PMC9300819_01
Bone marrow. (A) At low power, bone marrow microscopic examination shows hypercellularity in nodular pattern (arrows) (H&E, 2x). (B) Noncaseating epithelioid granulomas in interstitial (arrow) and paratrabecular loci (*) (H&E, 10x). (C) These granulomas are composed mostly of epithelioid macrophages and a few dispersed lymphocytes (20x, H&E). In detail, macrophages are enlarged by large collections of leprosy bacilli - globi (100x, Faraco-Fite).
fimmu-13-916319-g001.jpg
PMC9300819_01_fimmu-13-916319-g001.jpg
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A bone marrow biopsy (Figures 1, 2 ) revealed the presence of M. leprae forming globi.
Bone Marrow - Epithelioid granuloma composed of macrophages (arrow head) and multinucleated giant cells (*) rich in bacilli, which may present in isolation or bound together forming globi (arrow), what distinguishes M. leprae from other mycobacteria (100x, Faraco-Fite).
fimmu-13-916319-g002.jpg
PMC9300819_01_fimmu-13-916319-g002.jpg
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A bone marrow biopsy (Figures 1, 2 ) revealed the presence of M. leprae forming globi.