PMC6939457_01
Case 1 TB specimens.. A&B: Horizontal section of right TB stained with toluidine blue showing a longitudinal fracture (Fx) involving the apical and middle turns of the cochlea and a transverse fracture involving the stapes footplate (SFP). There is an electrode tract (red *) in the scala vestibuli (SV) of the basal turn with dense new intracochlear bone (orange +) and fibrosis (>). C&D: Horizontal section of left TB stained with osmium showing a transverse fracture involving the SFP and vestibule (Vest) with new bone (blue +) and fibrous tissue (>) formation in the lateral semicircular canal (LSCC) and Vest. ME: middle ear, IAC: internal auditory canal, FN: facial nerve.
nihms-1508847-f0001.jpg
PMC6939457_01_nihms-1508847-f0001.jpg
F1
Multiple transverse fractures involve the fallopian canal (FC), internal auditory canal (IAC), stapes footplate (SFP), promontory and posterior semicircular canal (PSCC) (Figures 1A,B). The left, non-implanted, TB shows a transverse otic capsule fracture similar to that on the contralateral side (Figures 1C,D).
Case 2 TB specimens.. A: Horizontal section of left TB stained with hematoxylin and eosin showing a transverse fracture (Fx) involving the promontory. There is an electrode tract (red *) in the basal turn with dense new bone (orange +) and fibrous tissue (>). The inset shows evidence of fibrous healing adjacent to the fracture line. B: Horizontal section of right TB stained with hematoxylin and eosin showing a transverse fracture involving the spiral ligament (SL, o) of the basilar turn and internal auditory canal (IAC). There is new bone in the vestibule (Vest) and common crus (CC). FN: facial nerve.
nihms-1508847-f0002.jpg
PMC6939457_01_nihms-1508847-f0002.jpg
F2
A transverse otic capsule fracture involves the promontory and PSCC (Figure 2A) with an adjacent thin layer of fibrous tissue indicating healing fracture lines (inset). The right, non-implanted, TB shows a transverse otic capsule fracture involving the basal turn of the cochlea (Figure 2B), promontory and PSCC.