PMC9286925_01
Liver portal triad is expanded by lymphocytes, eosinophils, and noncaseating granulomatous inflammation. H&E stain of liver tissue. No interface hepatitis or proliferating bile ductules. Original magnification, 400x.
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fig1
This showed portal triad inflammation involving lymphocytes, eosinophils, and granulomatous inflammation (Figure 1), as well as rare lobular microgranulomata (Figure 2).
Lobular microgranuloma in the liver. H&E stain of liver tissue. Original magnification, 400x.
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fig2
This showed portal triad inflammation involving lymphocytes, eosinophils, and granulomatous inflammation (Figure 1), as well as rare lobular microgranulomata (Figure 2).
Immunohistochemical staining of CD68-positive macrophages/Kupffer cells (brown stain) in the liver. An excessive number of macrophages are located in sinusoids.
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fig3
Liver sinusoids had excessive numbers of Kupffer cells (Figure 3) and T-lymphocytes (Figure 4).
Immunohistochemical staining of CD3-positive T-lymphocytes (brown stain) in the liver. An excessive number of T-lymphocytes are in sinusoids.
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Liver sinusoids had excessive numbers of Kupffer cells (Figure 3) and T-lymphocytes (Figure 4).
Sinusoidal histiocytic hemophagocytosis. H&E stain of liver tissue. Examples of mature red cells within histiocyte cytoplasm as well as probable degenerate neutrophils within histiocytes are circled. Original magnification, 400x.
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fig5
Occasional benign appearing histiocytes/Kupffer cells had findings of hemophagocytosis of red blood cells and probable leukocytes (Figure 5).