PMC6939419_01
Case 1. (a) Ultrasonographic findings at 36 weeks of gestation. Heterogeneous high echoic mass-like debris within the fetal stomach (white arrow) and uterus (red arrow). Linear echo findings around the umbilical cord (blue arrow) and chorioamniotic membrane separation (green arrow). (b) Macroscopic findings. Umbilical ulcer with exposed umbilical cord artery (white arrowhead). The amniotic and chorionic membranes were separated on the surface of the placenta (blue arrowhead). (c) Original magnification. Loss of the amniotic membrane, degeneration of the umbilical cord stroma, and exposure of the umbilical cord artery (black arrowhead, hematoxylin and eosin; H&E, x40).
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fig1
At 36 weeks of gestation, fetal ultrasound findings showed heterogeneous high echoic mass-like debris within the uterus and fetal stomach, linear echo around the umbilical cord, and chorioamniotic membrane separation (Figure 1(a)). Macroscopically, two UCUs with exposed umbilical artery were observed at the umbilical cord surface attached to the placenta (Figure 1(b)). The amniotic and chorionic membranes were separated from the surface of the placenta (Figure 1(b)). Histopathological examination revealed amniotic membrane loss, umbilical cord stroma degeneration, and umbilical artery exposure (Figure 1(c)).
PMC6939419_02
Case 2. (a) Ultrasonographic findings at 36 weeks of gestation. Heterogeneous high echoic mass-like debris within the uterus (red arrow) and linear echo finding around the umbilical cord (blue arrow). (b) Macroscopic findings. Umbilical ulcer with perforation of umbilical cord artery (white arrowhead). (c) Original magnification. Focal perforation of the umbilical cord artery with thinning of Wharton's jelly (black arrowhead, H&E, x100).
CRIOG2019-3768761.002.jpg
PMC6939419_02_CRIOG2019-3768761.002.jpg
fig2
On fetal ultrasound examination, heterogeneous high echoic mass-like debris within the uterus and linear echo findings around the umbilical cord were detected (Figure 2(a)). Macroscopically, one UCU with umbilical artery perforations and one UCU with exposed umbilical artery were observed at the umbilical cord surface attached to the placenta and fetus (Figure 2(b)). Histopathological examination revealed focal perforation of the umbilical cord artery with thinning of Wharton's jelly (Figure 2(c)).