PMC5677212_01
(A) Cavernous hemangiomas of the right hand, wrist, and forearm and (B) multiple enchondromas of the right hand.
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F1
On physical examination, she had several small, compressible, painless, bluish cutaneous nodules on the right hand, wrist, forearm, and shoulder, which had appeared over the past 3 years and gradually increased in volume [Fig. 1(A)]. In addition, a series of bone X-ray and magnetic resonance examinations revealed the presence of multiple enchondromas of her right hand [Fig. 1(B)], as well as enchondromas of the right scapula and left hand.
Abdominal magnetic resonance imaging showing the presence of large bilateral adrenal masses (70 mm right, 35 mm left).
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F2
Indeed, a comprehensive evaluation, including whole-body magnetic resonance imaging and extensive laboratory analyses, revealed the presence of large bilateral adrenal masses (70 mm right, 35 mm left) (Fig. 2) associated with autonomous cortisol secretion (plasma cortisol, 11.3 to 15.3 mug/dL; adrenocorticotropic hormone, <5 to <5 pg/mL; urinary free cortisol, 191 to 182 mug/d; absent circadian rhythm; positive 1-mg and 2-mg dexamethasone suppression tests).