PMC4929375_01
A liver mass measuring 2.9 cm in segment 6/7 of the liver is shown on abdominal CT scan. The lesion was characterized as hypodense with peripheral rim enhancement and internal septation.
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F1
The lesion was better characterized on an abdominal CT scan with a diameter of 2.9 cm in segment 6/7 of the liver (fig. 1).
Biopsy of the liver lesion showed well-differentiated HCC. Magnification x200.
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F2
HCC. Histology revealed immunostaining positive for HepPar and CD10 with an absence of staining for CK7 and CK20 (fig. 2).
Non-neoplastic liver biopsy showed 30% macrovesicular steatosis and minimal iron overload (grade 0-1/4), but no steatohepatitis and no fibrosis. Magnification x200.
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F3
Biopsies from the non-neoplastic liver showed approximately 30% macrovesicular steatosis without any steatohepatitis or fibrosis, and minimal iron overload (grade 0-1/4; fig. 3).