PMC5538086_01
Growth of tumor mass around and inside the hemisected kidney; tumor mass, in light brownish color, is encapsulating most of the kidney (C), infiltrating inside the pelvis (B) without reaching the yellowish medulla and cortex (A).
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F1
The tumor is well demarcated and distinguished from the normal renal tissue; it encapsulates the outside of the kidney and infiltrates inside the renal pelvis but it does not expand to the renal parenchyma (Fig. 1).
Hematoxylin and eosin stained kidney tissue section reveals Neoplastic cells arranged in bundles and in streams (100x). The black arrow points at a dense area (Antoni A) and the blue arrow points at a looser area (Antoni B).
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F2
Most of the neoplastic cells were arranged in dense bundles with increased cellularity like Antoni A areas of a classic schwannoma, and some in loosely arranged streams of cells like Antoni B (Fig. 2).
Hematoxylin and eosin stained kidney tissue section shows spindle and oval Neoplastic cells with cartilaginous islets at the middle (400x).
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F3
There were heterologous elements in form of cartilaginous islets (Fig. 3).
Immunohistochemistry (IHC) shows tumor cells are diffusely immunoreactive for S-100 antibody (dark brown). (40x). The dark brown area is an indication for a positive reaction for S-100 antibody (A), where (B) indicates the negative reaction.
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F4