PMC10372341_01
A chest CT scan revealed a large round lesion, approximately 6 cm in diameter, in the lower lobe of the left lung, with a well-defined border and homogeneous density. Following the enhancement scan, the edge of the lesion showed obvious ring enhancement, and villous tissue protruding inward.
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A second chest CT scan showed an enlarged space occupying lesion in the lower lobe of the left lung ( Figure 1 ), which was diagnosed as an infected-pulmonary cyst.
HE staining: Figure (B) is a partial enlargement of figure (A). (B): Fibrinous-like material is present in the upper left corner, and neoplastic trophoblasts are present in the lower right corner, with large hyperchromatic nuclei and no villi, as well as strongly positive immunohistochemical staining of the tumor at 40x magnification: (C) beta-hCG; (D) CK 8/18; (E) Ki-67; and (F) HPL; and at 20x magnification: (G) CD10; (H) GATA-3. The pathological diagnosis was chorionic epithelial carcinoma of the left lower lobe of the lung, and the diameter of the lesion was approximately 10 cm. Most of the lesion was necrotic, and only a few tumor cells were visible.
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HE staining ( Figure 2 ) showed a small number of tumor cells.