PMC6746544_01
(a) Axial diffusion-weighted image (DWI) sequences show diffusion restriction of water molecules along the bilateral caudate and gyriform cortical-restricted diffusion in the bilateral cerebral hemispheres. (b) Axial fluid-attenuated inversion-recovery (FLAIR) images sequences show discrete areas of hypersignal in bilaterally caudate nuclei, as well as in the cortical regions.
kprn-13-01-1648985-g001.jpg
PMC6746544_01_kprn-13-01-1648985-g001.jpg
F0001
Diffusion-weighted brain MRI showed cortical gyriform restriction on both hemispheres and on both caudate nuclei (Figure 1).
Electroencephalography (EEG) showing periodic sharp wave complexes (PSWC) every 1 s. There is also severe disorganization of the base rhythms, which are composed of irregular and diffuse slow activities.
kprn-13-01-1648985-g002.jpg
PMC6746544_01_kprn-13-01-1648985-g002.jpg
F0002
EEG showed 1 Hz triphasic periodic sharp wave complexes (PSWC) (Figure 2) and CSF 14-3-3 protein level was elevated (77,849 AU/mL; reference value: <20,000 AU/mL).