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(A and B) Images of two inflated balloons with a sterile physiological salt solution. (C and D) T2-weighted magnetic resonance images were obtained after two inflated balloons with sterile physiological salt solution filled the double vagina.
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For ICBT, to show the shape of the vagina, two inflated balloons with sterile physiological salt solution filled the double vagina for MRI (Figure 1A and B). As shown in Figure 1C and D, MRI was used to create a 3D-printed ICBT applicator. 
(A) Photographs of the three-dimensional (3D)-printed applicators. (B) Catheters with copper sulfate were placed in two 3D-printed applicators. (C and D) T2-weighted magnetic resonance images were obtained after the catheters with copper sulfate were placed in two 3D-printed applicators. The catheters with copper sulfate are represented by blue arrows.
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Examples are shown in Figure 2A. As shown in Figure 2B, catheters with copper sulfate were placed in two 3D-printed applicators to show the needle paths in the applicators. As shown in Figure 2C and D, a planning MRI scan was performed.
(A and B) Vaginal apex treatment plans using a multichannel cylinder (MCC) and 3D printer. (C and D) Midvaginal treatment plans using MCC and 3D-printer.
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CTV from the vaginal apex, the isodose curve of 100% cover was better than that in the MCC plan. Figure 3C and D show a 100% isodose curve covering a larger volume range of the urethra and rectum, respectively. Comparing the two groups of plans, these results favor the 3D-printed plan.