PMC4006558_01
Clinical picture at time of first presentation and histological stains ((a) right breast, (b) cytokeratin 7 stain, (c) HE stain, and (d) left breast).
CRIDM2014-152836.001.jpg
PMC4006558_01_CRIDM2014-152836.001.jpg
fig1
A 72-year-old woman (para 1) was seen with erythematous and eczematous patches that developed simultaneously on both nipples and had been present for 2.5 years (Figures 1(a) and 1(d)). The histopathology showed epidermal cells with hyperchromatic and polymorphic nuclei, intraepithelial gland cells (Figure 1(b)), and a high expression of cytokeratin 7 (Figure 1(c)), so-called Paget's cells.