PMC5346923_01
a Muddy dark blue to black pigmentation on the dorsal hands. b Black to blue patches on the anterior shins, ankles, and dorsal feet.
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f1
a Fontana-Masson stain highlighting dermal melanophages engulfing melanin. b Prussian Blue stain showing iron deposition. The combination of dermal pigmentation staining positive for both melanin and iron deposition is consistent with minocycline deposition. Original magnification x400 (a and b).
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f3
Upon consultation to dermatology, a skin biopsy confirmed dermal pigmentation consistent with minocycline (Fig. 3).