PMC6340242_01
Clinical photograph of the left axilla with a nodular mass
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F1
We present a case of 65-year-old male presented to the general surgery outpatient department for the evaluation of a painless, superficial nodular mass in the left axilla that had slowly grown over a period of 2 years and measured 8 cm x 6 cm [Figure 1].
Microphotograph showing tumor cells floating in pools of mucin (H and E, x200)
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F2
The smears were hypercellular, tumor cells forming cohesive clusters, isolated scattered singly, and at places forming a vague acinar pattern against the mucoid background [Figure 2].
Microphotograph showing solid tubular and cribriform arrangement of the tumor cells floating in the pools of mucin (H and E, x40)
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F3
Nodules were composed of small clusters, islands of tumor cells with cribriform pattern floating in pools of mucin [Figure 3].
Microphotograph showing tumor cells with apocrine differentiation (H and E, x100)
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F4
Focal apocrine differentiation was also noted [Figure 4].
Microphotograph showing tumor cells positive for cytokeratin 7 (CK7, x40)
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F5
The neoplastic cells were strongly positive for cytokeratin 7 (CK7) [Figure 5] and negative for CK20.
Microphotograph showing periodic acid-Schiff positive with diastaseresistant mucin (periodic acid-Schiff with diastase, x40)
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F6
The mucin was periodic acid-Schiff positive and diastase resistant [Figure 6] and alcian blue positive at pH of 2.5 [Figure 7] and negative at pH of 1.
Microphotograph showing alcian blue positive mucin at pH 2.5 (Alcian blue, x40)
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F7
The mucin was periodic acid-Schiff positive and diastase resistant [Figure 6] and alcian blue positive at pH of 2.5 [Figure 7] and negative at pH of 1.