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The trend of warfarin dose and INR.
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Day 9 (Figure 1 shows the changes in warfarin dose and INR). During the following 12 days, the INR did not achieve the therapeutic goal and remained at 0.97-1.00 despite the warfarin dosage being increased 4.5-fold (27 mg vs 6 mg). Due to the failure to reach target range, we prescribed enoxaparin 6,000 IU BID instead, and switched back to dabigatran 150 mg BID when discharged.