PMC4927635_01
Change in 6-minute walk distance and treatment regimen.
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September of 2004, with immunosuppression alone, her 6MWD improved to 190 m (see Fig. 1), at which point sildenafil 75 mg Q.I.D. was added. She continued with cyclosporine, oral furosemide and 4 L/min oxygen. She has remained on sildenafil 75 mg Q.I.D and the dose of cyclosporine was gradually reduced to 50 mg twice daily with clinical and laboratory remission of AOSD and sustained improvement in 6MWD (Fig. 1).