PMC3971555_01
Large cystic spaces and cribriform structures were present throughout the lesion (x100).
CRIPA2014-982432.001.jpg
PMC3971555_01_CRIPA2014-982432.001.jpg
fig1
Mucous cells were frequently seen (Figures 1, 2, and 3).
Apocrine metaplasia was evident throughout the lesion (x400).
CRIPA2014-982432.002.jpg
PMC3971555_01_CRIPA2014-982432.002.jpg
fig2
Mucous cells were frequently seen (Figures 1, 2, and 3).
Mucous cells were frequently seen (x400).
CRIPA2014-982432.003.jpg
PMC3971555_01_CRIPA2014-982432.003.jpg
fig3
Mucous cells were frequently seen (Figures 1, 2, and 3).
Immunohistochemical examination with alphaSMA confirmed the presence of a peripheral myoepithelial layer around all ductal structures (x400).
CRIPA2014-982432.004.jpg
PMC3971555_01_CRIPA2014-982432.004.jpg
fig4
Myoepithelial cells, surrounding ductal elements, demonstrated immunoreactivity for alphaSMA (Figure 4).
Less than 1% of lesional cells were immunoreactive for Ki-67 antibody (x400).
CRIPA2014-982432.005.jpg
PMC3971555_01_CRIPA2014-982432.005.jpg
fig5
Immunohistochemical examination with Ki-67 revealed less than 1% positivity in lesional cells (Figure 5).