PMC5244775_01
Appearance of the patient. Note the swelling of the parotid and supraclavicular lymph node enlargement.
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On physical examination we found bilateral cervical and right supraclavicular adenopathy accompanied by an enlargement of the two parotid glands (Fig. 1).
(A) Medium-power (magnification, x10) stained with the Papanicolaou technique. Hemorrhagic and lymphocytic background of chronic non-specific lymphadenitis, with large macrophages, with abundant cytoplasm and numerous lymphocytes are observed inside. (B) At higher magnification (magnification, x40) histiocytes with abundant clear or eosinophilic cytoplasm filled with many intact lymphocytes and plasma cells.
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The cytoplasm of these histiocytes has numerous intact lymphocytes and plasma cells (Figs. 2 and 3).
Same characteristics as Fig. 2, but evaluated with the Diff-Quik stain. [(A) Magnification, x10; and (B) magnification, x40].
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The cytoplasm of these histiocytes has numerous intact lymphocytes and plasma cells (Figs. 2 and 3).
Cellular block with hematoxylin and eosin technique at medium power (magnification, x10). Fragment of a lymph node with important sinusoidal dilatation, note the histiocytes lining the sinuses. Many of the histiocytes have intact lymphocytes within their cytoplasm an important diagnostic feature known as emperipolesis.
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The sinuses are occupied by numerous histiocytes with a vesicular nucleus and abundant clear cytoplasm with phagocytized intact lymphocytes, known as 'emperopolesis' (Fig. 4).