PMC6015694_01
Histopathology. (a-c) A polypoidal lesion lined by hyperplastic stratified squamous epithelium. Subepithelium shows a paucicellular mesenchymal tumour comprising small, bland, spindle, or stellate-shaped cells with small and hyperchromatic nuclei and inconspicuous cytoplasm dispersed in an abundant myxoid stroma. Cellular pleomorphism, mitotic figures, and necrosis are absent. (e-f) Results of immunohistochemistry with CD34, SMA, and S-100. The tumour cells are immunonegative for CD34, smooth muscle actin (SMA), and S100 ((a) HE 40x, (b) HE 100x, (c) HE 200x, (d) CD34 200x, (e) SMA 200x, and (f) S100 200x).
CRIOT2018-6868737.001.jpg
PMC6015694_01_CRIOT2018-6868737.001.jpg
fig1
On histological examination, our case showed a polypoidal tumour lined by hyperplastic stratified squamous epithelium (Figure 1(a)). The latter was paucicellular formed by small, bland, spindle to stellate cells having indistinct cytoplasmic margins and hyperchromatic nuclei (Figure 1(b)). No significant atypia or mitotic activity or any necrosis was noted (Figure 1(c)). Immunohistochemically (IHC), the cells were negative for CD34, smooth muscle actin (SMA), and S100 (Figures 1(d)-1(f)).