PMC5362844_01
Erosive-ulcerative lesions on the ventral abdomen, perivulvar region and medial aspect of the front and hindlimbs of a 5-year-old, spayed female domestic shorthair cat
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On dermatological examination, there were large areas of erosion/ulceration due to epidermal detachment affecting the ventral neck, abdomen, vulvar lips and perivulvar region, periungual skin and medial aspect of the front and hindlimbs (Figures 1 and 2); the footpads were unaffected.
Close-up of an erosive-ulcerative lesion due to epidermal detachment on the ventral abdomen
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On dermatological examination, there were large areas of erosion/ulceration due to epidermal detachment affecting the ventral neck, abdomen, vulvar lips and perivulvar region, periungual skin and medial aspect of the front and hindlimbs (Figures 1 and 2); the footpads were unaffected.
Erosive-ulcerative and crusted lesions on the medial and lateral canthus of both eyes
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Erosive-ulcerative and crusted lesions were apparent on the medial and lateral canthus of both eyes (Figure 3).
Light photomicrograph of a section of affected skin, showing suprabasal epidermal detachment and follicular atrophy. No sebaceous glands are detected (haematoxylin and eosin, bar = 200 microm)
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There was a subepidermal mononuclear infiltrate, hair follicle telogenisation and atrophy, and a lymphocytic infiltrate was apparent in the follicular infundibulum (Figures 4-7).
Light photomicrograph of a section of affected skin, showing apoptotic cells at various levels of the epidermis, vacuolar degeneration of basal cells and subepidermal mononuclear infiltrate (haematoxylin and eosin, bar = 50 microm)
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There was a subepidermal mononuclear infiltrate, hair follicle telogenisation and atrophy, and a lymphocytic infiltrate was apparent in the follicular infundibulum (Figures 4-7).
Epidermal necrosis due to confluence of multiple apoptotic cells (haematoxylin and eosin, bar = 50 microm)
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There was a subepidermal mononuclear infiltrate, hair follicle telogenisation and atrophy, and a lymphocytic infiltrate was apparent in the follicular infundibulum (Figures 4-7).
Lymphocytic infiltrate in the follicular infundibulum (haematoxylin and eosin, bar = 50 microm)
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There was a subepidermal mononuclear infiltrate, hair follicle telogenisation and atrophy, and a lymphocytic infiltrate was apparent in the follicular infundibulum (Figures 4-7).