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CT scan demonstrating a contrast-enhancing lesion in the left pre-pontine region, likely to be a trigeminal schwannoma or metastatic deposit.
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CT head revealed a contrast-enhancing lesion in the left pre-pontine region, likely to be a trigeminal schwannoma or metastatic deposit (Fig. 1).
Photograph of cytological slide prepared from CSF (Leishman Giemsa stain, 20x magnification). Image shows atypical large cells with prominent nucleoli, abundant cytoplasm and atypical mitosis. There are also some lymphocytes present.
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CSF results revealed no bacterial, acid-fast-bacilli or fungal growth, viral and TB PCR were negative. CSF cytology showed malignant cells (Fig. 2).
Photograph of histopathological slide prepared from endobronchial biopsy (H&E stain, 20x magnification). Image shows malignant cells with abundant cytoplasm, vesicular nuclei and nucleoli and spindling.
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Histopathological analysis revealed melanoma (cells expressed: S100p, Melan A and HMB45 and were immunonegative for: AE1/3, p63 and TTF1) (Figs 3-5).
Photograph of histopathological slide prepared from endobronchial biopsy (10x magnification):showing positive immunohistochemical staining for S100p
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Histopathological analysis revealed melanoma (cells expressed: S100p, Melan A and HMB45 and were immunonegative for: AE1/3, p63 and TTF1) (Figs 3-5).
Photograph of histopathological slide prepared from endobronchial biopsy (10x magnification):showing positive immunohistochemical staining for Melan A.
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Histopathological analysis revealed melanoma (cells expressed: S100p, Melan A and HMB45 and were immunonegative for: AE1/3, p63 and TTF1) (Figs 3-5).