PMC3837489_01
Blasts with cytoplasmic blebs and a basophil.
can-7-375fig1.jpg
PMC3837489_01_can-7-375fig1.jpg
figure1
Some of the blasts showed cytoplasmic blebs or projections (Figure 1).
Abnormal, large platelets.
can-7-375fig2.jpg
PMC3837489_01_can-7-375fig2.jpg
figure2
Individual platelets showed marked variation in size (Figure 2).
Abnormal megakaryocytes and marrow fibrosis.
can-7-375fig3.jpg
PMC3837489_01_can-7-375fig3.jpg
figure3
Bone marrow aspiration and biopsy showed increased abnormal megakaryocytes and bone marrow fibrosis (Figure 3).
Megakaryocytes with pleomorphic nuclei.
can-7-375fig4.jpg
PMC3837489_01_can-7-375fig4.jpg
figure4
Monolobated and multinucleated megakaryocytes with hyperchromatic and pleomorphic nuclei were seen (Figure 4) and showed strong positive staining for CD 61 (Figure 5).
Strong CD 61 positivity in megakaryocytes.
can-7-375fig5.jpg
PMC3837489_01_can-7-375fig5.jpg
figure5
Monolobated and multinucleated megakaryocytes with hyperchromatic and pleomorphic nuclei were seen (Figure 4) and showed strong positive staining for CD 61 (Figure 5).