PMC3891082_01
Multiple lingual ulcerations (A) and a small penile root ulcer with surrounding erythema (B)
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F1
He had conjunctival injections in both eyes and several aphthous ulcers on the tongue (Figure 1A) and buccal mucosa. A small round ulcer with tenderness was found on the penile root (Figure 1B).
Several round erythematous skin lesions are noted on the chest wall (A) and thigh (B). Swelling of the left knee joint is also seen (B).
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F2
Several round erythematous skin lesions were present on the chest and thigh (Figure 2A). His left knee joint was swollen (Figure 2B) and tender, and needle aspiration revealed turbid inflammatory synovial fluid.
Photomicrograph shows the perivascular mononuclear cell infiltration, extravasation of the red blood cells and fibrinoid necrosis of the vessel wall (H&E stain, x400).
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F3
Skin biopsy was performed and the histologic examination showed perivascular mononuclear cell infiltrations, extravasation of the red blood cells and fibrinoid necrosis of the blood vessel walls; all of these findings were compatible with cutaneous vasculitis combined with BD (Figure 3).
The right auricle shows swelling and redness.
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F4
On the 5th day of admission, both ear auricles became swollen, red and tender (Figure 4).