PMC4720495_01
Tumour staining with hematoxylin and eosin.
can-9-607fig1.jpg
PMC4720495_01_can-9-607fig1.jpg
figure1
The breast CNB yielded the diagnosis of invasive pleomorphic carcinoma (Figure 1) with positive hormonal receptors (oestrogens 100% and progesterone 80%, Ki67 70%, HER-2 positive (3+) (Figure 2), CK19 positive, E-cadherin negative (Figure 3), and P63 negative.
Positive tumour staining for HER-2 (3+).
can-9-607fig2.jpg
PMC4720495_01_can-9-607fig2.jpg
figure2
The breast CNB yielded the diagnosis of invasive pleomorphic carcinoma (Figure 1) with positive hormonal receptors (oestrogens 100% and progesterone 80%, Ki67 70%, HER-2 positive (3+) (Figure 2), CK19 positive, E-cadherin negative (Figure 3), and P63 negative.
Absence of E-cadherin staining observed.
can-9-607fig3.jpg
PMC4720495_01_can-9-607fig3.jpg
figure3
The breast CNB yielded the diagnosis of invasive pleomorphic carcinoma (Figure 1) with positive hormonal receptors (oestrogens 100% and progesterone 80%, Ki67 70%, HER-2 positive (3+) (Figure 2), CK19 positive, E-cadherin negative (Figure 3), and P63 negative.
Positive staining for synaptophysin in more than 50% of the tissue permits the diagnosis of a neuroendocrine tumour.
can-9-607fig4.jpg
PMC4720495_01_can-9-607fig4.jpg
figure4
The positivity of synaptophysin (Figure 4) suggested that the tumour was neuroendocrine in origin.