PMC7734128_01
MRI characteristics of Rosai-Dorfman disease involving sellar region. (A) Coronal and (B) sagittal T1-weighted magnetic resonance images. (C) coronal and (D) sagittal contrast-enhanced magnetic resonance images reveal thickened pituitary stalk with obvious homogenous enhancement (red arrow).
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F1
Contrast-enhanced brain MRI showed that the pituitary stalk was thickened with obvious homogenous enhancement and the high signal of posterior pituitary was disappeared in T1-weighted images (Figure 1).
Histological features of Rosai-Dorfman disease involving sellar region. (A) H-E staining of specimen reveals the large-size histiocyte with the typically foamy eosinophilic cytoplasm, original magnification x40 (black arrow). (B) Positive immunohistochemical staining for S-100, original magnification x100.
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F2
The diagnosis of Rosai-Dorfman disease was therefore yielded (Figure 2).
Timeline of the case presentation.
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F3
No abnormal lesions were found in head, neck, thorax, abdomen, and pelvis (Figure 3).