PMC5612604_01
Histopathologic features of the urinary bladder tumor (a, b) and the cutaneous lesion (c, d).
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fig1
TURBT specimen, the presence of malignant tumor segments was ascertained, which were characterized by high cellular density areas. The cytological features of tumor cells included large nuclei with variation in size and prominent nucleoli (Figures 1(a) and 1(b)). III (Figures 1(c) and 1(d)). Immunohistochemical markers were positive for S100, Melan A, and HMB45 and negative for Cytokeratins and EMA.
Melan A immunopositivity in the cells of the TURBT specimen.
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fig2
Immunohistochemical expressions (Table 1) of S100 protein, Melan A (Figure 2), HMB45, and Vimentin were positive, while expressions of Cytokeratin AE1/AE3, Desmin, Chromogranin, and CD99 were negative.