PMC6139490_01
Patient presented with systemic erythroderma with vesiculation and desquamation at admission.
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He has diffuse edematous erythroderma at scalp, bilateral upper eyelids, trunk, scrotum and extremities with vesicular rash and desquamation. (Fig. 1).
Pulmonary nodule (A) and mediastinal adenopathy (B) demonstrated in the thoracic CT scan during admission.
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A: Pathology of the nasal surgery sample which identified melanoma 8 years ago. Tissues observed under microscope (400x). B: Pathology of transthoracic needle aspiration tissue which identified pulmonary metastatic melanoma. Biopsy tissues observed under microscope (400x). C: Immunohistochemistry analysis of transthoracic needle aspiration tissue positive for S-100.
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Meanwhile, the final pathology report confirmed its positive for S-100, indicating the lesion is metastatic melanoma (Fig. 3).