PMC4246614_01
(A) Contrast-enhanced axial computed tomography image of a 48-year-old female patient with ileocecal intussusception. An ~3.5-cm oval-shaped mass can be observed as a lead point (arrow), and mesenteric fat and vessels, as well as bowel wall thickening of the intussusceptum and intussuscipiens (arrowhead) are also apparent. (B) The intraluminal polypoid mass extended into the subserosa (arrows). (C) The epithelioid tumor cells are embedded in an edematous, fibromyxoid stroma with prominent vasculature. The absence of concentric tumor cell proliferation should be noted. (stain, hematoxylin and eosin; magnification, x200). (D) The tumor was centered in the submucosa and extended into the mucosa (magnification, x100). (E) The spindle to epithelioid tumor cells were haphazardly arranged in the edematous subserosa. The heavy inflammatory infiltrate with eosinophils should be noted. (stain, hematoxylin and eosin; magnification, x400). (F) Despite low tumor cellularity, the tumor cells showed mitotic figures (arrows) (stain, hematoxylin and eosin; magnification, x400). (G) The tumor cells were positive for cluster of differentiation 34 (magnification, x400). (H) Smooth muscle actin staining showed a disrupted muscularis propria by infiltrating tumor cells (arrow) (magnification, x100).
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The patient underwent contrast-enhanced abdominal computed tomography, which revealed an ileocecal-type intussusception in the right lower quadrant of the abdomen (Fig. 1A). The cut surface was myxoid and showed multiple hemorrhagic foci (Fig. 1B).