PMC7330058_01
Hyperintense lesion with perifocal edema left occipital in fluid-suppressed T2 MRI technique (Fluid-attenuated inversion recovery (FLAIR) sequence).
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F1
Furthermore the patient displayed a decreased frequency of regulatory T cells (Treg) which also indicated a dysfunctional phenotype with low expression of CTLA4 (cytotoxic T-lymphocyte-associated Protein 4) as well as FOXP3 (Supplemental Figure 1). The largest lesion was located in the left posterior lobe with a diameter of 4.4 cm (Figure 1).
Hyperintense lesions in medulla oblongata and in cervical and upper thoracic spinal cord in contrast enhanced, fat suppressed T1 MRI technique.
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F2
Th2 segment (Figure 2). The clinical examination was inconspicuous, with no evidence of neurological symptoms.