PMC5871378_01
Irregular and poorly delimited brownish macules and spots on the
back
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f1
Dermatological examination revealed nodules of 0.5-1 cm on the upper limbs and poorly delimited irregular brownish spots on the trunk, back (Figures 1 and 2), and lower limbs, in addition to an ulcer on the left knee with an infiltrated, raised and keratotic border with granular erythematous floor, of approximately 7cm in size (Figure 3).
Brown colored erythematous nodules of 0.5-1.0 cm in size located on
the proximal part of the upper limbs
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f2
Dermatological examination revealed nodules of 0.5-1 cm on the upper limbs and poorly delimited irregular brownish spots on the trunk, back (Figures 1 and 2), and lower limbs, in addition to an ulcer on the left knee with an infiltrated, raised and keratotic border with granular erythematous floor, of approximately 7cm in size (Figure 3).
Ulcerated plaque of approximately 7cm in size, with granular floor
and raised and keratotic border on the left knee
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f3
Dermatological examination revealed nodules of 0.5-1 cm on the upper limbs and poorly delimited irregular brownish spots on the trunk, back (Figures 1 and 2), and lower limbs, in addition to an ulcer on the left knee with an infiltrated, raised and keratotic border with granular erythematous floor, of approximately 7cm in size (Figure 3).
Diffuse interstitial chronic dermatitis, with lymphohistiocytic
infiltrate (Hematoxylin & eosin, X10)
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f4
Ultrasound biopsy showed diffuse interstitial chronic dermatitis with lymphohistiocytic infiltrate, which revealed, in the cytoplasm of some histiocytes, rounded structures with morphology compatible with amastigotes of Leishmania, confirming the diagnosis of cutaneous leishmaniasis (Figures 4 and 5).
Presence of structures compatible with Leishmania in
the cytoplasm of histiocytes (PAS, X40)
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f5
Ultrasound biopsy showed diffuse interstitial chronic dermatitis with lymphohistiocytic infiltrate, which revealed, in the cytoplasm of some histiocytes, rounded structures with morphology compatible with amastigotes of Leishmania, confirming the diagnosis of cutaneous leishmaniasis (Figures 4 and 5).