PMC5491816_01
Colonoscopic image after induction chemotherapy, revealing multiple active ulcers in the terminal ileum (a) and entire colon (b).
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However, colonoscopy revealed multiple active ulcers in the terminal ileum and entire colon, so the prednisolone dose was further increased to 60 mg (Fig. 1).
The clinical course of the patient. All chromosomal and fluorescence in situ hybridization (FISH) analyses and percentages of blasts were analyzed using bone marrow cells. AML-MRC: acute myeloid leukemia with myelodysplasia-related changes, AraC: cytarabine, Aza: azacitidine, BMT: bone marrow transplantation, FLU: fludarabine, IDA: idarubicin, ivBU: intravenous busulfan, PSL: prednisolone
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However, chromosomal and fluorescence in situ hybridization analyses revealed the persistence of trisomy 8 (Fig. 2). AML-MRC, and chromosomal and fluorescence in situ hybridization analyses revealed complete disappearance of trisomy 8 (Fig. 2). After 4 cycles of azacitidine therapy, the patient underwent bone marrow transplantation containing 2.4x108 nucleated cells/kg from a human leukocyte antigen-matched unrelated female donor.