PMC3961406_01
Computed tomography scan images of. (A) whole chest and (B) enlarged scan of the tumor.
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Chest computed tomography (CT) scanning revealed a nodule ~10 mm in diameter in the left lower lung (Fig. 1), but no mediastinal or hilar lymph node swelling.
Macroscopic and microscopic findings. (A) Photograph of the tumor; (B) photograph of the tumor stained with hematoxylin and eosin captured through a magnifying glass; and (C-E) various microscopic features of the tumor (magnification, x20).
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Macroscopically, the tumor was sharply demarcated from the surrounding lung tissue and ~10x10x10 mm in size (Fig. 2A).
Immunohistological staining with (A) hematoxylin and eosin, (B) anti-napsin A antibody, (C) anti-cytokeratin AE1/AE3 antibody and (D) anti-thyroid transcription factor 1 antibody (magnification, x20).
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Immunohistochemically, the surface-lining cells were positive for napsin A, cytokeratin AE1/AE3 (Fig. 3) and cytokeratin 7 (data not shown).
Lymph node metastasis of sclerosing hemangioma. (A) Photograph showing a mediastinal lymph node from the patient. Microscopic evaluation of the metastatic area with (B) hematoxylin and eosin staining and (C) staining with anti-thyroid transcription factor 1 antibody.
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TTF-1-positive (Fig. 4).