PMC5562108_01
Gross appearance of well-circumscribed encapsulated mass.
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Abdominal ultrasonography (USG) revealed a well circumscribed subcutaneous lesion present in front of the xiphoid process, oval in shape measuring 38 x 34 mm with tissue density and peripheral calcifications (Fig. 1). Grossly, the tumor appeared pearly white with a lobular contour confined by a thin capsule measuring about 40 x 35 mm in diameter (Fig. 1, Fig. 2).
Fibrous septae giving a lobular appearance (HEx100).
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Dense fibrous septa extended from the capsule into the tumor, leading to a lobulated appearance (Fig. 3).
Fibrous septae that are focally ossified (HEx100).
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Spicules of bone with focal osteoblast rimming were found in the central zones of the tumor close to fibrous septa (Fig. 4).
Abundant myxoid matrix separates nests and cords of tumour cells (HEx200).
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Some areas were less cellular and lobules are made of short spindle cells surrounded by abundant fibro-myxoid matrix (Fig. 5).
Foci of chondroid metaplasia (HEx200).
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Foci of chondroid metaplasia were seen (Fig. 6).
uniform ovoid with round vesicular nuclei, discernable nucleoli without mitotic activity (HEx400).
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The nuclei were small, oval shaped, non-pleomorphic and vesicular (Fig. 7).
Diffuse and intense staining with Ps100 (IHCx200).
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Immunohistochemically, the tumor cells were uniformly positive for S100 (Fig. 8) and focally positive for actin smooth muscle and AE1/AE2.