PMC3081487_01
Photograph showing ulceroproliferative lesion over left gluteal region with chronic discharging sinus over right gluteal region
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On local examination, an oval ulceroproliferative lesion of about 10x7 cm was noted on left gluteal region near the natal cleft.[Figure 1] The growth was not fixed to underlying muscle and had everted edges.
Photomicrograph showing epidermal cyst with lumen filled with keratinous material. (H and E, x100)
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Histopathologically, multiple sections from tissue showed ulcerative lesion and deeper tissue with thick-walled epidermal cyst [Figure 2].
Photomicrograph showing cyst wall with areas of squamous cell carcinoma with foci of invasion. (H and E, x400)
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The cyst was lined by squamous epithelium at areas forming squamous hyperplasia, dysplasia; and invasive squamous cell carcinoma which was composed of neoplastic cells arranged in small sheets, clusters and masses [Figure 3].