PMC4821138_01
Slit-lamp biomicroscopy image of the right eye. Adenoviral keratoconjunctivitis-related SEIs in the central part of the cornea.
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F1
Slit-lamp biomicroscopy revealed mild conjunctival hyperemia, several centrally located corneal SEIs (fig. 1), and superficial punctate epitheliopathy in the right eye.
IVCM image of the right eye. Subepithelial Langerhans cells with characteristic pseudopods (depth: 41 microm).
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F2
Langerhans cells with typical pseudopods were detected at the subepithelial nerve plexus level of the corneas of both eyes, predominantly in the right eye (fig. 2).
Slit-lamp biomicroscopy image of the right eye after the use of 0.05% CsA nanoemulsion formulation for 1 month. SEIs appear less active.
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F3
At the 1-month visit following initiation of the nanoemulsion formulation, her symptoms improved, SEIs appeared less active at slit-lamp biomicroscopy, and there was no corneal staining (fig. 3).
IVCM image of the right eye. No visible subepithelial Langerhans cells are present after 1 month of treatment with the 0.05% nanoemulsion formulation (depth: 40 microm).
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F4
IVCM did not reveal Langerhans cells anymore (fig. 4).