PMC9296265_01
Echocardiographic findings. Case 1 (
A, B
): short axis of the AV in transesophageal echocardiography. Case 2 (
C, D
): long axis of the left ventricular outflow tract, aortic valve, and root in transesophageal echocardiography. Pictures A and C show brightness mode of the AV without central coaptation (*). Pictures B, and D display the regurgitation jet (#) in a color Doppler mode.
10-1055-s-0042-1750408-i210422crc-1.jpg
PMC9296265_01_10-1055-s-0042-1750408-i210422crc-1.jpg
FI210422crc-1
Histomorphology
.
Displayed are histological findings (Movat pentachrome-stain) in case 1 (
A
) and case 2 (
B
). As comparison, non-dilated aortic wall of an individual with gross-sectional competent tricuspid AV is depicted (
C
, sample obtained during autopsy). Rectangles (
A, B
) mark areas with translamellar mucoid extracellular matrix accumulation leading to the diagnosis of moderate overall medial degeneration.
10-1055-s-0042-1750408-i210422crc-2.jpg
PMC9296265_01_10-1055-s-0042-1750408-i210422crc-2.jpg
FI210422crc-2
 The histological grading was performed according to the consensus statements on aortic pathology.   Results are displayed in Table 1 and Fig. 2 .