PMC4899879_01
37-year-old male with solitary fibrous tumor of the prostate. Axial T1-weighted image demonstrates large, isointense mass replacing entire prostate.
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The mass was diffusely hyperintense on T1-weighted images (Fig. 1) and mildly hyperintense on T2-weighted images, with few nonspecific hypointense foci on the T2-weighted images (Fig. 2).
37-year-old male with solitary fibrous tumor of the prostate. Coronal, breath-hold, 3D, T1-weighted, noncontrast (A), early arterial (B), and delayed (C) high-resolution isotropic volume examination (THRIVE) show gradual enhancement of this mass from periphery to center.
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On contrast administration, there was a gradual enhancement from the periphery to the center (Fig. 3).
37-year-old male with solitary fibrous tumor of the prostate. Hematoxylin-eosin stain with magnification of 40X (A) and 100X (B) shows spindle-cell proliferation with hypercellularity in some areas and hypocellularity in other areas. Neoplastic cells are separated by thick bands of collagen, demonstrating foci of keloid-like hyalinization. There is minimal nuclear atypia and mitotic activity. No necrosis or lymphovascular invasion is identified. These features, along with the typical immunohistochemistry, are characteristic of solitary fibrous tumor of the prostate.
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There were areas of neoplastic cells separated by thick bands of collagen, demonstrating foci of keloid-like hyalinization (Fig. 4).