PMC3987762_01
Tc-99m labeled human serum albumin scintigraphy showed intense activity in ascending colon on day one.
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Tc-99m labeled human serum albumin scintigraphy showed faint bowel radioactivity that was first noticeable in the right side of abdomen at five hours became highly intense in the ascending colon after 24 hours (Fig. 1).
The CT scan of the abdomen showed a thick walled lesion filled with fluid and small amount of gas closely related to proximal jejunum and mesentery.
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The patient experienced increasing abdominal pain; and the urgent contrast computed tomography (CT) of the abdomen was performed and revealed a large (11.4 x 7.2 x 8.1 cm) lobulated thick walled lesion filled with fluid and small amount of gas closely related to proximal jejunum and mesentery (Fig. 2).
(A) Lower power field showed spindly tumor cells with focal storiform pattern and nuclear palisading. (B) High power field showed tumor cells possessing pink cytoplasm and oval nuclei with distinct to prominent nucleoli and mild to moderate nuclear pleomorphism. (C) Immunohistochemical study showed that the tumor cells were diffusely and strongly positive for c-kit (CD117).
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The histology revealed the tumor consisted of packets of spindle cells invading the intestinal mucosa and the tumor cells had ovoid nuclei, prominent nucleoli and pink cytoplasm (Fig. 3A). Immunostatin for c-kit was strongly positive (Fig. 3C).