PMC8559630_01
Computed tomography image showing an 8.8 x1.6.8 x1 cm mass in the head of pancreas
cjim-12-407-g001.jpg
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F1
Abdominal and pelvic computed tomography (CT) has been considered for confirming the diagnosis and heterogeneous enhancing mass lesion measured 8.8x1.6.8.x1 cm in the pancreas's head (figure 1) was reported accordingly.
PMC8559630_02
PMC8559630_03
Markedly pleomorphic tumor cells in diffuse sheets showed clouds of squamous cells with keratin pearls displaying in the hemorrhagic necrotic tissue (hematoxylin and eosin staining, magnification, x200)
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F2
Highly mitotic activity with atypical mitosis and granular eosinophilic cytoplasm was also observed (figure 2).
Histological finding showed a positive result for immunohistochemistry staining A, P63 marker B, CK5/6 marker (magnification, x400)
cjim-12-407-g003.jpg
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F3
In addition, immunohistochemical (IHC) staining revealed that the samples were positive for CK5/6 and P63 markers, sensitive markers for squamous differentiation, which had confirmed our diagnosis (Figure 3).
PMC8559630_04
PMC8559630_05