PMC9894278_01
H and E (100x) showing compact hyper-cellular Antoni A areas and myxoid hypo-cellular Antoni B areas and the inset (400x)
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Computed tomography (CT) scan of the lung showed a right upper lobe mass of 2.5 x 1 cm with right-sided hilar lymphadenopathy [Figure 1].
PMC9894278_02
H and E (100x) showing spindle cell lesion with cellular palisading areas in the inset (400x)
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A 50-year-old man presented to the hospital with chronic cough and a mass lesion on chest X-ray [Figure 2].
H&E (100x) with the inset showing S-100 strong positivity (Case 5)
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X-ray showed a mass which was confirmed on chest CT as a well-defined smoothly enhancing lesion in the right apical lung abutting superior vena cava superiorly likely neurogenic in origin, for which magnetic resonance imaging (MRI) was advised [Figure 3b].
IHC (100x) showing vimentin negative, CD34 negative, and SMA negative
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H and E section showed proliferated elongated spindle-shaped tumour cells having a round to oval centrally placed nucleus with cellular palisading at places [Figure 4].
PMC9894278_03
X-ray: Chest X-ray (PA view) showing well-defined opacity in the right lower zone in the para-cardiac region silhouetting Rt. cardiac border (Case 2)
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On CT scan chest, a well-defined heterogeneously enlarged lesion was present in the apical segment of the upper lobe of the right lung, which suggested Pancoast tumour [Figure 5].
Case 2 Ct: two axial CECT images showing a) Homogeneously enhancing Rt para-cardiac lung mass (Case 2). b) Lung window showing a soft tissue density lung mass in the Rt. apical region (Case 4)
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On histopathologic examination of the biopsy, tumour composed of bland-looking spindle cells arranged in fascicles with peripheral palisading of nuclei was seen in a myxoid background [Figure 6].
PMC9894278_04
H&E (100x) with the inset showing S-100 strong positivity (Case 5)
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X-ray showed a mass which was confirmed on chest CT as a well-defined smoothly enhancing lesion in the right apical lung abutting superior vena cava superiorly likely neurogenic in origin, for which magnetic resonance imaging (MRI) was advised [Figure 3b].
PMC9894278_05
Axial CEMRI showing the left apical heterogeneously enhancing lung mass
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IHC showed S100 positivity [Figure 7].