PMC7548984_01
Histopathological findings of the liver biopsy specimen. The diffuse proliferation of small lymphocytes was observed with a boundary on liver tissue. (hematoxylin and eosin staining, original, x 4).
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Pathologic examination showed diffuse proliferation of small lymphocytes with a boundary on the liver tissue (Fig. 1) and positive for CD20 and CD79a.
Computed tomography showing bilateral, diffuse, multiple micronodules in a random distribution pattern, consistent with a miliary pattern throughout both lungs.
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Computed tomography of the chest showed innumerable, tiny, well-defined miliary nodules of 1-3 mm diameter in a random distribution pattern, and some of which are distributed in the subpleural (Fig. 2).
(A) A biopsy specimen was obtained from the right middle segment and subjected to histopathological analysis. There are multiple small nodular lesions in pleural area, which are composed of lymphoid cells and scattered interlobular septum of the lung and pleural (hematoxylin and eosin staining, x 4). (B) A biopsy specimen was obtained from the right middle segment and subjected to histopathological analysis. In peribronchovascular area, lymphoid cells found along the bronchovascular bundle involving the mucosa along the bronchial and bronchiolar trees extravascularly. (Left: hematoxylin and eosin staining, x 4. Right: hematoxylin-eosin stain and Elastica van Gieson stain, x 4).
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It scattered the interlobular septum of the lung and pleural (Fig. 3A). In peribronchovascular area (Fig. 3B, hematoxylin-eosin stain and Elastica van Gieson stain), these lymphoid cells found with the bronchovascular bundle, involving submucosa of the bronchiolar trees.
18F-FDG PET imaging. 18F-FDG in the liver lesions in the left medial and right posterior inferior segment are SUVmax of 8.7 and 5.1. The SUVmax in lymph node regions of paraaortic left infra-clavicular and mesenteric were >3.3.
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The SUVmax in lymph node regions of paraaortic left infra-clavicular and mesenteric were >3.3 (Fig. 4).