PMC6108165_01
Postcontrast MRI post-contrast with AP (a) and sagittal (b) images showing enhancing lesion extending from nasal sinus to anterior cranial fossa with frontal lobe invasion. Post-operative postcontrast MRI post-contrast shows Axial axial (c) and AP (d) views with near total resection of mass
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F1
Magnetic resonance imaging (MRI) of the brain revealed a 7.0 x 6.2 x 4.4 cm enhancing mass extending across the cribriform plate and into the right anterior cranial fossa and right nasal cavity [Figure 1]. MRI showed no evidence of recurrence with expected postoperative changes [Figure 1].
Intra-operative images delineating our designated craniotomy (a). The dysplastic appearing dura visualized once craniotomy performed (b)
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F2
Tumor was found to be pale and hypervascular with a dural breach in the low frontal plane with involvement of the superior ethmoid sinus [Figure 2].
H and E stain (a) shows carcinoma and sarcoma components, p63 stain (b) highlights the carcinoma with squamous differentiation, PAN-CK stain (c) highlights carcinoma components, vimentin (d) highlights sarcoma, and undifferentiated tumor component
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F3
S100, CK 5/6, P63, synaptophysin, chromogranin, and GFAP. Staining negative for CD99 and neurofilament [Figure 3].