PMC3369528_01
Endomyocardial biopsy 7 months after transplant showing graft vasculopathy. Endomyocardial biopsy demonstrating microscopic changes of concentric intimal proliferation and chronic inflammation resulting in near-total luminal occlusion in the epicardial and the intramyocardial coronary vessels, suggestive of graft vasculopathy. Hematoxylin and eosin stain: (a) low power, (b) high power, and (c) C4d immunostaining. Immunoperoxidase with C4d monoclonal antibody negative.
CRIM2012-734074.001.jpg
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fig1
A postmortem analysis revealed microscopic changes of concentric intimal proliferation and inflammation resulting in near-total luminal occlusion in the epicardial and the intramyocardial coronary vessels, suggestive of graft vasculopathy (Figures 1(a)-1(c)).