PMC9826623_01
(A) Chest radiograph obtained 5 years before presentation shows a large fibrotic mass in the right upper zone (red arrowhead) and bilateral small nodules with upper-zone predominance. Pleural effusion is not seen. (B) Chest radiograph at presentation reveals right massive pleural effusions. (C-F) Chest computed tomography reveals multiple pleural tumors (yellow arrowheads) and bilateral pleural effusions with right predominance, in addition to small nodules in the left upper pulmonary lobe and enlarged hilar and mediastinal lymph nodes with calcification:typical findings in silicosis. Images (C) and (D) show the lung window, and images (E) and (F) show the plain mediastinal window.
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Chest imaging revealed right massive pleural effusions and multiple pleural tumors, in addition to small silicotic nodules and enlarged hilar and mediastinal lymph nodes with calcification (Figure 1).
Thoracoscopy shows multiple protruding papillary lesions in the parietal pleura. White-colored plaque is also seen.
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B-cell lymphoma was confirmed pathologically (Figures 2 and 3). Brain and abdominal to pelvic computed tomography showed no tumor lesions, and the patient was diagnosed with primary pleural lymphoma.
(A) Pleural biopsy reveals lymphoma cells on hematoxylin and eosin stain (x20). (B) Immunohistological examination reveals lymphoma cells positive for CD20, (C) negative for CD3, and (D) negative for Epstain-Barr virus-encoded RNA. Thus, the patient is diagnosed with diffuse large B-cell lymphoma.
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B-cell lymphoma was confirmed pathologically (Figures 2 and 3). Brain and abdominal to pelvic computed tomography showed no tumor lesions, and the patient was diagnosed with primary pleural lymphoma.