PMC7522575_01
Showing the first clinical presentation of the lesion.
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PMC7522575_01_gr1.jpg
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A 61 years old female patient, with a chief complaint of an intraoral white lesion covering the mucosa of the right cheek that appeared 2 years ago (Fig. 1).
Showing oral viral papillomatous lesion (H&E, x100), showing papillomatosis (blue arrow head), koilocytosis (black arrow) and dykeratotic figures (white arrow).
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PMC7522575_01_gr2.jpg
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The undertaken biopsy from the right buccal mucosa and histopathological examination revealed an oral squamous papilloma (Fig. 2).
Showing the lesion extending to the floor of the mouth.
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PMC7522575_01_gr3.jpg
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Clinical examination revealed that the lesion extended to involve the floor of the mouth (Fig. 3) and the extraoral skin of the right cheek (Fig. 4).
Showing moderately-differentiated squamous cell carcinoma (H&E, x100), showing some keratin pearls (white arrows).
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PMC7522575_01_gr5.jpg
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The postoperative pathological diagnosis was squamous cell carcinoma (SCC) grade II (Figs. 5, 6).
Showing moderately-differentiated squamous cell carcinoma (H&E, x400), showing mitotic figure (blue arrow) and prominent nucleoli (black arrow).
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PMC7522575_01_gr6.jpg
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The postoperative pathological diagnosis was squamous cell carcinoma (SCC) grade II (Figs. 5, 6).