PMC5109566_01
Computed tomography of the abdomen. An enhanced pancreatic tumor with metastasis to the para-aortic lymph nodes was demonstrated. A) Beginning of December, 2009. B) End of September, 2011.
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A mass measuring 6 cm in diameter was noted in her pancreas (Fig. 1A). Computed tomography (CT) of the abdomen revealed a progressive enlargement of the pancreatic tumor with metastases to the para-aortic lymph nodes (Fig. 1B). No liver metastasis was observed, but the decrease in visceral and subcutaneous and fat area was apparent as compared to the previous CT (Fig. 1).
Pathological examination of the pancreatic tumor. A) Well-differentiated neuroendocrine tumor (Hematoxylin and Eosin staining). B) The percentage of Ki67 positive cells was 11.5%. C) Positive immunostaining for ACTH. D) Positive immunostaining for GHRH. ACTH: adrenocorticotropic hormone, GHRH: growth hormone-releasing hormone
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A biopsy of the pancreas was performed, and the diagnosis of a well-differentiated neuroendocrine tumor was made (Fig. 2A). The percentage of Ki67-positive cells was 11.5% (Fig. 2B), and these findings were consistent with the diagnosis of NET G2.