PMC6208546_01
Adjusted ORs and 95% CIs of acute pancreatitis during the first 30 days after oral metronidazole exposure.. Notes: ORs and 95% CIs were estimated using subjects not exposed to metronidazole before index date as the reference group. Estimates were adjusted for matching variables (sex, age at index date, and calendar year at index date), inflammatory bowel disease, thiopurine drugs, sulfasalazine, alcohol abuse, cholelithiasis, civil status, education level, country of birth, chronic obstructive pulmonary disease, diabetes, gastrointestinal ulcer, PPIs, H2-receptor blockers, nonsteroidal anti-inflammatory drugs, opioid analgesics, and polypharmacy score.. Abbreviations: CI, confidence interval; OR, odds ratio; PPI, proton pump inhibitor.
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f1-clep-10-1573
As shown in Figure 1, the odds among current users were highest 1-5 days after exposure (OR: 20.47; 95% CI: 8.24-50.85) and decreased thereafter with some random variation.