PMC8287358_01
Spontaneous brain CT scan with enhanced contrast, axial slice, showing hypodense
lesions under the right frontal cortices of subacute aspect.
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An emergency computed tomography was performed showing hypo-dense right frontal brain lesions (Figure 1).
Initial MRI. (A, B, C) T2 sequence axial section, flair sequence in coronal section and
diffusion sequence in axial section showing hyper signal lesions under right frontal
cortices. (D) T2 * sequence not showing a hypo signal. (E and F) Sequence T1 not
injected and T1 after injection of gadolinium in axial slices, showing lesions in hypo
signal T1 not injected and without contrast uptake after injection.
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To better characterize, we performed a cerebral magnetic resonance imaging (MRI) which objectified the subcortical lesions in T2 and FLAIR hyper signal, in T1 hypo signal, without restriction of the diffusion sequence and without enhancement after injection of gadolinium (Figure 2).
MRI control: disappearance of the lesions described on the initial MRI in all the
sequences.
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Two weeks after stopping ifosfamide, we performed a control brain MRI which revealed that the previously described brain lesions had disappeared (Figure 3).