PMC9938454_01
Bone marrow aspirate with May Grunwald Giemsa stain. A) 10x shows normocellular bone marrow with dysplastic megakaryocyte. B and C show in 100x large cells with high nuclear cytoplasmatic ratio, large nucleus with evident nucleoli these cells (blast cells) represent 12% of nucleated cells.
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BM evaluation showed hypercellular marrow with trilineage dysplasia and 12% blasts some of them with Auer rods (Figure 1).
PMC9938454_02
Bone marrow aspirate with May Grunwald Giemsa stain. A) 10x shows normocellular bone marrow with numerous dysplastic megakaryocytes. B) shows in 100x a dysplastic megakaryocyte. C shows in 100x granular dysplasia with hipogranulation, and large cells with high nuclear cytoplasmatic ratio, large nucleus and evident nucleoli (blast cells) these cells represent 3% of nucleated cells.
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BM aspirate presented hypercellular marrow with trilineage dysplasia and 3% of myeloblasts without Auer rods (Figure 2). BM trephine sections were hypercellular with dysplastic change in megakaryocyte and granulocytic compartment.