PMC6849494_01
Time course of hormone level profile under resting and fasting conditions before and after 10 mg of estradiol valerate injection. White circle, estradiol; pink circle, cortisol; blue circle, ACTH.
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F1
As shown in Table 1 and Figure 1, estradiol level in this subject was not detected at all before estradiol valerate injection (0 pg/mL), but it was markedly elevated 7 days after the injection (276 pg/mL) and was not detected again at all 18 days later (0 pg/mL). ACTH and cortisol levels in this subject were 51.5 pg/mL and 32.4 mug/dL, respectively, before estradiol valerate injection. ACTH and cortisol levels were moderately decreased 7 days after estradiol valerate injection (28.3 pg/mL and 28.3 mug/dL, respectively), and, interestingly, both of them were markedly elevated 18 days after such treatment (ACTH, 84.5 pg/mL; cortisol, 38.9 mug/dL) (Figure 1).