PMC6145538_01
Abdominal CT scan revealing a 7 cm hypervascular mass (arrow) involving the splenic vein. Typically, RCC metastases are hypervascular with contrast enhancement, multicentric, and without peripancreatic lymphadenopathy. CT, computed tomography; RCC, renal cell carcinoma.
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A 70-year-old man presented in 2017 after discovery of a hypervascular, expansile, 7 cm pancreatic body mass involving the splenic vein on routine surveillance CT scan (Fig. 1).
(A) Gross specimen including the pancreatic mass (left) and spleen (right). (B) Histology of pancreatic mass (H&E, 20x ). At lower power, the tumor cells are arranged in alveolar and solid growth pattern, with rich network of small thin-walled blood vessels. (C) Histology of pancreatic mass (H&E, 200x ). At higher power, the lesional cells have clear cytoplasm with distinct cell borders, with large and round nuclei. H&E, hematoxylin and eosin.
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Grossly, a 6.5 x 6.2 x 4.5 cm well-circumscribed mass is located within the pancreatic parenchyma (Fig. 2A). Histologically, the tumor has alveolar and solid growth pattern, with rich network of small thin-walled blood vessels (Fig. 2B). At higher power, the lesional cells have clear cytoplasm with distinct cell borders, with large and round nuclei (Fig. 2C).