PMC4484564_01
Clinical findings: a tumor measuring about eight millimeters located on the upper border of the right nostril. There was an additional subcutaneous expansion towards the tip of the nose and the columella. The lesion was hemispherical, immobile, sharply demarcated, nonirritated, and painless.
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She did not mention any other symptoms (Figure 1).
Histopathological examination: fibrous connective tissue partly covered by an intact nondysplastic squamous epithelium. The corial connective tissue is infiltrated by nonkeratinizing squamous cells with pleomorphism of size and nuclei, corresponding to a moderately differentiated squamous cell carcinoma (HE-staining, magnification x20, x50, and x100).
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These findings corresponded to a moderately differentiated squamous cell carcinoma (Figure 2).
(a) Combined PET-CT scan with 283 Mbq F 18 FDG and computed tomography with iodine biased contrast agent. Area of screening: scull base till proximal femur. It reveals the large soft tissue mass with a significant increase in metabolic activity (SUV max 22.9) which surrounds the dorsal part of the thoracic esophagus. (b) Multiple cutaneous, muscular, and osseous metastases (SUV max 22.9) in the entire range of screening.
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There were no abnormalities in the head and neck region (Figures 3(a) and 3(b)).