PMC7527899_01
(a) Full-thickness macular hole (FTMH) in the right eye before surgery. Hole diameter equal to 475 microm. (b) Unclosed FTMH in the right eye 1 month after vitrectomy. Poor image quality caused by the rest of SF6 gas. Hole diameter equal to 452 microm. (c) Closed FTMH 3 months after secondary vitrectomy in the right eye. (d) Postoperative microperimetric results of the right eye. (e) OCT image of macula of the healthy, left eye. (f) Normal microperimetry result of the left eye. Postoperative FAZ measurement using a nonflow software. Foveal avascular zone (FAZ) of the right eye (g) twice operated, increased significantly compared to FAZ of the healthy, left eye (h).
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fig1
ILM was performed. It was a successful surgery, and V-shape closure of FTMH was received (Figure 1).
PMC7527899_02
Left eye of the patient no. 2. (a) FTMH before surgery. Diameter equal to 485 microm. (b) Unclosed FTMH after vitrectomy with diameter 765 microm. (c) Closed FTMH with intraretinal cysts, 6 months after secondary PPV. (d) Postoperative microperimetric results. FTMH of the right eye of patient no. 2 before (e) and after primary, successful pars plana vitrectomy (PPV) (f). (g) Postoperative microperimetric results of the right eye. (h) Postoperative FAZ of left eye, operated twice. Nonflow area: 0.604 mm2, BCVA 0.1. (i) Postoperative foveal avascular zone (FAZ) of the right eye after one vitrectomy, nonflow area: 0.363 mm2, BCVA equal to 0.8.
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fig2
Two months later, the secondary vitrectomy was performed with anatomical success, and V-shape closure was observed (Figure 2).
PMC7527899_03
(a) Preoperative FTMH of the right eye of patient no. 3 with diameter 765 microm. (b) Unclosed FTMH after primary vitrectomy, 940 microm of diameter. (c) After secondary vitrectomy with atrophy. (d) Postoperative microperimetric results, BCVA 0.05. FTMH of the left eye with diameter 660 microm before (e) and after primary, successful vitrectomy (f). (g) Postoperative microperimetric results, BCVA 0.1. (h) Postoperative foveal avascular zone (FAZ) of the right eye, nonflow area: 1.856 mm. (i) Postoperative FAZ of the left eye, nonflow area: 0.557 mm2.
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fig3
Seven months later, secondary vitrectomy was performed and ended with V-shape closure of FTMH (Figure 3). 11 months observation of the right eye showed the macular atrophy and following functional results: BCVA was 0.05, AT in microperimetry was 12.8, fixation was relatively unstable (P1 = 42%, P2 = 85%), and eccentric fixation was found.
PMC7527899_04
(a) Preoperative FTMH of the left eye of patient no. 4 with diameter 588 microm. (b) Unclosed FTMH 1 month after vitrectomy, hole diameter equal to 726 microm. (c) V-shaped closure of FTMH after secondary vitrectomy. (d) Postoperative microperimetric results of the left eye. (e) OCT image of macula of the healthy, right eye. (f) Normal microperimetry result of the right eye. (g) Postoperative FAZ of the left eye, nonflow area: 0.818 mm2. (h) FAZ of the right eye, nonflow area: 0.653 mm2.
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fig4
V-shape closure of FTMH was received, and BCVA was improved to 0.2 (Figure 4).