PMC5404341_01
PET-CT demonstrating hypermetabolic activity in the stomach (left) and esophagus (right).
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F1
There was, however, significant abnormal fluorodeoxyglucose uptake in the esophagus and stomach, consistent with significantly increased metabolic activity (Figure 1).
EGD showing (A) mucosal edema and diffuse erythema, and (B) exudates with diffuse underlying erythema and gastric atrophy mucosal edema.
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F2
Similarly, the stomach had thick mucosal exudates with underlying erythema (Figure 2).
High-power view of the squamous esophagus showing (A) marked intraepithelial lymphocytic infiltrates with dyskeratotic keratinocytes (arrows), and (B) T lymphocyte infiltration confirmed with CD3+ immunohistochemical staining.
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F3
Biopsies of the squamous esophagus demonstrated marked intraepithelial lymphocytic infiltrate with scattered dyskeratotic keratinocytes (Figure 3). There was no morphologic evidence of Hodgkin's lymphoma in any of the submitted biopsies, and additional immunostains showed a predominance of CD3+ with only rare CD20+ lymphocytes, ruling out GI tract infiltration by the patient's Hodgkin's lymphoma and low-grade B-cell lymphoma, respectively (Figure 3).