PMC9997602_01
Changes in blood test reports during the use of cefoperazone/sulbactam (the left side of the arrow) and after withdrawal of it, replaced by meropenem (the right side of the arrow) [a-f]
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F1
After 1 month of anti-infective therapy, the infection improved, and the WBC and NE also decreased [Figure 1a and b]. Meanwhile, her RBC, HCT, and Hb continued to decrease [Figure 1d-f]. PLT showed a trend of fluctuation [Figure 1c]. WBC was on the rise [Figure 1a], and the patient still had intermittent fever at this time with pathogenic bacteria cultured in the bile. We gave her meropenem injection instead of cefoperazone/sulbactam to continue the anti-infective treatment.
Changes of serum indirect bilirubin (IBIL) during the use of cefoperazone/sulbactam (the left side of the arrow) and after withdrawal of it, replaced by meropenem (the right side of the arrow)
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F2
There was no significant change in LDH, and there was a delayed ascent in IBIL [Figure 2].