PMC8365508_01
Imaging and bronchoscopic findings of the patient.
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Chest radiography revealed a nodule in the left lower lung field (Fig. 1A), while computed tomography (CT) scan of the chest revealed a 14-mm heterogeneous round nodule with surrounding ground-glass opacity in the left lower lobe. (Fig. 1B and C). Bronchoscopic images revealed a blood clot found in the trachea (Fig. 1D). The lesion in the left lower lobe was approached with the aid of a radial endobronchial ultrasonography (R-EBUS) but the lesion was adjacent to the probe (Fig. 1E). The probe was eccentrically oriented to the lesion (Fig. 1F) and there was minimal bleeding.
Pathological findings of specimens from transbronchial cryobiopsy.
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Histologically, epithelioid cells with solid proliferation and a low nuclear to cytoplasmic ratio, and various papillary lesions covered by type II pneumocyte-like-cells (Fig. 2A) were observed. Hemosiderin-laden histiocytes (Fig. 2B) were present in the superficial layer; immunohistochemical staining revealed the histiocytes positive for thyroid transcription factor-1 (TTF-1) (Fig. 2C) and vimentin, and the type II pneumocyte-like-cells positive for cytokeratin 7 (Fig. 2D).