PMC8298140_01
CT scan showing cecal tumor with small bowel distension and air in the retroperitoneal space.
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fig1
CT scan revealed signs of peritonitis with psoas abscess and free air in the retroperitoneal space (Figure 1).
Operating view showing signs of retroperitoneal perforation after right colectomy.
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fig2
Intestinal anastomosis was not performed due to the high risk of leak (Figure 2).
Low magnification HE stain showing tumor proliferation organized in solid islands infiltrating the chorion.
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fig3
Tumor cells were positive for P63 and negative for neuroendocrine tumors biomarkers (Chromogranin A and Synaptophysin) with a Ki-67 proliferation index estimated to 90% (Figures 3-6).
high magnification HEx40, polygonal tumor cells with moderately atypical nuclei and abundant eosinophilic cytoplasm.
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fig4
Tumor cells were positive for P63 and negative for neuroendocrine tumors biomarkers (Chromogranin A and Synaptophysin) with a Ki-67 proliferation index estimated to 90% (Figures 3-6).
Immunohistochemistry HEX20 intense nuclear marking of tumor cells at P63.
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fig5
Tumor cells were positive for P63 and negative for neuroendocrine tumors biomarkers (Chromogranin A and Synaptophysin) with a Ki-67 proliferation index estimated to 90% (Figures 3-6).
HEx20 Ki67 estimated to more than 9%.
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fig6
Tumor cells were positive for P63 and negative for neuroendocrine tumors biomarkers (Chromogranin A and Synaptophysin) with a Ki-67 proliferation index estimated to 90% (Figures 3-6).