PMC4162075_01
Large palpable mass in the left thigh of patients associated with erythema of the adjacent skin
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F1
A case is presented of a 31-year-old female who complained of a painless, growing, palpable mass in her left thigh, associated with erythema of the adjacent skin [Figure 1].
Sagittal T1-weighted images (a) and T2-weighted images (b) Show a fusiform shape of a slightly isointense to muscle intensity on T1 images and homogenously hyperintense on T2 images
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F2
On MRI, the tumor showed an isointense signal on T1-weighted images and high-signal intensity on T2-weighted images, suggestive of myxoma [Figures 2 and 3].
Coronal T2-weighted images show a well-defined homogeneous mass lesion
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F3
On MRI, the tumor showed an isointense signal on T1-weighted images and high-signal intensity on T2-weighted images, suggestive of myxoma [Figures 2 and 3].
Giant encapsulated tumor after resection, having no adhesion to the adjacent tissue or vascular involvement
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F4
There was no adhesion to the adjacent tissue or vascular involvement [Figure 4].
On microscopic examination, a combined proliferation of all the elements of a peripheral nerve (axons, schwann cells, and fibroblasts) are seen, most have elongated nuclei, with wavy serpentine configuration and a pointed end (H and E, x100)
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F5
In the specimen taken from the adjacent skin, hyperpigmentation of the basal layer with neurofibromatous change in the dermis was present [Figures 5 and 6].
In some areas, mucinous changes were prominent, which could be mistaken for myxoma or myxoid liposarcoma (H and E, x400)
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F6
In the specimen taken from the adjacent skin, hyperpigmentation of the basal layer with neurofibromatous change in the dermis was present [Figures 5 and 6].