PMC8348509_01
Findings on chest X-ray and dynamic computed tomography (CT) before corticosteroid treatment. (a) Chest radiography shows reduced permeability in the left lower lung field. (b, c) Dynamic chest CT shows a pleural effusion with passive atelectasis and pleural thickness on the left side.
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Chest radiography showed decreased permeability in the left lower lung field (Fig. 1a), and dynamic chest computed tomography showed a pleural effusion with passive atelectasis and pleural thickening on the left side (Fig. 1b and c).
Histological findings of the pleural specimen and bone marrow. (a) Histological examination of the pleural specimen shows eosinophilic infiltration with inflammatory granulation tissue without fibrinoid necrosis or malignant cells (x200). (b) Histological examination of the bone marrow shows normocellular marrow with 10% eosinophils in nucleated cells, with no maturity disorder of granulocytes and no increase of hemocytoblasts (x200).
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A thoracoscopic pleural biopsy was performed, and eosinophilic infiltration with inflammatory granulation tissue was seen without fibrinoid necrosis or malignant cells (Fig. 2a). To rule out a myeloproliferative disorder, a bone marrow biopsy was performed, and normocellular marrow with 10% eosinophils in nucleated cells, with no maturity disorder of granulocytes and no increase of hemocytoblasts, was seen (Fig. 2b).
Findings on chest X-ray after 3 months of corticosteroid treatment. (a) Chest radiography shows that the pleural effusion on the left side has disappeared after treatment.
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His pleural effusion disappeared 3 months after treatment (Fig. 3a).