PMC3522514_01
Clinical appearance of the left inframammary giant cell tumor. Picture shows the left inframammary mass just prior to surgical resection (after prepping with betadine solution) in frontal (a) and lateral (b) view.
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Clinically, the lump was approximately 20.0 x 15.0 cm, hard in consistency, mildly tender, and located anteriorly below the left inframammary fold (Figure 1).
Giant cell tumor on CT scan of the chest. Computed tomography of the chest showing a large soft tissue mass arising anteriorly from the 7th rib, causing cortical destruction.
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Computed tomography of the chest (Figure 2) showed a tumor arising from the 7th rib anteriorly with marginal sclerosis, cortical destruction, and a soft tissue mass.
Gross specimen after surgical resection. Specimen showing giant cell tumor measuring 28.0 x 24.0 cm with an excised portion of the 7th rib.
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Histopathology reported a large lobular mass enclosing the rib and measuring 28.0 x 24.0 cm (Figure 3).
Histopathology of giant cell tumor. Microscopic examination with hematoxylin and eosin staining showing large number of multinucleate giant cells scattered over parenchyma with spindle-shaped mononuclear stromal cells (magnification x100).
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Microscopic examination revealed a large number of multinucleate giant cells scattered over the parenchyma (Figure 4).