PMC3817061_01
Fundus photos of the left eye show the progression of the juxtapapillary retinal capillary hemangioma in 2008 (A), 2010 (B), 2011 (C), and 2012 (D).
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No serous retinal detachment or exudates were observed in the macular or peripapillary area (Figure 1A). On subsequent follow-up visits, we noticed a progressive increase in the size of the hemangioma, which in 2012 reached a diameter double that of the optic disc (Figure 1D).
Fluorescein angiography of the left eye in 2008 (A), 2010 (B), 2012 (C and 2013, 6 months after the single intravirtreal injection of ranibizumab (D).
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Fluorescein angiography of the left eye showed early and late hyperfluorescence of the lesion with no leakage (Figure 2A). Also, some exudates and a minimal late leakage were observed in the peripapillary region on fluorescein angiography (Figure 2C). Fluorescein angiography revealed a decrease in the vessels within the hemangioma and a decrease in late leakage (Figure 2D).
The fundus photo of the left eye in 2013, 6 months after the single intravitreal injection of ranibizumab, shows decreased vascularization of the hemangioma and mild fibrosis.
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Six months after the single IVR, fundus examination showed a fibrotic, yellow-white appearance as a result of tumor scarring, and only few vascular channels could be seen within the hemangioma (Figure 3).