PMC3262543_01
Patient's left forearm with large exophytic tumor and two satellite tumors.
DERMATOLOGY2011-634042.001.jpg
PMC3262543_01_DERMATOLOGY2011-634042.001.jpg
fig1
Two smaller satellite nodules were seen along the mid dorsal forearm, each measuring 2.0 x 2.0 cm (Figure 1).
H&E staining of the tumor shows a dense perivascular and band-like monomorphous infiltrate composed of markedly atypical, large, pleomorphic epithelioid cells, along with immature cells resembling immunoblasts.
DERMATOLOGY2011-634042.002.jpg
PMC3262543_01_DERMATOLOGY2011-634042.002.jpg
fig2
It showed a polypoid lesion characterized by a dense perivascular and band-like monomorphous infiltrate composed of markedly atypical, large, pleomorphic epithelioid cells, as well as immature cells resembling immunoblasts (Figures 2 and 3).
H&E staining of the tumor shows a dense perivascular and band-like monomorphous infiltrate composed of markedly atypical, large, pleomorphic epithelioid cells, along with immature cells resembling immunoblasts.
DERMATOLOGY2011-634042.003.jpg
PMC3262543_01_DERMATOLOGY2011-634042.003.jpg
fig3
It showed a polypoid lesion characterized by a dense perivascular and band-like monomorphous infiltrate composed of markedly atypical, large, pleomorphic epithelioid cells, as well as immature cells resembling immunoblasts (Figures 2 and 3).
Histological image of the tumor stained to show expression of the CD30 surface marker on the atypical lymphoid cells.
DERMATOLOGY2011-634042.004.jpg
PMC3262543_01_DERMATOLOGY2011-634042.004.jpg
fig4
Over 75% of the atypical lymphoid cells expressed CD30 (Figure 4), but not ALK1 (Figure 5) and EMA (Figure 6), which led to the diagnosis of CD30+ primary cutaneous anaplastic large cell lymphoma (CD30+ PCLCL).
Histological image of the tumor that shows absence of the ALK-1 protein on the atypical lymphoid cells.
DERMATOLOGY2011-634042.005.jpg
PMC3262543_01_DERMATOLOGY2011-634042.005.jpg
fig5
Over 75% of the atypical lymphoid cells expressed CD30 (Figure 4), but not ALK1 (Figure 5) and EMA (Figure 6), which led to the diagnosis of CD30+ primary cutaneous anaplastic large cell lymphoma (CD30+ PCLCL).
Histological image of the tumor that shows absence of the EMA surface marker on the atypical lymphoid cells.
DERMATOLOGY2011-634042.006.jpg
PMC3262543_01_DERMATOLOGY2011-634042.006.jpg
fig6
Over 75% of the atypical lymphoid cells expressed CD30 (Figure 4), but not ALK1 (Figure 5) and EMA (Figure 6), which led to the diagnosis of CD30+ primary cutaneous anaplastic large cell lymphoma (CD30+ PCLCL).