PMC9469016_01
(A, B) Abdominal enhanced computed tomography imaging representing the huge tumor between the right lobe of the retroperitoneal liver and the right kidney. (C) A macroscopic image of the post-section cystic pheochromocytoma. (D) Excised tumor, measuring 20 x 15 x 10 cm.
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Abdominal enhanced CT revealed obvious compression atrophy of the liver and a 20 cm x 13 cm mixture of cystic and solid lesions between the right lobe of the retroperitoneal liver and the right kidney ( Figures 1A, B ). The resection of the giant right adrenal pheochromocytoma was completed through a right subcostal incision under general anesthesia ( Figure 1C ). Pathological examination of the surgical specimen indicated a necrotic change measuring 20 x 15 x 10 cm and weighing 2,240 g located in the retroperitoneum and right adrenal gland ( Figure 1D ).
H&E staining in (A) x10 view and (B) x40 view. (C, D) CD56 staining immunohistochemistry of the tumor.
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Hematoxylin-eosin (H&E) staining showed a well-circumscribed tumor surrounded by a fibrous capsule ( Figures 2A, B ). Immunohistochemistry showed marked pleomorphism within a few tumor cells, CD56(+), CgA (+), Syn(+), CK (Pan)(-), MART-1(-), inhibitA(-), S-100(+), INI1(+), Desmin(-), and Myogenin(-) ( Figures 2C, D ).