PMC9399781_01
Preoperative images of a 27-year-old man with intraventricular hemangioblastoma. (A) CT scans showed a 3.5 cm hypo-isodense mass located in the left lateral ventricle. (B-F) MRI revealed a solid-cystic mass, and the solid part of mass was mildly heterogeneously enhancing.
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T1-weighted images and hyper-intense on T2-weighted images. The solid part of the mass was slightly heterogeneously enhanced after enhancement ( Figure 1 ).
Anterior interhemispheric approach for hemangioblastoma. Arrow in (A) Arteria pericallosal. Arrow in (B) Intraventricular tumor with abundant blood supply, unclear boundary and brittle texture .
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Figure 2 ). Finally, a ventricular drain was placed into the left lateral ventricle after removing all the visible parts of the tumor and after performing a meticulous intraventricular hemostasis.
Pathological examination after surgery. Tumors were composed of capillaries and stromal cells of different maturation stages, some of which are mildly atypical, we considered hemangioblastoma (WHO grade I) as the final diagnosis. Tumor tissue: Ki-67(2%+), P53(<1%+), CD56(-), NSE(-), Syn(+), EMA(+), CgA(-), PR(-), SALL4(-), GFAP(+\-), S-100(--), CKpan(-), Vim(+), Myoglobin(-), CD34(Endothelial cells+), D2-40(+), TTF-1(-), Inh-alpha(-), CD10(-).
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The histopathological results of the mass indicated HB, which was not considered among our preoperative diagnoses ( Figure 3 ).
The postoperative CT (A), T1-weighted (B), and T2-weighted MRI (C) after one month showed good tumor resection.
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The follow-up after one month still revealed the absence of the tumor with normal ventricle morphology as shown by CT and MRI ( Figure 4 ).