PMC4237194_01
Pathology change of transbronchial lung biopsy (hematoxylin and eosin staining, A x 40; B x 200) showed fibrous tissue hyperplasia, inflammatory cell infiltration and histiocytic reaction in alveolar space. Chronic inflammatory cell infiltration and foamy phagocytes groups in small wall-thickened bronchioles and interstitial lung.
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The pathology change of transbronchial lung biopsy showed respiratory bronchiolitis (Fig. 1).
Electron microscopy of nasal mucosa showed cilia with the absence of both outer and inner dynein arms of the microtubules (transmission electron microscopy, 3 200 000).
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Then the absence of both outer and inner dynein arms of the microtubules was found by examination of the nasal mucosal biopsy specimen under transmission electron microscopy (Fig. 2).
Computed tomography (CT) images of the chest. (A) High-resolution computed tomography (HRCT) shows bronchiectasis and bronchiolitis, ring-shaped or ductal opacities in upper, middle and lower lungs, some of which are accompanied by small nodules. (B) Bronchiectasis involved in right middle lobe.
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Bronchiectasis mainly involved in the right middle lobe (Fig. 3).
Computed tomography (CT) images of the sinuses showed chronic maxillary sinusitis and (B) ethmoid sinusitis.
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Paranasal sinus CT showed chronic maxillary sinusitis and ethmoid sinusitis (Fig. 4).
High-resolution computed tomography (HRCT) images after 20 days of azithromycin therapy. (A) Nodular shadows were obviously attenuated, (B) but bronchiectasis did not change.
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Chest CT showed that nodular shadows were mildly attenuated after 2 months of azithromycin therapy, but bronchiectasis was not improved (Fig. 5).