PMC4748621_01
Contrast-enhanced computed tomography scan of the sternal lesion: (a) Axial view showing the destructive, exophytic bony lesion (of soft tissue density) over the lower sternum. (b) The coronal view showing the involvement of the costo-chondral junction of the fourth and fifth ribs on the left side. (c) Sagittal view: Showing destructive, exophytic bony lesion (of soft tissue density) over the lower sternum
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F1
Contrast-enhanced computed tomography showed a 4.1 cm x 2.6 cm x 5.5 cm, destructive, exophytic bony lesion (of soft tissue density) over the lower sternum with involvement of the costo-chondral junction of the fourth and fifth ribs on the left side [Figure 1a-c].
Histological examination of the resected sternal lesion: (a) Microcystic spaces which were filled with hyaline or basophilic mucoid material. (b) The stroma withinthe tumor was hyalinized and manifested mucinous or myxoid features. (c) Epithelial and modified myoepithelial cells lining the cysts. Some mitoses can be also seen
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F2
Histopathological studies showed a predominantly cribriform pattern, characterized by the nests of cells with uniformly round and hyperchromatic nuclei [Figure 2a-c], consistent with metastatic ACC.