PMC7586048_01
CT chest showing the distal esophageal tumor with obstruction.
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The initial diagnostic work up with computerized tomographic (CT) scans of the chest, abdomen and pelvis showed a 6 cm long distal esophageal mural wall thickening which was concerning for neoplasm (Fig. 1).
EGD showing narrowing of the distal esophagus.
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Esophagogastroduodenoscopy revealed narrowing of the distal esophagus (Fig. 2) located at 37 cm from the incisors.
Histologic stains showing submucosal stromal cells, marked fibrosis and multiple nerve bundles.
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The histologic examination of the specimen showed submucosal stromal fibrosis with multiple nerve bundles in a background of chronic inflammation, multinucleated giant cell reaction and lymphoid aggregates (Fig. 3).
Immunohistochemical stain positive for S100.
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Immunohistochemical analysis was positive for S-100 (Fig. 4), SOX - 10 and focal staining for CD 34.