center. (F) The syringe was attached to the prepositioned immobilized needle for 166HoMS administration in the tumor center. The dog was positioned on his back.
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F1
MRI (Figure 1A) showed no significant changes compared to the previous MRI and intermittent prednisone treatment was continued.