PMC7288206_01
Esophageal squamous papilloma in Case 1. Esophageal squamous cell papilloma is an exophytic growth with wart-like projections on conventional endoscopy. Its whitish color is a poor differentiator from other lesions.
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fig1
Biopsies were taken of the stomach mucosa and mid-esophageal mass (see Figure 1).
Esophageal squamous papilloma in Case 1. Lesion is diagnosed pathologically with hematoxylin and eosin stain demonstrating a fibrovascular core branching out from the lamina propria forming finger-like projections without invasion into the submucosa surrounded by marked neutrophil infiltration and covered by acanthotic squamous epithelium (H&E, x20).
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fig2
Esophageal biopsy demonstrated findings consistent with squamous papilloma (see Figures 2 and 3).
Esophageal squamous papilloma in Case 1. A fibrovascular core branching out from the lamina propria forming finger-like projections (yellow arrow) without invasion into the submucosa surrounded by marked neutrophil infiltration (red arrow) and covered by acanthotic squamous epithelium (black arrowhead) can be seen (H&E, x100).
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fig3
Esophageal biopsy demonstrated findings consistent with squamous papilloma (see Figures 2 and 3).
PMC7288206_02
Partially visible esophageal squamous papilloma in Case 2 demonstrating exophytic growth with wart-like projections.
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fig4
PMC7288206_03
Esophageal squamous papilloma in Case 3. Note is made of fibrovascular cores branching out from the lamina propria forming finger-like projections surrounded by marked neutrophil infiltration and covered by acanthotic squamous epithelium (H&E, x20).
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fig5
Esophageal biopsy demonstrated findings consistent with squamous papilloma (see Figures 5 and 6).
Esophageal squamous papilloma in Case 3. Several fibrovascular cores branching out from the lamina propria with finger-like projections can be seen without invasion into the submucosa. These are surrounded by marked neutrophil infiltration and covered by acanthotic squamous epithelium (H&E, x100).
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fig6
Esophageal biopsy demonstrated findings consistent with squamous papilloma (see Figures 5 and 6).