PMC7306531_01
Histopathology slide showing: A) NET invading the submucosa (Hematoxylin-eosin staining, 4x); B) positive result for chromogranin A in neoplastic cells (the nuclei are blue and cytoplasm was brown) (black arrows); C) positive brown-stained cytoplasm for synaptophysin in neoplastic cells (white arrows).
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The histopathology results on August 29th, 2018, showed neuroendocrine carcinoma with a near incision edge; all lymph node specimens were tumor-free (Fig. 1).
PMC7306531_02
Intraoperative findings: A) showing the descending colon mass (yellow arrow); B) and C) left hemicolectomy with end-to-end anastomosis; D) gross photomicrograph of left hemicolectomy specimen showing a large ulcerated mass/growth around 7 x 6 x 5 cm infiltrating the serosa (blue arrow).
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Left hemicolectomy was performed with end-to-end anastomosis (see Fig. 2).
Preoperative MSCT scan with contrast shows large (7 cm) mass in descending colon tumor (yellow arrow).
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On March 23rd, 2018, prior to surgery, patient came to outpatient department in tertiary hospital with abdominal distention then an abdominal CT scan with contrast had been conducted that showed descending colon tumors (Fig. 3).
Histopathology slide showing: A) NEC infiltrating the submucosa (HE 4x); B) positive result for Chromogranin A in neoplastic cells (the nuclei are blue and the cytoplasm was brown) (blue arrows); C) positive result for the brown-stained cytoplasm for synaptophysin in neoplastic cells (black arrows).
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The pathology report showed a malignant tumor, which showed neuroendocrine carcinoma (Fig. 4).
Surveillance MSCT scan with contrast shows hepatomegaly accompanied with right hepatic lobe lesion (yellow arrow).
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On November 15th, 2018, a whole abdominal MSCT was performed with the impression of minimal ascites and hepatomegaly accompanied with right hepatic lobe lesions (suggestive of metastatic tumors), as well circular thickening of descending colon (suggestive of descending colon tumors) (Fig. 5).