PMC6215586_01
Clinical photograph showing diffuse swelling on the left side of the face.
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A 12-year-old boy reported to our institute with a chief complaint of swelling on the left side of the face for the past six months (Figure 1).
OPG showing large unilateral radiolucencies extending from the 1st permanent molar along the ascending ramus up to the neck of the condyle and involving coronoid process and thinning of the lower border and bowing of angle of mandible.
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Photomicrograph showing odontogenic epithelial islands arranged in follicles within the connective tissue stroma (H&E 10x view).
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The histopathological examination showed sheets of odontogenic islands lined by tall columnar cells enclosing stellate reticulum-like cells along with squamous metaplasia in the connective tissue stroma extending into the peripheral epithelium. (Figures 3 and 4).
Photomicrograph showing areas of ameloblast-like cells, stellate reticulum-like cells, individual cell keratinisation, and squamous metaplasia.
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The histopathological examination showed sheets of odontogenic islands lined by tall columnar cells enclosing stellate reticulum-like cells along with squamous metaplasia in the connective tissue stroma extending into the peripheral epithelium. (Figures 3 and 4).
IHC Ki-67 mildly positive in fewer areas.
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IHC Ki-67 also showed mild positivity in fewer areas (Figure 5).
CT scan showing expansile lytic lesion of left ramus of the mandible.
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Further radiological investigations proceeded with CT scan neck (plain and contrast) and CT Brain (Figure 6).
Photomicrograph showing sheets of odontogenic epithelial follicles lined by tall columnar cells enclosing stellate reticulum-like cells within the connective tissue stroma (H&E 4x view).
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fig7
Based on the clinical, radiological, and histopathological examination, a final diagnosis of acanthomatous ameloblastoma was made (Figures 7-9).
Photomicrograph showing follicles lined by tall columnar cells enclosing stellate reticulum-like cells and squamous metaplasia (H&E 40x view).
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fig8
Based on the clinical, radiological, and histopathological examination, a final diagnosis of acanthomatous ameloblastoma was made (Figures 7-9).
Photomicrograph showing reactive lymph nodes (H&E 20x view).
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fig9
Based on the clinical, radiological, and histopathological examination, a final diagnosis of acanthomatous ameloblastoma was made (Figures 7-9).