PMC8289348_01
T2-weighted magnetic resonance images of thoracic vertebra in Case 1 at the time of the first (A and B) and last admissions (C and D). A, Sagittal view shows the thoracic spinal cord with a high-signal focus (arrow). B, Axial view shows the thoracic spinal cord and the "small print" sign (at the T5-T6 level; arrow). C, Sagittal and D, axial views show that the thoracic spinal cord lesions had partially recovered (at the T5-T6 level; arrows).
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Thoracic vertebral magnetic resonance image (MRI) showed long T2 signals in both dorsal and lateral columns at T5-T6, i.e., the "small character" sign (Figure 1A and B). Cervical and thoracic vertebral MRI showed similar changes in the cervical vertebrae as in the previous examinations, along with T10-11 intervertebral disc bulging, thoracic vertebral degeneration, and partial recovery of the T5-T6 spinal cord lesion (Figure 1C and D).
Gastroscopy images of chronic atrophic gastritis in Case 1. A, esophagus; B, gastric fundus; C, gastric body; D, gastric angular incisure; E, gastric antrum; F, duodenal bulb. The gastric mucosa at the atrophic site is red and white (arrows).
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Gastroscopy and biopsy showed type A chronic atrophic gastritis (Figures 2 and 3).
Pathological examination of a gastric antrum specimen in Case 1. A, Overall view (x40, scale bar 100 mum). B, Local view (x100, scale bar 50 mum) showing a small amount of normal antral glands (black arrows). C, Local view (x100, scale bar 50 mum) showing that the normal glands in the submucosal basal layer are completely atrophied (white arrows) and replaced with numerous intestinal goblet cells and metaplastic glands (black arrows).
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Gastroscopy and biopsy showed type A chronic atrophic gastritis (Figures 2 and 3).
PMC8289348_02
T2-weighted magnetic resonance images of thoracic vertebra in Case 2. A, Sagittal view shows high-signal intensity lesions in the thoracic spinal cord (arrows). B and C, Axial views show the spinal cord "small print" sign at different positions in the thoracic segment (B, T5 level; C, T10-T12 level; arrows).
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Thoracic vertebral MRI showed long T1 and T2 signals in both dorsal and lateral columns of T5-T6, i.e., the "small character" sign (Figure 4).