PMC5152951_01
Neck and thorax computed tomography
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Neck and thorax computed tomography (CT) revealed a tumor mass of the right supraclavicular region as well as right anterior mediastinum that was connected in the level of superior thoracic aperture; the mass surrounded the great vessels, with compression of the structures (Figure 1).
The H/E staining of the tumor tissue (x25).
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Tumor tissue also showed large necrotic fields and surrounded rare residual small lymphocytes, histiocytes and plasma cells (Figure 2).
Tumor cells were positive for a) CD33 (x50), b) CD34 (x50), c) CD13 (x200), d) CD163 (x200), e) LCA (x200).
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Immunohistochemistry analysis confirmed that tumor cells were positive for CD33, CD34, CD13, CD163 and LCA (Figure 3a-e) but negative for MPO, T-cell and B-cell markers (CD20 and CD79a), NK-cell markers (CD56), plasmacytic markers (CD138), and anaplastic large cell lymphoma markers (CD30 and ALK1).