PMC3304081_01
Photograph of a 3 mm polyp of the transverse colon, found on biopsy to be a neurofibroma.
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F1
On colonoscopic examination, a 3 mm polyp was found in the transverse colon (fig. 1) and another 4 mm polyp in the descending colon; both were biopsied.
Photomicrograph of a transverse colon polyp. A high-power field showed interlacing bundles of spindle cells, with comma-shaped nuclei, extending into the lamina propria, consistent with findings of a neurofibroma. Staining was positive for nuclear S100.
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F2
Histological examination of the descending colonic polyp revealed findings consistent with a tubular adenoma; however, multiple levels of the 3 mm transverse colon polyp revealed interlacing bundles of spindle cells extending into the lamina propria with comma-shaped nuclei consistent with findings seen in neurofibroma (fig. 2).