PMC4246144_01
Racemase stain (arrow) highlighting Gleason (3+4) adenocarcinoma.
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Prostate biopsy revealed concurrent small cell carcinoma (SCC) of the prostate and a minor component of high-grade adenocarcinoma, Gleason (3 +4) (Figs.  1-3 ).
CD-56 stain highlighting areas of small cell carcinoma (area stained brown is positive for CD-56).
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Prostate biopsy revealed concurrent small cell carcinoma (SCC) of the prostate and a minor component of high-grade adenocarcinoma, Gleason (3 +4) (Figs.  1-3 ).
Synaptophysin statin highlighting areas of small cell carcinoma (area staining brown is positive for SCC).
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Prostate biopsy revealed concurrent small cell carcinoma (SCC) of the prostate and a minor component of high-grade adenocarcinoma, Gleason (3 +4) (Figs.  1-3 ).
(a) PET CT showing hypermetabolic lesions in L scapula and L Iliac wing suggestive metastatic disease (solid arrows). (b) PET CT in in coronal section showing hyper lucent lesion in L scapula; note the absence of PET CT findings in lung tissue which is pathognomonic of neuroendocrine tumors.
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Positron emission tomography (PET) scan showed evidence of metastasis to bone (Fig. 4), with the largest most hypermetabolic foci in the left scapula, left iliac wing and lymph nodes of the thorax and lung.
(a) Represents a non-contrast CT scan (mediastinal window) with arrow showing paratracheal lymphadenopathy and (dashed arrow) showing R sided pleural effusion. (b) CT scan showing R sided opacification with concern for pneumonia vs. post bronchial obstruction and concern for malignancy (this was the lesion that was biopsied).
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CT scan showed mediastinal lymphadenopathy with a right middle lobe opacification concerning for post bronchial obstruction (Fig. 5).