PMC5573798_01
MRI Brain FLAIR images axial (A) and sagittal (B) of patient 1 showed bilateral medial temporal hyperintensities. MRI FLAIR images axial (C) in two months, follow-up showed diffuse brain atrophy and persistence of medial temporal hyperintensities. PET CT Brain at presentation (D) showed bilateral basal ganglial and amygdalar hypermetabolism. PET CT Brain at two-month follow-up (E) showed bilateral basal ganglial hypermetabolism and disappearance of medial temporal hypermetabolism. Ictal EEG (F,G) showed movement artifacts with the jerk followed by brief attenuation and build-up of right temporal spikes. MRI Brain axial images T2 (H), FLAIR (I) and T1 (J) in patient 2 showed basal ganglia hyperintensities. T2 axial images (K) also showed left sided substantia nigra hyperintensity (white arrow).
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PMC5573798_02_gr1.jpg
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T1, T2 and FLAIR hyperintensities involving the bilateral caudate nuclei and putamen (Fig. 1H,I&J) and the substantia nigra on the left side (Fig. 1K). The left hippocampus was edematous.
PMC5573798_02
MRI Brain FLAIR images axial (A) and sagittal (B) of patient 1 showed bilateral medial temporal hyperintensities. MRI FLAIR images axial (C) in two months, follow-up showed diffuse brain atrophy and persistence of medial temporal hyperintensities. PET CT Brain at presentation (D) showed bilateral basal ganglial and amygdalar hypermetabolism. PET CT Brain at two-month follow-up (E) showed bilateral basal ganglial hypermetabolism and disappearance of medial temporal hypermetabolism. Ictal EEG (F,G) showed movement artifacts with the jerk followed by brief attenuation and build-up of right temporal spikes. MRI Brain axial images T2 (H), FLAIR (I) and T1 (J) in patient 2 showed basal ganglia hyperintensities. T2 axial images (K) also showed left sided substantia nigra hyperintensity (white arrow).
gr1.jpg
PMC5573798_02_gr1.jpg
f0005
T1, T2 and FLAIR hyperintensities involving the bilateral caudate nuclei and putamen (Fig. 1H,I&J) and the substantia nigra on the left side (Fig. 1K). The left hippocampus was edematous.