PMC5646291_01
(a and c) Large atypical lymphoid cells with one to more nuclei, prominent nucleoli, and abundant cytoplasm consistent with RS cells and Hodgkin cells on the hematoxylin and eosin stain. (b and d) The large atypical cells are negative for PAX5 expression.
CRIHEM2017-7531729.001.jpg
PMC5646291_02_CRIHEM2017-7531729.001.jpg
fig1
The majority of the large cells were mononucleated cells with prominent large cherry red nucleoli and moderate to abundant eosinophilic cytoplasm, consistent with Hodgkin cells (Figure 1(c)). These large cells were positive for CD30, CD15 (subset), CD79a (small subset), and MUM1 but were negative for CD20, CD45, OCT2, PAX5 (Figure 1(d)), CD2, CD3, CD4, CD5, CD7 CD8, granzyme-B, perforin, and ALK1.
PMC5646291_02
(a and c) Large atypical lymphoid cells with one to more nuclei, prominent nucleoli, and abundant cytoplasm consistent with RS cells and Hodgkin cells on the hematoxylin and eosin stain. (b and d) The large atypical cells are negative for PAX5 expression.
CRIHEM2017-7531729.001.jpg
PMC5646291_02_CRIHEM2017-7531729.001.jpg
fig1
The majority of the large cells were mononucleated cells with prominent large cherry red nucleoli and moderate to abundant eosinophilic cytoplasm, consistent with Hodgkin cells (Figure 1(c)). These large cells were positive for CD30, CD15 (subset), CD79a (small subset), and MUM1 but were negative for CD20, CD45, OCT2, PAX5 (Figure 1(d)), CD2, CD3, CD4, CD5, CD7 CD8, granzyme-B, perforin, and ALK1.