PMC6118332_01
CTV-SR (blue), CTV-HR (orange), and GTV (red) on the simulation CT.. Notes: (A) The CT layer of the upper edge of CTV-SR; combined CTV-SR included PS and LLN-A. (B) The CT layer of the upper edge (rectosigmoid) of GTV; combined CTV-SR included PS, LLN-A, and M; CTV-HR included M around GTV. (C, D) The CT layers of mid-low (C) and low (D) pelvic; combined CTV-SR included PS, posterior LLN-P, LLN-A, and M; CTV-HR included M around GTV. (E, F) The CT layers of the lower edge of CTV-HR (E) and CTV-SR (F); CTV-SR and CTV-HR included M.. Abbreviations: CT, computed tomography; CTV-HR, high-risk clinical target volume; CTV-SR, standard risk clinical target volume; GTV, gross tumor volume; LLN-A, anterior lateral lymph nodes; LLN-P, lateral lymph nodes; M, mesorectum; PS, presacral space.
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The CTV-HR and CTV-SR are shown in Figure 1.
The changes in complete blood count (RBC, WBC, and PLT) depended on the date and treatments (radiation, IL-11, and PLT infusion).. Notes: (A) The changes in RBC, WBC, and PLT depended on the date (days 0-21). (B) 2 Gy radiation on PTV was delivered on days 1-4 and days 7-9. Three milligrams of IL-11 was subcutaneously injected on days 8-12. 1 U PLT was infused on days 10 and 12. (C) The numbers of RBC, WBC, and PLT on different time points.. Abbreviations: IL, interleukin; iv, intravenous; PLT, platelet; PTV, planning target volume; RBC, red blood cell; WBC, white blood cell.
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PMC6118332_01_ott-11-5203Fig2.jpg
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Blood cell changes during treatment are shown in Figure 2.