PMC9969434_01
Microscopic section of the vertebral bone lesion (haematoxylin and eosin).
The lesion consists of proliferations of well differentiated blood vessels.
Circles indicate capillaries; stars indicate arterioles and venules; and
triangles indicate small trabeculae of lamellar bone
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Figure 1 shows a microscopic section of the vertebral bone lesion described.
Transverse and sagittal CT view at the T5 vertebral lesion, highlighting the
radiation therapy contour planning. The red circles denote the planning
target volume; the pink circles denote the gross tumour volume; and the
orange circles denote the clinical target volume
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Figure 2 presents the gross tumour volume (GTV), the clinical target volume (CTV) and planning target volume (PTV) for the radiation course.
Comparative MRI images. Top images were obtained at the time of diagnosis
(preoperatively and before radiation therapy). Bottom images were obtained
at 6 months post-radiation therapy. (a) Transverse T2-weighted (T2W) at the
level of T5 showing a moderate left-sided compression of the spinal cord by
an heterogeneous extradural mass originating from the T5 vertebra. (b)
Transverse T1-weighted (T1W) fat saturation (FAT SAT) image postcontrast at
the level of T5, showing homogeneous contrast enhancement of the extradural
mass. (c) Transverse T2W at the level of T5 showing a mild left-sided
compression of the spinal cord by a heterogeneous extradural mass
originating from the T5 vertebra and (d) Transverse T1W FAT SAT postcontrast
image at the level of T5 showing no abnormal contrast enhancement of the
extradural mass. The white arrow points at the extradural mass effect
resulting from the thickened left vertebral pedicle of T5. Dr = dorsal;
L = left
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Figures 3 and 4 compare the preoperative CT and MRI, and after radiation therapy.
Transverse CT images and bone window at the level of the mid part of the T5
vertebra (top images) and the caudal part of the T5 vertebra (bottom images)
at different time points after radiation therapy. (a,f) At the time of
diagnosis, prior to surgery, (b,g) 2 months postoperatively at the time of
clinical relapse, (c,h) 3 months post-radiation therapy, (d,i) 6 months
post-radiation therapy and (e,j) 19 months post-radiation therapy
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Figures 3 and 4 compare the preoperative CT and MRI, and after radiation therapy.