PMC6204878_01
CT image.. Notes: (A) Infiltration of the right upper lobe of the lung before treatment. (B) Infiltration of the right upper lobe of the lung after IL-2 therapy. (C) Infiltration of the right upper lobe of lung worsened after PD-1 inhibition. (D) Infiltration of the right upper lobe of lung absorbed after 6 weeks of anti-TB treatment.. Abbreviations: CT, computed tomography; TB, tuberculosis.
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The chest computed tomography (CT) scan (Figure 1A) showed a shadow at the posterior segment of the right upper lobe of the lung. Another chest CT scan (Figure 1B), performed in March 2016, suggested a slightly reduced lesion of the right lobe of the lung. The chest CT (Figure 1C) showed the increased size of the lesion in the right upper lobe without lymphadenopathy or pleural effusion. The chest CT scan (Figure 1D) showed that the right pulmonary lesion had shrunk significantly in April 2017.
Histopathological findings of TB granuloma from the lung biopsy.. Notes: A large amount of caseous necrosis surrounded with epithelioid cells and diffused infiltrating lymphocytes (paraffin-embedded tissue by H&E staining). (A) Original magnification (20x). (B) Local magnification of (A) (400x). Solar marking: caseous necrosis; blue arrows: epithelioid cells.. Abbreviation: TB, tuberculosis.
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The transbronchial lung biopsy specimen showed a large amount of caseous necrosis (Figure 2A and B) with mediate lymphocyte infiltrate but few acid-fast bacilli. The number of