PMC4214049_01
Preoperative intraoral view of the lesion.
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A 63-year-old woman with a history of advanced uterine LMS presented to our center with a painful, ulcerated swelling on the right upper buccal gingiva (Figure 1).
Preoperative axial CT scans with contrast showing left upper alveolar crest lesion.
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A CT scan performed about 1 month after resection revealed an osteolytic lesion of 30 x 35 mm of the upper maxilla (Figure 2); MRI was not performed because the patient was claustrophobic.
(a) Hematoxylin eosin stain of the specimen (2x HPF). (b) Hematoxylin eosin stain of the specimen (10x HPF). (c) Immunohistochemistry showing positivity to a-smooth muscle actin (a-SMA) (2x HPF). (d) Immunohistochemistry showing positivity to a-smooth muscle actin (a-SMA) (10x HPF). ((e) and (f)) Immunohistochemistry revealing a mitotic index (Ki-67) of 90% positivity (2x HPF and 10x HPF).
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Immunohistochemical analysis against monoclonal antibodies for a-smooth muscle actin (a-SMA), desmin, HHF-35, caldesmon, and vimentin was positive; mitotic index (Ki67) was of 90% (Figure 3).