PMC7412821_01
Brachydactyly and cone shaped epiphyses seen in patient which is characteristic of ACRDYS
13633_2020_85_Fig1_HTML.jpg
PMC7412821_01_13633_2020_85_Fig1_HTML.jpg
Fig1
Radiographs revealed severe brachymetatarsia, brachymetacarpia, and brachydactyly with cone-shaped epiphyses in the proximal phalanges (Fig. 1).
Linear Growth Chart
13633_2020_85_Fig2_HTML.jpg
PMC7412821_01_13633_2020_85_Fig2_HTML.jpg
Fig2
After 7 months, her annualized growth velocity had increased from 3 cm/year to 11 cm/year and she had grown 6.5 cm (Fig. 2).
At onset of knee pain: Right capital femoral epiphyseal height loss was observed without evidence of slippage. No significant sclerosis
13633_2020_85_Fig3_HTML.jpg
PMC7412821_01_13633_2020_85_Fig3_HTML.jpg
Fig3
Radiographs (Fig. 3) revealed flattening of the right femoral head consistent with LCPD.
PMC7412821_02
Six weeks later: Increased flattening and sclerosis of right capital femoral epiphysis and mild increased fragmentation laterally
13633_2020_85_Fig4_HTML.jpg
PMC7412821_02_13633_2020_85_Fig4_HTML.jpg
Fig4
Six weeks later, radiographs (Fig. 4) revealed further collapse with involvement of the entire femoral head, and she was now using crutches/wheelchair.