PMC3919951_01
Axial and coronal views from computed tomography scan revealing the position of the tumor protruding into the bladder with an intact surface.
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This was confirmed by cystoscopy demonstrating a protruding tumor on the right wall of the bladder with normal mucosa, measuring 2.0x2.0 cm (Fig. 1A and B).
Histopathological evaluation of the paraganglioma. (A) Paraganglioma composed of dual cell populations arranged in a characteristic nested Zellballen pattern (H&E staining; magnification, x400). (B) Synaptophysin (immunohistochemical stain) confirmed neuroendocrine origin, compatible with paraganglioma (magnification, x400).
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On histopathological evaluation, the tumor cells were arranged in a nested pattern (Fig. 2A). The histopathological examination showed positive staining for NSE, Syn, CgA and CD56, sustentacular cells stained positive for S-100 and the Ki-67 staining revealed a proliferation index of <2%, compatible with paraganglioma (Fig. 2B).