PMC7341831_01
Histopathology of the lung. A. Numerous hyphae and fungal spores shown by H&E staining. Microscopic cavitation surrounded by numerous hypahes and fungal spores (40x). B. Well-defined Aspergillus head, allowing the visualization of phialides and conidia, with numerous fungal spores (PAS, 400x). C. Well-defined aspergillary structure showing conidiophore, aspergillary vesicle, phialides, and conidia, as well as several hyphae of regular diameter, some with septations and dichotomous branches (Gomori-Grocott, 400x). D. Bronchopneumonia with alveoli filled by neutrophils (H&E, 400x). E. Fibrin thrombi occluding a medium-sized artery (H&E, 400x) F. Squamous metaplasia in alveolar epithelial cells (H&E, 400x).
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PMC7341831_01_1678-9849-rsbmt-53-e20200401-gf1.jpg
f1
Microscopic visualization of the lung showed the presence of clearly defined Aspergillus structures, including hyphae and fungal spores, and a well-defined Aspergillus head with phialides, conidia, and spores, as well as bronchopneumonia, fibrin thrombi occluding an artery, and squamous metaplasia (Figure 1).