PMC3876906_01
Preoperative MRI showing the mass in the right frontal lobe.
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fig1
An MRI 3-Tesla scan of the brain demonstrated a solid, well-demarcated homogeneous mass which may have a dural attachment (Figure 1). The choline monopeak in the tumor corresponds to an extra-axial tumor, and the lack of resonance in the lipid area confirms the diagnosis of an extra-axial tumor and also excludes a metastasis (Figure 1).
A patternless, highly cellular lesion is seen with increased mitotic activity (H&E, x200, original magnification).
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fig2
Sheets of monomorphic cells were interrupted by perivascular pseudorosettes (H&E, x200, original magnification).
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fig3
Paranuclear and ring-like structures were seen in the anti-EMA reaction (anti-EMA, ABC, x200, original magnification).
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fig4
Tumor cell processes were GFAP-positive and built up perivascular pseudorosettes (anti-GFAP, ABC, x200, original magnification).
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fig5
Ki67-index was increased, with up to 30% positive nuclei (anti-Ki67, ABC, x200, original magnification).
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fig6
Postoperative MRI showing that the tumor has been totally removed.
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fig7
Adjuvant local radiotherapy was performed (Figure 7).