PMC3281777_01
Ectrodactyly of hands.
1752-1947-6-35-1.jpg
PMC3281777_01_1752-1947-6-35-1.jpg
F1
Both hands showed a classic lobster claw deformity: her middle digit was absent and the remaining four fingers were parted, two on either side, the cleft almost dividing the palm into two (Figure 1).
Ectrodactyly of feet.
1752-1947-6-35-2.jpg
PMC3281777_01_1752-1947-6-35-2.jpg
F2
The second and third toes of both her feet were missing and the remaining three toes were divided by a cleft into two parts, the big toe on one side and the other two toes on the other side (Figure 2).
Computed tomography of her brain showing holoprosencephaly with absent corpus callosum.
1752-1947-6-35-3.jpg
PMC3281777_01_1752-1947-6-35-3.jpg
F3
Computed tomography of her brain showed HPE and corpus callosum dysgenesis (Figure 3).