PMC7803178_01
Multiple yellow-brown papules in the trunk.
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fig1
A dermatological examination revealed multiple papules between 3 and 5 millimeters in size, yellow-brown in color, distributed mainly in the trunk (Figure 1).
Mixed proliferation with elongated cells and multinucleated histiocytic-like cells of large eosinophilic cytoplasms with mild lymphocyte response (H-E x20).
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No significant atypia, mitosis, or necrosis was observed (Figure 2).
Positivity for histiocytic markers CD 68 (x10).
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fig3
The immunohistochemical study showed positivity for histiocytic markers CD 68 (Figure 3), vimentin (Figure 4), and alpha1 antitrypsin (Figure 5) and negativity for S-100, CD1a, factor XIIIa, and cytokeratins.
Positivity for vimentin (x10).
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fig4
The immunohistochemical study showed positivity for histiocytic markers CD 68 (Figure 3), vimentin (Figure 4), and alpha1 antitrypsin (Figure 5) and negativity for S-100, CD1a, factor XIIIa, and cytokeratins.
Positivity for alpha1 antitrypsin (x20).
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fig5
The immunohistochemical study showed positivity for histiocytic markers CD 68 (Figure 3), vimentin (Figure 4), and alpha1 antitrypsin (Figure 5) and negativity for S-100, CD1a, factor XIIIa, and cytokeratins.