PMC5587934_01
Clinicomorphological appearance of a giant conjunctival nevus (a). Nasal (b) and superonasal (c) parts of the lesion.
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fig1
On slit-lamp examination, a large conjunctival lesion with variegate pigmentation and indistinct margins was detected on the superonasal part of the bulbar conjunctiva of the left eye (Figure 1).
Results of anterior segment optical coherence tomography of conjunctival nevus. B scan images (a, b) show distinct posterior borders of various parts of the lesion with variegate degree of posterior shadowing and with numerous intralesional cystic lesion (b); C scans (c-e) can detect intralesional cysts (c) and intralesional vessels (d, e).
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fig2
Variegate severity of posterior shadowing and multiple intralesional cysts were detected on B scans, whereas C scans revealed the presence of intralesional cysts and intratumoral vascularity (Figure 2).
Histological examination revealed nevus cell nests with vertical maturation tendency and junctional activity in the epithelial-stromal border of the conjunctiva. Multiple cysts and intratumoral vessels could also be detected (magnification: (a) 10x, (b) 20x).
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fig3
The found histopathological signs were characteristic for compound type conjunctival nevus (Figure 3).