PMC6073164_01
A: Photograph of the lesion of the back prior to surgical intervention. Scar in the midline indicates possible biopsy of previous approach. The tumor is roughly marked by the extension of the circular nevus covering the entire lower back.. B: Photograph of the back following debulking procedure and completion of wound healing.
IPRS-7-04-g-001.jpg
PMC6073164_01_IPRS-7-04-g-001.jpg
F1
On the back there was a tumorous protrusion of the intact skin with a maximum above the spine, which extended from the lower thoracic region close to the edge of the pelvis (Figure 1 A (Fig. 1)). Secondary wound healing took 21 days and led to a stable healed wound (Figure 1 B (Fig. 1)).
A: Photograph of the resection specimen with hyperpigmented skin. B: Photograph of the resection specimen with the upturned resection surface. Note the stripe-like almost black hyperpigmentations within the lesion. C: Detail of photograph shown in B illustrating strip-like and hyperpigmented parts of the lesion that are irregularly distributed within the tumor.
IPRS-7-04-g-002.jpg
PMC6073164_01_IPRS-7-04-g-002.jpg
F2
When the lesion was exposed, a black pigmentation became apparent, which was partially arranged in a stripe-like pattern and frayed at the edges (Figure 2 (Fig. 2)).
Histology of melanotic neurofibroma depicting clustered and scattered pigmented cells in H&E stain. Tumor cells react with antibodies against S100-protein and melan-A, note the typical wavy contours of the cells in the immunohistochemistry (Scale=50 microm).
IPRS-7-04-g-003.jpg
PMC6073164_01_IPRS-7-04-g-003.jpg
F3