PMC10040152_01
Ultrasonography and pathology of AMFB. (A) Ultrasound indicates a moderate echo in the mass. (B) The hypercellular areas of cells are alternately distributed with hypocellular areas of cells, and abundant thin-walled small blood vessels are seen (HEx100). (C) The hypercellular areas of cells, tumor cells are distributed in bundles or patches around blood vessels, cells are spindle-shaped, cytoplasmic eosinophilic, and some cells are round or oval and epithelioid in shape (HEx400). (D) One case has slightly abundant tumor cells, and the mitotic phase is visible (about 1-2/10HPF)(HEx400). (E) Vascular endothelial cells CD34(+)(IHCx100). (F) Tumor cell vimentin(+)(IHCx100).
IJWH-15-427-g0001.jpg
PMC10040152_02_IJWH-15-427-g0001.jpg
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The hypercellular areas alternated with hypocellular areas and abundant thin-walled small blood vessels were observed (Figure 1B). In the hypercellular areas, tumor cells, spindle-shaped and cytoplasmic eosinophilia, were distributed in bundles or patches around blood vessels, and some round or oval and epithelioid cells were observed (Figure 1C). The pathological findings also suggested that tumor cells were relatively abundant and mitosis was visible (approximately 1-2/10 HPF) (Figure 1D). On the suspicion of AMFB, the immunohistochemistry indicated the following results: ER (+), PR (+), Vimentin (+), CD34 (+), SMA (+), desmin (-), MSA (-), AE1/AE3 (-), s-100 (-), and Ki67 (+, <5%) (Figure 1E and F).
PMC10040152_02
Ultrasonography and pathology of AMFB. (A) Ultrasound indicates a moderate echo in the mass. (B) The hypercellular areas of cells are alternately distributed with hypocellular areas of cells, and abundant thin-walled small blood vessels are seen (HEx100). (C) The hypercellular areas of cells, tumor cells are distributed in bundles or patches around blood vessels, cells are spindle-shaped, cytoplasmic eosinophilic, and some cells are round or oval and epithelioid in shape (HEx400). (D) One case has slightly abundant tumor cells, and the mitotic phase is visible (about 1-2/10HPF)(HEx400). (E) Vascular endothelial cells CD34(+)(IHCx100). (F) Tumor cell vimentin(+)(IHCx100).
IJWH-15-427-g0001.jpg
PMC10040152_02_IJWH-15-427-g0001.jpg
f0001
The hypercellular areas alternated with hypocellular areas and abundant thin-walled small blood vessels were observed (Figure 1B). In the hypercellular areas, tumor cells, spindle-shaped and cytoplasmic eosinophilia, were distributed in bundles or patches around blood vessels, and some round or oval and epithelioid cells were observed (Figure 1C). The pathological findings also suggested that tumor cells were relatively abundant and mitosis was visible (approximately 1-2/10 HPF) (Figure 1D). On the suspicion of AMFB, the immunohistochemistry indicated the following results: ER (+), PR (+), Vimentin (+), CD34 (+), SMA (+), desmin (-), MSA (-), AE1/AE3 (-), s-100 (-), and Ki67 (+, <5%) (Figure 1E and F).
PMC10040152_03