PMC7652426_01
(A): Low power view of the breast infiltrating ductal carcinoma; NOS showing cords of large malignant cells (arrow) separated by scant stroma; no papillae are detected (H&E x 100). (B): Higher power view of the breast carcinoma; the malignant cells are large with vesicular pleomorphic nuclei, coarse chromatin, with no classic nuclear features of papillary carcinoma; (arrow) the cytoplasm is ample and eosinophilic (H&E x 400).
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figure1
IIB BC (Figure 1). Immunohistochemistry stained strongly positive for oestrogen and progesterone receptors and was negative for human epidermal growth factor receptor-2 (HER-2).
(C): Low power view of the thyroid papillary carcinoma; classic variant with multiple papillary structures having fibrovascular cores (arrow) separated by vascularized stroma (H&E x 100). (D): Higher power view of the thyroid papillary carcinoma; the papillae are lined with a layer of cells showing evident nuclear features with large ground glass overlapped nuclei (arrow) (H&E x 400).
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PMC7652426_01_can-14-1125fig2.jpg
figure2
Focal vascular and extracapsular invasions were present (Figure 2).