PMC4348588_01
Posteroanterior and lateral chest X-rays of the patient.
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fig1
Routine blood tests and chest X-ray were normal (Figure 1).
Chest CT showed a lesion protruding to the lumen in distal trachea at the posterior wall.
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At chest computed tomography (CT) a mass was seen at the distal trachea, nearly obstructing the lumen (Figure 2).
Bronchoscopic view of the lesion, causing 80% obstruction at the tracheal lumen.
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At fiberoptic bronchoscopic (FOB) evaluation, there was a papillomatous lesion at the posterolateral wall of the distal 1/3 of trachea, causing ~80% obstruction at the lumen (Figure 3).
Bronchoscopic view, tracheal wall after excision of the lesion with cryotherapy.
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In the pathology, squamous epithelial hyperplasia of bronchial epithelium with small papillomatous structures was seen (Figure 4).
Papillary structures made by hyperplastic squamous epithelium are seen in fibrovascular core (H&E, x40), and koilocytic cells with perinuclear vacuolisation are seen in hyperplastic squamous epithelium (H&E, x200).
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There were no dysplastic changes in the epithelial cells (Figure 5).
CT sections at the 6th month: tracheal lumen is normal.
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Computed tomography and bronchoscopic evaluation at the 3rd month of the treatment showed no recurrence (Figure 6) and IFN-alpha treatment was continued for 6 months.