PMC5582400_01
Evanescent flushing on a The chest, b The back, c The hand, d The leg
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Fig1
Nine minutes after the ingestion he presented an evanescent erythematous rash on the face, trunk and extremities (Fig. 1), which lasted 12 min and resolved spontaneously.
Abdominal CT-scan showing liver metastasis
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Fig2
The CT scan showed thickening of the distal ileum and multiple lesions on both hepatic lobules (Fig. 2).
Colonoscopy with primary suspected tumor
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Fig3
To further evaluate these lesions, a colonoscopy was done which revealed (Fig. 3) a prominent ileocecal valve with a mammillated and eroded lesion.
Ileocecal valve mucosa biopsy showing a grade 2, well-differentiated NET a Hematoxylin and eosin (H&E) staining b Intense reactivity to chromogranin staining c KI 67 staining determined a 1% proliferation cellular index
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Fig4
The hepatic and intestinal biopsies identified a well-differentiated grade 2 primary NET (Fig. 4) of the ileocecal valve with hepatic metastasis.