PMC6644278_01
Axial & coronal view, CT of abdomen without contrast demonstrating multifocal left renal malignancy (dashed arrows) with metastasis to vagina as well as left hepatic lobe (solid arrows).
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fig1
CT imaging findings were consistent with a multifocal left renal malignancy with metastasis to vagina as well as left hepatic lobe (Figures 1 and 2).
Axial & coronal view, CT of abdomen without contrast demonstrating multifocal left renal malignancy (dashed arrows) with metastasis to vagina as well as left hepatic lobe (solid arrows).
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fig2
CT imaging findings were consistent with a multifocal left renal malignancy with metastasis to vagina as well as left hepatic lobe (Figures 1 and 2).
Pelvic arteriogram demonstrating a large hypervascular blush with active extravasation (arrow) along the left side of the vagina consistent with metastatic lesion.
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fig3
A pelvic arteriogram was performed and showed a large hypervascular mass with active extravasation of the left vagina consistent with metastatic disease (Figure 3).
Vaginal mass biopsy: Hematoxylin and Eosin stain at 40X magnification.
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Two formalin-fixed biopsy specimens measuring 0.45 x 0.45 x 0.15 cm and 0.5 x 0.4 x 0.2 cm in size were sent to pathology for consideration (Figure 4).
Vaginal mass biopsy: demonstrating positive reactivity for immunohistochemical PAX8 Stain, consistent with RCC.
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The two specimens were found to be positive for vimentin, CK8/18, AE1/3, CD10, and PAX8 (Figures 5 and 6).
Vaginal mass biopsy: demonstrating positive reactivity for immunohistochemical CD10 Stain, consistent with RCC.
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fig6
The two specimens were found to be positive for vimentin, CK8/18, AE1/3, CD10, and PAX8 (Figures 5 and 6).