PMC5303848_01
(a) Histology of the dense collagenous sclerosing lesion with acute and chronic inflammatory cells (10x objective). (b) Histology demonstrating significant numbers of eosinophils in the inflammatory infiltrate which surrounds a vessel (circled) (40x objective). (c) Positive staining of the lesion's cells for vimentin with immunohistochemistry (40x objective). (d) Negative staining for S100 and AE1/AE3 (40x objective).
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fig1
Histology of the lesion under low power view (20x objective) revealed dense collagenous sclerosing lesion with acute and chronic inflammatory cells and examination under high power (40x objective) revealed significant numbers of eosinophil in the inflammatory infiltrate which surrounds vessels (see Figure 1). Lesion also showed positive staining for vimentin and negative for S100 and AE1/AE3 (see Figure 1).
Axial section of CT scan showing left-sided laryngeal asymmetry and homogenous soft tissue mass in the subglottic region.
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fig2
Imaging with CT scan that was carried out two weeks after biopsy confirmed laryngeal asymmetry; the lesion appeared homogenous with no surrounding cartilaginous or bony invasion (see Figure 2).
T1-weighted MRI scan showing homogenous soft tissue mass in the left subglottic region.
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fig3
MRI confirmed soft tissue mass approximately 1 cm in diameter confined to the subglottic region (see Figure 3).
View of the glottis and superior aspect of the subglottic mass.
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fig4
This time precautions were taken not to traumatise the lesion and vocal cords during intubation with microlaryngeal tube (see Figure 4).