PMC9945267_01
Cutaneous hematomas on oncology ward admission.
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The physical examination was unremarkable except for diffuse cutaneous hematomas ( Figure 1 ), and he had asthenia with a poor performance status. Through immunohistochemistry, necrotic cells were found to be diffusely reactive for cytokeratin 7 ( Supplementary Figure 1 ).
The trend of platelets, hemoglobin, and fibrinogen in relation to the treatments. Vp16, etoposide; Ig, immunoglobulin; m, methylprednisolone. First, 2nd, 3rd, 4th, 6th, 8th, and 12th cycles of Fox (Folfox); cape, capecitabine.
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The scan with bone window showed an increase in osteostructural subversion with a prevalent thickening character in all bone segments due to an increase in sclerosis ( Supplementary Figure 2 ). The patient was hospitalized and died a few days later.  Figure 2  shows the trend of platelets, hemoglobin, and fibrinogen before and after treatment.