PMC9124780_01
(a) Axial and (b) sagittal computed tomography scan planes, showing irregular accumulation of contrast in the penis without distant metastases (white arrows).
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F1
The patient underwent a CT scan, which showed irregular accumulation of contrast in the penis without distant metastases (Figure 1).
Cribriform tumor structures in the corpus cavernosum (HE, original magnification x40).
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F2
Immunohistochemically, the tumor cells were positive for CDX2, which is a marker of the intestinal epithelium and helps to determine the primary location of metastatic colorectal adenocarcinomas (Figures 2-5). Later, the patient complained of severe pain in his right leg, and x-ray with bone scintigraphy imaging tests showed osteolytic-type metastases, and massive bone damage with tumor masses in both legs (Figure 2).
Tumor structures near the urethra (HE, original magnification x100).
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F3
Immunohistochemically, the tumor cells were positive for CDX2, which is a marker of the intestinal epithelium and helps to determine the primary location of metastatic colorectal adenocarcinomas (Figures 2-5).
Cribriform tumor structures with dirty necrosis. Lymphovascular invasion (marked with arrows) (HE, original magnification x100).
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F4
Immunohistochemically, the tumor cells were positive for CDX2, which is a marker of the intestinal epithelium and helps to determine the primary location of metastatic colorectal adenocarcinomas (Figures 2-5).
CDX2 immunohistochemistry. Positive nuclear staining in tumor cells (original magnification x40).
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F5
Immunohistochemically, the tumor cells were positive for CDX2, which is a marker of the intestinal epithelium and helps to determine the primary location of metastatic colorectal adenocarcinomas (Figures 2-5).
Timeline of the presented case.
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F6
The patient died 3 months later (see the timeline in Figure 6).