PMC3161667_01
Multiple skin lesions on the neck, trunk and upper arms, consisting of infiltrated deep red violaceus nodules measuring 1-1,5 cm.
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A 42-year-old man presented with multiple skin lesions on the neck, trunk and upper arms, consisting in infiltrated deep red violaceus nodules measuring 1-1,5 cm (Fig. 1).
(a) Diffuse infiltrate sparing the epidermis mainly composed of small lymphocytes. (b) The same Figure:higher magnification.
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Histopathological examination showed a diffuse infiltrate sparing the epidermis (Fig. 2).
Small CD20+ B cells.
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The central area infiltrate contains mainly small CD20+ (Fig. 3) and CD45RA+ B cells.
CD10 antigen stain.
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Staining for Bcl-6, CD10 (Fig. 4), CD21 and CD45RA were positive.
The skin lesions disappeared leaving a slight hyperpigmentation.
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Over a seven years period, we noticed a progressively disappearance of the skin lesions, leaving only a slight hyperpigmantation (Fig. 5).