PMC4531652_01
The chest PA shows a round mass with central low density in the right lower lobe.
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The chest radiograph obtained at the time of admission showed a round mass in the right lower lobe (Figure 1).
The chest CT shows a large cystic mass with central low density and no mediastinal or hilar lymphadenopathy.
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The chest CT scan documented a slightly increased size of the mass, with more increased extent of the central low density compared with the previous chest CT and no mediastinal or hilar lymphadenopathy (Figure 2).
Microscopic views. The epithelial component shows poorly differentiated squamous cell carcinoma (A) and the mesenchymal component shows chondrosarcoma (B). (H & E stain, x 400)
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The carcinomatous components consisted of poorly differentiated squamous cell carcinoma and the sarcomatous components were considered chondroid sarcoma in the light of microscopic findings (Figure 3).
Immunohistochemical stainings. The poorly differentiated squamous cell carcinoma shows focal positive for epithelial membrane antigen (A). The chondrosarcoma shows positive for vimentin (B). (x 400)
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Light microscopic immunohistochemical analysis showed that the tumor cells in the carcinomatous component reacted with anti-epithelial membrane antigen (EMA) antibody and the tumor cells in the sarcomatous component reacted with anti-vimentin antibody (Figure 4).