PMC9007029_01
Lesions in the rhinopharynx in case 1 (A) and case 2 (B).
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F1
The patient presented a nonspecific lesion of the posterior wall in the rhinoparyx with an adenoid-like appearance (Figure 1B).
Nasopharyngeal tissue with numerous, diffuse non-caseating epithelioid granulomas, composed by epithelioid cells (A-D) with rare Langhans giant cells (highlighted by arrows in B) (H&E: A-B, x40; C, x100; D, x200).
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F2
We performed an endoscopic biopsy of the lesion under local anesthesia with the following histopathological report (Figure 2): similar sarcoid tissue with non-necrotizing granulomatous inflammation composed with epithelioid cells (CD68 PGM1 +) and occasional multinucleated giant cells.
PET-CT examination shows partially excavated micronodule with moderate metabolic hyperactivity (SUV 7,1 max) in the anterior segment of the left upper lobe (green arrow), concomitant with some slightly hypermetabolic lymph nodes in the bilateral and subcarinal hilar area. Presence of glucose hypermetabolism (SUV 8,7 max) in the nasopharyngeal region (white arrow).
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F3
The PET scan confirmed a higher uptake in rhinopharynx (SUV 8,7 max), oro-hypopharynx and mediastinal lymph nodes (SUV 7,1 max) compatible with the diagnosis of sarcoidosis (Figure 3).
PMC9007029_02
Lesions in the rhinopharynx in case 1 (A) and case 2 (B).
SVDLD-39-10-g001.jpg
PMC9007029_02_SVDLD-39-10-g001.jpg
F1
The patient presented a nonspecific lesion of the posterior wall in the rhinoparyx with an adenoid-like appearance (Figure 1B).