PMC6354169_01
Clinical photo of the supernumerary nipple on the right (a) and left side (b) of the upper abdominal wall. The one on the right side (a) presents with visible inversion of the supernumerary nipple.
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During a few months before referral, the patient had noticed a firm palpable mass in close relations to the supernumerary nipple on the right side (Figure 1).
Ultrasound of upper abdominal wall right side (a). Ultrasound guided needle core biopsy (16G) of the tumour located on the upper abdominal wall right side (b).
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Ultrasound of the supernumerary nipple on the right side confirmed a small mass in relation to this nipple, presenting as a hypoechoic, well-defined area, measuring approximately 10 mm in diameter (Figure 2). Ultrasound-guided needle core biopsy (16G) was performed (Figure 2(b)).
Micrograph of the needle core biopsy, presenting elongated epithelial islands composed of cubic cells with a small centrally located lumen of cuticles, surrounded by fibrous tissue.
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The microscopic analysis indicated the possibility of SyT and the lesion was categorized as a B3-lesion (a lesion with uncertain malignant potential) (Figure 3).
Excised supernumerary nipple specimen marked as a lumpectomy.
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Micrograph of the tumour. Tumour cords and glands surrounding lactiferous ducts and smooth muscle.
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The tumour was in close association with the lactiferous ducts and smooth muscle of the nipple (Figure 5).
Micrograph of the immunohistochemical analysis showing positive reaction for P63 (a) and CK7 (b).
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Immunohistochemical analysis showed positive reaction for CK5, CK14, and P63 (Figure 6(a)) in association with the epithelium presenting as solid cords, whereas the glandular luminal cells showed positive reaction for CK7 (Figure 6(b)).