PMC9647296_01
Chest computed tomography (CT) findings of the patients before and after
the treatment. In case 1, chest CT at presentation revealed diffuse
ground-glass opacity (GGO), interlobular septal thickening, and
reticular opacity in bilateral lower lobes (a). After steroid treatment,
marked improvement was seen after 4 months (b). In case 2, ill-defined
GGO was noted, mainly in the left lower lung field (c). Three months
after discontinuation of dasatinib, GGO was decreased (d). In case 3,
chest CT showed diffuse GGOs and peribronchial ill-defined nodules in
the bilateral upper lobes, with a small amount of bilateral pleural
effusion (e). With steroid treatment, follow-up chest CT after 1 month
showed resolution of diffuse GGOs in both lungs (f).
10.1177_17534666221135322-fig1.jpg
PMC9647296_03_10.1177_17534666221135322-fig1.jpg
fig1-17534666221135322
CRP, 2.84 mg/dl; procalcitonin, 0.13 ng/ml; aspartate transferase, 47 IU/L; and alanine transferase, 71 IU/L. Chest CT revealed diffuse GGO and peribronchial ill-defined nodules in the bilateral upper lobes, with a small amount of bilateral pleural effusion (shown in Figure 1(e)). She showed symptomatic improvement, and follow-up chest CT showed resolution of diffuse GGOs in both lungs (shown in Figure 1(f)).
Pathologic features of the video-assisted thoracoscopic lung biopsy. The
alveolar walls are thickened by a uniform, cellular, inflammatory
interstitial infiltrate including lymphocytes, plasma cells, and
histiocytes without architectural distortion (hematoxylin and eosin
stain, 1.4x). Inset: Peribronchiolar lymphohistiocytic aggregates and
noncaseating granulomatous inflammation (hematoxylin and eosin stain,
20x).
10.1177_17534666221135322-fig2.jpg
PMC9647296_01_10.1177_17534666221135322-fig2.jpg
fig2-17534666221135322
Histologically, the alveolar walls were thickened by a uniform, cellular, and inflammatory interstitial infiltrate including lymphocytes, plasma cells, and histiocytes without architectural distortion (shown in Figure 2).
PMC9647296_02
Chest computed tomography (CT) findings of the patients before and after
the treatment. In case 1, chest CT at presentation revealed diffuse
ground-glass opacity (GGO), interlobular septal thickening, and
reticular opacity in bilateral lower lobes (a). After steroid treatment,
marked improvement was seen after 4 months (b). In case 2, ill-defined
GGO was noted, mainly in the left lower lung field (c). Three months
after discontinuation of dasatinib, GGO was decreased (d). In case 3,
chest CT showed diffuse GGOs and peribronchial ill-defined nodules in
the bilateral upper lobes, with a small amount of bilateral pleural
effusion (e). With steroid treatment, follow-up chest CT after 1 month
showed resolution of diffuse GGOs in both lungs (f).
10.1177_17534666221135322-fig1.jpg
PMC9647296_03_10.1177_17534666221135322-fig1.jpg
fig1-17534666221135322
CRP, 2.84 mg/dl; procalcitonin, 0.13 ng/ml; aspartate transferase, 47 IU/L; and alanine transferase, 71 IU/L. Chest CT revealed diffuse GGO and peribronchial ill-defined nodules in the bilateral upper lobes, with a small amount of bilateral pleural effusion (shown in Figure 1(e)). She showed symptomatic improvement, and follow-up chest CT showed resolution of diffuse GGOs in both lungs (shown in Figure 1(f)).
PMC9647296_03
Chest computed tomography (CT) findings of the patients before and after
the treatment. In case 1, chest CT at presentation revealed diffuse
ground-glass opacity (GGO), interlobular septal thickening, and
reticular opacity in bilateral lower lobes (a). After steroid treatment,
marked improvement was seen after 4 months (b). In case 2, ill-defined
GGO was noted, mainly in the left lower lung field (c). Three months
after discontinuation of dasatinib, GGO was decreased (d). In case 3,
chest CT showed diffuse GGOs and peribronchial ill-defined nodules in
the bilateral upper lobes, with a small amount of bilateral pleural
effusion (e). With steroid treatment, follow-up chest CT after 1 month
showed resolution of diffuse GGOs in both lungs (f).
10.1177_17534666221135322-fig1.jpg
PMC9647296_03_10.1177_17534666221135322-fig1.jpg
fig1-17534666221135322
CRP, 2.84 mg/dl; procalcitonin, 0.13 ng/ml; aspartate transferase, 47 IU/L; and alanine transferase, 71 IU/L. Chest CT revealed diffuse GGO and peribronchial ill-defined nodules in the bilateral upper lobes, with a small amount of bilateral pleural effusion (shown in Figure 1(e)). She showed symptomatic improvement, and follow-up chest CT showed resolution of diffuse GGOs in both lungs (shown in Figure 1(f)).