PMC10020610_01
Electroencephalogram (EEG) and changes in brain magnetic resonance imaging (MRI) of patient 1. The left temporo-occipital polymorphic delta and theta activities were observed in the EEG of the patient in the waking phase at disease onset (A, red rectangle). MRI T2/fluid-attenuated inversion recovery (FLAIR) hyperintensities in the hippocampal gyrus in the left medial temporal lobe (B and C). Improvement of abnormal signal in MRI T2/FLAIR (D and E) three years after treatment.
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F1
Persistent polymorphic delta and theta rhythms were observed in the left temporo-occipital region during wakefulness and sleep (Figure 1A). On day 23 after disease onset, brain MRI exhibited hyperintensities on T2 weighted image (T2WI) and fluid-attenuated inversion recovery (FLAIR) in the left medial temporal hippocampus (Figures 1B,C). Re-examination of brain MRI indicated a slight improvement in abnormal hippocampal signals, which were significantly improved three years after disease onset (Figures 1D,E).