PMC3937484_01
Multiple hyperpigmented patches in a cribriform pattern along the lines of Blaschko
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F1
Cutaneous examination revealed linear, cribriform, brown to black pigmentation along lines of Blaschko extending from back to abdomen till pubic area on right side [Figure 1].
Skin biopsy showing moderate epidermal hyperplasia with increased basal layer pigmentation. (H and E, x40)
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F2
A skin biopsy specimen was obtained from most recent lesion which revealed uniformly increased pigmentation within the basal keratinocytes [Figures 2 and 3].
Uniformly increased basal layer pigmentation with pigmented basal layer keratinocytes (H and E, x100)
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F3
A skin biopsy specimen was obtained from most recent lesion which revealed uniformly increased pigmentation within the basal keratinocytes [Figures 2 and 3].
High power view of one of the rete-ridge showing increased melanin pigmentation and mild pigment incontinence (H and E, x400).
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F4
There were few dermal melanophages with mild pigment incontinence without much inflammatory infiltrate in the dermis [Figure 4].