PMC8521190_01
Clinical and histological features of patient 6, 7, and 14. (A) Patient 6, from left to right: Erythematous excoriated papules of the back; Erythematous crusty papule of the arm in which was performed skin biopsy; Dense superficial dermal infiltrate of myeloid cells (CD68+ monocytes and rare MPO+ cells) associated with lymphocytes compatible with CMML cutis (Hematoxylin-eosin-saffron; Original magnification respectively x30 and x400). (B) Patient 7, from left to right: papulonodular lesions of the hand and forearm; Dermal lymphohistiocytic infiltrate (Hematoxylin-eosin-saffron; Original magnification x25). (C) Patient 14, from left to right: violaceous pustular and ulcerated lesions; Dense dermal neutrophilic infiltrate with histiocytes (Hematoxylin-eosin-saffron; Original magnification respectively x25 and x150).
fimmu-12-715053-g001.jpg
PMC8521190_01_fimmu-12-715053-g001.jpg
f1
CMML cutis in three cases (patients 4, 6, and 11), and ECD associated with CMML cutis in two cases (patients 1 and 3), Kikuchi-Fujimoto disease in one case (patient 5), neutrophilic folliculitis in one case (patient 10), erythema nodosum in one case (patient 13), pyoderma gangrenosum in one case (patient 14), and extensive livedo reticularis with non-specific findings on skin biopsy in one case (patient 8) ( Tables 1 ,  2 ). Clinical and histological lesions are shown for patients 6, 7, and 14 ( Figure 1 ).