PMC5943108_01
CT scan of lung windows and mediastinal windows in case 1 after Icotinib treatment and after Crizotinib treatment. CT = computed tomography.
medi-97-e9021-g001.jpg
PMC5943108_01_medi-97-e9021-g001.jpg
F1
Imaging studies showed a mass in the right upper lung with mediastinal lymph nodes enlargement (Fig. 1A and F). A CT scan showed a progressive lung mass with pleural effusion (Fig. 1C and H). Moreover, CT scan performed at 2 months after crizotinib treatment showed that the mass and pleural effusion reduced significantly (Fig. 1D and I). The CT scan showed enlargement of mass and the increasing of pleural effusion (Fig. 1E and K).
PMC5943108_02
CT scan of lung windows and mediastinal windows in case 2 after Icotinib treatment and after Crizotinib treatment. CT = computed tomography.
medi-97-e9021-g002.jpg
PMC5943108_02_medi-97-e9021-g002.jpg
F2
A 50-year-old never-smoker woman, experiencing cough and dyspnea for 2 years, underwent a CT scan, which showed a mass in the left lung (Fig. 2A and F). After a 23-month (progression free survival) PFS, disease progressed with enlarged mass in the left lung accompanying with increased pleural and pericardial effusion (Fig. 2C and H). CT scan performed 1 month later showed a significant decrease in mass and a marked reduce in pleural and pericardial effusion (Fig. 2D and I). The CT scan at 6 months after crizotinib showed a persist decrease of mass (Fig. 2E and K).