PMC5395261_01
BCR-ABL tyrosine kinase domain mutation analysis in peripheral blood revealed c.839T>G (V280G mutation), in which GTG GGG (valine to glycine).
10.1177_1179554917702870-fig1.jpg
PMC5395261_01_10.1177_1179554917702870-fig1.jpg
fig1-1179554917702870
This study showed a mutation on amino acid 280, resulting in the substitution of valine (V) by glycine (G), present in all transcripts (c.839T>G V280G mutation) (Figure 1), and negative in DNA samples from the gum mucosa.