PMC5491826_01
The CT findings of Case 1 (A-C) and Case 2 (D and E) on admission. An abdominal CT scan shows hepatosplenomegaly (arrows) and bilateral pleural effusion (arrow heads) (A), right adrenal hemorrhaging (arrow) (B), and multiple lymphadenopathy (arrows) (C). An enhanced abdominal CT scan shows hepatosplenomegaly (arrows) and ascites (arrow head) (D), and multiple lymphadenopathy (arrow) and ascites (arrow head) (E).
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A CT scan showed pleural and abdominal fluid, hepatosplenomegaly, and systemic lymphadenopathy (Fig. 1D and E).
The pathological findings of cervical lymph nodes and bone marrow of Case 1 (A-D) and Case 2 (E-H). Lymph node biopsy specimens show atrophic germinal centers and interfollicular plasma cell proliferation (A: x100, B: x200,), and atrophic germinal center (E: x100, F: x200). Hematoxylin-Eosin staining. Lymph node biopsy specimens show CD21+follicular dendritic cell proliferation (C and G: x100). CD21 immunostaining. Bone marrow biopsy specimens show mild fibrosis (D and H: x400). Silver staining.
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A cervical lymph node biopsy showed atrophic germinal centers (Fig. 2E and F). Immunostaining for CD21 showed follicular dendritic cell proliferation (Fig. 2G). B cell lymphoma. Bone marrow aspiration and a bone marrow biopsy revealed slight fibrosis without atypical cells (Fig. 2H).
PMC5491826_02
The CT findings of Case 1 (A-C) and Case 2 (D and E) on admission. An abdominal CT scan shows hepatosplenomegaly (arrows) and bilateral pleural effusion (arrow heads) (A), right adrenal hemorrhaging (arrow) (B), and multiple lymphadenopathy (arrows) (C). An enhanced abdominal CT scan shows hepatosplenomegaly (arrows) and ascites (arrow head) (D), and multiple lymphadenopathy (arrow) and ascites (arrow head) (E).
1349-7235-56-1247-g001.jpg
PMC5491826_02_1349-7235-56-1247-g001.jpg
g001
A CT scan showed pleural and abdominal fluid, hepatosplenomegaly, and systemic lymphadenopathy (Fig. 1D and E).
The pathological findings of cervical lymph nodes and bone marrow of Case 1 (A-D) and Case 2 (E-H). Lymph node biopsy specimens show atrophic germinal centers and interfollicular plasma cell proliferation (A: x100, B: x200,), and atrophic germinal center (E: x100, F: x200). Hematoxylin-Eosin staining. Lymph node biopsy specimens show CD21+follicular dendritic cell proliferation (C and G: x100). CD21 immunostaining. Bone marrow biopsy specimens show mild fibrosis (D and H: x400). Silver staining.
1349-7235-56-1247-g002.jpg
PMC5491826_02_1349-7235-56-1247-g002.jpg
g002
A cervical lymph node biopsy showed atrophic germinal centers (Fig. 2E and F). Immunostaining for CD21 showed follicular dendritic cell proliferation (Fig. 2G). B cell lymphoma. Bone marrow aspiration and a bone marrow biopsy revealed slight fibrosis without atypical cells (Fig. 2H).