PMC6000767_01
Initial clinical presentation of lesions.
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In October 2016, the patient presented with a stage III left upper limb lymphedema with the appearance of isochromic nodular lesions of the skin (Fig. 1, Fig. 2).
Clinical presentation of multiple nodular reddened lesions.
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The patient underwent therapy with physiotherapy, bandages and plastic devices; in December 2016, however, the patient reported further diffusion and reddening of the skin lesions affecting the left upper limb (Fig. 3, Fig. 4). The physical examination revealed the presence of painless non-confluent oval nodular lesions, distributed on the volar surface of left arm and forearm.