PMC10187644_01
(A and B) Chest CT showed consolidation of the outer basal segment of the left lower lobe, measuring 2.8x3.0x 3.5 cm, (C and D) Chest CT showed a reduced consolidation lesion measuring 2.0 cm x 2.6 cm x 3.0 cm, with ground glass density foci and cords surrounding the lesion, (E and F) Chest CT showed an increase in the size of consolidation to 2.0 cm x 2.7 cm x 3.1 cm and bilateral ground-glass opacities.
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Chest CT showed consolidation of the outer basal segment of the left lower lobe, measuring 2.8 x3.0x 3.5 cm (Figure 1A and B). Persistent hemoptysis led to repeat chest CT, which revealed a reduced consolidation lesion measuring 2.0 cm x 2.6 cm x 3.0 cm, with ground glass density foci and cords surrounding the lesion (Figure 1C and D). CT showed an increase in the size of consolidation to 2.0 cm x 2.7 cm x 3.1 cm and bilateral ground-glass opacities (Figure 1E and F).
(A-E) Lobectomy histopathology images showing (A) the original magnification, 0.4x, (B) the original magnification, 10x, (C) the original magnification, 40x, and (D and E) Gomori methenamine silver and periodic acid-Schiff stain positivity of the bacterial colonies.
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Under a microscope, chrysanthemum shapes in the lumen and dense centres of intertwined, branched hyphae surrounded by radially-arranged eosinophilic long hyphae were observed; Glan staining was positive, and epithelioid cells surrounded the granules, macrophages, lymphocytes, and other inflammatory cells, which were positive for hexamine silver and Periodic Acid-Schiff stain (Figure 2).