PMC5596258_01
Computed tomographic scans, showing (a) free air at the liver surface and the gastric cardia with fluid collection (white arrows) and (b, c) a solid mass within the pelvis, measuring approximately 14 cm x 7 cm, with some air (short arrows) and internal liquid (long arrows).
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C-reactive protein concentration of 6.39 mg/dL. Computed tomography (CT) scan revealed a solid mass measuring approximately 14 cm x 7 cm within the pelvis, and free air around the gastric cardia and perihepatic fluid (Fig. 1a-c).
Intraoperative photograph, showing an approximately 14 cm perforated tumor with a hole measuring approximately 5 mm (white arrow) in the jejunum. The tumor was located 100 cm from Treitz's ligament.
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Treitz's ligament (Fig. 2). The tumor was perforated, with a hole measuring approximately 5 mm.
a, b. Isolated specimens arising from the jejunal wall, with a small perforation of the intestinal tract (white arrow). c. The cut surface of the solid parenchyma, revealing a central necrotic cavity with a fistula to the lumen of the jejunum.
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The solid parenchyma contained an area central necrosis with a fistula to the lumen of the jejunum. (Fig. 3) Hematoxylin and eosin staining showed proliferation of spindle-shaped cells, and immunohistochemical staining showed that the tumor was positive for c-kit and CD34, with approximately 10% of the tumor cells positive for nuclear expression of the proliferation-associated antigen Ki-67. (Fig. 4 ) The patient was diagnosed with a high-risk GIST of the jejunum.
a. Microscopic examination (hematoxylin-eosin staining, original magnification: x100) showing proliferation of spindle-shaped cells. b, c. Immunohistochemical staining, showing that tumor cells were positive for (b) c-kit and (c) CD34. d. The cell proliferation index (Ki67) was approximately 10%.
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The solid parenchyma contained an area central necrosis with a fistula to the lumen of the jejunum. (Fig. 3) Hematoxylin and eosin staining showed proliferation of spindle-shaped cells, and immunohistochemical staining showed that the tumor was positive for c-kit and CD34, with approximately 10% of the tumor cells positive for nuclear expression of the proliferation-associated antigen Ki-67. (Fig. 4 ) The patient was diagnosed with a high-risk GIST of the jejunum.