PMC9733999_01
Placental pathology in SARS-CoV-2 infection; haematoxylin and eosin staining. Heavy intervillous acute and chronic inflammatory infiltrates narrow a collapsing intervillous space.
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fig1
Heavy intervillous acute and chronic inflammatory infiltrates could be observed (Figure 1), admixed with variable amounts of increased perivillous fibrinoid deposition, highlighted by special phosphotungstic acid haematoxylin (PTAH) stain (Figure 2). Extreme narrowing of already collapsing intervillous space by inflammatory infiltrates was seen (Figure 1).
Increased perivillous fibrinoid deposition, phosphotungstic acid haematoxylin (PTAH) stain.
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fig2
Heavy intervillous acute and chronic inflammatory infiltrates could be observed (Figure 1), admixed with variable amounts of increased perivillous fibrinoid deposition, highlighted by special phosphotungstic acid haematoxylin (PTAH) stain (Figure 2).
Inflammatory intervillous infiltrate; CD68 positive hystiocytes.
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fig3
Inflammatory intervillous infiltrate; CD15 positive neutrophils.
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fig4
Positive immunohistochemistry staining of syncytiotrophoblasts with spike protein antibody.
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fig5
Positive immunohistochemistry staining of syncytiotrophoblasts with spike protein antibody showed a granular binding pattern in syncytiotrophoblasts (Figure 5).