PMC3971538_01
Abdominal computed tomography scanning showing (a) thickening of the left bladder wall (arrows) with grade II left hydronephrosis (b).
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fig1
In March 2013, a follow-up abdominal CT scan displayed thickening of the left bladder wall with a grade II left hydronephrosis (Figure 1).
Metastatic lobular carcinoma. Bland-appearing tumor cells are arranged in strands with occasional single-signet ring-like cells, invading the stroma (hematoxylin & eosin, Nikon E1000, original magnification x100) (a) and metastatic cells stain positively for apocrine marker GCDFP-15 (Nikon E1000, original magnification x100) (b).
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fig2
Pathology showed an undifferentiated adenocarcinoma deeply infiltrating the bladder wall, featuring strands of loosely cohesive medium and small size with occasional signet ring-like cells, covered by normal urothelium (Figure 2(a)). Tumor cells were positive for CK 7, CK 19, GCDFP-15 (Figure 2(b)), ER, and PR, while they were negative for CK 20 and E-cadherin, thus suggesting bladder metastasis from lobular carcinoma of the breast.