PMC5786569_01
Video EEG screenshots of sleep-related hypermotor epilepsy patient. (A) Bilateral hand raising, leg flexion, and moaning. (B) Yelling and abrupt sit-up. (C) Forceful lay back and bilateral pedal kicking.
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F1
Behaviors included bilateral flexing of his legs and kicking feet, flexing arms, moaning loudly, sitting up in bed, forcefully flinging back down and suddenly standing up out of bed (Figure 1; Video S1 in Supplementary Material).
Reconstructed generalized fractional anisotropy (gFA) (left) of subject with a red arrow pointing to white matter disruption with relatively lower gFA of the right frontal lobe. A tractogram overlaid on gFA (right) of the superior longitudinal fasciculus shows sparser tract density on the right compared with left side. Colors indicate fiber tract orientation, or directionality, such that green is anterior-posterior, red is left-right, and blue is superior-inferior.
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F2
However, using multishell GQI tractography, the right superior longitudinal fasciculus (SLF) was noted to be damaged, as evidence by a lesion in the image itself, as well as decreased generalized fractional anisotropy (gFA) compared with the contralateral SLF (Figures 2 and 3).
Reconstructed right and left, respectively, superior longitudinal fasciculus (SLF) tracts (above) and their corresponding average generalized fractional anisotropy (gFA) values along the tract plotted below. The gFA profile plots show lower values (circled) over the anterior segment of SLF on the right compared with left, indicating white matter tract damage.
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F3
However, using multishell GQI tractography, the right superior longitudinal fasciculus (SLF) was noted to be damaged, as evidence by a lesion in the image itself, as well as decreased generalized fractional anisotropy (gFA) compared with the contralateral SLF (Figures 2 and 3).