PMC2629966_01
Chest X-ray film. A. Before transplantation, showing bilateral hyperinflation. Note also the increased interstitial marking and scarring in the basilar portions. B. Two months after left lung transplantation, showing well-inflated left lung.
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Chest X-ray film (Figure 1) demonstrated bullous emphysema and fibrotic changes, predominantly in the lower lobes.
CT scan of the chest demonstrating severe emphysematous changes with bullous formation and scarring.
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High-resolution CT of the chest (Figure 2) was consistent with emphysema, with marked hyperinflation of both lower lobes.
Pathologic study of the extracted lung. A. Note focal interstitial lymphocytic infiltrates (lower-left field) and giant foreign cells (arrows) with evidence of foreign material in the cytoplasm (hematoxylineosin; magnification x 200). B. Polarized particles in the interstitium and cytoplasm of the giant cells can be seen (magnification x 100).
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On microscopic examination (Figure 3), lymphocytic foci, congestion, and multinuclear giant foreign body cells with a foreign substance in their cytoplasm were seen.