PMC4980503_01
Initial flexible cystoscopic finding. A two-centimeter nonpapillary bladder mass was found at the bladder base with surrounding hypervascularization (arrow).
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Upon presentation to our department, cystoscopy demonstrated a friable two-centimeter broad-based nodule at the bladder base adjacent to the left ureteral orifice with surrounding hypervascularization (Figure 1).
H&E staining on low-powered field. The infiltrative tumor composed of polygonal cells, which arranged in small nests and intervened with blood vessels. These tumor cells posed abundant finely granular eosinophilic to foamy cytoplasm and moderately irregular nuclei.
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fig2
These cells posed abundant fine granular eosinophilic to foamy cytoplasm and irregular nuclei (Figure 2).
Periodic acid Schiff (PAS) staining on high-powered field. The tumor showed positive stain and it demonstrated characteristic diastase-resistant crystalline structures with rhomboid and rod-like structure in some tumor cells (arrow).
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Transcription factor E3 (TFE3) staining on medium-powered field. The tumor showed uniform, strong nuclear positivity against the C-terminus of TFE3.
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