PMC5553376_01
Photomicrographs of liver biopsy in hematoxylin and eosin staining showing confluent necrosis involving most of the liver parenchyma (a, magnification x40), modest inflammation and evidence of feathery degeneration and ballooning of hepatocytes in parenchyma (b, x400), and intrahepatic cholestasis (c, x400).
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F1
A liver biopsy showed confluent necrosis involving most of the liver parenchyma, intrahepatic cholestasis, modest inflammation, and evidence of feathery degeneration and ballooning of hepatocytes in parenchyma, but no fat or fibrosis, compatible with toxic ALF (Fig. 1).