PMC9938939_01
Histopathology report of renal biopsy (light microscopy).. The image shows the following: (1) glomerulus - glomeruli appeared enlarged and diffuse thickening of capillaries which showed membrane texture alterations and intramembranous mottling discernible in methenamine stained sections, no evidence of nodule formation, intracapillary thrombi and crescent formation. (2) Tubules - tubular atrophy and interstitial fibrosis in 10-12% of sampled cortex. (3) Arteries - mild medial thickness and arterioles revealed focal hyalinosis lesions. (4) Immunofluorescence - IgG- 3+, IgA, IgM and C1q Negative, Kappa and lambda- 3+, staining for PLA2R, THSD7A, NELL-1, EXT-1 and Sema 3b-negative.. Here, the green arrow shows thickened capillary wall and the blue arrow shows mesangial hypercellularity.
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FIG1
Renal biopsy findings are shown in Figure 1.