PMC5824520_01
Intraoral photograph showing an erythematous swelling
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F1
On palpation, the lesion was tender and firm in consistency [Figure 1].
Fine needle aspiration cytology showing epithelial cells with hyperchromatic nuclei and abundant eosinophilic cytoplasm suggestive of malignant neoplastic cells (x10)
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F2
Section showing intact surface epithelium of stratified squamous variety (H&E, x10)
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F3
Tumour cells were seen whorling around the nerve bundle showing neurotropism and thus demonstrating perineural invasion [Figures 3-7].
Section showing individual tumor cells in single file pattern (H&E, x10)
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F4
Tumour cells were seen whorling around the nerve bundle showing neurotropism and thus demonstrating perineural invasion [Figures 3-7].
Section showing minor salivary glands (H&E, x10)
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F5
Tumour cells were seen whorling around the nerve bundle showing neurotropism and thus demonstrating perineural invasion [Figures 3-7].
Section showing perineural invasion (H&E, x40)
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F6
Tumour cells were seen whorling around the nerve bundle showing neurotropism and thus demonstrating perineural invasion [Figures 3-7].
Picture on the lesional tissue (isomorphic small tumor islands) that helped us to identify it as polymorphous low-grade adenocarcinoma other than the single file pattern (x40)
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F7
Tumour cells were seen whorling around the nerve bundle showing neurotropism and thus demonstrating perineural invasion [Figures 3-7].
Section of the lesion stained with carcinoembryonic antigen showing strong positivity for tumor cells (x10)
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F8
Since E-cadherin is positive, gastric carcinoma was ruled out [Figures 8-11].
Immunohistochemical stain showed E-cadherin positivity (x10)
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F9
Since E-cadherin is positive, gastric carcinoma was ruled out [Figures 8-11].
Section of the lesion stained with vimentin showing strong positivity for tumor cells (x10)
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F10
Since E-cadherin is positive, gastric carcinoma was ruled out [Figures 8-11].
Section of the lesion stained with cytokeratin 7 showing strong positivity for tumor cells (x10)
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F11
Since E-cadherin is positive, gastric carcinoma was ruled out [Figures 8-11].
Histopathological picture of the recurrent lesion in the same site after surgery (x10)
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F12
On follow-up, it was noted that the patient underwent excision but turned up with recurrence of the lesion on the same site after 3 months for which she was further evaluated and monitored [Figures 12 and 13].
Clinical picture of recurrent lesion
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F13
On follow-up, it was noted that the patient underwent excision but turned up with recurrence of the lesion on the same site after 3 months for which she was further evaluated and monitored [Figures 12 and 13].