PMC4361905_01
Brain MRI at baseline (02.05.13; a), after 1 month of treatment with bevacizumab plus vinorelbine at the end of posterior fossa irradiation (05.06.13; b), and after 11.5 months of treatment with bevacizumab plus vinorelbine (15.04.14; c).
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F1
Upon completion of radiotherapy, repeat MRI was performed and confirmed a radiographic response in both the brain and spine (fig. 1). Despite no significant progression of the LM on an MRI scan and continued negative CSF cytology, the patient rapidly deteriorated and died within several weeks (fig. 1).