PMC6198579_01
Baseline polysomnogram demonstrated severe obstructive sleep apnea and hypoxemia (a). There was a significant reduction of obstructive events and normalization of oxygenation during AVAPS-AE titration (b). Both figures shown in 2-minute intervals are of rapid eye movement sleep.
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fig1
In-laboratory polysomnography revealed severe OSA, with AHI 138.2, sleep hypoventilation, and hypoxemia (Table 1 and Figure 1(a)). AHI was achieved, with significant improvement in oxygenation, ventilation, and sleep quality (Table 1 and Figure 1(b)). A Trilogy  ventilator (Philips Respironics, Murrysville, PA, USA) was prescribed with AVAPS-AE mode and a nasal mask with the following settings: EPAP 5-16 cm H2O, pressure support 4-17 cm H2O, maximum pressure 25 cm H2O, inspiratory time 1.5 sec, rise time 3, tidal volume 390 ml (8 ml/kg), and breath rate 20/min.