PMC9731837_01
Palmar keratoderma. Clinical image of distal digital peeling and hyperkeratosis of the bilateral palms attributed to talquetamab treatment.
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PMC9731837_01_gr1.jpg
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Physical examination revealed desquamating, hyperkeratotic plaques on bilateral palmoplantar surfaces (Figs 1 and 2), proximal separation of the nail plate from the nail matrix on all 20 nails (Fig 3), and diffuse xerosis of the back.
Plantar keratoderma. Clinical image of bilateral thickened soles and peeling due to talquetamab treatment.
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PMC9731837_01_gr2.jpg
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Physical examination revealed desquamating, hyperkeratotic plaques on bilateral palmoplantar surfaces (Figs 1 and 2), proximal separation of the nail plate from the nail matrix on all 20 nails (Fig 3), and diffuse xerosis of the back.
Onychomadesis. Clinical images of the hands demonstrating onychomadesis of all digits and diffuse xerosis of the dorsal surfaces of the hands after starting treatment with talquetamab.
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PMC9731837_01_gr3.jpg
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Physical examination revealed desquamating, hyperkeratotic plaques on bilateral palmoplantar surfaces (Figs 1 and 2), proximal separation of the nail plate from the nail matrix on all 20 nails (Fig 3), and diffuse xerosis of the back.