PMC3018960_01
Clusters of plasma cells can be seen throughout this view of the aspirate - P.N. case (BM -MGG, objective 
20X)
JMedLife-01-74-g001.jpg
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F1
Dot-plot histograms: plasma cells (purple) positive for CD 38, CD 138, CD 56 and negative for CD 19 (BD 
Facs-Calibur, Software CellQuest version 3.3) -  P.N. case.
JMedLife-01-74-g002.jpg
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F2
Dot -  plot histograms: plasma cells (purple) positive for CD 38, CD 138, CD 56 and negative for CD 19 (BD 
Facs -  Calibur, Software CellQuest version 3.3) -  P.N. case.
JMedLife-01-74-g003.jpg
PMC3018960_01_JMedLife-01-74-g003.jpg
F3
Clusters of plasma cells with azurophilic granules (MO - MGG, 100x 
objective) -P.N. case
JMedLife-01-74-g004.jpg
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F4
The particular aspect of this case resides in the morphological features of the myeloma plasma cells  (Fig 4 to Fig 7).
Plasma cells with numerous azurophilic granules, some granules have foamy aspect (MO - MGG, 
100x objective) - P.N. case
JMedLife-01-74-g007.jpg
PMC3018960_01_JMedLife-01-74-g007.jpg
F7
The particular aspect of this case resides in the morphological features of the myeloma plasma cells  (Fig 4 to Fig 7).
Skull x - ray showing multiple lytic areas - P.N. case
JMedLife-01-74-g008.jpg
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F8
The investigations were completed with X - rays of the skull which showed multiple lytic cranial lesions and diffuse osteoporosis  (Fig 8).
Spinal MRI scan - compression fracture of T12, L1, L2 with collapsed plateau - P.N. case
JMedLife-01-74-g009.jpg
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F9
Spinal MRI scan identified of compression fracture of T12, L1, L2 with diffuse  osteoporosis (Fig 9).