PMC3617864_01
Increase in case-fatality rate (CFR) with increasing number of severe malaria features, Kampala, Uganda. CFRs are shown for 855 children with one or more combinations of the following features: cerebral malaria, lactic acidosis, severe anemia, severe thrombocytopenia, or hyper-parasitemia. The x-axis separates children into five groups based on an increasing number of co-existing severe malaria features present in combination. The groups show an increasing median CFR. The size of each bubble indicates the number of persons ranging from n = 558 for the single feature of severe anemia (lower left) to n = 4 for all five features simultaneously present (upper right).
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F3
The relationship between CFR and the number of features present in the same patient are shown in Figure 3.