PMC5892316_01
a Color fundus photograph shows optic disc and retinochoroidal coloboma (white arrow) and subretinal hemorrhage (white arrowhead) c-e The horizontal SD-OCT section through the indicated lesion (b, white arrow) was shown in order. c The SD-OCT shows elevated pigment epithelium detachment (yellow asterisk) and "double-layer sign" (white arrowheads) accompanied with serous detachment. d The SD-OCT shows choroidal excavation (yellow arrowheads) and intrachoroidal cavitation (white arrow) with serous detachment. There is an abnormality in the retinal pigment epithelium (white arrowhead) corresponding to point dye leakages on indocyanine green angiography (ICGA) (f, right panel, yellow arrowheads). e The SD-OCT shows intrachoroidal cavitation (yellow asterisk) with serous detachment. f, g Middle phase (f, left panel) and late phase (g, left panel) fluorescein angiography shows dye leakage from PCV. Middle phase (f, right panel) and late phase (g, right panel) ICGA shows a polypoidal lesion (yellow arrow heads). Hyporefractive lesion of ICGA (white arrowheads) represents the area of choroidal excavation
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F1
Fundus examination of her left eye revealed optic disc and retinochoroidal colobomas associated with subretinal hemorrhage around the optic disc (Fig. 1a, b) and macular serous retinal detachment (SRD). Optical coherence tomography (OCT) confirmed macular SRD (Fig. 1c-e) and a sharply elevated retinal pigment epithelial detachment connecting with "the double-layer sign," which represents a branched vascular membrane above the retinal pigment epithelium (RPE) (Fig. 1c). OCT also revealed a peripapillary choroidal cavitation (PCC) at the temporal margin of the optic disc coloboma (Fig. 1d, e). Fluorescein angiography showed hyperfluorescent dye leakage, and indocyanine green angiography revealed polypoidal lesions (Fig. 1f, g); PCV was diagnosed.
a Color fundus photograph shows the regression of subretinal hemorrhage 1 year after treatment. b, c The SD-OCT shows the resolution of subretinal fluid at the macula and the PCV lesion.
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F2
One month later, OCT revealed completely resolved SRD (Fig. 2b, c).