PMC4897657_01
(A) R-band karyotype showing 47,XY,t(1;5)(?q32;?q21),7p-,+mar1; (B) SKY karyotype from a leukemia cell at the time of diagnosis showing the inverted DAPI (left) and the classified (right) profiles for each chromosome. Translocation t(6;7) (q23;p13), insertion (1;5)(q23;q23q34), and the chromosome 9 are trisome.
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F1
Cytogenetic analysis of bone marrow cells revealed a 47, XY, t(1;5)(q32;q21),7p-,+mar1 karyotype in 20 metaphases analyzed (Figure 1A(Fig. 1)). SKY analysis also showed a complex karyotype involving chromosomes 1, 5, 6, 7 and 9 together with the 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13) (Figure 1B(Fig. 1)).