PMC5836287_01
a Extensive dark erythema on the trunk and extremities. b, c Band-like infiltration of atypical lymphocytes with epidermotropism in the superficial dermis. d The administration of mogamulizumab improved the mSWAT score from 104 to 40.
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F1
On his initial visit, physical examination revealed extensive dark erythema (Fig. 1a). A biopsy specimen from the left abdomen revealed a band-like infiltration of atypical lymphocytes with epidermotropism in the superficial dermis (Fig. 1b, c). We treated the patient with mogamulizumab 1 mg/kg/week for 4 weeks, which improved the mSWAT score from 104 to 40 (Fig. 1d).
An infiltrated plaque recurred on the trunk and extremities (a) together with an elastic nodule on the tongue (b). c, d The infiltrated plaques and nodule on the tongue diminished 4 weeks after the administration of etoposide.
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F2
Because of grade 3 lymphopenia, we changed mogamulizumab to bexarotene (300 mg/m2/day) for 4 weeks and infiltrated plaque recurred on the trunk and extremities (Fig. 2a) together with an elastic nodule on the tongue (Fig. 2b). The infiltrated plaque and nodule on the tongue diminished 4 weeks after the administration of etoposide (Fig. 2c, d).