PMC3059558_01
A. Computed tomography of the lung; B. Positron emission tomography.
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F1
Positron emission tomography (PET)-CT confirmed that the lesion was fluorodeoxyglucose (FDG)-avid with no other sites of FDG avidity (Figure 1).
A. Lung with left upper lobe adenocarcinoma (hematoxylin and eosin); B. Sigmoid polyp with high grade dysplasia (hematoxylin and eosin).
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F2
TTF-1, while the usual markers for a primary colorectal adenocarcinoma are CK20 and CDX-2. The patient underwent a video-assisted thoracoscopic lobectomy and mediastinal lymphadenectomy revealing a 3.8cm adenocarcinoma with the same histologic (Figure 2A) and immunophenotype (Figure 3) as the previous biopsy. Seven years prior to the discovery of the lung mass she had a 2cm sigmoid adenoma with areas of high grade dysplasia (Figure 2B) and carcinoma in situ resected endoscopically in a piecemeal fashion.
Immunohistochemical profile of the resected tumor. A: CK7; B: CK20; C: TTF-1; D: CDX-2.
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F3
TTF-1, while the usual markers for a primary colorectal adenocarcinoma are CK20 and CDX-2. The patient underwent a video-assisted thoracoscopic lobectomy and mediastinal lymphadenectomy revealing a 3.8cm adenocarcinoma with the same histologic (Figure 2A) and immunophenotype (Figure 3) as the previous biopsy.