PMC3420479_01
Slides revealed lymphocytes with deeply basophilic cytoplasm in a "starry-sky" pattern (a). The lymphoid population was CD10 (b), CD20 (c), and nearly 100% Ki-67 (d) positive.
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fig1
Nearly 100% were Ki-67 positive (Figure 1).
Staging PET scan showed a large subcutaneous defect of the left hemithorax (arrowheads). No additional involved sites were seen.
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fig2
Staging positron emission tomography/computerized tomography (PET/CT) scan demonstrated a large subcutaneous defect of the left hemithorax involving the dermis, subcutaneous tissue, and pectoral musculature, measuring 19.3 x 13.9 x 31.0 cm, with elevated [18F] fluorodeoxyglucose (FDG) uptake throughout the mass and maximal standardized uptake value (SUV) of 9.8 and an average of 6.2 (Figures 2(a) and 2(b)).
A classic BL cell seen in the bone marrow aspirate specimen (arrowhead).
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fig3
The bone marrow aspiration and biopsy showed a few scattered BL cells (Figure 3) and hybridization pattern for IgH/MYC t(8; 14).