PMC5863397_01
Clinical picture of the lesion
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F1
A 52-year-old female patient reported with a chief complaint of an enlarging but painless, gingival growth in relation to the lower front tooth region [Figure 1].
Surgically excised lesion
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F2
The lesion [Figure 2] was surgically excised with electrosurgical unit to minimize bleeding and postoperative discomfort [Figure 3] and subjected to histopathological examination.
Surgical site after removal of granuloma
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F3
The lesion [Figure 2] was surgically excised with electrosurgical unit to minimize bleeding and postoperative discomfort [Figure 3] and subjected to histopathological examination.
Vestibuloplasty of shallow sulcus
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F4
Vestibuloplasty was also performed to correct inadequate vestibular depth [Figure 4].
Histopathological picture showing numerous plasma cells in cytoma
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F5
Histopathological examination revealed a dense fibrovascular connective tissue with sheets of mixed inflammatory cell infiltrates comprising predominantly of plasma cells and few lymphocytes with an overlying parakeratinized stratified squamous epithelium with anastomosing rete pegs [Figures 5 and 6].
Magnified view of connective tissue stroma
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F6
Histopathological examination revealed a dense fibrovascular connective tissue with sheets of mixed inflammatory cell infiltrates comprising predominantly of plasma cells and few lymphocytes with an overlying parakeratinized stratified squamous epithelium with anastomosing rete pegs [Figures 5 and 6].
Immunohistochemical examination with kappa chain immunoglobulin markers
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F7
Immunohistochemical examination revealed kappa and lambda light chain immunoglobulin markers [Figures 7 and 8] which are used to differentiate reactive from benign and malignant lesions as was confirmed in our case, with a positive reaction revealing the lesion to be reactive rather than being benign or, malignant in nature.
Immunohistochemical examination revealing lambda chain immunoglobulin markers
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F8
Immunohistochemical examination revealed kappa and lambda light chain immunoglobulin markers [Figures 7 and 8] which are used to differentiate reactive from benign and malignant lesions as was confirmed in our case, with a positive reaction revealing the lesion to be reactive rather than being benign or, malignant in nature.
Follow-up examination revealing no reoccurrence of lesion
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F9
The patient was re-called after every 3 months [Figure 9] for 1 year for a follow-up.