PMC6898721_01
PMC6898721_02
(A) Clinical observations according to the canine inflammatory bowel disease activity index score. A score of 3 or less was considered normal. * indicates the date of each fecal microbiota transplantation (FMT) procedure conducted. Of note, the patient with inflammatory bowel disease (IBD) achieved a normal score from day 42 of FMT throughout the remainder of the observation period. (B) Clinical observations according to the WalthamTM Feces Scoring System. A score of 3.5 or less was considered normal. *indicates the date of each FMT procedure conducted. Of note, the patient with IBD achieved a normal score from day 42 throughout the remainder of the observation period.
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The CIDBAI score improved from 9 to 4, while the WalthamTM score improved from 5 to 2 (Figure 1A and B).
Rarefaction analysis of V3-V4 16S rRNA gene sequences. Rarefaction analysis using a fecal sample from the dog with inflammatory bowel disease (IBD) showed changes in bacterial populations at, before, and after fecal microbiota transplantation (FMT) compared to the healthy donor dog. * indicates the date of each FMT procedure conducted.
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The analysis showed a difference in the proportion of bacterial populations in the feces before FMT, compared to that after FMT and with the donor fecal sample (Figure 2).