PMC5959028_01
CT for head segment
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F1
Given the unfavorable evolution, we repeated the CT for head segment, which showed multiple supratentorial lesional processes predominantly in the white matter and calf body and a few isolated thalamic lesions that raised the suspicion of brain microabscesses in a septic context (Fig. 1).
Fundus of the right eye, showing a massive retinal hemorrhage 6 days after admission
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F2
The examination of the posterior pole revealed marked changes of the retina and optic disc with massive hemorrhages that practically covered a large part of the posterior pole for the LE and for the RE extensive retinal hemorrhage, marked papillary edema, both eyes with vitreous condensation (Fig. 2,3).
Extended cutaneous hemorrhage syndrome
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F4
The patient was transferred to the hematology department having an extended mucosal cutaneous hemorrhage syndrome (Fig. 4), hepatic cytolysis syndrome and started the specific treatment for LAM3 with Vesanoid 45 mg/ m2 - 80 mg/ day.