PMC8159635_01
CK and TSH values over time in patient with treated hypothyroidism.
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TSH level had decreased to 183 mIU/L with a decline in CK level to 3203 U/L (Figure 1), and improvement in his proximal strength was observed to grade 5/5 power. There was persistent distal lower limb weakness with bilateral footdrop.
Serial nerve conduction values over time. (a) Sural nerve amplitude (muV). (b) Median distal motor latency (ms).
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Congruently, with physical findings, his repeat NCS revealed some improvement in sensory amplitudes and conduction velocities in patient's arms; however, motor and sensory responses in his legs remained largely absent (Figure 2).  Figure 2(a) demonstrates the trend of sural sensory nerve amplitudes, whilst Figure 2(b) depicts median distal motor nerve latency over three studies performed at baseline, 3 months, and 12 months after diagnosis.