PMC5207330_01
Endoscopic image of gastric mucosa with granular mucosa with adenomatous pattern.
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In the antrum, prepyloric fold did not modify with blowing, and biopsies were taken from all suspected areas (Figure 1).
Hematoxylin and eosin staining of the gastric specimen demonstrating strands of invasive cells in the mucosa.. Notes: (A) Lobular breast cancer cells individually dispersed in a single-cell-file pattern around gastric glands (10x magnification). (B) Discohesive lobular breast cancer cell pattern in gastric specimen (10x magnification). (C) Gastric mucosa infiltrated by lobular breast cancer cells adopting the typical "Indian file" pattern (10x magnification). (D) Immunohistochemical staining for cytokeratin CK19 demonstrating breast cancer cells in gastric mucosa (20x magnification).
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Mucous gastric metastases were positive for cytokeratin-19 and hormonal receptors (Figure 2).
Endoscopic image of colonic mucosa.. Notes: (A) Colonic mucosa erosion (arrow). (B) Several polyps in colonic mucosa (arrows).
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A colonoscopy was performed in February 2009, which showed a polyp that was subsequently excised, and a pathology report showed metastases from a lobular breast cancer, also positive for cytokeratin-7 and hormonal receptors (Figures 3 and 4).
Biopsy of colonic mucosa.. Notes: (A) Hematoxylin and eosin staining demonstrating strands of invasive cells in the mucosa (10x magnification). (B) Immunohistochemical staining for cytokeratin CK7 demonstrating breast cancer cells in colonic mucosa (20x magnification). (C) Immunohistochemical staining for estrogen receptors demonstrating breast cancer cells in colonic mucosa (20x magnification).
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A colonoscopy was performed in February 2009, which showed a polyp that was subsequently excised, and a pathology report showed metastases from a lobular breast cancer, also positive for cytokeratin-7 and hormonal receptors (Figures 3 and 4).