PMC3254232_01
Preoperative CT scan showing a large, solid mass in the liver.
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fig1
Abdominal ultrasonography and computed tomography (CT) scans showed a solid mass in the right hepatic lobe, measuring 21 cm in its largest diameter, with possible colon and right kidney invasion, and vena cava compression (Figure 1).
PNET arising in the liver: diffuse sheet of uniform small round cells in a lobulated growth pattern, HE, 200x.
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fig2
On hematoxylin-eosin staining, a neoplastic process composed of sheets or lobules of small round cells, with little cytoplasm, and darkly staining, round or oval nuclei, was identified (Figure 2).
PNET arising in the liver: positive immunoexpression for vimentin, streptavidin-biotin, 200x.
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fig3
The immunohistochemical study of lesion revealed positive expression for vimentin (Vim 3B4:Figure 3) and CD99 (12E7:Figure 4), and negative immunostaining for desmin (D33), cytokeratin (AE1/AE3), and neuroblastoma protein (NB84).
PNET arising in the liver: the tumor cells show immunoreactivity for CD99, streptavidin-biotin, 200x.
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fig4
The immunohistochemical study of lesion revealed positive expression for vimentin (Vim 3B4:Figure 3) and CD99 (12E7:Figure 4), and negative immunostaining for desmin (D33), cytokeratin (AE1/AE3), and neuroblastoma protein (NB84).