PMC8666486_01
Endoscopic and pathologic findings in duodenum. (A) Endoscopy shows loss of mucosal folds. (B) Severe atrophic duodenitis. (C) Duodenal biopsy specimen showing subtotal villous atrophy and crypt hyperplasia (H&E, 100x). (D) Histologic changes in the duodenum characteristic of increased intraepithelial lymphocytosis and a chronic inflammatory infiltrate in the lamina propria (H&E, 200x).
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The results of histopathologic findings from random duodenal biopsies revealed subtotal villous atrophy, crypt hyperplasia, and increased intraepithelial lymphocytes, shown in Figure 1.
Intermittently scanned continuous glucose monitoring (isCGM) recorded through 14-day showed time-in-range (70-180 mg/dL) at 69% after a strict gluten-free diet for 3 months.
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As shown in Figure 2, the time-in-range (70-180 mg/dL, 3.9-10.0 mmol/L) was achieved at 69% and time spent in hypoglycemia (less than 70 mg/dL, 3.9 mmol/L) was at only 3%.