PMC4628255_01
Brain MRI scan of a patient with an intragenic tandem duplication in the PAFAH1B1 gene. Axial T2-weighted brain image indicating the occurrence of predominant agyria in the posterior regions, and pachygyria in the anterior regions. The patient was diagnosed with grade 3 lissencephaly
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Fig1
Magnetic resonance imaging (MRI) of the brain demonstrated a thickened cortex and gyral malformations that were more severe in the posterior brain regions than in the anterior brain regions (Fig. 1).