PMC7395464_01
(a) Lumbosacral computed tomography showing a central hyperdense image at L1 level suggestive of a intradural lesion occupying almost all the canal with no extension to the foramen and with no bone lesion associated; sagittal plane, (b) pre-operative, coronal plane (c) pre-operative, axial plane.
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F1
The lumbar CT-scan [Figure 1] showed a hyperdense intramedullary tumor arising from the conus medullaris at the L1 vertebrae level.
(a) Lumbosacral computed tomography showing a post- operative laminoplasty and excision of the previous lesion; sagittal plane (b) post-operative, axial plane.
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F2
(a) Hematoxylin and eosin stain x40 - large, irregular cells with moderate pleomorphism, with hyper-chromatic nucleus and prominent nucleoli visible. Some binucleated cells are also identified, (b) Hematoxylin and eosin stain x4 - small magnification of the biopsy fragments, (c) Melan-A 20x - neoplasic cells with cytoplasmic marking.
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F3
Further, primary malignant melanoma was confirmed with histopathology and immunohistochemical (e.g., positive immunoreactivity for S100 protein and Melan A) [Figure 3].