PMC8590941_01
(A-F) Multiple ulcers with granulation tissue on the face, occipital region of the scalp, neck, shoulder, upper chest, and back. (B, C, D and F) A violaceous border appeared around the ulcers (blue arrow). (F) is the enlargement of the region marked with a red square region in (D).
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Multiple ulcers with granulation tissue at the base of the wound were found on the face, occipital region of the scalp, neck, shoulder, upper chest, and back (Figure 1A-F), with violaceous borders around the ulcers (Figure 1B, C, D and F).
Biopsy specimen from the edge of the ulceration (Hematoxylin and eosin, x10 and x20 magnifications). (A) Histopathological findings showed skin ulceration (asterisk). (B) Massive dermal neutrophilic infiltration mixed with lymphocytic inflammatory infiltrate. (C) Leukocytoclastic vasculitis (blue arrow).
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Histopathological examination from the edge of the ulcer showed skin ulceration (Figure 2A), massive dermal neutrophilic infiltration mixed with lymphocytic inflammatory infiltrates (Figure 2B), accompanied by leukocytoclastic vasculitis (Figure 2C), with no evidence of infection or malignancy.
(A-F) After 5 months, cribriform atrophic scars developed at the sites of the previous lesions (blue arrow). (F) is the enlargement of the region marked with a red square in (D).
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Ulcer size reduction with cribriform atrophic scars indicated significant improvement, and no new skin lesions appeared after 5 months of observation (Figure 3A-F).