PMC3166762_01
Sarcomatoid urothelial carcinoma. Tumor comprised of sheets of epithelioid and plump spindle cells which are highly pleomorphic with nuclear hyperchromasia. There is prominent stromal inflammatory response to the invading tumor with destruction of the bladder wall. (Hematoxylin & eosin, original magnification x100).
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fig1
Microscopic examination of the prior bladder tumor demonstrated mixture of highly atypical malignant epithelioid and spindle cells (Figure 1), which demonstrated diffuse immunoexpression of pancytokeratin and cytokeratin 20.
Prostatic adenocarcinoma: The large nodules of tumor cells, invading the stroma, are arranged mainly as sheets of cells and fused acini. Prominent perineural invasion is identified. (Hematoxylin & eosin, original magnification x100).
PRI2011-173541.002.jpg
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fig2
In 2006, he had radical retropubic prostatectomy and radiotherapy for a prostate adenocarcinoma, Gleason's score 4 + 4 = 8 (Figure 2).