PMC8068478_01
Axial (A) and coronal (B) CT scans of the abdomen showing abdominal ascites and dilated bowel loops due to obstruction from peritoneal carcinomatosis.
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CIS three months prior. Cross-sectional imaging revealed left hydronephrosis, abdominal ascites, bowel obstruction from peritoneal carcinomatosis (Figure 1A and B), and newly enlarged bilateral inguinal lymph nodes the largest measuring 2.6cm in size.
PET NaF showing focal abnormal uptake at (A) the left parietal-temporal skull and (B) the left 6th rib both suspicious for metastatic disease.
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PET/CT scan revealed lesions suspicious of metastatic spread involving the left parietal-temporal skull and 6th ribs (Figure 2A and B).
(A-F) Metastatic urothelial carcinoma to the (A) diaphragm (B) small bowel, (C) liver (H&E stain, original magnification 200x), (D) lung (original magnification 100x), (E) gallbladder (original magnification 40x), and (F) bone marrow (original magnification 200x).
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Autopsy revealed metastatic involvement of the diaphragm, small and large bowels, liver, lung, gall bladder, and bone marrow (Figure 3A-F).