PMC6262798_01
(a and b) CT imaging shows prominent ascites and thickening of the mesentery. No apparent tumor can be identified in the peritoneal cavity. (c) MRI shows cT3b prostate cancer directly invading seminal vesicles and the urinary bladder but not the peritoneal cavity. (d) Bone scan revealed metastasis to the sternum, ribs, and pelvis.
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Computed tomography (CT) findings showed prominent ascites and mesenteric thickening (Fig. 1).
(a) HE, (b) PSA, (c) CK7, and (d) CK20. Scale bar = 100mum. Ascites fluid contains adenocarcinoma cells, which are positive for anti-PSA antibody on immunohistochemical staining. CK7 and CK20 were not clearly stained.
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Immunohistochemical staining of the ascitic cell block revealed adenocarcinoma cells positive for anti-PSA antibody (Fig. 2).
After CAB was started, ascites rapidly disappeared and the mesenteric thickening improved with a decrease in the PSA level.
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With a decrease in the PSA level (from 470.153 to 78.108 ng/mL), the ascitic fluid quickly disappeared, and the edema of the lower limb and scrotum also improved (Fig. 3).