PMC8593038_01
(A) Clinical image of this patient before treatment; (B) Histopathological examination by Periodic acid-Schiff stain and Methenamine silver stain showing a type of infectious granuloma, abundant blastoconidia, and hyphae elements (yellow arrows indicated); (C) Clinical image of this patient after treatment; (D) Fungal culture showing yeast-like colonies and budding spores under microscope.
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Varisized nodes, superficial ulcers, and scales could be observed within the involved region ( Figure 1A ). In addition, Periodic acid-Schiff (PAS) and Gomori-Grocott methenamine silver (GM) stains showed a type of infectious granuloma and abundant blastoconidia ( Figure 1B ). Figure 1D ). The itraconazole doses was reduced to 0.1 mg each day at 5 months and ended after 6 months of treatment due to the complete relief ( Figure 1C ).