PMC5556611_01
Case #1 trend in ALT and AST. ALT: alanine aminotransferase; AST: aspartate aminotransferase.
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fig1
AST 9378 U/L) (Figures 1 and 2). Abdominal imaging was negative for acute pathology including vascular liver disease.
Case #1 trend in Total Bilirubin and INR. T. Bili: Total Bilirubin; INR: International Randomized Ratio.
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fig2
AST 9378 U/L) (Figures 1 and 2). Abdominal imaging was negative for acute pathology including vascular liver disease.
PMC5556611_02
Case #2 trend in AST and ALT. ALT: alanine aminotransferase; AST: aspartate aminotransferase.
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fig3
On presentation, she was febrile and tachycardic with laboratory data significant for aminotransferase elevation (ALT 998 U/L, AST 4559 U/L) and disseminated intravascular coagulopathy (DIC) (Figures 3 and 4).
Case #2 trend in Total Bilirubin and INR. T. Bili: Total Bilirubin; INR: International Randomized Ratio.
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fig4
On presentation, she was febrile and tachycardic with laboratory data significant for aminotransferase elevation (ALT 998 U/L, AST 4559 U/L) and disseminated intravascular coagulopathy (DIC) (Figures 3 and 4).
PMC5556611_03
Case #3 trend in AST and ALT. ALT: alanine aminotransferase; AST: aspartate aminotransferase.
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fig5
On postoperative day (POD) 8, she had an acute increase in aminotransferases (ALT of 712 U/L, AST of 780 U/L) with all other values within normal limits (Figures 5 and 6); liver ultrasound did not show abnormalities.
Case #3 trend in Total Bilirubin and INR. T. Bili: Total Bilirubin; INR: International Randomized Ratio.
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fig6
On postoperative day (POD) 8, she had an acute increase in aminotransferases (ALT of 712 U/L, AST of 780 U/L) with all other values within normal limits (Figures 5 and 6); liver ultrasound did not show abnormalities.
Liver biopsy from patient 3 showing intranuclear viral inclusions within the necrotic areas.
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fig7
She underwent laparotomy for removal of the aneurysm and liver biopsy on POD 8 that showed patchy areas of hepatocyte necrosis (Figures 7 and 8).
HSV immunostain from liver biopsy (patient 3).
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fig8
She underwent laparotomy for removal of the aneurysm and liver biopsy on POD 8 that showed patchy areas of hepatocyte necrosis (Figures 7 and 8).