PMC2823598_01
PMC2823598_02
PMC2823598_03
Case No. 3 (A) Pretreatment stroboscopy revealed tumor involvement in the right AE fold, extending down into the right piriform sinus (B) Post-radiation - Only a small remnant of tumor remained after radiation and continued to be stable throughout follow-up.
1758-3284-2-2-1.jpg
PMC2823598_03_1758-3284-2-2-1.jpg
F1
On flexible laryngoscopy, the patient had a right laryngeal mass emanating from the right false cord and extended to the aryepiglottic fold and epiglottis (Figure 1).
PMC2823598_04
Case No. 4 (A) A large laryngeal paraganglioma is noted in the left arytenoid area. (B) There is involvement of the laryngeal and lingual surfaces of the epiglottis.
1758-3284-2-2-2.jpg
PMC2823598_04_1758-3284-2-2-2.jpg
F2
On laryngoscopy, the lesion extended from the posterior aspect of the left arytenoid to along the aryepiglottic fold and false vocal cord onto the epiglottis (Figure 2).
Case No. 4 - (A) Epiglottic extension (B) Tumor pushing the airway to the right (C) Near-total laryngeal obstruction (D) Extension of tumor is found in the left anterior subglottis.
1758-3284-2-2-3.jpg
PMC2823598_04_1758-3284-2-2-3.jpg
F3
The left subglottic component of the tumor probably extended for about 3-5 mm below the level of the true vocal cord (Figure 3).
Case No. 4 (A) Overlying squamous epithelium with the tumor in the submucosa. The circular focus is a post-embolized vessel. (B) Higher power 400x - Zellballen nests of tumor cells with thin supporting sustenacular cells around each nest.
1758-3284-2-2-4.jpg
PMC2823598_04_1758-3284-2-2-4.jpg
F4
This immunohistochemical profile substantiated the diagnosis of paraganglioma (Figure 4).