PMC4357027_01
Anterior segment optical coherence tomography (ASOCT) system with handheld probe and cornea adaptation lens.
CRIOPM2015-506251.001.jpg
PMC4357027_01_CRIOPM2015-506251.001.jpg
fig1
The imaging system is shown in Figure 1.
Anterior segment optical coherence tomography (ASOCT) images during and after Descemet membrane endothelial keratoplasty (DMEK). (a) Intraoperative ASOCT demonstrating single scroll configuration of DMEK donor seen in the anterior chamber. (b) Intraoperative ASOCT showing initial adhesion. (c) Two hours after DMEK showing early adhesion of DMEK donor with small amount of interface fluid. (d) One day after DMEK with further adhesion of donor graft. (e) One week after DMEK demonstrating reepithelization and thinning of central cornea. (f) One month after DMEK showing complete DMEK donor adhesion with remodeling of cornea stroma and further reduction in edema.
CRIOPM2015-506251.002.jpg
PMC4357027_01_CRIOPM2015-506251.002.jpg
fig2
Figure 2 demonstrates high-resolution intraoperative (top images) and postoperative ASOCT scans of the same patient using this portable system. From the serial ASOCT scans we were also able to estimate the corneal thickness, which noticeably reduced from the time of surgery to within 1 hour (664.3 +- 5.6 mum) subsequently 1 day (572.7 +- 9.9 mum) after surgery (t-test, P < 0.001).