PMC5414486_01
Macroscopic appearance of a cross-sectioned uterus filled with a polypoid papillary mass, extending into the uterine cervix.
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Grossly, the uterine corpus, including both cornua, was filled with a polypoid papillary mass, measuring 11, 5 x 5, 5 cm, extending into the uterine cervix (Figure 1).
Microscopic appearance of endometrioid carcinoma with foci of squamous differentiation.
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Histologically, the tumor of the uterine corpus was a superficially invasive, moderately differentiated, tubulopapillary adenocarcinoma of the endometrium, of endometrioid type with multiple foci of squamous differentiation (Figures 2(a)-2(c)).
Immunostain: positive expression of p53 in endometrial carcinoma.
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Immunohistochemically, there was positive expression of hormone receptors and p53 (Figure 3).
H&E stain: superficial invasion of the uterine cervix by the endometrial carcinoma.
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The tumor was extending superficially to the uterine cervix (Figure 4).
H&E stain: microscopic appearances of multiple keratin granulomas, composed of ghost squamous cells surrounded by foreign body giant cells, found on the serosal surface of bilateral ovaries, fallopian tubes, the appendix, and omentum.
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In addition, on the serosal surface of bilateral ovaries, fallopian tubes, and the appendix, multiple microscopic granulomas were found, composed of amorphous irregularly laminated eosinophilic deposits of keratin, associated with ghost squamous cells and surrounded by foreign body giant cells (Figures 5(a)-5(c)).
H&E stain: degenerate squamous cells found in superficial areas of the uterine tumor.
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In retrospect, similar degenerate squamous cells were found in extensive, mainly superficial areas of the uterine tumor (Figure 6) as well as filling and distending the lumen of the fallopian tubes, bilaterally (Figures 7(a)-7(c)).
H&E stain: similar to Figure 6, degenerate squamous cells are filling and distending the lumen of the fallopian tubes (in various magnifications).
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In retrospect, similar degenerate squamous cells were found in extensive, mainly superficial areas of the uterine tumor (Figure 6) as well as filling and distending the lumen of the fallopian tubes, bilaterally (Figures 7(a)-7(c)).