PMC6815633_01
Colonoscopy showing condylomatous changes in the rectum and severe diffuse punctate ulcerations and erythema involving the entire colon.
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fig1
Given severity of bloody diarrhea, a colonoscopy was performed which revealed condylomatous changes in the rectum and severe diffuse punctate ulcerations and erythema involving the entire colon but worse in the left colon (Figures 1(a) and 1(b)).
Hematoxylin and Eosin stain. Light microscopy of colonic biopsy specimens revealed intestinal spirochetes with nonspecific colitis in the entire colon and rectum.
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fig2
Light microscopy with Hematoxylin and Eosin staining of colonic biopsy specimens revealed intestinal spirochetes with non-specific colitis in the entire colon and rectum (Figure 2).
Treponemal Pallidum Immunostain. Spirochetes (red band) forming a false brush border over surface epithelium.
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fig3
Treponemal pallidum immunostaining showed spirochetes forming a false brush border appearance over surface epithelium (Figure 3).