PMC4678085_01
(a) Exophytic granulomatous lesion in 16 and 17 implants. (b) Palatal view of the granulomatous lesion in 16 and 17. (c) Granulomatous lesion in 36.
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They were associated with the gingiva, located on the buccal and palatal/lingual sides of implants 3.6, 1.6, and 1.7 (Figure 1).
(a) Periapical radiograph that shows bone loss in implants 16 and 17. (b) Periapical radiograph that shows bone involvement in implant 36.
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The microscopic description was that of ulcerated lesions covered by a fibrin and leukocyte membrane and made up of granulation tissue with a mixed inflammatory infiltrate with polymorphonuclears, together with vascular proliferation (Figure 2).
(a) 12-month postexcision follow-up of the lesion in 16 and 17 area. (b) Palatal view of the 12-month postexcision follow-up of the lesion in 16 and 17. (c) 12 month postexcision follow-up of the lesion in 36.
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Postoperatively there were no further issues and there was no evidence of relapse at 12-month follow-up (Figure 3).
PMC4678085_02
(a) Exophytic granulomatous lesion in 4.6. (b) Periapical radiograph that shows bone involvement in implant 46.
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Periapical radiograph revealed bone loss of 4 mm affecting both the mesial and distal surfaces of the implant (Figure 4).
Histopathology of peripheral giant-cell granuloma.
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Histopathology confirmed that it was an ulcerated peripheral giant-cell granuloma, without suggestion of malignancy (Figure 5).
12-month postexcision follow-up of the lesion located in 46.
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Postoperative healing was good and at 12-month follow-up there was no evidence of recurrence (Figure 6).