PMC3407972_01
The tumor exhibits a papillary pattern with vascular fronds from 9- to 2-o'clock position along the limbus extending onto the superior half of the cornea.
nihms-392441-f0001.jpg
PMC3407972_01_nihms-392441-f0001.jpg
F1
The tumor had a papillary pattern of growth with vascular fronds (Fig. 1).
A, The tumor is composed of keratinocytes with abundant clear cytoplasm and atypical nuclei. These cells occupied approximately twothirds of the tumor. B, Ultrastructural examination showing tumor cells with clear cytoplasm and residual intracytoplasmic glycogen granules (arrows). There are numerous intercellular junctions also present. A: hematoxylin-eosin, x100 and B: uranyl acetate lead citrate, x3600.
nihms-392441-f0002.jpg
PMC3407972_01_nihms-392441-f0002.jpg
F2
The keratinocytes had pleomorphic nuclei and abundant clear cytoplasm (Fig. 2A) that stained negative for glycogen, mucin, and lipid from the unembedded tissue. Examination of tissue submitted for electron microscopy from the embedded tissue showed tumor cells with clear cytoplasm and residual intracytoplasmic glycogen granules (Fig. 2B).