PMC4008894_01
A 66-year-old Caucasian male with juxtapapillary choroidal metastasis (a-c) before treatment and regressed tumor (d-f) after plaque radiotherapy
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F1
OS. Ophthalmoscopy disclosed a solitary, juxtapapillary yellow-white choroidal tumor measuring 5 x 3 mm in diameter [Figure 1].
PMC4008894_02
A 62-year-old Caucasian male with superonasal equatorial choroidal metastasis (a), with high to medium internal reflectivity on A scan (b) and mushroom shaped configuration on B-scan ultrasonography (c). Fine needle aspiration biopsy yielded a cohesive cluster of atypical spindle cells with hyperchromatic, elongated nuclei (d) and a mitotic figure (black arrow) (e) (Papanicolaou stain). Following plaque radiotherapy, tumor regression was documented but persistent vitreous hemorrhage and retinal detachment lead to poor visual acuity
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F2
Ophthalmoscopy revealed a solitary, superonasal, ciliochoroidal mass, 13.7 mm in basal diameter [Figure 2a]. Ultrasonography disclosed a mushroom-shaped choroidal mass measuring 9.7 mm in thickness and with subretinal fluid [Figure 2b and c]. FNAB of the mass showed clusters of atypical spindle cells with elongated, hyperchromatic nuclei and irregular nuclear membrane [Figure 2d]. Occasional small nucleoli and mitotic figures were observed [Figure 2e].