PMC5224784_01
T2* weighted gradient echo images through the head reveal numerous small hypointense lesions (arrows) throughout the brain due to susceptibility artifact from hemosiderin deposition. These lesions predominantly lie in the corpus callosum and periventricular and subcortical regions.
CCR3-5-39-g001.jpg
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ccr3727-fig-0001
An MRI brain showed multiple widespread microhemorrhages consistent with cerebral fat emboli (Fig. 1), and based on the clinical, hematological, and radiological features, a unifying diagnosis of FES was made.
PMC5224784_02
PMC5224784_03
Necrotic, faintly stained cells (arrowheads) mixed with some normal hemopoietic cells, and cellular debris (circle) on an amorphous background material (arrow).
CCR3-5-39-g002.jpg
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ccr3727-fig-0002
Bone marrow biopsy performed on d4 confirmed extensive bone marrow necrosis (Fig. 2).