PMC5512415_01
Patient with verruciform xanthoma of tongue
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F1
On clinical examination, well-circumscribed, sessile, papillomatous, reddish growth was seen on tip of the tongue [Figures 1 and 2].
Minimal extension of lesion on ventral surface of the tongue
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F2
On clinical examination, well-circumscribed, sessile, papillomatous, reddish growth was seen on tip of the tongue [Figures 1 and 2].
Excision of the lesion
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F3
Hence, excisional biopsy was performed under general anesthesia [Figure 3].
Parakertinized stratified squamous epithelium with juxtaepithelial areas of xanthoma cells (H and E, x100)
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F4
On histopathological examination [Figures 4 and 5], the epithelium is parakeratotic stratified squamous with parakeratin plugging in between the clefts of projections.
Xanthoma cells along with vascular channels and inflammatory cells in papillary portion of lamina propria (H and E, x400)
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F5
On histopathological examination [Figures 4 and 5], the epithelium is parakeratotic stratified squamous with parakeratin plugging in between the clefts of projections.