PMC4789418_01
Bone marrow aspiration cytology (H&E stain, magnification 400x) shows hypercellular bone marrow with proliferating blasts replacing most of the normal bone marrow.
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fig1
This revealed a hypercellular marrow with overall 5% myeloblasts with megaloblastic changes in the red cells and myeloid series and normal appearing megakaryocytes (Figures 1 -3).
Bone marrow aspiration cytology (W&G stain, magnification 1000x) shows medium to large blast cells replacing normal bone marrow cellularity. Dysplastic granules and occasional vacuoles are observed.
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fig2
This revealed a hypercellular marrow with overall 5% myeloblasts with megaloblastic changes in the red cells and myeloid series and normal appearing megakaryocytes (Figures 1 -3).
Bone marrow aspirate flow cytometry showing increased number of blasts and left shifted granulopoiesis.
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fig3
This revealed a hypercellular marrow with overall 5% myeloblasts with megaloblastic changes in the red cells and myeloid series and normal appearing megakaryocytes (Figures 1 -3).
Peripheral blood smear: (W&G stain) show circulating blasts, dysplastic neutrophils, and nucleated red blood cells.
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fig4
The peripheral blood showed marked anisocytosis with moderate normocytic normochromic anemia and left shifted myeloid series and thrombocytopenia (Figure 4).