PMC6563401_01
(A) Hematoxylin and eosin staining at 20x (inset at 40x showing mononuclear infiltrate within the intimal layer). (B) EVG staining at 20x (inset at 40x showing disruption of elastin layers). (C) CD3 staining at 20x (inset at 40x showing lymphocytes within the intimal layer). (D) CD163 staining at 20x (inset at 40x showing histocytes within the intimal layer).. Pathology section: Sections in the figure show a vessel with moderate intimal hyperplasia with inflammatory cells present within the intimal layer. An elastin stain was performed showing a disruption of the elastic layer of the intimal surface with fibrosis. CD3 and CD163 were performed and revealed the presence of lymphoid and histiocytes. This may represent the previous arteritis that occurred.
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He had temporal artery biopsy of both sides, of which biopsy of the right side showed mild to moderate intimal hyperplasia, partial disruption of internal elastic lamina with fibrosis, and minimal lymphocytic and histolytic infiltrates, which was consistent with GCA (Figure 1).