PMC4356044_01
A, Surgical lung biopsy demonstrating increased presence of inflammatory cells along with cavitary and cystic changes. B, Lung Biopsy with CD1a immunostaining demonstrating the presence of increased Langerhans cells.
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Her lung specimens revealed multiple nodules composed of Langerhans cells with mixed inflammatory cells, cavitation and adjacent cystic changes (Fig. 1A). CD1a immunostaining identified the presence of increased Langerhans cells (Fig. 1B).
Temporal relationship of the trend of right ventricular systolic pressure (RVSP) values derived from serial echocardiography (2004-2014) with the use of pulmonary vasomodulatory therapies.
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Following drug initiation, a sharp reduction in RVSP, lessening of tricuspid regurgitation, improvement in RIMP to 0.32, and reduction in her dyspnea severity to NHYA Class II was observed (therapeutic events summarized in Fig. 2).