PMC3420702_01
Spindle-shaped bizarre tumor cells along with pleomorphic tumor giant cells and osteoclastic giant cells (H&E, 100x).
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fig1
Histology revealed fragments of gallbladder tissue displaying infiltrating tumor composed mainly of spindle-shaped pleomorphic cells with occasional bizarre giant cells (Figure 1).
High power view showing bizarre spindle-shaped tumor cells along with osteoclastic giant cells (H&E, 400x).
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fig2
Dispersed osteoclastic giant cells were seen throughout the tumor tissue (Figure 2).
Focal chondrosarcomatous area amidst undifferentiated carcinoma (H&E, 400x).
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fig3
Focal area showed chondrosarcoma (Figure 3).
Spindle-shaped tumor cells showing cytoplasmic positivity for cytokeratin (IHC for cytokeratin, 200x).
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fig4
On immunohistochemistry, majority of the spindle-shaped tumor cells and bizarre giant cells were positive for cytokeratin (Figure 4) with C-11, and 1 : 100 dilution (manufacturer:Biogenic) antibody was used.