PMC4984831_01
Sheet-like, worm-eaten bone destruction area is shown in the left-sided distal radius X-ray and localized bone cortex is completely or partially discontinuous.
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The localized bone cortex was completely or partially discontinuous (Figure 1).
MRI and enhanced MRI: coronary, lateral, sagittal axis.. Notes: MRI shows sheet-like bone destruction area in the left-sided radius, completely or partially discontinuous localized bone cortex, and adjacent soft tissue masses with low-signal intensity on T1-weighted images (A). T2-weighed images show heterogeneous high signal of (B) coronary axis, (C) lateral axis. Enhanced scanning shows heterogeneous enhancement of (D) coronary axis, (E) lateral axis, (F) sagittal axis.. Abbreviation: MRI, magnetic resonance image.
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After 1 month, with aggravated pain, swelling of left-sided distal forearm, and progressive limited motion in the left wrist, the patient was admitted to our hospital and underwent Magnetic Resonance Imaging, which demonstrated a sheet-like bone destruction area in the left-sided radius, localized discontinuous bone cortex, and adjacent soft tissue masses, hinting at primary bone malignancy (Figure 2).
Pathology and immunophenotyping of primary bone diffuse large B-cell lymphoma, non-GCB (x400). (A) CD20+, (B) CD5+, (C) PAX-5+, (D) MUM-1+, (E) Ki67+.. Abbreviation: non-GCB, non-germinal center B-cell-like.
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Immunochemical results showed CD20+, CD5+, PAX-5+, MUM-1+, CD3-, CD45RO-, CK-, vimentin-, myogenin-, CD30-, CD10-, Bcl-6-, and Ki67+ (70%), which demonstrated DLBCL, non-germinal center B-cell-like (non-GCB) (Figure 3).