PMC4276567_01
Pharmacokinetic and clinical data from case report 1. CSF, cerebrospinal fluid; KPS, Karnofsky performance status.
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F4
The concentration of CSF 3 hours after administration was 0.464 ng/ml BIBW 2992 BS, which is equivalent to a concentration of approximately 1 nMol afatinib in the CSF (Fig. 4).
PMC4276567_02