PMC8720232_01
uroscanner - left kidney, site of a vascularized tissue mass of 8 cm long, spontaneously hypodense and strongly enhanced after a contrast product injection, with central necrosis and washing out late (arrows)
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F1
The right kidney and other organs were normal (Figure 1).
tumor left kidney (source: pathological cytology laboratory collection from "La Paix" University Hospital); A) fresh piece of left nephrectomy, showing an intact capsule (white arrow); B) section and opening of the left nephrectomy piece by its lateral edge showing a large tumor formation, yellowish white, associated with necrotic and hemorrhagic changes, occupying almost the entire kidney (black arrow)
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F2
It presented foci of central necrotic changes (Figure 2).
poorly differentiated squamous cell carcinoma with anaplastic focus of the left kidney; HE x100 (source: pathological cytology laboratory collection of the DANTEC CHU); often cohesive layers and clumps of atypical, poorly differentiated, dyskaryotic, hyperchromatic squamous epithelial cells, infiltrating a fibro-inflammatory stroma (arrows)
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F3
The histology showed an infiltrating poorly differentiated squamous cell carcinoma (Figure 3), originating from the metaplastic epithelial lining of the calyxes (Figure 4).
carcinoma in-situ vs high-grade dysplasia of the epithelial lining of the calyx; HE x 100 (source: pathological cytology laboratory collection from CHU le DANTEC) Malpighian metaplasia of the calyx urothelium, presenting with high-grade dysplasia versus carcinoma in-situ (arrows)
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F4
The histology showed an infiltrating poorly differentiated squamous cell carcinoma (Figure 3), originating from the metaplastic epithelial lining of the calyxes (Figure 4). We noted the presence of epidermoidal metaplasia with high-grade dysplasia versus squamous cell carcinoma in situ at the level of the epithelial lining of the pelvis (Figure 4).