PMC9846419_01
Imaging and pathological findings of the patient. (A) On Day 7 following admission, CT showed diffuse pancreatic swelling and acute peripancreatic fluid collection. (B) A hypoechoic nodule with a size of 3.4 x 2.9 x 2.3 cm protruding into the dorsal side of the right thyroid lobe. (C)-(E) Pathological findings of parathyroid carcinoma. (C) Hematoxylin-eosin staining (x10): tumor cells within the parathyroid gland. (D) and (E) Hematoxylin-eosin staining and immunohistochemical staining of PTH (x4): tumor localized to the parathyroid gland with extension limited to soft tissue. (F)-(H) Abdominal computed tomography (CT) axial images of the patient's pancreas during the recovery period. (F) On Day 44 following admission, the percutaneous catheter drainage volume was 0 mL and the pancreatic condition was indistinguishable from inflammatory changes. (G) Three months after discharge, a pancreatic pseudocyst formed in the tail of the pancreas. (H) Six months after discharge, the exudate was almost fully absorbed.
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CT images showed newly formed acute peripancreatic fluid collection (Figure 1A). Ultrasound examination revealed a 1.2-cm hypoechoic nodule at the left lobe and a 3.4-cm hypoechoic nodule behind the right lobe (Figure 1B). Immunohistochemical staining of the carcinoma was positive for vascular endothelial growth factor (VEGF) and parathyroid hormone, negative for CD56, Galectin-3, and mesothelial cell, with a Ki-67 index of 7% (Figure 1C-E). Peripancreatic fluid was well absorbed (Figure 1F). CT images revealed a newly formed pancreatic pseudocyst and decreased peripancreatic fluid collection 3 months later (Figure 1G). The exudate was fully absorbed after 6 months (Figure 1H).