PMC10129404_01
(a and b): Histopathological examination showing densely cellular nests and trabeculae with rounded margins with delicate fibrovascular stroma separating them. Neoplastic cells were larger and polygonal, with eosinophilic, granular cytoplasm and coarse and fine nuclear chromatin. (Figure 1a : 4x magnification; 1b : 20x magnification).
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Neoplastic cells were larger and polygonal, with eosinophilic, granular cytoplasm and coarse and fine nuclear chromatin (Figure 1a and b).
(a and b): IHC panel for NE markers (Figure 3a : NSE-positive status; 3b : SYN-positive status).
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More than 90% of the cells were strongly positive for neuron-specific enolase (NSE) and SYN (Figure 2a and b).
IHC for ki-67 proliferation index showing 10%.
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Ki-67 proliferation index was 10% (Figure 3).