PMC3938374_01
Macular, confluent, pruritic lesions in the abdomen and arms of a 26 weeks
pregnant woman
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A 27-year-old woman at 28-weeks gestation presented with a widespread, pruritic eruption of macular, confluent lesions with tense vesicles and some blisters in the arms and thighs (Figure 1).
Cutaneous biopsy in lesional skin revealed a marked edema that outlined a
dermal-epidermal detachment, with a dense inflammatory infiltrate (predominantly
with eosinophils) extending to the dermis
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In the underlying dermis, a marked edema outlined a dermal-epidermal detachment, with a dense inflammatory infiltrate (predominantly with eosinophils) extending to the dermis (Figure 2).
Direct immunofluorescence in perilesional noninvolved skin showed linear deposists
of C3 at the basement-membrane zone
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Direct immunofluorescence in perilesional noninvolved skin showed linear deposists of C3 at the basement-membrane zone (Figure 3).