PMC5765241_01
A and B: Pelvic and C-spine x-rays showing sacroiliitis and bamboo spine, respectively. C and D: Spine MRI images showing high signal intensity on T2WI from T10 to the conus medullaris at the first attack (arrowhead). E: Brain MRI image showing high signal intensity on T2WI in the left occipital lobe at the first attack. F and G: Spine MRI image showing high signal intensity on T2WI from T1 to T3 at the second attack (asterisk). H: Brain MRI image showing high signal intensity on T2WI in the right dorsal medulla at the third attack (arrow). MRI: magnetic resonance imaging, T2WI: T2-weighted imaging.
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F1
She had been diagnosed with human leukocyte antigen B27 (HLA-B27)-negative AS with characteristic back pain and bilateral sacroiliitis (Fig. 1A and B). Magnetic resonance imaging (MRI) showed high signal intensity within the spinal cord from T10 to the conus medullaris on T2-weighted imaging (T2WI), predominantly involving the central portion of the spinal cord (Fig. 1C and D). Brain MRI showed high signal intensity in the white matter of the left occipital lobe on T2WI, without gadolinium enhancement (Fig. 1E). Follow-up MRI showed high signal intensity within the spinal cord from T1 to T3 on T2WI (Fig. 1F and G). Brain MRI revealed a tiny lesion at the dorsal medulla (Fig. 1H).