PMC9106245_01
(a) Orthopantomogram of the mandible showing multiple radiolucent areas, (b) Cone-beam computed tomography of the mandible showing multiple osteolytic lesions with ragged borders
JOMFP-26-104-g001.jpg
PMC9106245_01_JOMFP-26-104-g001.jpg
F1
Cone-beam computed tomography of the mandible revealed large radiolytic lesions on either side, involving the inferior border [Figures 1a and b].
Histopathological image shows sheets of neoplastic cell proliferation with plasmacytic differentiation (H&E, x400)
JOMFP-26-104-g002.jpg
PMC9106245_01_JOMFP-26-104-g002.jpg
F2
Incisional biopsy was performed on the right and left side of the lower jaw and histopathological examination revealed sheets of neoplastic cell proliferation with plasmacytic differentiation [Figure 2].
(a and b) Immunohistochemical staining with CD138 showing diffuse positivity (IHC - CD138, x400)
JOMFP-26-104-g003.jpg
PMC9106245_01_JOMFP-26-104-g003.jpg
F3
CD138, kappa and lambda. CD138 showed diffuse positivity [Figures 3a and b].
Immunohistochemistry showed negative staining with kappa light chain (IHC - kappa light chain, x400)
JOMFP-26-104-g004.jpg
PMC9106245_01_JOMFP-26-104-g004.jpg
F4
The tissue showed negative staining for kappa light chain and lambda light chain staining showed a prevalence of lambda positivity in the neoplastic cells evaluated, confirming the final diagnosis of plasmacytoma [Figures 4 and 5a, b].
(a and b) Immunohistochemical staining with showing diffuse positivity (IHC - lambda light chain, x400)
JOMFP-26-104-g005.jpg
PMC9106245_01_JOMFP-26-104-g005.jpg
F5
The tissue showed negative staining for kappa light chain and lambda light chain staining showed a prevalence of lambda positivity in the neoplastic cells evaluated, confirming the final diagnosis of plasmacytoma [Figures 4 and 5a, b].