PMC7145153_01
Flexible sigmoidoscopy on day 3 showing severe rectal inflammation.
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F1
Flexible sigmoidoscopy performed on day 3 displayed severe inflammation up to 60 cm depth of insertion (Figure 1).
Hematoxylin & eosin stain on day 3 showing necrotic mucosa with acute inflammation and purulent exudate.
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F2
A biopsy revealed necrotic mucosa and purulent exudate, but no crypt abscesses (Figure 2).
Flexible sigmoidoscopy on day 10 showing inflamed rectal mucosa improved from previous examination.
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F3
Repeat flexible sigmoidoscopy up to 30 cm depth on day 10 demonstrated improved severity of proctocolitis (Figure 3).
Hematoxylin & eosin stain on day 10 showing healed mucosa with granulation tissue.
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F4
Biopsy showed ulceration and granulation tissue of the rectum, but no pathologic changes of the sigmoid colon (Figure 4).