PMC8641794_01
SNP array result of different tissues. (A) Karyomapping (chr1) of different tissues in twins. F: father M: mother. Twin1a/b/s: Oral mucosa cells, blood, and sperm in twin1. Twin2 a/b: Oral mucosa cells, blood in twin2. (B) Result of pairwise SNP analysis in genome wide. SNP analysis used the SNPduo Web tool. Identity by state (IBS) 2: both alleles shared between twins; IBS1: single allele shared between twins; IBS0: non-allele shared. Twin1a: Oral mucosa cells twin1. Twin2 a: Oral mucosa cells in twin2.
fgene-12-744890-g001.jpg
PMC8641794_01_fgene-12-744890-g001.jpg
F1
The karyomapping results showed that twin 2 had different genetic karyotypes between her oral mucosal cells and blood cells (Figure 1A), and her blood karyotype was identical to that of twin 1. The karyomapping results also indicated which alleles are shared by the twins (Figure 1B).