PMC7566087_01
Chest CT shows multiple pulmonary patchy infiltrates.
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This was confirmed by computed tomography (CT), raising the suspicion of an underlying opportunistic infection or lymphoproliferative disorder (Fig. 1).
PMC7566087_02
Colonoscopy shows a bulging mass at the ileocecal valve.
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Colonoscopy showed a bulging mass arising from the ileocecal valve, suspicious for a tumoral process from which biopsies were taken (Fig. 2).
18F-FDG PET/CT scan. (A) Maximum intensity projection (MIP) image. (B, C) multiple highly hypermetabolic pulmonary infiltrates. (D, E) hypermetabolic tumoral mass (arrow) at the ileocecal valve and hypermetabolic abdominal adenopathies.
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PET/CT showed multiple mesenteric lymph nodes and a tumoral mass in the terminal ileum at the ileocecal valve and one in the descending colon (Fig. 3).
Biopsy specimens of the ileocecal mass. (A-C) Hematoxylin and eosin staining shows inflammation with lymphocytes and histocytes. (A: 25 x H&E, B: 100 x H&E, C: 400 x H&E. (D) Grocott's methenamine silver stain shows yeast-like forms.
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In the cytoplasm of the histocytes rounded organisms were identified (Fig. 4).