PMC9068340_01
Characteristic crazy paving pattern in a patient referred to lung transplantation because of Niemann-Pick type B disease.
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He had extensive pulmonary involvement at chest computed tomography (CT) with a diffuse interstitial disease and a radiological pattern of "crazy paving" in the lower and middle lung fields (Figure 1).
Macroscopic view of the explanted lungs.
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Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).
Microscopic section of lung parenchyma. Morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of Niemann-Pick disease.
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Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).
At higher magnification, foamy histiocytes.
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Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).