PMC9468333_01
MRI result showing long T1 [(A), arrow] and slightly longer T2 [(B), arrow] signals with a diameter of 1.5 cm in the S6 segment of the liver. Diffusion-weighted imaging result showing a high signal [(C), arrow]. Enhanced scanning result showing slight circular enhancement in the arterial phase [(D), arrow] and continuous circular enhancement in the portal venous phase [(E), arrow] and delayed phase [(F), arrow].
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The MRI ( Figure 1 ) result showed that the liver was normal in size and shape, with a diameter of 1.5-cm-long
18F-FDG PET/CT image showing no other abnormal hypermetabolic lesion except in the liver [(A), MIP, arrow]. The liver lesion could not be clearly displayed in the background of fatty liver on CT [(B), CT image, arrow]. The CT mean value of the liver was about 37 HU. The lesion showed a high uptake of 18F-FDG [(C), PET image; arrow], and the SUVmax is 4.0. It was finally confirmed as Castleman's disease by postoperative pathology [(D); H&E, x200].
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The MRI result suggested the possibility of primary liver malignant tumor or liver metastasis.18F-FDG PET/CT ( Figures 2A-C ) showed no other abnormal hypermetabolic lesion except the liver. The postoperative pathology showed that the size of the liver lesion was about 1.7 cm x 1.5 cm x 1.5 cm, and HE staining ( Figure 2D ) showed lymphoproliferative lesions, including multiple follicular structures, some follicular germinal centers, marginal zone cell proliferation, mutual encirclement and fusion, and proliferation of small vessels with hyaline degeneration of the walls in the follicles.