PMC4717649_01
Hives developed on mid-back and right forearm 20 minutes following ingestion of full dose of amoxicillin
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PMC4717649_01_13256_2016_801_Fig1_HTML.jpg
Fig1
The oral challenge was positive as she developed hives 20 minutes following ingestion of the full dose (Fig. 1).
PMC4717649_02
a. Erythematous maculopapular rash that coalesced to form large raised plaques developed on day 8 of treatment with amoxicillin. b. Erythematous plaques developed on his face, back, thighs and arms 18 hours following oral challenge to amoxicillin
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PMC4717649_02_13256_2016_801_Fig2_HTML.jpg
Fig2
On the eighth day of treatment, he developed a maculopapular rash (Fig. 2a) that coalesced to form large raised plaques. He had no reactions initially, but approximately 18 hours later he developed non-pruritic erythematous plaques on his face, thighs and arms (Fig. 2b).
PMC4717649_03
a. Hives developed throughout his body on day 3 of treatment with amoxicillin. b. Hives developed 15 minutes following ingestion of one tenth of weight-based dose of amoxicillin. c. Results of intradermal testing showing wheal size of 8x16 mm (wheal/erythema)
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PMC4717649_03_13256_2016_801_Fig3_HTML.jpg
Fig3
A healthy 14-month-old Chinese boy presented with hives on the third day of amoxicillin treatment for otitis media shortly after he woke up from his sleep and prior to his morning dose (Fig. 3a). The oral challenge was positive because he developed hives 15 minutes (Fig. 3b) following ingestion of one tenth of his weight-based dose of amoxicillin. An intradermal test with Pre-Pen  (benzylpenicilloyl polylysine) was positive (Fig. 3c).