PMC2718187_01
A 54-year-old woman with gallbladder cancer and solitary necrotic nodule of the liver.. A. CTAP shows an ovoid-shaped area of portal perfusion defect (arrows), 1.0 cm in diameter, in the right hepatic lobe.. B. CTHA shows a highly enhancing nodular lesion (arrows) in the same area.. C. Intraoperative US shows an additional target-appearing hypoechoic nodule (arrows), 0.5 cm in diameter, in the same segment of the liver.. D. Photomicrograph shows central amorphous necrosis (arrows) surrounded by a fibrotic capsule, with infiltration by inflammatory cells (arrowheads) (hematoxylin-eosin stain, x13).
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F1
An ovoid portal perfusion defect area was demonstrated by CTAP (Fig. 1A), and a highly enhancing nodular lesion in the same area of the right lobe of the liver by CTHA (Fig. 1B). In addition, two other nodules each with a diameter of 0.5 cm, were present in the same segment of the liver (Fig. 1C). The hepatic nodules were diagnosed as a solitary necrotic nodule composed of a central necrotic core and a peripheral fibrotic capsule with inflammatory cells (Fig. 1D).
PMC2718187_02
A 72-year-old man who six years earlier had undergone subtotal gastrectomy due to gastric cancer.. A. Contrast-enhanced CT shows an elliptical hypoattenuating nodule (arrow) in the lateral segment of the liver.. B. Contrast-enhanced T1-weighted MR image shows a subtle peripheral enhancing nodule (arrow) at the same site.
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F2
In addition, an elliptical, hypoattenuating nodule measuring 1.0 x 0.3 cm in diameter was observed in the lateral segment of the left lobe of the liver (Fig. 2A). T2-weighted MR imaging (T2WI) indicated that a nodule at the same site was hyperintense, and T1WI that it was isointense, while Gadolinium-enhanced study suggested the presence of a subtle, peripheral enhancing nodule (Fig. 2B).