PMC8426193_01
Rhizopus, lactophenol cotton blue prep, 10x (left hand surgical specimen).
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The bronchoalveolar lavage cytologic specimen, right lower lobe surgical specimen, and left hand surgical specimen all demonstrated pauciseptate hyphae of a zygomycete and the associated cultures grew a Rhizopus species (Fig. 1).
Intravascular and perineural hyphae, H&E, 10x (left hand surgical specimen).
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Notably, the hand surgical pathology noted hyphae present within vessels and around nerves (Fig. 2, Fig. 3), suggestive of vascular spread rather than cutaneous inoculation.