PMC4896127_01
CC view from the diagnostic mammogram demonstrates two ill-defined, spiculated masses, each smaller than 1 cm. The 2 o'clock mass is posterior (short arrow) and the 4 o'clock mass is anterior (long arrow).
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The posterior mass at 2 o'clock measured 7 x 6 mm while the 4 o'clock mass measured 6 x 6 mm. (Figure 1, Figure 2).
Post-biopsy and pre-ablation sonogram demonstrates a hypoechoic, shadowing mass at 2 o'clock with a central biopsy clip (white arrow). The 4 o'clock mass had a similar sonographic appearance.
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The posterior mass at 2 o'clock measured 7 x 6 mm while the 4 o'clock mass measured 6 x 6 mm. (Figure 1, Figure 2).
6 months after cryoablation, the diagnostic mammogram CC view demonstrates similar changes at both the 2 o'clock (short arrow) and 4 o'clock (long arrow) sites. The halo of density at each site is decreased compared to the immediate post-ablation appearance. At 2 o'clock, the central mass is no longer seen, while at 4 o'clock the central mass continues to decrease in size and appears less defined.
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On the mammogram at six months post-ablation, the irregular mass at 2 o'clock was no longer seen (Figure 3).
Sonogram at 6 months after cryoablation demonstrates the 2 o'clock mass as a poorly defined hypoechoic area with a central biopsy clip (white arrow). The halo of increased density noted immediately after cryoablation has resolved.
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The hypoechoic central areas decreased in size as well at each site (Figure 4).
CC view mammogram obtained 12 months after treatment shows the central masses have resolved at both the 2 o'clock (short arrow) and 4 o'clock (long arrow) sites. There is minimal surrounding density with no architectural distortion or calcification.
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Mammogramphy one year after cryoablation showed the biopsy clips with no definite residual mass at either site (Figure 5).
Sonogram at the 2 o'clock position 12 months after cryoablation shows the site is difficult to locate except for the marker clip (white arrow). A very poorly defined area of decreased echogenicity is noted.
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Both hyperechoic rims had resolved (Figure 6).
18 months after cryoablation, the 2 o'clock (short arrow) and 4 o'clock (long arrow) sites are unchanged in appearance with no residual or recurrent mass at either site. A new 8 mm mass is present at 3 o'clock (circle).
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The mass demonstrated irregular margins (Figure 7).
Sonogram at the 2 o'clock position 18 months after cryoablation shows the biopsy clip at 2 o'clock (white arrow) with a poorly defined area of surrounding hypoechogenicity.
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The mass was hypoechoic and microlobulated, measuring 9 mm in greatest dimension (Figure 8).