PMC10358287_01
Clinical images. The non-segmental/bilateral depigmented macules over the hands (A), fossa axillaries (B), and feet (C). Vitiligo-like lesions over the lower back (D). Multiple irregularly, well-demarcated, hypopigmented lesions surrounded by normal skin.
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F1
A dermatological examination revealed multiple depigmented macules of varying sizes over the hands, forearms, thighs, feet, fossa axillaries, and lower back (Figure 1).
Biopsy with H&E staining of depigmented macule, x20 magnification (A) and x40 magnification (B). Melanocytes and melanin granules in the epidermis of the leukoplakia area were absent.
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F2
Skin biopsies were taken from depigmented macules; the histological pathology shows the complete absence of melanocytes and melanin, in addition to a mild infiltration of inflammatory cells around the blood vessels (Figure 2).