PMC6263094_01
Radiological findings on admission. Chest X-ray showed bilateral bronchial wall thickening (A), and CT showed central bronchiectasis, high-attenuation mucoid impaction (arrow) (B), and centrilobular opacities and nodules (C).
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Chest X-ray showed bilateral bronchial wall thickening, and chest computed tomography (CT) revealed central bronchiectasis, mucoid impaction, and diffuse bronchial wall thickening (Fig. 1).
Bronchoscopy findings. Mucoid plugs were found in several bronchi.
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Bronchoscopy showed mucous plugs (Fig. 2), and Fig. 3A shows the mucus plugs aspirated by bronchial washing.
Radiological findings over the clinical course showed improvement (A: before mepolizumab, B: after mepolizumab).
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In January 2018, 94 weeks after starting omalizumab, it was switched to mepolizumab (100 mg/4 weeks), which kept her asthma in remission, led to the remission of her sinusitis and otitis media, and improved her radiological findings (Fig. 4).