PMC3579056_01
Photograph of the boy showing generalized hyperpigmentation
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F1
A 9-year-old male child presented with progressive darkening of skin over the whole body for last 3 years [Figure 1]. There was diffuse and uniform hyperpigmentation all over the body [Figures 1 and 2].
Photogragh of the boy during the follow-up visit showing hyperpigmentation and deteriorating neurological impairment
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PMC3579056_01_JNRP-4-70-g002.jpg
F2
There was diffuse and uniform hyperpigmentation all over the body [Figures 1 and 2].
MRI image showing bilaterally symmetric hyperintensities involving the thalami and adjacent putamen
JNRP-4-70-g003.jpg
PMC3579056_01_JNRP-4-70-g003.jpg
F3
Mild cerebral atrophic changes were also present [Figure 3].