PMC4276276_01
Pedigree of symptomatic JID. The pattern of inheritance observed appears most consistent with an autosomal dominant mutation.
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The patient's family history was significant for an extensive history of JID (Fig. 1).
(a) The proximal 100 cm of jejunum, with dense diverticulosis. (b) H&E stain of a representative diverticulum demonstrates all bowel layers present. (c, d) Desmin staining demonstrates the muscularis mucosa (*) and muscularis propria (x), consistent with true diverticulum.
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We performed a laparoscopic resection of the proximal 100 cm of jejunum, with eight additional stapled diverticulectomies in the distal jejunum (Fig. 2a). The specimen was sent for pathology, where H&E staining demonstrated both muscularis mucosa and muscularis propria, consistent with true diverticula (Fig. 2b). Additional staining for desmin re-demonstrated the presence of muscularis mucosa and muscularis propria (Fig. 2c and d).