PMC6552342_01
Imaging findings. (a) Ultrasonography showed a circumscribed hypoechoic mass. (b) Magnetic resonance imaging (MRI) before enhancement did not show details of the tumor. (c) Enhanced MRI showing a mass with enhancing internal septation, early peak.
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Ultrasonography showed a circumscribed hypoechoic mass measuring 23 x 19 x 17 mm3 that was oval in shape, with a parallel orientation and posterior acoustic enhancement (Figure 1(a)). Enhanced breast magnetic resonance imaging (MRI) revealed an oval mass with enhancing internal septation, an early peak, and a delayed washout pattern (Figure 1(b) and (c)).
Breast reconstruction. (a) Creating a latissimus dorsi flap after partial mastectomy. (b) State at the time of the end of surgery.
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We performed partial mastectomy, sentinel lymph node biopsy, and latissimus dorsi muscle flap transfer (Figure 2(a) and (b)).
Pathological findings (magnification x 100). (a) The specimen shows proliferation of both epithelial and mesenchymal components (hematoxylin and eosin staining). The tumor is positive for (b) AE1/3 staining and (c) MNF-116 staining.
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The mesenchymal element contained sheets of spindle-shaped cells (Figure 3(a)). Immunohistochemically, the epithelial element was positive for cytokeratins (AE1/3 and MNF-116) (Figure 3(b) and (c)) but negative for myoepithelial markers (smooth muscle actin (SMA) and calponin).
Pathological findings (magnification x 100). The tumor is positive for (a) smooth music actin, (b) h-caldesmon, (c) calponin, and (d) HHF-35 staining and negative for (e) s-100 and (f) desmin staining.
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The mesenchymal element was positive for SMA, h-caldesmon, calponin, and HHF-35 and negative for AE1/3, MNF-116, S-100, and desmin (Figure 4(a)-(f)).