PMC7326298_01
CT scan of a patient with MTX-associated reversible liver atrophy in a patient with RA. (a) Seven years before hospitalization. (b) Three years before hospitalization. (c) At the time of hospitalization. (d) Ten months after MTX discontinuation.
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CT performed every few years before hospitalization showed gradually progressing liver atrophy (Fig. 1a and b: 7 and 3 years before hospitalization, respectively). CT performed at the time of hospitalization showed severe liver atrophy and ascites (Fig. 1c). The ascites disappeared, and the liver atrophy slowly improved (Fig. 1d).