PMC6134482_01
Interstitial granulomatous drug reaction. Papules on the (a) medial feet and (b) bilateral forearms.
10.1177_2050313X18795075-fig1.jpg
PMC6134482_01_10.1177_2050313X18795075-fig1.jpg
fig1-2050313X18795075
On physical exam, the patient had erythematous, infiltrated papules and plaques on the forearms and tender, erythematous dusky papules and plaques along the medial aspect of the feet (Figure 1).
Interstitial granulomatous drug reaction. Pathology demonstrates diffuse interstitial granulomatous infiltrates consisting of histiocytes amid thickened collagen accompanied by eosinophils (H&E, (a) x5 original magnification and (b) x10 original magnification).
10.1177_2050313X18795075-fig2.jpg
PMC6134482_01_10.1177_2050313X18795075-fig2.jpg
fig2-2050313X18795075
Features were consistent with IGDR (Figure 2).
Interstitial granulomatous drug reaction. Papules and plaques on bilateral thighs.
10.1177_2050313X18795075-fig3.jpg
PMC6134482_01_10.1177_2050313X18795075-fig3.jpg
fig3-2050313X18795075
She subsequently developed new lesions on her thighs (Figure 3), but denied any joint pain.