PMC8346294_01
Multimodal fundus imaging. Optos fundus photos of the (a) right and (b) left eyes demonstrating placoid lesions in the macula and retinal periphery as well as peripheral punched-out scars in a Schlaegel line configuration. (c, d) Fundus autofluorescence exhibits hypoautofluorescent placoid lesions with irregular hyperautofluorescent borders in the posterior pole and midperiphery of both eyes. (e, f) Indocyanine green angiography displays hypofluorescent placoid choroidal lesions more widespread in the nasal periphery of the left eye than visible on fundus autofluorescence, signifying active inflammatory disease. Fluorescein angiography of the (g) right eye and (h) left eye early and (i) late demonstrates progressive staining and leakage from the placoid lesions.
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fig1
Fundus imaging (Figure 1) demonstrated hypoautofluorescent lesions in the macula and midperiphery of both eyes with irregular hyperautofluorescent borders.
Optical coherence tomography. Optical coherence tomography of the (a) right and (b) left eyes on initial visit. The macular lesions are associated with outer retinal irregularities in both eyes. After initiating treatment, the placoid lesions in the (c) right and (d) left eyes did not progress or improve 8 weeks after the initial visit.
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fig2
Optical coherence tomography demonstrated bilateral outer retinal disruption (Figure 2).