PMC4501461_01
Chest computed tomography (CT) scan revealed ground-glass opacities and interlobular septal thickening (A). Multiple ground-glass opacities and interlobular septal thickening on CT showed spontaneous regression six months after the discontinuation of methotrexate (B).
gr1.jpg
PMC4501461_01_gr1.jpg
fig1
Chest computed tomography (CT) showed multiple cysts with thin wall, bilateral multiple ground-glass opacities, multiple nodules, and interlobular septal thickening in the middle and lingular segments (Fig. 1A). Interestingly, the multiple ground-glass opacities and interlobular septal thickening that were observed on CT images underwent spontaneous regression six months after the discontinuation of MTX (Fig. 1B).
The cellular infiltrate is present along the alveolar septa and the interlobular septum and onto the pleura. Formation of lymphoid follicles is scant. The inset is a higher magnification showing predominantly small lymphoid cells in the infiltrate (A). The immunohistochemical study revealed aggregates of those cells showed restricted staining for immunoglobulin lambda light chains (B).
gr2.jpg
PMC4501461_01_gr2.jpg
fig2
Histopathological evaluation and immunohistochemistry led to the diagnosis of an extranodal marginal zone lymphoma of the MALT-type (Fig. 2).