PMC4719501_01
Pretreatment radiological images. (a) Computerized tomography scan and (b) intravenous urography showing thickening of the right lateral aspect of the urinary bladder wall (arrow)
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F1
Ultrasound, computerized tomography (CT), and intravenous urography showed diffuse thickening of the bladder wall [Figure 1a and b].
Pretreatment cystoscopy. A nonulcerated nodular bulge is seen on the right lateral wall of the bladder mucosa (arrow)
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F2
Cystoscopy showed a smooth nonulcerated nodular bulge in the right side of the bladder wall [Figure 2].
Histopathology images. (a and b) Intact but attenuated urothelium with diffuse replacement of subepithelium by lymphoma cells (H and E, x100 and x200). Lymphoma cells shows (c) CD45 positivity and (d) CD20 positivity on immunohistochemistry (x100)
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F3
CD45 and CD20 [Figure 3]. Cytokeratin, epithelial membrane antigen (EMA), CD3, CD5, CD10, and Bcl2 were negative.
Posttreatment images. (a) Computerized tomography scan and (b) cystoscopy showing completely unremarkable bladder wall and mucosa
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F4
Repeat CT scan, cystoscopy, and postchemotherapy showed completely normal bladder [Figure 4].