PMC4357672_01
a Color fundus photograph OD demonstrating a nasal peripapillary neovascular membrane with an extension of blood and fluid into the fovea (short arrow). b The corresponding autofluorescent photograph depicts ONHD (long arrow).
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F1
The fundus examination revealed peripapillary CNV (fig. 1) with fluid tracking toward the macula. B-scan ultrasonography and autofluorescent photography confirmed the presence of ONHD (fig. 1).
Macular OCT demonstrating subfoveal fluid and pigment epithelial detachment at initial presentation (a) and subsequent response to ranibizumab (b-d) and aflibercept injections (e-h). Ranibizumab injections were administered at weeks 0, 5, and 10. Aflibercept injections were administered at weeks 15, 25, and 31. OCT images are labeled with corresponding dates.
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F2
Ocular coherence tomography (OCT) demonstrated subfoveal fluid (fig. 2). Subsequent treatment with a single aflibercept injection resulted in complete resolution of subfoveal fluid (fig. 2) and an improvement of the patient's BCVA to 20/30 OD. Two additional maintenance aflibercept injections were given during the next 3 months (fig. 2).