PMC5395270_01
PMC5395270_02
Computed tomography (CT) which reveals a large exophytic mass in the gastric fundus and body with infiltration of the adjacent fat and an adenopathic conglomeration at the level of the gastrohepatic ligament compressing the left lobe of the liver.
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Computed tomography (CT) revealed a large exophytic mass in the gastric fundus and body with infiltration of the adjacent fat and an adenopathic conglomeration at the level of the gastrohepatic ligament compressing the left lobe of the liver, at some points showing an absence of a plane of separation (Figure 1).
Extirpated sample that includes a total gastrectomy, greater and lesser omentectomy, splenectomy, cholecystectomy, and left hepatectomy.
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A total gastrectomy, greater and lesser omentectomy, splenectomy, cholecystectomy and left hepatectomy, and reconstruction using a Roux-en-Y esophagojejunostomy were performed (Figure 2).
(A) Gastric mucosa substituted for a proliferation of keratinized cells that infiltrate the muscle layer (hematoxylin-eosin, original magnification x10) and (B) the tumor nests composed of cells with ample eosinophilic cytoplasm with occasional keratinization (hematoxylin-eosin, original magnification x20).
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Microscopically, the presence of malignant epithelial proliferation was described which grew into a cord-like pattern with frequent images of dyskeratosis (Figure 3); there were anaplastic areas present with a high level of atypia and multinucleated giant cells with a lymphoid response and intense chronic gastritis with marked intestinal-type metaplasia.