PMC4531552_01
Clinical course of the patient during the 1st hospitalization. Agranulocytosis developed during prolonged vancomycin therapy and was rapidly resolved by the administration of G-CSF and by the discontinuation of vancomycin. Ceftazidime, which had been administered simultaneously with vancomycin until the agranulocytosis developed, was readministered to treat CAPD peritonitis during the 2nd hospitalization, but agranulocytosis did not develop (*HD; day of hospital admission).
kjim-19-1-58-11f1.jpg
PMC4531552_01_kjim-19-1-58-11f1.jpg
f1-kjim-19-1-58-11
On the 94th hospital day (the 82th of vancomycin and aztreonam therapy and the 36th day of ceftazidime therapy), agranulocytosis developed: the WBC count decreased to a nadir of 4,730/mm3, with 72% lymphocytes and no demonstrable neutrophils (Figure 1).