PMC9932368_01
Skin exanthema of various sites due to SDRIFE (A: Flexural forearm, B: Axillar area, C: Posterior neck, C: Inguinal region).
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FIG1
Dermatological examination of the posterior neck and the intertriginous area revealed many bilateral, symmetrical, well-demarcated blue-purple macules and plaques involving the axillary, flexures of the extremities, inguinal, and gluteal regions (Figure 1).
Perivascular inflammation
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FIG2
They revealed focal parakeratosis of the epidermis, significant spongiosis, irregular acanthosis, and perivascular moderately mixed inflammation in the dermis (Figure 2). Based on histology and clinical characteristics, SDRIFE was defined (Figures 2, 3).
Parakeratozis and spongiosis
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FIG3
Based on histology and clinical characteristics, SDRIFE was defined (Figures 2, 3).