PMC5763101_01
Soft fluctuant swelling in the right posterior part of the palate. Spontaneous bleeding was noted from the lesion.
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fig1
Adjacent teeth were intact and firm (Figure 1).
(a) Low-power view showing neoplastic glandular epithelial cells (*) separated from the overlying mucosal parakeratinized stratified squamous epithelium. Oncocytic cells (#) intermixed with the cellular elements of mucous, epidermoid, and intermediate cells (magnification 4x). (b) Tumour mass showing multiple large cystic spaces (magnification 10x). (c) Cystic spaces lined by mucous cells (magnification 40x). (d) Oncocytic metaplasia evidenced by the presence of oncocytes (magnification 10x). (e) Cells with granular eosinophilic cytoplasm arranged in an organoid/alveolar pattern and supported by thin fibrous connective tissue septa (magnification 40x).
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fig2
Oncocytic cells were also seen to be intermixed with the cellular elements of mucous, epidermoid, and intermediate cells (Figure 2). On higher magnification, the lesional tissue (tumour mass) was seen to exhibit large cystic spaces that were lined by mucous, epidermoid, intermediate, spindle-shaped, and few clear cells (Figures 2 and 2). Oncocytic metaplasia was evidenced as extensive areas of polyhedral cells with granular eosinophilic cytoplasm arranged in an organoid/alveolar pattern and supported by thin fibrous connective tissue septa (Figures 2 and 2).