PMC6010585_01
Cafe au lait spot (left), cutaneous neurofibroma (center) and axillary freckles (right).
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Chest CT (axial reconstruction, pulmonary window) revealing patchy areas of centrilobular ground-glass micronodules.
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(Left): Haematoxylin and Eosin (H&E) stain, 100x magnification. Arteriole with concentric and eccentric intimal thickening by fibrosis; pneumocyte hyperplasia and accumulation of macrophages, mostly along bronchovascular bundles.. (Right): Haematoxylin and Eosin (H&E) stain, 100x magnification. Intense macrophage accumulation in alveolar spaces, predominantly in the centrilobular regions.
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It was also visible an accumulation of macrophages along bronchovascular bundles but also at alveolar spaces and hyperplasia of type II pneumocytes (Fig. 3).