PMC4150341_01
MRI right wrist and hand: (a) Well-defined lobulated lesion measuring 5 x 4 x 3 cm in the radial aspect of the wrist, appearing T2 hyperintense, with a peripheral T2 hypointense rim, slightly hyperintense on T1 W1 with a central hypointense area, with no significant post contrast enhancement; (b) the lesion was closely abutting the scaphoid and trapezoid. Erosions were noted in the lunate. FNA: (c) predominantly chondromyxoid substance showing chondrocytes (c) inset showing chondrocytes with mild atypia. (H and E, x400), (d) showing clusters ofchondrocytes with vesicular nucleus and moderate amount of basophilic nucleus (H and E, x400)
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F1
T2 hyperintense, with a peripheral T2 hypointense rim, slightly hyperintense on T1 W1, with a central hypointense area, with no significant post-contrast enhancement [Figure 1a]. The lesion was closely abutting the scaphoid and trapezoid [Figure 1b]. Fine needle aspiration (FNA) performed on the lesion showed predominantly cartilaginous tissue fragments with abundant chondromyxoid substance [Figure 1c]. The fragments showed chondrocytes with mild atypia [Figure 1c]. The background showed numerous red blood cells [Figure 1d].
Macroscopic features of the tumor: (a) External surface, the swelling is 5 x 4 x 3.5 cm, well-defined, lobulated, and glistening white. (b) On cut section white firm areas noted. Microscopic details of tumor: (c) Lobules of mature hyaline cartilage seen. The chondrocytes show mild cytological atypia and areas of myxoid change (H and E, x100), and (d) calcification noted (H and E, x100)
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F2
On gross examination, the swelling was 5 x 4 x 3.5 cm, well-defined, lobulated, hard, and glistening white [Figure 2a]. On cut section, white firm areas were noted [Figure 2b]. At the periphery focal myxoid areas [Figure 2c] were seen, with spotty calcification and small areas of enchondral ossification [Figure 2d].