PMC9815948_01
Time course of antibiotic exposure and clinical symptoms.
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PMC9815948_01_10-1055-a-1857-5062-i1474-0001.jpg
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The patient was discharged on day 14 after DRESS development, skin rash continued for another 2-3 weeks and liver function was normalized 5 weeks after discharge ( Fig. 1 ). Interestingly, strong reactivity to all penicillin-related antibiotics (penicillin, ampicillin, amoxycillin; ( Table 1 , Fig. 1 ), but not to cephalosporins was detected, indicating T-cell interaction with penicillin-specific side chains. 
PMC9815948_02