PMC7842592_01
(A) Radiation isodose treatment fields on pretreatment planning CT scan: red line 100% dose, purple line 70%, orange line 50%. (B) Pneumonitis developing in previously radiated lung fields 1 month after the start of everolimus treatment, 2 months after the completion of radiation treatment. (C) Progression of pneumonitis in previously radiated lung fields. (D) Interval resolution of diffuse infiltrates in the left lung at 12 weeks of follow-up.
OR-22-321-g001.jpg
PMC7842592_01_OR-22-321-g001.jpg
fig1
Initial workup for her respiratory failure with a computed tomography (CT) scan of the chest revealed a new, left-sided, patchy consolidation with confluent ground glass opacities, corresponding closely to the isodose margins of her prior radiation therapy fields (Figs. 1A, B, 2A, B). Respiratory failure and CT scan findings progressed within 2 weeks of her hospitalization to the point that she required high-flow oxygen in intensive care unit setting (Figs. 1C, 2C). At 12 weeks, follow-up CT scan revealed interval resolution of diffuse infiltrates in the left lung (Figs. 1D, 2D).
(A) Radiation isodose treatment fields on pretreatment planning CT scan: red line 100% dose, purple line 70%, orange line 50%. (B) Pneumonitis developing in previously radiated lung fields 1 month after the start of everolimus treatment, 2 months after the completion of radiation treatment. (C) Progression of pneumonitis in previously radiated lung fields. (D) Interval resolution of diffuse infiltrates in the left lung at 12 weeks of follow-up.
OR-22-321-g002.jpg
PMC7842592_01_OR-22-321-g002.jpg
fig2
Initial workup for her respiratory failure with a computed tomography (CT) scan of the chest revealed a new, left-sided, patchy consolidation with confluent ground glass opacities, corresponding closely to the isodose margins of her prior radiation therapy fields (Figs. 1A, B, 2A, B). Respiratory failure and CT scan findings progressed within 2 weeks of her hospitalization to the point that she required high-flow oxygen in intensive care unit setting (Figs. 1C, 2C). At 12 weeks, follow-up CT scan revealed interval resolution of diffuse infiltrates in the left lung (Figs. 1D, 2D).