PMC3603648_01
PET in a breast cancer patient shows abnormal FDG uptake.
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TruePoint 2008A. CT data was acquired without contrast enhancement and using the following parameters: 130 kV; 60 mAs; pitch 1.5; and slice thickness, 5 mm. The PET CT scan revealed a left breast mass with a size of 27 x 17 mm with a maximum standard uptake value (SUV) of 10,13 and six left axillary lymph nodes measuring up to 17 x 12 mm in size showed intense FDG avidity with SUV value of 8,10 (Figure 1).
CT (right), PET (middle left), and PET CT (left) transaxial images show intense FDG uptake of mediastinal and axillary lymph nodes and left breast mass.
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In addition, right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes with SUV value of 8,16 were revealed (Figure 2).
Noncaseating granulomas in lymphoid tissue (H-E, 10x).
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Pathology was reported as granulomatous lymphadenitis, auramine-rhodamine (A-R) and Ehrlich-Ziehl-Neelsen (EZN) stainings were negative, no Schaumann or asteroid bodies were observed, and examination of histological sections revealed epithelioid histiocytes, lymphocytes, and a few Langhans-type giant cells with noncaseating granulomas (Figures 3 and 4).
Granulomas showing epithelioid hystiocytes and lymphocytes (H-E, 40x).
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fig4
Pathology was reported as granulomatous lymphadenitis, auramine-rhodamine (A-R) and Ehrlich-Ziehl-Neelsen (EZN) stainings were negative, no Schaumann or asteroid bodies were observed, and examination of histological sections revealed epithelioid histiocytes, lymphocytes, and a few Langhans-type giant cells with noncaseating granulomas (Figures 3 and 4).