PMC5220420_01
Timeline of ALT changes.
CRIGM2016-7092434.001.jpg
PMC5220420_01_CRIGM2016-7092434.001.jpg
fig1
A liver biopsy on day 6 showed severe interface hepatitis with a mixed inflammatory infiltrates consistent with severe AIH (Figure 1).
Liver biopsy showing severe interface hepatitis with moderate to severe mixed inflammatory infiltrates.
CRIGM2016-7092434.002.jpg
PMC5220420_01_CRIGM2016-7092434.002.jpg
fig2
ALT dropping to 85 IU/L within 10 days. After this initial response, her ALT rose again to 421 U/L despite remaining budesonide (Figure 2).