PMC5121443_01
Pelvic computed tomography showing a 9 cm heterogenous mass in right testicle (a). Abdominal CT scan showed multiple hepatic masses (b) and one large heterogenous retroperitoneal mass (c) measuring up to 13 cm in greatest dimension, consistent with metastatic disease.
CRIPA2016-7318672.001.jpg
PMC5121443_01_CRIPA2016-7318672.001.jpg
fig1
Pelvic computed tomography (CT) showed a 9 cm heterogeneous mass in the right testis (Figure 1(a)). CT scan showed multiple hepatic masses and one large heterogenous retroperitoneal mass measuring up to 13 cm in greatest dimension, consistent with metastatic disease (Figures 1(b) and 1(c)). Chest CT was remarkable for multiple pulmonary nodules measuring up to 2.1 cm in greatest dimension.
(a) Encapsulated solid mass with interspersed cystic areas. Yolk sac tumor component (b), embryonal carcinoma component (c), and teratoma component (d) were identified. (e) Nephroblastoma component shows typical blastema and epithelial components. (f) Nephroblastoma component has strong WT-1 expression.
CRIPA2016-7318672.002.jpg
PMC5121443_01_CRIPA2016-7318672.002.jpg
fig2
The cut surface of the tumor was soft and tan-brown to yellow in color (Figure 2(a)). Microscopically, the testicular tumor was composed of immature teratoma with nephroblastoma (40%), mature teratoma, embryonal carcinoma and yolk sac tumor (Figures 2(b)-2(d)). The nephroblastoma component consisted of undifferentiated blastema, fibroblast-like stroma and epithelial elements (Figure 2(e)). Immunohistochemical stain for WT-1 was strongly positive in the nephroblastoma component only (Figure 2(f)).