PMC4199820_01
Fundus photographs and spectral-domain optical coherence tomography (SD-OCT) before and after treatment.. Notes: Images of both eyes of a 33-year-old woman with hypertensive retinopathy (A-D) before treatment and (E-H) 3 months after hypertensive treatment started. (A) Color photograph of the right eye shows retinal hemorrhage, "cotton-wool" spots, papilledema, and macular edema. (B) Horizontal line scan on SD-OCT of the right eye shows serous retinal detachment and hyperreflective foci, representing precursors of hard exudate in the retina. (C) Color photograph of the left eye shows retinal hemorrhage, cotton-wool spots, and papilledema, all of which are milder than those in the right eye. (D) Horizontal line scan on SD-OCT of the left eye shows serous retinal detachment and hyperreflective foci. (E and G) Fundus findings reveal favorable response to hypertensive treatment. (F and H) Horizontal line scans on SD-OCT of both eyes show complete disappearance of serous retinal detachment. The scale bar represents 200 mum. Green arrows represent the sectioned line of the SD-OCT.
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Fundus examination revealed retinal hemorrhage, "cotton-wool" spots, and papilledema in both eyes, with macular edema in the right eye (Figure 1).
Adaptive optics scanning laser ophthalmoscopy (AO-SLO) images of thickened retinal arterial wall.. Notes: (A) AO-SLO image, corresponding to the area outlined in white in Figure 1E, of a retinal artery in controlled hypertensive retinopathy and (B) magnified image of the area outlined in white in (A). (C) AO-SLO image of a retinal artery temporal-superior to the optic disc in a normal subject and (D) magnified image of the area outlined in white in (C). (A) Scale bar =100 mum. (B) The arterial wall (a) is thicker than that of the normal subject in (D). The average wall thickness (a), inner diameter (b), outer diameter (c), and wall-to-lumen ratio of the retinal artery were 18.7 mum, 86.2 mum, 123.7 mum, and 0.44, respectively. (D) The average wall thickness (a), inner diameter (b), outer diameter (c), and wall-to-lumen ratio of the retinal artery were 10.7 mum, 92.4 mum, 113.7 mum, and 0.23, respectively.
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Tokyo, Japan) in a retinal artery of 1-papilla diameter temporal inferior to the optic disc in the right eye (Figure 2). The average wall thickness was 18.7 mum, and the wall-to-lumen ratio was 0.44.