PMC9082725_01
Consumptive coagulopathy trend for patient 1 during hospitalisation. IVIg, intravenous immunoglobulin.
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F1
The patient's coagulation parameters steadily improved over the course of 11 days on argatroban and a further two doses of 0.5 g/kg IVIg (figure 1).
PMC9082725_02
Axial slices of CT brain demonstrating (A) intraparenchymal haematoma within right temporal lobe extending into the occipital lobe with extra-axial haematoma adjacent to frontal, temporal and parietal lobes. (B, C) Axial CT venogram with images showing partial thrombosis of superior aspect of the right internal jugular vein.
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F2
CT brain demonstrated extensive right-sided temporal lobe haemorrhage with mass effect (figure 2).
Coagulopathy trend for patient 2 during hospitalisation. IVIg, intravenous immunoglobulin.
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F3
Initial pathology demonstrated evidence of a severe thrombocytopenia (platelet count of 26x109/L), markedly elevated D-dimer >20 mg/L and a low fibrinogen level at 0.9 g/L (figure 3). Significant platelet increment, rising fibrinogen and decreasing D-dimer levels were noted following IVIg (figure 3).
PMC9082725_03