PMC5474483_01
Flowchart for the patient. IVF, In vitro fertilization; FET, Frozen embryo transfer; AVM, Abnormal vaginal microbiota.
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F1
In the present case-report, we discuss the clinical management of a couple attending their first frozen embryo transfer (FET) cycle following two failed fresh IVF cycles, see flowchart in Figure 1. After the two failed fresh IVF cycles and considering the history of recurrent pregnancy loss (Figure 1), a hysteroscopy was performed where endometrial adhesions were excised.
Treatment of abnormal vaginal microbiota for 7 days with clindamycin in an IVF patient. Y-axis represents copy numbers (copies/mL) from qPCR analysis. X-axis represents the sampling time, i.e., 1 means day 1 after first clindamycin intake. ET, Embryo transfer at 8 days follow-up.
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F2
As shown in Figure 2, the short- and long-term treatment efficacy from oral clindamycin on AVM was excellent resulting in rapid eradication of G. vaginalis.