PMC4857330_01
Showing the hazy appearance of the leptomeninges.
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At examination of the central nervous system (CNS), the brain weighed 1150 g with hazy leptomeninges (Figure 1).
Giemsa-stained touch preparation of the brain showing numerous cryptococcal organisms with little inflammatory response (400x).
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This showed numerous cryptococci (Figure 2).
Grocott-stained histological section of mesenteric lymph node showing numerous cryptococcal organisms with no inflammatory response (400x).
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The histological sections of the brain, mesenteric lymph node and ovarian nodule showed infiltration of their stroma by Periodic acid-Schiff (PAS) and Grocott positive fungi, consistent with cryptococcus infection (Figure 3).