PMC10149062_01
Bone marrow aspirate showing hemophagocytosis (Wright-Giemsa staining, x1000).
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We found his leukocytes, hemoglobin and platelets were decreased; ferritin was raised; liver dysfunction, fibrinogen and natural killer (NK) cell activity decreased; and hemophagocytosis was present in bone marrow aspiration (Figure 1).
Change of laboratory parameters. The patient was treated with ruxolitinib on the 24th day after admission (green dotted line).
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The patient's symptoms improved significantly one week later, including the relief of fever and cognitive function, as well as the improvement of blood cell count, fibrinogen and ferritin (Figure 2).
Timeline of the clinical course of the patient.
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The clinical course of this patient is shown in Figure 3.