PMC6551503_01
Blood smear of the case report- dysgranulopoiesis: hypogranular granulocytes, hypolobation nuclear, and Pseudo Pelger-Huet.
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Manual differential count revealed 60% neutrophiles, 16% metamyelocytes, 8% myelocytes, 2% promyelocytes; 1% Blasts, 3% monocytes, 1% basophilic granulocytes, 2% Eosinophilic granulocytes, 7% lymphocytes, with dysgranulopoisesis showed abnormal nuclear segmentation: hypolobation nuclear, hypersegmentation nuclear, Pseudo Pelger-Huet and hypogranular granulocytes (Fig. 1).
Spinal smear of the case report.
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Then the Bone Marrow Aspirate (BMA) was performed: morphology of BMA showed a hypercellular marrow, with myeloid hyperplasia to 73%, including: myeloblasts 3%, promyelocytes 5%, myelocytes 12%, metamyelocytes 20%, neutrophilic granulocytes 28%, eosinophils 5%, basilophiles 0%, and 4% monocytes, with subtle dysgranulopoiesis (Fig. 2).