PMC8077467_01
Esophagogastroduodenoscopy. A whitish, superficial elevated lesion ( ) in contact with a reddish, superficial depressed lesion ( ) from the anterior wall of the gastric angle and antrum to the lesser curvature on white light imaging (WLI) (a-f).
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F1
EGD revealed a whitish, superficial elevated lesion in contact with a reddish, superficial depressed lesion from the anterior wall of the gastric angle and antrum to the lesser curvature on white light imaging (WLI) (Fig. 1a-f).
Magnifying NBI. An irregular microvascular (MV)/regular microsurface (MS) pattern was shown to be present within the demarcation line in a whitish, superficial elevated lesion (a, b). An irregular MV/irregular MS pattern was shown to be present within the demarcation line in a reddish, superficial depressed lesion (c, d).
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F2
Furthermore, an irregular microvascular (MV)/regular microsurface (MS) pattern was shown to be present within the demarcation line in a whitish, superficial elevated lesion on magnifying NBI (Fig. 2a, b). An irregular MV/irregular MS pattern was shown to be present within the demarcation line in a reddish, superficial depressed lesion on magnifying NBI (Fig. 2c, d).
Specimen mapping and histopathologic examination. The differentiated (tub1-tub2) and undifferentiated (por1-sig) gastric cancers were distinctly localized (shown in yellow and red, respectively) (a). Serial sections of the area showed clear boundaries and no histological transition where the two lesions collided (the left and right sides of the dotted line representing tub1 and por1, respectively) (magnification, x 20) (b).
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F3
The differentiated (tub1-tub2) and undifferentiated (por1-sig) gastric cancers were shown to be distinctly localized on the resected specimen (Fig. 3a). Serial sections of the area showed clear boundaries and no histological transition where the two lesions collided (Fig. 3b).