PMC212447_01
Gross photograph of the right femoral head showing a lytic lesion.
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F1
The patient was started on irradiation therapy but pain persisted and he was admitted for femoral head resection (Figure 1).
Gross photograph of the left femoral head with a similar lytic lesion.
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F2
The left femoral head was resected (Figure 2) and no prosthesis could be implanted.
Low-power photomicrograph of the femoral head showing bone destruction and infiltration by a diffuse epithelial tumor (note the presence of remaining bone trabeculae) (hematoxylin-eosin, x 100)
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F3
The histological analysis of both femoral heads confirmed the presence in the lytic areas of a diffuse proliferation of epithelial cells (figure 3), some of which corresponded to signet ring cells (Figure 4).
High-power photomicrograph of the tumor cells, showing signet ring features (PAS stain, x 400)
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F4
The histological analysis of both femoral heads confirmed the presence in the lytic areas of a diffuse proliferation of epithelial cells (figure 3), some of which corresponded to signet ring cells (Figure 4).