PMC7656036_01
Sagittal (a) and axial T2-weighted (b) images demonstrated an intradural extramedullary cervical spine mass, displacing the spinal cord anteriorly and to the left. Axial T1 precontrast (c) and axial T1 postcontrast images (d) demonstrate heterogeneous enhancement of the mass, with a convex border abutting the spinal cord.
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F1
The cervical MRI demonstrated a T1 isointense, T2 hyperintense, enhancing intradural, extramedullary mass measuring 2.4 x 1.4 x 1.1 cm at the C5-C6 level [Figure 1].
Hematoxylin and eosin stain (a) shows an astrocytic neoplasm with moderately pleomorphic nuclei and many eosinophilic granular bodies. Periodic acid-Schiff with diastase (b) highlights the eosinophilic granular bodies as well as blood vessels. By immunohistochemistry, the tumor cells show cytoplasmic positivity for GFAP (c) and synaptophysin (d), nuclear positivity for SOX10 (e), and both nuclear and cytoplasmic positivity for S-100 (f). (a,b) Viewed at x200 magnification. (c-f) Viewed at x400 magnification.
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F2
The tumor was a well-circumscribed neuroepithelial neoplasm arranged in fascicles, sheets, and nests [Figure 2].
Sagittal T2-weighted (a) and T1 FS postcontrast (b) images of the cervical spine demonstrate no residual or recurrent tumor 7 months postoperatively.
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F3
On follow-up MR 7 months later, the tumor had not recurred [Figure 3].