PMC6381633_01
Skin prick test and basophil activation test results. Skin prick test (left): a cough syrup GripaNait , containing paracetamol, dextromethorphan, doxylamine, and macrogol 6000; b PEG 1500 1% and 10% (negative), and PEG 4000 1% (positive). Basophil activation test results (right): Q2-1 represents activated basophils CD63+IgE+ (% indicated) and Q4-1 represents non-activated basophils CD63-IgE+. Positive control used anti-IgE antibody and negative control used isotonic solution
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Fig1
Prick tests with GripaNait  (Fig. 1a) and Betadine  gel and solution were positive. All tests were compared with healthy volunteers resulting negative in all of them (Fig. 1). PEG 1500 1% and 10%, but positive with PEG 4000 1% (Fig. 1b). PEG-derivatives also resulted positive in the prick test. BAT resulted positive with PEG 4000 1% and PEG-derivatives (Fig. 1).