PMC3101317_01
Clinical photograph of a 39-year-old man with a 4x5 cm swelling on the mental region.
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F1
On examination, an approximately 4x5 cm mass was found to overlay the mental region (Figure 1).
This axial contrast-enhanced (soft tissue window) CT image shows a well-defined, radiolucent, with peripheral contrast enhancement mass, encircling the cortex of the bone partially (arrow). There is no signs of cortical destruction or medullary involvement.
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F2
There was no evidence of cortical destruction or medullary involvement (Figure 2).
A. Photomicrograph showing lobules of atypical chondroid admixed with small foci of malignant osteoid formation (arrow A). The tumor consists of highly atypical malignant chondroblastic cells (arrow B). (H&E, original magnificationx100).. B. Some mitotic figures are present among the chondrocytes (arrows). (H&E, original magnificationx100).. C. Some tumor cells show positive staining for antibodies against the S-100 protein. (original magnificationx 100).
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F3
The chondroid matrix component was composed of poorly differentiated, anaplastic chondroblastic cells (Figure 3A). In addition, mitotic figures were readily seen among the chondrocytes and osteocytes (Figure 3B). Immunohistochemically, the tumor showed diffuse reactivity with antibodies against vimentin and focal reactivity with antibodies against the S-100 protein in the chondroid containing fields and the spindle cells (Figure 3C).
A. Axial contrast-enhanced (soft tissue window) CT scan demonstrating a recurrent lesion (arrow) on the outer surface of the lingual cortex of the right posterior mandible.. B. Photograph of the resected recurrent tumor together with the residue of the right mandible.
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F4
After ten months the lesion recurred locally, which was located at the lingual bone cortex surface of the residual mandible on the right side (Figure 4A). We removed the tumor together with the residue of the right mandible (Figure 4B).