PMC3938376_01
Erythematous and scaled plaque on the right neck
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A 72-year-old man presented erythematous and scaled plaque on the right neck for three months (Figure 1).
Histopathological features. A - Diffuse inflammatory infiltrate
consisting of neutrophils, plasma cells, lymphocytes and histiocytes in the dermis
(hematoxylin-eosin stain, original magnificationx40). B -
Cytophagocytosis of lymphocytes, neutrophils and RBCs (hematoxylin-eosin stain,
original magnificationx400). Immunopathological features. C - S-100
stains (original magnificationsx400). D - CD68 stains (original
magnificationsx400)
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The skin biopsy specimen revealed diffuse inflammatory infiltrate consisting of lymphocytes, histiocytes, sparse population of neutrophils and plasma cells in the dermis (Figure 2A). Some histiocytes contained lymphocytes, neutrophils, plasma cells and RBCs within their pale and foamy cytoplasm (Figure 2B). Immunohistochemical staining revealed that histiocytes were positive for S-100 protein and CD68, but negative for CD1a (Figures 2C e 2D).