PMC5286487_01
Macroscopic findings demonstrated a 2 cm polypoid blackish-pigmented tumor in the cervix (a). Multiple small blackish-pigmented tumors throughout the vaginal wall spreading to the lower third of the vagina (b).
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Gynecologic examination and colposcopic findings revealed a 2 cm polypoid blackish-pigmented tumor in the cervix, and multiple small blackish-pigmented lesions were found throughout the vaginal wall, spreading to the lower third of the vagina (Figure 1).
Surgical specimens showed a 2 cm polypoid blackish-pigmented tumor in the uterine cervix (a), and multiple small blackish-pigmented tumors throughout the vaginal wall (b).
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She underwent radical hysterectomy, bilateral salpingooophorectomy, pelvic lymphadenectomy, and total vaginectomy (Figure 2) without any major complications, and optimal surgery was achieved with no residual tumors.
Pathological findings of the cervix revealed spindle-shaped tumor cells showing intracytoplasmic melanin (a) and strong reactivity for melan-A (b). There were similar findings in the vagina (c, d). The invasion depth of the cervical tumor was deeper than that of the vaginal tumors. Magnification: (a) x400, (b) x400, (c) x40, (d) x100.
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Pathological examination of the cervix and vaginal wall demonstrated spindle-shaped tumor cells showing intracytoplasmic melanin and strong reactivity for melan-A (Figure 3).