PMC5312193_01
Lesion with nodular aspect next to the proximal nail fold on the third
right finger. Convexity and depressions on the plate
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f1
Adjacent skin revealed a mild erythema (Figure 1).
On translucency examination, presence of translucent circular areas
forming halos
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f2
On translucency examination, the lesion became more evident and well defined (Figure 2).
Surgical exploration revealed multilobulated tumor with smooth and shiny
surface in xanthomatous tissue
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f3
We performed an uneventful excision of the nailfold (Figure 3).
Histiocytic proliferation forming giant cells similar to osteoclasts.
Presence of macrophages, collagen, and hyaline fibrous tissue
(Hematoxylin & eosin x10)
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f4
Histopathology revealed multinucleated giant cells surrounded by round cells and collagen rich hypocellular areas, as well as areas with xanthomatous histiocytes in surrounded by round cells, suggesting the diagnosis of tenosynovial giant cell tumor (Figures 4 and 5).
Xanthomatous histiocytic differentiation. Proliferation of histiocytes
and fibroblasts in xanthomatous areas (Hematoxylin & eosin x10)
abd-92-01-0121-gf05.jpg
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f5
Histopathology revealed multinucleated giant cells surrounded by round cells and collagen rich hypocellular areas, as well as areas with xanthomatous histiocytes in surrounded by round cells, suggesting the diagnosis of tenosynovial giant cell tumor (Figures 4 and 5).
Satisfactory postopera - tive evolution without signs of recurrence after
two months
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f6
The patient presented good postoperative evolution without signs of local recurrence to date (Figure 6).