PMC4896015_01
49-year-old man with metastatic GIST. Contrast enhanced axial CT scan through the liver 8 weeks after treatment with imatinib, shows two adjacent liver lesions that show cystic areas within them.
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A CT scan 8 weeks after initiation of therapy with imatinib showed that the liver metastases were reduced in size, and demonstrated cystic areas (Fig. 1A). This mass also demonstrated an intratumoral fluid-fluid level, suggesting hemorrhage (Fig. 1B). A CT scan performed at that time revealed a large hepatic subcapsular fluid collection around the right lobe, with layering of high-density material, consistent with a hematoma (Fig. 1C). A follow-up CT scan 3 months later (7 months after initiation of therapy) showed that the hematoma had nearly completely resolved (Fig. 1D).
PMC4896015_02
49-year-old man with metastatic GIST. Contrast enhanced axial CT scan through the liver at a higher level shows a tumor with internal fluid-fluid level (arrow) suggesting intratumoral hemorrhage.
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A baseline CT scan showed multiple metastatic lesions in the liver (Fig. 2A). A repeat scan five months later revealed a subcapsular hepatic hematoma (Fig. 2B) that was not as well-appreciated in the earlier scans, possibly owing to generalized intraperitoneal fluid; the hematoma was likely present the whole time.