PMC9885181_01
Clinical images of palmoplantar pustulosis lesions on the sole. a Before vedolizumab treatment. b After 9-month administration of vedolizumab, the sole lesion improved.
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F1
A woman in her 50s, with a history of surgery for a root canal cyst and no smoking habit, had suffered from erythema, desquamation, vesicles, and pustules on her palms and soles for 4 months without any joint pain or other symptoms (Fig. 1a). Symptoms of PPP also improved after 9 months of vedolizumab treatment, leaving only mild keratosis on the soles (Fig. 1b).