PMC3096646_01
Ophthalmological findings from a patient with paraneoplastic retinopathy (PR) associated with lung cancer.. (A) Threshold of static visual field (Humphrey, 30-2 program) plotted on a gray scale showing severely decreased sensitivities within the central 30 degrees of the visual field. (B) Fundus photographs of the patient showing a nearly normal fundus. (C) Fluorescein angiograms showing periphlebitis of the retinal vessels (arrows). (D) Spectral-domain optical coherence tomographic (SD-OCT) image of a 9 mm horizontal scan of the retina of our patient. The retinal structure in each retinal layer is normal.
pone.0019911.g001.jpg
PMC3096646_01_pone.0019911.g001.jpg
pone-0019911-g001
Humphrey static perimetry revealed a severe decrease in sensitivity within the central 30 degrees of the visual field in both eyes (Fig. 1A). Ophthalmoscopy showed a nearly normal fundus appearance except for slight hypopigmentation at the macula of the left eye, which may be due to age-related changes in the retinal pigment epithelium (Fig. 1B), but fluorescein angiography demonstrated periphlebitis of the retinal vessels (arrows, Fig. 1C). Spectral-domain optical coherence tomography (SD-OCT) showed that the morphology of the retina was normal in both eyes (Fig. 1D).