PMC10405981_01
Histopathology slide of adenocarcinoma with thyroid transcription factor-1 positive stain
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F1
Histopathology of the lesion was significant for adenocarcinoma grade III, thyroid transcription factor-1 positive [Figure 1].
Staging positron emission tomography-computed tomography scan showing a hypermetabolic left lower lobe lung mass with mediastinal and left level IV cervical lymphadenopathy
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F2
A positron emission tomography-computed tomography (PET-CT) scan revealed a highly active mass in the lower left lobe of the lung, accompanied by lymph node enlargement in the mediastinum and left level IV cervical region [Figure 2].
Radiotherapy plan for primary lung mass showing target volume coverage and dose volume histogram demonstrating planning volume radiation coverage doses to organs at risk
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F3
Followed by concurrent chemoradiation therapy using 55 gray units in 20 fractions [Figure 3] with cisplatin 100 mg/m2 on Day 1 and vinorelbine 50 mg/m2 on Day 1, 8 and 15.
Histopathology slide of metastatic lesion showing adenocarcinoma from primary lung cancer showing epithelial growth factor receptor mutation and anaplastic lymphoma kinase rearrangement not detected
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F4
Histopathology showed metastatic adenocarcinoma from the primary lesion with EGFR mutated at exon 21 and anaplastic lymphoma kinase rearrangement not detected [Figure 4].
Positron emission tomography-computed tomography scan showing hypermetabolic soft tissue mass in paraduodenal/peripancreatic area inseparable from uncinated process of pancreas
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F5
PET-CT showed hypermetabolic activity in the mass [Figure 5].
Coronal and axial sections of computed tomography scan post 6 months of erlotinib treatment showing complete resolution of pancreatic mass
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F6
After 6 months, the CT scan revealed disease remission [Figure 6].