PMC3617967_01
a A discrete ulceration at the ileocecal valve in August 1989. b A deep discrete ulceration at the terminal ileum in October 1996. c A large ulceration at the ileum end in November 2003. d Chest CT showed irregular consolidation and ground-glass opacity in March 2003. e An ulcer scar at the ileocecal valve and ileum end in December 2006.
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F1
Total colonoscopy revealed discrete and round ulceration at the ileocecal valve with moderate inflammation (fig. 1a). After discharge, treatment of salazosulfapyridine (or mesalazine) was continued, but the discrete ulceration at the terminal ileum relapsed frequently once every 1 or 2 years from 1989 to 2004 (fig. 1b, c, fig. 2). In 2002, the patient had fever and hemoptysis, and chest CT showed irregular consolidation and ground-glass opacity in March 2003 (fig. 1d). During this long-term, low-dose treatment with CAM, the discrete ulceration of the terminal ileum was never revealed by follow-up total colonoscopy once or twice per year for 7 years (fig. 1e).