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Brain CT before and after endoscopic third ventriculostomy and left EVD. (A) Brain CT scan on admission showing severe hydrocephalus and interstitial brain edema; (B) brain CT scan after endoscopic third ventriculostomy and left EVD in our hospital; (C) brain CT about one month after endoscopic third ventriculostomy and left EVD showing improvement of interstitial cerebral edema, but hydrocephalus was still present; (D) brain CT after a new right EVD was placed due to deterioration of intracranial Myroides odoratimimus infection while hydrocephalus was significantly better than before. Red arrow: catheter of EVD.
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Babinski sign. Brain computed tomography (CT) scan revealed severe hydrocephalus and interstitial brain edema (Figure 1A). Ltd) was initiated after the surgery, and the patient was successfully weaned off the ventilator, although brain CT scan still suggested hydrocephalus and interstitial brain edema (Figure 1B).  A brain CT scan (Figure 1C) revealed improvement in interstitial cerebral edema, although hydrocephalus persisted, and CSF drainage from the EVD tube exceeded 200 mL per day, necessitating prolonged retention of the EVD. Table 1), and the minimum inhibitory concentration (MIC) of tigecycline against M. odoratimimus was 0.5 mg/L. Consequently, the patient received intracerebroventricular (ICV) administration of 2mg tigecycline q12h, which was diluted in saline up to a volume of 5mL and injected through the EVD catheter within two minutes after removing an equivalent volume of CSF through EVD. The EVD catheter was closed for two hours after each dose of injection, and a new right EVD was placed as well (Figure 1D). 
Protein and glucose in CSF during hospitalization.
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Brain MRI revealed partial blood accumulation in the right thalamus associated with mild hydrocephalus. (A) T1-weighted image; (B) T2-weighted image; (C) diffusion-weighted image (DWI); (D) flair image.
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Brain magnetic resonance imaging (MRI) revealed the presence of partial blood accumulation in the right thalamus, along with mild hydrocephalus (Figure 3).
Brain CT on the first day and the 12th day after removal of EVD showing deterioration of hydrocephalus. (A) Brain CT on the first day after removal of EVD showing mild hydrocephalus; (B) brain CT on the 12th day after removal of EVD suggesting aggravation of hydrocephalus.
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CSF sampling revealed no recurrence of intracranial infection 12 days after antibiotic discontinuation, while brain CT scanning demonstrated a deterioration of hydrocephalus (Figure 4). Consequently, a ventriculoperitoneal (VP) shunt was inserted on the 92nd day of hospitalization, and the patient was weaned off the ventilator.