PMC8426056_01
Unenhanced computed tomography scan (a) of the abdomen showing a unilocular left adrenal cyst, without wall's enhancement after contrast injection (b).
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Spontaneous density was 22 Hounsfield unit (HU) (Figure 1(a)), and absolute washout reached 50%. The wall of this lesion did not enhance after contrast injection, and calcification was detected (Figure 1(b)).
Histological study of the lesion: (a) a cystic space lined by flattened endothelial cells filled with blood (star) associated to a proliferation of well-defined clear cells (arrow) (H&Ex100). (b) Alveolar disposition of the clear cells (circle) (H&Ex200). (c) Adrenocortical adenoma (H&Ex400).
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Histological examination of the different specimens showed a cystic cavity with a fibrous wall and constituted of multilocular spaces lined by endothelial cells and filled with red blood cells (Figure 2(a) (star)). A proliferation of well-defined clear cells was found at the rim of this lesion (Figure 2(a) (arrow)) arranged in an alveolar pattern (Figure 2(b)) without cytonuclear atypia (Figure 2(c)).