PMC6000998_01
Mediolateral-Oblique (MLO) and Cranial-Caudal (CC) views of the left breast, show a well-defined, fat-containing mass, suggesting a hamartoma. The mass has a relatively high density compared to surrounding breast tissue.
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Mammography showed a well-defined mass, which included fat densities, in an elliptical mass in the same location found on physical examination (Fig. 1).
Ultrasonography, showing a well-defined mass 36 x 24 mm in size containing both hypoechoic and hyperechoic lesions.
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Ultrasound examination showed a well-defined mass which was 36 x 24 mm in size and with mixed by hypoechoic and hyperechoic areas (Fig. 2).
Two core biopsies were performed showing similar results. Hematoxylin and eosin stained sections (a, x100.) show an increase in glandular elements plus stromal proliferation and indistinct myoepithelial cells, which looked like invasive ductal carcinoma, but immunohistochemistry (b, x100.) show a normal two layer structure of mammary glandular epithelial cells and myoepithelial cells, diagnosed as sclerosing adenosis.
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Histopathology showed an increase in glandular elements with stromal proliferation and indistinct myoepithelial cells, which looked like invasive ductal carcinoma, but immunohistochemistry showed a normal two-layer structure of mammary glandular epithelial cells and myoepithelial cells which led to the diagnosis of sclerosing adenosis (Fig. 3).
Specimens from a partial mastectomy. The tumor was elastic and did not appear to infiltrate surrounding tissue. Ductal carcinoma in situ (the black line) in an area of sclerosing adenosis (the red line), in a hamartoma (the dotted line).
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The postoperative pathological diagnosis was DCIS in an area of sclerosing adenosis, in a hamartoma (Fig. 4, Fig. 5).