PMC2862318_01
Radiological and histopathological features are shown here. Figure 1(a): preoperative CT-scan, Figure 1(b): gross histopathology and Figure 1(c): microscopy features. See text for details.
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Clinical examination revealed tender hepatomegaly, and a contrasted computed tomography (CT) scan of the thorax, abdomen, and pelvis showed a large solitary heterogeneous mass in segment V1 of the liver with evidence of intratumoural bleeding (Figure 1(a)). The tumour measured 15 x 11 x 20 cm and cut section revealed massive necrosis and haemorrhage consistent with the preoperative CT scan (Figure 1(b)). Histological examination of the tumour showed a malignant biphasic neoplasm consisting of a moderately differentiated adenocarcinoma intermingled with a malignant mesenchymal component (Figure 1(c)).
Postoperative CT-scan showing early disease recurrence (indicated with an arrow) within the liver (Figure 2(a)). Partial response after completion of chemotherapy is shown in Figure 2(b).
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A postoperative contrasted CT scan at 5 weeks confirmed rapid onset disease recurrence with multiple peritoneal deposits and multifocal liver metastasis (Figure 2(a)). Patient received a total of six cycles of chemotherapy and a restaging CT scan at the end of 6 cycles confirmed partial response (Figure 2(b)).