PMC3425344_01
Skin lesions presented as a large area of erythematous infiltrated plaques and nodules with scales, sporadic ulcers, and scabs on the upper right side of the patient's face and almost the entire forehead.
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Dermatological examination revealed a large area of erythematous infiltrated plaques and nodules with scales, sporadic ulcers, and scars on the upper right side of the patient's face and almost her whole forehead (Figure 1).
Histopathology with hematoxylin and eosin staining showed infective granuloma and multinucleated giant cells: (A) infective granuloma in dermis (original magnification, x40); (B) epithelioid cells and multinucleated giant cells (original magnification, x200).
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A skin biopsy, taken from a lesion on the patient's forehead, stained with hematoxylin and eosin showed hyperplastic epidermis and epithelioid cell granulomas that were composed of tissue cells and multinucleated giant cells; infiltration with lymphocytes and eosinophils was further observed (Figure 2).