PMC2926582_01
A dome-shaped faintly pinkish nodule. The surface of the tumor was covered with yellow papules.
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fig1
The surface of the tumor was covered with yellow papules (Figure 1).
Yellowish homogeneous ovoid areas and arborizing vessels at the periphery of the nodule.
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fig2
Dermoscopic examination demonstrated yellowish homogeneous ovoid areas covered with translucent whitish veil and arborizing vessels at the peripheral peach-colored area of the nodule (Figure 2).
A well-circumscribed, smooth-bordered, and deeply basophilic tumor in the dermis.
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fig3
Histopathological examination of the excised nodule revealed a well-circumscribed and smooth-bordered neoplasm in the entire dermis with partial connection to the epidermis (Figure 3).
The tumor is composed of basaloid cells with deeply basophilic oval nuclei showing a typical rippled pattern.
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fig4
In addition, the tumor focally showed a typical "rippled pattern" (Figure 4).
The cells simulating Verocay bodies are positive for AE1/AE3.
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fig5
The cells were arranged in linear rows parallel to one another, simulating Verocay bodies, which were positive for AE1/AE3 (Figure 5) but negative for S-100 protein.
A few sebocytes are seen at the periphery of the tumor nests.
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fig6
There were only a few vacuolated cells with foamy and bubbly cytoplasm, suggesting sebaceous differentiation especially at the superficial area of the region (Figure 6).
Sebocytes seen at the periphery of the tumor nests are positive with adipophilin.
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fig7
These cells possess lipid vacuoles which were highlighted with adipophilin antibody (Figure 7).