PMC4318111_01
(a) Peripheral smear under oil immersion, (b) bone marrow smear showing blasts negative for myeloperoxidase. (c) Bone marrow blasts negative for periodic acid Schiff
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F1
Blasts were negative for myeloperoxidase (MPO) and periodic acid Schiff (PAS) [Figure 1] however, positive for neuron specific enolase.
Blast cells positive for t(8:21) (q22,q22) in all metaphases
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F2
On cytogenetics; blast cells were positive for t(8:21) (q22, q22) in all metaphases [Figure 2].
(a) Contrast showing isointense infiltrates to muscle; more pronounced on the right and bilateral proptosis (arrow). (b) Soft tissue density over the roof of both orbits (arrow). (c) Bilateral otitis media with mastoiditis with granulation tissue/cholesteatoma in the mastoid bone (arrow)
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F3
Contrast study of the temporal bone revealed bilateral otitis media and granulation in both of the mastoids [Figure 3].