PMC3649607_01
(a, b) Penile ulcerated lesion and papule at pubic area before treatment; (c, d) Appearance at three months (c) and six months (d) after treatment
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F1
Physical examination demonstrated two areas of painless indurated lesions at the pubic area and shallow ulceration on the penil shaft [Figures 1a and b] and bilateral palpable inguinal lymphadenopathy. Complete resolution of penile, pubic lesions and inguinal adenopathy was achieved at six months of treatment [Figures 1c and d].
Histological appearance of granulomatous inflammation with caseous necroses (H and E, x10)
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F2
The pathologic examination of biopsy samples from endurated pubic lesions demonstrated granulomatous inflammation with caseous necroses [Figure 2] and multinucleated giant cells of Langhans type, which was compatible with BCG-induced granulomatous skin infection.