PMC3919891_01
(A) T2-weighted sagittal and T1-weighted (B) axial and (C) sagittal gadolinium-enhanced MRI showing a ~15x28-mm spindle-shaped intramedullary mass located at the level of T12. (D) T2-weighted sagittal and T1-weighted (E) axial and (F) sagittal gadolinium-enhanced MRI demonstrating that the tumor tissue had been radically resected and a cavity had been formed. (G) Stained microscopic sections of the surgical specimen (hematoxylin and eosin; magnification, x50). (H) Immunohistochemical staining revealed a positive reaction to prostatic acid phosphatase (magnification, x100). MRI, magnetic resonance imaging.
OL-07-03-0717-g00.jpg
PMC3919891_01_OL-07-03-0717-g00.jpg
f1-ol-07-03-0717
The lesion was ~15 mm in diameter and ~28 mm in the vertical dimension (Fig. 1A). Following administration of gadopentetate meglumine, the well-demarcated lesion was enhanced (Fig. 1B and C). Microscopic examination of the surgical specimen revealed sheets and nests of cells with abundant cytoplasm and prominent nucleoli (Fig. 1G). The immunohistochemical staining results were negative for transcription factor-1, CK7, CK20, SPA, GFAP, CA19-9, Muc1, Muc4, p53 and Vim; however, a positive reaction to prostatic acid phosphatase was observed (Fig. 1H). A new MRI scan revealed that a cavity had formed (Fig. 1D-F) and, therefore, it was concluded that the tumor had been radically resected during surgery with no recurrence.
Single-photon emission computed tomography scan with 99mTc-MDP demonstrated that the patient exhibited systemic bone metastasis involving the bilateral ilium, right acetabular, right pubis and right femoral.
OL-07-03-0717-g01.jpg
PMC3919891_01_OL-07-03-0717-g01.jpg
f2-ol-07-03-0717
Furthermore, the patient accepted a single-photon emission computed tomography scan, which showed multiple bone metastatic lesions (Fig. 2).