PMC7843414_01
Timeline of patient's clinical presentation, diagnosis and treatment. Clinical features (solid black lines), diagnosis (black dotted lines), treatment (solid gray lines), hypothesis (dashed black lines) and hematopoietic stem cell transplantation (HSCT) outcome (double dashed lines) are indicated.
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In spite of the good response obtained through second-line therapy, the splenomegaly persisted, and later the gall bladder was surgically removed because of acute cholecystitis ( Figure 1 ).