PMC7669357_01
Bilateral legs with pigmentary changes.
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fig1
A 58-year-old white woman presented to the clinic with a hyperpigmented bluish-grey rash over the bilateral lower extremities persistent for two days (Figure 1).
Low-power magnification shows widely dispersed dermal pigmentation and an epidermis with no significant pathologic changes (20x; hematoxylin and eosin staining).
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fig2
Skin biopsy revealed scattered deposits of brown-black pigment in dermal spindle cells and minimal inflammation, indicating pigmentary rash (Figure 2).
Intermediate magnification shows coarse cytoplasmic granular brown pigmentation within aggregates of macrophages surrounding eccrine structures in the dermis (100x; hematoxylin and eosin staining).
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fig3
High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).
Intermediate magnification shows coarse cytoplasmic granular brown pigmentation within aggregates of macrophages surrounding eccrine structures in the dermis (200x; hematoxylin and eosin staining).
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fig4
High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).
High-power magnification displays coarse brown pigmented cytoplasmic granules within the dermal macrophages (400x; hematoxylin and eosin staining).
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fig5
High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).