PMC6247670_01
(a, b) Peripheral blood film and bone marrow aspirate showing dual population (x40, May Grunwald Giemsa). (c, d) Bone biopsy with sheets of immature cells with interstitial infiltration and nodular aggregates of lymphocytes, respectively (x40, H&E).
CRIHEM2018-6452843.001.jpg
PMC6247670_01_CRIHEM2018-6452843.001.jpg
fig1
Representative pictures of peripheral blood and bone marrow findings are compiled in Figure 1.
(a) CD45 versus side scatter (SSC) dot plot showing three distinct populations. Lymphocytes: CD45 positive and low side scatter (red color). Monocytic precursors and monocytes: CD45 positive and moderate side scatter (green and blue color, respectively). (b, c) Population in green and blue color was positive for CD64, CD33, and HLA-DR. More mature cells were also positive for CD14. (d-f) Lymphocytes were predominantly B cells and showed dual positivity for CD5 and CD23 with dim kappa and negative FMC7 and CD22.
CRIHEM2018-6452843.002.jpg
PMC6247670_01_CRIHEM2018-6452843.002.jpg
fig2
Immunophenotyping features are compiled in Table 2 and Figure 2.