PMC7201833_01
CT scan of the neck and soft tissue showing and infiltrative mass on the right skull base extending to the right jugular and stylomastoid foramen (a) encasing and occluding the right jugular vein (b). MRI confirms a soft-tissue mass on the skull base without intracranial involvement (c and d).
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CT and magnetic resonance imaging (MRI) of the neck and soft tissue showed an infiltrative soft-tissue right skull base mass extending into the inferior margin of the right jugular foramen, right stylomastoid foramen, deep and superficial lobes of the right parotid gland, the right temporomandibular junction, and styloglossus muscle also causing displacement of the internal carotid artery, encasing the internal jugular vein to the point of occlusion.  Figure 1.
CT scan of the chest and abdomen showing multiple soft-tissue masses involving the anterior mediastinum (a), left axillary, (b) and abdominal subcutaneous tissue (c and d).
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CT scan of the chest, abdomen, and pelvis showed multiple soft-tissue masses in the anterior mediastinum (4 x 1.5 cm), left renal hilum (1.7 x 1.9 cm), left paraspinal area (3.6 x 4 cm), and subcutaneous tissue in the abdomen and pelvis Figure 2.
Bone marrow biopsy showed a hypercellular bone marrow with a diffuse infiltrate of large myeloid blast cells staining positive for CD34 and MPO markers in immunohistochemistry studies.
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Figures 3 and 4.
Core-needle biopsy shows a large atypical monomorphous infiltrate staining strongly for CD34 and MPO diffusely.
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Figures 3 and 4.