PMC8114248_01
Poorly differentiated mucinous adenocarcinoma (black arrows) invading through the muscularis propria.
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A 75-year-old White female with history of stage IIIB (PT4a,PN2b,M0; 25/26 lymph nodes positive) poorly differentiated mucinous colon cancer (Figure 1) was admitted for back pain.
Cytokeratin staining of the bone marrow, positive for CK20 as well as CDX2 and negative for CK7 suggesting metastatic carcinoma.
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The malignant epithelioid infiltrate showed expression of CK20 and CDX2 and lack of CK7 expression, consistent with metastatic colorectal carcinoma (Figure 2).