PMC3621651_01
Clinical findings at presentation and 2 weeks later. Clinical findings at presentation (A) and 2 weeks later (B). (A) At presentation, a yellowish-pink, warty mass in the right lower eyelid, close to the margin, measuring 18 x 13 x 14 mm was observed. The lesion surface had fine papillary projections with vascularity, crusting, and ulceration. (B) Two weeks later, the mass had enlarged to 20 x 14 x 14 mm.. Note: Vascularity and ulceration also expanded.
opth-7-667f1.jpg
PMC3621651_01_opth-7-667f1.jpg
f1-opth-7-667
There were no surrounding induration, madarosis, pain, and discharge (Figure 1A). The crusting, vascularity, and ulceration in the center of the lesion surface also expanded (Figure 1B).
Hematoxylin and eosin staining and Ki-67 immunohistochemical staining of the excised mass. (A) Hematoxylin and eosin staining and (B) Ki-67 immunohistochemical staining of the excised mass. Original magnification x100. (A) The lobules communicate with the epidermal surface via several openings. Each lobule is composed of a peripheral, mitotically active, basaloid germinative layer, exhibiting no cytologic atypia and maturing to vacuolated sebocytes in the center. Transitional forms are seen. (B) Ki-67 nuclear antigen is positive in 10%-15% of the sebaceous nodular cells located in the basal zone of nodule.
opth-7-667f2.jpg
PMC3621651_01_opth-7-667f2.jpg
f2-opth-7-667
Transitional cell forms were seen (Figure 2A). Immunohistochemical study detected Ki-67 in 10%-15% of the sebaceous nodular cells localized in the basal zone of the nodules (Figure 2B).