PMC6612373_01
Biopsies of the ileal mucosa appearing normal structurally and cellularly. The submucosa is occupied by a Peyer's patch (asterisk). Hematoxylin and eosin original magnification, 40x.
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fig1
The submucosa was also sampled, encompassing few Peyer's patches (Figure 1).
Peyer's patch at higher magnification (hematoxylin and eosin 200x) contains several scattered pink-coloured, foamy macrophages.
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fig2
A periodic acid-Schiff (PAS, 200x) special stain displays the PAS-positivity of the macrophages.
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fig3
Amplification plot from the ileal sample concerned during the real-time PCR showing the amplification curve of specific T. whipplei DNA to 230 copies/ml.
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fig4
DNA (Figure 4). Diagnosis of WD was therefore established.