PMC7732554_01
Endoscopic view: (A) proximal tumor margin; (B) retroflexed view of the cardia.
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F1
An esophagogastroduodenoscopy showed a polypoid ulcerated lesion of the distal esophagus at 31-37 cm from the incisors, ulcerated and suspicion of Barrett's esophagus (Figure 1).
Thoracoscopic view (semi-prone position): huge neoplastic mass involving the infra-carenal esophagus.
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F2
The patient was scheduled for a minimally invasive Ivor Lewis esophagectomy with celiac and mediastinal lymphadenectomy, and intrathoracic anastomosis (Figure 2).
(A) Microscopic findings of the tumor at 5x magnification. Anaplastic large cells showing solid growth pattern and poorly cohesive growth. (B) Higher magnification (20x) view of the solid growth area. White box underlines at 100x magnification tumor cells exhibiting large nuclei with conspicuous nucleoli and eosinophilic "rhabdoid" cytoplasmic inclusions, while the nucleus is displaced eccentrically by the cytoplasmic inclusion body.
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F3
Pathology revealed a poorly differentiated tumor, with morphologic characteristics of rhabdoid tumor, central necrosis and transmural infiltration of the esophageal wall (Figures 3A,B).