PMC4089941_01
Wright-Giemsa stain of the bone marrow aspirate demonstrating more than 50% of morphologically variable plasma cells including binucleate forms (black arrows), mature plasma cells with large basophilic cytoplasm, eccentric nucleus with perinuclear halo and clock face chromatin (orange arrows), and immature cells with high nuclear-cytoplasm ratio and dispersed chromatin (red arrows).
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fig1
Bone marrow biopsy was performed; Wright Giemsa staining of the bone marrow aspirate demonstrated more than 50% of morphologically variable plasma cells characteristic of MM (Figure 1), and immunohistochemistry confirmed lambda LC restricted plasma cells (Figure 2).
Immunohistochemistry of the bone marrow biopsy showing positivity for lambda light chains.
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fig2
Bone marrow biopsy was performed; Wright Giemsa staining of the bone marrow aspirate demonstrated more than 50% of morphologically variable plasma cells characteristic of MM (Figure 1), and immunohistochemistry confirmed lambda LC restricted plasma cells (Figure 2).
Serum creatinine trend over the course of the hospitalization.
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fig3
SCr and SFLC concentration after two doses of bortezomib and five days of dexamethasone (Figure 3). She was discharged home with an outpatient chemotherapy arrangement.