PMC6642620_01
Biopsy of left breast: (A) Diffuse pattern (100x); (B) Pseudo papilla; (C) Occasional tubular pattern with desmoplastic stroma (400x); (D) Frequent mitosis (400x).
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The impression was made as invasive carcinoma, no special type (NOS) (Figure 1).
Post treatment MRI: (A) Small focus of restricted diffusion in the left breast inner quadrant; (B) Heterogeneous lesions with restricted diffusion in segment VIII of liver suggestive of residual liver metastasis; (C) Lung parenchyma showed normal densities with no evidence of alveolar densities, intrinsic thickening, fibrosis or emphysematous changes - suggestive of no lung metastasis.
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TAC chemotherapy regimen (Figure 3).
Baseline MRI: (A) Malignant mass in the inner quadrant of left breast; (B) Multiple mixed hyperintense necrotic, non-necrotic lesions in liver; (C) Pulmonary nodules with restricted diffusion in lung.
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Overall, in comparison to the baseline MRI (Jun 2018; Figure 2) as per RECIST 1.1 criteria a "partial response" was reported with the NDLS based