PMC5482168_01
MRI brain post-contrast showing a heterogeneously enhancing space occupying lesion in the lateral ventricles with extension into the foramen of Monro with obstructive hydrocephalus
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F1
T1-weighted postcontrast images, a heterogeneously enhancing mass lesion identified within the lateral ventricles in the proximity of the foramina of Monro [Figure 1].
MRI Brain T1 Weighted coronal images suggestive of a hyperintense lesion occupying the lateral ventricles and extending into the third ventricle. Hydrocephalus also evident
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F2
Major vessels showed normal flow voids and basal cisterns were preserved [Figure 2].
Alternating loose and compact areas characteristic of Pilocytic astrocytoma (x20)
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F3
Histopathology showed multiple fragments of a neoplastic lesion comprising spindle-to-stellate-shaped cells arranged in alternating compact and loose areas [Figure 3].
Abundant Rosenthal fibers in Pilocytic astrocytoma (x40)
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F4
There were associated thick walled, hyalinized blood vessels in the stroma along with areas exhibiting Rosenthal fibers and hyaline globules [Figure 4].
GFAP shows diffuse staining in pilocytic astrocytoma
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F5
Immunohistochemically, the tumor cells were diffusely positive for glial fibrillary acidic protein (GFAP) [Figure 5].