PMC5553242_01
Histology shows diffuse infiltration of immature monotonous large hyperchromatic neoplastic cells with scanty cytoplasm (H and E, x400)
JRMS-22-83-g001.jpg
PMC5553242_01_JRMS-22-83-g001.jpg
F1
Immunohistochemistry shows positivity for leukocyte common antigen
JRMS-22-83-g002.jpg
PMC5553242_01_JRMS-22-83-g002.jpg
F2
Immunohistochemical studies consistently manifested the expression of leukocyte common antigen, BCL2, CD117, CD68 (focally), and Ki67 index about 60%, [Figures 2-6] but the expression of cytokeratin, placental alkaline phosphatase, CD10, CD3, CD20, CD3O, CD34, and ALK1 was negative and the diagnosis of granulocytic sarcoma was established.
Immunohistochemistry shows positivity for CD117
JRMS-22-83-g003.jpg
PMC5553242_01_JRMS-22-83-g003.jpg
F3
Immunohistochemical studies consistently manifested the expression of leukocyte common antigen, BCL2, CD117, CD68 (focally), and Ki67 index about 60%, [Figures 2-6] but the expression of cytokeratin, placental alkaline phosphatase, CD10, CD3, CD20, CD3O, CD34, and ALK1 was negative and the diagnosis of granulocytic sarcoma was established.
Immunohistochemistry shows positivity for BCL2
JRMS-22-83-g004.jpg
PMC5553242_01_JRMS-22-83-g004.jpg
F4
Immunohistochemical studies consistently manifested the expression of leukocyte common antigen, BCL2, CD117, CD68 (focally), and Ki67 index about 60%, [Figures 2-6] but the expression of cytokeratin, placental alkaline phosphatase, CD10, CD3, CD20, CD3O, CD34, and ALK1 was negative and the diagnosis of granulocytic sarcoma was established.
Ki67 index is about 60% of neoplastic cells (x400)
JRMS-22-83-g005.jpg
PMC5553242_01_JRMS-22-83-g005.jpg
F5
Immunohistochemical studies consistently manifested the expression of leukocyte common antigen, BCL2, CD117, CD68 (focally), and Ki67 index about 60%, [Figures 2-6] but the expression of cytokeratin, placental alkaline phosphatase, CD10, CD3, CD20, CD3O, CD34, and ALK1 was negative and the diagnosis of granulocytic sarcoma was established.
Ki67 index is about 60% of neoplastic cells (x400)
JRMS-22-83-g006.jpg
PMC5553242_01_JRMS-22-83-g006.jpg
F6
Immunohistochemical studies consistently manifested the expression of leukocyte common antigen, BCL2, CD117, CD68 (focally), and Ki67 index about 60%, [Figures 2-6] but the expression of cytokeratin, placental alkaline phosphatase, CD10, CD3, CD20, CD3O, CD34, and ALK1 was negative and the diagnosis of granulocytic sarcoma was established.