PMC3364052_01
Large ano-rectal ulcer on exam under anesthesia.
CRIM2012-537278.001.jpg
PMC3364052_01_CRIM2012-537278.001.jpg
fig1
She was taken to the operating room and examination demonstrated a large deep anal canal ulcer in the left posterior-lateral position (Figure 1).
Rectal biopsy showing mucosal and submucosal atypical hematopoietic cell infiltration.
CRIM2012-537278.002.jpg
PMC3364052_01_CRIM2012-537278.002.jpg
fig2
Refer to Figures 2, 4, 5 and 6.
Anal ulcer biopsy showing atypical mucosal and submucosal hematopoietic cell infiltration.
CRIM2012-537278.003.jpg
PMC3364052_01_CRIM2012-537278.003.jpg
fig3
Biopsies were taken from the anal ulcer and rectosigmoid mucosa (Figure 3).
Rectal ulcer biopsy under high magnification shows atypical large and medium hematopoietic cells with large irregular nuclei and pale cytoplasm. Scattered small lymphocytes and plasma cells also seen.
CRIM2012-537278.004.jpg
PMC3364052_01_CRIM2012-537278.004.jpg
fig4
Refer to Figures 2, 4, 5 and 6.
Immunohistochemical marker staining.
CRIM2012-537278.005.jpg
PMC3364052_01_CRIM2012-537278.005.jpg
fig5
Refer to Figures 2, 4, 5 and 6.
Bone marrow biopsy showing hypercellularity and atypical cells.
CRIM2012-537278.006.jpg
PMC3364052_01_CRIM2012-537278.006.jpg
fig6
Refer to Figures 2, 4, 5 and 6.