PMC3420721_01
(a) H&E stained frozen section of the muscle biopsy showing normal architecture (x100). (b) Oil Red-O method, which is used for highlighting neutral triglycerides and lipids in frozen sections, showed several orange-red-stained droplets of lipids, a finding consistent with the clinically suspected diagnosis of lipid storage disease (x1000).
CRIM.RHEUMATOLOGY2012-283259.001.jpg
PMC3420721_01_CRIM.RHEUMATOLOGY2012-283259.001.jpg
fig1
In muscle biopsy, the overall morphology and the architecture with hematoxylin and eosin (H&E) stain were within normal histological appearance (Figure 1(b)). However, Oil Red-O staining disclosed several orange-red-stained droplets of lipids in the sarcoplasms of many muscle fibers, which was consistent with lipid storage myopathy (Figure 1(a)).