PMC9639856_01
Cytokine monitoring after CART infusion. CART, chimeric antigen receptor T-cell; IL, interleukin; TNF, tumor necrosis factor; CRP, C-reactive protein.
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Cytokine monitoring after infusion of CART is shown in  Figure 1 .
Timeline of treatment and efficacy. *multiply: six courses of alternative therapy with Hyper-CVAD-A (cyclophosphamide, vindesine, doxorubicin, and dexamethasone), MAVP (methotrexate, cytarabine, vindesine, and dexamethasone).
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The treatment regimen of the patient is depicted in  Figure 2 .
CART cell expansion in vivo. CART, chimeric antigen receptor T-cell.
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CART cells were monitored by reverse transcription polymerase chain reaction ( Figure 3 ). CART cells reached their first peak 6 d after infusion and then dropped.