PMC5787658_01
CT showing hypodense mass occupying right thyroid gland, across the isthmus to the left thyroid lobe with a ring calcification feature on right lobe
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F1
Computed tomography (CT) scan revealed the presence of a thyroid mass involving bilateral lobes and isthmus with bilateral cervical lymphadenopathy (Fig.1) with evidence of lung metastases (Fig.2). 
Cohesive malignant cells arranged in sheets, nests, cords, islands and trabeculae pattern [4x, hematoxylin and eosin (HE)]. These malignant cells exhibit large, pleomorphic, hyperchromatic to vesicular nuclei with large prominent eosinophilic nucleoli and abundant eosinophilic cytoplasm
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F3
Features of keratin pearls and intercellular bridges. (40x, HE)
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F4
Individual keratinization and intercellular bridges were noted as well as tumor cell spindling (Fig. 4).