PMC6180858_01
Patient 1. Nasal mass biopsy. Thick collagen bundles with perivascular fibrosis in an "onion-skin" type whorling pattern. Eosinophil-rich inflammatory infiltrate is also present (haematoxylin and eosin).
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A biopsy revealed rich inflammatory infiltrate surrounding the blood vessels with a prominent onion-skin pattern, consistent with EAF extension into bony and skeletal muscle tissue (Figure 1).
MRI of patient 1. (a) Coronal T
2 (b) sagittal T
1 and (c) coronal T
1 weighted images showing a central soft tissue mass bilaterally infiltrating the nasolabial folds, inferior and middle turbinates, and nasal septum, with soft tissue thickening extending to the nasal bridge. There is mild narrowing of both nasal vestibules.
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MRI showed a lobulated diffuse soft tissue mass of the nasolabial folds bilaterally, extending posteriorly to involve the anterior half of the inferior and middle turbinates as well as the anteroinferior nasal septum, mildly narrowing both nasal vestibules (Figure 2).
PMC6180858_02
Patient 2. Nasal biopsy demonstrating prominent perivascular fibrosis with numerous eosinophils (haematoxylin and eosin).
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MRI showed the anterior septal mass extending into the pre-maxillary space with partial erosion of the hard palate (Figure 3).
Patient 2. Coronal CT scan showing a nasal mass measuring 2.6 x 3.1 x 2.9 cm predominantly to the left of the nasal septum and extending across the midline to the right. The lesion also extends into the premaxillary space. The erosion through the left hard palate is significant.
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