PMC8114276_01
Liver function tests and relevant medications before, during, and after atorvastatin-induced liver injury. AST, ALT, and ALP were markedly elevated 3 months after initiation of atorvastatin and pioglitazone and normalized after discontinuing both. LFTs remained at baseline after resuming simvastatin and pioglitazone. Potential nonadherence to simvastatin represented by crosshatch pattern. ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate transaminase; LFT, liver function test.
10.1177_23247096211014050-fig1.jpg
PMC8114276_01_10.1177_23247096211014050-fig1.jpg
fig1-23247096211014050
LFTs were notable for an aspartate aminotransferase (AST) of 1093 U/L (upper limit of normal [ULN] 41 U/L), an alanine transaminase (ALT) of 1385 U/L (ULN 58 U/L), and an alkaline phosphatase (ALP) of 265 U/L (ULN 129 U/L; R Factor 11.6; Figure 1). LFTs (see Figure 1). Liver biopsy was therefore not performed.