PMC8323404_01
The polypoid perianal lesion.
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At the 5 o'clock position in the left posterolateral region, a polypoid lesion of 25 mm maximum diameter was attached to the distal anal canal wall, with a base which measured approximately 20 mm (Figure 1).
Histological examination revealed a fibroepithelial proliferation with abundant fibrous
stroma and glandular structures (H&E, x40).
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Within the stroma, some glandular structures maintained a round configuration similar to a pericanalicular fibroadenoma, while others had an elongated ductular structure like the intracanalicular pattern of a fibroadenoma (Figure 2).
Glands covered by cuboidal/low columnar epithelial cells resting on a myoepithelial
cell layer (H&E, x100).
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The glands were covered by cuboidal/low columnar epithelial cells without cytologic atypia resting on a myoepithelial cell layer (Figure 3).