PMC10075267_01
Early asymmetrical orbits involvement and constant depression in primary position of the right ocular globe (A and B).
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In addition, the patient presented a severe reduction in elevation, persistent depression in the primary position of the right ocular globe (Figure 1) and constant diplopia, as scored according to the Gorman score.
Coronal (A) and axial (B) CT slices shows massive enlargement of inferior rectus in right orbit.
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Remarkably, the morphology of the other extraocular muscles in both orbits was normal (Figure 2A and B).
Photos at 100x (A) and 200x (B) magnification of right inferior rectus biopsy show diffuse fibrosis, fibroblast proliferation and adipose tissue infiltration inside intermyofibrillar space.
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In that context, a biopsy of the right inferior rectus muscle revealed massive fibrosis with adipose tissue infiltration of this extraocular muscle (Figure 3A and B).