PMC3024289_01
Appendix biopsy showing large, pleomorphic lymphocytes with irregular nuclear contours and large nucleoli. (400 X).
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PMC3024289_01_1752-1947-5-5-1.jpg
F1
Pathology of his appendix by immunostaining revealed anaplastic cells strongly positive for CD3, CD56 together with strong focal EBV-encoded RNA (EBER) staining (Figures 1, 2, 3 and 4).
Positive staining of lymphoid infiltrate for CD3 (400 X).
1752-1947-5-5-2.jpg
PMC3024289_01_1752-1947-5-5-2.jpg
F2
Pathology of his appendix by immunostaining revealed anaplastic cells strongly positive for CD3, CD56 together with strong focal EBV-encoded RNA (EBER) staining (Figures 1, 2, 3 and 4).
Gastric biopsy showing atypical lymphoid infiltrate (200 X).
1752-1947-5-5-3.jpg
PMC3024289_01_1752-1947-5-5-3.jpg
F3
Pathology of his appendix by immunostaining revealed anaplastic cells strongly positive for CD3, CD56 together with strong focal EBV-encoded RNA (EBER) staining (Figures 1, 2, 3 and 4).
Appendiceal infiltrate showing scattered Epstein Barr Virus-positive cells (100 X).
1752-1947-5-5-4.jpg
PMC3024289_01_1752-1947-5-5-4.jpg
F4
Pathology of his appendix by immunostaining revealed anaplastic cells strongly positive for CD3, CD56 together with strong focal EBV-encoded RNA (EBER) staining (Figures 1, 2, 3 and 4).
T cell receptor gene rearrangement by PCR analysis showing monoclonal spike.
1752-1947-5-5-5.jpg
PMC3024289_01_1752-1947-5-5-5.jpg
F5
TCK. The tissue was found to be positive for the T-cell receptor (TCR) by gamma gene rearrangement studies by PCR analysis (Figure 5).
EGD showing large ulcerated gastric nodule together with large nodules in the duodenum.
1752-1947-5-5-6.jpg
PMC3024289_01_1752-1947-5-5-6.jpg
F6
An esophagogastroduodenoscopy (EGD) was performed revealing multiple ulcerated nodular masses in the stomach and duodenum (Figures 6 and 7).
EGD showing multiple large gastric nodules with central ulceration.
1752-1947-5-5-7.jpg
PMC3024289_01_1752-1947-5-5-7.jpg
F7
An esophagogastroduodenoscopy (EGD) was performed revealing multiple ulcerated nodular masses in the stomach and duodenum (Figures 6 and 7).