PMC4342859_01
Comparative axial sections of cerebral MRI (T1 after gadolinium injection). a Before imatinib (August 2011). b After 800 mg/day imatinib for 5 months (January 2012). c After ertlotinib, 150 mg/day for 7 months (September 2012). d After erlotinib, 150 mg/day for 28 months (July 2014).
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F1
The MRI showed an extension into the right cavernous sinus (fig. 1a). Imatinib (400 mg/day, then 800 mg/day) was given for 5 months, but the tumour nevertheless progressed toward the frontal lobe (fig. 1b). A partial response was registered in September 2012 (fig. 1c). An MRI (fig. 1d) displayed a persistent partial response (28+ months).