PMC3656891_01
Fundus color photograph (A) of our patient with systemic lupus erythematosus, showing unilateral central retinal vein occlusion. Superficial and deep intraretinal hemorrhages are scattered throughout the retina. Fluorescein angiogram (B) shows a pattern resembling cystoid macular edema (CME) without ischemia of the macula or the peripheral retina. Optical coherence tomography (C) reveals retinal swelling and CME. Fundus-monitored microperimetry with the MP-1 system (D) indicates a cessation of foveal sensitivity.
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Superficial and deep intraretinal hemorrhages were scattered throughout the retina, suggesting that the patient had CRVO (Figure 1A). Fluorescein angiography showed CME without ischemia of the macular region or peripheral retina (Figure 1B). Optical coherence tomography (OCT) identified retinal swelling and CME (Figure 1C). Fundus-monitored microperimetry with the MP-1 system (Nidek, Gamagori, Japan) revealed a cessation of foveal sensitivity (Figure 1D).
Optical coherence tomography (OCT) (A) shows marked improvement of retinal swelling and cystoid macular edema (CME) at 2 weeks after the first intravitreous injection of bevacizumab. OCT (B) reveals the recurrence of macular edema at 3 months after intravitreous anti-vascular endothelial growth factor (VEGF) therapy. OCT (C) displays marked improvement of retinal swelling and CME at 1 week after the second intravitreous injection of bevacizumab. Fundus-monitored microperimetry with the MP-1 system (D) demonstrates improvement of foveal sensitivity.
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OCT showed marked alleviation of retinal swelling and CME (Figure 2A). However, recurrence of edema was noted after 3 months (Figure 2B) and VA of the left eye decreased to 20/50. The VA of the left eye improved to 20/20 again, while OCT showed marked alleviation of retinal swelling and CME at one week after the second intravitreous injection (Figure 2C). In addition, there was improvement of foveal sensitivity (Figure 2D).