PMC9873306_01
Images of computed tomography (CT). (A) CT revealing a mass in orbit, some of which seem to extend into the cranial cavity. (B) The bone window showing compressive displacement of the adjacent bone and widened supraorbital fissure (two-way arrow).
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F1
The inner bone wall of the left orbit was thinner than before, with compressive displacement of the adjacent bone and widening of the supraorbital fissure (Figure 1).
Preoperative image of magnetic resonance imaging (MRI). (A-D) MRI demonstrating a circumscribed mass that extended into the left cavernous sinus (red circle), with a slightly inhomogeneous hypointense signal on T1WI and a slightly inhomogeneous hyperintense signal on T2WI. Meanwhile, it shows an inhomogeneous isointense signal on fluid-attenuated inversion recovery (FLAIR) and a hypointense signal on diffusion-weighted imaging (DWI). (E) The mass showed clear and mild inhomogeneous enhancement after Gd injection. (F) The mass located above the optic nerve (red arrows), which was intact and not pressed (white arrow).
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F2
Meanwhile, the mass showed a hypointense signal on diffusion-weighted imaging (DWI) and a low value of apparent diffusion coefficient (ADC), with apparent and inhomogeneous enhancement after gadolinium (Gd) injection (Figure 2).
Postoperative image of MRI. (A-C) Images of T1WI, T2WI, and Flair, and (D) images after gadolinium (Gd) injection were performed 3 months after the operation, respectively, showing no recurrence.
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F3
An MRI performed 3 months after surgery showed no tumor persistence (Figure 3).
Image of pathology. (A) A biphasic pattern of Antoni A and Antoni B (hematoxylin and eosin, x 400). (B) Diffusely and strongly positive immunoreactivity for S100 (immunohistochemistry for S100, x 200). (C) Positive immunoreactivity for SOX10 (immunohistochemistry for SOX10, x 200). (D) Less than 1% positive immunoreactivity for KI67 (immunohistochemistry for KI67, x 200).
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F4
The nuclei of those cells showed positive immunoreactivity for SOX10 and less than 1% of the nuclei showed positive immunoreactivity for KI67 (Figure 4).