PMC8361521_01
Hands and foot of a first case 10 days after treatment with topical corticosteroids and acitretin (left) and hands and foot of a first case 2 years after apremilast therapy (right).
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Patient 1 was a 51-year-old woman who presented with numerous small pustules on her palms and feet on and erythematous background (Figure 1).
PMC8361521_02
Hands and feet of a second patient 1.5 year after apremilast therapy (left) and hands of a third case before apremilast therapy (upper right) and 3 months after apremilast therapy (lower right).
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Patient 3 was a 58-year-old man with a history of plaque type psoriasis and psoriatic arthritis (Figure 2 right).
PMC8361521_03
Hands and feet of a second patient 1.5 year after apremilast therapy (left) and hands of a third case before apremilast therapy (upper right) and 3 months after apremilast therapy (lower right).
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Patient 3 was a 58-year-old man with a history of plaque type psoriasis and psoriatic arthritis (Figure 2 right).