PMC3343453_01
Computer tomography of the patient's abdomen, transverse scan. L, left; R, right; S, very enlarged spleen; LIV, enlarged liver
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F1
There were no enlarged lymph nodes (Figure 1).
Flow cytometry in our patient: population of 77 % CD3+ T-lymphocytes are marked red on the CD 45 - SSC diagram (phenotype CD56+, CD16 partially+, CD38+, CD8 low+, CD2+, CD7+, CD5-, TdT-, CD45RO+, CD161+, intracellular granzyme B negative).
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F2
Of the additionally tested antigens, CD45RO and CD161 were positive, however the intracellular granzyme B was negative (Figure 2).
Liver histology of our patient shows lymphoma cells (arrow) between hepatocytes (star) (Haemotoxylin - Eosin stain, xi400).
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F3
The liver puncture revealed that the liver was diffusely infiltrated with lymphoma cells which were typically distributed in the sinusoids instead of in the portal tracts as seen in usual lymphomas. The nuclei of the lymphoid cells were round, ovoid, occasionally irregular with quite dense chromatin, and a small amount of pale to clear cytoplasm (Figure 3).