PMC5312204_01
Erythematous nodule in the right inframandibular region
abd-92-01-0153-gf01.jpg
PMC5312204_01_abd-92-01-0153-gf01.jpg
f1
A 73-year old male patient presented with an asymptomatic erythematous nodule (0.8 x 0.6 x 0.5 cm in size) in the right inframandibular region for about a year (Figure 1).
A) nodules of varying sizes with large amounts of mucin and
stellate cells (Hematoxylin & eosin x20); B) detail of
stellate cells (Hematoxylin & eosin x200)
abd-92-01-0153-gf02.jpg
PMC5312204_01_abd-92-01-0153-gf02.jpg
f2
After surgical excision with 3-mm margins, pathological studies showed multiple nodules of varying sizes, containing abundant mucin and sparse stellate cells in the dermis, consistent with myxoid neurothekeoma (Figure 2).
Immunohistochemistry: A) positivity for vimentin (Hematoxylin
& eosin x200); B) positivity for CD-68 (Hematoxylin &
eosin x40); C) negativity for S-100 in tumor cells and
positivity in the nerve (Hematoxylin & eosin x100); D)
negativity for EMA (Hematoxylin & eosin x20)
abd-92-01-0153-gf03.jpg
PMC5312204_01_abd-92-01-0153-gf03.jpg
f3
Immunohistochemistry was focally positive for CD-68 and diffusely positive for vimentin, but negative for S-100, CD-10, CD-57, EMA, and GFAP (Figure 3).