PMC4782528_01
Family tree of first family showing affected siblings without involvement of other family members
AIAN-19-119-g001.jpg
PMC4782528_01_AIAN-19-119-g001.jpg
F1
Two out of four of his siblings (one elder and one younger sister) [Figure 1] had similar problem and were wheelchair bound.
PMC4782528_02
Low and high magnification of transversely cut skeletal muscle tissue showing vacuoles in left triceps muscle (second family)
AIAN-19-119-g003.jpg
PMC4782528_02_AIAN-19-119-g003.jpg
F2
A possibility of HIBM was considered and she underwent triceps muscle biopsy which revealed features consistent with HIBM [Figure 2].