PMC2821305_01
Immunohistochemically, the carcinoma cells, were focally positive for Cytokeratin (CK) 20 (a), but negative for CK 7 (b). This CK staining pattern suggested that the skin tumor was a metastasis from the previously resected rectal cancer.
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PMC2821305_01_1757-1626-3-28-1.jpg
F1
A small 0.5 cm diameter ulcer on the upper lip developed after 42 months following the removal of the primary tumor, and biopsy confirmed metastasis of the colorectal adenocarcinoma (Figure 1a. and 1b).