PMC3325738_01
A) Non-contrast chest computed tomograohy scan showing left lower lobe ground-glass opacification; B) chest positron emission tomography - computed tomography image demonstrating FDG-avidity of left lower lobe opacity.
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F1
FDG-avid on positron emission tomography (Figure 1B). Flexible bronchoscopy with broncho-alveolar lavage of the left lateral basal segment was performed.
Transthoracic needle aspiration biopsy specimens from left lower lobe ground-glass opacity, original magnification x400, with hematoxylin-eosin (A) and cyclin D1 (B) stains depicting an atypical population of CD-20 positive B-cells coexpressing CD-5, blc-2, and cyclin D1.
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F2
Transthoracic fine needle aspiration of the lesion was ultimately performed and showed an atypical population of CD-20 positive B-cells (Figure 2A) coexpressing CD-5, blc-2, and cyclin D1 (Figure 2B) consistent with pulmonary mantle cell lymphoma.