PMC4207573_01
Fundus photograph (A) at presentation demonstrates stable findings following macular translocation for age-related macular degeneration, with geographic atrophy along the inferior arcades and no visible heme, fluid, or exudates. Early (B) and mid-phase (C) fluorescein angiograms at presentation demonstrate a small leaking juxtafoveal choroidal neovascularization lesion (orange arrow). A window defect corresponding to the inferior atrophy is also noted. No ophthalmoscopic evidence for active choroidal neovascularization is visible (orange arrow, A).
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Her fundus examination demonstrated geographic atrophy along the inferior arcade, consistent with prior macular translocation surgery, without any ophthalmoscopically visible heme, fluid, or exudates (Figure 1). Fluorescein angiography demonstrated leakage consistent with CNV (Figure 1), and optical coherence tomography (OCT) imaging demonstrated a subretinal CNV lesion without associated fluid (Figure 2).
Horizontal (left column) and vertical (right column) individual B-scan images from indicated time points.. Notes: At the patient's stable visit 3 months prior to presentation (A, B), her fovea is intact without evidence of neovascularization. At presentation (C, D), a new subfoveal choroidal neovascularization lesion is identified. No appreciable change is noted after a single bevacizumab injection (month 1) (E, F), but progressive shrinkage of the choroidal neovascularization lesion with visual improvement to baseline is noted at month 4 (G, H) and month 7 (I, J), following aflibercept treatment.. Abbreviations: BCVA, best-corrected visual acuity; s/p, status post.
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Fluorescein angiography demonstrated leakage consistent with CNV (Figure 1), and optical coherence tomography (OCT) imaging demonstrated a subretinal CNV lesion without associated fluid (Figure 2).