PMC6689908_01
Preoperative sagittal MRI of the thoracic spine with contrast; significant for enhancing mass measuring 60 mm craniocaudal span.
10.1177_2324709619868255-fig1.jpg
PMC6689908_01_10.1177_2324709619868255-fig1.jpg
fig1-2324709619868255
Magnetic resonance imaging (MRI) of the thoracic spine revealed a 60 mm enhancing intramedullary expansile mass of the lower thoracic spinal cord extending from T10-T11 down to the upper portion of L1 with a width of 10 mm x 9 mm transversely at the level of T12 (Figures 1 and 2).
Preoperative sagittal MRI of the thoracic spine without contrast; significant for spinal cord mass at the level of T10-T12.
10.1177_2324709619868255-fig2.jpg
PMC6689908_01_10.1177_2324709619868255-fig2.jpg
fig2-2324709619868255
Magnetic resonance imaging (MRI) of the thoracic spine revealed a 60 mm enhancing intramedullary expansile mass of the lower thoracic spinal cord extending from T10-T11 down to the upper portion of L1 with a width of 10 mm x 9 mm transversely at the level of T12 (Figures 1 and 2).
Neoplastic cells with vascular proliferation and focal necrosis on hematoxylin and eosin stains (100x).
10.1177_2324709619868255-fig3.jpg
PMC6689908_01_10.1177_2324709619868255-fig3.jpg
fig3-2324709619868255
Microscopic examination of the biopsied intramedullary mass was significant for neoplastic cells with vascular proliferation and focal necrosis on hematoxylin and eosin stains (Figures 3 and 4), immunohistochemical staining for isocitrate dehydrogenase-1 (IDH1) was negative (Figure 5), and immunohistochemical staining for glial fibrillary acidic protein was positive (Figure 6).
Neoplastic cells with focal necrosis on hematoxylin and eosin stains (200x).
10.1177_2324709619868255-fig4.jpg
PMC6689908_01_10.1177_2324709619868255-fig4.jpg
fig4-2324709619868255
Microscopic examination of the biopsied intramedullary mass was significant for neoplastic cells with vascular proliferation and focal necrosis on hematoxylin and eosin stains (Figures 3 and 4), immunohistochemical staining for isocitrate dehydrogenase-1 (IDH1) was negative (Figure 5), and immunohistochemical staining for glial fibrillary acidic protein was positive (Figure 6).
Negative immunohistochemical staining for isocitrate dehydrogenase-1 (200x).
10.1177_2324709619868255-fig5.jpg
PMC6689908_01_10.1177_2324709619868255-fig5.jpg
fig5-2324709619868255
Microscopic examination of the biopsied intramedullary mass was significant for neoplastic cells with vascular proliferation and focal necrosis on hematoxylin and eosin stains (Figures 3 and 4), immunohistochemical staining for isocitrate dehydrogenase-1 (IDH1) was negative (Figure 5), and immunohistochemical staining for glial fibrillary acidic protein was positive (Figure 6).
Positive immunohistochemical staining for glial fibrillary acidic protein (100x).
10.1177_2324709619868255-fig6.jpg
PMC6689908_01_10.1177_2324709619868255-fig6.jpg
fig6-2324709619868255
Microscopic examination of the biopsied intramedullary mass was significant for neoplastic cells with vascular proliferation and focal necrosis on hematoxylin and eosin stains (Figures 3 and 4), immunohistochemical staining for isocitrate dehydrogenase-1 (IDH1) was negative (Figure 5), and immunohistochemical staining for glial fibrillary acidic protein was positive (Figure 6).
Postoperative MRI of the thoracic spine with contrast, postoperative day 1 of T9-T12 and L1 laminectomy with debulking of intramedullary spinal cord GBM. In this image, the residual tumor measures 30 mm in craniocaudal span.
10.1177_2324709619868255-fig7.jpg
PMC6689908_01_10.1177_2324709619868255-fig7.jpg
fig7-2324709619868255
Compared with previous imaging, there was a reduction of the primary GBM of 60 mm reduced to 30 mm in craniocaudal span at the level of T12 with no abnormal spinal fluid collection (Figures 7 and 8).
Postoperative MRI of the thoracic spine without contrast, postoperative day 1 of T9-T12 and L1 laminectomy with debulking of intramedullary spinal cord GBM.
10.1177_2324709619868255-fig8.jpg
PMC6689908_01_10.1177_2324709619868255-fig8.jpg
fig8-2324709619868255
Compared with previous imaging, there was a reduction of the primary GBM of 60 mm reduced to 30 mm in craniocaudal span at the level of T12 with no abnormal spinal fluid collection (Figures 7 and 8).