PMC4582513_01
Rhinophyma in tuberous sclerosis complex patient at the time of admission, profile (A) and en face (B) photographs of the nose. Debulking procedure of the rhinophyma exposes fibrous tissues with enlarged sebaceous glands (C). Electrosurgical remodeling of the nose's shape (D) and uneventful wound closure during secondary re-epithelialization of the nose (20 days after surgery (E)). Six years later (F, G) the shape of the nose has remained unchanged but a slight and partial recurrence of angiofibroma is visible.
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F1
The rhinophyma was removed in layers using an electrosurgical needle (Figure 1C (Fig. 1)). Uneventful healing was achieved by secondary intention (Figure 1D and E (Fig. 1)).In addition, a hyperplastic region of the frontal skin graft was excised, primarily closed and the excised specimen was prepared for histological investigation. On this occasion, the stable contouring of the nose was documented (Figure 1F and G (Fig. 1)).
Dermal histopathology presenting as groups of dilated thin walled vessels in fibrous tissue and hyperproliferative sebaceous glands, H&E stain.
IPRS-03-12-g-002.jpg
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F2
Enlarged capillaries compatible with angiofibroma predominated in the subepidermal layers (Figure 2 (Fig. 2)).