PMC5459349_01
Macroscopic appearance of the tumor.
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On gross pathological examination, an 11.5 x 7.5 x 7 cm solid lobulated mass, which was originated from the parietal layer of anterior tunica vaginalis and growed into scrotal sac was noted (Figure 1).
Hypocellular and highly myxoid lesion consisting of small spindle cells and blood vessels of varying sizes. A black arrow in (a) points to the mesothelial lining of parietal tunica vaginalis ((a) H&E: x100; (b) H&E: x40; (c) H&E: x200).
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Microscopical examination showed that the lesion was hypocellular and composed of short spindle cells within abundant myxoid extracellular matrix, which was collagenous in some areas (Figure 2).
Neoplastic cells showing diffuse (a) estrogen receptor, (b) CD34 and (c) focal desmin immunoreactivity (immunohistochemistry: (a) anti-ER Ab, x200; (b) anti-CD34 Ab, x400; (c) anti-desmin Ab, x200).
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Immunohistochemical studies revealed diffuse and strong expression of CD34, estrogen receptor (ER) and progesterone receptor (PR) by neoplastic cells (Figure 3).