PMC6062775_01
Renal cortex containing glomeruli with ischemic-type wrinkling of capillary walls (blue arrow). There is a background of diffuse interstitial fibrosis and tubular atrophy (red arrow). Arteries show prominent thickening due to concentric smooth muscle hyperplasia (yellow arrow;. Jones methenamine silver stain, original magnification 10x).
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The majority of the remaining glomeruli show prominent ischemic-type wrinkling of capillary walls (Figure 1).
Artery with necrotizing vasculitis, with prominent transmural necrosis and inflammatory infiltrate (Jones methenamine silver stain, original magnification 20x).
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Necrotizing vasculitis of the artery is seen, with prominent transmural necrosis and inflammatory infiltrate with prominent thickening of surrounding arterioles due to concentric hyperplasia (Figure 2).
Crescent formation (yellow arrow; Jones methenamine silver stain, original magnification 20x).
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Ten percent of glomeruli per section show crescents (Figures 3).