PMC4900109_01
45-year-old woman with primary breast angiosarcoma. Mammogram with left craniocaudal (A) and mediolateral oblique (B) views.
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Since the patient recently had a screening mammogram with benign findings (Fig. 1), she underwent a breast sonogram.
45-year-old woman with primary breast angiosarcoma. MRI. Left sagittal views (A, B) demonstrate a smooth, lobulated, hypointense mass on precontrast, T1-weighted images (A); and hyperintense on fat-saturated postcontrast images (B). Circumferential edema surrounds the hyperintense mass on the axial STIR image (C). The mass demonstrated rapid rise to peak with washout (D, red).
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Due to persistence of the palpable abnormality, the patient underwent a contrast-enhanced breast MRI (Fig. 2).
45-year-old woman with primary breast angiosarcoma, intermediate and high grades. The presence of solid growth pattern, prominent endothelial tufting with papillary projections, and blood lakes (not shown) are diagnostic features (Hematoxylin and Eosin stain; 200X magnification).
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Intermediate- to high-grade areas consisted of solid growth or prominent endothelial tufting with papillary formations as well as blood lakes (Fig. 3).