PMC4531574_01
Peripheral blood smear shows markedly increased neutrophils (Wright stain, x200).
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A peripheral blood smear showed microcytic hypochromic anemia, neutrophilic leukocytosis and thrombocytosis (Figure 1).
Bone marrow aspiration smear shows marked granuloytic hyperplasia, with a normal maturation pattern (Wright stain, x400).
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Bone marrow aspiration and a biopsy showed 95% cellularity, with a myeloid:erythroid (M:E) ratio of 10:1, markedly increased granulocytic precursors with normal maturation pattern and 2% myeloblast and increased megakaryocytes with normal morphology, but no evidence of myelofibrosis, and a decreased stainable iron level (Figure 2, 3).
Bone marrow biopsy is hypercellular for her age. Granulocytic precursors are markedly increased. Megakaryocytic precursors are also increased (H & E stain, x200).
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Bone marrow aspiration and a biopsy showed 95% cellularity, with a myeloid:erythroid (M:E) ratio of 10:1, markedly increased granulocytic precursors with normal maturation pattern and 2% myeloblast and increased megakaryocytes with normal morphology, but no evidence of myelofibrosis, and a decreased stainable iron level (Figure 2, 3).
(A) T1-weighted image, (B) T2-weighted image, (C) enhanced T1-weighted image with fat suppression view. diffuse signal change, with mild enhancement of the vertebral body, from the lower thoracic to the lumbar spine.. multiple compression fractures.. posterior protrusion of the T11 body, with spinal cord compression -> these findings are suggestive of leukemic infiltration.. Spine MRI findings are:
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A spine MRI showed compression fractures of the T11, L1,2,4 and leukemic infiltration of the cervical, thoracic, lumbar spine (Figure 4).