PMC3902556_01
Video-assisted thoracoscopic image of the posterior mediastinal mass
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F1
Inspection of the left hemithorax revealed a 2.5 cm mass in the left paravertebral area near the apex of the lung [Figure 1].
(a) Submucosal mass in hepatic flexure (b) Endoscopic appearance of the operative field after excision
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F2
After a 9 month of follow-up, screening colonoscopy revealed a submucosal mass measuring approximately 1 cm in diameter [Figure 2a]. The mass was excised en bloc by endoscopic mucosal resection (EMR) using a snare [Figure 2b].
(a) Tumour with granular cells, beneath the colonic surface epithelium (H and E x200), (b) Positive for Periodic acid-Schiff (PAS x200), (c) Diffuse and strong S-100 protein positivity in the tumour (immunohistochemical staining, S-100 protein)
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F3
H and E-stained sections of the lesion revealed a tumour, which was located in the submucosa and partly in the mucosa [Figure 3a]. The tumour cells with abundant granular eosinophilic cytoplasm were containing acidophilic Periodic acid-Schiff (PAS)-positive diastase-resistant granules [Figure 3b]. Immunohistochemical analysis revealed diffuse expression of S100 protein [Figure 3c].