PMC6374296_01
Low (A, 40X) and high (B, 100X) magnification pictures of appendiceal mucinous adenocarcinoma. H&E stained.
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F1
Postoperative pathology confirmed mucinous adenocarcinoma of the appendix T4NxM1, stage IV with peritoneal carcinomatosis (Figure 1).
Pelvic CT images before (A,B) vs. after (C,D) targeted therapy. (A,B) Prior to targeted therapy, images showed intraperitoneal multiple nodules, and a large number of peritoneal cavities filled up with mucus. (C,D) After targeted therapy using bevacizumab and oxaliplatin, image on the same sections showed significantly reduced peritoneal nodules and mucous cavities, suggesting stabilization of disease progression and partial response.
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F2
The patient failed to response to further systemic chemotherapy, and a large number of PPM (Figures 2A,B). Follow-up examination after treatment showed significant improvement of the patient's condition, and CT scan imaging results showed dramatic reduction of her peritoneal mucus (as shown in Figures 2C,D).