PMC5124683_01
Brain MRI with bilateral peripherally enhancing white matter lesions representing signs of active demyelination.
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CT revealed new bifrontal multifocal white matter hypoattenuation, while MRI brain (see Figure 1) revealed bilateral peripherally enhancing white matter lesions and signs of demyelination. Cerebrospinal Fluid (CSF) PCR was positive for the JC virus.
Interval improvement in enhancing white matter lesions consistent with clinical improvement.
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Remarkably, he has since cleared the CSF of the JC virus on follow-up labs and shown substantial interval imaging improvement on recent MRI (Figure 2).