PMC3177427_01
Neonatal adrenoleukodystrophy: (a) the axial T2-weighted MR image is normal; (b) the diffusion-weighted image (b = 1000 sec/mm2) reveals high-signal changes in the splenium of the corpus callosum, and occipital lobes (black arrows); (c) the ADC map reveals that the ADC values of the involved regions is low (0.69 x 10-3 mm2/sec), compared to the frontal regions (1.24 x 10-3 mm2/s).
JCIS-1-20-g002.jpg
PMC3177427_01_JCIS-1-20-g002.jpg
F1
T1- and T2-weighted sequences of the MRI examination were also normal [Figure 1a]. TE = 116 msec; the slice thickness was 5 mm. The diffusion-weighted images, obtained with a b value of 1000 sec/mm2, revealed apparent high-signal changes in the splenium of the corpus callosum, and occipital lobes [Figure 1b]. The ADC maps (which are free from T2 shine-through effects) revealed that the ADC values of the involved regions (0.69 x 10-3 mm2/sec) were low, compared to other parenchyma regions with value of 1.24 x 10-3 mm2/sec [Figure 1c].