PMC10161292_01
Physical examination findings: (A) telangiectasias on mucosal aspect of lower lip; (B) sclerotic hyperpigmented plaque on the abdomen; (C) edematous swelling of hands; and (D) multiple sclerotic plaques on the bilateral lower extremities.
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PMC10161292_01_10.1177_23247096231171251-fig1.jpg
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Physical examination was significant for multiple telangiectasias on the mucosal aspect of her lower lip, tightening of the skin on the bilateral upper extremities distal to the elbow (most significant in hands and fingers) and hyperpigmented thickened plaques on lower left abdomen and both legs (Figure 1).
Changes of obliterative portal venopathy and nodular regenerative hyperplasia. (A) Portal area with small portal veins displaced out of the portal area (H&E, 400x). (B) Sinusoidal dilation (H&E, 200x). (C) Delicate perisinusoidal fibrosis (Masson trichrome, 400x). (D) Vague nodularity with zone of narrowed liver cell plates (arrows; Reticulin, 200x).. Abbreviation: H&E, hematoxylin and eosin.
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PMC10161292_01_10.1177_23247096231171251-fig2.jpg
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Pathology identified obliterative portal venopathy and NRH with no inflammation and minimal perisinusoidal fibrosis (Figure 2).