PMC2816851_01
High-resolution computed tomography of the chest depicts a well-circumscribed, multiseptate, air-filled cystic lesion in the upper lobe of the right lung.
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F1
High-resolution computed tomography (HRCT) of the chest depicted a well-circumscribed, multiseptate, air-filled cystic lesion in the upper lobe of the right lung, mimicking the feature of type I congenital cystic adenomatoid malformation (Fig. 1).
1:1 scaned photograph shows a large intrapulmonary cystic tumor (Ly), causing emphysematous change (Em) in surrounding pulmonary parenchyma (H&E, x1).
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F2
Histopathological examination of the upper lobe revealed a relatively circumscribed intrapulmonary cystic lesion composed of multiple cysts or cavities (Fig. 2).
The cystic walls (in the right top) of the tumor are supported by loose fibrous tissue and adjoin to the emphysematous lung tissue (in the left) (H&E, x20).
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F3
Their walls were supported by loose fibrous stroma with mild lymphocytic infiltrate (Fig. 3).
Immunohistochemical staining for factor VIII-related antigen shows weak positive reactions in the lining cells of the cystic walls (Streptavidin-biotin, x100).
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F4
In the immunohistochemical staining the lining cells of the cystic walls were not reactive for epithelial membrane antigen and cytokeratin, but weakly positive for factor VIII-related antigen (Fig. 4).