PMC3742359_01
A tumor with cystic regions of many sizes with solid parts, and adipocyte-laden parts.
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The tumor is a mass with cystic regions of many sizes, with solid parts and adipocyte-laden parts (Fig. 1).
Pathological findings. (A) Immature neuroectodermal tissue in the first operation (x40 H&E). (B) Immature neuroectodermal tissue in the first operation (x400 H&E). (C) Gliomatosis peritonei in the first operation (x100 H&E). (D) GFAP expression in gliomatosis peritonei in the first operation. (E) GFAP expression in gliomatosis peritonei in the second operation. (F) Immature teratoma grade 1 in the third operation (x100 H&E). (G) GFAP expression in gliomatosis peritonei in the third operation. (H) GFAP expression in gliomatosis peritonei in the fourth operation. (I) GFAP expression in the glial implant in lymph node in the fourth operation.
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Pathologically, the mass contained squamous epithelium, adipose tissue, bone and cartilage tissue, and immature neuroectodermal tissue, and was therefore classified as a grade 2 immature teratoma (Fig. 2A and B). Peritoneal lesions, which were composed of mature glial cells, were diagnosed as gliomatosis peritonei using hematoxylin and eosin (H&E) stain (Fig. 2C). Immunohistochemically, the glial cells were positive for glial fibrillary acidic protein (GFAP), which is expressed by numerous cell types of the central nervous system, including astrocytes, ependymal cells and glial cells (Fig. 2D). Pathological diagnosis was mature cystic teratoma of left ovary and gliomatosis peritonei (Fig. 2E). Pathologically, the mass contained immature neuroectodermal tissue, and so was classified as a grade 1 immature teratoma and gliomatosis peritonei (Fig. 2F and G). The pathological diagnosis was endometrial cyst of left ovary, gliomatosis peritonei and glial implant in lymph node (Fig. 2H and I).