PMC5457921_01
The electrocardiograms (ECGs) of patient 1. The ECG obtained prior to admission showed a sinus rhythm. There were no premature ventricular contractions (VPcs). At 23 minutes after the administration of LDV/SOF, the patient experienced dizziness, and ECG monitoring demonstrated VT for approximately 20 seconds. Holter ECG monitoring results then remained normal for 5 days after treatment.
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The QTc ratio was 438 mm (Fig. 1). Twenty-three minutes after taking the LDV/SOF, the patient experienced dizziness and ECG monitoring demonstrated VT for approximately 20 seconds (Fig. 1). The findings of an echocardiogram, Holter monitoring, and heart rate monitoring 5 days after treatment were all normal (Fig. 1).
PMC5457921_02
The electrocardiograms (ECGs) of patient 2. An ECG obtained upon admission showed sinus rhythm. ECGs recorded 2, 5, and 10 days after treatment are shown. VT developed 2 days after the treatment. LDV/SOF administration was continued, and 5 days later, VT developed again. After discontinuation of LDV/SOF for 10 days, no arrhythmias were detected.
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She was discharged from the hospital 20 days after admission (Fig. 2).