PMC5671977_01
Timeline of diagnosis and treatment.
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F1
MRI showed regression of the leptomeningeal enhancement a month after starting therapy and cleared up at month 4 (Figure 1).
Spine MRI before and after 7 months of metronomic chemotherapy. MRI evidence of disseminated leptomeningeal tumor in pre-treatment T1-weighted gadolinium enhanced sagittal view (A) disappeared after 7 months of metronomic chemotherapy (B).
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F2
At last follow up, brain and spinal MRI is clear (Figure 2) and so is CSF examination.