PMC3573451_01
Clinical photo showing swelling and erythema on the dorsum of the nose
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F1
The area was inflamed, erythematous and tender [Figure 1].
(a) Photomicrograph showing diffuse lymphomatous infiltrate destroying the hair follicles (H and E, x40); (b) Photomicrograph showing extensive areas of necrosis (H and E, x100); (c) Photomicrograph showing atypical lymphocytes admixed with histiocytes, plasma cells and eosinophils (H and E, x400)
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F2
The infiltrate was seen destroying the hair follicles [Figure 2a]. Extensive areas of necrosis were also seen [Figure 2b]. Plasma cells, histiocytes and eosinophils were present admixed with atypical lymphocytes [Figure 2c].
(a) IHC showing atypical lymphocytes positive for LCA (H and E, x100), (b) IHC showing atypical lymphocytes positive for CD56 (H and E, x100), (c) IHC showing atypical lymphocytes positive for CD3 (H and E, x100)
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F3
Immunohistochemistry was performed and the lymphomatous infiltrate was found to be positive for LCA [Figure 3a], CD56 [Figure 3b] and CD3 [Figure 3c].