PMC6174758_01
Computed tomography of the chest demonstrating pericardial effusion.
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Patient was sent for CT scan to evaluate for pulmonary embolism, and a moderate pericardial effusion was found (Figure 1).
Echocardiogram demonstrating a large circumferential effusion (outlined) concerning for impending tamponade.
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Subsequently, an echocardiogram was done to further delineate the effusion which revealed a large circumferential effusion with mild respiratory variation concerning for impending cardiac tamponade (Figure 2).
Histopathology remarkable for monoclonal B-cells with significant large cell components.
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Flow cytometry of the pericardial fluid revealed a population of monoclonal B-cells with significant large cell component (Figure 3).
Fluorescence in situ hybridization demonstrating t(8; 14). This translocation is between IGH on chromasome 8 and MYC on chromosome 14.
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B-cell lymphoma with t(8; 14) (Figure 4). Bone marrow biopsy demonstrated monotypic B-cells compatible with the diagnosis of large B-cell lymphoma.