PMC9445419_01
Imaging of metastasizing leiomyoma. Enhanced MRI revealed soft tissue signal mass shadows in the outflow tract of the right ventricle.
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F1
Cardiac plain scan and enhanced MRI showed soft tissue signal mass shadows in the outflow tract of the right ventricle (Figure 1).
Macropathology of metastasizing leiomyoma. The leiomyoma appeared as a solid, tough, grayish-white tubercle with no exact capsule.
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On histopathologic examination, the tumor appeared as a grayish-white tubercle, with no exact capsule; it was solid and tough and measured 3 cm x 3 cm x 1.5 cm in size (Figure 2).
Histological examination (HE) of metastasizing leiomyoma. (A,B) The spindle cell tumor showed clear boundaries, mild cell morphology, fascicular arrangement, and no mitotic figures (H&E staining, A: x100, B: x400).
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Under the microscope, the spindle cells within the tumor showed clear boundaries, mild cell morphology, fascicular arrangement, and no mitotic figures (Figure 3).
Immunohistochemical (IHC) features of metastasizing leiomyoma. (Envision x 400) The spindle cells expressed desmin (A), caldesmon (B), PR (C), ER (D) and SMA (E). The calculated Ki67 labeling index was less than approximately 2% (F).
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Immunohistochemical staining for desmin, caldesmon, ER, PR and SMA was positive, and the Ki-67 index was approximately 2% (Figure 4).