PMC8684417_01
Axial (A) and sagittal (B) CT scans of the whole abdomen included the pelvis with IV contrast injection demonstrated a large heterogenous enhancing mass, 5.3x6.2 cm in size with internal calcification in the urinary bladder.
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CT abdomen was done and revealed a large heterogeneous enhancing mass 5.3x6.2 cm in size with internal calcification in the urinary bladder (Figure 1).
The histological appearance of the urinary bladder melanoma tissue was composed of solid nests and groups of atypical, poorly differentiated, highly mitotically active cells with prominent nucleoli: HE x10 (A); HE x100 (B); HE x400 (C); immunohistochemistry indicating positive reaction to HMB-45 (x100) (D); Melan-A(x100) (E) and S-100 (x100) (F).
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Hematoxylin and eosin (H&E) staining was performed on tissue sections and S100 (+), HMB-45 (+), and Melan-A (+) were detected by immunohistochemistry (Figure 2).
Axial (A) and coronal (B) CT scan of the abdomen/pelvis with IV contrast injection, demonstrated a new left cardiophrenic lymph node enlargement.
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After a postoperative period of one year, a computerized tomography scan showed new cardiophrenic lymph node enlargement without local recurrence (Figure 3).