PMC9338354_01
Computed tomography defining the extent of the lesion.
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F1
A computer tomography revealed a well-defined horizontally oval homogenously enhancing lesion measuring 23 x 17 x 30 mm in Craniocaudal x Anteroposterior x Transverse dimensions noted in the right gingiva-buccal sulcus with broad base toward mandible extending from central incisors to second premolar [Figure 1].
Resection of the lesion in toto.
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F2
The lesion was carefully separated from the underlying the tissues, free margins identified, dissected, and removed in toto [Figure 2].
Histopathological examination of the excised specimen under x40.
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F3
Histopathological examination (HE) showed nodular tissue devoid of lining epithelium, composed of a tumor arranged in sheets and perivascular pattern [Figure 3].
Immunohistochemistry slides revealed the cells positive for CD99.
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F4
IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
Immunohistochemistry slides revealed the cells positive for spinal muscular atrophy.
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F5
IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
Immunohistochemistry slides revealed the cells positive for ERG.
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F6
IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
Immunohistochemistry slides revealed the cells positive for Ki67.
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F7
Ki67 index was 20%, giving final diagnosis as malignant small round cell tumor favoring ES [Figure 7].