PMC5469202_01
Evolution of UTC, salivary F and serum F during follow-up,
normalized by the upper limit normal range (ULNR)
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Fig1
The patient's midnight salivary cortisol level was elevated (salivary F = 0.2-2.3 mug/dL - RR < 0.12 mug/dL), as measured using a manual ELISA Millipore kit (Fig. 1), and plasma ACTH measurements were within the reference interval at 14 pg/ml (reference values = 10-46 pg/ml) by chemiluminescence immunoassay (Immulite 2000/Siemens Healthcare Diagnostics).
MRI sequences during follow-up. (A) May/2007: coronal view on T 1-weighted MRI of
the pituitary gland identified a heterogeneous solid macroadenoma
(1.9x1.8 cm of diameter - arrow). (B) August/2013: MRI after four years of
transsphenoidal surgery - questionable remnant tumor tissue or
arachnoid cyst (arrow)
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PMC5469202_01_40842_2015_2_Fig2_HTML.jpg
Fig2
Australia), although the serum PRL levels were normal. Abdominal CT showed normal adrenal glands and pituitary MRI exhibited a cystic lesion similar to the previous tumor tissue, but could also represent an arachnoid cyst (Fig. 2 A).   