PMC549541_01
CT-Scan showed large heterogeneous mass of 13 x 10 cm size extending from the tail of pancreas to anterior prararenal space, lesser sac to gastrosplenic ligament enveloping the posterior aspect of fundus, body and greater curvature.
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F1
Ultrasonogram and CT-scan of the abdomen showed large heterogeneous mass of 13 x 10 cm extending from the tail of pancreas to anterior pararenal space, lesser sac to gastrosplenic ligament enveloping the posterior aspect of fundus, body and greater curvature (Figure 1).
Upper endoscopy picture shows opening in the posterior part of the corpus with edematous margin with dissemination of serous fluid and necrotic material in to the stomach.
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F2
Upper endoscopy showed large bulge in fundus and corpus of the stomach posteriorly with an opening in the posterior part of the corpus with edematous margin with dissemination of serous fluid and necrotic material in to the stomach (Figure 2).
Photomicrograph showing upper endoscopy biopsy specimen of gastric GIST showing multiple spindle cells with eosinophilic cytoplasm and ovoid to elongated nuclei
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F3
Biopsy taken from the edge of the opening showed bundles of spindle cells with elongated nuclei and tumor cells (Figure 3) and was strongly positive for CD117 immunohistochemical examination, diagnostic of gastrointestinal stromal tumor (Figure 4).
Photomicrograph of biopsy specimen with immunohistochemical staining for CD117
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F4
Biopsy taken from the edge of the opening showed bundles of spindle cells with elongated nuclei and tumor cells (Figure 3) and was strongly positive for CD117 immunohistochemical examination, diagnostic of gastrointestinal stromal tumor (Figure 4).