PMC5872674_01
Necrotic tumor in the upper pole of the spleen.
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fig1
The necrotic tumor was 3 cm (Figure 1).
Hematoxylin and eosin staining, x200. Microscopically, the tumor comprised epithelial cells (Arrow), with an eosinophilic cytoplasm and an abnormal core.
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fig2
Microscopically, the tumor comprised epithelial cells, with an eosinophilic cytoplasm and an abnormal core (Figure 2).
Immunostaining of the tumor was performed with TTF-1, CK7, and CK20, all of which were positive (x200).
CRIS2018-2620301.003.jpg
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fig3
CK7, and CK20, all of which were positive (Figure 3). CK7 is a marker used to assess the reactivity of tumor membrane cells, while TTF-1 is a nuclear stain of tumor cells.