PMC3843912_01
Pustular palmar lesions, associated with erythema and desquamation.
cde-0005-0326-g01.jpg
PMC3843912_01_cde-0005-0326-g01.jpg
F1
Dermatology Ambulatory as an emergency case due to complaints of sudden onset of pustular lesions in the palms and soles (fig. 1, fig. 2), and erythematous-desquamating plaques with pustules in the limbs, chest and dorsum (fig. 3). During anamnesis, we found that the patient had recently begun the use of golimumab, a
Pustules in the center of erythematous-desquamative lesions of the lower limbs.
cde-0005-0326-g03.jpg
PMC3843912_01_cde-0005-0326-g03.jpg
F3
Dermatology Ambulatory as an emergency case due to complaints of sudden onset of pustular lesions in the palms and soles (fig. 1, fig. 2), and erythematous-desquamating plaques with pustules in the limbs, chest and dorsum (fig. 3). During anamnesis, we found that the patient had recently begun the use of golimumab, a
Epidermis with acanthosis and exuberant exocytosis of neutrophils, which in segment configure Kogoj's spongiform pustule; note also dilation of the capillaries of the papillary dermis. HE. x10.
cde-0005-0326-g04.jpg
PMC3843912_01_cde-0005-0326-g04.jpg
F4
Histopathology showed abundant neutrophilic infiltrate (Munro's abscess), acanthosis, presence of Kogoj's spongiform pustule, and dilation of papillary dermal capillaries (fig. 4, fig. 5).