PMC8555433_01
Chest radiographic examination. (A) A mass shadow in the left lower lung field (arrow) accompanied by an infiltrative shadow in the right upper lobe (arrowhead). (B) Shrinking of the mass shadow (arrow) with the progression of the pre-existing infiltrative shadow (arrowhead).
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A 69-year-old man was referred to our hospital due to an abnormal shadow on a chest X-ray (Fig. 1A).
Chest computed tomography. (A) A lung mass in the left lower lobe (arrow). (B) An infiltrative shadow in the right upper lobe (arrowhead). (C) Shrinking of the mass shadow in the left lower lobe (arrow).
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Computed tomography (CT) showed a lung mass, 3.3 x 3.0 cm, in the left lower lobe (Fig. 2A) accompanied by an infiltrative shadow in the right upper lobe (Fig. 2B). After four cycles of the treatment, he achieved a partial response (Fig. 2C); however, after two cycles of maintenance treatment with pembrolizumab, he developed a cough, and chest X-ray revealed progression of his pre-existing infiltrative shadow in the right upper lung field (Fig. 1B).