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Brain MRI T1-WI axial plane of a patient with ephedrone encephalopathy: symmetrical signal increase in globi pallidi.
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Symmetrical increase in signal intensity on T1-WI in globi pallidi was observed in all our patients (Figure 1).
Brain MRI T1-WI axial plane of a patient with ephedrone encephalopathy at midbrain level: increased signal intensity in cerebral peduncles.
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Lesions of similar nature were reported in midbrain in three patients (Figure 2) and in cerebellar hemispheres in just one(Figure 3).
Brain MRI T1-WI sagittal plane of a patient with ephedrone encephalopathy: moderate signal intensity increase in cerebellar hemisphere white matter and significant signal intensity increase in globus pallidus.
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Lesions of similar nature were reported in midbrain in three patients (Figure 2) and in cerebellar hemispheres in just one(Figure 3).
Non-enchanced brain MRI T1-WI medial sagittal plane of a patient with ephedrone encephalopathy: significant increase of signal intensity in pituitary gland frontal lobe. In healthy individuals the lobe is isointense with cerebral gray matter.
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High signal of pituitary gland frontal lobe on non-enchanced T1-WI was observed in a single patient (Figure 4).
Brain MRI T2-WI axial plane of a patient with ephedrone encephalopathy: symmetrically low intensity signal in globi pallidi.
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Additionally, slight signal intensity decrease on T2-WI and FLAIR was observed subjectively in globi pallidi (Figure 5).
Initial brain MRI T1-WI axial plane of a patient with ephedrone encephalopathy: symmetrically high intensity signal in globi pallidi (globus pallidus to frontal lobe white matter signal intensity ratio is ca. 152%).
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Reduction of signal intensity in globi pallidi on T1-WI was observed in all patients (Figures 6 and 7).
Follow-up brain MRI T1-WI axial plane of a patient with ephedrone encephalopathy obtained 7 months later: reduction of signal intensity in globi pallidi in comparison to the initial image in Figure 6 (globus pallidus to frontal lobe white matter signal intensity ratio is 105%; signal remains moderately increased compared to healthy individuals).
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Reduction of signal intensity in globi pallidi on T1-WI was observed in all patients (Figures 6 and 7).
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