PMC5311428_01
Lichen planus. Histopathology hematoxylin-eosin stain of biopsied lesion shows mixed infiltrate at the dermoepidermal junction and obliteration of the rete ridges, consistent with LP.
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fig1
Skin biopsy sections were taken, and histology found interface dermatitis with saw tooth ridging and dyskeratotic keratinocytes (Fig 1).
Lichen planus. Photographs taken 6 months before initiation of therapy (left) and 1 month after initiation of ledipasvir-sofosbuvir (right) show marked visible improvement of cutaneous lesions.
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One month after the initiation of therapy, the patient had a marked decrease in pruritus, with partial regression of his lesions compared with photographs taken 7 months prior (Fig 2).