PMC5360069_01
Peripheral blood smear demonstrating extensive presence of schistocytes
40425_2017_224_Fig1_HTML.jpg
PMC5360069_01_40425_2017_224_Fig1_HTML.jpg
Fig1
Examination of the peripheral blood smear (Fig. 1) showed marked anisocytosis, severe decrease in platelets and the presence of abundant schistocytes.
Vertical axis: values of serum creatinine, lactate dehydrogenase (LDH), hemoglobin, and platelet count during hospitalization in relation to treatment with plasmapheresis, systemic corticosteroids, intravenous immunoglobulin (IVIG) and rituximab therapy. Horizontal axis: time in days
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PMC5360069_01_40425_2017_224_Fig2_HTML.jpg
Fig2
During hospitalization, the patient received the following interventions: 5 courses of plasmapheresis with plasma exchange (9/16, 9/18, 9/19, 9/21, and 9/23), transfusion of 4 units of packed red blood cells, one unit of platelets, IV gammaglobulin 2 g over two days (9/17 and 9/18), and rituximab 375 mg/m2 (9/24/15) (Fig. 2). 