PMC6927290_01
Placental Histopathology (A) Very scant intervillusitis (arrow) composed of granulocytes and lymphocytes between immature chorionic villi. (B) Mural thrombus formation (arrow) in large chorionic plate vessel, with scant mononuclear infiltrate (B and T lymphocytes with histiocytes) in vessel wall and deep thrombus. (C) Umbilical vein and adjacent cord, demonstrating lack of inflammation or necrosis. (D) Same field as (C), immunohistochemical staining for Treponema pallidum demonstrating innumerable, large, often bent spirochetes (arrow). Magnifications as indicated by scale bars. There was no plasma cell deciduitis.
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F1
Placental pathology showed innumerable spirochetes but a lack of inflammation or necrosis (Figure 1).
Long bone radiographic findings of a preterm infant with symptomatic congenital syphilis. (A) Sclerotic bands of the metaphyses (arrow). (B) Serrated epiphyseal plates (arrow).
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F2
Long bone x-rays revealed sclerotic bands along the metaphyses and serrated epiphyseal plates (Figure 2).