PMC4437287_01
High resolution chest scans which show widespread bronchiectasis in the four quadrants (A); and in the cross sections at the level of the aortic arch (B), and the left ventricle (C).
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Since 2002 cylindrical and cystic bronchiectasis had been documented in all four quadrants (Fig. 1A), equally documented in the cross sections at the level of the aortic arch and the left ventricle (Fig. 1B y1C).
Quantification of T lymphocytes (CD4+/CD8+ and B lymphocytes (CD19+/CD20+) populations by flow cytometry in peripheral blood. Analysis of dot plot size and complexity (Forward and Side scattered) of total leukocytes (A), quantification of CD4+ T lymphocytes and CD8+ T lymphocytes (B), and total B lymphocytes quantification (C). Note the reversal of the CD4/CD8 ratio, 1:3 (instead of 2:1) and the percentage increase of 30% (6-19%) in B Lymphocytes.
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Evaluation of lymphocyte subpopulations in peripheral blood showed an absolute B lymphocyte count of 420 normal cells/microL (100-500) (Fig. 2C), accompanied by inversion of the lymphocyte T CD4+/CD8+ ratio, at the expense of a decrease in CD4+ T lymphocytes to 190 cells /L (300-1,400) (Fig. 2B).