PMC6419389_01
Abdominal magnetic resonance imaging findings. A contrast-enhanced T1W MRI showed a single, round, hypodense lesion with peripheral contrast enhancement in the left lobe of the liver.
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Magnetic resonance imaging revealed a lesion with inhomogeneous enhancement in the left lateral lobe of the liver, measuring 3.9 cm x 3.8 cm (Figure 1).
Pathological investigation identified hepatic epithelioid hemangioendothelioma: (A) Tumor cells manifested as epithelioid with rich cytoplasm, some of which revealed intracytoplasmic vascular lumen formation containing erythrocytes (HEx400). (B) immunohistochemistry showed that the tumor was positive for CD34 (HEx100); (C) immunohistochemistry showed that the tumor was positive for CD31 (HEx400); (D) immunohistochemistry showed that the tumor was positive for factorVIII-related antigen (HEx400).
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Epithelioid tumor cells were filled with vacuoles, some of which contained erythrocytes (Figure 2A). Immunohistochemically, the tumor cells were positive for endothelial marker CD34 (Figure 2B), CD31 (Figure 2C) and factorVI-II-related antigen (Figure 2D), confirming the vascular nature of the tumor and contributing to the final diagnosis of HEHE.