PMC5776002_01
(A) Effacement of nodal architecture by proliferation of spindle-shaped histiocytes (100x), (B) High power shows spindle-shaped histiocytes with scattered lymphocytes (400x), (C) Ziehl Neelsen stain shows many acid fast bacilli (1000x) and (D) IHC shows spindle-shaped cells with diffuse positivity for CD68 (400x)
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PMC5776002_01_IJMS-43-94-g001.jpg
F1
Lymph nodal biopsy showed spindle-shaped histiocytes, filled with acid-fast bacilli on Ziehl-Neelsen (ZN) stain, suggestive of MSP (figures 1A-1C). Immunohistochemical (IHC) stains were positive for CD68, S-100 and negative for CD31, which were consistent with MSP (figures 1D, 2A, and 2B).
(A) IHC shows spindle-shaped cells which are positive for S100 (400x) and (B) negative for CD31 (400x)
IJMS-43-94-g002.jpg
PMC5776002_01_IJMS-43-94-g002.jpg
F2
Immunohistochemical (IHC) stains were positive for CD68, S-100 and negative for CD31, which were consistent with MSP (figures 1D, 2A, and 2B).