PMC9649302_01
(a): IHC (x10), (b): FISH (x10), and (c): FISH (x100); a fluorescence in situ hybridization (FISH) technique for the detection of the t (9; 22) (q34; q11) reciprocal translocation was performed in samples with mast cell infiltration and was negative.
CRIHEM2022-7251658.001.jpg
PMC9649302_01_CRIHEM2022-7251658.001.jpg
fig1
BM study with a fluorescence in situ hybridization (FISH) technique for the detection of the t (9; 22) (q34; q11) reciprocal translocation was performed in samples with mast cell infiltration and was negative (Figure 1). Bone marrow samples from the initial diagnosis of CML were not available to investigate the presence of mast cell infiltration.