PMC6432726_01
(a) Chest radiography on admission showing bilateral ground-glass opacity, (b) discharge radiography showing improvement of ground-glass opacity, and (c) postpartum radiography showing more improvement.
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We explained the risks associated with fetal exposure to radiation to the patient, and with her consent, we acquired a chest radiograph (Figure 1(a)) and performed chest-computed tomography (Figure 2) and also conducted a respiratory function test. After high-dose steroid therapy, a chest radiograph (Figures 1(b) and 1(c)) showed improvement of radiological signs.
Chest-computed tomography on admission showing ground-glass opacity with partial honeycomb lung throughout the entire lung field.
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We explained the risks associated with fetal exposure to radiation to the patient, and with her consent, we acquired a chest radiograph (Figure 1(a)) and performed chest-computed tomography (Figure 2) and also conducted a respiratory function test.
After starting steroid therapy (prednisolone 42 mg/day), serum muscle enzyme levels were decreasing, but interstitial lung disease marker levels were increasing. So, administration of concomitant cyclosporine was started at 18 weeks of gestation. Prednisolone dose was decreased at a rate of 15%/week. She was discharged at 22 weeks and delivered at 34 weeks and 1 day of gestation.
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After starting the therapy, muscle weakness improved rapidly and serum muscle enzyme levels were decreasing (Figure 3).