PMC6214881_01
Chest computed tomography; case report 1. A. Multiple irregular-shaped soft-tissue lesions in both lungs. A soft-tissue infiltration is seen in S10 of the right lower lobe. B. Six months later: the soft-tissue infiltration previously seen in S10 of the right lung has transformed into a thick-walled cavity.
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The CT scan (Fig. 1A) revealed multiple irregular-shaped soft-tissue nodules in both lungs with normal lung tissue around them. In 6 months, the CT scan showed that the soft-tissue infiltration previously seen in the right lung transformed into a thick-walled cavity (Fig. 1B).
A. Case report 1. Tracheal respiratory papillomatosis showing squamous cover epithelium, many vessels in the stroma (hematoxylin and eosin stain x 50). B. Case report 2. Proliferating squamous epithelium, in some places with atypia; the hybridisation staining for HPV subtype 16 (hematoxylin and eosin stain x 180).
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Aggressive types of HPV (HPV 16, HPV 6, HPV 11) were present in brush biopsy specimens (Fig. 2B).
PMC6214881_02
A. Case report 1. Tracheal respiratory papillomatosis showing squamous cover epithelium, many vessels in the stroma (hematoxylin and eosin stain x 50). B. Case report 2. Proliferating squamous epithelium, in some places with atypia; the hybridisation staining for HPV subtype 16 (hematoxylin and eosin stain x 180).
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Aggressive types of HPV (HPV 16, HPV 6, HPV 11) were present in brush biopsy specimens (Fig. 2B).
Chest computed tomography; case report 2. Multiple cavitary lesions in both lungs.
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Ten months later, though the patient remained clinically stable, CT images showed a significant worsening: the number of cavitary and nodular lesions increased in both lungs (Fig. 3).
PMC6214881_03
Case report 3. A. Chest computed tomography, communication between the pulmonary cavity and the right lateral basal bronchus (B9). B. Lung cancer development in right upper lobe.
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A bronchial lumen bordered on cavitary lesions in the right lateral basal segment (S9) (suspected communication) (Fig. 4A). Squamous cell carcinoma of the right upper lobe was diagnosed in September 2018 (Fig. 4B).