PMC6000855_01
Liver biopsy 6 months after OLT showing hypertrophic macrophages containing iron and slight accumulation of hemosiderin in hepatocytes (Perls' stain).
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A liver biopsy performed at that period revealed numerous hypertrophic, iron-loaded macrophages and severe bile duct damage and loss, consistent with early mild chronic rejection (Figure 1).
Liver biopsy 18 months after OLT demonstrating heavy granular iron deposition in hepatocytes and macrophages corresponding to hemosiderosis (Perls' stain).
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Iron staining showed significant accumulation of iron in macrophages and hepatocytes, consistent with marked hemosiderosis (Figure 2).