PMC9094131_01
Explanted Liver from Case 3 (H&E stain). A (low power) Lobules (short arrows) show a significant panlobular inflammatory infiltrate with lobular architectural disarray and prominent hepatocyte drop-out. A portal tract on the right (long arrows) reveals an inflammatory infiltrate with interface activity. No bile duct injury is seen. There is no evidence of cirrhosis. B (high power) The lobular inflammatory infiltrate (long arrows) consists predominantly of lymphocytes with plasma cells. Cholestasis (short arrow) is also noted
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Fig2
Explant histology showed panlobular hepatitis with regeneration and massive necrosis; no evidence of cirrhosis or fatty liver (Fig. 2).