PMC10246311_01
A 21-year-old Vietnamese woman with a palpable tumor in her right breast. An irregularly shaped hypoechoic mass (arrow) in the left breast was detected using color-Doppler mode ultrasound.
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F1
The lesion was subsequently categorized as BIRADS 4A [Figure 1].
A 21-year-old Vietnamese woman with a palpable tumor in her right breast. A hyperintense lesion (arrow) was seen on short tau inversion recovery (a). A restricted diffusion lesion was seen via diffusion-weighted imaging (b) and the apparent diffusion coefficient map (c). The lesion (arrow) showed a fast-initial increase on dynamic T1-weighted imaging with contrast enhancement, followed by a plateau enhancement in the delayed phase (d and e).
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F2
The lesion was non-mass and mildly hyperintense, with a focal distribution, on STIR imaging [Figure 2a] The lesion was hyperintense on diffusion-weighted imaging and hypointense on the apparent diffusion coefficient map [Figure 2b and c]. T1-weighted imaging with contrast, the lesion exhibited a fast initial rise followed by a plateau enhancement during the delayed phase [Figure 2d and e].
Photomicrographs of the histopathological specimen. Ductal carcinoma in situ arising from microglandular adenosis/ atypical microglandular adenosis (MGA/AMGA) (H and E x100) (a). S100 was strongly positive and pervasive in all MGA/AMGA regions (S100 x20, x50) (b and c). P63 was negative in the MGA/ AMGA regions, indicating a lack of myoepithelium (p63 x20) (d).
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F3
AMGA and DCIS [Figure 3a] that showed no signs of infiltrating the basement membrane of the invasive ductal carcinoma (IDC). All margins were negative for DCIS, and the shortest distances from DCIS to the posterior and anterior margins were 0.1 mm and 0.15 mm, respectively; the anterior margin was MGA and the posterior margin was AMGA. MGA/AMGA regions [Figure 3b and c]. Moreover, p63 negativity indicated a lack of myoepithelium in the MGA/AMGA [Figure 3d].