PMC6547021_01
Clinical history of the patient from her first hospital admission to date. Each bar represents a hospitalization, detailing its duration (days) and highest concentration of creatine kinase (CK) reached. Kidney Symbol: renal failure.
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F1
Three episodes of rhabdomyolysis were accompanied by renal failure (Figure 1).
Fat oxidation capacity in exercise in a healthy person vs. a patient with VLCADD. Muscle discomfort during exercise appears at intensities close to FATMAX (marked in red), modified from (10). High-intensity interval training was always at high intensity (in which the demand for fat oxidation is practically null). Completed only 40 s of the last step.
fphys-10-00650-g002.jpg
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F2
We chose this type of training to maintain a high demand for glycolysis during exercise and, therefore, avoid the dependence of lipolysis on energy production (at the highest possible intensity, well above FATMAX) (Figure 2).