PMC9784141_01
Mammography of the left breast in 2016 shows a group of new micro- and macrocalcifications (irregular pleiomorphic, tubular and linear) of 2 cm at 9h (a: medial part on craniocaudal incidence, b: caudal part on medial-oblique incidence). No associated architectural distortion or mass.
jbsr-106-1-2988-g1.jpg
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F1
However, the mammography in the left breast showed new calcifications in comparison to the screening mammography of 2013 (see Figure 1).
APD amyloid deposition. a. Hematoxylin and eosine staining, amyloid is bright pink. b. Congo red, amyloid is red. c. Congo red under polarized light, amyloid is apple-green.
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F2
Figure 2). Further staining for kappa and lambda (AL type) was negative, whereas Amyloid A and transthyretin were positive suggesting the diagnosis of AA type amyloidosis.
Mammography of the right breast in 2018 shows new micro- and macrocalcifications (fine regular and punctiform) of 2 cm at 11h (a: lateral part on craniocaudal incidence, b: cranial part on medial-oblique incidence). No architectural distortion or mass.
jbsr-106-1-2988-g3.jpg
PMC9784141_01_jbsr-106-1-2988-g3.jpg
F3
Nevertheless, the screening mammography of 2018 showed new calcifications in the right breast and amyloidosis (Amyloid A) was confirmed on vacuum biopsy again (see Figure 3).