PMC10455928_01
Pre- and post-treatment MRI of nasopharyngeal carcinoma and tongue cancer. (A) MRI depicting the nasopharyngeal lesion. (B) MRI showing the response of nasopharyngeal carcinoma after treatment. (C) MRI depicting the left tongue lesion. (D) MRI showing the response of tongue cancer after radiotherapy.
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The patient was diagnosed with primary non-keratinizing undifferentiated carcinoma of the nasopharynx (cT3N2M0 stage III, p63 positive) based on histopathologic and imaging findings conducted in late February of that same year ( Figures 1A ,  2 ). All malignant lesions resolved on 6 March 2014 ( Figure 1B ). A biopsy of the left tongue revealed squamous cell carcinoma (SCC) with cT2N0M0 stage II at the end of March 2019 ( Figure 1C ). May 2019. MRI scans after radiotherapy showed that the lesion on the left edge of the tongue was smaller than before radiotherapy ( Figure 1D ).
Histological images of the nasopharyngeal lesion. (A) Hematoxylin and eosin staining of primary nasopharyngectomy specimens demonstrated non-keratinizing undifferentiated carcinoma of the nasopharynx. (B) Immunohistochemical staining showed negative staining for p63. Magnifications: (A) x400; (B) x200.
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The patient was diagnosed with primary non-keratinizing undifferentiated carcinoma of the nasopharynx (cT3N2M0 stage III, p63 positive) based on histopathologic and imaging findings conducted in late February of that same year ( Figures 1A ,  2 ).