PMC9289592_01
Upper endoscopy revealed two large, crater-like ulcerated lesions in the gastric fundus, ranging from 2.5 to 3cm (A, B)
CHSJ-48-01-128-fig1.jpg
PMC9289592_01_CHSJ-48-01-128-fig1.jpg
F1
Magnetic resonance images showing two wall thickening enhancing masses in the gastric fundus, measuring 1.45x1.9cm (A) and 2.8x2.4cm (B): The tumors are irregular, with restricted diffusion. (A) The mass exhibited a heterogeneous mild hypointensity on T2-weighted imaging. (B) On enhanced imaging, the lesion was unevenly enhanced
CHSJ-48-01-128-fig2.jpg
PMC9289592_01_CHSJ-48-01-128-fig2.jpg
F2
Hematoxylin and eosin sections of the endoscopic biopsy, at 40xmagnification: sheets or individual cells infiltrating the mucosa and submucosa of stomach. Tumor cells are pleomorphic rounded-epithelioid with hyperchromatic nuclei or vesicular chromatin and eosinophilic, prominent nucleoli. Some cells are dyscohesive, lacking pigmentation. No necrosis was identified in the examined mass.
CHSJ-48-01-128-fig3.jpg
PMC9289592_01_CHSJ-48-01-128-fig3.jpg
F3
Photomicrograph of endoscopic biopsy showing staining of large tumor cells, at 40xmagnification: (A) vimentin with cytoplasmatic expression; (B) S100 protein-nuclear and cytoplasmatic expression in tumor cells; (C)HMB45 antibody-cytoplasmatic positive tumor cells; (D) Melan A/MART1-membranous and cytoplasmatic staining in tumor; (40x).
CHSJ-48-01-128-fig4.jpg
PMC9289592_01_CHSJ-48-01-128-fig4.jpg
F4