PMC5438013_01
CT abdomen - pelvis.
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Figure1
This demonstrated a large heterogeneous right renal mass with suggestion of active bleeding consistent with a hemorrhagic renal cell cancer (Figure 1).
Gross pathology demonstrates near diffuse replacement of bisected renal parenchyma by infiltrative tumor, extending into perinephric adipose tissue. The proximal ureteral wall (left) is markedly thickened and involved by lymphoma.
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Figure2
The pathologic specimen grossly showed a firm, diffusely infiltrative mass occupying the majority of the renal parenchyma with gross extension into perinephric adipose tissue (Figure 2).
H & E slide 200x. Diffusely infiltrative diffuse large B-cell lymphoma.
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Figure3
Microscopy of the mass revealed a population of large cells with atypical nucleoli, abundant mitoses, and prominent clear to eosinophilic cytoplasm (Figure 3).
CD20 IHC 200x. Diffuse membranous staining for CD20, consistent with B-cell origin.
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Figure4
This confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL) (Figure 4).