PMC5438003_01
Kidney biopsy showing a glomerulus with cellular crescent formation (H & E stain; 400x).
CNCS-5-009-01.jpg
PMC5438003_01_CNCS-5-009-01.jpg
Figure1
Three glomeruli showed cellular crescent formation with epithelial cells and admixed inflammatory cells with scanty fibrin (Figure 1).
Kidney biopsy showing interstitial infiltrate of atypical lymphocytes (H & E stain; 100x).
CNCS-5-009-02.jpg
PMC5438003_01_CNCS-5-009-02.jpg
Figure2
There were patchy dense monotonous lymphocytic aggregates and many separate areas with mixed inflammation including frequent plasma cells, occasional eosinophils, and no neutrophils (Figure 2).
Kidney biopsy showing atypical lymphocytes in interstitium (A: H & E stain; 100x). Immunohistochemistry markers were positive for CD20 (B: 100x) and cyclin D1 (D: 100x), and negative for CD5 (C: 100x).
CNCS-5-009-03.jpg
PMC5438003_01_CNCS-5-009-03.jpg
Figure3
The lymphoid aggregates consisted of atypical mature lymphoid cells with irregular nuclear contours that were predominantly B-cells, positive for CD20 and cyclin D1, negative for CD3, CD5, and CD 10 (Figure 3).