PMC8437654_01
Thyroid ultrasound: linear probe and high frequency. Right lobe: hypoechoic polylobular nodule with intense intranodular vascularisation classified as EU-TIRADS 5.
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fig1
Ultrasound (Figure 1) revealed a large hypoechoic polylobular nodule in the right lobe with a dense central vascularisation, classified as EU-TIRADS 5.
Hematoxylin-eosin staining showing large clear cells. A thin fibrovascular network is shown (arrow). Cells have an eosinophilic foamy vacuolated cytoplasm.
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PMC8437654_01_CRIE2021-2735256.002.jpg
fig2
The histopathological examination showed large clear cells positive for CD10, vimentin, CK19, and PAX 8 with lymphatic and venous metastasis (Figure 2).