PMC4352626_01
(a and b) T1-weighted imaging after gadolinium administration revealed a tumor with irregular ring-enhancement in the right temporoparietal region (a: axial, b: sagittal). (c) Axial fluid-attenuated inversion recovery imaging revealed the tumor accompanied extensive perifocal edema
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F1
The mass demonstrated irregular ring-enhancement on contrast administration and was accompanied by extensive perifocal edema [Figure 1a-c].
Contrast-enhanced computed tomography revealed multiple hypodense lesions at the head of the pancreas (a), and para-aortic lymph nodes enlargement (b), as indicated the arrows
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F2
Although no obvious lung cancer was identified, abdominal contrast-enhanced CT revealed multiple hypodense lesions at the head of the pancreas with enlargement of the para-aortic lymph nodes [Figure 2a and b].
(a) Microscope analysis revealed the tumor to be a moderately differenciated tubular adenocarcinoma surrounded by an extracellular matrix (H and E, x200). (b) Immunohistochemical stains showed that the tumor cells were positive for cytokeratin-7 (x200)
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F3
Histopathological analysis revealed moderately differentiated tubular adenocarcinoma and immunohistochemical studies showed positive results for cytokeratin 7 (CK7) and negative results for CK20 and thyroid transcription factor 1, consistent with pancreatic adenocarcinoma [Figure 3a and b].