PMC7007020_01
Dermatitis herpetiformis. Papules, vesicles and excoria tions on the knee
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f1
A 17-year-old adolescent, with no past medical history, presented to our department with itchy papulovesicles and excoriations on the elbows, knees and buttocks, occurring for the past 3 months (Figures 1 and 2).
Dermatitis herpetiformis. Papules, vesicles and excoria tions on the elbow
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f2
A 17-year-old adolescent, with no past medical history, presented to our department with itchy papulovesicles and excoriations on the elbows, knees and buttocks, occurring for the past 3 months (Figures 1 and 2).
Small neutrophilic abscesses in dermal papillae and der mo-epidermal clefts overlying the abscesses. (Hematoxylin & eosin, x100)
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f3
A second skin biopsy was obtained for histopathologic and direct immunofluorescence examinations, documenting neutrophilic abscesses in the dermal papillae and granular deposition of IgA within the dermal papillae of the perilesional skin specimen, confirming the main differential diagnosis of dermatitis herpetiformis at this stage (Figure 3).