PMC9722770_01
(A, B) Biopsy pathology. (August 7, 2020).
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A biopsy with histopathological examination suggested adenocarcinoma with high-grade squamous intraepithelial lesions ( Figures 1A, B ).
(A, B) Abdominal computed tomography (August 5, 2020).
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Whole-abdominal contrast-enhanced computed tomography (CT) revealed a soft tissue mass on the upper left side of the vaginal stump with a maximum size of 4 cm x 3 cm, left renal effusion, atrophy, and multiple enlarged lymph nodes in the retroperitoneal area, indicating metastasis ( Figures 2A, B ).
(A, B) Pelvic magnetic resonance imaging (September 23, 2020).
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October 31, 2020 (50.4 Gy/28f) for vaginal dissection lesions. On evaluation after radiotherapy, partial remission was noted ( Figures 3A, B ).
(A, B) Colposcopy and biopsy pathology (January 27, 2021).
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After three sessions of chemotherapy, a 1*1cm nodule with a brittle texture was seen in the middle 1/3 of the anterior vaginal wall, and biopsy pathology suggested squamous carcinoma ( Figures 4A, B ).
(A, B) Urinary tract computed tomography urography (October 24, 2021).
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Hyperechogenicity was noted in the vagina with a size of approximately 7.15 cm x 4.30 cm x 4.42 cm ( Figures 5A, B ).
(A-C) Abdominal computed tomography (January 6, 2022).
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A review of the left posterior wall of the bladder revealed a region with slightly lower echogenicity, measuring approximately 4.17 cm x 3.20 cm x 4.42 cm ( Figures 6A-C ).
(A, B) Pelvic magnetic resonance imaging (May 17, 2022).
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At present, five courses of this regimen have been administered, and complete response has been achieved ( Figures 7A, B ) (HPV negative; SCC antigen level, 0.81 ng/mL).