PMC9897691_01
Intraoperative hemoglobin, platelet, and fibrinogen levels; EX-test MCF and CT; FIB-test MCF; and PT.. The times shown are after anesthesia induction (baseline), after drawing autologous blood (before CPB induction), before administration of terminal warm cardioplegia (before CPB weaning), after CPB weaning with protamine (after CPB weaning), and after returning autologous blood (end of surgery).
MCF, maximum clot firmness; CT, clotting time; PT, prothrombin time; CPB, cardiopulmonary bypass
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FIG1
The lowest Hb level recorded was 7.2 g/dL (immediately before CPB weaning); however, it increased to 9.7 g/dL at the end of the surgery (Figure 1a). CPB weaning; these parameters did not return to their presurgery levels even after returning autologous blood (Figures 1b, 1c, 1e, 1f). Conversely, even though the clotting times in the EX-test and PT were prolonged after protamine antagonization, they returned to their presurgery levels at the end of the surgery (Figure 1d, 1g). Clot formation was well in the operative field, the field was dry, and there were no hemostasis problems.