PMC7656190_01
Chest x-ray: (a) posteroanterior and (b) lateral. Small calcified nodes were present in the inferior right hilum and subcarinal chain (indicated by the arrow). No suspicious pulmonary nodules nor infiltrates were identified.
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F1
Chest radiographs revealed small minimally calcified lymph nodes in the inferior right hilum and subcarinal chain (Fig. 1).
The 2.0x1.0 cm mildly erythematous thin plaque with a yellow crust.
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F2
One year later, the patient presented with recurrence of the lesion as a 2.0x1.0 cm thin, irritated, erythematous and crusted plaque (Fig. 2).
H&E stain of the second tissue biopsy revealed granulomatous inflammation and numerous yeast cells within macrophages, x400 (a) and x1000 (b) original magnifications. PAS (c) and GMS (d) stains of the tissue highlighted the presence of the yeast, x1000 original magnifications.
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F3
Repeat biopsy was performed and showed findings similar to those previously described; however, numerous yeast forms were noted in this specimen (Fig. 3a, b). The organisms were highlighted by periodic acid-Schiff (PAS) and Grocott-Gomori methenamine silver (GMS) stains (Fig. 3c, d).