PMC2935546_01
Computed tomography of the lower abdomen showing an exophytic lesion arising from the dome of the bladder (black arrow) and two large diverticulums (white arrows).
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A CT scan of the abdomen showed no perivesical tissue extension, no lymph node enlargement and no hydronephrosis presence (Figure 1).
The immunohistochemical staining profile of the tumor (a) APAP/ a-SMA X 25, and (b) APAP/S-100 X 25.
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Vimentin was diffusely expressed in neoplastic cells and desmin, alpha-SMA, s-100, CD117, CD34 and keratins of low molecular weight were focally positive. (Figures 2(a) and 2(b)).
(a) Numerous cutaneous neurofibromas (small white arrows) and the performance of the ileal stoma (black arrow) located below the right line between umbilicus and the anterior superior iliac spine. (b) Microscopic view of resected cutaneous neurofibroma at the site of the performed stoma (H-E stain X 2.5).
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Additionally due to lack of genetic test to confirm his inherited disease, the excised cutaneous lesions from the site of the performed stoma were sent for histopathologic evaluation (Figure 3).
(a) Intraluminal macroscopic view of cystectomy specimen. Recognition of one out of the two polypoid lesions of urinary mucosa (white arrow). (b) Microscopic view of the ulcerated surface of the polypoid lesion (H-E stain X 2.5).
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Macroscopic view of the cystectomy specimen revealed two polypoid lesions with smooth, elastic surface, 1 and 1,5 cm in diameter located at the bladder dome (Figure 4(a)). The ulcerated surface of the polypoid lesion was recognized microscopically (Figure 4(b)).