PMC6743686_01
Brain magnetic resonance imaging preoperative showing a large right thalamic lesion.
SNI-10-41-g001.jpg
PMC6743686_01_SNI-10-41-g001.jpg
F1
April 2016 due to headache, vomiting, and progressive asthenia in the previous 3 weeks. A brain magnetic resonance imaging (MRI) demonstrated a large right thalamic tumor [Figure 1], and the MRI-spectroscopic study showed a high level of choline and low level of N-AcetylAspartate consistent with a high-grade glioma.
Magnetic resonance imaging with gad, 12 months after the operation.
SNI-10-41-g002.jpg
PMC6743686_01_SNI-10-41-g002.jpg
F2
Her clinical conditions improved progressively and in August she began CTX with temozolomide (TMZ) and XRT in a standard way. 12 months after surgery the patient had a moderate left arm paresis with small residual tumor showed on the brain-MRI [Figure 2].
PMC6743686_02
Magnetic resonance imaging with gad on admission, showing a gross frontal glioblastoma multiforme on the right side.
SNI-10-41-g003.jpg
PMC6743686_02_SNI-10-41-g003.jpg
F3
A brain MRI showed a large right frontal tumor [Figure 3].
Magnetic resonance imaging with gad 14 months after the operation.
SNI-10-41-g004.jpg
PMC6743686_02_SNI-10-41-g004.jpg
F4
The patient was evaluated by the oncologists and radiotherapists and began chemotherapy (CTX) and radiotherapy (XRT) (Stupp protocol). 12 months after surgery her clinical conditions progressively deteriorate with signs of regrowth on MRI [Figure 4].