PMC6584841_01
Intraoperative findings of Valproic Acid induced Acute Pancreatitis (AP).. Evidence of a: steatonecrosis foci on parietal peritoneum; b: peripancreatic fat; c: pancreatic necrosis at the head of the pancreas.
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Intraoperative findings included necrohemorragic intra- and retroperitoneal fluid, extending to omental bursa and periduodenal space, with segmental epiploic necrosis, multiple stheatonecrotic foci on the pancreatic cell, and superficial head, body, and tail pancreatic necrosis (Fig. 1), requiring negative pressure system (VAC Abthera ) placement in pancreatic cell.
Etiological diagnosis algorithm of acute pancreatitis.. AP: acute pancreatitis; CHOLANGIORMN; cholangioresonance; TG: triglycerides; ERCP: endoscopic retrograde cholangiopancreatography; Dx: diagnostic; LABS: laboratory tests; HIV: human immunodeficiency virus; HBV: hepatitis B virus; EBV: Epstein Barr virus; ANAS; antinuclear antibodies; ENAS: extractable nuclear antibodies; C3-C4: complement proteins.
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This lead our research group to design an etiologic diagnostic algorithm, according to the epidemiological frequencies in the light of actual evidence (Fig. 2).