PMC6354150_01
Clinical course after mercury intoxication. The chelating agent (RS)-2,3-bis(sulfanyl) propane-1-sulfonic acid (DMPS) was given enterally and parenterally for elimination. Black line: peripheral blood (left y axis, EDTA whole blood), red line: urine (left y axis), green line: stool (right y axis). Hg: hydrargium/mercury, MV: mechanical ventilation.
CRICC2019-4275918.001.jpg
PMC6354150_01_CRICC2019-4275918.001.jpg
fig1
While levels of many other compounds tested were normal, mercury levels were exceedingly high in peripheral blood (4255 mug/l, Figure 1, Table 1). This resulted in a strong reduction of mercury levels over time (Figure 1). He was also successfully weaned from mechanical ventilation and hemodialysis (Figure 1).
Autopsy result. Picture of the medulla oblongata, the cerebellum, and parts of the cerebrum as seen from caudal. The veins are very prominent, and the superficial structures especially of the cerebellum and the pons (dashed line) show marked atrophy, which is a classic late sign of mercury intoxication.
CRICC2019-4275918.002.jpg
PMC6354150_01_CRICC2019-4275918.002.jpg
fig2
Autopsy revealed severe atrophy of cerebellum, pons, and medulla oblongata (Figure 2), findings that are common after severe mercury intoxication.