PMC9533140_01
Free light chain concentration of the patient in different treatment stages.
fonc-12-901266-g001.jpg
PMC9533140_01_fonc-12-901266-g001.jpg
f1
Soon after, her lambda FLC concentration increased to 1927.5 mg/L ( Figure 1 ).
Measures of clinical responses to infusions of anti-BCMA CAR-T cells. (A) Concentrations of listed cytokines in serum obtained from the patient at the indicated time points. Day 0 is the day of anti-BCMA CAR-T cell infusion. (B) The results of blood routine tests and (C) serum TNFalpha and IFNgamma concentrations are shown at the indicated time points after anti-BCMA CAR-T cell infusion. (D) The plot shows the changes of the maximum temperature for each day after anti-BCMA CAR-T cell infusion.
fonc-12-901266-g002.jpg
PMC9533140_01_fonc-12-901266-g002.jpg
f2
From Day 6 to Day 9, the patient had high fever and was relieved by glucocorticoids ( Figure 2 ).