PMC7488878_01
Extramedullary hematopoiesis with megakaryocytes and sinusoidal capillarization adjacent to an area of fibroblastic proliferation (hematoxylin-eosin, 40x).
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A CT-guided liver core biopsy was performed on one of the liver lesions and showed megakaryocytes and sinusoidal capillarization adjacent to an area of fibroblastic proliferation (Figure 1).
Numerous atypical megakaryocytes along with fibroblastic proliferation and fibrosis/sclerosis (hematoxylin-eosin, 200x).
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The megakaryocytes were atypical and were identified along with intermingled areas of fibroblastic proliferation and fibrosclerosis (Figure 2).
Cytokeratin, immunohistochemical stain (100x).
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Keratin was positive only in hepatocytes (Figure 3) and Myosin staining highlighted smooth muscle and a few scattered cells (Figure 4).
Myosin, immunohistochemical stain (100x).
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Keratin was positive only in hepatocytes (Figure 3) and Myosin staining highlighted smooth muscle and a few scattered cells (Figure 4).
CD61, immunohistochemical stain (100x).
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CD61 stained megakaryocytes (Figure 5). CD163 stained numerous histiocytes.