PMC10175592_01
Transverse MRI images performed on day 4 of hospitalization (A-D) and at recheck 130 days later (E-H). The images are at the level of the thalamus. T2-weighted (A, E), T2 FLAIR (B, F), T1-weighted pre- (C, G), and post- (D, H) administration of intravenous gadolinium. Note the bilateral symmetric T2W and T2-FLAIR hyperintense [arrow in (A, E)], T1 hypointense non-contrast enhancing lesions present within the thalamus. The lesion was markedly reduced in size at follow-up MRI with the same MRI characteristics.
fvets-10-1146091-g0001.jpg
PMC10175592_01_fvets-10-1146091-g0001.jpg
F1
MRI and CSF analysis. MRI showed a bilaterally symmetric T2W/T2-FLAIR hyperintense/T1 hypointense non-contrast enhancing lesion within the thalamus and to a lesser extent the caudal aspect of the caudate nuclei, rostral cerebral peduncles, and claustrum (see Figure 1). T2/T2 FLAIR hyperintense/T1 hypo- to isointense non-contrast enhancing lesion of the thalamus, that appeared moderately reduced in size and intensity, and no longer affected the midbrain, which was consistent with resolving myelinolysis. The lesions within the caudate nuclei, rostral cerebral peduncles, and claustrum were less evident (see Figures 1-3).
Parasagittal MRI images performed on day 4 of hospitalization (A-C) and at recheck 130 days later (D-F). T2-weighted (A, D), T1-weighted pre- (B, E), and post- (C, F) administration of intravenous gadolinium. Note the T2W hyperintense lesion extending from the thalamus to the midbrain [arrowhead in (A)], T1 hypointense non contrast enhancing lesion is mostly present within the thalamus. The lesion was markedly reduced in size at follow-up MRI, only present in the thalamus, and with the same MRI characteristics.
fvets-10-1146091-g0002.jpg
PMC10175592_01_fvets-10-1146091-g0002.jpg
F2
T2/T2 FLAIR hyperintense/T1 hypo- to isointense non-contrast enhancing lesion of the thalamus, that appeared moderately reduced in size and intensity, and no longer affected the midbrain, which was consistent with resolving myelinolysis. The lesions within the caudate nuclei, rostral cerebral peduncles, and claustrum were less evident (see Figures 1-3).
Transverse DWI and ADC map performed on day 4 of hospitalization (A-C) and at recheck 130 days later (D-F). Bilateral symmetric hyperintensity on DWI B0 images (A, D) and ADC map (C, F) is most consistent with T2 shine through. DWI B1000 showed mild hypointensity [arrow in (B)] not present at the follow up MRI (E), these findings were most consistent with non-restrictivity.
fvets-10-1146091-g0003.jpg
PMC10175592_01_fvets-10-1146091-g0003.jpg
F3
DWI showed hyperintense signal in the corresponding lesions on B0 images, and mildly hypointense signal on the B1000 (Figure 3). T2/T2 FLAIR hyperintense/T1 hypo- to isointense non-contrast enhancing lesion of the thalamus, that appeared moderately reduced in size and intensity, and no longer affected the midbrain, which was consistent with resolving myelinolysis. The lesions within the caudate nuclei, rostral cerebral peduncles, and claustrum were less evident (see Figures 1-3).