PMC3202142_01
Chest X-ray.
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fig1
The chest X-ray revealed absence of a thymus and showed bilateral areas of opacities (Figure 1).
Histologic appearance of spleen sections stained with hematoxylin and eosin (a) and with Ziehl-Neelsen (b) showing BCG infiltration (arrows).
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fig2
Spleen analysis revealed severe BCG infiltration (Figure 2), thus establishing the definitive diagnosis of disseminated BCG disease.
BCG vaccination site at the time of immune reconstitution (a) 5 months after transplantation and (b) 5.5 months after transplantation, showing skin ulceration with massive infiltration of BCG.
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fig3
During this phase of immunological reconstitution, signs of BCG infection augmented with prominent nodules at the BCG inoculation site (Figure 3), enlarged thoracic and abdominal lymph nodes, fever, leukocytosis, and massive elevation of C-reactive protein.