PMC3794623_01
Pathology reports. (a) Atypical lymphoid cells infiltrated diffusely into the superficial and deep dermis. (b) Most of the atypical lymphoid cells were positive for CD3 (x200). (c) Most of the atypical lymphoid cells were positive for CD4 (x200). (d) Only a small portion of them were positive for CD8 (x200). (e) Only a small portion of them were positive for CD79a (x200). (f) Only a small portion of them were positive for CD56 (x200). (g) All negative for CD30 (x200). (h) Negative for CD3 (x40). (i) Negative for CD20 (x40) showed inflammation change without residual T-cell lymphoma.
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fig1
Many medium- to large-sized atypical lymphoid cells infiltrated diffusely into the superficial and deep dermis (Figure 1(a)). Most of the atypical lymphoid cells were positive for CD3 (Figure 1(b)) and CD4 (Figure 1(c)). Only a small portion of them were positive for CD8 (Figure 1(d)), CD79a (Figure 1(e)), and CD56 (Figure 1(f)). They were all negative for CD30 (Figure 1(g)).
Irradiation techniques. (a) Helical irradiation of the total skin (HITS) with dose painting technique for total skin irradiation (white arrow indicates dose painting on the previous irradiation area). (b) The dose volume histograms (DVHs) of the target and individual organs at risk (OARs). (c) The hypothetical bolus was placed on the skin surface with 1-1.5 cm. A central core complete block (CCCB) 2.5 cm away from PTV in HITS planning. (d) The locations of radiochromic EBT2 film on the body surface.
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fig2
A central core complete block (CCCB) 2.5 cm away from PTV in HT planning system was used to restrict the photon beams to be an oblique incidence for increasing the superficial dose and reducing the internal organ dose (Figure 2(c)).  The starting day in first period, 128 EBT2 films were measured (Figure 2(d)).
Calibration curve of radiochromic EBT2 film.
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fig3
The calibration curve was fitted using a polynomial function with the pixel value (PV) for each measurement film converted to dose accordingly (Figure 3).