PMC3125662_01
Clinical picture of ectomesenchymal chondromyxoid tumor presenting as a submucosal swelling on the anterior dorsum of the tongue (a, frontal view; b, lateral view)
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On oral examination, a solitary well defined nodule measuring 1.5 cm in diameter located on the right side of the dorsum of the anterior two third of the tongue, approximately 1 cm from the tip and 1cm from the lateral border was seen [Figure 1].
Gross specimen cut surface showing a well-circumscribed soft tissue lesion
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The cut surface was white in color and well circumscribed [Figure 2].
Photomicrograph shows a nonencapsulated but well circumscribed with lobular pattern of arrangement of the tumor (H and E, x4)
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Histopathologically, on low-power magnification, the lesion was well circumscribed but unencapsulated showing a lobular growth pattern [Figure 3].
Photomicrograph shows lesional cells arranged in a net-like pattern in a myxoid background (H and E, x40)
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On higher magnification, the lesional cells were arranged in the form of cords and strands in a net-like pattern against a myxoid background [Figure 4].
Photomicrograph shows lesional cells infiltrating the striated muscle bundles (H and E, x20)
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However, the lesional tissue was strongly positive for Vimetin [Figure 5] and focally positive for smooth muscle actin (SMA).