PMC9309468_01
Plain CT demonstrated a hyperdense lesion with multiple calcifications and proliferating adjacent blood vessels in the left parietal lobe. (A) T1-weighted MRI showed hypointense irregular abnormal cortical and subcortical regions. (B) T2-weighted MRI demonstrated a hyperintense mass. (C) MR post gadolinium enhancement showed enhanced pia mater and cortex. (D) Magnetic resonance spectroscopy (MRS) revealed decreased NAA and increased Cho in the lesion. The Cho/Cr ratio was markedly elevated (3.94), while the NAA/Cr ratio was reduced (0.43) in the lesion area (E).
fneur-13-912728-g0001.jpg
PMC9309468_01_fneur-13-912728-g0001.jpg
F1
No personal or family history of neurological diseases was reported, but plain computed tomography (CT) demonstrated a hyperdense lesion with multiple calcifications and proliferating adjacent blood vessels in the left parietal lobe (Figure 1A). MRI demonstrated a hyperintense mass (Figure 1C). MR post gadolinium enhancement showed enhanced pia mater and cortex (Figure 1D). Furthermore, MRS revealed decreased NAA and increased Cho in the lesion (Figure 1E).
Surgical microscopic examination showed an ill-defined mass with a grayish-yellow surface. The overlying dura was involved (black arrow) and the surrounding tissue was slightly edematous (A,B). Biopsy showed a diffused proliferation of spindle and oval cells with some psammoma bodies present in the cortex (C,D).
fneur-13-912728-g0002.jpg
PMC9309468_01_fneur-13-912728-g0002.jpg
F2
The overlying dura was determined to be involved, and the surrounding tissues were slightly edematous (Figures 2A,B). Extensive spindle-shaped cells were found to be arranged in a whorled pattern surrounding the vessels, and syncytial cells were present in local regions (Figures 2C,D).