PMC8131089_01
Abdominal CECT showed a right renal mass (red arrow) with heterogeneous enhancement in the arterial phase (A) and washout in the venous (B) and delayed (C) phases.
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Contrast-enhanced computed tomography (CECT) of the abdomen (Figure 1) confirmed a right renal mass of 4.9x4.3x3.1 cm, which had arterial enhancement and washout in the portal and delayed phases.
Histological examination of the right renal lesion showed clear-cell RCC.
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Postoperative histologic examination confirmed clear-cell RCC (Figure 2).
Contrast-enhanced CT of the patient 2 months after right nephrectomy showed a lobulated, hypodense mass (red arrow) in the left lobe of the liver on pre-contrast scan (A) that was enhanced in the arterial phase (B) with equivocal washout in the portal (C) and delayed phases (D), suggesting HCC or metastasis from RCC.
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Contrast-enhanced MRI showed a left liver mass (red arrow) with arterial enhancement (A), equivocal washout in the venous (B) and 3-minute delayed phases (C), and a clear capsule in the 15-minute delayed phase (D).
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Histology of the liver lesions suggesting HCC.
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A percutaneous biopsy was performed, and histologic evaluation suggested well-differentiated HCC (Figure 5).
Immunohistochemistry of RCC. (A) HSA (-) (X100), (B) CK7 (-), (C) CK20 (-), (D) AE1/3 (+), (E) Vimentin (+), (F) CD10 (+).
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Immunohistochemistry confirmed the renal and hepatic lesions to be RCC and HCC, respectively (Figures 6 and 7).
Immunohistochemistry of HCC. (A) HSA (+) (X400), (B) CK7 (-), (C) CK20 (-), (D) AE1/3 (+), (E) Vimentin (-), (F) CD10 (-).
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Immunohistochemistry confirmed the renal and hepatic lesions to be RCC and HCC, respectively (Figures 6 and 7).