PMC3591278_01
The photo shows the massive dissemination of cutaneous lesions over the entire arm surface, appearing as confluent nodules, partially ulcerated and infected. All lesions were confined to the region of LE. The biopsy revealed the multinodular infiltration of lymphoid cells (hematoxylin and eosin staining, 40x magnification).
mjhid-5-1-e2013016f1.jpg
PMC3591278_01_mjhid-5-1-e2013016f1.jpg
f1-mjhid-5-1-e2013016
The post-transplant follow-up was uneventful for one year, when patient was again admitted to our department with a massive dissemination of purplish cutaneous nodules, in part ulcerated and infected, over the entire surface of the lymphedematous arm (Figure 1). The lesions were strictly confined to the area of chronic LE, reminding the clinical picture of the Stewart-Treves syndrome (Figure 1). The skin biopsy showed multinodular infiltration of lymphomatous cells (Figure 1) that at immunohistochemistry resulted CD20/CD5/CyclinD1positive, with a proliferative index of 90%.