PMC5009580_01
Patient 1. Serial magnetic resonance images demonstrate that the glioblastoma arises at the site of encephalomalacia resulting from the brain injury to the left frontal lobe. All images are T2 sequences, except the last one, which is T1 postgadolinium
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F1
Serial imaging after the injury demonstrated encephalomalacia and gliosis at the site of the contusion [Figure 1]. Magnetic resonance imaging (MRI) of the brain revealed a large 4 cm heterogeneously enhancing tumor with a necrotic center in the left frontal lobe [Figure 1].
PMC5009580_02
Patient 2. Serial computed tomography scans spanning a 73-month period show that the glioblastoma in the inferior right frontal lobe developed at the site of the contusion. All images are without contrast, except the last one
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F2
This patient is a 54-year-old right-handed man who suffered a large contusion and severe injury to the inferior right frontal lobe in an automobile accident at age 47 [Figure 2].