PMC7527865_01
Oral examination evincing poor oral health status and amelogenesis imperfecta reported at Case-1 (
a and
b); Infiltrative lesion on hard, soft palate and uvula reported at Case-2 (
c); Ulcerated lesions in the lower lip frenulum, reported at Case-3 (
d).
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PMC7527865_03_f1000research-8-29234-g0000.jpg
f1
In 2013, the patient was admitted with submandibular lymphadenopathy and ulcerated lesions in the lower lip frenulum ( Figure 1d), gingiva, nasal septum and in the back region.
PMC7527865_02
Oral examination evincing poor oral health status and amelogenesis imperfecta reported at Case-1 (
a and
b); Infiltrative lesion on hard, soft palate and uvula reported at Case-2 (
c); Ulcerated lesions in the lower lip frenulum, reported at Case-3 (
d).
f1000research-8-29234-g0000.jpg
PMC7527865_03_f1000research-8-29234-g0000.jpg
f1
In 2013, the patient was admitted with submandibular lymphadenopathy and ulcerated lesions in the lower lip frenulum ( Figure 1d), gingiva, nasal septum and in the back region.
PMC7527865_03
Oral examination evincing poor oral health status and amelogenesis imperfecta reported at Case-1 (
a and
b); Infiltrative lesion on hard, soft palate and uvula reported at Case-2 (
c); Ulcerated lesions in the lower lip frenulum, reported at Case-3 (
d).
f1000research-8-29234-g0000.jpg
PMC7527865_03_f1000research-8-29234-g0000.jpg
f1
In 2013, the patient was admitted with submandibular lymphadenopathy and ulcerated lesions in the lower lip frenulum ( Figure 1d), gingiva, nasal septum and in the back region.
PMC7527865_04
Hyperemic and pruritic lesion on the upper lip, reported at Case-4 (
a); Aspect of the upper lip one month later, evidenced remission of lesion (
b).
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PMC7527865_04_f1000research-8-29234-g0001.jpg
f2
He presented worsening of the lesion and Montenegro intradermal examination was performed ( Figure 2a). One month later, patient was discharged with remission of the lesion ( Figure 2b).
PMC7527865_05
Ulcerated oral lesions in hard palate reported at Case-5 (
a). Leishmaniasis lesion in the left malar region reported at Case-6 (
b).
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f3
In June 2012, patient presented with a papule lesion in the left malar region with late ulceration and increasing in size ( Figure 3b).
PMC7527865_06
Ulcerated oral lesions in hard palate reported at Case-5 (
a). Leishmaniasis lesion in the left malar region reported at Case-6 (
b).
f1000research-8-29234-g0002.jpg
PMC7527865_06_f1000research-8-29234-g0002.jpg
f3
In June 2012, patient presented with a papule lesion in the left malar region with late ulceration and increasing in size ( Figure 3b).
PMC7527865_07
Ulcerated lesions in face, marginal gingiva, palate, and labial mucosa, before (
a) and after treatment with liposomal amphotericin B (
b) reported at Case-7.
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f4
Oral cavity clinic-examination showed scattered ulcers on the face, lower labial mucosa, and on the left lip commissure, pseudomembrane on the marginal gingiva, and an exophytic nodule in the left labial mucosa ( Figure 4). After seven days, we accessed the PCR laboratory test and initiated therapy with intravenous liposomal amphotericin B 50 mg at the dose of 200 mg/kg/day for 15 days ( Figure 4).