PMC8293276_01
The treatment course of this case. ABVD, doxorubicin + bleomycin + vinblastine + dacarbazine; AE, adverse event; ASCT, autologous stem cell transplantation; BEAM, carmustine + etoposide + cytarabine + melphalan; CR, complete remission; HL, Hodgkin's lymphoma; GDP, gemcitabine + cisplatin + dexamethasone; mAb, monoclonal antibody; PD-1, programmed death-1; PD-L1, programmed death-ligand 1; PR, partial remission.
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F1
ABVD, the patient consented to receive PET/CT, and it showed CR. After continuing four cycles of ABVD regimen treatment (eight cycles of ABVD in total), the patient was followed by regular clinic follow-up (Figure 1).
PET/CT results of this case at different time points. (A) The PET/CT image when diagnosed. (B) A PET/CT examination after the fourth cycle of ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) showed complete remission (CR). (C) After programmed death-ligand 1 (PD-L1) monoclonal antibody (mAb) treatment, there were still multiple swollen lymph nodes in the PET/CT results, and new lesions were found in the pelvic cavity behind the peritoneum. (D) After two doses of programmed death-1 (PD-1) mAb treatment, PET/CT examination showed that the size of the retroperitoneal and pelvic lymph nodes was smaller, but new lesions occurred in the left clavicular lymph nodes. (E) After autologous stem cell transplantation (ASCT), this patient reached CR.
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F2
PLT 30 x109/L. PET/CT examination in August 2020 indicated that the patient achieved CR (Figure 2).