PMC3362184_01
Melanocytic nevi with epidermal scaling and an erythematous perinevic halo.
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PMC3362184_01_cde-0004-0092-g01.jpg
F1
Yet, the last physical examination evidenced the presence of epidermal scaling and an erythematous perinevic halo on 3 long-standing melanocytic lesions on his trunk; the clinical appearance of the lesions was highly suggestive of Meyerson nevi (fig. 1).
a-c A dense infiltrate at the dermoepidermal junction composed by lymphocytes with hyperchromatic nuclei, exocytosis, and focal epidermotropism, together with junctional melanocytic nests. d Immunohistochemistry showing S-100 protein-positive staining in melanocytic nevus cells.
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PMC3362184_01_cde-0004-0092-g02.jpg
F2
The nevus was mostly composed of melanocytic nests at the dermoepidermal junction, associated with particularly abundant band-like lymphocytic infiltrates obscuring the dermoepidermal junction, and characterized by focal epidermotropism of hyperchromatic, enlarged, convoluted lymphocytes (fig. 2a-c). T cells (fig. 2e, f), with low CD7 expression. These findings were consistent with the diagnosis of MF superimposed on a junctional melanocytic nevus.