PMC9674503_01
Enhanced CT scan of kidney lesion in arterial (A) and venous (B) phase. The white arrows point at kidney mass, which shows early and intense enhancement of the lesion, already in the arterial phase. The mass measures 68 x 64 x 80 mm, with the uneven density due to the presence of hypodense contextual areas (curved arrows) referable to necrotic phenomena.
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The one on the right kidney (Fig. 1) measured 7 cm and showed intense arterial enhancement.
Enhanced CT scan of liver lesion in arterial (A) and venous (B) phase. The lesion in the right hepatic lobe exhibits contrast graphic features like the renal lesion, that is, significant enhancement in arterial phase (white arrows in image A), washout in later phases, and inhomogeneous appearance due to the presence of hypodense contextual areas (curved arrows); it is not always easy to discern primary lesions from secondary lesions.
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The lesion on the VI-VII hepatic segments (Fig. 2) measured 5 cm and showed arterial enhancement with wash-out in portal phase.
Enhanced MRI scan with liver-specific contrast agent; (A) arterial phase shows intense peripheral enhancement (white arrow), and widespread wash-out (white arrowheads) in (B) venous phase. The hepatobiliary phase (C) shows homogeneous hypointense signal of the lesion (curved arrows), which shows high signal intensity (white star) in DWI sequences (D) with high b-value.
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Chest CT scan demonstrates multiple micronodular formations with peri-bronchial distribution to both lung fields (white arrows in pictures A-C); image D shows the lesions of the right lung at greater magnification. Histopathological analysis showed to be non-necrotizing granulomatous nodules of sarcoidosis.
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The CT scan reported multiple areas of thickening with a tendency for peri-bronchial distribution to both lung fields; no lymphadenopathies, no brain lesions (Fig. 4).
Histopathology images of HCC at 10x (A) and 20x (B-D) magnification. Images A and B show tumor cells with enlarged nuclei with high replicative activity (black arrows); images C and D exhibit a macro trabecular growth pattern (arrowheads); Grade III based on Edmondson Class.
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