PMC6332741_01
Positron emission tomography/computed tomography findings. Positron emission tomography/computed tomography revealed fluorodeoxyglucose accumulation in many pleural lesions (A) and enlarged mediastinal lymph nodes (B)
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Positron emission tomography/computed tomography and enhanced brain magnetic resonance imaging revealed many pleural lesions and enlarged mediastinal lymph nodes (Figure 1).
The bone marrow smear. Peroxidase positive blasts were counted at 38.2% (A) and approximately 20%-30% of the cells were c-kit positive (B)
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In the bone marrow, 38.2% of the nucleated cells were myeloblasts that were positive for peroxidase staining, CD13, CD33, and human leukocyte antigen-D-related in flow cytometry (Figure 2).
Chromosome analysis. The analysis of chromosome abnormalities revealed trisomy 8 and inversion 16 (p13.1q22) in the myeloblasts
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The karyotype analysis revealed 47, XY, +8, inversion 16 (p13.1q22) in 14 of 20 cells (Figure 3).