PMC8214874_01
CT scan demonstrating ill-defined low-attenuation masses within the superior pole and mid-region of the right kidney.
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In addition, abdominal and pelvic CT demonstrated newly developed renal masses, left adrenal mass, and pancreatic mass, also likely representing metastatic disease (Figure 1).
Low magnification image showing the tumor infiltrating the renal parenchyma (H&E, 40x); high magnification showing cytologic details of the tumor cells (H&E 200x).
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Immunohistochemical staining for anti-CK5/6 (A), anti-GATA3 (B), anti-CK20 (C), anti-PAX8 (D).
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Immunohistochemical studies showed the tumor cells to be diffusely and strongly positive for CK5/6 and negative for PAX8 and CK20 (Figure 3).