PMC9238206_01
Strain elastography and US findings of a clear cell hidradenoma, mimicking an epidermoid tumor in a 46-year-old male.. A. The gray scale ultrasound image shows a well-circumscribed, lobulated, mixed echogenic lesion with small cystic portions and a septum-like structure (arrow) in the subcutaneous fat layer. Some echogenic materials with movement, such as debris movement, are seen. Mild posterior enhancement is also seen.. B. The color Doppler study shows no vascularity in the mass.. C. Strain elastography demonstrates predominantly blue area with a few small green areas in the region of interest, which implies low elasticity (hard lesion).. D. Gross appearance of the specimen shows a multilocular cystic lesion (arrow) with hemorrhagic serous fluid.. E, F. Histopathological features of the lesion demonstrate solid and cystic components. In a large cystic component, a nodule-like tumor (arrow) with multifocal small cystic spaces is observed (H&E stain, x 12.5) (E). The tumor is composed of monotonous poroid cells with round-to-oval nuclei and show partly squamous differentiation and prominent hyalinized stroma (H&E stain, x 200) (F).. H&E = hematoxylin and eosin
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F1
A US showed a 3.2 cm x 1.5 cm-sized, well-circumscribed, lobulated, mixed-echogenic lesion with a small cystic portion in the subcutaneous fat layer (Fig. 1A). It also contained a septum-like structure (arrow on Fig. 1A), and there was no definite vascularity on color Doppler examination (Fig. 1B). Strain elastography (SE) showed predominantly blue with a few small areas of green in the region of interest which implies a low elasticity (hard lesion, Fig. 1C). The gross specimen was a 3.0 cm x 2.8 cm x 2.0 cm-sized, multilocular, cystic lesion with hemorrhagic serous fluid (Fig. 1D). The tumor was composed of monotonous poroid cells with round-to-oval nuclei, and showed partly squamous differentiation and prominent hyalinized stroma (Fig. 1E, F).