PMC3336226_01
Blood cell counts during hospitalization. Abbreviations: IL-11: interleukin-11; G-CSF: granulocyte-colony stimulating factor; Imm.Glob: human immunoglobulins.
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fig1
Within 48 h, patient developed fever, severe neutropenia, thrombocytopenia, and a more profound lymphocytopenia (Figure 1) and skin and lung bleeding.
Bone marrow study: (a) mild hypocellularity. (b) Positive histiocytes stain for CD68 marker. (c) Myeloid cell line composed mostly of promyelocytes with prominent Golgi apparatus and absent neutrophils and metamyelocytes (maturation arrest). (d) Histiocytes and promyelocyte (center) with a rare histiocyte showing hemophagocytosis.
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fig2
Bone marrow examination findings are shown in Figure 2.