PMC6507115_01
Hematoxylin and eosin stain. Anatomopathological examination of the subcutaneous nodule in the right flank. High-grade solid malignant neoplasm infiltrating the fibroadipose tissue, revealing squamous differentiation through multiple foci of keratinization.
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At this time, a biopsy in one of the subcutaneous implants located in the right flank was performed, confirming metastasis from esophageal squamous cell carcinoma (Figure 1) and immunohistochemistry (IHQ) was also performed, whose morphological findings were compatible with keratinizing epidermoid carcinoma infiltrating adipose tissue positive for p63/4A4 and cytokeratin cocktail.
Subcutaneous metastasis on the right hemithorax and flank.
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fig2
A tomography was performed, and it showed a 38 mm right paravertebral expansive lesion on the L5 level, infiltrating the psoas muscle, lesions in soft parts of the left paramedian dorsal region, worsening of the armpit and right flank subcutaneous nodules (Figures 2 and 3), and multiple lymph node, bone, and pulmonary metastases.
Subcutaneous metastasis in the right armpit region.
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fig3
A tomography was performed, and it showed a 38 mm right paravertebral expansive lesion on the L5 level, infiltrating the psoas muscle, lesions in soft parts of the left paramedian dorsal region, worsening of the armpit and right flank subcutaneous nodules (Figures 2 and 3), and multiple lymph node, bone, and pulmonary metastases.