PMC4900055_01
59-year-old female with adenocarcinoma, clear-cell variant. T2 fat-saturated MR image in the coronal plane demonstrates a mass (*) inferior to the urinary bladder (#).
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The mass was T2 hyperintense (Fig. 1), T1 hypointense (Fig. 2), and demonstrated slightly heterogeneous enhancement (Figure 3, Figure 4).
59-year-old female with adenocarcinoma, clear-cell variant. T1 fat-saturated postcontrast MR image in the sagittal plane demonstrates heterogeneous enhancement of the periurethral mass (*) with possible vesicular invasion (arrow).
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The mass was T2 hyperintense (Fig. 1), T1 hypointense (Fig. 2), and demonstrated slightly heterogeneous enhancement (Figure 3, Figure 4). An incomplete fat plane was identified between the mass and the urinary bladder, with possible vesicular invasion identified on the sagittal images (Fig. 3).
59-year-old female with adenocarcinoma, clear-cell variant. Axial, T1 fat-saturated postcontrast MR image demonstrates heterogeneous enhancement of the infiltrative periurethral mass (*).
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The mass was T2 hyperintense (Fig. 1), T1 hypointense (Fig. 2), and demonstrated slightly heterogeneous enhancement (Figure 3, Figure 4).
59-year-old female with adenocarcinoma, clear-cell variant. H&E stained photomicrograph at 40x magnification demonstrates clear-cell adenocarcinoma in a tubular pattern. Note the clear cytoplasm.
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Surgical pathology revealed a 3.6-cm, poorly differentiated, urethral adenocarcinoma, clear-cell variant (Figure 5, Figure 6).
59-year-old female with adenocarcinoma, clear-cell variant. At 60x magnification, hobnail cells with nuclear hyperchromasia, pleomorphism, and nucleoli are visible (green arrowheads).
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Surgical pathology revealed a 3.6-cm, poorly differentiated, urethral adenocarcinoma, clear-cell variant (Figure 5, Figure 6).