PMC9055382_01
Evaluation of the functionality of IL-12R by IFN-gamma production. The patient showed decreased production of IFN-gamma demonstrating defects in the function of the IL-12R.
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fig1
Functionality of the IL-12R was assessed measuring IFN-gamma production in response to recombinant human interleukin 12 (rhIL12) and phytohemagglutinin (PHA) (Fig. 1 ).
Evaluation of the functionality of IFN-gammaR by TNF-alpha production. The patient showed adequate production of TNF-alpha demonstrating correct function of the IFN-gammaR.
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Functionality of the IFN-gammaR was assessed measuring tumoral necrosis factor alpha (TNF-alpha) production in response to lipopolysaccharide and IFN-gamma at different concentrations (Fig. 2 ).
Brain abscesses and fourth ventricle tuberculoma. a) Sagittal T2 MRI showing multiple brain abscesses b) Transverse MRI enhanced with Gd showing a tuberculoma located in the fourth ventricle. c) intraoperative visualization of the tuberculoma.
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fig3
On July 1st, the patient was re-admitted to our hospital and a magnetic resonance imaging (MRI) of the head showed multiple brain abscesses (Fig. 3 ). On July 7th, the patient went through a non-successful resection of a fourth ventricle tuberculoma (Fig. 3).