PMC6297259_01
Anti-MDA5-associated DM. Eroded violaceous papules and plaques covered by scale and crust over the palmar joint creases and digital tips.
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Eroded violaceous papules and plaques covered by scale and crust were spread over the palmar joint creases and digital tips (Fig 1).
TEN like eruption after prednisone cessation. A, Multiple erosions accompanied by widespread faint erythema on the chest. B, Violaceous plaques over the buttocks and lower limbs.
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Physical examination found a rash composed of multiple erosions, accompanied by faint erythema, involving the face, neck, and chest (Fig 2), which subsequently spread to involve 70% of her body.
Histology of a cutaneous biopsy taken from TEN-like rash in an anti-MDA5-positive dermatomyositis patient. Biopsy section taken from the edge of a bulla shows multiple dyskeratotic cells and areas of epidermal necrosis. (Hematoxylin-eosin stain; original magnification: x20.)
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Histology of skin biopsy disclosed multiple dyskeratotic cells and areas of epidermal necrosis (Fig 3).