PMC5227131_01
MRI scan during treatment phases. At diagnosis (a), one month after diagnosis on HREZ (b), after two months of therapy based on resistance assay (c), and after five years (d).
CRIID2016-1841529.001.jpg
PMC5227131_01_CRIID2016-1841529.001.jpg
fig1
Multiple enhancing lesions in the pontomedullary junction, right cerebellum, and left frontal lobe were detected on magnetic resonance imaging (MRI) (see Figure 1(a)). Repeat MRI showed increased oedema and size of the pontomedullary and right cerebellar lesions with hydrocephalus (see Figure 1(b)). Repeat MRI approximately two months after commencement of the MDR TB regimen showed a marked reduction in the size of the right-sided pontine and cerebellar lesions (see Figure 1(c)). He was monitored for the next five years with repeat MRI scanning showing complete resolution of the right cerebellar lesion and continued improvement in the pontomedullary lesion (see Figure 1(d)).