PMC4917943_01
C-reactive protein CRP and white blood cell WBC trends from time of acute admission to hospital
40164_2016_45_Fig1_HTML.jpg
PMC4917943_01_40164_2016_45_Fig1_HTML.jpg
Fig1
The patients condition deteriorated over the course of 9 days with no evidence of a response to broad spectrum antibiotic therapy (including: Vancomycin; Ciprofloxacin; Tazocin, and; Meropenem) (Fig. 1) and persistently worsening SIRS and episodic hypotension without objective evidence of an infective source.
Macro- and microscopic tumour appearance. a Macroscopic image of excised breath tissue with section through tumour (white arrow). Microscopic images demonstrating: b tumour cells and lymphovascular invasion of the superficial epidermis; c high magnification image of tumour cells, and; d tumour involvement of the deep excision margin (black arrow)
40164_2016_45_Fig2_HTML.jpg
PMC4917943_01_40164_2016_45_Fig2_HTML.jpg
Fig2
At the time of surgery a 180 x 135 x 100 mm (821 g) diffusely oedematous, friable and haemorrhagic tissue mass was excised (Fig. 2). Histology of the resected specimen confirmed grade III pleomorphic carcinoma (>100 mm) with adjacent high grade ductal carcinoma in situ, lymphovascular invasion and extracapsular spread and significant necrosis (pT4,N1a,Mx; oestrogen/progesterone/HER-2 receptor negative, E-cadherin/cytokeratin-7/p53/p63 positive) (Fig. 2).