PMC5828340_01
Brain MRI imaging. (a) Baseline coronal MPR sequences. (b) One-year follow-up coronal MPR sequences: periventricular white matter hypointensity (red arrows). Slight narrowing of cortical gyri on the vertex with enlarged Sylvian fissure. (c) Baseline Axial T2-weighted sequences. (d) One-year follow-up axial T2-weighted sequences: increased periventricular white matter hyperintensity (red arrows).
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A brain MRI revealed mild prominence of the ventricular system and cortical sulci along with multiple foci of periventricular, subcortical, and brainstem T2/FLAIR hyperintensities, consistent with chronic nonspecific microvascular changes (Figure 1). In considering the possibility of iNPH, we ordered a repeat brain MRI (Figure 1). Gait profile and neuropsychological assessment were repeated according to the same baseline procedures approximately two and six months after shunt placement (Figure 3 and Table 1).
One-year follow-up brain MRI, sagittal T2 section. A strong flow void artifact is noted at the Sylvian aqueduct.
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On sagittal sections, a strong flow void was noted at the cerebral aqueduct (Figure 2).
Video gait analysis at distance of 18 m.
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Both parameters significantly improved compared to her pre-LP condition (Figure 3). Gait profile and neuropsychological assessment were repeated according to the same baseline procedures approximately two and six months after shunt placement (Figure 3 and Table 1).