PMC9331163_01
FLAIR images showing the lesion. Images are spaced by 5 mm.
fneur-13-869248-g0001.jpg
PMC9331163_01_fneur-13-869248-g0001.jpg
F1
Lesion volume was 43.0 cm3 and did not overlap with the corticospinal tract, suggestive of intact descending motor pathways (see Figure 1).
Timeline of treatment and clinical outcomes. High-frequency rTMS treatment to the left dorsolateral prefrontal cortex was delivered during the blue phases, with daily sessions from week 0-2 (darker blue) and weekly sessions from week 11-22 (lighter blue). No rTMS treatment was provided between these times. Threshold for a clinically meaningful improvement from baseline for both the Beck Depression Inventory and Patient Health Questionnaire is shown with a horizontal dotted line. Data points below the dotted line indicate a clinically meaningful improvement in depression.
fneur-13-869248-g0002.jpg
PMC9331163_01_fneur-13-869248-g0002.jpg
F2
Clinical outcomes and timeline are shown in Figure 2.