PMC10187787_01
Laboratory values (A) X-axis represents the date, the blue line represents alanine aminotransferase (ALT),the orange one represents aspartate aminotransferase (AST); (B) the blue line represents lipase, the orange one represents amylase, the patient's liver function and pancreatic enzyme levels gradually returned to normal after surgery; (C) the blue line represents platelet count, the orange one represents hemoglobin, the gray one represents plasma concentration, after 7 months of sirolimus treatment, the relationship between sirolimus concentration level and platelet count showed that the sirolimus treatment was ineffective.
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We trialed 0.08 mg/kg/day sirolimus, but the plasma concentration was maintained at only 5-5.7 ng/mL, and the platelet count remained low ( Figure 1 ).
Surgical treatment. (A) Pancreatic kaposiform hemangioendothelioma was seen during the Whipple operation (white arrow); (B) Intraoperatively, the right lobe of the liver was seen to be shrunk, and liver biopsy was rereated (white arrow).
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