PMC5385583_01
Axial T2-weighted (top two slices) and T1-weighted (bottom two slices) MRI of the head shows bilateral cortical dysplasia with fairly symmetric thickening in both frontal lobes (large arrows), involving the middle and inferior frontal gyri particularly with some extension to the precentral gyri. There is cortical thickening seen in the parietal lobes and upper insula posteriorly (small arrows).
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Inter-ictal EEG recordings during wakefulness (top) and sleep (bottom). The top EEG is displayed in a longitudinal bipolar montage and the bottom in a referential montage. The awake EEG shows multiple generalized spikes, polyspikes, and polyspikes-and-waves. The asleep EEG shows polyspikes (*) and polyspikes-and-wave complexes (**). All EEG electrodes were placed using the international 10-20 system of electrode placement. Technical parameters; low frequency filter 1 Hz, high frequency filter 70 Hz, notch off, sensitivity 7 muV/mm, time base 30 mm/s, sampling rate 500 Hz.
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She had frequent generalized spikes, polyspikes, polyspikes-and-waves, and frequent electrographic seizures during wakefulness without apparent clinical findings (Fig. 2). Her generalized spikes, polyspikes, and polyspikes-and-waves were augmented during sleep (Fig. 2).