PMC7779284_01
(A) Chest enhanced CT before treatment: an anterior segment of the right upper lobe with an irregular soft tissue density of approximately 22 mm x 19 mm in shape. (B) Multiple burr shadows on the edges, and multiple enlarged lymph nodes in the right hilum.
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In order to assess the quality of his lung, he underwent a computed tomography (CT) scan and found that the density of the irregular soft tissue in the anterior segment of the right upper lung lobe was about 22mmx19mm, and there were multiple burr shadows on the edges (Figure 1).
Right lung tumor biopsy specimen: malignant tumor of epithelial origin, prone to large cell carcinoma. Immunohistochemistry: CK (+), Ki67 (60% +), P63 individual cells (+), TTF-1 (-), Syn (-), CD56 (-), CgA (-).
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Then, the patient underwent a fine needle aspiration biopsy of the right lung mass, the pathologic diagnosis was large cell carcinoma (Figure 2).
Chest enhanced CT after neoadjuvant immunotherapy: (A) The area of the anterior segment of the right upper lobe of the lung was significantly smaller than that of the anterior, with a maximum cross-section of about 11 mm x 7 mm. (B) The mediastinal and right hilar swollen lymph nodes were smaller than before, and the adjacent pulmonary vessels were more compressed Before remission.
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The enlarged lymph nodes in the mediastinum and right hilar were smaller than before, and the compression of the adjacent pulmonary vessels was relieved (Figure 3).