PMC6899289_01
Baseline chest CT showing a large mass originating from the right thyroid lobe (a), with lung metastases (b), and hilar and mediastinal lymph nodes (c). (a), (c) images in mediastinal window. (b) image in lung window.
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There were multiple pathologically enlarged cervical, supraclavicular and mediastinal lymph nodes as well as multiple bilateral lung metastases (Figure 1).
Chest CT after 3 cycles of pembrolizumab showing marked regression of primary tumor (a), lung metastases and (b), lymph nodes (c).
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After only 2 cycles, the patient noticed a marked improvement of dysphagia and after 3 cycles, a near complete response was seen on CT (Figure 2).
Chest CT 6 months after start of pembrolizumab showing ongoing response.
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There were no signs of extra-cranial tumor progression (Figure 3).