PMC8093448_01
MRI obtained from brain. Images of brain MRI proposed mostly symmetric, cortical, and juxta-cortical high T1 and T2 signal abnormality, in bilateral parieto-occipital lobes.
fped-09-565778-g0001.jpg
PMC8093448_01_fped-09-565778-g0001.jpg
F1
A few differential diagnoses were proposed; however, it was mostly compatible with viral encephalitis, with possible parenchymal hemorrhagic components (Figure 1).
Real-time RT-PCR graph. Real-time RT-PCR showed the presence of SARS-CoV-2 genome in both the CSF (A) and respiratory (B) samples, targeting the SARS-CoV-2 E gene. The positive CSF result was confirmed by another real-time RT-PCR test targeting the SARS-CoV-2N and ORF1ab genes (C).
fped-09-565778-g0002.jpg
PMC8093448_01_fped-09-565778-g0002.jpg
F2
The test showed that SARS-CoV-2 RNA was present in both the nasopharyngeal swab and CSF samples with the same cycle threshold (Figure 2).
CT obtained from chest. Chest CT showed underlying bronchopneumonic lung involvement.
fped-09-565778-g0003.jpg
PMC8093448_01_fped-09-565778-g0003.jpg
F3
After confirmation of COVID-19 by real-time RT-PCR, bilateral peripheral consolidations in RUL and superior segment of LLL in a spinal chest CT scan showed underlying bronchopneumonic lung involvement (Figure 3).