PMC6381848_01
Serial panoramic radiograph monitoring the resolution of the lesion: (a) Orthopantomogram radiograph at the initial presentation; (b) 4 months after the first triamcinolone injection; (c) 8 months after the first triamcinolone injection; (d) 18 months from the initial injection
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F1
Orthopantomogram X-ray revealed a large, radiolucent, irregular lytic lesion measuring 2.5 cm x 3.2 cm and extending from the retromolar area of the lower right first molar to the ramus of the mandible with a radiolucent line, suggesting a pathological fracture [Figure 1]. Four months after the first injection, there was a significant reduction in the size of the lesion [Figure 1b], and complete healing with normal bone trabeculation was appreciated 18 months after the first injection.
Histological sections stained by routine hematoxylin and eosin stains by routine hematoxylin and eosin stains at (a and b) medium power; (c and d) at high power
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F2
The histiocytes were immunoreactive for S100 and CD1a proteins by standard immunohistochemical stains, thereby confirming the diagnosis of LCH [Figure 2].