PMC10355039_01
PET scan of the lung before (down) and after (up) treatment showed near complete resolution of multiple lung FDG-avid nodules.
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PET (Fig. 1). PET scan also showed FDG-avid, solitary liver lesion (Fig. 2), and multiple bone lesions (Fig. 3). Four months later, she has reduced smoking to five to ten cigarettes per day, her symptoms have decreased, and a repeat PET/CT scan showed a nearly complete resolution of multiple lung lesions (Fig. 1), resolution of focal liver uptake (Fig. 2), and the L4 bone lesion (Fig. 3).
PET scan of the liver before (down) and after (up) treatment showing resolution of focal liver uptake.
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PET (Fig. 1). PET scan also showed FDG-avid, solitary liver lesion (Fig. 2), and multiple bone lesions (Fig. 3).
PET scan of the vertebral bone (down) and after (up) treatment showing near complete resolution of the L4 bone lesion.
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Four months later, she has reduced smoking to five to ten cigarettes per day, her symptoms have decreased, and a repeat PET/CT scan showed a nearly complete resolution of multiple lung lesions (Fig. 1), resolution of focal liver uptake (Fig. 2), and the L4 bone lesion (Fig. 3).
Langerhans cell histiocytes infiltrate the lung parenchyma with occasional eosinophils in the background (a), CD68 (b), CD1a (c), and Langerin (d) (hematoxylin-eosin, original magnification x400 [a] and immunohistochemical stains, original magnification x400 [b-d]).
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Histopathological examination of the pulmonary nodule (Fig. 4) revealed features consistent with Langerhans histiocytosis.