PMC5398117_01
(a) Cervical intraepithelial neoplasia III of the uterine cervix with nuclear atypia (x100). (b) In situ tumor sweeps over the endometrium of the lower uterine segment (x40). (c) Strong expression of CD138 in the cervix in situ tumor (x40). (d) strong expression of CD138 in the in situ tumor in the lower uterine segment (x40)
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F1
Microscopically, the ectocervix was lined by squamous epithelium with full thickness dysplasia with nuclear atypia, loss of polarity, and hyperchromasia [Figure 1a]. There was contiguous extension of the dysplastic squamous epithelium into the lower uterine segment replacing the endometrium [Figure 1b].