PMC4986673_01
Hematoxylin and eosin (H&E) staining of a tumor section.. Notes: (A) x200; (B) x400.
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The pathology diagnosis was angiosarcoma (Figure 1A and B) with immunophenotype: AE1/AE3(-), CD31(1+), CD34(-), CK18(-), F8(-), Vim(3+), CK5&6(-), P63(-), EMA(-), GCDFP 15(-), and Ki-67 (20%).
Chest CT images showing metastases before (A-C) and after (D-F) treatment with apatinib.. Note: The arrowheads indicate the pulmonary metastases.. Abbreviation: CT, computed tomography.
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Following 1 month of therapy, multiple lung metastases (Figure 2A-C) were either significantly reduced in size (Figure 2D, as indicated by arrowheads) or disappeared (Figure 2E and F), and the recurrent tumors of the scalp also disappeared, which was considered to be a PR.