PMC4040033_01
Magnetic resonance imaging brain axial T2 fluid-attenuated inversion recovery (a), T1WI (c) and coronal T2WI (b) shows a well-defined hyperintense cystic lesion with few thin peripheral septation and mural nodule in right parietal region causing mass effect with midline shift to left. Note, the characteristic absence of perilesional edema. Coronal contrastenhanced T1WI (d) shows enhancement of the cyst wall (arrow heads) and mural nodule (arrow)
JPN-9-45-g001.jpg
PMC4040033_01_JPN-9-45-g001.jpg
F1
Gadolinium administration demonstrated peripheral enhancement of the lesion with strongly enhancing mural nodule [Figure 1] Based on these findings, differential diagnosis of pilocytic astrocytoma and cerebral astroblastoma were made.
Histopathological examination showing (a) Perivascular arrangement of tumor cells with short stout cytoplasmic processes anchored to blood vessel walls (H and E x 100) with strong immunopositivity to glial fibrillary acidic protein (b), vimentin (c), and S-100 (d)
JPN-9-45-g002.jpg
PMC4040033_01_JPN-9-45-g002.jpg
F2
Tumor cells were spindle shaped having moderately eosinophilic cytoplasm and eccentrically placed nuclei with strong immunopositivity to glial fibrillary acidic protein (GFAP), vimentin, and S-100 [Figure 2].