PMC9640920_01
Morphological examination of bone marrow cells. Megakaryocytes proliferate actively. The ratio of platelet- producing megakaryocyte was decreased, and platelets were few (x100, x400).
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F1
The bone marrow puncture was performed and bone marrow smear showed megakaryocytes was actively proliferating and no malignant lesions (Figure 1).
A case of adalimumab-induced severe thrombocytopenia with treatment process. DEX, dexamethasone; PDN, prednisone; MP, methylprednisolone; rh-TPO, recombinant human thrombopoietin; IVIG, intravenous immune globulin.
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F2
Treatment process is shown in (Figure 2).
The change of platelet count. The patient was admitted with severe thrombocytopenia on the first day, and that the platelet count returned to normal after 29 days of continuous treatment.
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F3
Blood routine examination showed that platelet count increased to normal level and maintained (Figure 3).