PMC6818339_01
Abdominal thin slices CT scan in axial plan : non enhanced (a), arterial (b) and portal acquisition (c). Coronal oblique thin slice CT scan (d): Lobulated density mass, in the gallbladder, with intense arterial enhancement after contrast injection, and retracting gallbladder wall (black arrows). It was associated with gallstones (white arrow).
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Intraluminal gallstones were found (Fig. 1).
The polyp is consisted of clear cells sheets ( ), nests and cords separated by a delicate capillary vascular network (HEx50).
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Microscopically, the polyp consisted of clear cell sheets, nests, and cords separated with a delicate capillary vascular network (Fig. 2).
Details of tumor cells with an abundant clear cytoplasm ( ) and a round uniform nucleus (HEx200).
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The nucleus was round and uniform (Fig. 3).
Negative staining for cytokeratin (IHCx200).
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The diagnosis of metastatic RCC was confirmed by immunohistochemical stains, which showed strong positivity for vimentin and PAX8, patchy positivity for CD10 and negativity of pancytokeratin (Fig. 4, Fig. 5).