PMC9073112_01
MRI images showing a heterogenous well-defined right gluteal soft tissue mass (a and b) and multifocal hypointense lesions of the pelvic bones and appendicular skeleton (c) suggestive of metastatic lesions.
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TV x AP) heterogeneous well-defined, right gluteal intermuscular soft tissue mass. The visualized pelvic bones and appendicular skeleton on MRI demonstrated low signal intensity on T1-weighted images with multifocal hypointense lesions suggestive of secondary metastatic disease (Figure 1).
99mTc methylene diphosphonate (MDP) bone scintigraphy demonstrating widespread osteoblastic skeletal metastases involving the axillary and appendicular skeletal system.
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Widespread osteoblastic lesions were also identified on 99mTc methylene diphosphonate (MDP) bone scintigraphy (Figure 2).
(a) Microscopic images showing monomorphic malignant epithelial cells arranged in fused and poorly formed glands, as well as small nests (haematoxylin and eosin, 100x); (b) gland-forming cells with moderate amphophilic cytoplasm, round nuclei and distinct nucleoli (haematoxylin and eosin, 400x); and (c) NKX3.1 immunohistochemistry showing strongly diffuse nuclear expression in the neoplastic cells, associated lymphocytes and fibroblasts is negative (200x).
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A Tru-cut biopsy of the gluteal mass showed core biopsies of subcutaneous tissue demonstrating metastatic adenocarcinoma (Figure 3).