PMC3498046_01
Rectal CGD seen under white light (A) and under NBI (B).
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F1
CGD-associated colitis in clinical remission for over 4 years on low-dose prednisone (5 mg per day) presented with hyperglycemia and growth delay. Colonoscopy was performed to evaluate subclinical colitis prior to a planned prednisone taper. Colonoscopy with white light revealed mild nodularity and friability in the rectum (Fig. 1A). NBI was applied the mucosal abnormalities were accentuated, creating an almost lunar appearance (Fig. 1B). NBI-targeted biopsy specimens revealed findings consistent with chronic active CGD-associated colitis.