PMC9234115_01
PMC9234115_02
PMC9234115_03
Timeline of medication and laboratory data over the course of the study period. (A-C) Timeline of medication and laboratory data for RP13 (A), RP15 (B), and RP16 (C) over the course of the study period. Month 0 represents the time of TCZ initiation. ANC, absolute neutrophil count; CRP, C-reactive protein; Hb, hemoglobin; IV, intravenous injection; MCV, mean corpuscular volume; PSL, prednisolone; RBC, red blood cell count; SC, subcutaneous injection; TCZ, tocilizumab; WBC, white blood cell count.
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f1
Although he has experienced some unresolved symptoms, including arthritis, skin rash, and transfusion dependence, the skin rash was manageable with topical treatment, and the red blood cell transfusion frequency had decreased from once every 2 weeks to approximately once every 6 weeks ( Figure 1 ).