PMC10086349_01
A large cutaneous mast cell tumors (MCT) (photographed on July 18, 2013) is seen under the right nostril and invasion to the nasal planum, consistent with malignancy. (A) The tumor gradually resolved over several months after the patient's parent initiated the carbohydrate-free, calorie restricted ketogenic diet (B-D), as described in methods. The small bare patch on the lip below the tumor can serve as a reference point to assess the degree of the diet-linked tumor shrinkage. A facial image from October 2016 is also shown in the Supplementary material.
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F1
The tumor continued to grow on this diet invading local tissues and reaching a size of about 4 cm (Figure 1A). Two weeks prior to the July 2013 image shown in Figure 1A, the patient's diet was switched to a calorie restricted raw ketogenic diet. As no further diagnostic analysis was done on the tumor in 2013, it is not known if the grading of the tumor would have increased over the 2 years period from initial diagnosis in 2011 to that shown in Figure 1A and in the Supplementary material. The tumor gradually disappeared over a period of several months when the patient was switched to the raw calorie restricted ketogenic diet (Figures 1B-D).
Timeline of clinical course with dates of dietary treatments.
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F2
A timeline of the case is shown in Figure 2.