PMC4925619_01
PET-CT showing pathological changes of the pleura before the immunosuppressive treatment.
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A PET-CT scan showed FDG uptake in pleura, mostly on the right side with bilateral pleural thickening and calcification (Fig. 1).
Immunoglobulin G immunostaining showing IgG positive plasma cells.
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The number of IgG4-positive plasma cells was on average 52 per high power field (HPF) with IgG4+/IgG plasma cell rate of 50% (Fig. 2, Fig. 3).
PET-CT showing complete remission of pleural activity after high dose prednisolone.
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Follow-up PET-CT showed first good response to the treatment (Fig. 4), and then progression of fibroinflammatory changes during prednisolone tapering.