PMC4881273_01
Visual examination of the anus: a solid mass of a thumb tip size with an uneven indented surface located mainly in the left side of the anus was observed.
cro-0009-0249-g01.jpg
PMC4881273_01_cro-0009-0249-g01.jpg
F1
We found a solid mass of a thumb tip size with an uneven indented surface, which was erosive and bled easily; the mass was located mainly on the left side of the anal canal (fig. 1).
Thoracic-abdominal CT scan before the start of chemotherapy: multiple metastatic lesions in the lung and liver were detected.
cro-0009-0249-g02.jpg
PMC4881273_01_cro-0009-0249-g02.jpg
F2
Before the start of chemotherapy, thoracic-abdominal CT scan was performed, which showed multiple metastatic lesions in the lung and liver, similar to those revealed by the initial examination (fig. 2).
Thoracic-abdominal CT scan after 22 courses of mFOLFOX6 + bevacizumab therapy: a significant reduction in the size of metastatic lesions in the lung and liver was observed.
cro-0009-0249-g03.jpg
PMC4881273_01_cro-0009-0249-g03.jpg
F3
A reduction in the size of the lung and liver metastases was observed already after 4 courses of mFOLFOX6 + bevacizumab therapy, and after 22 courses, CT scan showed maximum reduction in the metastatic lesions in both sites (fig. 3).