PMC3399315_01
(A) Ischemic changes in the upper glomeruli (arrow). Marked subintimal fibromucoid edema narrowing the lumen in the intralobular arterioles (arrows) and (B) duplication of glomerular basement membrane.
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A kidney biopsy was performed and histological studies showed ischemic changes in 12 of 35 glomeruli studied (Figure 1A). Some other glomeruli showed chronic glomerular microangiopathic lesions with duplication of the glomerular basement membrane (Figure 1B). The arterioles and intralobular arteries showed marked subintimal fibromucoid edema narrowing the lumen (Figure 1A arrows, Figure 2A).
(A) Moderate interstitial edema with mild inflammatory cell infiltration and patched tubular atrophy with (B) fibrinogen deposits in the arterial wall in the immunofluorescence study.
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The arterioles and intralobular arteries showed marked subintimal fibromucoid edema narrowing the lumen (Figure 1A arrows, Figure 2A). An immunofluorescence study showed only fibrinogen deposits in the arterial wall (Figure 2B).