PMC8371243_01
Computed tomographic findings of the anterior mediastinal tumor (A), and pulmonary lesions (B).
gr1.jpg
PMC8371243_01_gr1.jpg
fig1
Computed tomography (CT) revealed an anterior mediastinal mass lesion invading the pericardium (Fig. 1A). CT also confirmed swelling of the mediastinal lymph nodes, bilateral pleural effusion, and pleural dissemination (Fig. 1B).
Microscopic findings of anterior mediastinal tumor (hematoxylin-eosin, original magnification x100).
gr2.jpg
PMC8371243_01_gr2.jpg
fig2
Extracellular mucin pools and signet-ring-like cells were also noted (Fig. 2).
Immunohistochemical staining. Cancer cells are negative for cytokeratin 7 (A) and thyroid transcription factor-1(D), positive for cytokeratin 20 (B), and caudal-type homeobox 2 (C).
gr3.jpg
PMC8371243_01_gr3.jpg
fig3
Immunohistochemically, cancer cells are positive for cytokeratin (CK) 20 and caudal type homeobox 2 (CDX-2), and negative for CK7, estrogen receptor, CD5, and thyroid transcription factor-1 (TTF-1) (Fig. 3).