PMC8384082_01
Changes in FiO2, P/F ratio (a), IL-6, CRP, D-dimer, PCT in a severe COVID-19 patient (a). Chest CT showed multiple shadows in both lungs on February 26 (b). X-ray showed multiple infiltrations in both lungs on March 01 (c). X-ray showed more severe infiltration 3 days before on March 04 (d). FiO2: fraction of inspiration O2; P/F ratio: SpO2/FiO2 ratio; IL-6: interleukin-6; CRP: C reactive protein; PCT: procalcitonin.
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Apparent chest tightness and dyspnea began to appear on February 27, 2020, with SpO2 of 80%; Chest CT showed multiple shadows in both lungs (Figure 1b); leukocyte count was 6.58 x 109/L, absolute lymphocyte count was 0.44 x 109/L and C reactive protein (CRP) was 97.3 mg/L. A chest X-ray showed progressive infiltrate and diffuse gridding shadows in both lungs (Figure 1c and d). A throat swab nucleic acid detection was negative for COVID-19 on the 9th day of hospitalization (Figure 1a).