PMC3965936_01
Upper digestive endoscopy showing numerous injuries on the esophageal surface that were yellow-whitish in color, pleomorphic, and isolated small circular plaques with central erosions and even depression with hyperemia at baseline; these injuries were more prominent in the distal third of the esophagus, indicating infectious esophagitis.
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fig1
Anatomic pathological examination of the esophagus showing ulceration with presence of multinucleated cells with overlapping nuclei and ground-glass aspect, consistent with herpetic infection (hematoxylin-eosin).
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fig2
Immunohistochemical study of the esophagus's fragment showing positivity to herpes simplex virus type 1.
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fig3
An immunohistochemical study of the patient's esophagus revealed that the patient was positive for herpes virus type 1 (Figure 3).