PMC10244715_01
Case 1: In October 2023, a 60-year-old male presented to us with multiple blisters on erythematous skin (A). A treatment with topical and oral steroids was administered plus intravenous immunoglobulins and dapsone as add-on therapy. Three weeks later, he presented again with pruritus, erythema and multiple bullae (B), hence dupilumab was added to the treatment with dapsone and prednisolone. The skin continuously improved over the following weeks and oral steroids were tapered. At the 2-month follow-up, the patient did not show any new pruritic lesions or blistering (C).
fimmu-14-1179294-g001.jpg
PMC10244715_01_fimmu-14-1179294-g001.jpg
f1
At physical examination, multiple blisters ranging in size from millimeters to several centimeters and crusted lesions on erythematous skin were found on his whole body with accentuation on his thighs and upper body ( Figure 1A ). Three weeks later the patient presented with a new flare of pruritic skin erosions and blistering ( Figure 1B ). At the 2-month follow-up visit in January 2023, the patient reported major relief with no new pruritic lesions or blistering ( Figure 1C ).
PMC10244715_02
PMC10244715_03