PMC8695900_01
The pulmonary lesions and lymph node metastases before and after the PD-L1 treatment. (A1, A2) Right lower pulmonary lesions and swollen lymph nodes were revealed in the CT images before starting the chemotherapy in May 2018. (B1, B2) Partial response of the lesions in the right lower lobe and swollen lymph nodes was shown after 6 cycles of chemotherapy and atezolizumab treatment in August 2018; (C1, C2) the lesions showed continuous partial response after 36 cycles of pemetrexed and atezolizumab; (D1, D2) the lesions indicated a decreased size in March 2021.
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Chest computed tomography (CT) revealed the tumor shadow in the right lower lobe of the lung, and it also demonstrated multiple swollen lymph nodes in the mediastinum ( Figure 1 ). 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET/CT) showed multiple 18F-fluorodeoxyglucose (18F-FDG) uptake in the right abdominal muscle, L4, and right iliac bone.
Longitudinal changes in PLT count or HGB over time. PLT, platelet; HGB, hemoglobin; MMF, mycophenolate mofetil; IVIG, intravenous immunoglobulin; TPO, thrombopoietin.
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Seven days later, his platelet counts started to increase and reach the normal range (100 to 300x103/ul) by 1 week ( Figure 2 ).