PMC3526909_01
Bilateral yellow conjunctival lesions from necrobiotic xanthogranuloma and chronic lymphocytic leukemia.
opth-6-2045f1.jpg
PMC3526909_01_opth-6-2045f1.jpg
f1-opth-6-2045
Bilateral yellow conjunctival lesions were seen temporally in the bulbar conjunctiva (Figure 1).
Optical coherence tomography demonstrating subretinal fluid in the left eye.
opth-6-2045f2.jpg
PMC3526909_01_opth-6-2045f2.jpg
f2-opth-6-2045
At a subsequent follow-up visit shortly after initial examination, the patient presented with new onset of decreased vision in the left eye and was found to have subretinal fluid and leakage at the choroidal level (Figure 2).
Hematoxylin and eosin stain of conjunctival biopsy demonstrating giant cells predominantly of the Touton type with leukemic cell infiltration of tissues.
opth-6-2045f3.jpg
PMC3526909_01_opth-6-2045f3.jpg
f3-opth-6-2045
Bilateral conjunctival biopsies were performed and revealed necrobiotic xanthogranuloma (Figure 3) with an adjacent CLL component.