PMC9663247_01
(a) A 5 cm ovoid, pink-white, minimally scaly, thin plaque on the arm of a 69-year-old female, Fitzpatrick skin type II. (a') Postbiopsy. (b) H&E and (c) Melan-A immunohistochemistry revealing melanoma in situ, lentigo maligna type, on shave biopsy. (d) H&E and (e) Melan-A immunohistochemistry revealing invasive lentigo maligna melanoma, Breslow depth 0.3 mm. All microscopy is performed at 100x total magnification.
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PMC9663247_01_CRIDM2022-2598965.001.jpg
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Examination revealed a 5 cm ovoid pink-white, minimally scaly, thin plaque with intact sensation and without pain or itch (Figure 1(a), a'). Pathology was consistent with a diagnosis of melanoma in situ, lentigo maligna-type (Figures 1(b) and 1(c)). The excision of the clinical residual was significant for invasive lentigo maligna melanoma, Breslow depth 0.3 mm (Figures 1(d) and 1(e)).