PMC3665571_01
External photograph of the eyes showing megalocornea, measured at 16 mm OU.. Abbreviation: OU, oculi uterque.
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Mason, Ohio, USA) at 12 mmHg and 14 mmHg in the right (OD) and left eye (OS), respectively. Megalocorneas were confirmed (16 mm, oculi uterque [OU]) (Figure 1).
Anterior segment photograph showing posterior embryotoxon, an anteriorly displaced Schwalbe's line.. Note: The arrow indicates an anteriorly displaced Schwalbe's line.
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Posterior embryotoxon (Figure 2), ectropion uveae, and iris atrophy were present in both eyes.
Fundus photograph of the right optic nerve depicting an enlarged cup-to-disk ratio. (A) Cup; (B) disk.
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OD; 24.3 mm OS). On fundoscopy, increased cup-to-disk ratios were present (Figure 3).
Axial T2WI depicting iris thinning in association with buphthalmos, enlarged anterior chambers, and lens rounding. (A) Iris thinning in association with buphthalmos, enlarged anterior chambers, and lens rounding. Megalocornea is present with (B) lateralization and flattening of the limbus. (C) The optic nerve sheaths are prominent.. Abbreviation: T2WI, T2-weighted image.
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Orbit MR demonstrated lateralization and flattening of the limbus representing megalocornea (Figure 4). Thin section T2WI showed bilateral iris thinning as subjectively judged by two neuroradiologists (MW and AC) (Figure 4). Increased axial length (24.2 mm OD and 24.6 mm OS), enlarged anterior segments (3.6 mm anteroposterior dimension, OU), lens rounding, bilateral optic nerve excavation, and optic nerve sheath prominence were also present (Figures 4 and 6), as compared to a normal orbital MRI in an aged-matched patient (Figure 5).
Axial T2WI from a normal orbital MR in an aged-matched patient demonstrating a normal oval lens morphology, the normal angle of the limbus, and a normal optic nerve-sheath complex. (A) Normal oval lens morphology; (B) normal angle of the limbus; (C) normal optic nerve-sheath complex.. Note: The normal lens is not well depicted in this section.. Abbreviations: T2WI, T2-weighted image; MR, magnetic resonance.
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Increased axial length (24.2 mm OD and 24.6 mm OS), enlarged anterior segments (3.6 mm anteroposterior dimension, OU), lens rounding, bilateral optic nerve excavation, and optic nerve sheath prominence were also present (Figures 4 and 6), as compared to a normal orbital MRI in an aged-matched patient (Figure 5).
Sagittal reformation of thin section T1-weighted orbital images demonstrating enlarged cup-to-disk ratios bilaterally with optic nerve excavation.. Notes: Arrows depict enlarged bilateral cup-to-disk ratios with optic nerve excavation. Buphthalmos, deep anterior chambers, and lens rounding are also depicted.
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Increased axial length (24.2 mm OD and 24.6 mm OS), enlarged anterior segments (3.6 mm anteroposterior dimension, OU), lens rounding, bilateral optic nerve excavation, and optic nerve sheath prominence were also present (Figures 4 and 6), as compared to a normal orbital MRI in an aged-matched patient (Figure 5).
Sagittal FSPGR BRAVO image through the right mandible of our patient and a normal child. (A) Sagittal FSPGR BRAVO image through the right mandible of our patient showing evidence of a second deciduous mandibular molar taurodontia manifested by enlarged pulp chamber-to-root ratio (arrow). (B) Sagittal FSPGR BRAVO image through the right mandible of a 19-month-old normal child showing a normal second deciduous mandibular molar for comparison (arrow).. Abbreviation: FSPGR BRAVO, fast spoiled gradient echo brain volume.
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Sagittal FSPGR BRAVO image displaying a 4 mm pars intermedia pituitary cyst within an otherwise normal pituitary gland, a relatively steep clival angle, and a 4 mm pineal cyst is present. (A) A 4 mm pars intermedia pituitary cyst within an otherwise normal pituitary gland. (B) There is a relatively steep clival angle. (C) A 4 mm pineal cyst is present. Also note mild brachycephaly.. Abbreviation: FSPGR BRAVO, fast spoiled gradient echo brain volume.
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Brain MR demonstrated a 4 mm uncomplicated pineal cyst and a 4 mm pars intermedia cyst associated with an otherwise normal pituitary gland (Figure 8). The clivus was somewhat steep, with a clival angle of 111 degrees (Figure 8). Mild brachycephaly was also evident (Figure 8).