PMC3804804_01
Contrast enhanced cardiac magnetic resonance imaging at the time of initial diagnosis (left) confirmed the finding of a mass measuring 5.5x3.9x4.8 cm in the left ventricle which involved the entire thickness of the myocardium from the endocardial surface to the pericardium. The image in the right panel demonstrates development of central necrosis within the tumor, consistent with response to sunitinib.
rt-2013-3-e29-g001.jpg
PMC3804804_01_rt-2013-3-e29-g001.jpg
fig001
Since initiation of systemic therapy, serial MRIs have shown remarkable stability in the size of the ventricular mass, with gradual development of central necrosis (Figure 1).
PMC3804804_02
A) Initial echocardiogram showing a 5.3x5.9 cm mass (surrounded by the 4 arrows) arising from the anterior ventricular septum with extension into the right ventricle (RV). B) demonstrates stability in the size of the mass after targeted therapy with sunitinib for 3 years.
rt-2013-3-e29-g002.jpg
PMC3804804_02_rt-2013-3-e29-g002.jpg
fig002
This led to an echocardiogram which showed a 5.3x5.9 cm mass arising from the anterior ventricular septum with extension into the right ventricle (Figure 2A). Currently, he is asymptomatic, with stable disease (Figure 2B) and no signs of hemodynamic compromise on a stable dose of sunitinib.