PMC8217696_01
Multiple diffuse contrast enhancing lesions with central cavitation. Large lesion in the right occipital lobe and left cerebellum on T1 MRI.
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Follow up magnetic resonance imaging (MRI) after admission showed numerous peripheral enhancing lesions throughout the brain, demonstrating central liquefaction and surrounding edema (Fig. 1).
Diffuse cerebral edema on MRI FLAIR.
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Lesions were surrounded by extensive cerebral edema (Fig. 2).
Right occipital lobe histopathology showing amoebic trophozoites. Basophilic cytoplasm, large nucleus, and prominent nucleolus.
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Pathology report described necrosis with multiple amoebic forms consistent with trophozoites of Balamuthia mandrillaris (Fig. 3).