PMC4347607_01
Coronal slices taken 6 mm apart starting posteriorly at y = 22 and showing the extent of the tumor resection in the right hemisphere. The resection encompassed right superior frontal gyrus and right middle frontal gyrus, including Brodmann areas 9, 46, and 10. Right inferior frontal gyrus was almost completely spared. In Talairach normalized space, the resection extended from x of 0 (midline) to about 50 mm, y of 23 to y of 66 mm (anterior tip of brain) and z of -4 to z of 50 mm (superior tip of brain).
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F1
Figure 1 shows the extent of the cortical resection in the patient's brain.
Schematic showing the various tasks administered to patient and controls. (A) Schematic of the Endogenous Cueing Task. (B) Schematic of the Exogenous Cueing Task. (C) Schematic of the Exogenous Cueing Task with Explicit Reorienting. ISI, Inter-stimulus Interval is the time between the cue and stimulus. ISI for the Endogenous Cueing Task was fixed at 100 ms; ISI for Exogenous Cueing Task was 0, 100, 250, 500 or 700 ms; ISI for the Exogenous Cueing Task with Explicit Reorienting was 100, 400 or 800 ms. Subjects were instructed to indicate the orientation of the Gabor Patch with a button press during the Response window (Gray Fixation).
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F2
In this experiment participants were asked to covertly direct their attention in a top-down manner to a cued location (see Figure 2A). In this experiment participants were shown an exogenous stimulus (a white box) at one of two locations, to the left or right of fixation (see Figure 2B). This task consisted of three trial types including: implicit exogenous cueing, exogenous cueing with explicit reorienting, and control trials (see Figure 2C).