PMC3914346_01
PMC3914346_02
Perfusion CT correlating with DSA. CT perfusion with MTT (sec) (a), TTP (sec) (b), CBF (mL/100 g/min) (c), and CBV (mL/100 g) (d) showing circumscribed perfusion deficit on the territory of the left MCA. No evidence of infarction as shown on native CT scan (f). Digital subtraction angiography (e, g) of the left ICA from the same patient on the same day showing vasospasm of the left ICA above the ophthalmic artery of the median and anterior cerebral artery.
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fig2
Perfusion CT scans showed vasospasm related changes in 90% of our cases and showed improvement correlating with angiographic results and clinical symptoms; see Figure 2.
Correlation of H&H grade and patient outcome. Spearman rank test shows inverted correlation of Hunt & Hess grade on admission and outcome (GOS) on discharge.
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fig3
Hunt & Hess did not predict the duration of therapy (Spearman r = 0.07569 (corrected for ties), 95% confidence interval: -0.3028 to 0.4336, two-tailed P value is 0.6910), but the Spearman rank correlation test showed significant difference in outcome (Spearman r = -0.4353 (corrected for ties), 95% confidence interval: -0.6936 to -0.07778, two-tailed P value is 0.0162); see Figure 3.
Correlation of onset of selective continuous intra-arterial nimodipine infusion and patient outcome. Spearman rank test shows that inverted correlation of the day nimodipine infusion was started with the outcome (GOS) on discharge.
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fig4
The onset of continuous intra-arterial nimodipine treatment significantly correlates with the outcome (GOS) (Spearman r = -0.4070 (corrected for ties), 95% confidence interval: -0.675 to -0.04351, two-tailed P value is 0.0256); see Figure 4.
Linear correlation test shows extremely high significance of ptiO2 and rCBF values during (day 1) selective continuous intra-arterial nimodipine infusion.
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fig5
We have picked out "day one" to show correlation (correlation coefficient (r) = -0.7348, 95% confidence interval: -0.8829 to -0.4538, coefficient of determination (r squared) = 0.5400, two-tailed P value is <0.0001); see Figure 5.