PMC3317839_01
Transversal CT scans of the thorax from the years 2005 (left) and 2010 (right), showing a solid tumor mass in the left inferior lobe of the lung with almost no progress in size. The tumor had a diameter of approximately 1.7 cm in both 2005 and 2010.
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F1
In March 2010 a 77 year-old male patient was shown to have a tumor mass of about 1.7 cm diameter in the inferior lobe of the left lung (see Figure 1).
A) HE-staining. B-G) Immunohistochemical stainings. B) Cytoplasmatic expression of CK7. C) Nuclear expression of TTF1. D) Cytoplasmatic expression of chromogranin A. E) Cytoplasmatic expression of synaptophysin. F) Plasma membrane associated expression of CD56. G) Ki-67 labelling index of approximately 5%.
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F2
TTF1 showed a strong nuclear and for CK7 a strong cytoplasmatic reaction (see Figure 2). Therefore, the initial diagnosis of a metastasis of prostate cancer was changed to adenocarcinoma of the lung. A and synaptophysin, plasma membrane associated expression of CD56 and a Ki-67 labelling index of approximately 5% (see Figure 2).