PMC8194346_01
Patient exhibited pseudoprogression of pulmonary lesions after 2 months of treatment with nivolumab plus CIK cell transfer and achieved a partial remission after 4 months.
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After 6 months of therapy, a CT showed that the lesions in the lungs had begun to decrease ( Figure 1 ).
MRI during treatment with nivolumab and CIK cells. MRI revealed two enhancing metastatic lesions within the brain parenchyma 6 months after the initiation of treatment. The brain lesions disappeared after 6 months of continued treatment.
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After an additional 5 months (May 2019), symptoms disappeared, and another enhanced MRI found the brain lesions had disappeared ( Figure 2 ).
Timeline of the patient treatment.
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The timeline of the patient's disease development, treatment and outcome is shown in  Figure 3 .