PMC7173800_01
Bone marrow aspirate (1000x) using wright stain and chromosome study on first admission. (A) A BM study revealed acute myeloid leukemia. (B) A chromosome study revealed a karyotype of 46, XY, t(9; 22)(q34; q11) in all 20 cells analyzed.
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A BM study (Figure 1) revealed hypercellular marrow with 25% blasts (Table 1). A chromosome study revealed a karyotype of 46, XY, t(9; 22)(q34; q11) in all 20 cells analyzed (Figure 1).
Immunophenotyping by flow cytometry of the blasts at acute myeloid leukemia phase.
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Immunophenotyping by flow cytometry suggested that the blasts were positive for cytoplasmic myeloperoxidase (MPO), CD4, CD11b, CD15, CD16, CD33, CD34, CD38, CD56, and CD71 (Figure 2).
Bone marrow aspirate (1000x) using Wright stain and chromosome study on second admission. (A) A BM study revealed acute B-lymphoid leukemia. (B) A chromosome study revealed a karyotype of 46, XY, t(9; 22)(q34; q11) in all 20 cells analyzed.
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Similar to the first admission, a chromosome study revealed a karyotype of 46, XY, t(9; 22)(q34; q11) in all 20 cells analyzed (Figure 3).
Immunophenotyping by flow cytometry of the blasts at acute B-lymphoid leukemia phase.
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Immunophenotyping by flow cytometry suggested that the blasts were positive for cytoplasmic CD22, cytoplasmic CD79a, and CD10, CD19, CD20, CD33, CD38, CD117, HLA-DR with membrane-expressed (Figure 4).