PMC5842716_01
Family pedigree. Standard pedigree symbols are used. An arrow indicates the proband. The numbers inside the symbols represent the number of family members. The numbers at the right lower side of the symbols represent current age or age at death of the individuals. Asterisks indicate individuals that underwent whole exome sequencing.
CRIG2018-6968395.001.jpg
PMC5842716_01_CRIG2018-6968395.001.jpg
fig1
Upon ascertainment of family history, we found that one of the proband's sisters and his daughter both shared his symptoms of hives and angioedema (Figure 1).