PMC8406023_01
Chest CT showing the condensation in the left upper lobe (red arrows). The bilateral ground glass opacities are not present on this section. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
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A lung CT scan was performed and showed bilateral apical ground-glass opacities associated to an atypical condensation in the left upper lobe apical segment (Fig. 1).
Histological section showing foci of pneumonia with many eosinophilic polynuclear cells (small arrow). Some alveolar ducts and alveoli are the site of endoluminal obstruction by fibrous granulation tissue consisting of inflammatory cells, fibroblasts, and connective tissue (big arrow). Magnification x400. Haematoxylin and eosin stain.
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Pathologic examination revealed the presence of foci of pneumonia with numerous eosinophilic polynuclear cells (Fig. 2).
Aspergillus niger growing on Sabouraud dextrose agar. Aspergillus niger is the only pathogenic Aspergillus whose head is radiated, biserial and black at maturity.
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However, a few days later, microbiology culture of the lung sample revealed black colonies with a granular appearance whose microscopic characteristics were reminiscent of Aspergillus niger (Fig. 3) leading us to consider the diagnosis of IPA.