PMC5518508_01
PMC5518508_02
Interface hepatitis: portal tract with inflammatory infiltrate which extends past the limiting plate into the surrounding parenchyma (20x magnification).
CRIM2017-3516234.001.jpg
PMC5518508_02_CRIM2017-3516234.001.jpg
fig1
The core liver biopsy showed portal tracts with moderate to severe mixed infiltrate of lymphocytes, plasma cells, and eosinophils, associated with severe grade 4 circumferential interface hepatitis (Figures 1 and 2).
Hepatocytes at the interface are surrounded by inflammatory cells, causing hepatocellular damage (40x magnification).
CRIM2017-3516234.002.jpg
PMC5518508_02_CRIM2017-3516234.002.jpg
fig2
The core liver biopsy showed portal tracts with moderate to severe mixed infiltrate of lymphocytes, plasma cells, and eosinophils, associated with severe grade 4 circumferential interface hepatitis (Figures 1 and 2).