PMC3964433_01
Upper Endoscopic View of the Middle Esophagus Shows Pigmented Lesion of the Mucosa
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Conventional upper endoscopy showed black discoloration in the middle part of the esophagus (Figure 1).
A. Microscopic Section From the Surface Squamous Epithelium Shows Scattered Pigmented Cells Between the Keratinocytes. (H & E X400). B. Lamina Properia Shows Many Heavily Pigmented Cells. (H & E X250)
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Hematoxylin and Eosin (H & E) sections showed increased numbers of pigment-laden dendritic melanocytes and deposition of coarse brownish black pigment within the basal layer of the squamous epithelium and also in the lamina properia (Figure 2 A, B).
The Above Mentioned Cells Positive by Masson Fontana Stain. (Masson Fontana X250)
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These cells were positive by Masson Fontana (Figure 3).