PMC4329679_01
CT-guided percutaneous lung biopsy in a 56-year-old woman. The nodular lesion was close to a surgical clip (A, white arrow). Probe placement during cryoablation with subsequent iceball formation (B, C, arrow)
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F1
CT-guided percutaneous lung biopsy (Biopince, 18g x 11 cm, Angiotech, USA) was performed on the nodule, which was confirmed as metastatic by subsequent histological analysis. Cryoablation of the nodule was therefore performed [Figure 1].
Same patient as Figure 1. One month CT follow-up showing nodular evolution of the lesion with no misplacement of the surgical clips (A, B). Six month CT follow-up showing shrinkage and cavitation of the nodule (C, D)
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F2
Nodular evolution of the ablated lesion was noted at the 1-month CT follow-up and significant shrinkage of the nodule coupled with signs of central cavitation, indicating necrotic evolution of the area, was noted at the 6 month CT follow-up [Figure 2].
PMC4329679_02
CT-scan image of an 80-year-old man obtained in the axial plane showing a sub-pleural lung consolidation consistent with NSCLC, close to a surgical clip (A, white arrow). Two parallel probes were placed to perform cryoablation (B). PET scans performed before the procedure showing a high-metabolic lesion (C, D white arrow) and repeated 6 months after the procedure showing significantly reduced metabolic activity (E, F)
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F3
A PET scan at 6 months' follow-up showed a reduction in size of the malignant mass, coupled with a significant reduction in SUV (from 11.8 to 2.8) [Figure 3].
PMC4329679_03
CT scan image of a 38-year-old female patient affected by lung metastasis from a carcinoma of the pancreatic tail showing a nodule in the dorsal segment of the right superior lobe, close to the surgical clips positioned during the previous surgical interventions (A). 3 months follow-up CT scan showing dimensional reduction of the nodule (B)
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F4
A CT scan at 3 months' follow-up [Figure 4] and a PET CT scan at 6 months' follow-up showed dimensional reduction of the nodule and signs of central cavitation, indicating necrotic evolution of the area, coupled with a substantial reduction in SUV (3.8 vs. 9.9) and no signs of surgical clip misplacement.