PMC6754832_01
Right breast's mass with solid and hyper vascularized components
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MRI showed a 12 x 10 x 6cm mass with solid and hyper vascularized components with significant enhancement (Figure 1). Microbiopsies revealed a malignant proliferation made of dilated, branching vascular structures with a high mitotic index reaching 10 mitoses per 10 high power fields evoking a well-differentiated angiosarcoma (Figure 2).
(A) microphotography showing the vascular nature of the malignant proliferation at low; (B) medium power view
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MRI showed a 12 x 10 x 6cm mass with solid and hyper vascularized components with significant enhancement (Figure 1). Microbiopsies revealed a malignant proliferation made of dilated, branching vascular structures with a high mitotic index reaching 10 mitoses per 10 high power fields evoking a well-differentiated angiosarcoma (Figure 2).
Gross examination revealing the presence of a bluish mass with haemorrhagic changes
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The gross examination showed the presence of a 12.5x11x6 cm bluish mass with haemorrhagic changes (Figure 3).
Microphotography showing the angiosarcomatous proliferation made of endothelial cells
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Microscopic examination confirmed the angiosarcomatous proliferation made of endothelial cells focally producing papillary formations and projecting tufts into the lumen of the vessels (Figure 4).
Microphotography showing intense positivity to anti-CD34 antibodies
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The immunohistochemical study confirmed the angiosarcomatous nature of proliferation since there was a diffuse and intense positivity to anti-CD34 and anti-CD31 antibodies (Figure 5).