PMC9508361_01
series of pictures showing irregular ulcerations and encrustations on lips and upper and lower labial mucosa, bilateral buccal mucosa, dorsal and ventral surfaces of the tongue
PAMJ-42-184-g001.jpg
PMC9508361_01_PAMJ-42-184-g001.jpg
F1
Clinical findings: on clinical examination, irregular ulcerations and encrustations were noticed on the lips and diffuse erosions and ulcerations of variable sizes and irregular borders with peripheral oedema were noticed on the upper and lower labial mucosa, bilateral buccal mucosa, dorsal and ventral surfaces of the tongue (Figure 1).
H and E sections showing hyperplastic parakeratinized stratified squamous epithelium with broad elongated retepegs, the superficial epithelium shows intercellular edema, ulceration with suprabasillar split, and separation of parabasal layer of the epithelium
PAMJ-42-184-g002.jpg
PMC9508361_01_PAMJ-42-184-g002.jpg
F2
complete regression of lesions on lips and upper and lower labial mucosa, bilateral buccal mucosa, dorsal and ventral surfaces of the tongue
PAMJ-42-184-g003.jpg
PMC9508361_01_PAMJ-42-184-g003.jpg
F3
On the second follow-up, marked improvement of the lesions is noticed and the dose was tapered to 40 mg (Figure 3).