PMC10017523_01
(A) Stained with acetic acid, thick vinegar white epithelium, and the accompanying abnormal blood vessels can be seen between 3 and 6 o'clock of the right cervix. (B) The nondominant left cervix was concealed by the side wall of the left vagina. After exposing, the left side cervix presented a mature appearance which was smaller than a normal cervix.
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After exposing, the left side cervix presented a mature appearance which was smaller than a normal cervix ( Figure 1 ).
The right cervical canal and the left cervical orifice can be seen in the MRI image at this plane.
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P53 (+, positive rate of 20%), Ki67 (approximately 30%); 2. (RIGHT ECC) the submitted tissue is a small blood clot; 3. (LEFT ECC) the submitted tissue is a little mucus; 4. (LEFT CDB) chronic inflammation at the left cervix. Pelvic magnetic resonance imaging (MRI) revealed two cervical canals and a 1.9cmx1.6cm mass inside the left cervix ( Figure 2 ).
(A) Hematoxylin and Eosin stain (x200): The tumor shows gastric type differentiation with abundant clear or pale, eosinophilic cytoplasm with atypical nucleus; (B-D) Immunohistochemical stains are focally positive for Muc-6 (B), P53 (D), and positive for P16 (C).
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Immunohistochemistry of the tumor cells were as follows: Muc-6 (+, focally), P16 (+, focally), P53 (20% medium intensity +), ER (+, focally), PR (-), CK7 (+++), CK20 (+, focally), Muc-2 (+, focally), Muc-5 (++), CDX-2 (+), SATB2 (-), Pax-8 (-), and the ki67 proliferative index was around 15% ( Figure 3 ).