PMC5808448_01
a Optical coherent tomography image of the macula, showing retinal thickening, cystoid intraretinal spaces, and small subretinal fluid pockets. b Electroretinogram of the right eye shows both dark adopted maximal combined response and light adopted 30 Hz flicker response shows undetectable electroretinogram response. c Fundus photograph showing macular exudates, dilated veins and retinal hemorrhages. d Fluorescein angiography shows vascular staining and leakage and hypofluorescence due to ischemia
40942_2018_110_Fig1_HTML.jpg
PMC5808448_01_40942_2018_110_Fig1_HTML.jpg
Fig1
Fundus photograph, fluorescein angiography, optical coherent tomography (OCT) and electroretinography were requested (Fig. 1).
a Fundus photograph showing patchy intraretinal hemorrhages 20 days after vitrectomy. b Slit photograph showing mild corneal edema and mild patchy iris atrophy. c Ciliary body detachment and cleft and atrophy in UBM scan. d OCT scan shows small pockets of subretinal fluid. Retina showed atrophic changes in temporal retina and also reduce in retinal thickness. Edema was reduced 22 days after MMC injection. e Two months later, retina became atrophic and all layers became intertwined. Subretinal fluid was remained. f Iris atrophy progressed and pigment dispersed all over in the anterior chamber over the lens, iris and endothelium
40942_2018_110_Fig2_HTML.jpg
PMC5808448_01_40942_2018_110_Fig2_HTML.jpg
Fig2
In temporal to macula, retinal thickness was reduced and atrophy was initiated (Fig. 2a-d) After 2 months, visual acuity declined to poor light perception. In OCT, atrophy with all layers became intertwined and indistinguishable (Fig. 2e-f).
Slit lamp photograph of the patient showing mature cataract, mild corneal edema and diffuse spongy iris atrophy, one year after intravitreal MMC injection
40942_2018_110_Fig3_HTML.jpg
PMC5808448_01_40942_2018_110_Fig3_HTML.jpg
Fig3
Patient had mature cataract, diffuse iris atrophy, mid dilated iris and mild corneal edema (Fig. 3).