PMC5095519_01
(a) Eight years before surgical excision (17 x 12 x 14 mm). (b) Four years before surgical excision (28 x 18 x 30 mm). (c) Preoperative (60 x 20 x 35 mm).
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F0001
Computed tomography revealed a mass measuring 28 x 18 x 30 mm in the subcutaneous tissue (Figure 1(b)). We found her previous abdominal computed tomography results and confirmed that the mass had already existed 8 years previously, but it had been much smaller (17 x 12 x 14 mm) (Figure 1).
(a) Preoperative appearance. (b) The excised mass with indurated subcutaneous fat.
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F0002
We excised the mass with indurated subcutaneous fat (Figure 2).
(a,b) The subcutaneous tissue was degenerated broadly (Haematoxylin and eosin staining). (c) Extensive amyloid deposition in the subcutaneous tissue (arrow) (Congo red staining). (d) No evidence of vascular involvement (arrow: subcutaneous artery without amyloid deposition) (Congo red staining).
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F0003
Amyloid-AA, kappa-chain and lambda-chain were not detected immunohistochemically (Figure 3).