PMC5876472_01
Pedigree. The proband has 2 male siblings, one of which was diagnosed with Syndenham chorea but has declined genetic testing. The proband's father has mild generalized myoclonus and was found to have the same mutation. His father was reportedly 'jerky' but is now deceased.
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Supplementary Figure 1). She graduated from a high school special education program and enrolled in a few community college courses with special accommodations. The proband's brother had been previously diagnosed with Sydenham's chorea (see Figure 1).
Video of Neurological Exam. Mild cervical dystonia with left turn. Myoclonus affecting the neck and trunk. Myoclonus is elicited by auditory and tactile stimuli and worsened in the trunk and arms with posture and intention. The gait is slightly wide based and appears hypotonic. Handwriting induces worsening of cervical dystonia and neck and truncal myoclonus. Myoclonus affects handwriting and water pouring.
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Supplementary Figure 1). She graduated from a high school special education program and enrolled in a few community college courses with special accommodations. The proband's brother had been previously diagnosed with Sydenham's chorea (see Figure 1).