PMC5521080_01
76 years old female proband with facial angiofibromas
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Fig1
On closer examination by the geneticist, these papules were diagnosed as facial angiofibromas (Fig. 1).
Pedigree- the black arrow indicates the proband. The symbol * denoted individuals who underwent genetic testing for MEN1. The symbol + denotes individuals who intend to get tested in the upcoming year
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Fig2
Her family history was significant for two daughters with MEN1 diagnosed at 48 and 53 years of age and a son with hypercalcemia and elevated parathyroid hormone levels (Fig. 2).
Axial venous phase MRI showing an enhancing 1.5 cm cystic mass consistent with pancreatic neuroendocrine tumor in the tail of the pancreas (red arrow)
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Fig3
The imaging revealed an solitary enhancing, partially cystic pancreatic tail lesion suggestive of a neuroendocrine tumor (Fig. 3) measuring 1.1 x 1.3 x 1.5 cm.