PMC5440791_01
Chest X-ray on initial presentation.
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Initial chest X-ray showed bilateral diffuse peribronchial cuffing and nodular opacities with concerns for severe bronchiolitis/bronchopneumonia (Figure 1).
Trichrome stain showing global glomerulosclerosis.
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We proceeded with a renal biopsy to ascertain a tissue diagnosis for the glomerulonephritis. 12 glomeruli were available for light microscopic examination. 9/12 glomeruli showed global sclerosis (Figure 2).
Glomerulus showing intraglomerular sclerosis.
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Remaining glomeruli showed cellular to fibrocellular crescents (Figure 3).
Immunofluorescence showing linear IgG deposits.
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Immunofluorescence showed intense linear glomerular capillary staining with IgG, Kappa, and lambda chains (Figure 4).