PMC5726675_01
Subcutaneous nodule on the left hypochondrium
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f1
During examination, besides the presenting complaint, three erythematous, well-defined, symmetrical nodules, with approximately 3cm in diameter were seen on the left hypochondrium, interscapular region and sacrum (Figures 1 and 2).
Subcutaneous nodules on the interscapular region and sacrum
A. Subcutaneous nodule on the interscapular region
B. Subcutaneous nodule on the sacrum
C.
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f2
During examination, besides the presenting complaint, three erythematous, well-defined, symmetrical nodules, with approximately 3cm in diameter were seen on the left hypochondrium, interscapular region and sacrum (Figures 1 and 2).
Cells with atypical small nuclei, attempting to form lines amid a dense
collagenous stroma in the dermis (Hematoxylin & eosin, X100)
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f3
During the assessment of the lesions, histopathology favored the diagnosis of cutaneous metastases of breast cancer and the immunohistochemistry suggested the ductal subtype (Figures 3 and 4).
Diffusely positive immunohistochemistry to AE1 + AE2 A; CK7
B; estrogen receptors C; and progesterone
receptors D (immunohistochemistry, X10)
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f4
During the assessment of the lesions, histopathology favored the diagnosis of cutaneous metastases of breast cancer and the immunohistochemistry suggested the ductal subtype (Figures 3 and 4).