PMC3617887_01
Clinical appearance of 2 siblings with Nagashima-type PPK. The pictures show bilateral reddish, palmoplantar, hyperkeratotic lesions with erythematous borders of the palms, soles, elbows, and knees(a, b, e, f elder sister; c, d younger sister).
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F1
A 9-year-old girl and her 6-year-old sister presented with bilateral reddish, palmoplantar, hyperkeratotic lesions with erythematous borders (fig. 1a-d). Only the elder sister exhibited the clinical manifestations on her elbows and knees (fig. 1e, f), and both patients showed no involvement of the hair, nails, or teeth.