PMC6180351_01
Hyperplasia of bone marrow, decreased granulocyte ratio, increased erythroid proportion, containing 12% unclassified cells. Bar: 100 mum.
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PMC6180351_01_1414-431X-bjmbr-51-11-e6278-gf001.jpg
f01
The results of the examinations of the bone marrow aspirate and biopsy are shown in Figures 1- 3.
Pathologic and immunohistochemical analysis showing hematopoietic tissue between bone marrow scattered mass. Specific cells with patchy distribution, in which cells ranged in size from small to medium, nuclei were pale, enlarged, and irregular including thin karyotheca, inconspicuous nucleoli, partly visible nucleoli, and interstitial fibrous tissue hyperplasia. Atypical cells CD2, CD3, CD5, CD7, and TIA-1 were found positive, CD20, CD79a, and CD117 were found negative, and MPO myeloid cells were found positive. Bar: 10 muM. Diagnosis: Lesions conformed to abnormal proliferation of bone marrow T lymphocytes. The case was considered to be T-cell lymphoma involving the bone marrow.
1414-431X-bjmbr-51-11-e6278-gf003.jpg
PMC6180351_01_1414-431X-bjmbr-51-11-e6278-gf003.jpg
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The results of the examinations of the bone marrow aspirate and biopsy are shown in Figures 1- 3.