PMC4860924_01
Growth in anterior region of lower jaw
JOMFP-20-163a-g001.jpg
PMC4860924_01_JOMFP-20-163a-g001.jpg
F1
Medical College and Hospital, Faridkot with a chief complaint of growth in the lower jaw [Figure 1]. Medical history of the patient revealed no relevant association with the lesion.
Orthopantomogram showing radiolucent area in lower jaw
JOMFP-20-163a-g002.jpg
PMC4860924_01_JOMFP-20-163a-g002.jpg
F2
The patient was advised orthopantomography and computed tomography (CT) scan [Figures 2 and 3].
Computed tomography showing erosion of labial and lingual cortices in the mandible
JOMFP-20-163a-g003.jpg
PMC4860924_01_JOMFP-20-163a-g003.jpg
F3
The patient was advised orthopantomography and computed tomography (CT) scan [Figures 2 and 3].
(a) Photomicrograph of dysplastic epithelium showing cellular-nuclear pleomorphism and nuclear hyperchromatism (H&E stain, x40), (b) The dysplastic epithelium is seen invading the underlying connective tissue in the form of nests and islands (H&E stain, x40), (c and d): High power view of the tumor islands showing cellular-nuclear pleomorphism and nuclear hyperchromatism with mitotic figures suggestive of moderately differentiated squamous cell carcinoma (H&E stain, x400)
JOMFP-20-163a-g004.jpg
PMC4860924_01_JOMFP-20-163a-g004.jpg
F4
The incisional biopsy of the lesion showed dysplastic epithelium with epithelial cells showing distinct nuclear pleomorphism, presence of mitotic activity, including atypical mitotic figures and premature keratinization [Figure 4a]. The dysplastic epithelial islands were seen invading the connective tissue [Figure 4b]. The histopathological findings were suggestive of moderately differentiated (G2) SCC [Figure 4c and d].