PMC5686041_01
Lower magnification of the encapsulated tongue mass (20X; H&E).
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PMC5686041_01_gr1.jpg
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The hematoxylin and eosin stained sections of the formalin fixed and paraffin embedded tongue mass show an encapsulated (Fig. 1), nodular lesion composed of rounded to ovoid and polygonal cells with eosinophilic and "frothy" cytoplasm.
The tumor is composed of rounded of ovoid cells with eosinophilic, somewhat frothy, cytoplasm with scattered cells having intracytoplasmic vacuoles (200X; H&E).
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PMC5686041_01_gr2.jpg
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Some cells showed intracytoplasmic vacuoles (Fig. 2).
Although focal, the lesion demonstrated net-like growth pattern with slit-like spaces (200X; H&E).
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PMC5686041_01_gr3.jpg
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Focally, the lesion demonstrated net-like growth pattern with slit-like spaces (Fig. 3).
Multinucleated giant tumor cells were also evident although no calcifications were noted in our case (100X; H&E).
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PMC5686041_01_gr4.jpg
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Multinucleated tumor giant cells were seen (Fig. 4) although the tumor lacked in calcifications.
Neural immunohistochemical markers like neuron-specific-enolase (NSE) were focally positive (Inset: positive s100 protein marker).
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PMC5686041_01_gr5.jpg
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