PMC8423354_01
Maculopapular skin rash on legs and feet.
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PMC8423354_01_fphar-12-707967-g001.jpg
F1
Large erythema was observed in many parts of the body, along with some prominent skin areas and pigmentation (Figure 1) and she was given the antihistamine diphenhydramine.
Epidermal exfoliation of upper limbs (BSA less than 10%).
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PMC8423354_01_fphar-12-707967-g002.jpg
F2
Furthermore, she developed mild swelling of oropharyngeal mucosa with repeated bleeding and scabbing, resulting in mouth opening and swallowing difficulties (Figure 2), but refused to undergo skin biopsy.
A large exfoliated area of the body (BSA more than 30%).
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PMC8423354_01_fphar-12-707967-g003.jpg
F3
Clear blisters locally appeared, presenting apparent perineal skin damage, with skin loss over 30% of BSA ( Figure 3 ).