PMC6348892_01
FNA cytology showing benign mesothelial cells (white arrow) and hemosiderin-laden macrophages (black arrow).
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fig1
FNA cytology revealed a moderately cellular aspirate with no identifiable malignant cells (Figure 1).
CT abdomen pelvis performed after EUS-FNA aspiration showing persistence of the cyst (arrow).
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fig2
EUS guided needle based confocal laser endomicroscopy reveals clusters of cells (blue arrow) with surrounding areas of fibrosis (orange arrow) and vascularity (black arrow).
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fig3
Around-3-minute-long video was acquired with permissible needle angulation. nCLE revealed thick cord like and dark nest like structures (Figures 3 and 4).
Histology showed a mass composed of trabeculae and solid nests of round, monotonous cells with crowded nuclei and stippled, open chromatin consistent with a cystic well-differentiated neuroendocrine tumor. Few mitotic figures were identified within the tumor.
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fig4
Around-3-minute-long video was acquired with permissible needle angulation. nCLE revealed thick cord like and dark nest like structures (Figures 3 and 4). Final histopathology (Figures 4 and 5) confirmed the preoperative nCLE based diagnosis of the cystic neuroendocrine tumor of the pancreas.
Histology showed a mass composed of trabeculae and solid nests of round, monotonous cells with crowded nuclei and stippled, open chromatin consistent with a cystic well-differentiated neuroendocrine tumor. Few mitotic figures were identified within the tumor.
CRIGM2019-5187874.005.jpg
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fig5
Final histopathology (Figures 4 and 5) confirmed the preoperative nCLE based diagnosis of the cystic neuroendocrine tumor of the pancreas.