PMC9058116_01
Ulceration with a stalactite appearance at the distal end of the index finger.
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F1
Physical examination revealed a well-demarcated violescent ulceration with a stalactite appearance at the distal end of the index finger (Figure 1). The patient was treated with ciprofloxacin hydrochloride (at a dose of 1.5 g three times daily for 20 days), and her lesion showed substantial improvement (Supplementary Figure 1).
Biopsy of the lesion showed dense infiltration of multinuclear giant cells (red arrow), histiocytes (yellow arrow), and lymphocytes (blue arrow) in the dermis (hematoxylin and eosin stain, x400).
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F2
Biopsy of the lesion showed a dense infiltration of multinucleated giant cells, histiocytes, and lymphocytes in the dermis (Figure 2).
Next-generation sequencing and metagenomics analysis. Proteus mirabilis specific reads and its nucleotide position along the Proteus mirabilis genome.
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F3
NGS result showed that P. mirabilis had 306 unique sequence reads, covering 33.49% of the nucleotide sequences (Figure 3).