PMC8579760_01
8 mm exophytic, friable, vascular-appearing papule on the right neck.
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F1
Physical examination of the right neck revealed an 8 mm exophytic, friable, red papule with overlying heme crust (Figure 1).
Hematoxylin-eosin stain of the right neck.
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F2
Histopathologic analysis revealed epidermal spongiosis and acanthosis with a dermal proliferation of capillaries embedded in an edematous, fibromyxoid stroma with numerous lymphocytes and histiocytes (Figure 2).
Warthin-Starry stain of the right neck.
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F3
Warthin-Starry stain revealed scattered coccobacilli, and other special stains (DPAS, Gram and acid-fast) were negative for microorganisms (Figure 3).
Right neck two weeks after initiation of treatment with a hyperpigmented papule at site of previous lesion.
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F4
Within two weeks, he noted resolution of his fevers and malaise as well as near resolution of the lesion on his right neck (Figure 4).