PMC7752786_01
Box-and-whisker plot showing the regional 11C-UCB-J binding for the control group (grey) and scatter plot for DLB patient 1 (amyloid-negative, red) and DLB patient 2 (amyloid-positive, blue). Asterisk symbol indicates the regions with significant decrease for DLB (FDR-corrected p < 0.05). On the right, mean axial 11C-UCB-J scan for controls (grey medallion), DLB patient 1 (red) and DLB patient 2 (blue)
41824_2020_93_Fig1_HTML.jpg
PMC7752786_01_41824_2020_93_Fig1_HTML.jpg
Fig1
Pairwise regional comparisons revealed decreased 11C-UCB-J BPND for both DLB patients compared to controls in extensive cortical regions (10/33 regions) and thalamus, with more prominent changes in parieto-occipital, middle and superior frontal cortices (FDR-corrected p < 0.05) (Fig. 1). Figure 1).