PMC2999720_01
An ulcerated lesion surrounding the urethral meatus
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A genital exam demonstrated an ulcerated lesion partially exposed on the glans penis caused by poor retractability of the foreskin (Figures 1 and 2); the scrotum and prostate exams were normal.
A penile lesion after dorsal incision of the foreshaft
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A genital exam demonstrated an ulcerated lesion partially exposed on the glans penis caused by poor retractability of the foreskin (Figures 1 and 2); the scrotum and prostate exams were normal.
The yeast forms can be visualized with periodic acid-Schiff (PAS) as round or oval-shaped structures with single or multiple buds (arrows); 400X, zoom 1.5X.
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A penile biopsy was positive for PCM (Figures 3 and 4).
The yeasts are better visualized using silver impregnation (Gomori-Grocott), confirming the diagnosis of PCM (arrows); 400X, zoom 1.5X.
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A penile biopsy was positive for PCM (Figures 3 and 4).
PMC2999720_02
Prostate tissue with chronic granulomatous inflammation with multinucleated giant cells; 400X, zoom 1.5X.
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With the suspicion of genitourinary PCM, a US-guided prostate biopsy was performed, which revealed granulomatous chronic prostatitis with fungal structures consistent with PCM (Figures 5 and 6).
Gomori-Grocott-stained preparations showing the fungal cells (arrows), confirming the diagnosis of prostatic PCM; 400X, zoom 1.5X.
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With the suspicion of genitourinary PCM, a US-guided prostate biopsy was performed, which revealed granulomatous chronic prostatitis with fungal structures consistent with PCM (Figures 5 and 6).