PMC10020938_01
a Initial findings: 12 x 10 x 7 mm nodule on the right upper eyelid. b The tumor showed shrinkage after skin biopsy. c Histological finding (Hematoxylin and eosin staining (H & E) stain x4): epithelial hyperplasia with formation of pseudokeratinocyst within the epidermis and cells of high N/C ratio. d Initial findings: 8-mm-sized dark purple nodule with central keratinization on the right lower eyelid. e Histological finding (H & E stain x4): pseudokeratinocyst formation in the epidermis and an inflammatory cell infiltrate consisting mainly of mononuclear cells in the upper dermis. f The clinical images of typical keratoacanthoma case. g The clinical images of typical seborrheic keratosis case.
cde-2023-0015-0001-529728_f1.jpg
PMC10020938_02_cde-2023-0015-0001-529728_f1.jpg
F1
An 8-mm-sized dark purple nodule with central keratinization was detected (Fig. 1d). The histology of the biopsy showed pseudokeratinocyst formation in the epidermis and inflammatory cells consisting mainly of mononuclear cells in the upper dermis, which was suspicious of seborrheic keratosis (Fig. 1e).
PMC10020938_02
a Initial findings: 12 x 10 x 7 mm nodule on the right upper eyelid. b The tumor showed shrinkage after skin biopsy. c Histological finding (Hematoxylin and eosin staining (H & E) stain x4): epithelial hyperplasia with formation of pseudokeratinocyst within the epidermis and cells of high N/C ratio. d Initial findings: 8-mm-sized dark purple nodule with central keratinization on the right lower eyelid. e Histological finding (H & E stain x4): pseudokeratinocyst formation in the epidermis and an inflammatory cell infiltrate consisting mainly of mononuclear cells in the upper dermis. f The clinical images of typical keratoacanthoma case. g The clinical images of typical seborrheic keratosis case.
cde-2023-0015-0001-529728_f1.jpg
PMC10020938_02_cde-2023-0015-0001-529728_f1.jpg
F1
An 8-mm-sized dark purple nodule with central keratinization was detected (Fig. 1d). The histology of the biopsy showed pseudokeratinocyst formation in the epidermis and inflammatory cells consisting mainly of mononuclear cells in the upper dermis, which was suspicious of seborrheic keratosis (Fig. 1e).