PMC9236464_01
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
PMC9236464_02
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
PMC9236464_03
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
PMC9236464_04
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
PMC9236464_05
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
PMC9236464_06
Slit lamp photographs of the perforated cornea in the 6 patients. Slit lamp photographs (A-F) show the corneal perforations in cases 1-6, respectively. All perforations occurred in the right eye. Red arrows indicate the area of corneal perforation. (A) Prior perforated area central to the inferonasal cornea with opacification and neovascularization are shown. A new perforation is observed temporal to that opacification, resulting in flattening of the anterior chamber. (B) Peripheral corneal thinning is apparent in the temporal to superior area with oval perforation in the superior area where the iris is incarcerated. The Anterior chamber is severely inflamed, with flare and severe hyperemia. (C) A small corneal perforation is observed slightly inferonasal to the corneal center. Flattening of the anterior chamber and severe hyperemia are also evident. (D) Peripheral corneal thinning in the inferonasal to temporal area is evident. A small corneal perforation is observed in the inferonasal area. (E) Inferonasal opacification of the cornea and neovascularization due to prior corneal perforation are shown. A perforation with iris fitting is apparent in the same area. (F) An oval perforation is apparent in the superior peripheral cornea. Although therapeutic SCL is applied and iris fitting has occurred, the anterior chamber is very shallow.
IMCRJ-15-313-g0001.jpg
PMC9236464_06_IMCRJ-15-313-g0001.jpg
f0001
At the time of the initial visit to our department, peripheral corneal perforation in the supranasal area was observed in the right eye, and the anterior chamber had flattened despite wearing the therapeutic SCL (Figure 1F).
The cornea of the other eye and lacrimal disease in the perforated eye. (A and B) Slit lamp photographs of the left eye in case 6 at the time of initial examination. Although no peripheral thinning or perforation of the cornea is evident, severe SPK is observed with fluorescent staining, indicating the presence of dry eye. (C) Slit lamp photograph of the right eye in case 6 on hospital day 13. Backflow of purulent discharge from the lacrimal duct is evident. (D) Intraoperative photograph of the right eye in case 6 on hospital day 15. Percutaneous dacryocystectomy (white dotted circle) and closure of the lacrimal puncta and lacrimal canaliculi are performed. Intraoperatively, a large lacrimal concretion (red dotted circle) is detected in the lacrimal sac and extracted. The concretion consists of MSSA and suspected fungus.
IMCRJ-15-313-g0002.jpg
PMC9236464_06_IMCRJ-15-313-g0002.jpg
f0002
In the left eye, no thinning or perforation of the peripheral cornea was observed (Figure 2A). SPK (Figure 2B). She was directly admitted the same day. Eleven days after LKP, reflux of purulent discharge from the lacrimal duct of the right eye was observed (Figure 2C). Dacryocystectomy and removal of the lacrimal concretion were then performed (Figure 2D), and the lacrimal punctum and canaliculi were closed by coagulation.