PMC5565258_01
Subungual hyperkeratosis (arrow) (A, B), onycholysis, onychomadesis, and a transparent serous exudate emanating from the toenail bed (circle) (A).
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Examination of the patient revealed toenail changes including subungual hyperkeratosis, onycholysis, onychomadesis, and a transparent serous exudate emanating from all the nail beds (Figure 1).
The patient's hands became desquamated and red (B). Fingernail changes included dark pigmentations, Beau's lines, and subungual hyperkeratosis (A).
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Her hands had desquamation and redness, and fingernail changes included dark pigmentations, Beau's lines, and subungual hyperkeratosis (Figure 2).
Dysesthesia symptoms remained, and all the toenails exhibited defects (arrow) (A) or deformities (circle) (A, B) at a 24-month follow-up.
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The dysesthesia symptoms remained, and all the toenails exhibited defects or deformities (Figure 3); however, her hands returned to normal and her fingernails improved at a 24-month follow-up (Figure 4).
The patient's hands returned to normal (B). Fingernail changes improved at a 24-month follow-up (A).
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The dysesthesia symptoms remained, and all the toenails exhibited defects or deformities (Figure 3); however, her hands returned to normal and her fingernails improved at a 24-month follow-up (Figure 4).