PMC5437989_01
a: Light microscopy images from the first renal biopsy specimen showing mesangial proliferation with fibrocellular crescent formation. b: Immunofluorescence microscopy images showing coarse granular deposits of immunoglobulin A (3+).
CNCS-1-014-01.jpg
PMC5437989_01_CNCS-1-014-01.jpg
Figure1
Light microscopy analysis of the initial renal biopsy specimen revealed diffuse mesangial proliferative glomerulonephritis with fibrocellular crescents in 4 of 13 glomeruli (Figure 1a). Immunofluorescence revealed granular deposits of IgA (3+) and C3 (1+) in the mesangial areas (Figure 1b), and electron microscopy revealed paramesangial electron-dense deposits.
a: Light microscopy images from the third renal biopsy specimen showing minor glomerular abnormalities. b: Electron microscopy images from the third renal biopsy specimen showing numerous myelin-like bodies in podocytes (arrow).
CNCS-1-014-02.jpg
PMC5437989_01_CNCS-1-014-02.jpg
Figure2
Light microscopy analysis of the third renal biopsy specimen revealed minor glomerular abnormalities (Figure 2a). IgA (2+) in the mesangial areas, and electron microscopy revealed paramesangial electron-dense deposits. In addition, numerous myelin-like bodies were first observed in podocytes (Figure 2b).