PMC5632474_01
The first presentation of the lesion, after topical corticosteroids applications.
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In particular an aphthous lesion on the buccal mucosa was present for more than 40 days, in spite of topical cortisone applications, with significant pain symptoms and with repercussions on nutrition reported by the patient (Figure 1).
The lesion after light diode applications (wavelength of 630 nm with cycles from 30 seconds, 10 consecutive times).
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After a few days, a curious phenomenon happened: healing of Afta Major starting from the center, which was almost completely healed towards the borders of the lesion (Figure 2).
The lesion completely healed after a week.
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After a week the wound had healed completely (Figure 3).