PMC4242703_01
PMC4242703_02
Axial computed tomography study of the brain.. Notes: Minute cortical and subcortical calcifications located in bilateral frontal lobe.
ndt-10-2249Fig1.jpg
PMC4242703_02_ndt-10-2249Fig1.jpg
f1-ndt-10-2249
A computed tomography brain study revealed a few bilateral cortical convolutions and microscopic subcortical calcifications (Figure 1), especially in the frontal regions.
Axial Spin-Echo T2-weighted (A, C) and T1-weighted (B, D) magnetic resonance imaging study of the brain.. Notes: Developmental abnormalities (polymicrogyria) in the frontal opercular cortex bilaterally, more evident on the left side.
ndt-10-2249Fig2.jpg
PMC4242703_02_ndt-10-2249Fig2.jpg
f2-ndt-10-2249
Magnetic resonance imaging (MRI) of the brain revealed smooth opercula and frontal (both superior and middle frontal circumvolutions) cortex (Figure 2A-D) and a "cobblestone" appearance in both frontal cortices (Figure 3).
Spin-Echo T2-weighted sagittal projections on magnetic resonance imaging study of the brain.. Notes: A "cobblestone" appearance is evident in the bilateral frontal opercular region.
ndt-10-2249Fig3.jpg
PMC4242703_02_ndt-10-2249Fig3.jpg
f3-ndt-10-2249
Magnetic resonance imaging (MRI) of the brain revealed smooth opercula and frontal (both superior and middle frontal circumvolutions) cortex (Figure 2A-D) and a "cobblestone" appearance in both frontal cortices (Figure 3).
Electroencephalogram showing diffusely deregulated cerebral electrical activity together with ubiquitous fast paroxysms, prevalent in the left temporal area.
ndt-10-2249Fig4.jpg
PMC4242703_02_ndt-10-2249Fig4.jpg
f4-ndt-10-2249
An electroencephalogram performed when she was 21 years old showed diffusely deregulated cerebral electrical activity together with ubiquitous fast paroxysms, prevalent in the left temporal area (Figure 4).