PMC9114742_01
PMC9114742_02
MRI and pathological images. (A, B) Five years before the operation: Coronal MRI and enhanced MRI images indicated the sellar lesions with a size of approximately 21.0 x 14.5 x 12 mm had cystic structures and was inhomogenously enhanced. (C, D) Three months before the operation: Coronal MRI and enhanced MRI images indicated the sellar lesions with a size of about 37 x 35 x 24 mm had variable signal intensity and multiple apoplectic events. (E) Hematoxylin-eosin (H&E) staining indicated the mild cell morphology with rare nuclear division; immunohistochemical staining indicated that the tumor cells were positive for (F) Vimentin, (G) SMA, (H) SYN, (I) h-caldesmon, (J) Desmin, (K) Collagen IV, and (L) CD34. Magnification, x200; Bar = 100 mum.
fendo-13-895054-g001.jpg
PMC9114742_02_fendo-13-895054-g001.jpg
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The lesion had cystic structures and was heterogeneously enhanced, suggesting a "macroadenoma" (Figures 1A, B). The high-resolution contrast enhanced MRI revealed a giant hetereogenous sellar mass with multiple apoplectic events, measuring 37 x 35 x 24 mm in size (Figures 1C, D). Histopathological examination revealed mild cell morphology with rare nuclear division (Figure 1E) . Immunohistochemical (IHC) staining indicated tumor cells positive for Vimentin (Figure 1F), SMA (Figure 1G), SYN (Figure 1H), h-caldesmon (Figure 1I), Desmin (weak, Figure 1J), Collagen IV (Figure 1K), and CD34 (vascular, Figure 1L).