PMC5406790_01
Clinical image shows noduloulcerative growth with keratin plugging seen on left vermilion of the lower lip
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F1
Clinical examination revealed a well-defined, nontender, ulcerated, nodular growth measuring approximately 1 cm x 1 cm on the lower lip vermilion [Figure 1].
Histopathological image shows hyperkeratotic epithelium with parakeratin plugging overlying connective tissue stroma with epithelial proliferations superficially in the stroma (H&E, x40)
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F2
The underlying connective tissue stroma showed multiple areas of epithelial tissue entrapment with cystic degeneration in the center and keratinization [Figures 2 and 3].
Histopathological image shows epithelial tissue entrapment with cystic degeneration in the center and keratinization (H&E, x100). Inset (H&E, x400)
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F3
The underlying connective tissue stroma showed multiple areas of epithelial tissue entrapment with cystic degeneration in the center and keratinization [Figures 2 and 3].
Histopathological image shows periodic acid-Schiff-stained section showing negative staining for glycogen granules (H&E, x100). Inset (PAS, x400)
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F4
The epithelial proliferations in the connective tissue did not exhibit PAS positive glycogen granules though [Figure 4].