PMC6736565_01
(A) Computed Tomography scan showing a 3 cm heterogeneous right adrenal mass of undetermined significance. (B) Strong Meta-iodobenzylguanidine (MIBG) uptake of the 2 x 2 x 3 cm right adrenal mass with no evidence of distant metastasis.
fendo-10-00546-g0001.jpg
PMC6736565_01_fendo-10-00546-g0001.jpg
F1
Patient was worked up for severe postoperative hypertension with a computed tomography (CT) scan which revealed a small right adrenal mass measured at 31 mm (Figure 1).
(A) More typical Zellballen's architecture with small tumor nests and very focal tumor cell spindling (Hematoxylin and eosin staining, 100 x). (B) Large tumor nests were also present (Hematoxylin and eosin staining, 100 x). (C) Chromogranine A immunostaining showing strong granular cytoplasmic positivity in the tumor cells (Chromogranine A staining, 200 x).
fendo-10-00546-g0002.jpg
PMC6736565_01_fendo-10-00546-g0002.jpg
F2
PHEO was confirmed by histology post-operatively (Figure 2). PHEO of the Adrenal gland Scaled Score (PASS) was 4, and the ki67 proliferation index was less than one percent.