PMC7734475_01
Nailfold capillary findings. Nailfold video-capillaroscopy (NVC; optipix capillaroscopy, produced by Optilia Instruments AB, Sollentuna, Sweden) was performed from the index finger to the little finger of both hands. L2: left index finger; L3: left middle finger; L4: left ring finger; L5: left little finger; R2: right index finger; R3: right middle finger; R4: right ring finger; R5: right little finger. The figures for nailfold capillary microscopic examination are shown with a magnification of x200. (a) The NVC test was performed when SLE was diagnosed. NVC showed many enlarged capillaries, giant capillaries and haemorrhages. (b) The test was conducted 3 months after the commencement of HCQ treatment. Giant capillaries had disappeared, but some enlarged capillaries and haemorrhage remained. Ramification was noted. (c) These are the test results 14 months after the introduction of HCQ treatment. Enlarged capillaries had largely disappeared. Only mild haemorrhage was detected. Most capillaries had normalized.
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Nailfold video-capillaroscopy (NVC) revealed nailfold capillary (NFC) abnormalities (Fig. 1a). NVC indicated improvement of the NFC abnormalities (Fig. 1b). After 14 months, the lymphopenia, hypocomplementaemia and NFC were normalized (Fig. 1c).  