PMC5548676_01
A biopsy of the recurred lesion showed features of mesenchymal chondrosarcoma. (A) Mesenchymal chondrosarcoma with chondroid areas (right), Hematoxylin and Eosin (H&E) staining, original magnification 100x. (B) Mesenchymal chondrosarcoma with undifferentiated small round cells, H&E staining, original magnification 200x. (C) Undifferentiated small round cells and cartilage differentiation, H&E staining, original magnification 1,000x.
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She had undergone surgery for mesenchymal chondrosarcoma of the left femur five years earlier, with a recurred lesion three years thereafter (Fig. 1).
Chest X-ray image showing multiple spherical lesions in both lungs.
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Chest X-ray imaging revealed multiple spherical lesions in both lungs (Fig. 2), and computed tomography revealed multiple calcific metastatic lesions in the lungs, pancreas, left atrium, and pulmonary vein (Fig. 3).
Serial follow-up measurements of the patient's calcium and inorganic phosphate levels.
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Follow-up laboratory analyses revealed elevated total and ionized calcium levels, which correlated with the chemotherapy, rather than calcium replacement (Fig. 4).