PMC5255998_01
A congested glomerulus with red blood cells in the capillary vessels. The glomerular architecture is maintained other than mild vascular hyalinosis (H and E, x40)
IJN-27-78-g001.jpg
PMC5255998_01_IJN-27-78-g001.jpg
F1
INR normalized, a renal biopsy was done which showed the modest matrix expansion associated with vascular hyalinosis, glomerular congestion with RBCs [Figure 1], and diffuse tubular damage with large and occlusive RBC casts in the tubules associated with interstitial hemosiderin laden macrophages suggestive of interstitial hemorrhage [Figure 2]. Immunofluorescence studies were negative.
Extensive and diffuse tubular damage. Also seen are large occlusive red blood cell casts in the tubular lumina. The interstitium shows focal areas of hemosiderin-laden macrophages suggestive of interstitial hemorrhage (arrow) PAS stain (x40)
IJN-27-78-g002.jpg
PMC5255998_01_IJN-27-78-g002.jpg
F2
INR normalized, a renal biopsy was done which showed the modest matrix expansion associated with vascular hyalinosis, glomerular congestion with RBCs [Figure 1], and diffuse tubular damage with large and occlusive RBC casts in the tubules associated with interstitial hemosiderin laden macrophages suggestive of interstitial hemorrhage [Figure 2]. Immunofluorescence studies were negative.