PMC6494960_01
Test for attentional performance during the course of the disease.
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Moreover, he suffered from attention and concentration deficits (Figure 1, t0), inner restlessness, signs of derealization (with altered, slowed, and delayed perception of his environment), and severe dizziness (still comparable with having drunk five beers). The neuropsychological test of attentional performances showed severe deficits in alertness, divided attention, set shifting, and working memory (Figure 1, t0). Neuropsychological testing showed no relevant improvement (Figure 1, t1). Neuropsychological testing revealed an improvement in alertness, mental flexibility, and working memory [Figure 1, t2 (before) versus t3 (after) the second steroid pulse treatment].
T2w fluid-attenuated inversion recovery (FLAIR) cerebral magnetic resonance imaging (cMRI) shows multiple disseminated dotted bilateral periventricular to subcortical white matter lesions. Shown are images of the first cMRI performed 6 months after symptom exacerbation in November 2016.
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In the cMRI, multiple diffuse periventricular white matter lesions were apparent in repeated examinations throughout the course (Figure 2). Neuropsychological testing revealed an improvement in alertness, mental flexibility, and working memory [Figure 1, t2 (before) versus t3 (after) the second steroid pulse treatment].