PMC3870129_01
Computed tomography scan of the cervical showed a right cervical lymphadenopathy measuring 3 x 3 cm.
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Computerized tomography scan of cervical showed right cervical lymphadenopathy (Figure 1).
Microscopic findings of lymph node biopsy revealing (a) a preserved lymph node architecture with multiple lymphoid follicles, with or without hyalinized arteriolar (HESx40) and (b) typical Reed-Sternberg cells in the interfollicular.
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The Interfollicular tissue appears homogenized with a polymorphous population of cells composed of lymphocytes, histiocytes, and typical Reed-Sternberg cells (Figure 2).
Immunohistochemical analysis showing positive staining of the Reed-Sternberg cells for (a) CD15 and (b) CD30.
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In the immunohistochemical study, typical Reed-Sternberg cells were positive for CD15 and CD30 (Figure 3).
The assessment computed tomography scan of cervical after 4 cycles of chemotherapy showed a complete response.
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Evaluation by Cheson criteria after 4 courses of chemotherapy was in favor of a complete response (Figure 4).