PMC3325737_01
Chest computed tomography: Admission CT displaying diffuse hazy opacities in both lung fields with occasional nodular formation.
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F1
Repeat CT-CAP defined diffuse hazy opacities in both lungs, hepatosplenomegaly and mild thickening of the walls of the cecum and ascending colon (Figure 1).
Chest computed tomography: Day 3 CT displaying interval increase in bilateral nodular opacities, air bronchograms and pulmonary edema.
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F2
On repeat CT of the chest three days later, there was interval increase in the bilateral nodular opacities, air bronchograms, subcutaneous anasarca and findings consistent with pulmonary edema (Figure 2).
Capillary wall congestion with large atypical lymphocytes and diffuse hemorrhage. Hematoxylin and eosin stain, intermediate magnification.
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F3
Histological examination showed capillary wall congestion with large; atypical lymphocytes (Figure 3).
Lymphocytes displaying vesicular nuclei, prominent nucleoli and frequent mitotic figures. Coarse nuclear chromatin and indented nuclei noted as well. Hematoxylin and eosin stain, intermediate magnification.
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F4
On higher magnification, lymphocytes displayed vesicular nuclei, prominent nucleoli and frequent mitotic figures (Figure 4). Some cells showed coarse nuclear chromatin or irregular and indented nuclei (Figure 4).
Tumor cell staining with B cell marker CD-20. High power magnification.
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F5
Staining with common leukocyte antigen and B cell marker CD-20 exhibited strong uptake by neoplastic cells (Figure 5).