PMC4716750_01
PET-CT of the patient.. Abbreviations: A, anterior; CT, computed tomography; PET, positron emission tomography; P, posterior; S, superior; MIP, multum in parvo.
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Computed tomography (CT) scan of chest and abdomen revealed hepatosplenomegaly. 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning showed increased FDG avidity involving the thoracic vertebrae 1 and 8, the left ribs 4 and 6, the thoracic spine, sacrum, bilateral ilium, left pubis, and femur, suggesting lymphoma involvement (Figure 1).
Biopsy of soft tissue lesions.. Notes: (A) ALK staining, original magnification: x200; (B) CD30 staining, original magnification: x200.. Abbreviations: ALK, anaplastic lymphoma kinase; CD, cluster of differentiation.
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These cells were positive for ALK-1 (Figure 2A), CD30 (Figure 2B), leukocyte common antigen, CD3, CD4, and CD8, as well as being negative for epithelial membrane antigen and pan-cytokeratin.