PMC8161734_01
Computed tomography (CT) pulmonary angiogram study showing (A) segmental pulmonary emboli, and (B) basal consolidation.. CT head showing (C) petechial hemorrhagic transformation (D) ischaemic changes in the brain.
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CT pulmonary angiography (CTPA) on day 11 revealed a segmental pulmonary embolism in the left lower lobe with peripheral consolidation in lower lobes and right upper lobe (Fig. 1A and B). Repeat CT head showed new petechial haemorrhages within the known right ACA infarct with no mass effect (Fig. 1C and D).
A - Angio-invasive fungus in the lung infarct showing broad irregular aseptate hyphae (mucor).. B - Angio-invasive mucor in the lung - Grocott stain.. C - Angio-invasive mucor in the lung - PAS stain.. D - Mucor in the hilar node.. E - Cerebral mucor- Grocott stain.. F - Mucor fibrinous pericarditis.
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At autopsy, disseminated mucormycosis involving the lungs (a focus of necrosis of about 5 cms in the right lower lobe with evidence of invasive mycosis with broad aseptate hyphae which was Mucorales PCR positive on microscopy), pericardium, hilar nodes, and brain was identified (Fig. 2A-F).