PMC3693843_01
Fluorescein (left) and indocyanine green (right) angiography 122 seconds after dye injection. This angiography was performed 11 months prior to the first intravitreal dexamethasone implant injection.
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Funduscopy, fluorescein angiography (SPECTRALIS  OCT, Heidelberg Engineering, Heidelberg, Germany) (Figure 1) and spectral domain optical coherence tomography (OCT) (SPECTRALIS  OCT) were performed, and PCME with an underlying serous macular detachment was diagnosed.
Progression of pseudophakic cystoid macular edema and visual acuity following intravitreal injection with ranibizumab and dexamethasone implants.. Notes: All images were aligned during recording using eye tracking software. Day refers to days before or after the first dexamethasone implant injection.. Abbreviations: BCVA, best corrected visual acuity; CSMT, central subfield mean thickness; ETDRS, Early Treatment Diabetic Retinopathy Study; SD-OCT, spectral domain optical coherence tomography.
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The patient was referred to our department, where the central subfield mean thickness on OCT measured 640 mum, and BCVA was 73 letters on the ETDRS visual chart (Figure 2). The macular edema remained, with a central subfield mean thickness of 625 mum on OCT, but BCVA improved somewhat to 78 ETDRS letters (Figure 2). The edema subsided, and BCVA improved to 85 ETDRS letters and was maintained for an additional 189 days of follow-up, after the second injection (Figure 2).