PMC8047926_01
Right middle lobe (RML) obstruction associated with a synchronous endobronchial carcinoid and aspergillosis. (a) 27 x 21 mm lung mass was found in the RML on the initial chest computed tomography scan. (b) Initial bronchoscopy showed fibrosis and stenosis of the lateral segment of the RML with abundant mucoid material. (c) The mass had increased in size to 66 x 39 mm 3 months later, and caused obstructive pneumonia in the RML. (d) Acute-angle branching, septate, and narrow Aspergillus hyphae indicate aspergillosis. (e) Hematoxylin and eosin staining showing the carcinoid tumor. (f) CD56 immunostaining of the carcinoid tumor.
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PMC8047926_01_10.1177_2050313X211009426-fig1.jpg
fig1-2050313X211009426
Chest CT revealed a 27 x 21 mm lung mass on the right middle lobe (RML) (Figure 1(a)). A bronchoscopic examination revealed fibrosis and stenosis of the lateral segment of the RML, with abundant mucoid material (Figure 1(b)). A chest CT showed RML atelectasis and enlargement of the perivascular area lymph node, with a 66 x 39 mm mass-like lesion (Figure 1(c)). Unexpectedly, a microscopic examination of the biopsy revealed an RML bronchial carcinoid tumor and aspergillosis (Figure 1(d) and (e)). The tumor cells stained positive for neuroendocrine markers, including CD56 (Figure 1(f)), synaptophysin, and chromogranin.