PMC5523508_01
Preoperative (a) and postoperative (b) T1-contrasted magnetic resonance imaging demonstrates nodular enhancement and subsequent complete resection of the nodule
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F1
Surveillance MRIs demonstrated progressive nodular enhancement of the lesion [Figure 1a]. The patient subsequently underwent gross total resection of the mass and adjacent seizure onset zone [Figure 1b].
Hematoxylin and eosin (H and E) stained sections from 1982 at x100 (a) show a round-cell glial lesion with microcystic features and myxoid change consistent with an oligodendroglioma. At x400 (b), there are neurons floating in mucinous pools, a distinctive feature of dysembryoplastic neuroepithelial tumor (DNET) that was not identified until 1988. H and E stained sections from 2013 show almost identical features, now widely recognized as characterizing a DNET (c, x100; d, x400)
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F2
Histopathological evaluation identified the characteristic features of DNET in both specimens [Figure 2].