PMC8616702_01
Coronal CT of sinonasal mass with complete opacification of left paranasal sinuses (a) and sagittal CT of mass extending from the nasal cavity down to oropharynx in contact with the soft palate (b).
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Computed tomography (CT) of the sinuses was concerning for a mass extending from the left maxillary sinus antrum to the nasopharynx and oropharynx with complete opacification of the adjacent paranasal sinuses (Figure 1).
Photomicrographs of tumor sections. Sections shown above include (a) inverted papilloma (H&E, 10x); (b) poorly differentiated squamous cell carcinoma (H&E, 10x); (c) surface ulceration with underlying rhabdoid tumor phenotype (H&E, 10x); (d) rhabdoid tumor cells with prominent perinuclear acidophilic zone (H&E, 40x); (e) sarcomatoid focus within tumor and cytoplasmic globoid bodies in rhabdoid tumor cells (CAM 5.2 positive immunostain, 20x); (f) proliferative index of 20% (MIB1 immunostain, 20x).
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Pathologic examination revealed a poorly differentiated composite sinonasal carcinoma with rhabdoid phenotype, foci of sarcomatoid cells, and SCC arising within an inverted papilloma (Figure 2).