PMC126229_01
Intravenous urography (24/07/2000) -3 hours and 40 minutes film shows very faint opacification of right renal pelvis; left renal pelvis is slightly dilated. Bladder outline is irregular on the right side.
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F1
The bladder outline was noted to be abnormal. (Figure 1).
PMC126229_02
Urinary cytology (05/07/2001): Section of the clot present in the specimen contains a cluster of mildly atypical transitional cells interpreted as showing regenerative changes only, surrounded by purulent exudate.
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F2
Urinary cytology (05/07/2001) revealed occasional small clusters of transitional cells and these showed mild atypia consistent with regenerative or inflammatory atypia. (Figure 2).
Repeat ultrasound of urinary bladder (04/07/2001) shows 8 cm x 6 cm tumour arising from the floor and right lateral wall, which on colour Doppler imaging was seen to be moderately vascular.
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F3
A repeat ultrasound scan of urinary bladder (04/07/2001) demonstrated an 8 x 6 cm diameter tumour arising from the floor and right lateral wall, which on colour Doppler imaging was seen to be moderately vascular. (Figure 3).
Haematoxylin & eosin staining of tumour biopsy showed well-differentiated invasive squamous carcinoma, keratinising in areas
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F4
Histopathology revealed necrotic, keratinising, invasive, moderately differentiated, squamous carcinoma of the bladder. (Figure 4).
PMC126229_03
Immuno-histochemistry for G-CSF was performed in the Kidney Disease Centre, Saitama Medical School, 38 Morohongo, Moroyamamachi, Iruma, Saitama 3500495, Japan. There is positive immunostaining for G-CSF in neoplastic cells.
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F5
Figure 5 represents immuno-histochemistry for G-CSF, which was carried out in the Kidney Disease Centre, Saitama Medical School, 38 Morohongo, Moroyamamachi, Iruma, Saitama 3500495, Japan.
Immuno-histochemistry for G-CSF was performed in Department of Pathology, Saiseikai Central Hospital, Minatoku, Tokyo, Japan. There is positive immunostaining for G-CSF in tumour cells.
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F6
Figure 6 shows immuno-histochemistry for G-CSF, which was performed in Department of Pathology, Saiseikai Central Hospital, Minatoku, Tokyo, Japan.
Immuno-histochemistry for PTHrP was performed in the Kidney Disease Centre, Saitama Medical School, 38 Morohongo, Moroyamamachi, Iruma, Saitama 3500495, Japan. There is positive immunostaining for C-terminal PTHrP in neoplastic cells.
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F7
Figure 7 shows immuno-histochemistry for PTHrP, which was carried out in the Kidney Disease Centre, Saitama Medical School, 38 Morohongo, Moroyamamachi, Iruma, Saitama 3500495, Japan.
Immuno-histochemistry for PTHrP was performed in Department of Pathology, Saiseikai Central Hospital, Minatoku, Tokyo, Japan. There is faintly positive immunostaining for C-terminal PTHrP in tumour cells.
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F8
Figure 8 represents immuno-histochemistry for PTHrP, which was performed in Department of Pathology, Saiseikai Central Hospital, Minatoku, Tokyo, Japan.
PMC126229_04