PMC3268170_01
(A) Fundoscopy revealed vitreous haziness and opacity. (B) Slit lamp exam revealed a nodular, depigmented, mass-like appearance of the iris (black arrow) and a pinkish lump in the iris (white arrow).
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F1
Opthalmoplegia, vitreous opacity, and an iris mass developed in the left eye (Fig. 1A and 1B).
(A) This photograph demonstrates multiple erythematous and violaceous, well-defined, coin-sized plaques and nodules in the lower limbs. (B) The neoplastic infiltrate was composed of small- to medium-sized pleomorphic lymphocytes with irregular nuclei, inconspicuous nucleoli, and scant cytoplasm. (C) Immunotype was CD56+. (D) Immunotype was CD3+.
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F2
Skin manifestations of the lymphoma were noted 40 days post-chemotherapy (Fig. 2A). Skin biopsy confirmed neoplastic infiltration of small- to medium-sized pleomorphic lymphocytes with irregular nuclei, inconspicuous nucleoli, and scant cytoplasm (Fig. 2B). Immunohistochemical staining was positive for CD56 (Fig. 2C) and CD3 (Fig. 2D).
(A) Vitreous opacity resolved after radiotherapy at 900 cGy. (B) The iris masses resolved after radiotherapy at 900 cGy.
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F3
After receiving radiotherapy at 900 cGy, her visual acuity improved and her anterior uveitis, vitreous opacity, and iris mass resolved (Fig. 3A and 3B).