PMC9852497_01
MRI manifestations of hepatic sarcomatoid carcinoma. The magnetic resonance imaging (plain scan + enhanced + functional imaging) shows abnormal signals of irregular mass in the liver, with a size of approximately 9.5 x 8.3 cm. The T1WI (A) shows a weak signal; however, the T2WI (B) and the DWI (C) show strong signals. The arterial phase (D) indicates slightly uneven enhancement at the edge of the lesion, with continuous uneven enhancement in the portal phase (E) and delayed phase (F).
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F1
Irregular masses of long T1 (Figure 1A) and long T2 (Figure 1B) abnormal signals in the space between the liver and the stomach were detected through magnetic resonance imaging (MRI) of the tumor (plain scan + enhanced + functional imaging). Diffusion-weighted imaging (DWI) (Figure 1C) shows a strong signal, and the enhancement (Figures 1D-F) indicates progressive heterogeneous enhancement.
Pathology and immunohistochemistry of hepatic sarcomatoid carcinoma and gastrointestinal stromal tumors. Hematoxylin and eosin (H & E) staining of hepatic sarcomatoid carcinoma (A); the results of immunohistochemical staining of hepatic sarcomatoid carcinoma show CK positive x200 (B) and AE1/AE3(+) positive x200 (C); H&E staining of gastrointestinal stromal tumor (D); the results of immunohistochemical staining of the gastrointestinal stromal tumor shows CD117 positive x200 (E) and DOG-1 positive x200 (F).
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F2
The immunological markers were as follows: CK (+) (Figure 2B), Vim (-), CD117 (-), Dog-1 (-), CD34 (-), SMA (-), Ki-67 (+, ~60%), GPC-3 (-), and Hepar-1 (-). The relevant immunohistochemical markers were as follows: Vim (+), CD117 (+) (Figure 2E), CD34 (+), Dog-1 (+) (Figure 2F), Ki-67 (+, ~5%), SMA (-), S-100 (-).
Related imaging data and clinical specimens of gastric recurrence of hepatic sarcomatoid carcinoma. A regular CT scan of the abdomen showed the presence of an irregularly shaped and uneven-density occupancy in the area between the greater curvature of the stomach and the omental sac (A), the size was approximately 53 x 78 x 100 mm; the specimen is off-white (B) and shows internal necrosis (C).
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F3
Imaging examinations revealed the presence of an irregular and substantial mass in the area between the greater curvature of the stomach and the omental sac (Figure 3A), and the enhanced CT scan showed uneven enhancement. The tumor was 53 x 78 x 100 mm in size, gray in color, and showed internal necrosis (Figures 3B,C).