PMC4734679_01
(A) T2W axial MRI showing patchy hyperintense lesions in the pons and cerebellar peduncles. (B) T1W axial MRI after intravenous Gadolinium contrast administration showing the typical punctate contrast enhancement of CLIPPERS in the cerebellum.
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A second MRI with gadolinium contrast was requested then, which showed the same patchy lesions in the brainstem (Figure 1A) but with no gadolinium enhancement. On May 2000, a control MRI between relapses showed a patchy and curvilinear gadolinium enhancement on T1-weighted images, peppering the cerebellum (Figure 1B).