PMC3482084_01
Macrophage infiltration in glomeruli and interstitium. Representative micrographs of CD68 staining are shown. Note numerous CD68-positive macrophages in glomeruli (A) and interstitium (B). Original magnification: x200.
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F1
In accordance with the Oxford-MEST score, his pathological findings were classified as M0, E1, S1, T0. In addition, numerous CD68-positive macrophages were observed in both glomeruli and interstitium (fig. 1).
The clinical course of a 41-year-old male patient with IgA nephropathy who received combination therapy including mizoribine. Longitudinal changes in 24-hour protein excretion (UPE), serum albumin (sAlb), serum creatinine (sCr), the number of urinary erythrocytes (/high-power field) (uRBC/HPF), and blood pressure (mm Hg) are shown. Note the apparent improvements in UPE and uRBC 12 months after beginning the combination therapy.
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F2
After diagnosis of IgAN, treatment with olmesartan 20 mg/day, dipyridamole 150 mg/day, and warfarin 1 mg/day was begun (fig. 2).