PMC7498628_01
PMC7498628_02
Echocardiogram at 6 days of life, showing significant biventricular hypertrophy.
fimmu-11-01929-g0001.jpg
PMC7498628_02_fimmu-11-01929-g0001.jpg
F1
Echocardiogram performed on day 6 of life revealed biventricular hypertrophy with prominent moderator band and muscle bundles (Figure 1).
Echocardiogram at 11-weeks of life, showing resolution of ventricular hypertrophy.
fimmu-11-01929-g0002.jpg
PMC7498628_02_fimmu-11-01929-g0002.jpg
F2
Complete recovery of cardiac function and left ventricular mass was seen by 11 weeks of age (Figure 2). Complete recovery of cardiac function and left ventricular mass was seen by 11 weeks of age (Figure 2).
Anti-rhGAA IgG antibody titers, CK, AST, and ALT over time. ERT, enzyme replacement therapy; mg, milligram; kg, kilogram; CK, creatine kinase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; U, units; L, liter.
fimmu-11-01929-g0003.jpg
PMC7498628_02_fimmu-11-01929-g0003.jpg
F3
Hex4 at 50 months of age. Her AST, ALT, and total CKs have also been in the normal range (Figure 3).