PMC9841462_01
Figure 1. Bone marrow aspirate smear and multiparametric flow cytometry finding.
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Blasts were positive for CD19, CD10, cyCD79a, CD34 and human leucocyte antigen-D related (HLA-DR) while negative for myeloid markers (CD13, CD33, CD117, cytoplasmic myeloperoxidase (cyMPO) as well as lymphoid T markers (CD7, CD4, CD8, cyCD3) (Figure 1).  Moreover, a high proportion of blast cells showed a hand-mirror morphology characterized by a cytoplasmic tail extending out from one pole of the nucleus (Hand-mirror cells) (Fig.1).They were negative for MPO.