PMC6113981_01
Endoscopic images of Case 1. Multiple white spots are seen in the gastric fornix (a) and body (b). Magnifying endoscopy observation (c) and blue laser imaging (d) show deposition of slightly elevated, round, white substance and microvasculature on its surface, which are consistent with reported features of white globe appearance.
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figure1
Endoscopy revealed multiple white spots in the fornix (Figure 1a) and body (Figure 1b) of the stomach. Magnifying endoscopy observation (Figure 1c) and blue laser imaging (Figure 1d) showed a slightly elevated, round, white substance.
Pathology images of Case 1. Biopsied specimen reveals cystic dilatation of the gastric fundal gland that had a 400 mum diameter (a, b). Parietal cell protrusion is also noted (c, arrows) along with dilated duct (c, asterisk).
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Biopsy from the gastric mucosa that contained white spots revealed cystic dilation of the gastric fundal gland with a 400 mum diameter (Figure 2a, b). Parietal cell protrusion was also noted (Figure 2c, arrows).
PMC6113981_02
Endoscopic images of Case 2. Multiple white spots are identified in the gastric fornix (a, arrows) and body (b, post-indigo carmine spraying). Magnifying endocopy observation (c) and blue laser imaging (d) show small, round, white deposits.
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Esophagogastroduodenoscopy revealed multiple white spots in the gastric fornix (Figure 3a, arrows), body (Figure 3b, post-indigo carmine spraying) and antrum. Magnifying endoscopy observation (Figure 3c) and blue laser imaging (Figure 3d) showed small, round, white deposits that were similar to the substances observed in case 1.
Pathology images of Case 2. The biopsied specimen shows cystic dilatation of the gastric fundal gland of approximately 600 mum diameter (a, b). Parietal cell protrusions and dilated glands forming microcysts are also seen (c).
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Cystic dilation of the gastric fundal gland was identified in the biopsied specimen obtained from the white spots, which contained debris in the dilated duct (Figure 4a, b). In addition, parietal cell protrusions and dilated glands forming microcysts were present (Figure 4c).