PMC10214094_01
Blood pressure values during bevacizumab treatment.. SBP: systolic blood pressure; DBP: diastolic blood pressure.
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The maintenance treatment was well tolerated, with no side effects related to bevacizumab, notably hypertension (Figure 1), proteinuria or thromboembolic events.
Initial and follow-up MRI.. Day 1 brain MRI (top row) showed, from left to right, high signal intensity
of the left occipital cortex and subcortical white matter (orange arrow) on
fluid-attenuated inversion recovery (FLAIR), with no lesion on
diffusion-weighted imaging (DWI) and increased apparent diffusion
coefficient (ADC) values (orange arrowhead), consistent with vasogenic
edema. The follow-up study (bottom row) performed on day 4 demonstrated
partial resolution with minor residual subcortical FLAIR hyperintensities in
the left occipital lobe (white arrow) and normalized ADC values (white
arrowhead).
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Axial fluid-attenuated inversion recovery (FLAIR) images showed high signal intensities involving the cortex and the subcortical white matter in the posterior parietal and occipital regions bilaterally without restricted diffusion, consistent with vasogenic edema and highly suggestive of PRES (Figure 2).