PMC8683450_01
PMC8683450_02
Sister Mary-Joseph nodule aspect on the admission
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F1
Clinical findings: on admission, we found on physical examination, an ulcero-budding mass (Figure 1), which appeared ten months after the treatment of peritonitis is which manifested in the beginning as a hard mass of 3 cm without inflammatory signs insight and which changed character after three months becoming fixed to the deep planes and measuring six cm, with inflammatory signs.
CT-scan of the abdomen; this image shows an umbilical mass
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F2
An abdominal-pelvic computed tomography (Figure 2) was performed, objectifying the presence of: a urachal-cyst that manifested like an oblong structure, extending from the umbilicus to the dome of the urinary bladder measuring 68 * 18 mm.
microphotography at low magnification shows the presence of a carcinomatous proliferation in the dermis, (HE; 10X)
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F3
The histological assessments (Figure 3, Figure 4, Figure 5) of the resectioned parts retained the diagnosis of NSMJ with: for the bladder: no tumor proliferation, chronic inflammatory reshaping of the bladder mucosa; for segmental colectomy of the sigmoid: a well-differentiated and infiltrating adenocarcinoma of 2 * 2.5 * 4 cm, exceeding the sub-serous with a perforated wall, the limits of peripheral surgical resection are healthy (>4 cm), absence of vascular emboli or peri-nerve infiltration, lymph node curage 13 N-/13 N, tumor classified Pt4N0Mx; for the umbilical resection: skin localization of a well-differentiated adenocarcinoma.
microphotography shows that the carcinomatous proliferation in the dermis is identical to those found in the colonic tumor, (HE; 40X)
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F4
The histological assessments (Figure 3, Figure 4, Figure 5) of the resectioned parts retained the diagnosis of NSMJ with: for the bladder: no tumor proliferation, chronic inflammatory reshaping of the bladder mucosa; for segmental colectomy of the sigmoid: a well-differentiated and infiltrating adenocarcinoma of 2 * 2.5 * 4 cm, exceeding the sub-serous with a perforated wall, the limits of peripheral surgical resection are healthy (>4 cm), absence of vascular emboli or peri-nerve infiltration, lymph node curage 13 N-/13 N, tumor classified Pt4N0Mx; for the umbilical resection: skin localization of a well-differentiated adenocarcinoma.
microphotography of the colonic tumor, showing infiltration of the colonic wall by a well-differentiated adenocarcinoma, (HE; 100X)
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F5
The histological assessments (Figure 3, Figure 4, Figure 5) of the resectioned parts retained the diagnosis of NSMJ with: for the bladder: no tumor proliferation, chronic inflammatory reshaping of the bladder mucosa; for segmental colectomy of the sigmoid: a well-differentiated and infiltrating adenocarcinoma of 2 * 2.5 * 4 cm, exceeding the sub-serous with a perforated wall, the limits of peripheral surgical resection are healthy (>4 cm), absence of vascular emboli or peri-nerve infiltration, lymph node curage 13 N-/13 N, tumor classified Pt4N0Mx; for the umbilical resection: skin localization of a well-differentiated adenocarcinoma.