PMC3934682_01
Funduscopic findings at the first visit. Funduscopic findings OS revealed a geometric lesion at the RPE level of the interpapillomacular area, contiguous with the slightly hyperemic optic nerve. The lesion was composed of marginal RPE hyperplasia and atrophic RPE in its center. Findings from the right fundus examination were normal.
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F1
Funduscopic findings revealed a geometric lesion at the RPE level of the interpapillomacular area, contiguous with the slightly hyperemic optic nerve (fig. 1).
Twenty-three months after the first visit, the enlargement of the lesion and the development of subfoveal CNV were observed (upper left: funduscopic findings, lower left: OCT findings). FA findings revealed dye leakage from the optic nerve and CNV (upper right: early-phase image, upper left: late-phase image).
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F2
Funduscopic examination showed enlargement of the lesion and development of subfoveal CNV (fig. 2). FA findings revealed hypofluorescence from RPE hyperplasia, hyperfluorescence from RPE atrophy and dye leakage from the optic nerve and CNV (fig. 2). Optical coherence tomography (OCT) revealed type 2 CNV, but the exudative change was not obvious (fig. 2).
Seven years after the first visit, the geometric lesion and CNV kept expanding steadily and new CNV developed at the inferior retina (upper: panoramic funduscopic findings, bottom: panoramic FA findings).
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F3
Seven years after the first visit, the geometric lesion and the CNV kept expanding steadily, and new CNV developed at the inferior retina (fig. 3).