PMC4066820_01
ROC (panel a), Youden (panel b), decision (panel c), and RUT (panel d) curves for the reference model (full line) and the extended model (dashed line). Vertical lines in panels b, c, and d indicate the risk threshold T of 5% and the prevalence P of 28%.
nihms-576789-f0001.jpg
PMC4066820_01_nihms-576789-f0001.jpg
F1
Figure 1(a) shows ROC curves for the models.
Curves showing NRIT, DeltaNBT, DeltaRUT, and wNRIT (full, dashed, dotted, and dash-dotted lines, respectively) when varying the risk threshold on the x-axis. Vertical lines indicate the risk threshold T of 5% and the prevalence P of 28%.
nihms-576789-f0002.jpg
PMC4066820_01_nihms-576789-f0002.jpg
F2
Figure 2 demonstrates that the decision-analytic measures always give concordant recommendations, but that NRIT may give a different recommendation.
Calibration plots for the reference model (panel a) and the extended model (panel b).
nihms-576789-f0003.jpg
PMC4066820_01_nihms-576789-f0003.jpg
F3
The calibration plots for both models are shown in Figure 3.