PMC5789048_01
Pretreatment radiological imaging.. Notes: (A) Coronal view of enhanced CT. Opacification of the left maxillary sinus, ethmoid sinus, and sphenoid sinus is revealed. (B) Axial view of enhanced CT. The posterolateral wall of the maxillary sinus is invaded and destroyed. (C) Coronal view of T2-weighted imaging. The tumor expands from the maxillary sinus to the common nasal meatus. The ethmoid sinus and nasofrontal duct are filled with secondary sinusitis. (D) Axial view of Gd enhanced T1-weighted imaging. The tumor extends posterior-laterally, invading the medial and lateral pterygoid muscles.. Abbreviation: CT, computed tomography.
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No lymph node swelling was identified (Figure 1A and B). The ethmoid sinus and frontal sinus were filled with high T2 lesions, arousing our suspicion of secondary sinusitis due to the tumor (Figure 1C and D).
(A and B) Hematoxylin-eosin stain revealed spindle cells and small round cells with ovoid hyperchromatic nuclei arranged in cellular sheets. (Original magnification A: x100, B: x400.) Immunohistochemically, the tumor cells were diffusely reactive for TLE1 (C) and INI-1 (D).
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Post-operative histopathological examination revealed spindle cells and small round cells with ovoid hyperchromatic nuclei arranged in cellular sheets (Figure 2A and B). TLE1 (Figure 2C), INI-1 (Figure 2D), Bcl-2, and focally reactive for AE1/AE3, EMA, and desmin.
Magnetic resonance imaging after three courses of ifosfamide and pirarubicin.. Notes: No residual tumor can be identified. (A) Coronal view of Gd-enhanced T1-weighted imaging. (B) Axial view of T2-weighted imaging.
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After three cycles, the tumor was undetectable using fiberscopes and MRI, thus providing a response evaluation of "complete" (Figure 3).