PMC9876725_01
Findings on light microscopy of renal biopsy specimens. Light microscopy findings revealed fibrin thrombi (yellow arrows) in the glomerular capillaries, endothelial swelling (blue arrows), mesangial proliferation (green arrows), and cellular crescent formation (red arrows) (A, D: periodic acid Schiff stain; B, E: periodic acid methenamine-silver stain; C, F: Masson's trichrome stain; original magnification, x200).
1349-7235-62-0091-g001.jpg
PMC9876725_01_1349-7235-62-0091-g001.jpg
g001
A renal biopsy revealed fibrin thrombi in the glomerular capillaries, endothelial swelling, mesangial proliferation, and cellular crescent formation (Fig. 1).
Findings of immunofluorescence staining of renal biopsy specimens. Immunofluorescence staining showed deposits of IgM, C3, and C4 in the glomerular vessels and mesangial area and no deposition of IgG, IgA, or C1q (A: IgG; B: IgA; C: IgM; D: C3; E: C4; F: C1q; original magnification, x200).
1349-7235-62-0091-g002.jpg
PMC9876725_01_1349-7235-62-0091-g002.jpg
g002
Immunofluorescence staining showed deposits of IgM, C3, and C4 in the glomerular vessels and mesangial area, with no deposits of IgG, IgA, and C1q (Fig. 2).
Findings on electron microscopy of renal biopsy specimens. Electron microscopy revealed electron-dense deposits in the subendothelial area of the glomerular vessel wall (black arrows) and mesangial area (white arrows) (Original magnification, A: x2,000; B-D: x5,000).
1349-7235-62-0091-g003.jpg
PMC9876725_01_1349-7235-62-0091-g003.jpg
g003
Electron microscopy revealed electron-dense deposits in the subendothelial area of the glomerular vessel wall and mesangial area (Fig. 3).