PMC4489814_01
Marked focal corneal edema   marked focal stromal edema.. Notes: (A) Anterior segment photography showing a marked focal corneal edema. (B) Anterior segment optical coherence tomography demonstrating severe corneal swelling and markedly increased corneal thickness in the affected area. (C) Specular microscopy revealing decreased endothelial cell density and increased corneal thickness. (D) Anterior segment photography showing resolution of corneal edema through conservative management. (E) Anterior segment optical coherence tomography demonstrating complete resolution of corneal swelling. (F) Specular microscopy revealing substantially decreased endothelial cell density in the left (L) eye compared to the right (R) eye.
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A marked focal stromal edema accompanied by Descemet's membrane folds were located at 10 o'clock in the paraxial area, about 4 mm apart from the corneal center (Figure 1A). AS-OCT (AS-OCT; Carl Zeiss Meditec AG, Jena, Germany) revealed marked corneal swelling of the lesion (Figure 1B). Endothelial cell density was 1783 cells/mm2 (Figure 1C). The stromal edema resolved, showing no signs of epithelial defect, although small opacity remained (Figure 1D). AS-OCT revealed complete resolution of corneal swelling (Figure 1E). Tokyo, Japan) showed substantially decreased endothelial cell density in the lesion compared to the fellow eye (2,062 versus 2,959 mm2) (Figure 1F). The patient's condition was observed while tapering the topical steroid.