PMC7080855_01
(A) Transverse plane post-contrast, white arrows show the contrast enhancement of the nasal mucosal tissue. There is also soft tissue abutting the osseous scrolls of the caudal nasal passage. The choanae are obscured by soft tissue (#) (B) Transverse plane post-contrast, there is dependent soft tissue within the right frontal sinus (*). There is also a white arrow showing enhancement of the mucosal tissue in the sphenoidal sinus and non-contrast enhancing tissue in the nasopharynx (#). (C) Transverse plane post-contrast, white chevrons show enhancing optic nerve bilaterally. (D) Dorsal oblique plane post-contrast, white chevrons highlight the optic discs.
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F1
There was diffuse contrast enhancement of the soft tissue that lined the osseous scrolls (Figure 1A). The nasal soft tissue extended from the nares caudally to the ethmoid turbinates and into the frontal sinuses and sphenoidal sinus (Figure 1B). The soft tissue within the frontal sinuses collected in the dependent portion with fluid wicking along the margins (Figures 1B,C). The choanae were filled with soft tissue obstructing the patency of the nasopharyngeal upper airway (Figures 1A-C). There was focal enhancement within the posterior ocular globes within the region of the optic disc and the optic nerve heterogeneously contrast enhanced (Figures 1C,D).
(A) Nasal biopsy impression smears revealed numerous markedly degenerate neutrophils with intracellular bacteria of variable, but predominantly rod-shaped, morphology (Wright-Giemsa, 100x). (B) Neutrophils extravasating from reactive and congested blood vessels and multifocally clustered within the respiratory mucosa. (Hematoxylin and Eosin stain). (C) Rounded, desquamated epithelium in a pool of suppurative exudate and hemorrhage that contains gram negative bacteria (Hematoxylin and Eosin stain).
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F2
Cytology results described the nasal samples as containing numerous degenerative neutrophils frequently containing intracellular bacterial rods of varying morphology with rare bacterial cocci noted (Figure 2A). Animal Health, Shawnee Mission, KS, USA; 7.4 mg/kg, PO, q 24 h), and nebulization with 3 mls of 0.9% saline (q 12 h). Histopathologic sections revealed dense sheets of an almost pure population of neutrophils in which there were a myriad of bacterial colonies that appeared to have a short rod and thin filamentous morphology (Figures 2B,C). Aerobic/anaerobic bacterial culture results returned on day 6 and indicated the presence of E. coli and Actinomyces spp. (Supplemental