PMC5343240_01
The 24-hour and twelve-lead electrocardiograms on admission. The 24-hour electrocardiogram shows a ventricular arrhythmia persisting for more than five minutes, and the twelve-lead electrocardiogram on admission shows incessant ventricular tachycardia.
CRIHEM2017-4027908.001.jpg
PMC5343240_01_CRIHEM2017-4027908.001.jpg
fig1
His electrocardiogram showed nonsustained VT, which developed into VT storms even after starting amiodarone (Figure 1).
Electrocardiogram on the 22nd day after dasatinib retreatment. Potentially fatal ventricular arrhythmias have been replaced by atrial flutter.
CRIHEM2017-4027908.002.jpg
PMC5343240_01_CRIHEM2017-4027908.002.jpg
fig2
After being withdrawn for 22 days, dasatinib was rechallenged, and we could continue without the appearance of nonsustained VT or the prolongation of QTc intervals (Figures 2 and 3).
Clinical course before and after dasatinib treatment. VT, ventricular tachycardia; PSL, prednisolone; CHR, complete hematological response.
CRIHEM2017-4027908.003.jpg
PMC5343240_01_CRIHEM2017-4027908.003.jpg
fig3
After being withdrawn for 22 days, dasatinib was rechallenged, and we could continue without the appearance of nonsustained VT or the prolongation of QTc intervals (Figures 2 and 3).