PMC5875406_01
Nonreacting, dilated pupil (A) and multifocal exudative retinal detachment with macular edema (B) in the right eye.
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The right eye pupil was 8 mm in size, dilated, and nonreacting (Figure 1A), and the retina had exudative retinal detachment around the disc with macular edema (Figure 1B).
Left eye with circumciliary congestion, edematous cornea, and fibrinous exudates with hyphema in anterior chamber.
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The anterior chamber was filled with fibrinous exudates and hyphema (Figure 2).
Subcutaneous ulcerated nodule in the scalp (A) and papulomacular rashes and nodules on the arm and trunk (B).
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On systemic examination, there were multiple papulonodular rashes over the face (Figure 3A) and trunk with a subcutaneous ulcerated nodule in the scalp, arm, and back of trunk (Figure 3B).
Histopathological examination of skin showing dense cellular infiltrate composed of histiocytes, lymphocytes, and occasional eosinophils.. Note: Arrow: the histiocytes have scanty cytoplasm, a nucleus with coffee bean appearance and prominent nucleoli with mitosis.
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The histiocytes have scanty cytoplasm, a nucleus with coffee bean appearance and prominent nucleoli with mitosis (Figure 4) and were positive for histiocytic S 100, suggestive of LCH.