PMC7217305_01
Comparison of cross-sectional chest CT scan images of the patient with MDR-TB at different time points before and after taking effective treatment regimens. (A) Three months before effective treatment regimens showing multiple lesions and cavities in bilateral lungs (black and white arrowheads) at two cross-sections (A1 and A2); (B) Two months after effective treatment regimens showing absorption of multiple lesions and cavities in bilateral lungs (black and white arrowheads) at two cross-sections (B1 and B2); (C) Eight months after effective treatment regimens showing multiple lesions and cavities in bilateral lungs disappeared (more obvious in the right lung), and fibrosis remained unchanged (black and white arrowheads) at two cross-sections (C1 and C2); and (D) Seven months after the 20-month treatment using effective regimens showing multiple lesions and cavities in bilateral lungs disappeared (more obvious in the right lung) and pulmonary fibrosis remained unchanged (black and white arrowheads) at two cross-sections (D1 and D2). CT, computed tomography; MDR-TB, multidrug-resistant tuberculosis.
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Computed tomography (CT) scans of the chest showed bilateral pulmonary TB with cavities, bilateral pleural thickening, and enlarged lymph nodes in the upper mediastinum (Figure 1, A1 and A2). Chest CT scans of the patient performed two months after starting the new treatment showed decreased lesions in bilateral lungs (Figure 1, B1 and B2), and those performed at eight months after starting the new treatment showed that lesions and cavities in bilateral lungs disappeared while pulmonary fibrosis remained unchanged, indicating the treatment was successful (Figure 1, C1 and C2). Follow-up chest CT scans performed seven months after the completion of the 20-months of treatment showed that patient's lung lesions and fibrosis remained unchanged (Figure 1, D1 and D2), and sputum cultures were negative for M.tuberculosis.