PMC10436340_01
Post-contrast T1-weighted sagittal (A) and transverse (B) images aligned with the C2 axis to show left and dorsal displacement of the dens (red arrow) in relation to C1 (green arrow shows ventral margin), causing marked cord compression (blue arrow).
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F1
There was marked compression of the spinal cord at this site with heterogeneous increased T2W intensity of the cord at C1-C2 (Figure 1).
Histopathological findings, antebrachial skin. (A) Affected dog. (B) Normal dog. Abnormal dermal collagen fibers are irregularly and often loosely distributed, with increased variation in fiber size and width (arrows), and irregular and sometimes large spaces between collagen fibers (asterisks). In some regions there are increased numbers of plump fibroblasts (arrowheads). Hematoxylin and eosin, bar = 50 mum.
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F2
On routine light microscopic examination of H&E-stained sections, the dermal collagen fibers from this patient were strikingly different from the controls, being irregularly and often loosely oriented, with increased variation in size and shape and increased numbers of dermal fibroblasts (Figure 2).