PMC8545553_01
Abdominal CT scan taken at the L5 level, demonstrating focal mucosal thickening and dilation of the ascending and proximal descending colon.
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Abdominal CT revealed focal mucosal thickening in the middescending colon, as well as dilation and mild mucosal thickening in proximal segments of the colon (Figure 1).
H&E demonstrating fissuring ulcer (tumor not in view) at 40 magnification (4x).
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Histopathological examination of the surgical specimen revealed a fissuring ulcer typical for Crohn's disease (Figure 2) but also demonstrated a proliferation of cells with spindle to stellate shaped nuclei, intermixed mast cells, and no appreciable mitotic figures.
H&E demonstrating SFT with focal invasion of the submucosa at 20 magnification (2x).
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This cell proliferation extended from the subserosa into the muscularis propria and focally into the submucosa at the area of fissuring, ultimately protruding into the bowel (Figures 3 and 4).
H&E from stricture site with tumor in view (bottom right) at 40 magnification (4x).
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This cell proliferation extended from the subserosa into the muscularis propria and focally into the submucosa at the area of fissuring, ultimately protruding into the bowel (Figures 3 and 4).
Nuclear STAT-6 positivity at 600 magnification (60x).
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The spindle/stellate cells were STAT-6 nuclear positive (Figure 5) and cytoplasmic CD34 positive (Figure 6).
CD34 stain marking the cytoplasm of the stellate and spindle cells as well as a staghorn vessel at 200 magnification (20x).
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The spindle/stellate cells were STAT-6 nuclear positive (Figure 5) and cytoplasmic CD34 positive (Figure 6). Blood vessels are also marked with CD34 (Figure 6).