PMC5402326_01
MRI findings: irregular contrast enhanced lesion, localized at the cavernous sinus and extension to upper clivus, hypointense at T2, without restriction at the diffusion sequence, with no peripheral edema or brain tissue invasion
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F1
Magnetic resonance imaging (MRI) showed an irregular contrast-enhanced lesion on the right cavernous sinus, causing a slight mass effect in the brainstem [Figure 1], with irregular borders, which the radiology assessment concluded as a meningioma.
(a) Scalp histology: pleomorphic large cell neoplasia infiltrating subepithelial soft tissue (b) Scalp immunohistochemistry: epithelial neoplasia consistent with adenocarcinoma, breast or gynecological region are considered as possible primary sites - positive for estrogen receptors (c) Breast histology: invasive ductal carcinoma, Nottingham 2 (d) Breast immunohistochemistry: positivity for estrogen and progesterone receptors
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F2
An invasive ductal carcinoma with positivity to estrogen and progesterone receptors was diagnosed [Figure 2].