PMC5344216_01
Light Microscopy Jones' Silver Stain 40x.. There is mild increase in mesangial matrix and cellularity. The glomerular basement membranes are unremarkable without spikes, holes, splitting, or corrugation.
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A percutaneous kidney biopsy was subsequently performed revealing IgM dominant mesangioproliferative GN with features suggestive of CG (Fig. 1, Fig. 2, Fig. 3, Fig. 4), likely related to chronic infection including chronic hepatitis C or chronic bacterial infection.
Kappa and Lambda Immunofluorescence.. On a scale of 0-3+, there is equal 1-2+ diffuse segmental to global granular mesangial staining for kappa and lambda.
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A percutaneous kidney biopsy was subsequently performed revealing IgM dominant mesangioproliferative GN with features suggestive of CG (Fig. 1, Fig. 2, Fig. 3, Fig. 4), likely related to chronic infection including chronic hepatitis C or chronic bacterial infection.
Transthoracic Echocardiogram. Vegetations seen on the aortic valve (A) and mitral .. Valve (B).
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Subsequent transesophagealechocardiogram confirmed these results and revealed mitral and aortic valve vegetations (Fig. 5, Fig. 6, Fig. 7 ).
Transthoracic Echocardiogram.. Color flow doppler image showing severe aortic insufficiency.
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Subsequent transesophagealechocardiogram confirmed these results and revealed mitral and aortic valve vegetations (Fig. 5, Fig. 6, Fig. 7 ).