PMC6349631_01
Photographic progression of patient's skin lesions at the (A) anterior left thigh and (B) lateral left hip. Photographs were taken at initial presentation to radiation oncology, after 5 weeks of pralatrexate therapy post-radiation therapy, and 7 weeks after discontinuation of pralatrexate.
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At the next follow-up visit, the patient had completed 5 weeks of pralatrexate therapy but developed progressive ulcers of the previously irradiated skin lesions and grade 3 oral mucositis (Figs 1A-B). One month later, the patient reported that the skin lesions were healing well (Figs 1A-B).
(A) Simulation set-up photo showing anterior left thigh and lateral left hip lesions. (B) Digitally reconstructed radiograph demonstrating anterior field with tumor outlined in red.
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Two slightly oblique antero-posterior fields were used to include both the left thigh and hip lesions with a 2 cm margin (Fig 2).