PMC4899637_01
a A well-demarcated nodule on the retroauricular skin, 20 x 20 mm in size. b Magnetic resonance imaging revealed a subcutaneous nodule located adjacent to the periosteum. c, d Proliferation of fibroblastic and histiocytic cells showing storiform-type whorling and a plexiform pattern. Original magnification: x100 (c), x400 (d).
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F1
On her initial visit, physical examination revealed a well-demarcated nodule on her retroauricular skin, 20 x 20 mm in size (fig. 1a). Magnetic resonance imaging revealed a subcutaneous nodule located adjacent to the periosteum (fig. 1b). The histopathological findings revealed proliferation of fibroblastic and histiocytic cells showing storiform-type whorling and a plexiform pattern (fig. 1c, d).
Paraffin-embedded tissue samples were deparaffinized and stained with anti-POSTN antibody (a), anti-CD163 antibody (b) and anti-CD206 antibody (c). The sections were developed with liquid permanent red. Original magnification: x200.
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F2
A dense deposition of POSTN was detected throughout the stromal areas of the tumor (fig. 2a). In addition, CD163+CD206- tumor-associated macrophages (TAMs) were densely infiltrated in the same areas of POSTN (fig. 2b, c).