PMC5846923_01
Radiograph of the right distal forelimb (dorsopalmar view) showing loose screws (red arrow) and associated soft tissue swelling (yellow arrow)
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Radiographs of the limb revealed significant lysis and soft tissue swelling around two loose screws at the previous surgical site (Figure 1).
(a) Haematoxylin and eosin photomicrograph (X 40) revealing a poorly defined, densely cellular tumour infiltrating through the dermis. (b) Haematoxylin and eosin photomicrograph (X 200) showing a monomorphic population of neoplastic round cells
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There was no evidence of epitheliotropism (Figure 2).
Immunohistochemistry against CD3, counterstained with haematoxylin (X 200). Many of the neoplastic cells exhibit moderate-to-strong cytoplasmic staining indicating a tumour of T lymphocyte origin
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Immunohistochemistry confirmed a predominant population of round cells exhibiting strong cytoplasmic positivity for CD3 antigen (Figure 3).
Photograph of the primary lesion at time of referral to Victorian Animal Cancer Care
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Two weeks later, the cat presented to Victorian Animal Cancer Care, Melbourne, Australia, where the primary lesion was ulcerated and swollen (Figure 4).
Photograph demonstrating progression of the primary lesion. The cat was euthanased on the day this photograph was taken
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Four weeks following commencement of chemotherapy, progressive disease was noted within the cutaneous lesion (Figure 5) and right axillary lymph node.