PMC8655981_01
Clinical course of unilateral cyanotic forelimb with suspected arterial thrombosis in a dog following thrombolytic therapy. (A) Cyanosis was confirmed from the proximal third of the right forelimb on the presentation day, and the skin color became normal over time (B-F). The right forelimb skin color on the following days: day 0 (A), day 1 (B), day 2 (C), day 4 (D), day 6 (E), and day 21 (F).
fvets-08-795928-g0001.jpg
PMC8655981_01_fvets-08-795928-g0001.jpg
F1
In addition, cyanosis was identified on the proximal third of the right forelimb (Figure 1A). The pain of the right forelimb almost disappeared, and the skin color was restored to normal (Figures 1B-E). Twenty-one days after rtPA administration (Figure 1F), the dog presented a continuing gait pattern of knuckling, and the D-dimer level was significantly reduced (372.44 ng/mL) compared to that in previous tests.
Gross findings of (A) petechiae of the oral mucosa (arrow) and (B) ecchymosis of the trunk in a dog following rtPA administration.
fvets-08-795928-g0002.jpg
PMC8655981_01_fvets-08-795928-g0002.jpg
F2
Subcutaneous bleeding on the back of the trunk and one spot hemorrhage of the oral mucosa were observed (Figure 2).