PMC8374894_01
Serial chest radiographs. (A) at ICU admission; (B) ECMO day 1; (C) ECMO day 48; (D) Day 44 after extubation before discharge hospital; (E) Following up at mid-January 2021.
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F1
Chest x-ray revealed diffuse opacification in the lung field (Figures 1A,B). Chest CT did not show any significant recovery and compliance remained poor over several weeks following initiation of ECMO (Figure 1C). Significant improvement in his chest CT was observed before discharge (Figure 1D). Significant improvement in his chest CT was observed in mid-January 2021 (Figure 1E).
Timeline of ECMO events.
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F2
In the following days, the membrane oxygenator was changed out four times because of gas exchange failure, apparent thrombus formation on the membrane, and acute D-dimer increases associated with massive clot formation around the hollow-fiber bundles in the oxygenator (Table 1; Figure 2).