PMC5102841_01
Chart summarizing the vital signs of the patient with anaphylaxis. Arrows indicate drug administrations: the first narrow arrow, 450 mg of pentothal sodium, 60 mg of rocuronium, and 50 microg of fentanyl; the second narrow arrow, 50 microg of fentanyl; arrowhead, palonosetron; and wide arrow, 5 mg of ephedrine twice, followed by 10 mg of ephedrine twice. Circle indicates the appearance of rash, facial edema, and conjunctival swelling with immediate administration of 4 mg of chlorpheniramine and 100 mg of hydrocortisone. sBP, systolic blood pressure; dBP, diastolic blood pressure.
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F2
As shown in Fig. 2, for general anesthesia, rocuronium, fentanyl, and sodium pentothal were administered for intubation, and desflurane was used for maintenance.
Skin test to determine hypersensitivity to palonosetron at dilutions of 1:1, 1:10, 1:100, and 1:1,000. H, control (histamine); N, control (saline). On POD 54, the sizes of wheals were as follows: histamine, 9.5 mm; saline, 2 mm; palonosetron 1:1, 13.86 mm; palonosetron 1:10, 8.5 mm; palonosetron 1:100, 9.5 mm; and palonosetron, 1:1,000, no wheal.. POD, postoperative day.
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F3
The skin test was negative on days 1 and 17, but was positive at 1:100 dilution of the allergen (0.5 microg/mL) on day 54 (Fig. 3).