PMC5293370_01
Photograph of the patient's subcutaneous hemorrhage (A), Hess chart (orbital Burkitt lymphoma: an aggressive presentation) (B), orbital magnetic resonance imaging of axial (C), and coronal (D) at the first medical examination. White arrows indicate a tumor of the lacrimal gland.
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It was difficult for the patient to open her right eye because of eyelid swelling and subcutaneous hemorrhage (Figure 1A). The Hess chart results indicated an ocular motility disorder (Figure 1B). Magnetic resonance imaging revealed a spherical tumor of the lacrimal gland (Figure 1C and D).
Pathologic examination and tissue immunostaining of the tumor. (A) Hematoxylin and eosin stain (original magnification x400), (B) staining with CD20 (original magnification x400), (C) staining with MiB1 (original magnification x400), (D) staining with CD10 (original magnification x400), (E) staining with Bcl-6 (original magnification x400).
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Hematoxylin and eosin (H&E) staining of the tumor sample revealed a starry sky pattern, and immunohistochemical analysis revealed that the tissue was positive for leukocyte common antigen, CD20, CD10, and Bcl-6 staining; and negative for Bcl-2, CD3, and MUM1 staining, with a MiB1 labeling index of 90-95% (Figure 2).