PMC6358367_01
Radiological examinations of the patient. Axial computed tomography (CT) revealed an irregular, well-defined, hyperdense mass in the right temporal lobe (A). On magnetic resonance imaging (MRI), the lesion showed iso- to hypointensity on T1-weighted imaging (B) and heterogeneous intensity on T2-weighted imaging (C); after contrast medium administration, the lesion showed heterogeneous enhancement, and it was located entirely within the temporal parenchyma, not involving the cerebellopontine angle region (D, axial; E, coronal; F, sagittal).
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F1
Brain computed tomography (CT) revealed an irregular, well-defined, hyperdense mass in the right temporal lobe (Fig. 1A). T1-weighted imaging and heterogeneous intensity on T2-weighted imaging in the right temporal lobe; after gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA) administration, the lesion showed heterogeneous enhancement; the tumor did not involve the cerebellopontine angle region (Fig. 1B-F). The operative preliminary diagnosis was meningioma with calcification, and a surgical resection via the right temporal approach was performed.
Histopathological examination of the patient. Hematoxylin-eosin staining revealed hyperchromatic nuclei and loose intercellular matrix with calcification (A, x400). Immunohistochemical analysis demonstrated that the tumor was strongly positive for S100 protein (B, x400).
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F2
Histopathological examination revealed hyperchromatic nuclei and loose intercellular matrix with calcification (Fig. 2A). Immunohistochemical analysis demonstrated the tumor was strongly positive for S100 protein (Fig. 2B) but negative for glial fibrillary acidic protein (GFAP) and cytokeratin (CK), which was consistent with a schwannoma.
Follow-up magnetic resonance imaging. Axial T1-weighted (A), T2-weighted (B), contrasted (C), and diffusion-weighed (D) imaging showed no recurrence.
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F3
After a 6-month follow-up, MRI showed no recurrence (Fig. 3), and the patient remained asymptomatic.