PMC1236932_01
Cranial MRI (FLAIR) on the day of admission showing multiple lesions of the supratentorial grey and white matter.
1471-2377-5-16-1.jpg
PMC1236932_01_1471-2377-5-16-1.jpg
F1
Magnetic resonance (MR) scans performed 24 hours after acute onset of focal symptoms showed disseminated hyperintensities of the supratentorial grey and white matter with predominance in the right occipital region lacking enhancement after GdDTPA-injection (Figure 1).
Leptomeningeal arteries show severe transmural inflammation with lumen obliteration (asterisk). The arrow indicates a fibrinoid necrosis in the vessel wall.
1471-2377-5-16-2.jpg
PMC1236932_01_1471-2377-5-16-2.jpg
F2
The postmortem examination revealed primary angiitis of the central nervous system (PACNS) with focal granulomatous inflammation and partially thrombotic occlusion of leptomeningeal and cerebral arteries (Figure 2) resulting in multiple acute infarction areas in the cerebrum.