PMC5789125_01
A 45-year-old woman presenting with multiple anterior mediastinal masses. (a, b) On contrast-enhanced computed tomography (CT), the masses demonstrated homogeneous enhancement with partial calcification (arrowheads).
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They measured 9 x 6 x 4 cm and 2.5 x 1.5 x 2.0 cm (Fig. 1a, b).
Magnetic resonance imaging (MRI) findings. (a) A T1-weighted image (T1WI) demonstrated a well-defined isointense mass. (b) A T2-weighted image (T2WI) demonstrated a mixture of isointense and hyperintense areas.
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On magnetic resonance imaging (MRI), a T1-weighted image (T1WI) demonstrated a well-defined isointense mass (Fig. 2a, b). A T2-weighted image (T2WI) demonstrated a mixture of isointense and hyperintense areas (Fig. 2c, d).
FDG-PET images showed uptake in the 2 masses. The maximum standardized uptake value (SUV) of 2 lesions were (a) 26.0 and (b) 13.6.
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Positron-emission tomography (PET) with 2-[18F]fluoro-2-deoxy-d-glucose (FDG) images revealed uptake in the 2 masses (Fig. 3a, b).
(a) Histologically, the biopsy specimen showed a foreign body granuloma featuring deposition of many small crystals and foreign-body giant cells (Hematoxylin and eosin staining, original magnification 200x.). (b) Under polarized light, the deposited materials demonstrated string-like crystals and appeared to be refractive.
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Under polarized light, the deposited materials appeared as string-like crystals and appeared to be refractive (Fig. 4).