PMC6560958_01
Hemoglobin and reticulocyte from birth until 1 year of age
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At day 3 of life, he was extubated, however, he continued to have decreased hemoglobin (Figure 1) with increased liver transaminases with a peak aspartate aminotransferase (AST) of 238 U/L (normal ranges, 0 to 38U/L) and alanine aminotransferase (ALT) of 169 U/L (normal ranges, 0 to 41 U/L) (Figure 2).
Liver enzymes (ALT and AST) from birth until 1 year of age
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At day 3 of life, he was extubated, however, he continued to have decreased hemoglobin (Figure 1) with increased liver transaminases with a peak aspartate aminotransferase (AST) of 238 U/L (normal ranges, 0 to 38U/L) and alanine aminotransferase (ALT) of 169 U/L (normal ranges, 0 to 41 U/L) (Figure 2). On follow up, bilirubin (Figure 3) and ferritin (Figure 4) levels decreased and normalized at four months of age while liver markers normalized at one year (Figure 2).
Total and direct bilirubin in the first 4 months of life
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Also, total and direct bilirubin continue to increase and reached a peak of 472 umol/L (normal ranges, 0 to 17) and 343 umol/L (normal ranges, 0 to 3), respectively (Figure 3). On follow up, bilirubin (Figure 3) and ferritin (Figure 4) levels decreased and normalized at four months of age while liver markers normalized at one year (Figure 2).
Ferritin level in the first 4 months of life
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Additionally, serum ferritin found to be elevated 6013 ng/L was attributed to repeated blood transfusions (Figure 4). On follow up, bilirubin (Figure 3) and ferritin (Figure 4) levels decreased and normalized at four months of age while liver markers normalized at one year (Figure 2).