PMC3564573_01
HRCT with big pneumothorax in the left lower hemithorax (red cross).
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F1
Chest computed tomography (CT) showed the presence of an extended pneumothorax over the lower lobe of the left lung (Fig. 1).
A. Lesional cells are perivascular and consist of polygonal and oval/spindle cells with amphophilic cytoplasm. (H + E, original magnification 200 x); B. Lesional cells show focal staining with antibody to HMB 45 antigen; C. Lesional cells show staining with antibody to estrogen receptors; D. Lesional cells show staining with antibody to progesterone receptors.
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F2
Biopsies of lung tissue showed positive immunoreactivity with monoclonal antibody HMB-45 confirming the diagnosis of LAM (Fig. 2).
CT scan at follow up (4 months postoperatively).
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F3
Follow-up CT scans at 4 months showed a moderate pleural thickening, residual pulmonary cysts on the left side and no evidence of pneumothorax (Fig. 3).