PMC2413122_01
LOH analysis using markers from chromosome regions a 1pter-p34.3 (D1S199), b 3p26.1-cen (D3S3727), c 17qcen-q21.31 (D17S1872) and d 22q (D22S430) of AT/RT (A), meningioma (M) and myoepithelioma (My) DNAs of the patient. N denotes normal DNA derived from the patient's blood leucocytes. Arrowhead indicates position of lost allele
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Fig1
Presence of LOH in the meningioma, but absence of LOH in AT/RT and myoepithelioma was found for D1S199 in 1pter-p34.3 (Fig. 1a), D2S327 in 2pter-p12, D3S3727 in 3p26.1-cen (Fig. 1b), D16S3020 in 16pter-p12.1 and D17S1872 in 17qcen-q21.31 (Fig. 1c). In contrast, as determined previously and exemplified by marker D22S430 in Fig. 1d, there was LOH for chromosome 22 markers in the AT/RT and myoepithelioma, but not in the meningioma.