PMC8559647_01
Wilms' tumor composed of tubuloglandular and mesenchymal component. A) (40x, H&E stain). B) (200x, H&E stain).C) rosette- like structure (400x, H&E stain). D) mesenchymal stroma (400x, H&E stain)
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F1
In abdominal and pelvic computed tomography (CT) scan with and without contrast, solid and hypodense mass involving the upper half right kidney was detected with approximately 128x100 mm in diameter (figure1).
Immunohistochemical staining A) WT1 B) WT1 (repeat)
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F2
In the light microscopic examination, the tumor was composed of tubular and rosette-like structures covered by simple to pseudo-stratified columnar epithelium with elongated, vesicular nuclei with acidophilic cytoplasm, occasionally with intraluminal papillary projection, enclosed in fascicular mesenchymal stroma, fibrous and hyalinized areas (figure2).
Immunohistochemical staining A) Chromogranin B) Synaptophysin C) EMA D) CK E) CD10 F) HMB45 G) CD 56
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F3
WT1, CD10, CD99, synaptophysin, chromogranin was done. WT1 (with twice repeat) was non-specific (figure 3), EMA was positive and other markers were negative (figure 4).