PMC3643361_01
Polygonal cells with abundant pale cytoplasm with anisonucleosis, increased nuclear cytoplasmic ratio, overlapping nuclei and irregular nuclear contours (Diff Quik stain, x400)
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F1
Polygonal cells with abundant pale cytoplasm exhibited anisonucleosis, increased nuclear cytoplasmic ratio, overlapping nuclei and irregular nuclear contours [Figure 1].
Hyaline stalks with overlying spindle cell with elongated oval nuclei and scant cytoplasm (Diff Quik stain, x200)
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F2
Spindle cells with elongated oval nuclei and scant cytoplasm surrounded metachromatic hyaline globules and hyaline stalks [Figures 2 and 3].
Metachromatic hyaline globules (Diff Quik stain, x400)
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F3
Spindle cells with elongated oval nuclei and scant cytoplasm surrounded metachromatic hyaline globules and hyaline stalks [Figures 2 and 3].
Cell block showing anastomosing papillary cores lined by plump endothelial cells and attenuated endothelial cells overlying hyalinized cores (H and E, x200)
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F4
Subsequent cell block showed characteristic features of IVPEH characterized by papillary cores lined by plump endothelial cells, adjacent to small delicate papillae [Figure 4].
Factor VIII immunostain outlined the endothelial cells in cell block sections (IHC, x200)
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F5
Immunohistochemical stains for factor VIII and CD34 performed on the cell block material outlined the endothelial cells [Figure 5].
Histological section of resected tumor showing numerous areas of endothelial ingrowths and delicate papillae with hyalinized cores covered by attenuated endothelial cells (H and E, x200)
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F6
The characteristic features of IVPEH with numerous areas of endothelial ingrowths and delicate papillae with hyalinized cores covered by attenuated endothelial cells as noted in cell block sections were seen [Figure 6].