PMC4646594_01
Fundus findings at the initial visit.. Notes: Fundus images show serous retinal detachment in the right (A) and left eyes (B). Mid-phase FA (4 minutes) show multiple punctuate hyperfluorescent lesions in the right (C) and left eyes (D). Late phase FA (25 minutes) shows multilobular pooling of the dye in the right (E) and left eyes (F). Early-phase ICGA (15 seconds) show a filling delay in the choroid of the right (G) and left eyes (H). Mid-phase ICGA (7 minutes) shows focal areas of hyperfluorescence in the right (I) and left eyes (J).. Abbreviations: FA, fluorescein angiograms; ICGA, indocyanine green angiograms.
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Ophthalmoscopy showed SRD in the posterior poles of both eyes (Figure 1A and B). Bilateral FA images showed multiple foci of fluorescein leakage during the mid-phase (4 minutes after injection) (Figure 1C and D) and pooling of the dye in the subretinal spaces during the late phase (25 minutes after injection) (Figure 1E and F). ICGA showed delayed filling of the choroidal circulation in the early-phase images (Figure 1G and H), which subsequently became mottled with hyperfluorescent lesions during the mid-phase (7 minutes) (Figure 1I and J), suggesting choroidal hyperpermeability.
Horizontal scan images (6.0 mm) from the spectral-domain OCT of the right (A and C) and left eyes (B and D).. Notes: At the initial visit, OCT through the fovea shows a large SRD that included areas of the macula and increased choroidal thickness (which can be observed because of the invisible choroid-scleral interface) in both eyes (A and B). At 40 days after the initial visit, OCT shows not only the disappearance of the SRD, but also marked improvement of the choroidal thickening (which can be observed because of the visible choroid-scleral interface depicted by the arrowheads) (C and D).. Abbreviations: OCT, optical coherence tomography; SRD, serous retinal detachment.
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At 40 days after the initial examination, her CVA were 1.2 in both eyes, and OCT revealed both the disappearance of the SRD and marked improvement of the choroidal thickening (which could be observed because of the visible choroid-scleral interface) (Figure 2C and D).