PMC7436782_01
Skin biopsy histopathology revealing lichen planus type-drug reaction-atrophic variant.. (A) Compact orthokeratosis; (B) Homogeneous eosinophilic bodies (Civatte bodies) present in the epidermis and at dermoepidermal interface; (C) Thin atrophic epidermis with leukocytosis; (D) Vacuolar alteration at the dermoepidermal interface; (E) Superficial lymphohistiocytic infiltrate; (F) melanophages.. ADRs, adverse drug reactions; ER, emergency room.
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PMC7436782_01_10.1177_2042098620937884-fig1.jpg
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Pathology report (Figure 1) revealed compact orthokeratosis, a thin atrophic epidermis with leukocytosis, and chronic interface dermatitis with superficial lymphohistiocytic inflammatory infiltrate with melanophages that extended focally to the mid-dermis level.
Timeline review of patient case.. ADRs, adverse drug reactions; ER, emergency room.
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PMC7436782_01_10.1177_2042098620937884-fig2.jpg
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For graphic representation, a timeline review of the patient case is shown in Figure 2.