PMC3591297_01
Skin lesion with central necrosis over right arm
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The skin rashes (Figure 1) were maculopapular erythematous, size varying from 4x5 cm to 10x8 cm without any initial itching, pain or secretion.
Skin biopsy showing dilated and congested vessels
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The axillary lymph node biopsy was suggestive of blastoid variant of mantle cell lymphoma, which showed immunopositivity for CD 20, CD43, Cyclin D1, BCL-2, BCL-6 and immunonegative for CD5, CD3, CD10, CD23. The skin biopsy from the left arm maculopapular lesion (including both healthy and affected area) showed congested vessels along with extravasations of RBC in the dermis without any atypical lymphoid cells (Figure 2a and 2b).
Skin biopsy showing extravasation RBC in the dermis
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He received R-CHOP chemotherapy and has undergone debridement (Figure 3) for the skin lesions.