PMC9302543_01
Clinical manifestations of the patient's hands, feet, nails and skin: incomplete and deformed nails, skin scar.
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F1
Incomplete and deformed nails on hands and feet were observed (Figure 1).
Esophagus barium swallow test: the proximal part of the esophagus appeared severely narrowed at the level of the C6 vertebral body, and the esophageal lumen proximal to the stenosis was significantly dilated.
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F2
He was investigated with a barium swallow test (Figure 2) and electronic laryngoscopy (Figure 3), which demonstrated a severely narrowed hypopharynx-esophageal entrance.
Electronic fiberoptic laryngoscopy: saliva accumulated in the hypopharynx, with thickened mucosa behind the scoop.
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F3
He was investigated with a barium swallow test (Figure 2) and electronic laryngoscopy (Figure 3), which demonstrated a severely narrowed hypopharynx-esophageal entrance.
Esophageal mucosa showed squamous epithelial shedding and proliferation of submucosal granulation tissue (HE x400 and CK immunocytochemistry x400).
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F4
Biopsies were taken from the strictured esophagus, which showed squamous epithelial shedding and proliferation of submucosal granulation tissue (Figure 4).