PMC3848462_01
Patient aged 70 years with synchronous bilateral breast cancer.
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The LB presented a hard, irregular lump, measuring 20 x 25 mm, with poorly defined edges in the retroareolar region with hard, mobile, and ipsilateral adenopathy (Figure 1).
Bilateral mammogram: mediolateral oblique view showing the presence of lesions highly suspicious for malignancy, BI-RADS category V.
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The bilateral mammogram revealed the presence of a lump in the RB, with diffuse edges, infiltrates, measuring 40 x 35 mm, producing retraction and flattening of the nipple, with pathological microcalcifications in its interior, the spikes of the lump were close to the pectoralis major muscle, while in the LB, a lump was observed measuring 25 x 20 mm with diffuse spiked edges, with pathological microcalcifications both within and outside it (Figure 2).
Haematoxylin-Eosin stain (20x). B12-2165: RB:invasive ductal carcinoma of intermediate-grade malignancy (NGII, BRII), measuring 4.5 x 4 x 3 cm.
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The lymph nodes examined showed two positive lymph nodes (2 of 18) (Figures 3-5).
Haematoxylin-Eosin stain (20x). B12-2166: LB:invasive multifocal ductal carcinoma of intermediate-grade malignancy (NGII, BRII), with papillary and cribriform features, measuring 23 x 20 x 15 cm.
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The lymph nodes examined showed two positive lymph nodes (2 of 18) (Figures 3-5).
Haematoxylin-Eosin stain (20x). B12-2166: LB:invasive papillary carcinoma measuring 25 x 15 x 15 mm.
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The lymph nodes examined showed two positive lymph nodes (2 of 18) (Figures 3-5).