PMC5312194_01
Irregular hyperpigmented lesion on the left buttock, with a diameter of 1
cm
abd-92-01-0124-gf01.jpg
PMC5312194_01_abd-92-01-0124-gf01.jpg
f1
Clinical examination revealed a 1 cm hyperpimented (half dark brown and half light brown) macule with relatively regular borders (Figure 1).
The dermoscopy of the lesion shows an amorphous light brown area adjacent to
a dark brown area containing irregularly distributed globules, streaks and
blackened gray parts
abd-92-01-0124-gf02.jpg
PMC5312194_01_abd-92-01-0124-gf02.jpg
f2
Dermoscopy showed an amorphous lightbrown areaadjacent to a dark brown area, containing irregularly distributed globules, streaks and grayished-black portions (Figure 2).
Pigmented Bowen's disease: loss of polarity, atypias in all layers of the
epidermis, mitoses, dyskeratosis and dyskaryosis. Presence of melanophages
and increased pigmentation of keratinocytes (Hematoxylin & eosin
x400)
abd-92-01-0124-gf03.jpg
PMC5312194_01_abd-92-01-0124-gf03.jpg
f3
An excisional showed loss of polarity, atypias in all layers of the epidermis, mitoses, dyskeratosis and dyskaryosis (Figure 3).
Fontana-Masson staining reveals prominent build-up of melanin in all the
layers of the epidermis and melanophages in the superficial dermis
(Hematoxylin & eosin x100)
abd-92-01-0124-gf04.jpg
PMC5312194_01_abd-92-01-0124-gf04.jpg
f4
The Fontana-Masson stain showed a heavy accumulation of melanin in the epidermis and melanophages in the upper dermis (Figure 4).