PMC4061435_01
Coronal (A) and axial (B, C) CT scan showing biapical fibrotic pleural and subpleural changes (arrows) together with peri-bronchovascular and linear opacities in the upper part of both lungs and normal lower lung zones.
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Moreover septal thickening was mentioned, most pronounced in the subpleural region (Fig. 1).
Pathology specimen obtained by video-assisted thoracoscopic surgery. Masson trichrome stain shows a thickened visceral pleura (asterisk) and subpleural deposition of collagen en elastin (white arrowheads) with an abrupt transition between normal and abnormal parenchyma (black arrowheads). A:x12.5 magnification and B:x100 magnification.
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Additional Masson trichrome and elastin staining revealed marked subpleural collagenous and elastinous deposition with an abrupt transition between abnormal and normal lung parenchyma (Fig. 2).