PMC3634212_01
Zosteriform metastatic skin-colored solid papules, nodules, and papulovesicles scattered and confluent with few crusted plaques seen on the left side of the neck in a typical zosteriform distribution involving the left C3 dermatome
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F1
Skin-colored solid papules, nodules, and papulovesicles were scattered and confluent and few crusted plaques were seen on the left side of the neck with typical zosteriform distribution consistent with the left C3 dermatome [Figure 1].
A superficial ulcer of 2 x 2 cm over the hard palate in the oral cavity with an eroded surface with irregular margins and pseudomembrane formation
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F2
The ulcer had an eroded surface with irregular margins and had pseudomembrane formation [Figure 2].
Histopathology of oral lesion: section showing hyperplasia of epithelium with central ulceration, necrosis, and inflammatory cells. Area of malignant change seen in the epithelium with few malignant cells breaking into the basement membrane, suggestive of infiltrating squamous cell carcinoma (H and E, x40)
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F3
In one area, there was a malignant change seen in the epithelium with few malignant cells breaking into the basement membrane, suggestive of infiltrating squamous cell carcinoma [Figure 3].
Histopathology of zosteriform lesion: section showing large sheets of malignant squamous cells with hyperchromatic nuclei and mitoses. Central area shows necrosis with overlying squamous epithelium showing hyperplasia in few areas. No malignant change was noted in epidermis. Subcutaneous lymphatics were distended with tumor cells, which was suggestive of squamous cell carcinoma secondaries (H and E, x40)
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F4
Subcutaneous lymphatics were distended with tumor cells, which was suggestive of squamous cell carcinoma secondaries [Figure 4].
Response after external cobalt therapy, showing complete clearance of oral ulcer
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F5
Complete clearance of both the oral cavity ulcer and zosteriform lesions over neck was noted after the radiation therapy [Figures 5 and 6].
Response to cobalt therapy; healing of zosteriform lesions over neck with scarring
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F6
Complete clearance of both the oral cavity ulcer and zosteriform lesions over neck was noted after the radiation therapy [Figures 5 and 6].