PMC4025149_01
Erythrodermia on the shoulders; confluent large salmon-colored plaques with mild induration and fine scales on the upper trunk, and discrete small circular or oval lesions along the cleavage lines on the lower trunk of the patient.
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F1
He also showed plaques over his forearms and tibiae (fig. 1).
Mild hyperkeratosis and focal epidermal parakeratosis, mild spongiosis, extensive intracellular edema and focal lymphocytic exocytosis, moderate inflammatory infiltrate from the lymphocytes and histiocytes in his upper dermis and few polymorphonuclear cells perivascularly. Immunohistochemistry showed an intracellular accumulation of HHV-6 (brown stain).
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F2
Immunohistochemistry was positive for an intracellular accumulation of both HHV-6 and HHV-7 (fig. 2).