PMC6549484_01
H&E stain revealed atrophic fibers of round or angular shapes that arranged in small and large groups with hypertrophied fibers. Fascicular atrophy was seen. Nuclear clumps were noted.
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Moreover, a muscle biopsy of left Biceps brachii was obtained using an open technique (Figures 1 and 2); Histo-pathological examination confirmed a neuropathic pattern with muscle atrophy of mainly type-II fibers, with concomitant denervation and reinnervation processes.
ATPase reaction PH 4.35 revealed fiber type grouping with type-I fibers predominance. Atrophic fibers are mostly type-II.
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Moreover, a muscle biopsy of left Biceps brachii was obtained using an open technique (Figures 1 and 2); Histo-pathological examination confirmed a neuropathic pattern with muscle atrophy of mainly type-II fibers, with concomitant denervation and reinnervation processes.
Recorded EEG in the patient, It was recorded by bipolar setting, with sensitivity of 150 microvolt, high frequency filter of 70 Hz and low frequency filter of 1 Hz.There are generalized epileptiform 2.5-3 Hz irregular sharp and slow wave complexes.
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Both sleep and awake phases were recorded that has been presented in Figure 3.