PMC9109171_01
Chest X-ray PA upright showing bilateral hilar lymphadenopathy.
10.1177_23247096221097526-fig1.jpg
PMC9109171_01_10.1177_23247096221097526-fig1.jpg
fig1-23247096221097526
Imagings were significant for bilateral diffuse axillary and inguinal lymphadenopathy and hepatosplenomegaly (Figures 1-4).
CT chest coronal plane showing bilateral axillary, mediastinal and hilar adenopathy.
10.1177_23247096221097526-fig2.jpg
PMC9109171_01_10.1177_23247096221097526-fig2.jpg
fig2-23247096221097526
Imagings were significant for bilateral diffuse axillary and inguinal lymphadenopathy and hepatosplenomegaly (Figures 1-4).
CT abdomen/pelvis coronal plane showing diffuse adenopathy in the region of the hilum of spleen, retroperitoneum, and iliac chain. Also showing splenomegaly (17 x 17 cm) and hepatomegaly (20 cm in the cephalocaudal span).
10.1177_23247096221097526-fig3.jpg
PMC9109171_01_10.1177_23247096221097526-fig3.jpg
fig3-23247096221097526
Imagings were significant for bilateral diffuse axillary and inguinal lymphadenopathy and hepatosplenomegaly (Figures 1-4).
CT abdomen/pelvis axial plane showing adenopathy in the bilateral inguinal region.
10.1177_23247096221097526-fig4.jpg
PMC9109171_01_10.1177_23247096221097526-fig4.jpg
fig4-23247096221097526
Imagings were significant for bilateral diffuse axillary and inguinal lymphadenopathy and hepatosplenomegaly (Figures 1-4).
H&E stain of right inguinal lymph node at 4x magnification showing reactive plasma cell populations in the lymph node consistent with plasma cell variant of Castleman disease.
10.1177_23247096221097526-fig5.jpg
PMC9109171_01_10.1177_23247096221097526-fig5.jpg
fig5-23247096221097526
HHV-8 immunostaining showed presence of HHV-8 (Figures 5-7).
H&E stain of right inguinal lymph node at 20x magnification showing reactive plasma cell populations in the lymph node consistent with plasma cell variant of Castleman disease.
10.1177_23247096221097526-fig6.jpg
PMC9109171_01_10.1177_23247096221097526-fig6.jpg
fig6-23247096221097526
HHV-8 immunostaining showed presence of HHV-8 (Figures 5-7).
HHV-8 immunostaining of right inguinal lymph node at 20x magnification showing focally positive HHV-8 staining consistent with Castleman disease.
10.1177_23247096221097526-fig7.jpg
PMC9109171_01_10.1177_23247096221097526-fig7.jpg
fig7-23247096221097526
HHV-8 immunostaining showed presence of HHV-8 (Figures 5-7).