PMC5702932_01
(a) Chest X-ray: bilateral infiltrations, microcalcifications in chest and abdomen. (b) and (c) Thorax CT: multiple, parenchymal nodules in both lungs, the biggest one 5 mm in diameter. (d) Thorax CT, the slices passing liver: a calcific nodule (At 26 months old).
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fig1
There were bilateral multiple parenchymal nodules, the biggest one being 5 mm, in high-resolution CT (Figure 1).
PMC5702932_02
(a) Chest X-ray: bilateral infiltrations, bronchial thickenings, and air trapping. (b) Thorax CT: bronchiectasis in the left upper lobe and lower lobe, peribronchial thickenings, mucous plaques, and air trapping in both lungs (At four years of age).
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fig2
Despite these measures, she developed bronchiectasis at the age of four (Figure 2).
Identification of de novo autosomal dominant STAT1 mutation in the patient.
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fig3
Parents were wild-type for the gene (Figure 3).