PMC6529841_01
(A) Computed tomography (CT) of the abdomen showing a large mass of 20 cm size (red arrow). (B) CT of the abdomen showing a large tumor of 24 cm* 18 cm*12 cm (red arrow).
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PMC6529841_02_fendo-10-00316-g0001.jpg
F1
CT abdomen revealed a 24 cm mass adjacent to the uterus (Figure 1).
(A) Plasma glucose trend in case 1. (B) Plasma glucose trend in case 2.
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PMC6529841_02_fendo-10-00316-g0002.jpg
F2
Hypoglycemia was persistent and necessitated the use of high concentration of dextrose (D) solution (up to D 70%) and multiple administration of rescue D 50% ampoules (Figure 2).
PMC6529841_02
(A) Computed tomography (CT) of the abdomen showing a large mass of 20 cm size (red arrow). (B) CT of the abdomen showing a large tumor of 24 cm* 18 cm*12 cm (red arrow).
fendo-10-00316-g0001.jpg
PMC6529841_02_fendo-10-00316-g0001.jpg
F1
CT abdomen revealed a 24 cm mass adjacent to the uterus (Figure 1).
(A) Plasma glucose trend in case 1. (B) Plasma glucose trend in case 2.
fendo-10-00316-g0002.jpg
PMC6529841_02_fendo-10-00316-g0002.jpg
F2
Hypoglycemia was persistent and necessitated the use of high concentration of dextrose (D) solution (up to D 70%) and multiple administration of rescue D 50% ampoules (Figure 2).
(A) Spindle cells with fibrillary eosinophilic cytoplasm forming whorls consistent with gastrointestinal stromal tumor (GIST). (B) Diffuse positive staining to CD 117. (C) Immunohistochemistry showing diffuse positive staining to IGF-2 monoclonal antibody (MA5-17096, Thermofisher scientific Inc.). (D) No positive staining seen on the control for IGF-2 antibody (MA5-17096, Thermofisher scientific Inc.).
fendo-10-00316-g0003.jpg
PMC6529841_02_fendo-10-00316-g0003.jpg
F3
Pathology confirmed the diagnosis of GIST of the small intestine which stained positively for IGF-2 (Figure 3).