PMC10176189_01
Fundus photography (a, e, i), autofluorescence imaging (b, f, j), and SD-OCT B-scans (d, h, l) of torpedo lesions in the temporal macula for patient #1 (a-d), patient #2 (e-h), and patient #3 (i-l). There is diffuse hypo-autofluorescence throughout each torpedo lesion (b, f, j). Each lesion variably demonstrates retinal cavitation (red arrows), outer retinal atrophy (yellow arrows), and intraretinal hyperreflectivity (blue arrows) (d, h, l).
cop530005_f01.jpg
PMC10176189_01_cop530005_f01.jpg
F1
Dilated fundus examination revealed well-circumscribed, globally hyperpigmented lesions with patchy hypopigmentation among all 3 patients (Fig. 1a, e, i). SD-OCT findings of loss of outer retinal layers and focal hyperreflectivity, consistent with hyperpigmentation as well as shadowing artifact posterior to areas of hyperreflectivity consistent with pigment migration (Fig. 1d, l). SD-OCT of patient #2 showed outer retinal atrophy but did not reveal the same hyperreflectivity (Fig. 1h). SD-OCT imaging for patients #1 and #3 also demonstrated cavitation of the outer retinal layers and loss of the ellipsoid zone (Fig. 1d, l). FAF showed homogenous hypo-autofluorescence consistent with diffuse RPE irregularity in all 3 patients (Fig. 1b, f, j). All relevant photos are shown in Figure 1.