PMC9732113_01
A, Violaceous, scaly, flat-topped papules on the ventral wrists; (B) blisters on feet.
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A) and trunk with numerous tense bullae on the lateral feet and toes (Fig 1, B). A punch biopsy was performed on the right ventral distal forearm that showed a dense lichenoid lymphocytic infiltrate with necrotic basal keratinocytes that was consistent with lichen planus.
New papulovesicular eruption on the face.
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Six months later, the patient presented with a recurrence of his LPP that now included papulovesicles on the face and neck as well as his typical lichenoid lesions on the distal extremities (Fig 2).
A, Face completely clear after 15 weeks of dupilumab; (B) feet completely clear after 15 weeks of dupilumab.
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After 15 weeks on dupilumab, patient was completely clear (Fig 3, A and B).