PMC6614379_01
Skin lesions in a patient with Chikungunya Fever before (a-c) and after (d-l) intravenous treatment with intravenous immunoglobulin IVIG-Flebogamma .
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F1
International Normalized Ratio (INR) of 1.45 and Prothrombin Time of 56%, edema in his hands and feet and hemorrhagic bullous lesions on the skin of the upper and lower limbs (Figures 1a-c), being admitted to the Intensive Care Unit. Immediately, therapy was started with meropenem and vancomycin, then maintained for 6 days, during which the patient presented some febrile peaks. Ten days after globulin administration, a substantial improvement of the bullous lesions was observed (Figures 1g-l).