PMC7354669_01
Overview of HeartLogic general evolution and contributing trends. Here, the general evolution of HL parameters is shown with a rapid and steep increase in the last seven days. It is observed that the third heart sound (S3), respiratory frequency, and nightly heart rate contribute to the increased HL index. Also, surprisingly, thoracic impedance rapidly increases. In contrast, heart rate variability and activity level significantly decreased. Also, due to the increased respiratory frequency, the number of apneas decreased.
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Concordant with the euvolemic state, the HeartLogic (HL) index was consistently under the threshold level for more than 6 months (Figure 1). Seven days before admission, however, the HL index started to rise extremely fast, starting from a value of 9 till a HL index of 63 on the day of presentation at the emergency department. (Figure 1, Supplemental Figure (available here).
Overview of thoracic CT-scan revealing important COVID-19 disease. The arrows show the bilateral multifocal subpleural ground glass opacities, peribronchovascular infiltrates with partial consolidation, and thin pleural strands in both lower lobes.
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No pulmonary edema and no pleural effusion were observed (Figure 2).