PMC9518660_01
CT image revealed that the intestinal wall of some small intestine in the lower abdomen was significantly thickened and multiple lymph nodes were found in the retroperitoneal space (arrowhead).
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The possibility of lymphoma was considered (Figure 1).
CT image revealed a nodule in the left wall of the bladder (0.8 cm x 0.8 cm).
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CT imaging also revealed a nodule (0.8 cm x 0.8 cm) in the left wall of the bladder (Figure 2).
18F-FDG PET/CT image revealed that the intestinal wall of some small intestine in the lower abdomen was significantly thickened segmentally, multiple lymph nodes were found in the retroperitoneal space, some of them were fused into clusters, and the glucose metabolism was abnormally increased (arrowhead).
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18F-FDG PET/CT image revealed a nodule (1.8 cm x 0.8 cm) in the lingula segment of the left upper lobe (arrowhead).
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Photomicrograph (hematoxylin-eosin stain 200x magnification) revealed a low-grade no-ninvasive urothelial carcinoma of the bladder.
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Microscopic examination revealed a low-grade noninvasive urothelial carcinoma of the bladder (Figure 5).
DLBCL, non-GCB subtype. Photomicrograph (hematoxylin-eosin stain 200x magnification) showed that the lymphoma cells were large, with relatively abundant cytoplasm and irregular cleaved nuclei.
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Laparoscopic lymph node biopsy showed DLBCL (Figures 6 and 7).
Immunohistochemical staining (200x magnification) of lymphoma cells was CD20 (+), PAX-5 (+), CD10 (-), Bcl-6 (+), MUM-1 (+), C-myc (10% +), Bcl-2 (30% +), MUM-1 (+), CD30 (-), CD3 (-), CD5 (-), EBER (-), and Ki-67 (60% +).
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Laparoscopic lymph node biopsy showed DLBCL (Figures 6 and 7).
Pulmonary squamous cell carcinoma. Photomicrograph (hematoxylin-eosin stain 200x magnification) showed that well-moderately differentiated squamous cells.
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The tumor did not invade the surgical resection margins in the bronchial or vascular system or adjacent lymph nodes (Figure 8).
Immunohistochemical staining (100x magnification) of pulmonary carcinoma cells and immunocytochemistry was CK5/6 (+), CK7 (partially +), P40 (+), and TTF-1 (-).
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P40 (+), and TTF-1 (-) (Figure 9), whereas histopathological staging was pT1N0M0. Postoperatively, the patient was discharged after 18 days of rehabilitation.
Follow-up CT scan and PET-CT scan showed no signs of disease relapse. (a) PET-CT scan performed at 1 month after standard chemotherapy, showing complete remission of lymphoma. (b) CT scan performed at 3 months after standard chemotherapy, showing complete remission of lymphoma. (c) CT revealed no signs of relapse in the primary site 3 months after TURBT. (d) CT revealed no signs of relapse in the primary site 3 months after surgical resection of the left upper lobe.
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After 3 months of follow-up, there were no signs of disease relapse (Figure 10).