PMC7490444_01
Computed tomography (CT) manifestation of the lung lesion (arrowheads). Chest CT showing a pure ground glass opacity, with a maximum diameter of 8 mm, located in the subpleural area of the right upper lung.
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Center for the evaluation of a GGO, which was found incidentally within the right upper lung on computed tomography (CT). Chest CT showed a pure GGO lesion measuring 8 mm in diameter in the anterior segment of the right upper lobe (Fig. 1).
(A) Histopathologic features of a solitary pulmonary capillary hemangioma (SPCH). Hematoxylin and eosin staining (original magnification, x200) show alveolar structures with proliferated capillaries and enlarged endothelial cells without cytological atypia. (B-D) Immunohistochemical staining of the SPCH (original magnification, x200) revealed positivity for thyroid transcription factor-1 (B) in the nuclei of alveolar epithelial cells and for CD31 (C) and CD34 (D) in the cytoplasm of endothelial cells.
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Pathologic examination showed thickening of the alveolar septum caused by the proliferation of capillary vessels without cytological atypia (Fig. 2A). Immunohistochemistry revealed that this lesion was negative for thyroid transcription factor-1 (TTF-1, Fig. 2B) and cytokeratin and positive for CD31 and CD34 (Fig. 2C and D).