PMC7264952_01
A) The histological section shows a malignant neoplasm of epithelial origin consisting of cells arranged in islands invading the adjacent connective tissue. The stroma of dense connective tissue is permeated by an intense predominantly chronic inflammatory infiltrate (hematoxylin-eosin, 400x); B) The histological section shows malignant cells with cellular/nuclear pleomorphism and hyperchromatism, alteration of the nucleus/cytoplasm ratio, and atypical mitoses (hematoxylin-eosin, 1000x); C) Computed tomography showing extensive facial lesion, communicating with the oral cavity.
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The patient was referred to biopsy under general anesthesia and the histopathological report was "squamous cell carcinoma, grade III of the World Health Organization", with an unfavorable prognosis [Fig. 1].
Extensive facial lesion with presence of multiple larvae.
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He verbalized with difficulty, had edema, erythema, and extensive lesion comprising the middle and lower third region of the right side of the face, with necrotic and elevated edges, loss of skin substance, communication with the oral cavity, and approximately 150 larvae in extraoral region [Fig. 2].
Clinical appearance after complete larvae removal.
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After complete removal [Fig. 3], the patient started palliative chemotherapy and he was referred to radiotherapy [Fig. 4] and follow-up with a social worker and a psychology team.
In palliative care, two weeks before death.
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After four months, the patient died [Fig. 5].