PMC5440789_01
Transverse view of the CT neck that showed presence of a neck mass measuring 28.6 mm x 18.2 mm.
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Computed tomography (CT) of the neck revealed a lobulated soft tissue mass at the level of the left side of the hyoid bone measuring 1.8 x 2.9 cm with no evidence of erosion of the hyoid bone or thyroid cartilage (Figures 1 and 2).
Axial view of the CT neck that showed presence of a neck mass measuring 25 mm in superior to inferior dimension.
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Computed tomography (CT) of the neck revealed a lobulated soft tissue mass at the level of the left side of the hyoid bone measuring 1.8 x 2.9 cm with no evidence of erosion of the hyoid bone or thyroid cartilage (Figures 1 and 2).
Central neck soft tissue demonstrating a cystic structure, within which is a proliferation of fibrovascular cores (H&E stain, 40x original magnification).
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On histologic examination, within the central neck soft tissue there is a cystic structure, within which is a proliferation of papillary fronds (Figure 3).
The cystic structure is lined by respiratory-type epithelium, consistent with thyroglossal duct cyst (H&E stain, 400x original magnification).
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The cyst is lined by respiratory-type epithelium, consistent with thyroglossal duct cyst (Figure 4), while the intraluminal proliferation, which extends into adjacent soft tissue, demonstrates complex and arborizing fibrovascular cores lined by epithelioid cells (Figure 5).
The proliferative tumor is characterized by complex and arborizing papillary fronds (H&E stain, 200x original magnification).
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The cyst is lined by respiratory-type epithelium, consistent with thyroglossal duct cyst (Figure 4), while the intraluminal proliferation, which extends into adjacent soft tissue, demonstrates complex and arborizing fibrovascular cores lined by epithelioid cells (Figure 5).
High-power view of the tumor, demonstrating cells with nuclear grooves, peripheralization of chromatin, and some prominence of nucleoli, diagnostic of papillary thyroid carcinoma (H&E stain, 400x original magnification).
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These cells are characterized by nuclear grooves with pseudoinclusions, peripheralization of nuclear chromatin, and some prominence of nucleoli (Figure 6).