PMC3909845_01
Desmoplastic fibroma of clavicle in 28-year-old man.. A. Part of plain anteroposterior radiograph of right clavicle reveals well-defined non-sclerotic marginated geographic lesion on medial one-third of right clavicle, with pathologic fracture. B-D. Coronal (B) T1-weighted magnetic resonance image shows hypointense to isointense signal compared to adjacent muscle, and lesion also demonstrates hypointense to isointense signal on axial (C) T2-weighted image. Gadolinium enhanced T1-weighted coronal (D) image reveals heterogeneous enhancement of mass. Also, adjacent bone marrow and soft tissue along periosteum are enhanced. E. Microscopic examination shows bland fibroblasts in background of numerous thick and wavy collagen fibers without evidence of cellular pleomorhpism, changes in nuclear-cytoplasmic ratio or mitotic activity (H&E, x 200).
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F1
Initial work-up with plain radiograph demonstrated an oval shaped osteolytic lesion on the medial one-third of the right clavicle with pathologic fracture (Fig. 1A). Further evaluation with MRI was done after 10 days (Fig. 1B-D). Despite its bland appearance, the tumor showed multifocal soft tissue extension (Fig. 1E).