PMC5726682_01
PMC5726682_02
PMC5726682_03
A: Brown plaques on the anterior aspect of the legs, with
overlying normochromic, smooth surfaced nodules; B and C:
erythematous firm nodules on the eyebrow (B) and forearm
(C) with crusts and hemorrhagic dots
abd-92-05-s1-0069-g01.jpg
PMC5726682_03_abd-92-05-s1-0069-g01.jpg
f1
A: Erythematous plaque on the left leg, with mild scaling;
B and C: red-purple plaque, hardened on palpation, on
the medial aspect of the knee (B) and forearm
(C)
abd-92-05-s1-0069-g02.jpg
PMC5726682_03_abd-92-05-s1-0069-g02.jpg
f2
A: Skin biopsy from the forearm with a granulomatous
inflammatory infiltrate in the dermis, with neutrophils and a large
amount of fungi (Hematoxylin & eosin, X40); B: In
detail, the granuloma with suppuration and fungi with refringent capsule
(Hematoxylin & eosin, X400); C: Fungi capsules were
stained red by the special staining Mayer's mucicarmine (X400).
abd-92-05-s1-0069-g03.jpg
PMC5726682_03_abd-92-05-s1-0069-g03.jpg
f3
A biopsy was taken from the lesions of the patients, and histopathology confirmed the diagnosis of cryptococcosis in all cases (Figure 3).
PMC5726682_04