PMC9586834_01
T1 and T2 FLAIR sections of magnetic resonance imaging show hyper signal intensity involving the bilateral hypothalamus.
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T2/FLAIR lesion involving the bilateral hypothalamus with modest perilesional edema (Figure 1). The pathology of the thyroid and lymph node biopsies revealed aggregation of histiocyte-like cells, some of which had nuclear grooves. The immunohistochemistry was positive for CD1a and
The core biopsy shows the aggregation of histiocyte-like cells, some of which show nuclear grooves. Mitosis and necrosis are not observed.
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fig2
S100, which was compatible with Langerhans cell histiocytosis (LCH) (Figure 2). She had no family history of LCH.
Time course of sodium levels.
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fig3
Her serum sodium level had returned to normal after three days.  Figure 3 demonstrates the time course of the serum sodium concentration.