PMC6082349_01
Contrast-enhanced CT of pulmonary revealed bilateral pulmonary metastases (arrow).. Abbreviation: CT, computed tomography.
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Subsequent pulmonary enhanced computed tomography (CT) scan showed multiple metastatic tumors in both lungs (Figure 1).
Enhanced MRI of prostate.. Notes: (A) Prostate was enlarged in size (4.2x4.7x6.2 cm) with multiple high signals of small nodules (arrow). (B) Multiple enlarged lymph nodes in pelvic cavity (arrow).. Abbreviation: MRI, magnetic resonance imaging.
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Also, multiple enlarged lymph nodes in the pelvic cavity were found (Figure 2).
Histopathology of prostate biopsy.. Notes: Postoperative histopathology of prostate revealed poorly differentiated transitional cell carcinoma (A) (H&E, 40x) and (B) (H&E, 200x). Histochemical staining of tumor cells for (C) P504S(+) and (D) 34betaE12(+++).. Abbreviation: H&E, hematoxylin and eosin.
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Immunohistochemical staining showed the tumor cells were positive for cytokeratin (CK) 20(+), CK7(+), CK8/18(+++), CK5/6(+++), 34betaE12(+++), and P504S(+), but negative for CK34, D2-40, uroplakin, and PSA (Figure 3).