PMC4752071_01
Contrast-enhanced computed tomography reveals a 2.8 cm, well circumscribed, solid, hypoenhancing cortical lower pole mass in the right kidney with 100 Hounsfield Units (axial and coronal view).
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Contrast-enhanced computed tomography of the abdomen demonstrated a 2.8 cm, well circumscribed, solid, hypoenhancing cortical lower pole lesion in the right kidney with 100 Hounsfield Units (Figure 1).
Histological examination showing microscopic characteristics of juxtaglomerular tumor cells (Eosin and Hematoxylin): tumor cells with mild nuclear atypia, inconspicuous nucleoli and pale ill-defined cytoplasm; Immunohistochemical study negative for Chromogranin A, WT-1, and CD 31; positive for AML (areas), vimentin (focally), and CD 117 (focally).
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Histopathologic examination revealed a rare juxtaglomerular cell tumor known as reninoma (Figure 2) after minucious immunohistochemical analysis, which was negative for Cytokeratin 35BH11, EMA, CD 34, CD 56, S-100, Chromogranin A, HMB-45, WT-1, and CD 31; and positive for AML (areas), vimentin (focally), ACTIN HHF35 (rare cels), and CD 117 (focally).