PMC6363668_01
Trend of wound regression.
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F1
The trend of wound regression is plotted in Figure 1. The wound regression/time ratio reduced gradually, with a fast reduction between the first and second MSCs+CMC plasma gel applications (Figure 1). No evident exuberant scar was present after wound healing and the hair grew completely without changing color (Figure 2; Figure S1).
Images of the wound at different time points. T0: day of admission, before surgical curettage. T8: 8 days after the surgical curettage and before WJMSCs application. T12: 4 days after the first WJMSCs application (T8); granulation tissue was visible and no signs of rejection or inflammation were present. T20: after the third WJMSCs application. T24: after the last WJMSCs application. T39: day of discharge.
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F2
A granulation tissue was visible after the first MSCs application, without signs of rejection or inflammation (Figure 2). No evident exuberant scar was present after wound healing and the hair grew completely without changing color (Figure 2; Figure S1).