PMC5312206_01
Clinical picture of the self-resolving lesions. A. Papulo-
nodular lesion located on the palm of the right hand. B.
Papulo-nodular lesion, ulcerated at its center, located on right hand
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The papules, located mainly on palms but also on legs and gluteal area, became ulcerated and tend to self-resolve within some weeks, leaving a scar whilst new self-resolving lesions appeared (Figure 1).
Histopathologic findings. A. View of dense infiltrate of
lymphocytes in the papillary dermis, the reticular dermis and the
subcutaneous tissue from biopsy taken from the hand. (Hematoxylin &
eosin x40). B. Detailed image of the infiltrate composed of
small, medium and large atypical lymphocytes. (Hematoxylin & eosin
x100). C. Immunohistochemical findings with CD4+ T cells
(Hematoxylin & eosin x20). D. Immunohistochemical findings
with groups of CD30+ cells (Hematoxylin & eosin x100)
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Immunohistochemistry was CD3+, CD43+ and CD4+ with groups of positive CD30 cells (Figure 2).
Clinical picture of the persistent lesions. A. Large ulcerative
plaque of 3cm on the leg accompanied by other smaller papulo- necrotic
lesions. B. Observe the growing and persistence of the same
lesions.
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One year later the lesions became persistent and did not disappear spontaneously (Figure 3).