PMC3274422_01
Progressive clearance of verrucae vulgaris following daily topical application of vitamin A. Appearance of warts prior to vitamin A treatment (Panel A) and at 70 days (Panel B), 16 weeks (Panel C) and 6 months (Panel D). Large arrow indicates large wart on knuckle requiring the longest time to resolve. Small arrows indicate smaller warts cleared by 16 weeks.
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F1
There was a large (approximately 9 mm in diameter; large arrow Figure 1A) common wart on the middle knuckle of the right hand as well as 23 smaller warts (1 mm to 4 mm) at the base of and behind the knuckle of the index finger (small arrows, Figure 1A). Most of the smaller warts had been replaced with normal skin by 70 days (Figure 1B). The largest wart on the middle knuckle of the right hand, although replaced by mostly normal tissue after 4 months of treatment (Figure 1C), required 6 months of vitamin A treatment to completely resolve (Figure 1D).