PMC7498961_01
Whole body positron emission tomography showing patchy thoracolumbar marrow
uptake, with focal increased uptake in the left lateral aspect of the L2
vertebral body seen in the sagittal cut (A), frontal cut (B), and axial cut
(C).
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Following his first discharge from our facility, outpatient positron emission tomography (PET) was performed, which showed patchy thoracolumbar marrow uptake with increased focal uptake of the left lateral aspect of the L2 vertebral body (Figure 1).
(A) Low-power (200x magnification) hematoxylin and eosin (H&E) section
demonstrating intravascular involvement by B-cell lymphoma. (B) High-power
(600x magnification) H&E section showing atypical B-cells with open
chromatin and prominent nucleoli within intravascular space.
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He then underwent a vertebral body biopsy, which was highly suspicious for involvement of a B-cell neoplasm, prompting a repeat bone marrow biopsy, which showed a large B-cell lymphoma exclusively involving the vasculature and with low level (less than 1%) marrow involvement (Figure 2).