PMC4074181_01
PMC4074181_02
Contrast-enhanced CT revealed hepatomegaly and heterogeneity of contrast staining.. Notes: (A) Plain phase. (B) Early phase. Narrow intrahepatic portal vessels are shown (white arrow). (C) Late phase. Hepatic vessels are unclear. (D) FDG-PET/CT revealed heterogeneous uptake of FDG into the liver. SUV maximum range was: 3.2-3.7; 2.8-3.2; and 1.6-2.5 in the left, right lobes of the liver, and the spleen, respectively.. Abbreviations: CT, computed tomography; FDG, fluorodeoxyglucose; PET, positron emission tomography; SUV, standard uptake value.
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Contrast-enhanced computed tomography (CT) revealed hepatomegaly with narrow portal vein, hepatic vein, and mild splenomegaly (Figure 1A-C). The FDG uptake into the liver but not into the spleen was observed (Figure 1D), although the mean standard uptake value was not so high (2.0 in the left lobe of the liver; 1.8-2.0 in the right lobe; and 1.3-1.4 in the spleen).
MRCP (A) and ERCP (B and C) revealed narrowed whole intrahepatic bile ducts with smooth walls (white arrows).. Abbreviations: MRCP, magnetic resonance cholangiopancreatography; ERCP, endoscopic retrograde cholangiopancreatography.
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Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography revealed narrowed intrahepatic bile ducts with smooth walls (Figure 2).
Liver biopsy showing deposition of amyloid protein.. Notes: Hematoxylin and eosin stain, original magnification 20x (A) and 100x (B); Congo red stain, 20x (C) and 100x (D).
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The specimen was occupied by a diffuse eosinophilic amorphous structure, and any cellular component could not be found, suggesting hepatic amyloidosis (Figure 3).