PMC6883303_01
Axial (A and B) and coronal (C and D) MRI (MPRAGE) demonstrating placement of bilateral depth electrodes. The deepest contacts of the anterior electrodes are located in the amygdala (C) and posterior electrodes located in the hippocampus (D).
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Bitemporal depth electrodes were implanted with the deepest contacts targeted at the amygdala and hippocampus (Fig. 1).
EEG depth electrode recordings. (A) Seizure onset is observed in the right amygdala (electrode contacts RAMYG1 and RAMYG2) and right hippocampus (electrode contacts RHIPP1 and RHIPP2). (B) Seizure onset is observed in the left amygdala (electrode contacts LAMYG1 and LAMYG2) and left hippocampus (LHIPP1 and LHIPP2).
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Ictal onset was documented independently from the deepest electrode contacts (amygdala and hippocampus) of both the right and left temporal electrodes (Fig. 2). Twelve focal seizures with alteration in consciousness were recorded with focal ictal onset in the right amygdala and hippocampus and six were recorded originating from the left amygdala and hippocampus (Fig. 2).