PMC6735305_01
CSF fluid with numerous large B lymphoid cell not normally seen in normal CSF. (a) Tumor cell has multilobed nuclei which predominate. (b) Tumor cell has centrally located nucleolus and an appreciable amount of basophilic cytoplasm. (c and d). Immunoblasts with plasmacytoid differentiation.
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PMC6735305_01_ZJCH_A_1640016_F0001_OC.jpg
F0001
Cytology of the cerebrospinal fluid confirmed CNS involvement with lymphoma as seen in Figure 1, that lead to the diagnosis of LC secondary to Large B-Cell Lymphoma. 