PMC4745613_01
PMC4745613_02
(a) Patient 2 at time of initial EGD wherein the esophageal squamous epithelium contains a peak density of 20 eosinophils per high power field. (b and c) Esophageal biopsies taken after treatment with a proton pump inhibitor and dietary modification with (b) representing the distal esophagus with a peak density of 5 intraepithelial eosinophils per hpf and (c) representing the proximal esophagus with a peak density of 3 intraepithelial eosinophils per hpf.
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fig1
Before coming to the University of Utah SSc clinic, she had EGD which noted an esophagitis with a peak density of 20 intraepithelial eosinophils/high powered field (hpf) (Figure 1(a)). Her repeat EGD reported persistent chronic esophagitis while the corresponding histopathology showed a peak density of 3 intraepithelial eosinophils/hpf within the proximal esophagus and a peak density of 5 intraepithelial eosinophils/hpf within the distal esophagus (Figures 1(b) and 1(c)).
Esophageal tissue stained for ANA.
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fig2
An immunofluorescence for ANA sent on this esophagus biopsy specimen was positive (Figure 2).