PMC7200444_01
CT scan of the abdomen shows a well-defined enhancing mass.
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The Contrast enhanced computed tomography (CT) of the abdomen and pelvis showed a homogenous enhancing mass lesion in the retroperitoneum, with lobulated contours measuring 26 x 88 x 150 mm, massively calcified with significant collateral venous circulation (Fig. 1).
Macroscopic view of the specimen after resection.
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The retroperitoneal mass was widely dissected and completely excised along with its capsule, carefully and without complications (Fig. 2).
Histological examination: Castleman's disease of hyaline vascular type.. (a) Lymphoid tumor in soft tissue (adipose tissue visible at the level of the cartridge image). (HE, Low magnification).. (b) Atrophic follicles of the Castleman type vascular hyaline. (HE, medium magnification).. (c) Presence of ossification foci within the lesion. (HE, medium magnification).
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The microscopic examination revealed an enlarged lymphnode composed of multiple follicles of various sizes with involuted germinal centers (Fig. 3).
The immunohistochemical staining revealing positive findings of CD3 and CD20.
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The immunohistochemical study revealed CD20 (+, follicles), CD3 (+, parafollicles) and Bc12 (+, follicles) (Fig. 4).