PMC3861307_01
(A) Preoperative T1-weighted image (WI) showed a low signal, while fluid-attenuated inversion recovery (FLAIR) scanning showed a high signal and enhanced scanning revealed no signals. An arachnoid cyst was visible in the left temporal region. (B) At the six-month postoperative review there was no tumor recurrence.
ETM-07-01-0061-g00.jpg
PMC3861307_01_ETM-07-01-0061-g00.jpg
f1-etm-07-01-0061
Postoperatively, it was considered that there was an embryonic dysplastic neuroepithelial tumor and left temporal pole arachnoid cyst (Fig. 1).
Intraoperative electroencephalogram EEG and deep cortical electroencephalogram (ECoG) monitoring.
ETM-07-01-0061-g01.jpg
PMC3861307_01_ETM-07-01-0061-g01.jpg
f2-etm-07-01-0061
Intraoperative ECoG and deep EEG were monitored (Fig. 2).
(A and B) Hematoxylin and eosin (H&E) staining showed that a large number of bipolar cells were clustered around and growing along the long axis of the the blood vessel. The cells were positive for human leukocyte differentiation antigen 34 (CD34) (E), CD99 (F) and D2-40 (G), glial fibrillary acidic protein (GFAP) (I), S-100 protein (K) and vimentin (M); however, they were negative for the neuron markers synaptophysin (Syn) (L) and chromaffin protein/NeuN. There was no expression of microtubule-associated protein 2 (MAP2) (C), nestin (D), epidermal growth factor receptor (EGFR) or (H) oligodendrocyte transcriptor-2 (Olig-2). The was expression of (J) epithelial membrane antigen (EMA) but no neurofilament (NF) in the tumor cells. (A) Magnification, x10; (B-D,K,L) magnification, x20; (E-J,M) magnification, x40.
ETM-07-01-0061-g02.jpg
PMC3861307_01_ETM-07-01-0061-g02.jpg
f3-etm-07-01-0061
The Ki-67/MIBk-1 labeling index was ~1% (Fig. 3).