PMC5573443_01
PMC5573443_02
Unified Parkinson's Disease Rating Scale III evaluation before, during, and after therapy with deferiprone.
fneur-08-00385-g001.jpg
PMC5573443_02_fneur-08-00385-g001.jpg
F1
III had already been performed, during and after the chelation therapy. In the Figure 1, the worsening and also improvement of the patient status can be clearly seen.
(A) T1-weighted axial image shows linear hypointensity at the level of cerebral peduncles in the substantia nigra within a mild area of hyperintensity. At the same level in the images (B,C), both T2-weighted, a striking hypointensity can be seen in both substantiae nigrae. A more cranial axial T2-weighted section shows a marked bilateral hypointensity of the globus pallidus (D,E).
fneur-08-00385-g002.jpg
PMC5573443_02_fneur-08-00385-g002.jpg
F2
T2-weighted images, indicating the existence of ferromagnetic substances and a cyst in the pineal gland (Figure 2). Two subsequent MRIs were performed in 2015 and in 2016, and they showed an increase in the ferromagnetic deposits in the abovementioned areas.