PMC10175640_01
Hepatocellular liver enzymes and absolute eosinophil count. Trend of hepatocellular liver enzymes and absolute eosinophil counts following treatments with prednisone and mepolizumab in patient 1.
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The trend of hepatocellular liver enzyme levels and absolute eosinophil counts of P1 following treatments with CSs and mepolizumab is presented in  Figure 2 .
Clinical description and skin histopathology of the patients. (A) Clinical presentation of DRESS in patient 2 consisting of diffuse erythematous rash involving the lower limbs. (B) One week following benralizumab therapy, partial resolution of the skin rash. (C) Punch biopsy of skin consisting of hematoxylin and eosin stain demonstrating changes compatible with the clinical diagnosis of DRESS, most notably an inflammatory infiltrate composed of lymphocytes and numerous eosinophils stretching from the epidermis to the deep dermis in x10 magnification. The inset demonstrates eosinophils present in the deep dermis in x100 magnification (arrows). (D) Secondary changes including parakeratosis and interstitial edema with blister formation in the papillary dermis (arrowheads) in x40 magnification.
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The clinical presentation and skin histopathology of P1 and P2 are presented in  Figure 3 .
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