PMC9748654_01
Endoscopic image of the tumor showing the high-frequency electrical snare lifting the clamped tumor.
etm-25-01-11705-g00.jpg
PMC9748654_01_etm-25-01-11705-g00.jpg
f1-ETM-25-1-11705
After normal saline (with epinephrine and indigo carmine) was injected into the base to lift the tumor, the tumor was completely excised with a high-frequency electrical snare and the wound surface was clamped with metal for hemostasis (Figs. 1 and 2).
Endoscopic image of the tumor showing the basal surface of the resected tumor (the basal surface area is about 1.5x1 cm).
etm-25-01-11705-g01.jpg
PMC9748654_01_etm-25-01-11705-g01.jpg
f2-ETM-25-1-11705
After normal saline (with epinephrine and indigo carmine) was injected into the base to lift the tumor, the tumor was completely excised with a high-frequency electrical snare and the wound surface was clamped with metal for hemostasis (Figs. 1 and 2).
Histopathological appearance of inverted hyperplastic polyp showing the submucosal 'inverted' glands with smooth muscle bundles encircling the 'inverted' glands or surrounding a single gland. Some glands were similar to the normal inherent glands in size and some were saccular-dilated with visible eosinophilic secretion in the glandular cavity (magnification, x16; hematoxylin and eosin staining; scale bar=1,000 microm).
etm-25-01-11705-g02.jpg
PMC9748654_01_etm-25-01-11705-g02.jpg
f3-ETM-25-1-11705
Scattered infiltration of lymphocytes or formation of lymphoid follicles were seen in the interstitium (Figs. 3 and 4).
Partial enlarged view of Fig. 3 showing that the hyperplastic smooth muscle bundles surrounded the lobules composed of glands and the glands within the polyp had expanded sacculi (magnification, x200; hematoxylin and eosin staining; scale bars=50 microm).
etm-25-01-11705-g03.jpg
PMC9748654_01_etm-25-01-11705-g03.jpg
f4-ETM-25-1-11705
Scattered infiltration of lymphocytes or formation of lymphoid follicles were seen in the interstitium (Figs. 3 and 4).
Immunohistochemical staining of inverted hyperplastic polyp showing the diffuse and strong cytoplasmic expression of glandular MUC-5AC in the polyp (EnVision; magnification, x200; scale bar=50 microm).
etm-25-01-11705-g04.jpg
PMC9748654_01_etm-25-01-11705-g04.jpg
f5-ETM-25-1-11705
Technologies, Inc.) overnight at 4 C from EnVision Systems (Agilent Technologies, Inc.) showed diffuse strong positive expression of MUC-5AC and MUC-6 in the cytoplasm of the polyp glands (Figs. 5 and 6) and positive expression of SMA and Desmin in the muscular layer of mucosa and the smooth muscle bundle of interstitial tissue of the polyps (Fig. 7). The staining further showed negative expression of CD10, CDX-2 and MUC-2 and the Ki-67 proliferating index was less than 2% of the glands in the polyps.
Immunohistochemical staining of inverted hyperplastic polyp showing the diffuse and strong cytoplasmic expression of glandular MUC-6 in the polyp (EnVision; magnification, x200; scale bar=50 microm).
etm-25-01-11705-g05.jpg
PMC9748654_01_etm-25-01-11705-g05.jpg
f6-ETM-25-1-11705
Technologies, Inc.) overnight at 4 C from EnVision Systems (Agilent Technologies, Inc.) showed diffuse strong positive expression of MUC-5AC and MUC-6 in the cytoplasm of the polyp glands (Figs. 5 and 6) and positive expression of SMA and Desmin in the muscular layer of mucosa and the smooth muscle bundle of interstitial tissue of the polyps (Fig. 7). The staining further showed negative expression of CD10, CDX-2 and MUC-2 and the Ki-67 proliferating index was less than 2% of the glands in the polyps.