PMC9527531_01
T1 post-contrast axial magnetic resonance imaging of the brain shows
enhancing mass in (A) right posterior parietal lobe and (B) left posterior
parietal lobe with surrounding vasogenic edema.
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On imaging, magnetic resonance imaging (MRI) of the brain revealed a hemorrhagic, lobulated, heterogeneous mass with surrounding vasogenic edema measuring approximately 2.9 x 2.0 x 2.2 cm in posterior parietal lobes, while in the left mid posterior parietal lobe it measured 1.7 x 1.9 x 1.7 cm (Figure 1).
Axial computed tomography image through the mid lung fields showing
cannonball rounded lung lesions bilaterally consistent with metastases.
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Axial computed tomography image through the liver showing heterogeneous
attenuation of the liver parenchyma caused by multiple ill-defined hypodense
liver lesions infiltrating both lobes.
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(A) Metastatic carcinoma in brain: At intermedium magnification (100x), the
carcinoma cells form nests around the veins (indicated by arrow), infiltrate
within the cerebral parenchyma (indicated by arrowhead). (B) At high
magnification (400x), the carcinoma cells demonstrate marked pleomorphism,
vesicular nuclei, high nuclear cytoplasm ratio, irregular nuclear
membranes.
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Ki67 proliferation marker showed brisk mitotic activity (40-50%; Figure 4,5).