PMC6476017_01
Histological picture of BBS. Small intestinal wall structure appears disrupted at low magnification (a). Closer examination reveals accumulation of brownish granules in the cytoplasm of smooth muscle cells, which occasionally degenerate appearing as single cells between muscle fibers (b). The epithelium, as well as the lamina propria, is normal (c).
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fig1
Histologic examination showed an abnormal accumulation of eosinophilic granules in the cytoplasm of smooth muscle cells with disruption of muscular fibers (Figure 1).
Radiological picture of BBS. Abdominal X-ray (a) and CT scan (b) show massive dilatation of the colon and the small intestine.
CRIS2019-4706592.002.jpg
PMC6476017_01_CRIS2019-4706592.002.jpg
fig2
Abdominal X-ray and CT evidenced severe intestinal dilatation (Figure 2), indicating the persistence of a severe impairment of colonic motility.