PMC3295565_01
CT findings of angiosarcoma of the diaphragm (tumors were located under the chest, a huge volume, heterogeneous enhancement, No mediastinal lymph nodes).
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fig1
High-density shadow was found in lower left chest after chest film examination, and the further CT revealed a mass opacities with inhomogeneous density and slight enhancement in lower left thoracic cavity, and no mediastinal lymph nodes, as well as a small amount of effusion (see Figure 1).
Histopathological microscopic structure of diaphragm angiosarcoma (tumor cell atypia, abnormal vessel-like cavities structure).
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fig2
The histology results were most compatible with moderately differentiated angiosarcoma, as shown in Figure 2, in low magnification (L) and high magnification (R).
Epithelioid cells strongly positive with CD34 (x200).
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fig3
The diagnosis result was supported by the immunophenotypes CD34 (++) (see Figure 3), CD31 (+), Vimentin (+), epithelial membrane antigen [EMA(-)] phosphoenolpyruvate carboxykinase [PCK(-)], factor VIII related antigen [FVIII (-)], as well.