PMC3318779_01
Multiple, erythematous, lesions of varying size present on the skin of the left lower extremity.
CRIM2012-989104.001.jpg
PMC3318779_01_CRIM2012-989104.001.jpg
fig1
Physical examination was remarkable for multiple, shiny, immobile, erythematous, follicular papules ranging from 1 to 5 millimeters in size on his bilateral lower extremities (Figures 1 and 2).
Erythematous follicular papules sometimes coalescing and forming nodules on the patient's right lower extremity.
CRIM2012-989104.002.jpg
PMC3318779_01_CRIM2012-989104.002.jpg
fig2
Physical examination was remarkable for multiple, shiny, immobile, erythematous, follicular papules ranging from 1 to 5 millimeters in size on his bilateral lower extremities (Figures 1 and 2).
Hematoxylin and eosin staining of a 4 millimeter papule on the right lower extremity. Note the glandular structure of metastatic adenocarcinoma (arrow) with a desmoplastic reaction in surrounding tissue of the dermis (arrowhead).
CRIM2012-989104.003.jpg
PMC3318779_01_CRIM2012-989104.003.jpg
fig3
Histopathologic evaluation of the biopsy revealed the presence of glandular structures suggesting metastatic adenocarcinoma consistent with a primary colon cancer, with a desmoplastic reaction in surrounding tissue of the dermis (Figure 3).