PMC7591986_01
Right testicle. On cut surface shows a poorly defined 1.8 cm paratesticular tumor.
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The gross examination showed a testicle with 3.5 cm in diameter, and the cut surface presented a poorly defined tan tumor of 1.8 cm, occupying the vaginal tunica and epididymis and infiltrating the testicular parenchyma (Figure 1).
Cystic-looking tumor, with intermixed papillary projections.
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In histological sections, a cystic neoplasm was observed, with hierarchical papillary projections, covered by one or several epithelial layers of columnar and hobnail cells with moderate atypia and scant mitosis (Figures 2-4).
Hierarchical papillae with stroma of edematous appearance. 5x HyE.
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fig3
In histological sections, a cystic neoplasm was observed, with hierarchical papillary projections, covered by one or several epithelial layers of columnar and hobnail cells with moderate atypia and scant mitosis (Figures 2-4).
Papillae covered by several layers of columnar cells with moderate atypia. HyE 40x.
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fig4
In histological sections, a cystic neoplasm was observed, with hierarchical papillary projections, covered by one or several epithelial layers of columnar and hobnail cells with moderate atypia and scant mitosis (Figures 2-4).
Epithelial membrane antigen.
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Immunohistochemical reactions were performed, resulting PAX-8, epithelial membrane antigen (EMA), and cytokeratin 7 positive (Figures 5-7), confirming the diagnosis of borderline serous tumor.
Cytokeratin 7.
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Immunohistochemical reactions were performed, resulting PAX-8, epithelial membrane antigen (EMA), and cytokeratin 7 positive (Figures 5-7), confirming the diagnosis of borderline serous tumor.
PAX8.
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Immunohistochemical reactions were performed, resulting PAX-8, epithelial membrane antigen (EMA), and cytokeratin 7 positive (Figures 5-7), confirming the diagnosis of borderline serous tumor.
(a, b and c) The tumor was negative for calretinin, estrogen, and progesterone receptors, respectively.
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fig8
The tumor cells were negative for calretinin, estrogen, and progesterone receptors (Figure 8).