PMC5619109_01
[A,B] Axial T1-weighted magnetic resonance imaging shows
symmetrical bilateral hyperintensities involving the substantia nigra
(arrow in A), the anterior midbrain (curved arrow in A) and the globus
pallidus (arrow in B). The putamen, caudate, thalamus (lines in B) and
red nucleus (line in A) are spared. [C,D] Sagittal
T1-weighted magnetic resonance imaging also demonstrates
hyperintensities in the globus pallidus (arrow in C) and substantia
nigra (arrow in D).
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f1
The putamen, caudate nucleus, thalamus, the red nucleus, and the cerebellum were spared (Figure 1). T2-weighted images disclosed small foci of hyperintensities in subcortical and deep white matter (not shown).
MR-spectroscopy. The main resonance peaks correspond to N-acetylaspartate
(NAA, 2.0 ppm), glutamine glutamate (Glx, 2.1-2.5 ppm), creatine
phosphocreatine (Cr, 3.02 ppm), choline-containing compounds (Cho, 3.2
ppm), and myo-inositol (Ins, 3.55 ppm). The initial spectrum showed no
increase in the glutamate glutamine region and a decrease in the
myo-inositol and choline resonances.
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MR -spectroscopy showed no anomalous peaks (Figure 2).