PMC3230581_01
Clinical photographs taken at maximum frown. (A) Patient prior to injection with incobotulinumtoxinA on December 24, 2009, after developing nonresponsiveness to preparations containing botulinum toxin complex. (B) Patient following injection with incobotulinumtoxinA on January 19, 2010, after the patient developed nonresponsiveness to preparations containing botulinum toxin complex. (C) Patient on February 25, 2010, about 1 month after the final botulinum toxin type A injection on January 19, 2010.
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The clinical photograph taken approximately 1 month after the final injection shows no remaining effect of neurotoxin (Figure 1C).