PMC7610031_01
Intussusception seen on CT.
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Ultrasound and computed tomography of the abdomen revealed ileocaecal intussusception (Fig. 1).
Intussusception with tumour within.
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The specimen was cut open and it showed a 1 cm tumour at the ileocaecal junction (Fig. 2).
Mucosal-submucosal tumour with eroded overlying mucosa. The tumour cells form nests and trabeculae (H&E, x40).
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The tumour invaded into the muscularis propria and subserosa (Fig. 3).
The tumour cells have round to oval nuclei with irregular chromatin clumps and small nucleoli. No mitotic activity seen (H&E, x400).
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There was no obvious mitosis identified (mitotic count <1/10 HPF) (Fig. 4).
The tumour cells show diffuse immunoreactivity for Chromogranin A (a), Synaptophysin (b) and CDX2 (c) and focal immunoreactivity for CD56 (d).
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The immunohistochemical studies showed the tumour cells were diffusely positive for CKAE1/AK3, chromogranin, synaptophysin and CDX2 and focally positive for CD56 (Fig. 5).