PMC4831492_01
Extensive swelling, cutaneous erythema, blistering and gangrenous changes of the skin (arrows) over dorsum of left hand, noted 12 h after extravasation
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F1
Over next 12 h, there was progressive swelling, skin erythema, blistering and early cutaneous gangrenous changes were noted at the extravasation site [Figure 1].
Necrotic changes of the skin and soft tissues (arrow), ulceration and exposure of underlying muscles and tendons noticed 60 h after extravasation
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F2
Necrotic changes of skin and soft tissues [Figure 2] were noted 60 h after the extravasation and empiric antibiotic coverage with co-amoxiclav (1.2 g IV 8 hourly) and levofloxacin (500 mg IV once daily) was started.