PMC8046933_01
Intraoral photograph at the first visit in case 1, showing a white lesion on the left side of the tongue.
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F1
At her first visit to our clinic, no abnormalities were found in the oral cavity, except leukoplakia on the lateral border of the left tongue (Figure 1). We then referred her to the oral surgery department, where incisional biopsy (Figure 2) from the white lesion (indicated in Figure 1) yielded a diagnosis of oral squamous cell carcinoma (OSCC).
Pathological image in case 1. Hematoxylin and eosin staining of the biopsy specimen revealed tumor islands beneath the epithelium surface.
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F2
We then referred her to the oral surgery department, where incisional biopsy (Figure 2) from the white lesion (indicated in Figure 1) yielded a diagnosis of oral squamous cell carcinoma (OSCC).
PMC8046933_02
T2-weighted axial magnetic resonance imaging in case 2, showing a 37 x 23-mm mass under the floor of the mouth.
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F3
Magnetic resonance imaging (MRI) revealed a 37 x23-mm mass under the right side of the floor of the mouth and enlargement of lymph nodes on both sides (Figure 3).
PMC8046933_03
T2-weighted axial magnetic resonance imaging in case 3, showing a 12 x 12-mm mass on the mandible with bone absorption and a 38 x25-mm mass on the right side of the oral floor.
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F4
MRI later revealed a 12 x12-mm mass on the mandibular anterior region with bone absorption and a 38 x25-mm mass on the right side of the oral floor (Figure 4).