PMC9763998_01
Changes in platelets and leukocytes after two trastuzumab treatments in the patient. (A) Platelets, (B) white blood cells, and (C) neutrophils.
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F1
Routine blood tests showed a WBC count of 9.82 x 10^9/L, a PLT count of 2 x 10^9/L, and an NE count of 8.79 x 10^9/L (Figures 1A-C). The routine blood test showed that the WBC count was 11.10 x 10^9/L, HGB count was 122 g/L, PLT count was 3 x 10^9/L, and NE count was 10.26 x 10^9/L (Figures 1A-C).
Platelet complement reaction. Trastuzumab was diluted 16,000, 8,000, and 4,000 times, and different samples of platelets reacted with biological complement. (A) Trastuzumab-treated controls without acute hemolysis. (B) Trastuzumab in patients with acute hemolysis.
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F2
Therefore, the extracted platelets were subjected to a complement hemolysis assay (Figure 2).