PMC8213507_01
Computed tomography revealing bone metastasis (arrow). (a) C5, (b) L4, (c) S1, and (d) left acetabular cartilage.
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Computed tomography (CT) revealed a thyroid tumor and multiple vertebral bone metastases (C5, L4, S1, and left acetabular cartilage) (Figure 1).
Pathological diagnosis of poorly differentiated carcinoma derived from follicular thyroid carcinoma with minimal invasion; Victoria Blue hematoxylin and eosin staining, 200x.
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Pathological diagnosis was poorly differentiated carcinoma derived from follicular thyroid carcinoma with minimal invasion (Figure 2).
Iodine-131 scintigraphy after radioactive iodine therapy. No uptake was observed in the metastatic lesions.
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However, no uptake was observed in the metastatic lesions (Figure 3).
Magnetic resonance imaging revealing thickening of the right inferior rectus muscle (asterisk).
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One year after RAI, the patient presented with diplopia, and magnetic resonance imaging revealed a thickening of the right inferior rectus muscle (Figure 4).
Change of thyroglobulin (Tg) and thyroglobulin antibody (TgAb) levels (from thyroid-associated ophthalmopathy occurrence to improvement).
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However, Tg and TgAb gradually decreased with sorafenib and lenvatinib administration, and TAO was improved two years after occurrence (Figure 5).