PMC5859826_01
Patient bone marrow a aspirate and b biopsy. a Aspirate demonstrates spicules composed of stromal components, but lacking trilineage marrow elements. b Biopsy reveals a hypocellular marrow with global trilineage hypoplasia
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Fig1
On day 48 a bone marrow biopsy was performed, which showed a markedly hypocellular marrow (< 10%) with trilineage hypoplasia (Fig. 1).
Trends in patient a hemoglobin, b neutrophils and c platelets over time
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Fig2
The patient responded well to the steroid therapy, with a marked recovery in both hemoglobin and absolute neutrophil count (Fig. 2), providing support for the presumed diagnosis.