PMC7468538_01
Mammography presentations (2019.02.14).
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Mammography found a diffusely increased density of the left mammary gland with local distortion and fine sand-like calcification (BI-RADS.6) (Figure 1).
Breast MRI (2019.02.13).
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Breast MRI was carried out and showed a widely abnormal signal (with the largest measuring up to 8.7cm) and skin thickening in the left breast (BI-RADS.6), left nipple depression, fat pad edema in the subcutaneous and anterior areas of the pectoralis major muscle, and enlargement of the left axillary lymph node (Figure 2, Figure 3A).
Breast MRI imaging.
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Breast MRI was carried out and showed a widely abnormal signal (with the largest measuring up to 8.7cm) and skin thickening in the left breast (BI-RADS.6), left nipple depression, fat pad edema in the subcutaneous and anterior areas of the pectoralis major muscle, and enlargement of the left axillary lymph node (Figure 2, Figure 3A). After 2 cycles, breast MRI showed a significant reduction in the lesion size in the left breast (with the largest measuring up to 0.7cm) (Figure 3B) and a visibly reduced size of the lymph node in the left armpit, which was evaluated as clinical partial response (cPR) by efficacy assessment according to Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST1.1). After 4 cycles, the breast MRI results showed close to a clinical complete response (cCR) (Figure 3C).