PMC3361768_01
Clinical picture showing the ulcerated growth with bleeding
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F1
The surface of the growth was covered with necrotic tissue with pus discharge and bleeding [Figure 1].
CT scan showing the expansile mass involving the maxillary sinus
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F2
The CT scan revealed a huge enhancing lesion involving the entire left maxillary sinus causing erosion of its superior, medial, and postero-lateral walls, extending up to the nasal cavity, left ethmoid sinus and retro maxillary space [Figure 2].
Pleomorphic undifferentiated epithelial cells in the form of nests and trabeculae separated by thin fibrous connective tissue septa (H&E, x10)
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F3
Microscopic examination of the biopsy specimen revealed pleomorphic undifferentiated epithelial cells in the form of nests and trabeculae separated by thin fibrous connective tissue septa [Figure 3].
Photomicrograph showing large cells with pleomorphic nuclei (H & E, x40)
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F4
The cells were of variable size and shape, large cells with amphophilic cytoplasm with round to oval diffusely hyperchromatic nuclei with or without small nucleoli are seen interspersed with cells which have vesicular nuclei and prominent nucleoli [Figure 4].
Photomicrograph showing positive reactivity to cytokeratin (x40)
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F5
Immunohistochemical assay revealed immunoreactivity of the neoplastic cells to cytokeratin (CK7, 8, 19) [Figure 5] and epithelial membrane antigen.