PMC6350541_01
(a) Hematoxylin and eosin stain show typical histopathological appearance of acute interstitial lesions in light microscopy. (b) Hematoxylin and eosin stain shows diffusive interstitial infiltration of polymorphic inflammatory cells, predominantly T-cells, monocytes, and eosinophils.
CRIN2019-3614980.001.jpg
PMC6350541_01_CRIN2019-3614980.001.jpg
fig1
Light microscopy showed severe interstitial nephritis with infiltration of polymorphic inflammatory cells (Figure 1(a)). Inflammatory infiltrates were also present in the tubular basement, and tubular epithelial cells exhibited diffusive degenerative lesions; interstitial granulomas were not present (Figure 1(b)).