PMC4971312_01
(a) Intraoral photograph showing well-circumscribed round 1.0 cm x 1.0 cm nodule over dorsum of tongue near left lateral border. (b) Peroperative photograph showing well-circumscribed tumor separated from the surroundings through blunt dissection. (c) Gross specimen appearing well-circumscribed, yellowish white, and oval and measuring 10.0 mm x 5.0 mm x 5.0 mm. (d) Cut surface of the excised tumor appearing homogenous, white, and firm without haemorrhage or necrosis.
CRID2016-3630153.001.jpg
PMC4971312_01_CRID2016-3630153.001.jpg
fig1
The overlying mucosa was nonulcerated and without any vascular prominence (Figure 1(a)). A vertical incision was given to expose the tumor mass from the overlying mucosa and it was gradually separated from the surroundings through blunt dissection (Figure 1(b)). The gross specimen was well-circumscribed, yellowish white, and oval shaped and measured 10.0 mm x 5.0 mm x 5.0 mm in dimension (Figure 1(c)). Cut surface was homogenous, white, firm, and without any evidence of haemorrhage or necrosis (Figure 1(d)).
(a) Low power photomicrograph (H&E, 10x) showing fibrous capsule, surrounding the tumor mass. (b) High power photomicrograph (H&E, 40x) showing tumor mass consisting of fibrovascular, myxoid connective tissue stroma interspersed with elongated spindle shaped cells having wavy nuclei. (c) High power photomicrograph (H&E, 40x) showing multiple proliferating spindle shaped and round cells with pale round to oval nuclei. (d) High power photomicrograph (immunoperoxidase staining, 40x) showing strong immunoreactivity for S-100.
CRID2016-3630153.002.jpg
PMC4971312_01_CRID2016-3630153.002.jpg
fig2
Histopathological examination of the section stained with haematoxylin & eosin revealed the presence of a fibrous capsule at some places (Figure 2(a)). The tumor consisted of myxoid connective tissue stroma interspersed with numerous vascular spaces and elongated spindle shaped cells having wavy nuclei (Figure 2(b)). There was also proliferation of multiple spindle shaped cells and round cells with pale round to oval nuclei (Figure 2(c)). The tumor showed strong immunoreactivity for vimentin and S-100 and negative immunoreactivity for CD-68 (Figure 2(d)).