PMC4040034_01
Bone window axial CT images and coronal section of MRI show a bone defect located in the right posterior parietal region with skin bulging
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F1
Cranial computerized tomography (CT) scans showed a cranial bony defect in his right parietal bone [Figure 1].
Axial T1-weighted MRI with gadolinium enhancement reveals a mass lesion with irregular borders with heterogeneous contrast enhancement extending posterior and superior towards the temporoparietal structures accompanied by a non-enhancing cystic component
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F2
Magnetic resonance imaging (MRI) showed that the tumor was characterized by a cystic mass with a central homogeneous solid component enhancing with gadolinium attached to the dura, leading to a large effect on the ventricles in the temporoparietal region [Figure 2].
Tumor having a nodular pattern involving cerebral cortex and subcortex (H&E, x100)
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F3
The conventional histochemical stains Massontrichome (MTC) and Gomori'sreticulin stain were used to stain interstitial collagen fibers and reticulin fibers, respectively [Figure 3].
Diffuse interstitial reticulin fibers (Gomori'sreticulin, x200)
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F4
Randomly distributed intermingled GFAP reacting astrocytes in tumor are seen. (Streptavidin-biotin complement, GFAP, x200)
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F5
Scattered synaptophysin reacting ganglion cells are a major component of tumor. (Streptavidin-biotin complement, synaptophysin, x200)
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F6
MIB-1 index is 2% (Streptavidin-biotin complement, anti-Ki-67 [MIB-1], x200)
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F7
NFP and progesterone. Nearly 2% of tumor cells were labeled with Ki-67/MIB-1 [Figure 7], and approximately 1/3-2/3 of cells showed moderate nuclear staining for p53.