PMC4846041_01
Potential drug-gene and drug-drug interactions in the Case #1.. Notes: S: substrate; +: inducer; -: inhibitor; yellow background: mutant allele.. Abbreviation: Hctz, hydrochlorothiazide.
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PMC4846041_01_pgpm-9-031Fig2.jpg
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Figure 2 summarizes potential drug-gene and drug-drug interactions based on CYP450 metabolism found in the Case #1.
PMC4846041_02
Potential drug-gene and drug-drug interactions in the Case #2.. Notes: S: substrate; +: inducer; -: inhibitor; yellow background: mutant allele.
pgpm-9-031Fig3.jpg
PMC4846041_02_pgpm-9-031Fig3.jpg
f3-pgpm-9-031
Figure 3 provides a summary of potential drug-gene and drug-drug interactions related to CYP450 metabolism that were identified in the Case #2.
PMC4846041_03
Potential drug-gene and drug-drug interactions in the Case #3.. Notes: S: substrate; +: inducer; -: inhibitor.
pgpm-9-031Fig4.jpg
PMC4846041_03_pgpm-9-031Fig4.jpg
f4-pgpm-9-031
A summary of potential CYP450-based interactions is presented in Figure 4.