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Figure 3a. Patient 1 HRCT Before Tacrolimus Treatment. 12/2008: HRCT during patient 1's initial hospitalization demonstrates reticulonodular interstitial abnormalities and patchy ground-glass opacities bilaterally.. Figure 3b. Patient 1 HRCT After Tacrolimus Treatment. 10/2009: HRCT 6 months post-tacrolimus initiation reveals that the reticular interstitial opacities are less coarse and ground-glass opacities are decreased.
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Surgical lung biopsy revealed OP. (figure 3a). The addition of tacrolimus resulted in improvement in respiratory symptoms, oxygenation, serologies, lung function and HRCT (table 4, figure 3b).
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