PMC5362842_01
(a) Dorsoventral thoracic radiograph of a 15-year-old cat demonstrating a large cranial mediastinal mass. The mass extends in the left hemithorax from the level of the thoracic inlet (cranial arrow) to the level of the left diaphragmatic outline (caudal arrow). The cardiac silhouette (arrowheads) is displaced to the right. There is evidence of mild displacement of the trachea to the right as a result of the mass effect created by the cranial mediastinal mass. (b) Left lateral thoracic radiograph demonstrating a large cranial mediastinal mass extending from the level of the thoracic inlet (cranial arrow) to the diaphragmatic outline (caudal arrow)
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(a) Transverse image after contrast computed tomography of the thorax of a 15-year-old cat, at the level of the heart, demonstrating a large cranial mediastinal mass. (b) Three dimensional (3D) reconstruction of the thymoma prior to chemotherapy. The mass is outlined and the volume estimated using 3D reconstruction. The volume of the mass was 180.7 cm3
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Pre- and postcontrast (iohexol 600 mg/kg IV [Omnipaque; GE Healthcare]) images were examined in soft tissue and lung windows, and three-dimensional (3D) reconstruction was performed (Figure 2a,b).
(a) Dorsoventral thoracic radiograph of a 15-year-old cat with a mediastinal mass (arrows) obtained 3 weeks after commencement of chemotherapy. There is a marked reduction in the size of the mass compared with Figure 1. The mass causes border effacement of the cardiac silhouette. (b) Right lateral thoracic radiograph. The mass has reduced in size considerably and is superimposed over the cardiac silhouette (arrows)
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Two weeks after vincristine administration, repeat thoracic radiographs showed a reduction in the size of the mass (Figure 3a,b).
(a) Transverse image after contrast computed tomography of the thorax of a 15-year-old cat, at the level of the heart, demonstrating a cranial mediastinal mass 5 weeks after the start of chemotherapy. (b) Three-dimensional (3D) reconstruction of the thymoma following chemotherapy. The mass is outlined and the volume estimated using 3D reconstruction. The volume of the mass was 9.4 cm3, representing a 95% reduction in volume of the mass when compared with the previous CT examination
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Thoracic CT was repeated 2 weeks after doxorubicin administration (5 weeks after initiation of chemotherapy) for presurgical planning (Figure 4a,b).