PMC4782651_01
Clean-based, well-delimited ulcer on the lateral border of the tongue
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After admission, clean-based ulcers were noticed, one on the lateral border of the tongue and another on the dorsum of the penis (Figures 1 and 2).
Clean-based, well-delimited ulcer on the dorsum of the penis
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After admission, clean-based ulcers were noticed, one on the lateral border of the tongue and another on the dorsum of the penis (Figures 1 and 2).
Partial surface ulceration and vessels with endothelial cells with large
nuclei and ample cytoplasm, assuming an epithelioid aspect. In the lower
part of the photomicrograph, a vessel occluded by a thrombus can be
seen. HE, 100X
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The histopathological examination revealed ulceration, occlusion of some vessels by thrombi and prominent endothelial cells with conspicuous cytoplasm and markedly enlarged nuclei containing CMV inclusion corpuscles, resulting in diagnosis of cytomegalovirus infection (Figures 3, 4 and 5.
Endothelial cells with markedly augmented nuclei, rough nucleoli and
ample cytoplasm. HE, 400X
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The histopathological examination revealed ulceration, occlusion of some vessels by thrombi and prominent endothelial cells with conspicuous cytoplasm and markedly enlarged nuclei containing CMV inclusion corpuscles, resulting in diagnosis of cytomegalovirus infection (Figures 3, 4 and 5.
Eosinophilic corpuscle of viral inclusion, surrounded by a light halo in
the cytoplasm of an endothelial cell with an epithelioid aspect. HE,
400X
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The histopathological examination revealed ulceration, occlusion of some vessels by thrombi and prominent endothelial cells with conspicuous cytoplasm and markedly enlarged nuclei containing CMV inclusion corpuscles, resulting in diagnosis of cytomegalovirus infection (Figures 3, 4 and 5.
Agarose gel image after electrophoresis, with positive PCR results for
DNA of CMV in the penile ulcer. M: Marker of molecular weight. C -:
Negative control. C +: Positive control. A: Sample of the penile ulcer
with a band at the level compared to positive control, which confirms
the presence of DNA of the CMV in this sample
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The qualitative PCR for DNA of the CMV was positive in skin samples, as well as the antigenemia assay on peripheral blood (Figure 6).