PMC3246717_01
Upper endoscopic examination revealed a localized ulcerative lesion (diameter, 4 cm) located on the lesser curvature of the upper stomach.
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Upper endoscopic examination revealed a localized ulcerative lesion (diameter, 4 cm) located on the lesser curvature of the upper stomach (Figure 1).
Histological findings of the tumor (x 400). The tumor was uniform in shape and arranged in small microtubular structures (rosette-like arrangement) to form solid nests, with medium-sized, round-to-cuboid-shaped tumor cells. The tumor cells exhibited intense mitosis greater than 2/HPF (hematoxylin and eosin, (a)). Immunohistochemical staining showed that it was positive for synaptophysin (b) and chromogranin A (c). The Ki-67 labeling index was 70-80% (d).
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The tumor cells exhibited hyperchromatic nuclei and intense mitosis 46/10 HPF (Figure 2(a)). By immunohistochemical staining, the tumor cells were positive for synaptophysin (Figure 2(b)), chromogranin A (Figure 2(c)), and CEA and negative for S-100 protein. The Ki-67 labeling index was 70-80% (Figure 2(d)).