PMC5817358_01
Platelet Levels and Gabapentin Doses. Data graphed over the same time course, specified as (1) initial value, (2) after first titration of gabapentin, (3) after gabapentin discontinued, (4) after second titration of gabapentin (restarted due to efficacy and consideration that thrombocytopenia might be secondary to HIV-induced thrombocytopenia rather than medication), and (5) after gabapentin discontinued again.
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fig1
Gabapentin was titrated up to 1200 mg/day and was found to be effective for anxiety, but, within six days, the patient's platelet count dropped to 61k/uL (Figure 1), and gabapentin was discontinued while other medications remained the same. Gabapentin was discontinued again and, within two days, the platelet count increased back to 81k/uL (Figure 1).