PMC4336428_01
(A) Nests of tumour cells surrounded by desmoplastic stroma (magnification: 100x). (B) Cells with hyperchromic nuclei and scant cytoplasm (magnification: 400x). (C) Immunohistochemical stain positive for cytokeratin (CAM 5.2). (D) Immunohistochemical stain positive for desmin, with immunoreactivity present in a typical perinuclear dot-like Golgi pattern (large arrow).
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PMC4336428_01_gr1.jpg
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The diagnosis of DSRCT was made on the basis of the tumour morphology showing nests of tumour cells with hyperchromic nuclei and scant cytoplasm surrounded by desmoplastic stroma, and positive immunohistochemistry staining for desmin and cytokeratin (Fig. 1).
PMC4336428_02
PMC4336428_03