PMC5726690_01
A, B, C: Brown macules on the lateral aspect of the glans
and prepuce of the penis, almost symmetrical on both sides of the
coronal sulcus
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f1
Upon retraction of the foreskin, the lesions appeared as a mirrored image (Figure 1).
Dermoscopy of the macules revealed melanocytic lesions in a compound
pattern. In the periphery, there was fine pigment network and in the
center, dark globules of different sizes. A: lesion on the
glans; B: lesion on the prepuce
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f2
The lesions were separated by a thin streak of non-pigmented skin on the prepuce and it was possible to observe a few globules on the coronal sulcus (Figure 2).
Photomicroscopy of the glans skin. A: Proliferation of
densely pigmented melanocytes along the dermal-epidermal junction and
papillary dermis (Hematoxylin & eosin, X100); B:
Proliferation of densely pigmented melanocytes along the
dermal-epidermal junction and forming nests in the papillary dermis
(Hematoxylin & eosin, X400); C: Melanocytes with
evident nuclei (arrows) (Hematoxylin & eosin, X400)
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f3
Histopathology of both lesions revealed a proliferation of densely pigmented melanocytes with abundant cytoplasm, along the dermal-epidermal junction and forming nests in the papillary dermis suggestive of a compound melanocytic nevus (Figure 3).