PMC3997243_01
Multiple, non-ulcerated nodules and plaques on the right ear. [Copyright:  2012 Talhari et al.]
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Physical examination revealed ill-defined, smooth, shiny, hard nodules on his right ear (Figure 1).
Diffuse granulomatous infiltrate involving the entire dermis (Haematoxilin and eosin [H&E], original magnification: 20X). [Copyright:  2012 Talhari et al.]
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Histopathologic examination showed a diffuse granulomatous infiltrate involving the entire dermis, constituted by histiocytes and multinucleated giant cells (Figures 2, 3).
The histiocyte's cytoplasm contains rounded yeast-like hyaline cells with a thick double birefringent membrane. These cells are forming chains of multiple organisms. (H&E, original magnification: 400X). [Copyright:  2012 Talhari et al.]
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Histopathologic examination showed a diffuse granulomatous infiltrate involving the entire dermis, constituted by histiocytes and multinucleated giant cells (Figures 2, 3).
The Grocott-Gomori methenamine-silver nitrate stain shows chains of darkly pigmented, spheroidal, yeast-like organisms (original magnification: 200X). [Copyright:  2012 Talhari et al.]
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The Grocott-Gomori methenamine-silver nitrate stain allowed better visualization of chains of darkly pigmented, spheroidal, yeast-like organisms (Figure 4).