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Cranial MRI in Case 1. Axial T2 weighted (A) and FLAIR (B) sequences showed hyper-intensity in the right hippocampus. 20 months after immunotherapy, a control cranial MRI showed a significant reduction of right hippocampus hyper-intensity in T2 (C) weighted and FLAIR (D) sequences. 28 months after immunotherapy, no significant changes contrasted (E, F) with (C, D).
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A cranial MRI showed hyper-intensity in the right hippocampus on T2 and fluid attenuated inversion recovery (FLAIR) sequences ( Figure 1 ). However, a follow-up cranial MRI showed a significant reduction of right hippocampus hyper-intensity on T2 weighted and FLAIR sequences ( Figure 1 ).
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Cranial MRI in Case 3. Axial T2 weighted (A) and FLAIR (B) sequences showed hyper-intensity in the left hippocampus. 2 months after immunotherapy, a control cranial MRI showed a significant reduction of right hippocampus hyper-intensity in T2 weighted (C) and FLAIR (D) sequences.
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Cognitive Assessment (MoCA) and 16/30 on the Mini-Mental State Examination (MMSE). Cranial MRI showed hyper-intensity on T2 and FLAIR sequence in the left hippocampus ( Figure 2 ).
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