PMC8114315_01
Ultrasound of right kidney, which measures 10.4 x 4.3 x 4.4 cm. There is minor renal cortical thinning asymmetrically involving the mid-pole cortex. The cortex is mildly hyperechoic. No sonographic evidence of calculus or ureteral dilatation.
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A bilateral renal ultrasound demonstrated minor cortical thickening without evidence of perinephric fluid collection, hydronephrosis, or ureteral dilatation (Figure 1).
Renal biopsy specimen. Trichrome stain of the kidney biopsy revealing approximately 30% scarring (A). Hematoxylin and eosin stain showing collapsing glomeruli with associated increase in size of Bowman's space (B and C). Extravasation of fibrin into Bowman's can be appreciated (C). Jones Silver stain highlighting the basement membrane (D). Immunofluorescent staining shows linear deposits of immunoglobulin G in the basement membrane (E).
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Light microscopy of the renal specimen revealed glomerular crescent formation with associated fibrinoid necrosis of the tufts on a background of minimal (10% to 20%) interstitial fibrosis and early tubular atrophy (Figure 2).