PMC8094150_01
A) Lateral view of subcutaneous myxoma (arrowhead) in a 3-year-old bearded dragon; B) Bearded dragon after the surgery of mass, Scale bar = 1.00 cm
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F1
A female bearded dragon (Pogona vitticeps) with a raised mass on the left side of the body was referred to the Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran (Fig. 1A). The bearded dragon was recovered uneventfully (Fig. 1B).
A
) Hypocellular mass with spindle-shaped and stellate cells scattered within a mucopolysaccharide myxoid matrix (H&E, Scale bar = 100 microm. Inset: High magnification of spindle-shaped cells in a myxoid matrix (H&E, Scale bar = 20.00 microm), B) Myxoid cells display a periodic acid Schiff positive cytoplasm (arrowheads), (PAS, Scale bar = 20.00 microm).
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F2
Stellate-to-reticular cells distributed in a mucinous stroma containing few tiny blood vessels were seen (Fig. 2A). Myxoid cells displayed a PAS positive cytoplasm and round to oval nuclei and the stroma was stained pale positive with PAS, indicating the presence of glycosaminoglycan in the myxoid mass (Fig. 2B).
The intercellular myxoid matrix (arrowheads) is alcianophilic at the pH of 2.50 (Alcian blue, Scale bar = 20.00 microm)
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F3
The myxomatous matrix was alcianophilic at the pH of 2.50 (Fig. 3).