PMC3921808_01
Computed Tomography scan showing multiple lesions (white arrows) within urinary bladder and a large bladder diverticulum (black arrow).
CEJU-65-00225-g001.jpg
PMC3921808_01_CEJU-65-00225-g001.jpg
F0001
An 84-year-old gentleman was referred to the Urology Department at Bedford Hospital with a computed tomography (CT) scan revealing multiple polypoidal lesions in the urinary bladder (Fig. 1) and bilateral pulmonary metastases.
Cystoscopic finding of a pigmented bladder metastasis.
CEJU-65-00225-g002.jpg
PMC3921808_01_CEJU-65-00225-g002.jpg
F0002
During a flexible cystoscopy performed in September 2011, multiple pigmented lesions were identified within the bladder (Figs. 2 and 3).
Cystoscopic finding of multiple small, pigmented bladder metastases.
CEJU-65-00225-g003.jpg
PMC3921808_01_CEJU-65-00225-g003.jpg
F0003
During a flexible cystoscopy performed in September 2011, multiple pigmented lesions were identified within the bladder (Figs. 2 and 3).
Urine cyto 63X - Malignant melanoma cells with high N:C ratio and cytoplasmic melanin pigment on PAP stained preparation.
CEJU-65-00225-g004.jpg
PMC3921808_01_CEJU-65-00225-g004.jpg
F0004
Urine cytology revealed a number of scattered single cells containing pigment, positive for S100 and HMB45, and negative for Perl's stain for iron (Figs. 4 and 5).
HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).
CEJU-65-00225-g005.jpg
PMC3921808_01_CEJU-65-00225-g005.jpg
F0005
Urine cytology revealed a number of scattered single cells containing pigment, positive for S100 and HMB45, and negative for Perl's stain for iron (Figs. 4 and 5).