PMC5409851_01
Preoperative computed tomography. (A) The tumor in the left hepatic lobe showed enhancement from its periphery, with penetration of the hepatic artery and the dilatation of the peripheral biliary duct in the arterial phase (white arrow). Liver cysts were observed in segments 5 (black arrow). (B) Tumor enhancement was prolonged in the equilibrium phase.
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In early-phase imaging, the tumor showed enhancement at the tumor periphery; this was prolonged on late-phase imaging (Fig. 1).
Immunohistochemical findings of the tumor. (A) Hematoxylin and eosin staining: The tumor was composed of small glands showing antler-like and anastomosing patterns with abundant fibrous stroma. The tumor was positive for cytokeratin (CK) 7 (B), CK19 (C), and epithelial cell adhesion molecule (D).
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Immunohistochemical examination revealed positive expression of cytokeratin (CK) 7, CK19, and EpCAM (Fig. 2).