PMC3354389_01
Photograph of the left thigh: an ulcerated and infected nodule.
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F1
We report a case of an 80-year-old man who presented with an ulcerated and infected nodule in the left thigh (Fig. 1) of five months duration.
a: Tumor shows a mixture of atypical enlarged basaloid, epithelioid cells (HE x 100). 2: b: Sebaceous differentiation (HE x 200).
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F2
Histologic examination revealed an intradermic proliferation of atypical enlarged basaloid and epithelioid cells, intermixed with focal mature sebocytes (Fig. 2a, 2b).
Cytological atypia and mitotic activity were remarkable (HE x 400).
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F3
Cytological atypia and mitotic activity were remarkable with focal necrosis (Fig. 3).
Immunoreactive positivity for CK7 (IHC x 400).
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F4
Tumor cells were immunoreactive for cytokeratin 7 (Fig. 4).