PMC9940950_01
EGD/colonoscopies performed on the patients revealed hypertrophic gastric mucosa ((a) case 1, pylorus), as well as erythema, vascular congestion, and surface nodularity ((b) case 2, antrum).
CRIGM2023-4073588.001.jpg
PMC9940950_02_CRIGM2023-4073588.001.jpg
fig1
The patient then underwent EGD and colonoscopy, which demonstrated mild reflux esophagitis, a sessile serrated adenoma of the cecum, a tubular adenoma of the sigmoid colon, as well as erythematous, congested, and nodular gastric mucosa (Figure 1(b)). Moreover, random biopsies of the stomach antrum and body showed moderate chronic active gastritis in addition to increased intraepithelial lymphocytes and focal thickening of subepithelial collagen bands, up to 10 mum (Figure 1(b)).
Hematoxylin and eosin staining of the patients' gastric biopsies demonstrates reactive lymphoid infiltrates and prominent bands of collagen within the lamina propria ((a) case 1; (b) case 2), 400x magnification. Masson's trichrome staining highlights the collagenous thickening >10 mum, 400x magnification.
CRIGM2023-4073588.002.jpg
PMC9940950_01_CRIGM2023-4073588.002.jpg
fig2
Moreover, the body biopsies showed patchy thickening of collagen bands up to 12 mum within the lamina propria, as well as entrapped capillaries and surface epithelial disruption (Figure 2(a)).
PMC9940950_02
EGD/colonoscopies performed on the patients revealed hypertrophic gastric mucosa ((a) case 1, pylorus), as well as erythema, vascular congestion, and surface nodularity ((b) case 2, antrum).
CRIGM2023-4073588.001.jpg
PMC9940950_02_CRIGM2023-4073588.001.jpg
fig1
The patient then underwent EGD and colonoscopy, which demonstrated mild reflux esophagitis, a sessile serrated adenoma of the cecum, a tubular adenoma of the sigmoid colon, as well as erythematous, congested, and nodular gastric mucosa (Figure 1(b)). Moreover, random biopsies of the stomach antrum and body showed moderate chronic active gastritis in addition to increased intraepithelial lymphocytes and focal thickening of subepithelial collagen bands, up to 10 mum (Figure 1(b)).