PMC6077610_01
MRI before cessation of fingolimod in September 2016 (upper row) and 19 days after infusion of rituximab (July 2017; lower row). Coronal (A/D ) and sagital (B/E) flair and coronal T2 (C/F) images show several new and enlarging lesions after switch to rituximab. Arrows indicate contrast enhancement on sagital T1 images (D/G).
CRINM2018-5190794.001.jpg
PMC6077610_01_CRINM2018-5190794.001.jpg
fig1
MRI showed approximately 50 contrast enhancing lesions throughout the cerebral hemispheres, mesencephalon, right upper and lower cerebellar peduncles, left cerebellar hemisphere, and corresponding to C3 and C5 in the spinal cord (Figure 1).