PMC4475784_01
Axial T2/FLAIR images obtained four months apart at the level of the temporal lobes (A. initial, B. follow-up) and insula (C. initial, D. follow-up). The somewhat increased signal bilaterally in the mesial temporal structures and insula was present, but not definitively abnormal, and did not significantly change over time.
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However, the appearance of these areas did not significantly change over time despite his progressively worsening symptoms (Fig. 1).
A. and D. Axial T2/FLAIR MRI at the level of the temporal lobes and insula, respectively, with possible mesial temporal and insular hyperintensities; C. and F. FDG-PET images at these levels showing bitemporal and bilateral insular hypometabolism; B. and E. Coregistered MRI and PET at these levels, showing where the areas of hypometabolism align with the detailed neuroanatomy.
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Brain PET/MRI revealed bitemporal and bilateral insular hypometabolism (Fig. 2).