PMC6148838_01
The computerized tomographic (a,c,d) showed an intensely contrast-enhancing 23 x 17 x 20 mm mass, arising from the membranous part of the posterior trachea, 1 cm above the carina. This mass showed high FDG uptake on PET-CT (b).
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Chest CT-scan and FDG-PET scan showed an intensely contrast-enhancing endoluminal mass of 2 x 2 cm with a high FDG uptake emerging from the membranous part of the lower trachea, along with sub-occlusion of the two main bronchi (Fig. 1, Fig. 2).
Pre-operative virtual bronchoscopy with the partially obstructive paraganglioma arising from the posterior membranous part of the distal trachea (a). Bronchoscopy at 6 weeks showing a complete healing of the airway without stenosis or muscle flap protrusion (b).
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Control bronchoscopy at 6 weeks showed a complete healing of the airway without stenosis or muscle flap protrusion with macroscopic re-epithelization of the muscle flap (Fig. 2).
Intra-operative view of reconstruction of the carinal defect with the latissimus dorsi muscle flap.
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Inc, Somerville, NJ) (Fig. 3). Intraoperative bronchoscopy showed no dehiscence or endoluminal protrusion of the muscle patch allowing good ventilation.
Photomicrographs of H&E and IHC (magnification: x400) showing tumor cells with abundant eosinophilic cytoplasm arranged in clusters (zellballen pattern) surrounded by S-100-positive sustentacular cells.
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The final pathological examination confirmed the complete resection of paraganglioma with main cells positive for neuroendocrine markers (synaptophysine and chromogranine) and sustentacular cells positive to S-100 protein (Fig. 4).