PMC4706389_01
FISH (fluorescence in situ hybridization) probes for chromosomes 21 (red signal), 18 (yellow or fused red/green signal), and 12 (green signal) were used to identify cells with trisomy 21 (left) and both trisomy 18 and trisomy 21 (right).
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Abbott Park, Illinois, USA; Fig. 1). A total of 500 interphase cells from the cord blood sample was examined, and a fluorescence pattern consistent with trisomy 21 was observed in all.