PMC10173821_01
Breast ultrasound. Hypoechoic, well defined, and encapsulated lesion. BIRADS category E4a
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F1
She performed a bilateral ultrasound (US) examination that demonstrated, as reported by the patient on the clinical mass, a 15 mm well-defined hypoechoic and encapsulated nodule with a small cystic areas inside, to the lower internal quadrant of the breast [Figure 1].
P63 (x10) - stained sections of specimen obtained with core-needle biopsy show multiple foci of high grade (G3) ductal carcinoma in situ
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F2
The lump fell under the category of Breast Imaging Reporting and Data System 4a: hence the patient subsequently had a US-guided core needle biopsy that demonstrated multiple foci of high-grade (G3) ductal carcinoma in situ arising on FA [Figure 2].
Ultrasound-guided 14G core needle biopsy of the mass
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F3
We performed three specimens with a 14G needle, no complications or bleeding were observed [Figure 3].
Hematoxylin and eosin (x20) - stained sections of specimen show an invasive breast cancer
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F4
IDC [Figure 4]. Infiltrating tumor cells showed high-grade nuclear atypia and a solid growth pattern with a necrotic area.
Hematoxylin and eosin (x20) - stained sections of specimen show lymph node metastases
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F5