PMC7104315_01
Ultrasound image showing 9 mm right testicular calcified lesion.
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fig1
An ultrasonography evaluation revealed grade 3 left varicocele and an incidental 9 mm right testicular calcified lesion (Figure 1).
Well-circumscribed mass of LCCSCT (H&E stain; x10).
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Histopathological assessment findings showed a well-circumscribed, encapsulated tumor composed of amorphous calcified areas, surrounded by tumor cells (Figure 2).
Psammomatous calcification within the neoplastic nests (H&E stain; x10).
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Tumor cells were large and oval to polygonal in shape, with a highly eosinophilic granulated cytoplasm (Figure 3).
LCCSCT shows a myxoid stromal component (H&E stain; x20).
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fig4
Nuclear pleomorphism was prominent, but mitotic activity was rare and there was no evidence of necrosis (Figure 4).
LCCSCT cells show strong inhibin expression (x10).
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fig5
Tumor cells were positive for inhibin alpha, epithelial membrane antigen (EMA), calretinin, S-100, MART-1, and vimentin and negative for CD99 (AKA MIC2), pan-cytokeratin (AE1/3), synaptophysin, chromogranin, CK8/18, and CD10 (Figures 5-9).
LCCSCT cells show intense calretinin expression (x10).
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fig6
Tumor cells were positive for inhibin alpha, epithelial membrane antigen (EMA), calretinin, S-100, MART-1, and vimentin and negative for CD99 (AKA MIC2), pan-cytokeratin (AE1/3), synaptophysin, chromogranin, CK8/18, and CD10 (Figures 5-9).
LCCSCT cells show intense vimentin expression (x4).
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fig7
Tumor cells were positive for inhibin alpha, epithelial membrane antigen (EMA), calretinin, S-100, MART-1, and vimentin and negative for CD99 (AKA MIC2), pan-cytokeratin (AE1/3), synaptophysin, chromogranin, CK8/18, and CD10 (Figures 5-9).
LCCSCT cells show strong Mart-1 expression (x20).
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fig8
Tumor cells were positive for inhibin alpha, epithelial membrane antigen (EMA), calretinin, S-100, MART-1, and vimentin and negative for CD99 (AKA MIC2), pan-cytokeratin (AE1/3), synaptophysin, chromogranin, CK8/18, and CD10 (Figures 5-9).
LCCSCT cells show strong S100 expression (x20).
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fig9
Tumor cells were positive for inhibin alpha, epithelial membrane antigen (EMA), calretinin, S-100, MART-1, and vimentin and negative for CD99 (AKA MIC2), pan-cytokeratin (AE1/3), synaptophysin, chromogranin, CK8/18, and CD10 (Figures 5-9).