PMC5352719_01
Chest computed tomography showing diffuse ground-glass opacities.
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A chest computed tomography (CT) showed diffuse ground-glass opacification (GGO) (Fig. 1), and a paranasal sinuses CT revealed opacification of the frontal and ethmoidal sinuses (Fig. 2).
A diffuse chronic inflammatory infiltrate with a marked presence of eosinophils (star) is found near the bronchioles.
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An open lung biopsy was performed and demonstrated intense perivascular eosinophilic inflammatory infiltrate (Fig. 3, Fig. 4), confirming the diagnosis of EGPA (Table 1).
Chest computed tomography after induction therapy with glucocorticoids showing improvement of ground-glass opacities.
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The patient received prednisone 40 mg once daily (0.5 mg/kg/day) for four months leading to a resolution of respiratory and systemic symptoms, lungs infiltrates (Fig. 5) and eosinophilia.