PMC6619383_01
Breast carcinoma showing an adenocarcinoma with marked nuclear pleomorphism.. (H&E stain, X400 magnification).
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Ki67 staining showed a proliferation index of 20% ( Figure 1).
Prostatic adenocarcinoma.. (H&E stain, X400 magnification).
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The tumour cells had large nuclei, conspicuous nucleoli and abundant pale eosinophilic cytoplasm ( Figure 2).
PMC6619383_02
Breast infiltrating duct carcinoma (H&E stain, X200 magnification).
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  The right breast histopathological assessment.  Histopathological examination showed an infiltrating duct carcinoma ( Figure 3), with a Nottingham combined histopathological grade of 1/3 (tubules 1, pleomorphism 2 and mitoses 1).
Oestrogen receptors diffusely expressed in the breast carcinoma (estrogen receptor (ER) immunohistochemistry, X200 magnification).
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Figure 4). Foci of low-grade cribriform ductal carcinoma in situ were also evident ( Figure 5).
Breast cribriform ductal carcinoma
in situ (DCIS) (H&E stain, X200 magnification).
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Figure 4). Foci of low-grade cribriform ductal carcinoma in situ were also evident ( Figure 5).
Invasive prostatic adenocarcinoma (H&E stain, X200 magnification).
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  Prostate biopsy.  Biopsy results showed an invasive prostatic adenocarcinoma ( Figure 6), with a modified Gleason score of 9, and grade group 5, which was infiltrating into skeletal muscle ( Figure 7).
Invasive prostatic adenocarcinoma infiltrating into skeletal muscle (H&E stain, X200 magnification).
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  Prostate biopsy.  Biopsy results showed an invasive prostatic adenocarcinoma ( Figure 6), with a modified Gleason score of 9, and grade group 5, which was infiltrating into skeletal muscle ( Figure 7).