PMC4310453_01
(a) Preoperative sagittal T2-weighted lumbar MRI demonstrated well-circumflanced, hypointense lesion anterior to L3 vertebrae. (b) Preoperative axial T2-weighted lumbar MRI demonstrated the well-circumferenced lesion with slightly hyperintense signal according to neural structures and hypointense signal according to CSF.
CRINM2015-708472.001.jpg
PMC4310453_01_CRINM2015-708472.001.jpg
fig1
This lesion was pushing intradural neural structures to the left side and anterolaterally (Figures 1(a) and 1(b)). The lesion was well-circumfluenced with homogenous contrast enhancement.
(a) Uniform spindle cells arranged in interlacing fascicles with deposition of scanty collagen among tumor cells (HE x400). (b) Scarce collagen network was demonstrated among tumor cells with Masson's trichrome stain (MTC, x200). (c) Scarce reticulin network was demonstrated between many tumor cells with Gomori reticulin (Gomori's reticulin, x400). (d) Strong and diffuse immunopositivity with vimentin (streptavidin biotinylated complement; vimentin x400).
CRINM2015-708472.002.jpg
PMC4310453_01_CRINM2015-708472.002.jpg
fig2
Histological examination revealed uniform spindle cells arranged in interlacing fascicles with deposition of scanty collagen between cells (Figure 2(a)). Masson's trichrome stain showed scarce collagen network between many tumor cells (Figure 2(b)). Scarce reticulin network was demonstrated between many tumor cells with Gomori reticulin (Figure 2(c)). Immunohistological findings revealed strong and diffuse immunopositivity with vimentin (Figure 2(d)), CD34, and bcl-2 (Figures 3(a) and 3(b)).
(a) Strong and diffuse immunopositivity with CD34 (streptavidin biotinylated complement; CD34, x400). (b) Diffuse immunopositivity with bcl-2 (streptavidin biotinylated complement; bcl-2, x400). (c) Ki-67 proliferation index was 5-8% (streptavidin biotinylated complement; MIB-1, x400). (d) Nuclear p53 oncoprotein was dispersing but mild in intensity (streptavidin biotinylated complement; p53 x400).
CRINM2015-708472.003.jpg
PMC4310453_01_CRINM2015-708472.003.jpg
fig3
Immunohistological findings revealed strong and diffuse immunopositivity with vimentin (Figure 2(d)), CD34, and bcl-2 (Figures 3(a) and 3(b)). Ki-67 proliferation index was 5-8% (Figure 3(c)) and nuclear p53 oncoprotein was randomly distributed but was mild in intensity (Figure 3(d)).