PMC535804_01
CT shows a retroperitoneal bulky mass. (B) The clinical course from the treatment of EGGCT to that of seminoma.
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F1
CT showed a retroperitoneal tumor (Figure 1), and a transabdominal needle biopsy was carried out. No recurrence has been seen since the surgery (Figure 1B).
Photomicrograph of extragonadal non-seminomatous germ cell tumor with a focus of yolk sac tumor. A: H&E section shows characteristic structures suggestive of Schiller-Duval bodies (x200). B: Alpha-fetoprotein immunohistochemical stain is focally positive at the above area (x400).
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F2
Microscopically, the tumor was composed of a yolk sac tumor (Figure 2A,2B).
Photomicrograph of classic seminoma of the testis. A: H&E section shows compact nests of large tumor cells are separated by thin fibrous septa infiltrated by lymphocytes. B: Intratubular germ cell neoplasia in H&E section (x100). A row of atypical germ cells with clear cytoplasm is seen against a thickened basement membrane. No spermatogenesis is occurring in this tubule (x200).
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F3
Pathology showed the resected tumor was a seminoma with CIS (Figure 3A,3B).