PMC8421676_01
Clinical features of our patient with Prader-Willi syndrome (PWS) (2 days after birth). (A) Non-invasive respiratory support with positive end expiratory pressure was used for the treatment of respiratory distress. Overall appearance of the boy indicated no significant difference between the patient and normal infants. Note muscular hypotonia and abnormal position of the hands and feet. (B) Facial features of the boy (narrow forehead, fair eyebrow, bilateral epicanthus, flat nose, big nostrils, and thin upper lip). (C) Overall appearance of abnormal position of the hands and feet. (D) Abnormal position of the fingers with thumbs adducted under index and middle fingers, flexed hands and wrists, persistently clenched hands and arachnodactyly. (E) Small feet and toes. (F) Genital hypoplasia with slight maldescent of the left testis.
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F1
Physical examination revealed weak cry, flat nose, big nostrils, bilateral epicanthus, wide-spaced nipples, long slender fingers, and slight maldescent of the left testis (Figure 1).