PMC9491343_01
Timeline of progression of illness and workup.
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F1
The timeline of her illness and workup is summarized in Figure 1. Supplementary Figure 1 performed shows that the isolate from our patient was serogroup A.
Imaging findings of chest wall mass and rib osteomyelitis. (A) Chest X-ray shows destruction of a rib. (B) Left chest wall mass (axial image). (C) Left chest wall mass (coronal view). Green arrow indicates the level of 7th rib fracture and mass.
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F2
A chest X-ray obtained at that time showed a lytic lesion of the left 7th rib with no acute pulmonary process (Figure 2A). CT of chest and abdomen showed left chest wall mass and destruction of 7th rib (Figures 2B,C).
Grocott's Methenamine Silver (GMS) stain of aspirate showing yeast forms. Objective: 200x.
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F3
AFB smears were negative but Grocott's Methenamine Silver (GMS) stain showed "yeast forms" (Figure 3). Aerobic bacterial cultures and fungal cultures grew C. neoformans.