PMC7160763_01
Electroencephalogram recorded during interseizure period on day 5. Sharp
waves were recorded in the right frontal region (red box). These waveforms
also showed disruption of background activity and subsequent emergence of
slow waves. Low resolution and clipping traces are due to malfunction of the
recording device.
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EEG during FIAS showed rhythmic 5-9 Hz theta activity in the right frontotemporal region (data not shown). EEG recorded during an interseizure period revealed irregular right frontal sharp waves with theta and delta activities (Figure 1).
Coronal fluid attenuation inversion recovery magnetic resonance imaging of
the brain on day 5. Bilateral atrophy of the hippocampus is observed (white
arrows). No other clear abnormal findings, including ischemic
leukoencephalopathy, were found. Diffusion-weighted imaging of the brain
showed no significant abnormalities.
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Magnetic resonance imaging (MRI) of the brain showed no obvious signs suggesting osmotic demyelination syndrome (ODS); however, marked atrophy of the hippocampus and temporal lobe was seen (Figure 2).