PMC9534698_01
(a) Renal biopsy showing remarkable infiltration of eosinophils in the interstitium of the kidney (scale bar: 100 mum). (b) Fibrinoid necrosis visible in the interlobular arteries of the kidney (scale bar: 50 mum). (c) One glomerulus, showing glomerular crescent formation (scale bar: 50 mum). (d) Rupture of the glomerular basement membrane in this glomerulus, which appears to have spread from outside of the glomerulus; the yellow arrows indicate infiltration from the interstitium (scale bar: 50 mum). A B: haematoxylin and eosin staining, C D: periodic acid methenamine silver staining).
CRIRH2022-9606981.001.jpg
PMC9534698_01_CRIRH2022-9606981.001.jpg
fig1
These histopathological findings suggested that glomerulonephritis and interstitial nephritis had developed from the spread of inflammation originating from the interlobular arteries of the kidney (Figure 1).