PMC6076956_01
Clinical features of prurigo pigmentosa. Patient 1 was noted to have symmetrically distributed erythematous papules and papulovesicules, admixed with postinflammatory and reticulated hyperpigmentation on the middle back, lumbosacral area, lateral chest wall (a), and the nape of the neck (b). In patient 2, there were erythematous papules with postinflammatory hyperpigmentation on the lateral chest wall, the back (c), and the central chest (d). Scattered excoriations were also noted.
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fig1
In addition, patient 1 had associated vesicles and minimal erosions (Figures 1(a) and 1(b)).
PMC6076956_02
Clinical features of prurigo pigmentosa. Patient 1 was noted to have symmetrically distributed erythematous papules and papulovesicules, admixed with postinflammatory and reticulated hyperpigmentation on the middle back, lumbosacral area, lateral chest wall (a), and the nape of the neck (b). In patient 2, there were erythematous papules with postinflammatory hyperpigmentation on the lateral chest wall, the back (c), and the central chest (d). Scattered excoriations were also noted.
CRIDM2018-9406797.001.jpg
PMC6076956_03_CRIDM2018-9406797.001.jpg
fig1
In addition, patient 1 had associated vesicles and minimal erosions (Figures 1(a) and 1(b)).
PMC6076956_03
Clinical features of prurigo pigmentosa. Patient 1 was noted to have symmetrically distributed erythematous papules and papulovesicules, admixed with postinflammatory and reticulated hyperpigmentation on the middle back, lumbosacral area, lateral chest wall (a), and the nape of the neck (b). In patient 2, there were erythematous papules with postinflammatory hyperpigmentation on the lateral chest wall, the back (c), and the central chest (d). Scattered excoriations were also noted.
CRIDM2018-9406797.001.jpg
PMC6076956_03_CRIDM2018-9406797.001.jpg
fig1
In addition, patient 1 had associated vesicles and minimal erosions (Figures 1(a) and 1(b)).
Histopathological features of prurigo pigmentosa. Biopsies taken showed evidence of mild hyperkeratosis, acanthosis, spongiosis, and mild superficial perivascular inflammatory cell infiltrate on low power in patient 1, patient 2, and patient 3 (a, c, and e, resp.), as well as dyskeratosis and hydropic degeneration of the basal cell layer, papillary dermal oedema, and superficial perivascular lymphoid cell infiltrate containing neutrophils and nuclear dust on high power. High power showed additional features of dyskeratotic hydropic degeneration of the basal cell layer, papillary dermal oedema, and superficial perivascular lymphoid cell infiltrate containing neutrophils and nuclear dust in patient 1, patient 2, and patient 3 (b, d, and f, resp.).
CRIDM2018-9406797.002.jpg
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fig2