PMC3182544_01
Graph showing changes in revised ALS functional rating scale (ALSFRSR), forced vital capacity (FVC) in litres, weight (in kg), growth hormone (GH) and serum insulin-like growth factor-1 (IGF1) levels over time from first ALS symptom onset. The near linear decline in ALSFRSR is not obviously adversely affected by treatment of the concurrent acromegaly.
ukmss-36065-f0001.jpg
PMC3182544_01_ukmss-36065-f0001.jpg
F1
These measures were plotted against serum IGF-1 and GH levels (Figure 1).