PMC9771717_01
(A) 68Ga-PSMA PET coronal, axial and sagittal views demonstrating no abnormal heterogenous and (B) 16F-FDG-PET coronal, axial and sagittal views demonstrating abnormal heterogenous uptake throughout the penis, without other avid areas.
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It identified diffuse abnormal moderate-high intensity heterogeneous 18F-FDG uptake throughout almost the whole penile shaft (Fig. 1).
(A) Macroscopic dissection of penile specimen showing tumour invasion within the corpus cavernosum, indicated by the moth-eaten appearance due to the massive infiltration by carcinoma and (B) H&E, x20 magnification. The corpus cavernosum is heavily infiltrated by malignant cells arranged in glands, situated within the stroma and in vascular spaces (arrows).
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Macroscopically, tumour invasion into the corpus cavernosum was seen throughout the entire length (Fig. 2a and b).