PMC8795080_01
A slit-lamp examination showing conjunctival hyperemia and anterior chamber cells in the right eye (A) and left eye (B). A fundus photograph of the right eye showing vitreous opacity (C). Fluorescein angiography of the right eye showing vascular leakage (D).
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F1
A slit-lamp examination demonstrated conjunctival hyperemia and anterior chamber cells in both eyes (Figures 1A,B). Fundus examination revealed mild vitreous opacity in the right eye (Figure 1C), but no vitreous opacity in the left eye. Furthermore, fluorescein angiography revealed retinal vasculitis in the right eye (Figure 1D).
Radiography showing bone erosions of the wrist joint (red arrow) (image of right hand).
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F2
Radiography showed bone erosions in both wrist joints (Figure 2).
A slit-lamp examination showing corneal infiltration lesion, anterior chamber cells, posterior iris synechia, and anterior subcapsular cataract in the right eye (A) and corneal infiltration lesion in the left eye (B). A fundus photograph showing vitreous opacity in the right eye (C) and left eye (D). OCT of the right eye showing serous retinal detachment (E).
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F3
Furthermore, anterior chamber cells, posterior iris synechia, and anterior subcapsular cataract were observed in the right eye, while no anterior chamber cells were seen in the left eye (Figures 3A,B). Fundus examination revealed vitreous opacity in both eyes (Figures 3C,D), and OCT revealed serous retinal detachment in the right eye (Figure 3E).
A slit-lamp examination showing improvement of the corneal infiltrative lesions and the anterior chamber cells in the right eye (A) and left eye (B). A fundus photograph showing improvement of vitreous opacity in both eyes (C) and (D). OCT showing disappearance of serous retinal detachment in the right eye (E).
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F4
Three months after the initiation of oral baricitinib, his CRP levels decreased to 0.26 mg/dL, and the corneal infiltrative lesions, as well as the anterior chamber cells, improved (Figures 4A,B). Moreover, systemic arthritis and vitreous opacity in both eyes improved (Figures 4C,D). OCT revealed that serous retinal detachment in the right eye had disappeared (Figure 4E).