PMC3219241_01
Chest and brain computerized tomography on days 1, 12, 19, 28, and 34. Aspiration pneumonitis with pulmonary contusion was shown on day 1. Black arrows, multiple lesions of fungus infection in both the lung and the brain. White arrows, progression of encephalomalacia in the left frontal lobe.
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F1
In view of aspiration pneumonitis (Figure 1, day 1), intravenous antibiotic treatment (tazocin, moxifloxacin hydrochloride and metronidazole) was started. Brain computerized tomography (CT) on day 12 indicated a focus of encephalomalacia in the left frontal lobe, which was thought to be the progress of brain contusion (Figure 1, day 12). On the same day, chest CT showed a pulmonary halo sign on the left upper lung (Figure 1, day 12), and voriconazole therapy was used because of high suspicion of invasive pulmonary fungal infection. On day 19, the brain CT showed signs of fungus infection (Figure 1, day 19). On day 34, enhanced CT imaging of the brain showed progression of multiple lesions of fungus infection (Figure 1, day 34).