PMC3303822_01
Top row (a) Day 0, biopsy performed: a sessile, whitish lesion of 4-5 mm in diameter is observed in the middle line of the hard palate (upper arrow). There is a violet plaque-like lesion, measuring 1 x 0.8 cm in diameter, compatible with Kaposi's sarcoma on the right side of the soft palate (lower arrow). (b) Day 3: the lesion extended causing erosion of the palatal bone. (c) Day of hospital admission and initiation of treatment (day 7): the palatal lesion extended, measuring 2 x 1 cm in diameter, presenting necrotic tissue, sulphur granules (and erosion of the palatal bone but in absence of nasal cavity fistula. Bottom row. (d) 10x view of the palatal lesion biopsy by hematoxylin eosin staining, showing actinomyces bacteria. (e) 40x magnification of the sulphur granules. (f) 40x magnification of hyphae-like actinomyces strings in the palatal specimen. Digital art disclaimer: for best identification of relevant features, images were adjusted for contrast, brightness, intensity, and saturation, but no brush strokes or similar manipulations were carried out, except for the line art arrows and letters.
CRIM2012-679728.001.jpg
PMC3303822_01_CRIM2012-679728.001.jpg
fig1
A 42-year old-subject presented with 1-week history of small, painless plaque in the middle of the hard palate, which continued growing rapidly during the following days (Figure 1).