PMC3808232_01
Peripheral Blood film showing sickle cells at 100x.
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PG, WBC: 5.8x109/L, and platelets: 114x109/L. Peripheral film review showed presence of numerous sickle cells, polychromasia, nucleated red blood cells, and target cells (Figure 1).
Bone marrow aspirate at 40x showing erythroid hyperplasia.
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There was presence of erythroid hyperplasia with dyserythropoietic changes and many sickle cells in the background (Figure 2).
Area of central necrosis surrounded by fibroblasts at 40x.
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Bone trephine, however, revealed increased cellularity, mainly consisting of erythroid hyperplasia along with patch of haemopoietic tissue showing multiple areas of central necrosis surrounded by fibroblasts (Figures 3 and 4).
Bone trephine section showing necrosis at 20x.
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Bone trephine, however, revealed increased cellularity, mainly consisting of erythroid hyperplasia along with patch of haemopoietic tissue showing multiple areas of central necrosis surrounded by fibroblasts (Figures 3 and 4).