PMC7184796_01
Hemorrhagic crust, scaly erosion on the lips, and generalized erythroderma with some foci of atypical target lesions on the face, trunk, and upper extremities (a, b).
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F1
Bilateral conjunctival injection, scaly hemorrhagic crusted erosion on both upper and lower lips, as well as mild erosion on bilateral buccal mucosa and genital site were noted (Fig. 1).
Superficial perivascular infiltration (predominately consisting of lymphocytes and eosinophils), mild epidermal hyperplasia, basal vacuolization, exocytosis, scattered necrotic keratinocytes, and prominent melanophages. Hematoxylin-eosin, original magnification x400.
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F2
Routine histopathology demonstrated superficial perivascular infiltration (predominately consisting of lymphocytes and eosinophils), mild epidermal hyperplasia, basal vacuolization, exocytosis, scattered necrotic keratinocyte, as well as prominent melanophages (Fig. 2).
Direct immunofluorescent study showed intercellular deposition of IgG resembling chicken wire feature and linear basement membrane zone staining with IgG (a) and C3 (b).
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F3
Direct immunofluorescence study showed intercellular deposition of IgG resembling chicken wire feature and linear basement membrane zone staining with IgG and C3 (Fig. 3).