PMC9968420_01
Aplasia cutis congenita in case 1 at birth (before treatment). Symmetric skin defects apparent in both legs. Subcutaneous fat and vessels are apparent.
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The underlying adipose tissue, vessels, and muscles were visible, as shown in Figure 1. 
Aplasia cutis congenita in case 1. (A): At 1 mo; (B): At 6 mo. The skin defect healed.
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Normal skin began to grow over the lesions on day 30, as shown in Figure 2A. When the patient was approximately 6-months-old, the skin defects healed without any complications, as shown in Figure 2B.
PMC9968420_02
Aplasia cutis congenita in case 2. Skin ulcers with crusting and effusion in both legs. Several superficial crusts had been removed.
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The sizes of the skin lesions were about 10cm2 on the right leg and 4cm2 on the left leg, which are shown in Figure 3. 