PMC4778693_01
Computed tomography images. Multiple lymphadenopathies are observed in the hilar and mediastinal lymph nodes (A) and inguinal lymph nodes (B).
can-10-625fig1.jpg
PMC4778693_01_can-10-625fig1.jpg
figure1
Contrast-enhanced computed tomography (CT) scanning showed lymphadenopathies of the hilar, mediastinal, and para-aortic areas, in addition to the submandibular, neck, axillae, and inguinal lymph node swelling (Figure 1).
Oesophagogastroduodenoscopy images. A slight elevation of the mucosa and partial change in the mucosal colour to off-white are observed in the gastric body (A). Close examination (B) and magnified observation (C) showed elongated and distorted microvessels. Magnifying observation with narrow-band imaging revealed that the gastric pits were preserved (D).
can-10-625fig2.jpg
PMC4778693_01_can-10-625fig2.jpg
figure2
A slight elevation of the mucosa and partial change in the mucosal colour to an off-white shade were also observed in the gastric body (Figure 2A). Close examination and magnified observation of the lesion revealed atypical microvessels (Figure 2B and C). Narrow-band imaging showed that the gastric pits were preserved (Figure 2D).
Pathological images. A biopsy examination taken from the gastric lesion revealed dense infiltration of atypical, medium-to-large lymphoid cells (A and B: Haematoxylin and eosin staining). Lymphoma cells were positive for CD3 (C), CD4 (D), and CD5 (E), while they were negative for CD20 (F), CD7 (G), CD8 (H), T-cell intracellular antigen-1, and granzyme B (I). The result of an in situ hybridisation for Epstein-Barr virus-encoded small RNA-1 was negative (J). A,C-J: x10, B: x40.
can-10-625fig3.jpg
PMC4778693_01_can-10-625fig3.jpg
figure3
A biopsy examination taken from the gastric lesion revealed dense infiltration of atypical, medium-to-large lymphoid cells (Figure 3A and B). T-cell intracellular antigen-1, and granzyme B (Figure 3C-I). The result of in situ hybridisation for Epstein-Barr virus-encoded small RNA-1 was negative (Figure 3J). Random biopsy sampling from the gastric antrum and the lesser curvature of the gastric body contained no lymphoma cells.