PMC2824745_01
Unenhanced CT scan showing a 5.4 x 7.0 cm, homogenous, low-density (27 HU) mass of the left adrenal.
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F1
Ultrasonography showed a 5.4 x 7.0 cm mass on the left adrenal gland, which was confirmed by unenhanced CT scan a size of 5.4 x 7.0 cm well-shaped, homogenous, and low-density (27 HU) tumor (Figure 1).
Histological section of the primary IDC of the right breast (2A) and the adrenal metastatic disease(2B, 2C). The tumor cells are arranged in solid nests or cords with infiltrative growth pattern in the primary IDC (2A; H & E 10 x), which has also been shown in the adrenal metastatic lesion (2B; H & E 10 x) with vaying size of oval cells showing eosinophilic cytoplasm and prominent small nucleoli (2C; H & E 40 x).
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F2
Postoperative histopathological examination (confirmed by the department of pathology of this institute) revealed an original grade II invasive ductal carcinoma(Figure 2A) with a size of 5.0 x 3.0 x 3.0 cm. IDC of the breast as same characteristics of the tumor cells were observed (Figure 2B, C). Immunohistochemical staining on metastasized adrenal tumor showed negative for estradiol, progesterone receptors and P53, but positive for C-erbB-2 (Figure 3A), gross cystic disease fluid protein-15 (GCDFP-15) (Figure 3B) and mammaglobin (Figure 3C).
Immuno - staining of the adrenal metastatic disease (IHC, 20 x). The tumor cells show positivity for C-erbB2 (3A), GCDFP-15 (3B) and Mammaglobin (3C).
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F3
IDC of the breast as same characteristics of the tumor cells were observed (Figure 2B, C). Immunohistochemical staining on metastasized adrenal tumor showed negative for estradiol, progesterone receptors and P53, but positive for C-erbB-2 (Figure 3A), gross cystic disease fluid protein-15 (GCDFP-15) (Figure 3B) and mammaglobin (Figure 3C).