PMC6008806_01
Histology of initial vaginal mass. (a) Vaginal nodule showing neoplastic cells with abundant clear cytoplasm and characteristic delicate vascular network (H&E, x20). (b) High power view of the vaginal lesion revealed a clear cell carcinoma (H&E, x200). (c) Neoplastic cells were negative for CK7 (x100). (d) Tumor cells showing complete membranous immunopositivity for CA-IX (x200).
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fig1
A diagnosis of metastatic CCRCC was made (Figure 1).
Histology of recurrent vaginal mass. (a) The clear cell renal cell carcinoma showing areas of inflammation and extensive rhabdoid differentiation (H&E, x100). (b) High power view of the rhabdoid cells observed in the recurrent vaginal excision (H&E, x200).
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fig2
The pathologic examination revealed a CCRCC, with extensive rhabdoid differentiation this time (Figure 2).