PMC7670749_01
Phylogenetic analysis of the viral protein 1(VP1) gene fragment (240 nt.) of the CVB2 isolate (indicated by black circle) from a fatal case of meningoencephalitis in Brazil in 2018. The tree was generated from a nucleotide sequence alignment using the neighbor-joining algorithm implemented in MEGA 6.0 software using a Kimura two-parameter model and 1000 bootstrap pseudo replicates. Only bootstrap values >70% are shown at the node. The sequence in this study was submitted to GenBank under accession number MN232825. RUS: Russia; AUS: Australia; CHI: China; TAI: Taiwan; ITA: Italy; KEN: Kenya; USA: United States of America; FRA: France; GER: Germany; UK: United Kingdom; FIN: Finland; BRA: Brazil; SEN: Senegal; DEN: Denmark; NIG: Nigeria
1678-9849-rsbmt-54-e20190499-gf1.jpg
PMC7670749_01_1678-9849-rsbmt-54-e20190499-gf1.jpg
f1
Phylogenetic analysis using the VP1 gene fragment sequence confirmed the close relationship (~95%) between the CVB2 identified in this study and European isolates associated with neurological diseases between 2000 and 2007 (Figure 1).