PMC6526567_01
Antibiograms and MICs of Granulicatella adiacens and Abiotrophia defectiva strains isolated from the clinical cases. (a) Case 1 G. adiacens strain MICs. (b) Case 2 G. adiacens strain MICs. (c) Case 3 A. defectiva strain MICs.
CRIID2019-5038563.001.jpg
PMC6526567_03_CRIID2019-5038563.001.jpg
fig1
A. defectiva strain showed a reduced penicillin and ampicillin susceptibility (Figure 1(c)); thus, a glycopeptide-based antibiotic regimen was started. A transthoracic echocardiography showed a severe mitral insufficiency without evidence of vegetations.
PMC6526567_02
Antibiograms and MICs of Granulicatella adiacens and Abiotrophia defectiva strains isolated from the clinical cases. (a) Case 1 G. adiacens strain MICs. (b) Case 2 G. adiacens strain MICs. (c) Case 3 A. defectiva strain MICs.
CRIID2019-5038563.001.jpg
PMC6526567_03_CRIID2019-5038563.001.jpg
fig1
A. defectiva strain showed a reduced penicillin and ampicillin susceptibility (Figure 1(c)); thus, a glycopeptide-based antibiotic regimen was started. A transthoracic echocardiography showed a severe mitral insufficiency without evidence of vegetations.
FDG-PET/CT scan of patient 2 showing an intense metabolic uptake between the lower plate of L5 and the upper plate of S1.
CRIID2019-5038563.002.jpg
PMC6526567_02_CRIID2019-5038563.002.jpg
fig2
To determine if the morphostructural bone changes described in MRI were metabolically active, a total body FDG-PET/CT scan was performed: an intense L5-S1 standardized uptake value (SUV = 7.1) was detected (see Figure 2) and diagnosis of native vertebral osteomyelitis was made; no other metabolically active areas were detected.
PMC6526567_03
Antibiograms and MICs of Granulicatella adiacens and Abiotrophia defectiva strains isolated from the clinical cases. (a) Case 1 G. adiacens strain MICs. (b) Case 2 G. adiacens strain MICs. (c) Case 3 A. defectiva strain MICs.
CRIID2019-5038563.001.jpg
PMC6526567_03_CRIID2019-5038563.001.jpg
fig1
A. defectiva strain showed a reduced penicillin and ampicillin susceptibility (Figure 1(c)); thus, a glycopeptide-based antibiotic regimen was started. A transthoracic echocardiography showed a severe mitral insufficiency without evidence of vegetations.