PMC2938433_01
Granular cell tumor of the forth toe of the right foot.
DRP2010-184125.001.jpg
PMC2938433_01_DRP2010-184125.001.jpg
fig1
A 54-year-old patient, with no prior history of skin cancer, was examined in October 2008 with a yellowish, hyperkeratotic neoformation causing pain, affecting the forth toe of the right foot (Figure 1); no local or popliteal lymphadenopathy was noted.
Immediate postop: reconstruction of the forth digit with the dermal regeneration template (Integra).
DRP2010-184125.002.jpg
PMC2938433_01_DRP2010-184125.002.jpg
fig2
The toe was reconstructed with a dermal regeneration template made of cross-linked bovine collagen and chondroitin-6-sulfate (Figure 2) (Integra, Integra Life Sciences Corporation, Plainsboro, NJ).
Histologic examination (200X).
DRP2010-184125.003.jpg
PMC2938433_01_DRP2010-184125.003.jpg
fig3
The final histological examination confirmed that the neoformation presents the histological characters of granular cell tumor (Figure 3).
Postop at three weeks.
DRP2010-184125.004.jpg
PMC2938433_01_DRP2010-184125.004.jpg
fig4
Three weeks after surgery the silicone layer of the template was removed, and the toe healed with reepithelization in a month (Figure 4).
Clinical follow-up at one year.
DRP2010-184125.005.jpg
PMC2938433_01_DRP2010-184125.005.jpg
fig5
The clinical followups carried out 6 months and one year after the operation have shown no relapse of the disease and complete resolution of the pain (Figure 5).