PMC9860198_01
Clinical course of the present case
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On April 6, 2020, she started sinusitis treatment with 600 mg/day of erythromycin, a potent cytochrome P450 (CYP) 3A4 inhibitor, prescribed by the respiratory department (Figure 1). Her laboratory results, except those of the coagulation test and inflammatory response, did not change throughout the period (Figure 1).
Picture of the necrotic tissue in the left lower leg 20 days after injury
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She presented a 10 cm subcutaneous hematoma and 2- and 4 cm cutaneous ulcers (Figure 2).