PMC3783503_01
Axial gadolinium-enhanced T1-weighted magnetic resonance image shows a mass lesion in the anophthalmic orbit, which is totally occupied by the tumor.
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Gadolinium-enhanced magnetic resonance imaging revealed a contrast enhanced mass measuring 38 mm x 33 mm x 36 mm in the right orbit (Figure 1).
Hematoxylin-eosin stained section shows cells with abundant multi-vacuolated cytoplasm and large nuclei with prominent nucleoli; x400 (A). Adipophilin immunostaining highlights intracellular compartmentalized vacuoles; x400 (B).
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The atypical cells had abundant clear multi-vacuolated cytoplasm, and oval nuclei with discernible nucleoli (Figure 2A). Tumor cells were immunoreactive for adipophilin and perilipin, which are useful markers for sebaceous gland carcinoma (Figure 2B).
Gross appearance of the orbital tumor after exenteration. Note the tumor with well defined margin and enclosed by a fibrous capsule.
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The tumor had well defined margins and was enclosed by a capsule (Figure 3).