PMC4936818_01
PET-CT of the patient.. Notes: (A) CT of the patient. (B) PET of the patient. (C) PET-CT of the patient. (D) Multum in parvo.. Abbreviations: PET, positron emission tomography; CT, computed tomography; L, left; R, right.
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Serum lactate dehydrogenase was elevated to 1,500 IU/L (normal 200-460 IU/L), and other laboratory data showed anemia. 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning showed that accumulation of FDG was observed in the soft tissue lump near the lumbar vertebra 1-5, considering malignant tumor (Figure 1).
Biopsy of soft tissue lesions: (A) HE staining, (B) ALK staining, and (C) CD30 staining.. Note: Magnification for all images: 400x.. Abbreviations: HE, hematoxylin and eosin; ALK, anaplastic large cell lymphoma kinase.
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These cells were positive for ALK-1, CD30, TIA-1, GranzymeB, CD4, CD8, and Ki67 (90%+) and negative for CD3, CD5, CD20, CD10, cytokeratin (CK), TdT, HMB-45, epithelial membrane antigen (EMA), and pan-CK (Figure 2).