PMC5943896_01
(A) The primary tumor in the right lobe of the liver. (B) The liver after radiofrequency ablation.
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F1
The examination in our hospital found that there was a mass about 4.7 cm x 3.6 cm in right lobe of the liver with typical HCC radiological characteristics (Fig. 1A). The radiofrequency ablation was conducted on March 26, 2015 (Fig. 1B).
(A) The paraspinal metastasis first found (2015.6.22). (B and C) The paraspinal metastasis 3 months after sorafenib treatment (2015.9.16). (D and E) The paraspinal metastasis 8 months after sorafenib treatment (2016.3.3). (F and G) The paraspinal metastasis 8 months after apatinib treatment (2016.11.16).
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F2
T12 vertebra (Fig. 2A). The CT scan found that the paraspinal metastasis invaded the spinal cord (Fig. 2D and E). The CT scans showed that the paraspinal metastasis was nearly disappeared (CR) (Fig. 2F and G).
(A) The lung metastasis first found 3 months after sorafenib treatment (2015.9.16). (B) The lung metastasis 8 months after sorafenib treatment (2016.3.3). (C) The lung metastasis 8 months after apatinib treatment (2016.11.16).
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F3
Nevertheless, the patient developed lung metastasis 3 months later (Fig. 3A) and the paraspinal metastasis grew gradually (Fig. 2B and C). Besides, the lung metastasis grew bigger (Fig. 3B). The lung metastases were stable (SD) (Fig. 3C).