PMC9884631_01
Chest X-ray at the time of admission. Peripheral consolidation lesions noted
of the right lung.
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Chest X-ray showed peripheral consolidation lesions of the right side (Figure 1).
Chest CT-scan at the time of admission. Several consolidation patches and
some ground grass opacities were primarily observed in the right upper and
lower lobes, more severe than 5-day prior CT-scan.
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Several consolidation patches and some ground glass opacities were primarily observed in the right upper and lower lobes on the chest CT image (Figure 2).
PMC9884631_02
Chest CT-scan obtained 14 days after admission. Significant consolidation
lesions in the right upper and lower lobes compared to the most recent
images, which were more severe than 14-day prior CT-scan.
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The chest CT conducted 7 days later revealed more significant consolidation lesions in the right upper and lower lobes compared to the most recent images. (Figure 3).
PMC9884631_03
Right lower bronchial biopsy result 17 days after admission. Multiple degrees
of alveolar damage, a thick intraalveolar septum, fluid accumulation in
bronchial sacs, and fungal hyphae branching at 45  angles were identified in
the analyses. Alveolar gaps were entirely obliterated and infiltrated by
lymphoid and plasma cells. Immunohistochemistry study revealed CK7 (+) in
lung cells, TTF-1 (+) in lung cells, CD34 (+) in vascular cells, and GMS
(Grocott) (+) on fungal hyphae; consistent with organized pneumonia
subsequent to SARS-CoV-2 infection.
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In addition, there was multilayer pneumocyte hyperplasia (Figure 4).
Chest X-ray obtained 3 days after corticoid initiation.
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CRP of 12.8 mg/L, inflammation reaction also dropped dramatically. Chest X-ray obtained 3 days after corticoid initiation showed consolidation lesion of the right lung, which meant significantly reducing (Figure 5).
PMC9884631_04
Chest CT-scan obtained 12 days after cortioid re-initiation. Fibrosis and
mildly extended of right upper bronchial lobe. Consolidation lesions were
reduced remarkable compared to 19-day prior CT-scan.
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Obtaining a chest CT-scan 12 days after corticoid re-initiation and a chest X-ray 1 month following discharge likewise revealed excellent improvement (Figures 6 and 7, respectively).
Chest X-ray obtained 1 month after discharge.
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Obtaining a chest CT-scan 12 days after corticoid re-initiation and a chest X-ray 1 month following discharge likewise revealed excellent improvement (Figures 6 and 7, respectively).
PMC9884631_05