PMC9385684_01
Abdominal computed tomography (CT) on admission shows edematous and thickened walls of the ascending colon (white arrow).
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Abdominal CT showed an edematous and thickened colonic wall (Fig. 1).
Chest CT on the 46th day shows ground-glass opacities in bilateral upper lobes of the lung.
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On the 46th day, the patient's chest X-ray showed infiltration of bilateral upper lung fields, and chest CT showed persistent consolidation limited to the radiation field in the right upper lobe of the lung and new ground-glass opacites in bilateral upper lobes of the lungs (Fig. 2).
Macroscopic evaluation shows pulmonary edema (a), multiple ulcerations (white arrows) of the jejunum (b) and of the colon (c).
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Macroscopic evaluation showed pulmonary edema (Fig. 3a). Multiple ulcerations were observed from the jejunum (Fig. 3b) to the colon (Fig. 3c).
Histopathologic findings of bilateral lungs show diffuse alveolar damage with hyaline membrane formation (black arrow) (hematoxylin-eosin stain, 100 x ) (a). Those of the jejunum show inflammatory infiltration and ulceration (black arrows) (hematoxylin-eosin stain, 40 x ) (b).
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Histologically, bilateral lungs showed diffuse alveolar damage with hyaline membrane formation (Fig. 4a), suggesting the possible diagnosis of immune-related pneumonia. Inflammatory infiltration and ulceration of colonic mucosa were observed (Fig. 4b), suggesting immune-related colitis.