PMC6310926_01
Case #1 - Latero-lateral radiographic images of the front limb, presenting a critical radio-cubital bone defect. Preoperative non-union after two events of implant failure (a); Postoperative control 4 months after surgical correction using Bonelike (b); Postoperative control 8 months after surgical correction using Bonelike (c)
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Fig2
Radiographic pre- and post-surgical control was performed and it is represented in Fig. 2.
Case #2 - Latero-lateral and craniocaudal radiographic images of the hind limb, presenting a critical tibial bone defect. Preoperative non-union after internal fixation failure (a); Immediate postoperative control after surgical correction using Bonelike (b); Postoperative control 4 months after surgical correction using Bonelike (c)
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Fig3
Radiographic evaluation and clinical examination were performed in the follow-up periods (4, 8 and 12 months) to assess for the efficacy of the surgical treatments (Fig. 3).
Case #3 - Radiographic study of the mandibula presenting an oblique fracture and absence of adjacent teeth (a); Immediate postoperative control after surgical reduction by plate fixation and Bonelike  filling of the mandibular alveolar bone (b, c); Postoperative control 8 weeks after surgical correction using Bonelike (d)
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Fig4
After 8 weeks, radiographic control fracture consolidation (Fig. 4) and a very good recovery of masticatory function was described by the legal tutors.
Case #4 - Radiographic study of the mandibula presenting a mandibular fracture and absence of adjacent teeth (a); Immediate postoperative control after external fixation and Bonelike  filling of the alveolar bone defect (b); Postoperative control 5 weeks after surgical correction using Bonelike  (c)
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Fig5
The external fixation apparatus was removed uneventfully (Fig. 5).
Case #5 - Radiographic study of the maxilla evidencing the alveolar defect resulting from exodontia of the 1st pre-molar tooth before (a) and after filling on the same with Bonelike  (b)
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Fig6
No adverse reactions were detected and the patient regained appetite and normal food intake, demonstrating an excellent functional recovery (Fig. 6).
Case #6 - Visual examination of the oral cavity affected by severe periodontal disease (a); Postoperative control 6 weeks after exodontic procedure and filling of the left maxillary cavity using Bonelike  (right side of the image) (b); Visual examination of the oral cavity 6 weeks after exodontic procedure and filling of the left maxillary cavity using Bonelike (c)
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Fig7
Moreover, a mineralized consolidation of the left grafted area where it was applied the Bonelike , was confirmed through radiographic analysis (Fig. 7), while minor radiopacity was observed in the right side.
Case #7 - Visual examination of the oral cavity affected by severe periodontal disease (a); Surgical extraction of all teeth caudal to the 1st maxillary pre-molars, resulting in exposed maxillary alveolar cavities (b), that were filled with Bonelike (c) and covered by a mucosal flap (d); Postoperative control 12 weeks after exodontic procedure and filling of the defect using Bonelike  (e: right maxilla, f: left maxilla)
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Fig8
After the extraction, the alveolar bone defect was filled with Bonelike , and a mucosal flap was sutured over the bone with no tension, to occlude a patent oronasal fistula (Fig. 8).
Case #8 - Visual examination of the oral cavity and identification of the fractured canine tooth (a); Exposed maxillary alveolar cavity after tooth removal (b), that was filed with Bonelike (c) and covered by a mucosal flap (d); Postoperative control 12 weeks after exodontic procedure and filling of the defect using Bonelike (e)
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Fig9
Care was taken to ensure sufficient mobility of the mucosal flap to cover the granules (Fig. 9).
Case #9 - Visual examination of the oral cavity and identification of the fractured maxillary canine tooth (a); Exposed maxillary alveolar cavity after tooth removal that was covered by a mucosal flap (b); Preoperative control (c); Postoperative control after exodontic procedure, depicting the incomplete filling of the defect using Bonelike  (d)
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Fig10
Immediate postoperative radiographic control indicated incomplete filling of the alveolar cavity with Bonelike  (Fig. 10).
Case #10 - Visual examination of the oral cavity and the molar tooth absence (a); Postoperative control 8 weeks after surgical filling of the defect using Bonelike  (b)
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Fig11
Radiographic imaging as well as animal's behaviour and examination were unremarkable, confirming complete recovery and regeneration (Fig. 11).
Case #11 - Visual examination of the oral cavity evidencing periodontal disease and stomatitis-gingivitis complex (a); Exposed maxillary alveolar cavities after molar and premolar extraction (b), that were filed with Bonelike (c) and covered by a mucosal flap (d); Preoperative radiographic control; f: Intraoperative radiographic control after tooth extraction (e); Postoperative control 6 weeks after surgical filling of the defect using Bonelike (g); Visual examination of the oral cavity 6 weeks after surgery (h)
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Fig12
After 12 weeks, a good osteointegration was confirmed radiographically and no soft tissue nor systemic adverse reactions were detected (Fig. 12).
Case #12 -Radiographic study evidencing dental root resorption (blue arrow) (a); Small alveolar defect after premolar unilateral exodontia (b) that was filed with Bonelike  and covered by a mucosal flap (c); Postoperative control 4 weeks after surgical filling of the defect using Bonelike  (blue arrow) (d)
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Fig13
An excellent functional recovery was observed and good behaviour recuperation was described (Fig. 13).