PMC6005287_01
Dorsocervical subcutaneous masses in a dog who received three vaccinations at this site three weeks previously.
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fig1
Photomicrograph of a soft tissue sarcoma at an injection site in a dog. Hematoxylin and eosin stain.
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fig2
The mitotic count was 20 in 10 high powered fields (HPF, FN22), and there were occasional bizarre mitotic figures (Figure 2).
Positive immunohistochemical staining of the tumor for (a) VEGFr and (b) PDGFr.
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fig3
Neoplastic cells were immunohistochemically positive for Vascular Endothelial Growth Factor receptor (VEGFr) (Figure 3(a)), Platelet Derived Growth Factor receptor (PDGRr) (Figure 3(b)), Stem Cell Factor (SCF), and Epithelial Growth Factor Receptor (EGFR) and negative for VEGF, PDGR, KIT, and p-53.