PMC8010237_01
MRI of the brain revealed subtle increased signal intensity in bilateral hippocampal on FLAIR sequences (A). CT scan of the abdomen indicated a space-occupying lesion in right-side ovarian, later pathologically identified as mature ovarian cystic teratoma (B).
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F1
Head MRI examination detected subtle increased signal intensity in bilateral hippocampal on FLAIR sequences (Figure 1A). With the suspicion of ovarian teratoma in our patient, abdominal CT was performed on hospital day 10, which indicated a space-occupying lesion (2.0 x 3.0 cm) in the right-side ovary (Figure 1B).
The pure tone audiogram on admission indicated bilateral serious sensorineural hearing loss, predominantly in higher frequencies (A,B), and achieved significant improvement 3 days before discharge (C,D).
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F2
The otoscopic examination showed no evidence of the external auditory canal and tympanic membrane abnormality, yet pure tone audiogram indicated bilateral serious sensorineural hearing loss, predominantly in higher frequencies (Figure 2). Pure tone audiogram indicated nearly normal hearing in both ears (Figure 2).
Immunohistochemical findings (A,B) and inflammatory response (C,D) in this patient's ovarian teratoma. GFAP (A) and S-100 (B) immunohistochemical staining were positive. Infiltration of scattered CD3 T-cells (C) and CD20 (D) B-cells.
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F3
On hospital day 14, the patient underwent laparoscopic ovarian cystectomy, and a pathological examination revealed a mature ovarian cystic teratoma, containing nervous tissue (Figure 3).
Clinical course of the case.
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F4
The clinical course is summarized in Figure 4.