PMC4314889_01
Erythematous nodules over leg
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F1
Examination revealed multiple tender, erythematous nodules over the anterior aspect of both lower legs and knees [Figure 1].
Boggy erythematous plaque over dorsum of the hand, with sutures at site of skin biopsy in the center
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F2
There was a large, erythematous, boggy, tender plaque on the dorsum of the right hand extending over to the dorsum of right index finger [Figure 2].
Targetoid erythematous nodule on the radial aspect of finger
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F3
There were large bullous and pustular lesions on an erythematous base over the radial aspect of right index finger [Figure 3].
Histopathology of a skin biopsy showing dermal edema and a dense neutrophilic infiltrate in the dermis (H and E, x40)
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F4
Few inflammatory cells were seen infiltrating the vessel wall; however, there was no extravasation of erythrocytes [Figures 4 and 5].
Section from the skin showing dense neutrophilic infiltrate (vertical arrow), along with vasculitis (horizontal arrow) (H and E, x100)
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F5
Few inflammatory cells were seen infiltrating the vessel wall; however, there was no extravasation of erythrocytes [Figures 4 and 5].