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Bone marrow examination showing the diagnosis of pure red cell aplasia after imatinib initiation.
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A repeat bone marrow examination showed PRCA (figure 1).
Bone marrow examination showing the diagnosis of PRCA after nilotinib initiation.
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The repeat bone marrow examination again showed PRCA (figure 2).
Changes in haemoglobin over the course of the treatment in a patient with chronic myeloid leukaemia who developed pure red cell aplasia secondary to imatinib and nilotinib. The effect of each intervention in the haemoglobin count is depicted. Hb, haemoglobin.
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The changes in Hb count parallel to the interventions are depicted graphically in figure 3.