PMC3015893_01
Ultrasound examination: hypoechoic mass 43/40 mm in the left adrenal gland.
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F1
The abdominal ultrasound revealed an increased, nonhomogenous right adrenal gland 36/33 mm, and a left adrenal gland containing a hypo-echoic tumor 43/40 mm (Figure 1).
(A) Histopathological examination - hematoxilin eosine, 4x. Tumor mass consists of conjunctive proliferation, with fascicular architecture and isolated nuclear palisades. (B) Immunohistochemistry - KI67 staining, 20x. Rare positive cells (<1%). (C) Immunohistochemistry - S100 staining, 4x. Tumor cells are positive to this marker. (D) Immunohistochemistry - SMA staining, 4x. Tumor cells are negative, but blood vessels are diffusely positive.
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F2
S100 staining was positive diffusely across the tumor. SMA (smooth muscle actin) was negative in tumor cells, while positive in blood vessels (Figure 2).