PMC4864901_01
Low magnification showing a diffuse infiltration of atypical lymphoid cells in the thyroid gland (haematoxylin & eosin stain, x50)
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Fig1
A biopsy of the cervical mass was carried out and the histological examination showed diffuse infiltration of the thyroid gland by a monotonous population of atypical intermediate-sized lymphoid cells (Fig. 1).
Immunohistochemical staining revealed the expression of CD20 (a) and CD10 (b) by the neoplastic cells. Keratin highlights the lymphoepithelial lesions (c). Ki-67 immunostaining showed a high proliferation index (d)
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Fig3
CD3 and CD5 stained the background T cells (Fig. 3).
CT showing a large heterogeneous mass of the thyroid gland
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Fig4