PMC10315684_01
Fibrinogen activity determined with the Clauss method on the day of dentistry and on the third postoperative day before and after fibrinogen substitution (mg/dl).
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At the morning of tooth extraction, we applied a total of 4g fibrinogen concentrate (Haemocomplettan, CSL Behring) which led to a normalization of immunologically determined fibrinogen levels (0.8 g/l and 2.2 g/l before and after substitution, normal range 1.9-4.3 g/l) and fibrinogen activity determined with the Clauss method (61 mg/dl and 171 mg/dl before and after substitution, normal range 200-400 mg/dl) (Figure 1), thrombin time (25 sec and 14.9 sec before and after substitution, respectively, normal range 10.3-16.6 seconds) and reptilase time (26.4 sec and 18.4 sec before and after substitution, respectively, normal range < 20 sec). Table 1 and fibrinogen activity before and after substitution are also depicted in Figure 1.