PMC4745326_01
(a) Portable chest X-ray showing bilateral lung opacities with relative sparing of the right upper lobe and left pleural effusions. (b) CT scan of chest showing multifocal and bilateral, predominantly peripheral airspace opacities.
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fig1
Chest X-ray revealed bilateral lung opacities with relative sparing of the right upper lobe and left pleural effusions (Figure 1(a)). Computed tomography (CT) scan showed multifocal, bilateral, predominantly peripheral airspace opacities (Figure 1(b)).
(a) Lung parenchyma with intra-alveolar hemorrhage, multiple vacuoles, macrophages, and dilated capillaries (40X). (b) Lung parenchyma with dilated capillaries and nonrefractile vacuole-like structures (20X).
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fig2
A wedge biopsy tissue of the right lower lobe revealed intra-alveolar hemorrhage with dilated capillaries containing nonrefractile vacuole-like structures suggestive of deposition of lipoid material (Figures 2(a) and 2(b)).
PMC4745326_02
(a) Lung parenchyma with multiple vacuoles and dilated capillaries (40X). (b) Lung parenchyma with dilated capillaries and nonrefractile vacuole-like structures and histiocytic reaction (40X).
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fig3
The biopsy tissue showed granulomatous inflammation associated with silicone particles in the lung tissue (Figures 3(a) and 3(b)).