PMC7336218_01
CT scans showing the tumor (a) and the metastatic liver lesion (b) at diagnosis.
CRIONM2020-6817407.001.jpg
PMC7336218_01_CRIONM2020-6817407.001.jpg
fig1
A computed tomography (CT) scan of the chest, abdomen, and pelvis showed a 74*76*155 mm noncalcified presacral soft tissue mass with a 50*43*47 mm metastatic nodule within the liver (Figure 1).
Low magnification: tumor proliferation arraigned in papillary, tubular configuration.
CRIONM2020-6817407.002.jpg
PMC7336218_01_CRIONM2020-6817407.002.jpg
fig2
A liver biopsy was then performed that histologically consisted of primitive pseudostratified neuroepithelial cells, arranged in papillary and tubular configurations (Figures 2 and 3).
At higher magnification: the cells have a low cytoplasm and hyperchromatic nuclei, conferring a basophilic appearance to the tumor.
CRIONM2020-6817407.003.jpg
PMC7336218_01_CRIONM2020-6817407.003.jpg
fig3
A liver biopsy was then performed that histologically consisted of primitive pseudostratified neuroepithelial cells, arranged in papillary and tubular configurations (Figures 2 and 3).
Positivity of neoplastic cells (a) for the cytokeratin AE1AE3 (clone AE1AE3), (b) for CD56 (clone 123C3), and (c) for CD99 (clone 12E7).
CRIONM2020-6817407.004.jpg
PMC7336218_01_CRIONM2020-6817407.004.jpg
fig4
Immunohistochemically, the tumor cells were positive for PS100, CKAE1AE3, CD56, SALL4, Glypican-3, SOX-2, cytokeratin AE1AE3, CD56, and CD99 (Figure 4).