PMC88995_01
Sagittal section of the fetal trunk. Note the hypoplastic thorax (thin arrows) and abdomen (thick arrows).
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F1
Microcephaly, flat forehead, micrognathia, generalized edema of the skin, hypoplastic chest (Figure 1), excessive soft tissue deposition of hands and feet (Figure 2), and joint contractures (Figure 3) were detected.
Excessive soft tissue deposition in the foot.
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F2
Microcephaly, flat forehead, micrognathia, generalized edema of the skin, hypoplastic chest (Figure 1), excessive soft tissue deposition of hands and feet (Figure 2), and joint contractures (Figure 3) were detected.
Flexion contractures of the lower limb (arrow: knee).
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F3
Microcephaly, flat forehead, micrognathia, generalized edema of the skin, hypoplastic chest (Figure 1), excessive soft tissue deposition of hands and feet (Figure 2), and joint contractures (Figure 3) were detected.
Photograph of the neonate with the Neu-Laxova syndrome. Note the micrognathia, absent eyelids, scaly skin, ichtyosis and edema of the hands and feet.
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F4
On postmortem examination of the neonate microcephaly, sloping forehead, ocular hypertelorism, protruding eyes with absent lids, micrognathia, short neck, ichtyosis, scaling edematous skin, excessive edema of hands and feet, flexion contractures, undescended testes were detected (Figure 4).
X-ray film of the newborn.
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F5
An x-ray film of the infant revealed microcephaly (Figure 5), and a S-shaped spine.