PMC8504208_01
CT axial (a) and coronal (b) views show a poorly marginated mass occupying segments V, VI, VII, and VIII of the liver, which appears heterogeneous with central calcification.
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An abdominal CT (Figure 1) showed a heterogeneous mass in segments V, VI, VII, and VIII of the liver with chunky central calcifications, infiltration into the gallbladder, and no portal vein thrombosis were seen.
(a) and (b) Different liver core biopsies with mainly spindle cell lesions invading the fibrous stroma in clusters and strands with foci of epithelioid cells (white circle).
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A biopsy of the lesion (Figure 2) showed spindle cells, and the diagnosis was SHC.
Immunohistochemistry shows cytokeratin negative (a), background uptake of myoblast determination protein 1 without nuclear expression (b) and vimentin negative (c).
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Immunohistochemistry of the biopsy showed cytokeratin negative and vimentin negative stains; however, there was background uptake of myoblast determination protein 1 though no nuclear expression (Figure 3).