PMC5952443_01
Cutaneous lesion in the lateral aspect of right thigh measuring 4 cm x 3 cm.
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fig1
A 68-year-old female with no significant past medical history presented with a rapidly progressing painless extrinsic irregular mass on her lateral aspect of right thigh for three-month duration (Figure 1).
A large, friable, and infiltrative tumor which occupied 50 to 74% of the circumference of the ascending colon.
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fig2
It was not causing significant narrowing (Figure 2).
Ascending colon biopsy showing poorly differentiated invasive adenocarcinoma (H&E, x400).
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fig3
An immune-peroxidase stain panel done showed CAM5.2 positive, 34 BE12 positive, CDX-2 positive, CEA positive, CK-7 negative, and CK-20 negative, TTF-1 negative consistent with adenocarcinoma of colon (Figure 3).