PMC7132049_01
Initial contrast-enhanced computed tomography scans of the abdomen demonstrating colon-colonic intussusception of the cecum and ascending colon.
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An abdominal and pelvic computed tomography (CT) scan demonstrated a proximal colon-colonic intussusception with appearance of a mass at the leading edge of the intussusceptum with diffuse mural thickening in the intussusceptum and the intussuscipiens with extensive mesenteric lymphadenopathy (Fig. 1).
Endoscopic findings: colonoscopy revealing large tumor-like protruding mass near the cecum.
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Colonoscopy identified a traversable, fungating, non-circumferential 10 cm cecal mass and a 15 mm pedunculated descending colon polyp (Fig. 2). Cold forceps biopsies were obtained and polypectomy was performed.
Pathological images from biopsy specimen.. A. H&E staining of biopsy specimen. (x100).. B. Cyclin D1 expression in majority of nuclei. (x100).
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Immunohistochemical (IHC) staining identified the abnormal lymphocytes to be CD20+, CD5+, BCL2+, Cyclin D1+, and SOX11+ B-cells with proliferation index of 30-40% by Ki-67+ nuclei (Fig. 3) diagnosing MCL.