PMC2852755_01
A lateral radiograph of the sternum showed an ill-defined osteolytic lesion in the sternum. Periosteal reactions around the lesion were also observed.
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Radiographs showed an osteolytic lesion in the sternum (Figure 1).
Computed tomography (CT) showed an osteolytic lesion that dissolved both anterior and posterior cortex of the body of the sternum.
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Computed tomography (CT) revealed the osteolytic lesion dissolving both anterior and posterior cortices of the body of the sternum (Figure 2).
Magnetic resonance imaging (MRI). The signal intensity of the tumor was low in the sternum on T1-weighted images (A) and high on T2-weighted images (B).
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T2-weighted images (Figure 3). Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia (Figure 4). The greater trochanter of the right femur was tender, but the distal tibia was not, and radiographs showed small and round osteolytic lesions in both places (Figure 5).
Technetium bone scintigraphy reveals increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia.
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T2-weighted images (Figure 3). Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia (Figure 4). The greater trochanter of the right femur was tender, but the distal tibia was not, and radiographs showed small and round osteolytic lesions in both places (Figure 5).
Radiographs show small and round osteolytic lesions (arrows) in the greater trochanter of the right femur (A) and the distal tibia (B).
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T2-weighted images (Figure 3). Technetium bone scintigraphy revealed increased uptakes in the sternum, the greater trochanter of the right femur, and the right distal tibia (Figure 4). The greater trochanter of the right femur was tender, but the distal tibia was not, and radiographs showed small and round osteolytic lesions in both places (Figure 5).
Histopathologic findings. Histopathologic examination reveals a proliferation of histiocytes with an infiltration of eosinophils. These histocytes were positive for S-100 (B), and for CD-1a (C). Original magnification x400.
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Immunohistochemically, these histiocytes were positive for S-100 and CD1a (Figure 6).