PMC4977969_01
The Papanicolaou stain cytology smear slide shows numerous papillary groups of epithelioid cells in a background of lymphoid cells (x100)
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F1
Pap-stained smear slides showed numerous papillary groups of epithelioid cells in a background of lymphoid cells [Figure 1]. Psammomatous calcifications were also noted.
The Papanicolaou stain cytology smear slide shows that the epithelioid cells were relatively uniform. The cells had a high nuclear-to-cytoplasmic ratio. The nuclei were predominantly oval and exhibited fine nuclear chromatin. Quite prominent nuclear grooves and irregular nuclear membrane were also noted (x400)
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F2
Prominent nuclear grooves and irregular nuclear membrane were also observed [Figure 2].
The Papanicolaou stain cytology smear slide shows several psammoma bodies associated with tumor cells (x400)
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F3
Psammomatous calcifications were also noted [Figure 3].
The needle core biopsy shows deposits of tubular and papillary groups of tumor cells with psammomatous calcification in the background of lymphoid tissue (H and E, x200)
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F4
The needle core biopsy showed extensive deposits of tubular and papillary groups of tumor cells with psammomatous calcification in the background of lymphoid tissue [Figure 4].
The tumor cells are immunoreactive with estrogen receptor (x200)
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F5
The tumor cells were immunoreactive for estrogen receptor (ER) and WT-1 [Figures 5 and 6], whereas they were nonreactive for thyroid transcription factor-1 (TTF-1) and thyroglobulin.
The tumor cells are immunoreactive (nuclear staining) with WT-1 (x200)
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F6
The tumor cells were immunoreactive for estrogen receptor (ER) and WT-1 [Figures 5 and 6], whereas they were nonreactive for thyroid transcription factor-1 (TTF-1) and thyroglobulin.