PMC3937497_01
(a) Multiple discrete skin colored nodular lesions over back (arrow) (b) Discrete skin colored nodular lesions over face, (c) Discrete skin colored nodular lesions over back, (d) Discrete skin colored nodular lesions over posterior aspect of left thigh and leg
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F1
Mucocutaneous examination revealed multiple (20 in number), discrete, skin colored nodules, 1-2 cm in size scattered over her face, back, abdomen, thighs, and lower legs [Figure 1].
Skin biopsy showing lymphocytic infiltrate with histiocytes and giant cells [H and E, x100]
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F2
Excisional biopsy of a nodule over the trunk was done and histopathological examination revealed circumscribed large focus of diffuse dense infiltrate of large histiocytes and histiocytic giant cells with scattering of lymphocytes and a few neutrophils [Figure 2].
Skin biopsy showing multinucleated giant cells (arrow) with an amorphous eosinophilic cytoplasm [H and E, x400]
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F3
Several histiocytic giant cells resembling the Touton giant cells were also seen [Figure 3].