PMC6251239_01
Sagittal fluid-attenuated inversion recovery image delineates corpus callosum hypogenesis. The rostrum, genu, and splenium are absent while remnant of the body seems as a short thin line. Note polymicrogyria in the frontal lobe.
JCIS-8-45-g002.jpg
PMC6251239_01_JCIS-8-45-g002.jpg
F1
Sagittal FLAIR images demonstrated corpus callosum hypogenesis [Figure 1]. T2-weighted images [Figure 2]. There were bilateral frontal parasagittal polymicrogyria [Figures 1, 3 and 4].
Corpus callosum is absent in this coronal T2-weighted section through thalami. Lateral ventricles are slit like and small in caliper. They are upturned (black arrow) and there are Probst bundles (arrowhead), secondary to callosal hypogenesis. Note bilateral periventricular nodular gray matter heterotopia (white arrows).
JCIS-8-45-g003.jpg
PMC6251239_01_JCIS-8-45-g003.jpg
F2
T2-weighted images [Figure 2]. There were bilateral frontal parasagittal polymicrogyria [Figures 1, 3 and 4]. Nodular gray matter heterotopia was present in periventricular regions [Figures 2-4].
Axial T1-weighted image shows bifrontal parasagittal polymicrogyria (black arrows) and bilateral periventricular nodular gray matter heterotopia (white arrows).
JCIS-8-45-g004.jpg
PMC6251239_01_JCIS-8-45-g004.jpg
F3
T2-weighted images [Figure 2]. There were bilateral frontal parasagittal polymicrogyria [Figures 1, 3 and 4]. Nodular gray matter heterotopia was present in periventricular regions [Figures 2-4].
Subsequent axial T2-weighted images clearly delineate bilateral periventricular gray matter heterotopia (white arrows). Note bifrontal parasagittal polymicrogyria (a and b).
JCIS-8-45-g005.jpg
PMC6251239_01_JCIS-8-45-g005.jpg
F4
T2-weighted images [Figure 2]. There were bilateral frontal parasagittal polymicrogyria [Figures 1, 3 and 4]. Nodular gray matter heterotopia was present in periventricular regions [Figures 2-4].
Axial T2-weighted image demonstrates abnormal cerebellar foliation and fissuration with loss of the normal architecture in the inferior aspect of the cerebellar hemispheres, consistent with cerebellar dysplasia.
JCIS-8-45-g006.jpg
PMC6251239_01_JCIS-8-45-g006.jpg
F5
In the inferior aspects of both cerebellar hemispheres, there were abnormal foliation and fissuration with loss of the normal architecture, consistent with cerebellar dysplasia [Figure 5].