PMC9897325_01
Hematoxylin & eosin (H&E) stained sample (magnification x2) of the mass that was excised from the pharynx. The figure shows diffuse sheets of atypical, mostly monotonous, plasma cells with occasional binucleate forms. Only occasional mitoses are seen.
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FIG1
Upon admission, the surgical tissue biopsy from the pharyngeal mass showed diffuse sheets consisting of plasmacytoma plus multiple myeloma deposits (Figures 1, 2).
Hematoxylin & eosin (H&E) stained sample (magnification x20) of the mass that was excised from the pharynx. The figure shows diffuse sheets of atypical, mostly monotonous, plasma cells with occasional binucleate forms. Only occasional mitoses are seen.
cureus-0015-00000033358-i02.jpg
PMC9897325_01_cureus-0015-00000033358-i02.jpg
FIG2
Upon admission, the surgical tissue biopsy from the pharyngeal mass showed diffuse sheets consisting of plasmacytoma plus multiple myeloma deposits (Figures 1, 2).
Positive cells on CD38 stain of the mass that was excised from the pharynx
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FIG3
On immunohistochemistry, the lesional cells were positive for CD38 (Figure 3), CD79a (Figure 4), and CD138 (Figure 5), and were showing lambda light chain restriction (Figure 6).
Positive CD79a stain on the mass that was excised from the pharynx
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PMC9897325_01_cureus-0015-00000033358-i04.jpg
FIG4
On immunohistochemistry, the lesional cells were positive for CD38 (Figure 3), CD79a (Figure 4), and CD138 (Figure 5), and were showing lambda light chain restriction (Figure 6).
Positive CD138 stain on the mass that was excised from the pharynx
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PMC9897325_01_cureus-0015-00000033358-i05.jpg
FIG5
On immunohistochemistry, the lesional cells were positive for CD38 (Figure 3), CD79a (Figure 4), and CD138 (Figure 5), and were showing lambda light chain restriction (Figure 6).
Image showing some restriction on the light chain of the mass that was excised from the pharynx
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FIG6
On immunohistochemistry, the lesional cells were positive for CD38 (Figure 3), CD79a (Figure 4), and CD138 (Figure 5), and were showing lambda light chain restriction (Figure 6).
No staining on kappa of the mass that was excised from the pharynx was present
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FIG7
However, there was no staining on Kappa (Figure 7).
Positron emission tomography (PET) scan of the oropharynx showing increased uptake in the left oropharynx
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FIG8
After mass removal, the whole body positron emission tomography (PET) scan was notable for mildly increased uptake in the left oropharynx (Figure 8), which was nonspecific but residual tumor could not be excluded.