PMC4159397_01
Ultra-wide field color fundus photograph of the right and left eye depicting diffuse midperipheral chorioretinal atrophy with sparing of the central macula.. Note: The left eye also has central submacular fibrosis.
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In the left macula, there was a subfoveal elevated gray-white membrane with an adjacent punctate area of subretinal hemorrhage (Figure 1).
Spectral domain optical coherence tomography horizontal line scan of the left eye prior to development of vision loss, at presentation, and at last follow-up.. Notes: Intact outer retinal structures centrally with normal foveal contour and peripheral outer retinal and retinal pigment epithelium atrophy (A). Subretinal hyper-reflective material in the central macula consistent with fibrosis with trace subretinal fluid and mild intraretinal fluid overlying an area of retinal pigment epithelium and choroidal atrophy nasally (B). Mild improvement in nasal intraretinal fluid and subretinal fibrosis with resolution of subretinal fluid after four intravitreal bevacizumab injections (C).. Abbreviations: min, minimum; max, maximum; vol, volume; ETDRS, Early Treatment Diabetes Retinopathy Study.
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Spectral domain optical coherence tomography (SD-OCT) (Figure 2) and fluorescein angiography (FA) (Figure 3) revealed a subretinal membrane with late staining and mild leakage. Clinical exam appeared stable and SD-OCT revealed mild anatomical improvement (Figure 2).
Fluorescein angiogram (FA) transiting the left eye reveals diffuse atrophy of the choriocapillaris sparing the central macula.. Notes: A central hyperfluorescent lesion in the early images stains (00:29) in the late angiographic images centrally (04:28) (arrowhead). Mild leakage is apparent nasally (arrow).
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Spectral domain optical coherence tomography (SD-OCT) (Figure 2) and fluorescein angiography (FA) (Figure 3) revealed a subretinal membrane with late staining and mild leakage.