PMC7784227_01
Microscopic findings of the resected appendix showed tumour cells infiltration into the muscularis propriae, with two distinct components identified (H&E, 40x).
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Both tumour groups (Figures 1 and 2) encompass >30% of tumour volume each.
First component: nests of tumour cells exhibiting uniform, round nuclei with salt and pepper chromatin (arrow head). Second component: goblet cells displaying univacuolated cytoplasm and peripherally compressed nuclei (arrow) (H&E, 200x).
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Both tumour groups (Figures 1 and 2) encompass >30% of tumour volume each.
Immunohistochemical findings revealed both components are positive for synaptophysin (A). However, only the goblet cells are positive for CK20 (B) (400x).
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The Ki-67 proliferation index is <2% (Figure 3).