PMC9439647_01
(A-E) Plasma levels of cytokines are elevated in VSA group compared to ST group.
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On admission, ECG demonstrated ST-segment elevation and Q-wave myocardial infarction and grade III atrioventricular block (Supplementary Figure 2).
(A-C) Plasma levels of cytokines are elevated in VSA group compared to CON group.
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Coronary angiography revealed severe local stenosis of the right coronary artery, which resolved after nitroglycerine injection (Supplementary Figure 3).
(A and B) Plasma vasoconstrictor metabolites are increased in both VSA and ST group.
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Plasma cytokine assays showed that concentrations of IL-8, TNF-alpha, and soluble suppression of tumorigenesis-2 (sST2) were significantly elevated (0.15 ng/mL, 0.03 ng/mL, and 80 ng/mL, respectively). 18F-FDG PET/CT revealed a diffuse FDG uptake increase in the coronary artery and the left ventricle (Supplementary Figure 4).
PMC9439647_02
(A-D). ROC analysis of cytokines with significant differences distinguishing VSA group from ST and CON group.
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Holter ECG monitoring (Supplementary Figure 5). Her troponin I level was 11.02 ng/mL.