PMC7303452_01
PMC7303452_02
A: Chest radiography on admission showing cardiac enlargement and bilateral pleural effusion. B: Chest computed tomography showing bilateral pleural effusion and bilateral lung fibrosis. C: Chest computed tomography showing pericardial effusion and bilateral pleural effusion.
1349-7235-59-1315-g001.jpg
PMC7303452_02_1349-7235-59-1315-g001.jpg
g001
A chest X-ray showed cardiomegaly (Fig. 1A). Chest computed tomography (CT) showed pericardial effusion and pleural effusion (Fig. 1B, C).
Clinical course of the current case after admission.
1349-7235-59-1315-g002.jpg
PMC7303452_02_1349-7235-59-1315-g002.jpg
g002
The clinical course of this case after admission is shown in Fig. 2.
Histological findings of heart (A, B), brain (C, D), kidney (E), and lung (F). A: The black arrowheads indicate coronary arterial thrombi [Hematoxylin and Eosin (H&E) staining, 200x]. B: The black arrowheads indicate myocardial hemorrhaging (H&E staining, 40x). C: The black arrowheads indicate a microthrombus in the subcortex (H&E staining, 100x). D: The black arrowhead indicates a microthrombus, and the white arrowhead indicates microhemorrhaging in the midbrain (H&E staining, 40x). E: The black arrowheads indicate microthrombi in the glomerular capillaries (Elastica-Masson stain, 100x). F: Diffuse alveolar hemorrhaging based on interstitial fibrosis (Elastica-Masson stain, 100x).
1349-7235-59-1315-g003.jpg
PMC7303452_02_1349-7235-59-1315-g003.jpg
g003
An autopsy revealed coronary arterial thrombi (Fig. 3A), myocardial hemorrhaging (Fig. 3B), microthrombi and microhemorrhaging of the subcortex and midbrain (Fig. 3C, D), microthrombi in the glomerular capillaries (Fig. 3E), and diffuse alveolar hemorrhaging based on interstitial fibrosis of both lower lung fields (Fig. 3F).