PMC10123363_01
Pancreatic protocol CT scan showing pancreatic head lesion (marked in semicircular blue) causing dilatation of CBD. Lesion is placed between MPD (marked in linear blue) and CBD.
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F1
No suspicious lymph nodes or free fluid was noted, and there was no evidence of vascular or locoregional spread. (shown in Fig. 1).
Histopathology and immunohistochemistry of MINEN. a High power (x40) (H&E); tumor cells arranged in glandular pattern suggestive of adenocarcinoma component. b High power (x40) (H&E); tumor cells arranged in nesting pattern suggestive of NEN component. c Low power (x10); adenocarcinoma component of tumor strongly highlighted by PanCK immunohistochemistry marker. d Low power (x10); NEN component of tumor strongly highlighted by synaptophysin immunohistochemisty marker. e High power (x40); NEN component of tumor highlighted by chromogranin. f High power (x40); Ki 67 index <1%.
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F2
IHC staining showed that the tumor cells are synaptophysin+, chromogranin+, and PanCK+, and Ki 67 index was <2% (shown in Fig. 2a-d, f).