PMC7573727_01
Chest CT findings of the case 1. Chest CT showed bilateral diffuse small nodular shadows which presented with typical tree-in-bud pattern. Figure 1(A), 1(B), 1(C), 1(D), 1(E), 1(F) are the chest CT of the patient at the first diagnosis, 2 months, 4 months, 16 months, 18 months and 26 months later, respectively.
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Chest high-resolution computed tomography (HRCT) scan showed well-defined multiple centrilobular nodules and diffuse tree-in-bud pattern (Figure 1A).
Paranasal sinus CT findings of case 1 and case 2. Figure 2A and 2B are sinus CT of case 1. Figure 2C and 2D are sinus CT of case 2. Inflammatory lesion of maxillary sinus (red arrows). Inflammatory lesion of ethmoid sinus (blue arrow).
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CT showed bilateral maxillary sinusitis and ethmoid sinusitis (Figure 2C, 2D). Cold agglutinin level was in the normal range.
Dynamic chest CT changes of pulmonary tuberculosis lesions in case 1. Figure 3(A), 3(B), 3(C), 3(D), 3(E), 3(F) are the chest CT of case 1 at the first diagnosis, 2 months, 4 months, 16 months, 18 months and 26 months later, respectively. Figure 3(D) shows the pulmonary tuberculosis lesion of the patient (green arrows).
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Chest CT showed a small nodule at the upper tip of the right lung (Figure 3D). The patient's condition gradually improved and the nodule in the right lung showed significant shrinkage (Figure 3E, 3F) after anti-tuberculosis treatment.
The bronchoscopy findings of case 1. There were abundant purulent secretions in the bronchi.
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Fiberoptic bronchoscopy revealed abundant purulent secretions in the left and right main bronchi and all levels of bronchi (Figure 4).
PMC7573727_02
Paranasal sinus CT findings of case 1 and case 2. Figure 2A and 2B are sinus CT of case 1. Figure 2C and 2D are sinus CT of case 2. Inflammatory lesion of maxillary sinus (red arrows). Inflammatory lesion of ethmoid sinus (blue arrow).
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CT showed bilateral maxillary sinusitis and ethmoid sinusitis (Figure 2C, 2D). Cold agglutinin level was in the normal range.
Chest CT findings of the case 2. Chest CT showed bilateral diffuse small nodular shadows and bronchiectasis. Figure 5(A, G), 5(B, H), 5(C, I), 5(D, J), 5(E, K), 5(F, L) are the chest CT of the patient at the first diagnosis, 1 months, 3 months, 8 months, 16 months and 25 months later, respectively.
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Chest CT showed bronchiectasis and diffuse small nodules in both lungs (Figure 5).
Sinus CT of the younger brother (figure 6A) and the father (figure 6B). Inflammatory lesion of maxillary sinus (red arrows).
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The results showed no obvious abnormalities in their chest CT, but father's sinus CT showed bilateral maxillary sinus inflammation (Figure 6B).