PMC7876684_01
Abdomen CT scan before (A) and after (B) systemic chemotherapy with FOLFIRINOX. Red arrow: thickened mesenteric peritoneal surface (A) markedly reduced after treatment (B). Yellow asterisk: high volume ascites (A) disappeared after treatment (B).
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Histology of peritoneal biopsy infiltrated by pancreatic adenocarcinoma without significant histological regressive changes to chemotherapy (A). Peritoneal biopsy after PIPAC procedure showing marked regressive changes with fibrosis and rare scattered individual tumor cells (B) positive at immunostaining for BerEP4 (inset) (A and B: H&E, B inset: immunoperoxidase).
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