PMC7518776_01
The cornea under Nd:YAG laser treatment. (A) The cornea immediately after the laser shot. Opaqueness caused by corneal edema (yellow arrow), and laser spots were observed. (B) The cornea 1 month after the laser shot. Opaqueness still maintained in the pupil area (yellow arrow). (C) The retro-illumination of the cornea 3 months after the operation. As the opaqueness disappeared, the trace of the laser spots became more distinctive (yellow arrows). (D) Nd:YAG laser treatment at 3 months after the first trial.
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A slit-lamp examination revealed the laser spots in the stromal and endothelial cell layers and swollen stroma in the cornea (Figure 1A). Thus, 0.1% betamethasone sodium phosphate eye drops had been administered to decrease the swelling of the cornea (Figure 1B). As the corneal opaqueness decreased, the trace of the laser shot became visible with the slit-lamp examination (Figure 1C). No complication was observed during and after the procedure, and the visual acuity improved up to 20/20 on the following day (Figure 1D).
Endothelial cell densities. Endothelial cell densities at (A) 3 months, (B) 1 year, (C) 2 years, (D) 2.5 years, and (E) 3 years after the first laser trial. Endothelial cell densities in the fellow eye at 3 years (F).
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Endothelial cell densities and corneal thickness were 2415 cells/mm and 543 microm at the central part of the cornea, respectively (Figure 2A). At 1 year after the first laser trial, endothelial cell densities and corneal thickness were 2245 cells/mm and 552 microm, respectively (Figure 2B). However, these values changed into 908 cells/mm and 575 microm (Figure 2C), 837 cells/mm and 586 microm (Figure 2D), and 698 cells/mm and 592 microm (Figure 2E) at 2, 2.5, and 3 years, respectively. On the other hand, the endothelial cell density and corneal thickness were 2404 cells/mm and 581 microm in the right eye at 3 years (Figure 2F).