PMC5127220_01
MRI images in coronal (a), sagittal (b) and axial plane (c) demonstrating the area of the tumor where the voxel of the performed MRS study (d) was obtained.
jocmr-09-074-g001.jpg
PMC5127220_01_jocmr-09-074-g001.jpg
F1
MRI examination, an enhancing right parasagittal brain lesion with significant edema was recognized. MRS examination raised the suspicion of glioma based on the metabolic profile at the center of the tumor which indicated high ratio of choline to N-acetylaspartate (Chol/NAA) (Figs. 1, 2).
1H-MRS of the tumor area (left) showing the high Chol/NAA ratio in comparison to the normal MRS findings of the opposed normal brain tissue (right).
jocmr-09-074-g002.jpg
PMC5127220_01_jocmr-09-074-g002.jpg
F2
MRI examination, an enhancing right parasagittal brain lesion with significant edema was recognized. MRS examination raised the suspicion of glioma based on the metabolic profile at the center of the tumor which indicated high ratio of choline to N-acetylaspartate (Chol/NAA) (Figs. 1, 2).
Axial images of the performed brain SPECT with technetium-99m (Tc99m) demonstrating high standardized uptake value (SUV).
jocmr-09-074-g003.jpg
PMC5127220_01_jocmr-09-074-g003.jpg
F3
The SPECT examination indicated intense and homogenous uptake of the radiopharmaceutical, with notably high standardized uptake value (SUV), supporting the diagnosis of meningioma (Fig. 3).
The tumor cells form lobules some partly demarcated by thin collagenous septae (hematoxylin and eosin stain, original magnification x 10).
jocmr-09-074-g004.jpg
PMC5127220_01_jocmr-09-074-g004.jpg
F4
The histopathological analysis of our specimen indicated the diagnosis of a meningioma grade I (Figs. 4, 5).
The tumor cells are uniform with oval nuclei with delicate chromatin that on occasion show central clearing or the formation of nuclear inclusions. Psammoma bodies are present (hematoxylin and eosin stain, original magnification x 40).
jocmr-09-074-g005.jpg
PMC5127220_01_jocmr-09-074-g005.jpg
F5
The histopathological analysis of our specimen indicated the diagnosis of a meningioma grade I (Figs. 4, 5).