PMC6398058_01
Computed tomography of the chest and abdomen depicted bilateral pleural effusion (arrows) (a, b) and ascites (arrowheads) (c). Axillary lymph adenopathy (circles) (b) and inguinal lymph adenopathy (circles) (d) were present.
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fig1
A contrast-enhanced computed tomography (CT) scan of the chest and the abdomen revealed bilateral pleural effusion and ascites with lymphadenopathy (Figure 1).
Appearance of bilateral pleural effusion of the chest was lightly bloody and chylous from each thoracic cavity.
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fig2
Bilateral pleural effusion samples appeared chylous (Figure 2) with high triglyceride concentrations (Table 2) and class III cytology.
Histological findings of the right inguinal lymph node displayed diffuse architectural effacement (a). Neoplastic cells were medium- to large-sized with nuclear pleomorphism (b).
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fig3
A biopsy obtained from the right inguinal lymph node showed diffuse infiltration of moderate- to large-sized lymphoid cells with a pleomorphic nucleus and prominent nucleoli (Figure 3) that were CD3+, CD4+, CD5+, CD8-, CD20-, and CD21- on immunohistochemistry (Figure 4).
Tumor cells were CD3+ (a), CD4+ (b), CD5+ (c), CD8- (d), CD 20- (e), and CD21- (f) on immunohistochemistry.
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fig4
A biopsy obtained from the right inguinal lymph node showed diffuse infiltration of moderate- to large-sized lymphoid cells with a pleomorphic nucleus and prominent nucleoli (Figure 3) that were CD3+, CD4+, CD5+, CD8-, CD20-, and CD21- on immunohistochemistry (Figure 4).
Southern blot analysis of HTLV-1 provirus DNA depicted two bands (red arrows) in after BamH-I digestion and two bands (red arrows) after Hind III digestion. 1: BamH-I; 2: EcoR-V; 3: Hind III.
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fig5
Two monoclonal bands for HTLV-1 provirus DNA were observed in lymph node specimens by Southern blot hybridization analysis (Figure 5).
Clinical course of the patient. Abbreviations: PSL: prednisolone; LDH: lactate dehydrogenase; sIL-2R: soluble interleukin-2 receptor.
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fig6
The clinical course of the patient is summarized in Figure 6.