PMC2816857_01
There is a marked induration of the skin on the posterior neck.
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F1
Physical examination disclosed a symmetric woody induration of the skin on the face, neck, shoulders, trunk, arms, and legs (Fig. 1).
The radiograph of lumbar spine and pelvis shows near total ankylosis of bilateral sacroiliac joints and a bamboo spine appearance with bilateral syndesmophytes (arrows) at the thoracolumbar vertebrae.
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F2
Radiology of the spine and pelvis showed features of advanced AS, including near total ankylosis of bilateral sacroiliac joints and a bamboo spine appearance (Fig. 2).
(A) The collagen bundles are thickened and separated by clear spaces leading to fenestrations of the collagen (hematoxylin and eosin, x200). (B) Mucin deposits are present between the collagen bundles (Alcian blue stain, x200).
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F3
Alcian blue stain demonstrated abundant mucin deposits between collagen bundles (Fig. 3).