PMC5465677_01
TAS-102 regimen. a Regular regimen. b Modified regimen.
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TAS-102 (35 mg/m2) was administered as a third-line treatment twice daily, after breakfast and dinner, for 5 days a week with 2 days of rest for 2 weeks, followed by a 14-day rest period (Fig. 1a). TAS-102 (35 mg/m2) was administered twice daily, after breakfast and dinner, for 5 days a week with 9 days of rest for 2 weeks (Fig. 1b).