PMC6930727_01
Fundus color photo of (a) right eye; (b) left eye. Subtle pigmentary changes temporal to the macula (arrow).
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Posterior segment examination revealed subtle pigmentary changes temporal to the macula in both eyes (Figure 1). One area of ONL in proximity to the excavation demonstrated hyperreflectivity, similar to the reflectivity of the adjacent outer plexiform layer (OPL) (Figure 2 OD1 and OS2).
EDI-OCT scan of posterior pole of right eye (OD) and left eye (OS). OD1: Multiple focal choroidal excavations were showed in one horizontal scan. The outer nuclear layers (ONLs) conformed to retinal pigment epithelium (RPE) alterations within the excavation. And the RPE layer followed the contour of the choroidal excavation. There is no RPE detachment and no separation between the photoreceptor and the RPE. One area (arrow) of outer nuclear layers (ONLs) beside the excavation became hyperreflective with a density similar to that of the outer plexiform layer (OPL). OD2: Choriocapillaris in the site of excavation (Arrow) is thinner with adjacent large blood vessels changes comparing to the surrounding choroid. OS1: Multiple FCE without involving the fovea. OS2: Similar hyperreflective ONLs revealed in the left eye beside of the FCE lesion (arrow).
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The OCT-detected multiple FCEs corresponded with the retinal pigmentary changes by infrared fundus photo in OCT (Figure 2). And the outer nuclear layers (ONLs) conformed to the contour of the RPE within the excavation (Figure 2). One area of ONL in proximity to the excavation demonstrated hyperreflectivity, similar to the reflectivity of the adjacent outer plexiform layer (OPL) (Figure 2 OD1 and OS2). Choriocapillaris thinning in the site of excavation was adjacent to large blood vessels as compared with the normal surrounding choroid layers without FCE (Figure 2 OD2).
Autofluorescence photo of (a) right eye and (b) left eye showed irregular hyper and hypofluorescence in the macular area, which suggested some retinal pigment epithelium loss or damage.
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