PMC2892698_01
CT scan demonstrating a large cystic anterior mediastinal mass (arrow).
CRM2010-795037.001.jpg
PMC2892698_01_CRM2010-795037.001.jpg
fig1
CXR remained unchanged after the course of antibiotics. CT scan demonstrated mediastinal lymphadenopathy and a 13 cm anterior mediastinal mass (Figure 1).
Hodgkin lymphoma in thymic cyst. (a) Wall of thymic cyst with nodules of cellular/inflammatory infiltrates (H&E. 25x). (b) Thymic cyst wall devoid of epithelium demonstrating the mixed inflammatory infiltrate in wall (H&E. 100x). (c) Hassel corpuscles surrounded by classic Reed-Sternberg cells in a mixed inflammatory background (H&E. 200x). (d) Classic Reed Sternberg cells present in a mixed inflammatory background of lymphocytes, histiocytes, and eosinophils (H&E. 400x).
CRM2010-795037.002.jpg
PMC2892698_01_CRM2010-795037.002.jpg
fig2
The neoplastic cells were present in nodules separated by dense fibrous septae (Figure 2).
Osteosarcoma: (a) gross photograph of resected specimen demonstrating a large lesion in scapula extending into soft tissue. (b) Representative microscopic section showing pleomorphic and spindle cells with hyperchromatic nuclei and osteoid production. (H&E. 200x).
CRM2010-795037.003.jpg
PMC2892698_01_CRM2010-795037.003.jpg
fig3
Biopsy of the periscapular mass demonstrated a chondroblastic osteosarcoma (Figure 3).
Bone marrow aspirate smear showing medium-to-large sized myeloblasts with moderate cytoplasm, round to lobulated or bean-shaped nuclei, and variably conspicuous nucleoli. (H&E. 400x).
CRM2010-795037.004.jpg
PMC2892698_01_CRM2010-795037.004.jpg
fig4
These blasts were medium-to-large sized with scanty-to-moderate cytoplasm, mostly fine red cytoplasmic granules, round to lobulated or bean-shaped nuclei, and variably conspicuous nucleoli (Figure 4).