PMC9132688_01
(a) A low-power view of the ileal biopsy specimen (hematoxylin and eosin stain; original magnification x40). (b) Amorphous eosinophilic deposits are apparent on the vessel wall (hematoxylin-eosin stain, original magnification x200). (c) Immunohistochemically, deposits show positive staining for beta2-microglobulin (original magnification x200).
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fig1
Histopathological examination of the specimen from ileal biopsy showed amorphous eosinophilic deposits on the vessel wall (Figures 1(a) and 1(b)). Immumohistochemically, deposits were positive for beta2m (Figure 1(c)).
A collection of whitish-yellow papules is evident on the ventral surface of the tongue tip.
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fig2
On oral examination, a collection of painless, relatively hard, rugged whitish-yellow papules was found on the ventral surface of the tongue tip (Figure 2).
(a) Amorphous extracellular eosinophilic deposits are shown in the subepithelial region (hematoxylin-eosin stain, original magnification x100). (b) Extracellular deposits show positive staining with direct fast scarlet (DFS) (original magnification x100). (c) Extracellular deposits show positive staining with potassium permanganate- (KMnO4-) DFS stain (original magnification x100). (d) Staining for beta2-microglobulin is also positive (original magnification x100).
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fig3
Histopathologically, the specimen showed amorphous eosinophilic extracellular deposits in the subepithelial region (Figure 3(a)). Extracellular deposits showed positive results from DFS staining, and also from potassium permanganate- (KMnO4-) DFS staining and beta2m staining (Figures 3(b)-3(d)).