PMC4352207_01
Color fundus photographs of the right (A), (B) and the left (C), (D) eyes displaying yellow-brown perivascular lesions ranging from less than 1/2 to 2 DD in size down the superotemporal and inferotemporal vascular arcades, coupled by fibrous bands along the vessel walls.
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F1
This lesion was associated with fibrous bands along the vessel wall (Fig. 1A). Another lesion was also yellow-brown perivasculary located, ranging from less than 1/2 up to 2 DD in size, along the inferotemporal vascular arcade associated with fibrous bands along the vessel wall (Fig. 1B). Fundus examination of the left eye disclosed fibrous bands along the superotemporal and inferotemporal vascular arcades (Fig. 1C), and yellow-brown pigmented perivascular chorioretinal lesions less than 1/2 and 2 DD in size along the superotemporal vascular arcade associated with fibrous bands along the vessel wall (Fig. 1D).
Fundus autofluorescence of the right (A), (B) and the left (C), (D) eyes showing the homogenous increase in autofluorescence corresponding to the perivascular chorioretinal lesion areas.
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F2
Fundus autofluorescence (FAF) of the right eye revealed a homogenous increase in autofluorescence corresponding to the chorioretinal lesions along the superotemporal and inferotemporal vascular arcades (Fig. 2 A, B). Fundus autofluorescence of the left eye revealed a homogenous increase in autofluorescence corresponding to the chorioretinal lesions along the superior vascular arcades (Fig. 2 C, D).Fundus fluorescein angiography (FFA) of the right eye showed perivenous location of the lesions commencing with appearance at arteriovenous and late venous phases indicating changes in vascular calibers around the lesions (Fig. 3 A, B, C).
Fundus fluorescein angiography of the right (A), (B) and (C), as well as the left (D), (E) and (F) eyes disclose perivenous location of the lesions along the superotemporal and inferotemporal vascular arcades associated with staining both at arteriovenous, (A, B, D, E) and late venous phases (C, F) in both eyes. Changes in vascular calibers along the inferotemporal vascular arcade,(A) and superotemporal vascular arcade (B) in the right eye, changes in vascular calibers along the inferotemporal arcade, and vascular occlusion along the superotemporal arcade (D, F) associated with loop vessel formation (E) in the left eye are disclosed.
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F3
Fundus autofluorescence of the left eye revealed a homogenous increase in autofluorescence corresponding to the chorioretinal lesions along the superior vascular arcades (Fig. 2 C, D).Fundus fluorescein angiography (FFA) of the right eye showed perivenous location of the lesions commencing with appearance at arteriovenous and late venous phases indicating changes in vascular calibers around the lesions (Fig. 3 A, B, C). Fundus fluorescein angiography of the left eye revealed perivenous lesions beginning to appear at arteriovenous and late venous phases (Fig. 3 D, E, F), establishing changes in vascular caliber (Fig. 3 D ,F) with formation of vascular loops along the superonasal vascular branch (Fig. 3 E). Down the superotemporal vascular arcade occlusion of the blood flow could be seen around the lesion (Fig. 3 E, F). There was no leakage at the macula at arteriovenous and late venous phases in both eyes (Fig. 3 A, B, D, E, F).
Fundus fluoresce in angiography of the right (A), (B) and (C), and theleft (D), (E) and (F) eyes at the 3rd year of follow-up. Note the stability of inactive perivenous chorioretinal lesions in both eyes.
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F4
The patient was followed for three years without treatment, and neither activation of the lesions on FFA (Fig. 4 A-F), nor were intraocular inflammatory signs observed during her follow up in both eyes.