PMC6615080_01
Right foot medial fifth digit with granulomatous mass
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Fig1
Upon initial wound center presentation, a granulomatous mass was noted to the medial aspect of the right fifth digit (Fig. 1).
Right foot fifth digit partial thickness wound with sloughed granulomatous mass
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Fig2
However, upon presenting to the biopsy procedure, the patient stated the granulomatous mass had sloughed off in his sock the week prior leaving only a small partial-thickness ulcer (Fig. 2).
Right foot fifth digit with two distinct cyanotic papules
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Fig3
The distal papule measured 0.5 cm in diameter and the proximal papule measured 0.7 cm in diameter (Fig. 3).
Histopathology hematoxylin and eosin stain with magnification 200X showing spindle cell proliferation and slit-like vascular spaces
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Fig4
Hematoxylin and eosin stain demonstrated dermal nodules with haphazard spindle cell proliferation of endothelial cells forming vascular spaces which is diagnostic of classic KS (Fig. 4).
Proliferated spindle cells demonstrate positive staining (brown) of the antibody to HHV-8
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Fig5
The tumor cells showed diagnostic positive staining for HHV-8 (Fig. 5).