PMC9309724_01
CT scan of the patient before and after induction therapy showed the tumor response. CT, Computed tomography.
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Systemic evaluation including brain magnetic resonance imaging (MRI), whole-body bone scan, and chest contrast-enhanced computed tomography (CT) scan revealed a soft tissue mass on the upper lobe of the right lung (3.9 cm x 3.0 cm) and multiple enlarged lymph nodes in both supraclavicular fossa and mediastinum ( Figure 1 ). After six cycles of induction therapy, the patient achieved a partial response (PR) based on the Response Evaluation Criteria In Solid Tumors (RECIST) 1.1 ( Figure 1 ) and the driver gene mutation of the blood sample by NGS testing had no change ( Table 1 ).
Timeline of diagnosis and treatment in this case. PD-L1, Programmed cell death-ligand 1; TPS, Tumor Proportion Score; MRI, Magnetic resonance imaging; PTV, Planning target volume.
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The patient died in September 2021 ( Figure 2 ).