PMC4631292_01
The figures illustrate images from the videostroboscopic examination of the larynx. A tumour narrowing the laryngeal lumen is visible
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No infiltration of other laryngeal structures or other anomalies was observed (Fig. 1 A, B).
The figures present CT images of the larynx in horizontal plane with indicated tumour size
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Microscopic image of osteosarcoma. Analysis of the slides was performed using 200x total magnification (20x objective with 10x oculars). A - the arrows highlight osteosarcoma invasion into cartilage; B - the arrows highlight osteosarcoma invasion into surrounding muscles; C - areas of ossification and deposition of osteoid material; D - positive immunohistochemical staining for vimentin
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Extensive areas of ossification and deposition of osteoid material with bone formation were observed in different tumour parts (Fig. 3A, B, C). Histological examination also revealed extensive invasion into thyroid cartilage (Fig. 3A) and surrounding soft tissues (Fig. 3B). The tumour was positive for vimentin (Fig. 3D), and Ki-67-positive cells index was approximately 5% on average but focally up to 30%.