PMC8281915_01
Clinical evolution of the patient with radiation recall dermatitis. A. Hyperemic breast with serosanguinolent secretion seen one year after breast cancer treatment. B. Aspect of the breast after surgical debridement. C. Supportive treatment with papain and SAF-gel. D. Aspect of breast healing process between hyperbaric therapy sessions.
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She was then referred back to the mastologist (Fig. 1A). The patient was treated with repeated surgical debridements (Fig. 1B) associated with papain and SAF-gels (Fig. 1C) as recommended by the plastic surgery team. The patient was also referred for treatment with a hyperbaric chamber (Fig. 1D), and underwent 20 sessions.
Histopathological evaluation of the patient with radiation recall dermatitis. A. Hematoxylin-eosin stain with 40 x magnification showing intense neutrophilic exudate throughout the epidermis and dermis. B. Hematoxylin-eosin stain with 100 x magnification showing ulcerated epidermis with foci of parakeratosis and acanthosis, liquefactive and atypical reactions of the basal layer. In the dermis, fibrosis and elastosis are noted, with intense fibrinoid exudate and vascular thickening with extravasation of red blood cells
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The histopathological evaluation indicated acute erosive dermatitis, with vascular alterations suggestive of radiotherapy effects and absence of neoplasia (Fig. 2A and 2B).