PMC4075794_01
In A, chest X-ray showing bilateral hilar lymphadenopathy and slight
effusion on the right. In B, CT scan of the chest showing multiple swollen
lymph nodes and subpleural nodules.
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In addition, there was an abnormal shadow with multiple swollen lymph nodes on chest X-ray and CT scans (Figure 1).
In A, bone marrow aspirate showing metastasis of small cell lung cancer
(H&E; magnification, x400). In B, tumor cells testing positive for
anti-cytokeratin (AE1/AE3; immunohistochemical staining; magnification, x400).
In C, tumor cells testing positive for thyroid transcription factor-1 (TTF-1;
immunohistochemical staining; magnification, x400). In D, tumor cells testing
positive for synaptophysin (immunohistochemical staining; magnification,
x400).
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Bone marrow aspiration revealed bone marrow metastasis of SCLC (Figure 2).