PMC6971094_01
Ultrasound image of the uterus, indicating the increased size and tighter uterine wall of irregular contour.
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F1
Also, homogeneous intramural cystic structures and a hypoechoic luminal fluid associated with cystic walls were found (Figure 1).
(A) Polycystic left ovary with evidently increased size (3.0 x 2.5 cm) (White arrow). (B) Right ovary exhibiting hair, cartilage (Red arrows), and bone tissue (asterisk).
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F2
The ovaries were found polycystic, measuring 3.0 x 2.5 cm, with normal color and aspect (Figure 2A). In a sagittal cutting of the right and left ovaries, hair, and bone tissue (Figure 2B), and polycystic structures were found, respectively.
Left ovary. Microscopic evidence of GCT. The Call-Exner bodies, pathognomonic of GCT (arrowheads), and abundant stromal tissue (asterisks) are observed. Several areas exhibit the typical Sertoli pattern H&E Staining, 400X. Scale bar: 200 mum.
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F3
The histopathological exam evidenced a GCT in the left ovary, GCT in a solid tubular pattern containing Call-Exner bodies, tubular structures typical of a Sertoli pattern, surrounded by abundant stromal tissue (Figure 3).
Right ovary. Mature and well-differentiated teratoma showing the following structures: (A) Cartilage (red arrow), glandular tissue (see eosinophilic content in the upper left corner), and adipose tissue (asterisks) (H&E staining, 400X). (B) Bone tissue (white arrow) (H&E staining, 200X). (C) Cystic hair follicle (red arrow) (H&E staining, 400X). (D) Cartilage (red arrow), and adipose tissue (asterisks) (H&E staining, 400X). Scale bars: 100 and 200 mum.
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F4
In the right ovary, a well-differentiated teratoma was found (Figures 4, 5) that included fragments of perichondrium-containing hyaline cartilage (Figure 4A), trabecular and compact bone (Figure 4B), smooth muscle, sweat glands, hair follicles, stratified cylindrical, and simple plane epithelium. Abundant cavities covered by a stratified keratinized flat epithelium, containing abundant keratin, and supported by a dense connective tissue and adipose tissue were found (Figures 4C,D).
Right ovary. Mature well-differentiated teratoma exhibiting a dentine-pulp complex: dentine filaments (asterisks), pre-dentine zone (red arrows), the odontoblast layer (white arrowheads), and the pulp zone (white arrow). (H&E staining, 1,000X). Scale bars: 50 mum.
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F5
In the right ovary, a well-differentiated teratoma was found (Figures 4, 5) that included fragments of perichondrium-containing hyaline cartilage (Figure 4A), trabecular and compact bone (Figure 4B), smooth muscle, sweat glands, hair follicles, stratified cylindrical, and simple plane epithelium. Finally, a dentin-pulp complex containing dentine, pre-dentine, odontoblasts, and pulp was found (Figure 5).