PMC8492444_01
Neuroradiologic images on preoperatively. Representative axial T1-weighted postgadolinium contrast image (a) and axial T2-weighted FLAIR image (b).
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F1
Magnetic resonance (MR) imaging revealed an enhancing, infiltrative lesion in the left frontal lobe with progressive vasogenic edema in the left pre- and postcentral gyri [Figure 1].
Histopathologic examination of the left frontal lobe lesion brain biopsy (a) and (b) hematoxylin-eosin (H&E, x2) staining shows perivascular inflammatory infiltrates (arrow) and incomplete coagulation necrosis (star), (c) (H&E, x10): perivascular inflammatory infiltrates of atypical medium-sized lymphoid cells and (d) (CD3 immunohistochemical stain, x100 oil): the positive CD3 highlights the nuclear irregularities of the atypical cells and indicates the T-cell lineage of this process.
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F2
Histopathologic evaluation of the biopsy specimen demonstrated a small focus of perivascular lymphocytic infiltrate composed of predominately medium-sized atypical lymphoid cells in a background of histiocytes and small lymphocytes [Figure 2].
Follow-up neuroradiologic images. One-month postoperative representative axial T2-weighted FLAIR image (a), 2-month postoperative representative axial T2-weighted FLAIR image (b), 2-month postoperative representative axial T1-weighted postgadolinium contrast image (c), 4-month postoperative representative axial T2-weighted FLAIR image (d), 1-year postoperative representative axial T2-weighted FLAIR image with appreciated stable FLAIR signal (e), 1-year postoperative representative axial T1-weighted postgadolinium contrast image with no appreciated contrast-enhanced disease (f).
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F3
She had improvement in her aphasia and stability of her T2 fluid-attenuated inversion recovery signal with treatment [Figure 3].