PMC9091902_01
Brain MRI of the cases. (A) Case 1: axial T1 post-gadolinium sequence (A1) and FLAIR sequence (A2). (B) Case 2: axial T1 post-gadolinium sequence. (C) Case 3: axial T2 sequence. (D) Case 4: axial FLAIR sequence on day -1 (D1) and on day +21 (D2) with respect to vaccination.
fneur-13-897275-g0001.jpg
PMC9091902_04_fneur-13-897275-g0001.jpg
F1
Brain and spinal MRI performed at the time of presentation revealed a total of 10 lesions, most of them periventricular (Figure 1D1), ovoid-shape in appearance, >1 cm in size, and 2 infratentorial lesions (in right cerebellar peduncle and in the pons), 3 of which presented gadolinium enhancement. At this time, there were no other signs suggestive of infectious etiology (Figure 1D1). HSV-1 encephalitis (Figure 1D2). He was started on acyclovir, 6 sessions of PLEX every other day, 1,000 mg MP IV for 5 days, and two doses of 1,000 mg rituximab IV separated by 2 weeks.
PMC9091902_02
Brain MRI of the cases. (A) Case 1: axial T1 post-gadolinium sequence (A1) and FLAIR sequence (A2). (B) Case 2: axial T1 post-gadolinium sequence. (C) Case 3: axial T2 sequence. (D) Case 4: axial FLAIR sequence on day -1 (D1) and on day +21 (D2) with respect to vaccination.
fneur-13-897275-g0001.jpg
PMC9091902_04_fneur-13-897275-g0001.jpg
F1
Brain and spinal MRI performed at the time of presentation revealed a total of 10 lesions, most of them periventricular (Figure 1D1), ovoid-shape in appearance, >1 cm in size, and 2 infratentorial lesions (in right cerebellar peduncle and in the pons), 3 of which presented gadolinium enhancement. At this time, there were no other signs suggestive of infectious etiology (Figure 1D1). HSV-1 encephalitis (Figure 1D2). He was started on acyclovir, 6 sessions of PLEX every other day, 1,000 mg MP IV for 5 days, and two doses of 1,000 mg rituximab IV separated by 2 weeks.
PMC9091902_03
Brain MRI of the cases. (A) Case 1: axial T1 post-gadolinium sequence (A1) and FLAIR sequence (A2). (B) Case 2: axial T1 post-gadolinium sequence. (C) Case 3: axial T2 sequence. (D) Case 4: axial FLAIR sequence on day -1 (D1) and on day +21 (D2) with respect to vaccination.
fneur-13-897275-g0001.jpg
PMC9091902_04_fneur-13-897275-g0001.jpg
F1
Brain and spinal MRI performed at the time of presentation revealed a total of 10 lesions, most of them periventricular (Figure 1D1), ovoid-shape in appearance, >1 cm in size, and 2 infratentorial lesions (in right cerebellar peduncle and in the pons), 3 of which presented gadolinium enhancement. At this time, there were no other signs suggestive of infectious etiology (Figure 1D1). HSV-1 encephalitis (Figure 1D2). He was started on acyclovir, 6 sessions of PLEX every other day, 1,000 mg MP IV for 5 days, and two doses of 1,000 mg rituximab IV separated by 2 weeks.
PMC9091902_04
Brain MRI of the cases. (A) Case 1: axial T1 post-gadolinium sequence (A1) and FLAIR sequence (A2). (B) Case 2: axial T1 post-gadolinium sequence. (C) Case 3: axial T2 sequence. (D) Case 4: axial FLAIR sequence on day -1 (D1) and on day +21 (D2) with respect to vaccination.
fneur-13-897275-g0001.jpg
PMC9091902_04_fneur-13-897275-g0001.jpg
F1
Brain and spinal MRI performed at the time of presentation revealed a total of 10 lesions, most of them periventricular (Figure 1D1), ovoid-shape in appearance, >1 cm in size, and 2 infratentorial lesions (in right cerebellar peduncle and in the pons), 3 of which presented gadolinium enhancement. At this time, there were no other signs suggestive of infectious etiology (Figure 1D1). HSV-1 encephalitis (Figure 1D2). He was started on acyclovir, 6 sessions of PLEX every other day, 1,000 mg MP IV for 5 days, and two doses of 1,000 mg rituximab IV separated by 2 weeks.