PMC6477468_01
a-c Hemorrhagic bullae and palpable purpura on both the lower extremities and the sole of the foot. d Necrotic lesions on the hands.
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F1
Additionally, numerous hemorrhagic bullae, palpable purpura, and necrotic maculae on the face and upper and lower limbs were found, as well as oral ulcers (Fig. 1).
Necrotizing vasculitis with massive eosinophilic infiltration and a granulomatous reaction.
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F2
Further, a skin biopsy demonstrated perivascular eosinophilic infiltrate and necrotizing vasculitis, as well as a granulomatous reaction (Fig. 2).
a-c Remission of the clinical manifestations after 7 weeks of treatment.
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F3
Seven weeks later, the patient showed up in our clinic with complete clinical and laboratory remission (Fig. 3).