PMC8575694_01
Computed tomography Imaging Computed tomography scan showing a mixed solid and cystic hypodense mass in the tail of the pancreas measuring 35 x 37 mm in the maximum diameter (A); Contrast-enhanced CT imaging showing the mass with obvious enhancement (B).
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F1
It adjoined the hilum of the spleen (Figure 1).
Magnetic Resonance Imaging Magnetic Resonance of abdominal revealed a mass in the tail of the pancreas. T1-weighted images is low signal (A) and T2 -weighted images is high signal (B); Contrast-enhanced spin-echo T1-weighted MRI showed the lesion obvious enhancement (C); The tumor showed restricted diffusion on Diffusion-Weighted imaging (D).
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F2
The mass was low signal on T1-weighted images (Figure 2A) and high signal on T2-weighted images (Figure 2B). T1-weighted MRI showed the lesion obvious enhancement (Figure 2C). The tumor showed restricted diffusion on Diffusion-Weighted imaging (Figure 2D).
Histopathological and Immuno-histochemical images Low power image (HE x 40) of the carcinoma with squamous cell (A); Higher power image with large squamous cell carcinoma nest and characterized by typical keratin pearls in histopathological assessments, without glandular component (B). Immuno-histochemical showed p63 (+), p40 (+), and P63 and P40 as specific marker of squamous cell carcinoma (C,D).
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F3
On histopathological assessment, the mass was composed of large squamous cell carcinoma nests and characterized by the typical keratin pearls morphology (Figure 3A). The results revealed a well-differentiated SCCP with abundant cytoplasm and no glandular component (Figure 3B). Immuno-histochemical analysis showed CK-high (+), CK-low (+), CK5/6 (+), P63 (+), and P40 (+) (Figures 3C,D).