PMC5161795_01
(a) Muscle biopsy showing small fibers in the perifascicular portion of the biopsy (right side) with normal sized fibers in the central portion of the fascicle (left side). Perifascicular atrophy is pathognomonic for dermatomyositis. There are also blue discolored degeneration/regeneration fibers scattered throughout the biopsy. Paraffin embedded section, H&E,x175. (b) A distorted frozen section shows small round mononuclear inflammatory cells in the upper right quadrant of the picture. H&Ex175.
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F0001
Because of the refractoriness of therapy, a muscle biopsy was done which confirmed the clinical diagnosis of dermatomyositis (Fig. 1a and 1b).