PMC5021770_01
Case 1. Computed tomography (CT) reveals an anterior mediastinal tumor, 40 mm in diameter.
gr1.jpg
PMC5021770_01_gr1.jpg
fig0005
Tumor diameter had grown from 30 mm to 40 mm (Fig. 1).
(a) Small-cell carcinoma with hematoxylin and eosin (HE) stain. (b) Immunohistochemistry with CD56 shows thymoma comprising 80% of the tumor and small-cell carcinoma comprising 20%.
gr2.jpg
PMC5021770_01_gr2.jpg
fig0010
Results for neuron-specific enolase (NSE), synaptophysin, and CD56 were positive in the small cell carcinoma and negative in the thymoma on immunohistochemistry (IHC) (Fig. 2).
PMC5021770_02
CT reveals an anterior mediastinal tumor 47 mm in diameter, invading the superior vena cava.
gr3.jpg
PMC5021770_02_gr3.jpg
fig0015
We suspected tumor invasion to the right phrenic nerve, right atrium, and superior vena cava (Fig. 3), and preoperative radiotherapy (total 40 Gy) was therefore selected.
Type B3 thymoma within squamous cell carcinoma.
gr4.jpg
PMC5021770_02_gr4.jpg
fig0020
III), pT3N0M0 WHO stage III. In this case, the type B3 thymoma was slightly observed within the squamous cell carcinoma (Fig. 4).