PMC6280806_01
a Optical coherence tomography images of patient 1 obtained just before C3F8 intravitreal injection. The figure shows a vitreomacular traction with schisis-like splitting of the retina. The posterior vitreous is still attached at the optic disc. b Ten weeks after injection the vitreomacular traction was released, but a lamellar hole with intraretinal cysts developed
717_2017_382_Fig1_HTML.jpg
PMC6280806_01_717_2017_382_Fig1_HTML.jpg
Fig1
SD-OCT-confirmed VMT in the right eye in March 2013 (Fig. 1a). Secondary ophthalmological findings were diabetic maculopathy, proliferative diabetic retinopathy, as well as a macula pucker. The foveal thickness was 571 mum after treatment and BCVA after resolution of traction was 0.1 (Fig. 1b).
PMC6280806_02
a Baseline spectral domain optical coherence tomography (OCT) of patient 2 with vitreomacular traction. OCT showed that the maximal diameter of the adhesion in horizontal scans was 803 mum. The retinal anatomy was disrupted under the adhesion zone. b Three weeks after the injection, no release of VMT was seen and the retinal thickness increased by 236 microm
717_2017_382_Fig2_HTML.jpg
PMC6280806_02_717_2017_382_Fig2_HTML.jpg
Fig2
August 2013 with a VMT in the left eye diagnosed with SD-OCT (Fig. 2a). While BCVA increased to 0.4, no release of traction was seen and the foveal thickness increased to 816 mum (Fig. 2b).
PMC6280806_03
a Preoperative optical coherence tomography of patient 3 with vitreomacular traction (VMT) and a huge cyst in the inner retinal layer. The ellipsoid zone underneath the VMT was disrupted. b VMT release and restoration of the ellipsoid zone 12 days postoperatively
717_2017_382_Fig3_HTML.jpg
PMC6280806_03_717_2017_382_Fig3_HTML.jpg
Fig3
Focal VMT was diagnosed on OCT with an adhesion diameter of 217 mum, a foveal thickness of 446 mum, and a BCVA of 0.63 (Fig. 3a). The vitreous released successfully 12 days after the injection with a postoperative foveal thickness of 200 mum and an improvement of BCVA to 0.8 (Fig. 3b).
PMC6280806_04
a Baseline spectral domain optical coherence tomography of patient 4 with a macular hole and vitreomacular traction (VMT). b One week after injection of gas, the VMT released but the macular hole did not close. Therefore, 5 weeks later the patient underwent vitrectomy with gas
717_2017_382_Fig4_HTML.jpg
PMC6280806_04_717_2017_382_Fig4_HTML.jpg
Fig4
The fourth patient, a 72-year-old man, saw a blind spot in the central vision in his left eye in October 2013, which was diagnosed on SD-OCT as a small MH (201 mum) with an adhesion expanse of 218 mum (Fig. 4a). After another 1 week, there were no more signs of tractional forces seen on OCT; however, the hole remained open and increased to 475 mum (Fig. 4b).
PMC6280806_05
a Baseline optical coherence tomography (OCT) of the left eye of patient 5 with vitreomacular traction (VMT) and with a huge cyst in the inner retinal layer and disruption of the ellipsoid zone. b About 5 months postoperatively, OCT of the left eye shows VMT release and restoration of the ellipsoid zone
717_2017_382_Fig5_HTML.jpg
PMC6280806_05_717_2017_382_Fig5_HTML.jpg
Fig5
SD-OCT a VMT with an adhesion diameter of 397 mum and a macular cyst were diagnosed in the left eye with the right eye not showing any pathology (Fig. 5a). She had an initial BCVA of 1.0 and the foveal thickness was 335 mum. There was no macula cyst detectable on SD-OCT after resolution (Fig. 5b). 
a About 1 year after the initial procedure, patient 5 presented with similar findings on optical coherence tomography (OCT) of the right eye. b Three weeks after intravitreal injection, OCT of the right eye shows vitreomacular traction release and restoration of the ellipsoid zone
717_2017_382_Fig6_HTML.jpg
PMC6280806_05_717_2017_382_Fig6_HTML.jpg
Fig6
In December 2014, when patient 5 was now aged 51, VMT with an adhesion diameter of 397 mum was diagnosed with SD-OCT in her right eye (Fig. 6a). Three weeks later the vitreous body detached from the retina (Fig. 6b).
PMC6280806_06
a Optical coherence tomography (OCT) of patient 6 obtained just before C3F8 intravitreal injection shows a tent-like elevation of the retina with intraretinal cystoid spaces due to vitreomacular traction force. b Five weeks after injection, there is resolution of vitreomacular traction with some residual intraretinal cysts on OCT
717_2017_382_Fig7_HTML.jpg
PMC6280806_06_717_2017_382_Fig7_HTML.jpg
Fig7
Patient 6 was a 75-year-old woman who was diagnosed with VMT in her right eye with OCT in September 2015 (Fig. 7a). After 5 weeks, a separation of the vitreous from the macula could be seen on OCT (Fig. 7b).