PMC5216153_01
The clinical course. The patient's respiratory function deteriorated with CO2 accumulation despite DP (MIP: maximal inspiratory pressure).
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Stimulation parameters were set at: frequency, 12 Hz; pulse width, 150 musec; and intensity, 17 mA (Fig. 1).
Pathology of the diaphragm. A: Severely atrophied diaphragm with 2 DP electrodes on each side. Several localized adhesions of electrodes are indicated (arrows; bar=10 mm), B: Hematoxylin and Eosin staining of the diaphragm (magnification 100x). Mild hyalinization was observed around the DP electrode track (T). A multinucleated giant cell was detected (arrow), however, the infiltration of mononuclear cells around the track was not observed.
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Several adhesions between the DP electrodes and diaphragm were observed adjacent to the tip of the DP electrodes (Fig. 2A). However, the infiltration of mononuclear cells around the tracks was not observed (Fig. 2B).