PMC6620857_01
Bone marrow morphology at diagnosis showing infiltration by lymphoblasts.
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fig1
Bone marrow (BM) biopsy and aspirate demonstrated a 95% infiltration of lymphoblasts (Figure 1).
Sanger sequencing demonstrating presence of the e13a3 BCR-ABL1 fusion gene.
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Standardised RT-PCR and Sanger sequencing demonstrated e13a3 BCR-ABL1 transcripts (Figure 2).
Molecular monitoring of e13a3 BCR-ABL1 transcripts throughout clinical course. AlloSCT: allogeneic stem cell transplantation.
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fig3
BCR-ABL1 transcripts were not detected in the peripheral blood at one, two, and three and a half months post-ASCT (Figure 3).