PMC9138913_01
Non targeted liver biopsy showing hepatic parenchyma almost entirely replaced by metastatic Merkel cell carcinoma (a) Higher magnifications (b, c) showing tumor cells replacing the hepatic parenchyma. The tumor cells are positive for synaptophysin immunohistochemistry (d) and negative for HSA immunohistochemistry (e).
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F1
The biopsy showed the hepatic parenchyma completely replaced by metastatic Merkle cell carcinoma tumor cells with positive immunohistochemistry (Fig. 1).