PMC3670572_01
Cryostat sections of the patient's muscle biopsy. (a) Hematoxylin and eosin staining reveals clear variations in myofiber size. (b), (c), and (d) ATPase staining at 4.2 (b), 4.6 (c), and 11 (d). The "1" and "2A" in the figure denote type 1 and 2A fibers, respectively. The findings indicate that type 1 fibers were 12% smaller than type 2 fibers, while type 2B fibers were deficient.
CRIM.PEDIATRICS2013-607678.001.jpg
PMC3670572_01_CRIM.PEDIATRICS2013-607678.001.jpg
fig1
Hematoxylin and eosin stains showed clear variations in myofiber size (Figure 1(a)). ATPase stain revealed type 1 fibers that were 12% smaller than type 2 fibers (Figure 1(b)). However, fiber type 1 predominance was not observed, as type 1 fiber accounted for 50.8% of all fibers (Figures 1(b), 1(c), and 1(d)). As illustrated in Figure 1(c), there was a deficiency in type 2B fibers; a finding sometimes observed in CFTD.