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The edge of the tumor (hematoxylin eosin reaction). On the left side the pancreas, on the right side the tumor.
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The histopathological appearance (Fig. 1) pleaded for a well differentiated endocrine carcinoma.
Immunohistochemical reaction for chromogranin.
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The pathology report showed that the chromogranin A immunohistochemical reaction (Fig. 2) was positive and Ki-67 proliferation index (Fig. 3) was positive in 5-6% of tumor cells (nuclear expression), findings that were supporting the diagnosis of neuroendocrine tumor.