PMC5541759_01
Colonoscopic image of fungating mass in the proximal sigmoid colon.
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F1
Colonoscopy showed a 6 cm, fungating, oozing mass in the proximal sigmoid colon with no evidence of obstruction (Figure 1).
(A) Biopsy of specimen showing inflammatory, necrotic debris, and sevelamer crystals (arrow). (B) Magnified view of sevelamer crystals.
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F2
Acid-fast and periodic acid-Schiff stain highlighted eosinophilic fish-scale crystals consistent with sevelamer deposition (Figure 2).
Follow-up colonoscopy at 3 months showing healthy mucosa throughout the colon.
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F3
After sevelamer was discontinued, repeat colonoscopy at 3 months showed normal pink mucosa with healthy blood vessels throughout the entire colon (Figure 3).