PMC5588322_01
Axial T1 magnetic resonance imaging (without and with gadolinium injection) showed the nasal and palpebral (inferior) tumors (arrows) with strong contrast enhancement.
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F1
Magnetic resonance imaging showed a subcutaneous mass of the left nose pyramid associated with smaller nodules of the internal cantus and palpebral area (inferior; fig. 1).
a The tumor consisted of a spindle cell proliferation with Antoni A and B zones. HE stain. b Numerous intratumor vessels and macrophage aggregates were observed between tumor cells or subendothelially (arrows: b HE stain and inset CD68 immunohistochemistry, respectively). The tumor cells expressed S100 and WT1 proteins (immunohistochemistry: c and d, respectively). Intratumor CD4 and CD8 T lymphocytes were seen in similar proportions (immunohistochemistry: e and f, respectively). Original magnification x10 (a, b, e, f), x20 (c, d), x40 (inset in b).
mpp-0025-0096-g02.jpg
PMC5588322_01_mpp-0025-0096-g02.jpg
F2
The histological features (the specimens were analyzed entirely) were those of schwannoma (fig. 2).