PMC8529210_01
Serial diffusion-weighted images (DWI) of brain magnetic resonance imaging (MRI). No abnormalities were detected on DWI obtained 5 years prior to the clinical onset (A). DWI acquired 6 months before clinical onset shows a very small hyperintensity in the right parietal cortex (arrow) (B). DWI obtained 2 months before clinical onset reveals a slight increase in the abnormal lesion in the right parietal cortex and new lesions in the right frontal lobe (arrow) (C). DWI obtained 3 months after clinical onset demonstrates the expansion of the hyperintense region to a broad range of the cerebral cortex (D). Arrowheads shown in (A-C) possibly represent the artifacts in the temporal lobe cortex.
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F1
Although no abnormalities were detected on MRI performed due to a slight headache 5 years prior (Figure 1A), DWI demonstrated very small hyperintensity in the right parietal cortex (Figure 1B, arrow). Follow-up MRI performed 4 months later revealed new lesions in the right frontal lobe, in addition to a slight enlargement of the previous lesion (Figure 1C, arrows). DWI demonstrated expansion of the hyperintense area to a broad range of the cerebral cortex (Figure 1D).