PMC6183653_01
(A) Recalcitrant psoriasis on the lower trunk and gluteal regions of a 72-year-old male before treatment with Cal/BD aerosol foam. (B) Psoriatic lesions after 4 weeks' treatment with Cal/BD aerosol foam.. Abbreviations: BD, betamethasone dipropionate; Cal, calcipotriol.
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Physical examination revealed recalcitrant psoriasis, principally on the lower trunk and gluteal regions (Figure 1A). After 4 weeks' treatment, the psoriatic lesions had markedly improved (Figure 1B) and PASI score had decreased to 1.5.
(A) Recalcitrant psoriasis on the backs of hands in a 78-year-old male before treatment with Cal/BD aerosol foam. (B) Psoriatic lesions after 4 weeks' treatment with Cal/BD aerosol foam.. Abbreviations: BD, betamethasone dipropionate; Cal, calcipotriol.
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Physical examination at presentation revealed recalcitrant psoriasis on the backs of the hands (Figure 2A), buttocks, and thigh. After 4 weeks' treatment, the psoriatic lesions had markedly improved (Figure 2B) and PASI score had decreased to 2.0.
(A) Hyperkeratotic psoriasis on the anterior legs in a 71-year-old male before treatment with Cal/BD aerosol foam. (B) Psoriatic lesions after 4 weeks' treatment with Cal/BD aerosol foam.. Abbreviations: BD, betamethasone dipropionate; Cal, calcipotriol.
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Physical examination at presentation revealed hyper-keratotic psoriatic plaques on the legs and elbows, and the patient was especially troubled by psoriasis on the anterior legs (Figure 3A).
(A) Classic erythematosquamous plaque on the posterior thigh in a 35-year-old male before treatment with Cal/BD aerosol foam. (B) Psoriatic lesion after 4 weeks' treatment with Cal/BD aerosol foam.. Abbreviations: BD, betamethasone dipropionate; Cal, calcipotriol.
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Physical examination at presentation revealed classic psoriatic plaques, each about 3-4 cm in diameter, on the elbows and knees, and on the posterior thigh (Figure 4A). After only 1 week of Cal/BD application, reddening and infiltration of the plaques had significantly decreased (Figure 4B); pruritus had also completely subsided within the first week of treatment.
(A) Moderate-to-severe psoriasis in a 56-year-old male before treatment with Cal/BD aerosol foam. (B) Psoriatic lesion after 4 weeks' treatment with Cal/BD aerosol foam.. Abbreviations: BD, betamethasone dipropionate; Cal, calcipotriol.
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PASI score was 12, DLQI score was 14, and the patient had approximately 13% BSA affected (Figure 5A). Previously, the patient had been treated unsuccessfully with topical corticosteroids, UVB phototherapy, and methotrexate. After 2 weeks' application of Cal/BD foam, a significant clinical response (PASI75) and an improvement of itching were attained (Figure 5B).