PMC3475880_01
Noncontrasted CT brain showing bifrontal lestion with area of focal calcification
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F1
A 51-year-old Chinese female presented with the incidental finding of a large heterogeneously enhancing mass in the frontal lobes after a computer tomography (CT) scan for minor head injury following a fall [Figure 1].
MRI showing bifrontal lesion crossing the midline and displacing the corpus callosum posteriorly (a) axial T2-weighted (b) axial T1-weighted (c) postcontrast axial T1-weighted, and (d) postcontrast sagittal T1-weighted images
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F2
T2-weighted images, and demonstrated avid postgadolinium contrast enhancement [Figure 2]. The lesion showed foci of calcification and peripheral cystic components, with mild perilesional edema and significant mass effect. The corpus callosum was displaced posteriorly.
(a) Low power view showing a cellular tumor with perivascular pseudorosettes and a well demarcated border with the adjacent brain parenchyma (H and E, x 40). (b) An occasional true (ependymal) rosette is identified (H and E, x 400). (c) The tumor is mitotically active and shows areas of necrosis (H and E, x 200). (d) Microvascular proliferation is also present (H and E, x 200)
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F3
Histology showed a well demarcated cellulartumor [Figure 3] with prominent perivascular pseudo-rosettes and very occasional true (ependymal) rosettes.
MRI on postoperative day 1 showing complete tumor resection (a) axial T2-weighted (b) axial T1-weighted (c) postcontrast axial T1-weighted, and (d) postcontrast coronal T1-weighted images
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F4
MRI taken on postoperative day 1 [Figure 4] showed no evidence of residual tumor.