PMC4856912_01
Medullary carcinoma (H + E): nests or chords of cells penetrating dense pink stroma ((a) x200). Tumor cells were round, relatively uniform with a punctuate chromatin ((b) x400).
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Microscopy revealed the histological features of medullary carcinoma, such as nests or chords of cells penetrating dense pink stroma with a lobular or trabecular growth pattern (Figure 1(a)). On higher power examination, the neoplastic cells were round, relatively uniform with a punctuate chromatin (Figure 1(b)).
On immunohistochemistry tumor cells were positive for calcitonin ((a) x200) and CEA ((b) x200).
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On immunohistochemistry tumor cells were positive for calcitonin (Figure 2(a)) and CEA (Figure 2(b)).
Patient with miosis and blepharoptosis one day after surgery (a). Restoration was achieved four weeks after operation (b).
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In the first postoperative day, the patient presented right blepharoptosis (Muller muscle) and miosis (stimuli were slower in the affected pupil) typical of Horner's syndrome (Figure 3(a)). Ptosis and miosis disappeared after four weeks (Figure 3(b)).