PMC8794395_01
The patient, a 73-year-old male, presented with a persistent cough found to have a large posterior mediastinal mass on imaging. Further chest computed tomography angiography (CTA) to characterize the lesion demonstrated a 6.3x5.7x11.5 cm3 mass. CTA chest (coronal) with 3D reconstruction demonstrating mediastinal tumor (highlighted in blue) encroachment of the aortic arch and left subclavian artery.
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Further chest CT angiography (CTA) demonstrated a 6.3x5.7x11.5 cm3 mass in the posterior superior mediastinum between the trachea and left subclavian artery, abutting the aortic arch, with mass effect on the trachea and esophagus (Figures 1,2).
A 73-year-old male with a persistent cough, found to have a posterior mediastinal mass with initial biopsy consistent with a schwannoma. He underwent surgical resection of the mediastinal mass, requiring vascular reconstruction due to extensive involvement of the left subclavian vein. Final pathology revealed two separate schwannomas, 11 and 3.5 cm, with negative margins. (A) Gross anatomical specimen of mediastinal schwannoma measuring 11 cm in length; (B) histological image of the tumor with hematoxylin-eosin (H&E) staining at 100x magnification demonstrating uniformly spindle shaped Schwann cells.
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Final pathology revealed two separate Schwannomas, one 11 cm, the other 3.5 cm, each completely excised with negative margins, with 45 benign lymph nodes (Figure 3).