PMC6800898_01
Aminotransferase measurements preceding, during, and following drug-induced liver injury. Measurements are expressed in international units per liter. AST peak was 950 on 03/02/2019; ALT peak was 2,007 on 03/07/2019. ALT: alanine aminotransferase; AST: aspartate aminotransferase; DILI: drug-induced liver injury.
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fig1
Figure 1 summarizes the patient's AST/ALT trends from his baseline prior to the liver injury to his gradual return to normal limits a few weeks later. From a treatment standpoint, a subsequent positron emission tomography (PET)/computed tomography (CT) scan from April 2019 demonstrated tumoral response with decreased fluorodeoxyglucose (FDG) uptake in several previously noted soft tissue and bony metastases.