PMC5220424_01
CT scan of the patient, displaying the rapid rate of growth of the meningioma: (a) axial view December 2012; (b) axial view December 2014; (c) coronal view 2012; (d) coronal view 2014.
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After taking CT imaging of the brain, a 6.3 x 5.7 x 6 cm mass was found in the right frontal lobe (Figures 1(b) and 1(d)). Previous CT without contrast performed two years previously (December 2012) because of increasingly severe headaches did not show a mass, though in retrospect it did show a focal area of density where the meningioma would later present (see Figures 1(a), and 1(c)).
Histology of the tumor: (a) low magnification (x100) showing typical features of meningioma; (b) high magnification (x400) showing some evidence of nuclear atypia; (c) immunohistochemical staining showing the tumor to be progesterone receptor positive (x200 magnification).
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Histological examination of the specimen was consistent with grade II meningioma with atypia (Figures 2(a) and 2(b)). Progesterone staining was positive (Figure 2(c)).