PMC4373317_01
Fundus photography showing new active cytomegalovirus retinitis OU at presentation (A,B). At 2 week follow-up after biweekly intravitreal ganciclovir injections in both eyes, some worsening retinitis is noted OD (C) with minimal improvement OS (D). Fundus photography six weeks later, after two rounds of three cycles of CMV-specific T-cell infusion, showing marked consolidation with almost complete resolution of any areas of active retinitis (E,F). Fundus photography at 3 month follow-up showing completely inactive retinitis off antiviral therapy (G,H).
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F1
Fundoscopy revealed vision-threatening CMV retinitis OU (Figure 1A,B). Biweekly intravitreal ganciclovir injections (2mg/0.1mL) were administered 3 times OD and 4 times OS, with worsening retinitis OD and modest response in retinitis OS (Figure 1C,D). Retinitis completely resolved and remained inactive during the 3 month follow-up (Figure 1E-H).