PMC3460706_01
(A) Slit lamp photograph of case 1 at presentation displaying fungal masses in the anterior chamber, representing a large Aspergillus infiltrate. (B) Gross examination of the globe in case 1 discloses a funnel-shaped retinal detachment, a vitreous cavity full of silicone oil, a closed anterior chamber with a dense cyclitic membrane, and a white fibrous plaque on the anterior and posterior surface of the iris. (C) Left image shows low magnification histopathology of the anterior segment of case 1, and is magnified on the right image.. Notes: On this image, examination of the ciliary body of case 1 displays septated hyphae consistent with Aspergillus. Cultures confirmed this organism. (Left, hematoxylin-eosin staining, original magnification x100; right, Gomori methamine silver staining, original magnification x400).
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f1-opth-6-1573
PMC3460706_02
(A) Slit lamp photograph of case 1 at presentation displaying fungal masses in the anterior chamber, representing a large Aspergillus infiltrate. (B) Gross examination of the globe in case 1 discloses a funnel-shaped retinal detachment, a vitreous cavity full of silicone oil, a closed anterior chamber with a dense cyclitic membrane, and a white fibrous plaque on the anterior and posterior surface of the iris. (C) Left image shows low magnification histopathology of the anterior segment of case 1, and is magnified on the right image.. Notes: On this image, examination of the ciliary body of case 1 displays septated hyphae consistent with Aspergillus. Cultures confirmed this organism. (Left, hematoxylin-eosin staining, original magnification x100; right, Gomori methamine silver staining, original magnification x400).
opth-6-1573f1.jpg
PMC3460706_02_opth-6-1573f1.jpg
f1-opth-6-1573
(A) Slit lamp photograph of case 2 at presentation showing corneal edema, and a complete hypopyon with dense fibrin within the anterior chamber. (B) Histopathology of case 2 displays a centrally gathered and detached retina with inflammatory material present within the anterior chamber and anterior vitreous. (Hematoxylin-eosin staining, original magnification x40). (C) Histopathology on the left indicating area of collection in the anterior chamber, highlighted in the image on the right showing the contents of the anterior chamber displaying septated fungal hyphae consistent with Aspergillus.. Notes: Cultures confirmed this organism. (Left, hematoxylin-eosin staining, original magnification x100; right, Gomori methamine silver staining, original magnification x400).
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One month later, the patient was referred to Bascom Palmer Eye Institute with light perception vision, and examination was remarkable for complete hypopyon, corneal edema, a white plaque over the iris, and moderately dense vitreous membranes by ultrasound (Figure 2A).