PMC3876769_01
Clinical photograph showing the exophytic lesion on the left buccal mucosa.
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fig1
A-60-year old male patient presented with the chief complaint of a painless growth on the left buccal mucosa (Figure 1).
Showing epithelial hyperplasia with parakeratosis and elongated rete pegs. There is an abundance of foam cells in the connective tissue papilla (H&E stain 10x).
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fig2
Owing to the uniformly elongated rete pegs, deep connective tissue papillae were seen, some of which extended into overlying surface epithelium (Figures 2 and 3).
Presence of large numbers of lipid-laden foamy histiocytes confined to the connective tissue papillae (H&E stain 40x).
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fig3
Owing to the uniformly elongated rete pegs, deep connective tissue papillae were seen, some of which extended into overlying surface epithelium (Figures 2 and 3).
Showing foam cells with strong cytoplasmic CD68 immunostaining. The epithelial cells were negative (IHC stain 10x).
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fig4
All the foam cells were strongly stained with anti-macrophage antibodies (Figures 4 and 5).
The infiltrated foam cells in the papillary dermis were CD68 positive (IHC stain 40x).
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fig5
All the foam cells were strongly stained with anti-macrophage antibodies (Figures 4 and 5).
Showing the lesion after excision.
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fig6
The whole lesion was excised in one piece during excisional biopsy (Figure 6).