PMC10084862_01
Clinical appearance of the patient before treatment. His head, face (A), torso, and limbs (B) can be seen as extensive, well-defined, round patches of erythema covered with thick, greasy yellow scales, similar to oyster shells.
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Physical examination revealed generalized firmly demarcated erythematous circular plaques covered with thick adherent greasy yellowish scales resembling oyster shells over his scalp, face, trunk, upper and lower extremities, groin, and buttocks (Figure 1A and B).
Histopathology of ostraceous psoriasis, psoriasiform hyperplasia of the epidermis with confluent parakeratosis, neutrophils infiltration in the stratum corneum, and moderate amount lymphocyte and neutrophils around small vessels in the superficial dermis (Hematoxylin-eosin, magnificationx100).
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HIV, hepatitis, syphilis and other related laboratory screenings showed no obvious abnormalities, except for elevation of C-reactive protein levels (12.00 mg/L). Histopathology revealed psoriasiform hyperplasia of the epidermis with confluent parakeratosis, neutrophils infiltration in the stratum corneum, and a moderate amount of lymphocytes around small vessels in the superficial dermis (Figure 2).
The skin lesions on the patient's face (A), trunk, and limbs (B) have improved significantly after 18 weeks of treatment.
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After 18 weeks of treatment and stopping of LC, there was a marked improvement (Figure 3A and B).