PMC10358273_01
The image of the tumor. Skull base CT showed a mass with adjacent bone destruction in the sellar region (A, B: brown arrow). MRI showed a tumor with a clear boundary with mild enhancement after injection of a contrast agent (C, D: yellow arrow). The abdominal CT showed multiple tumors in the liver. Tumors are filling in the portal vein lumen (E: blue arrow). Bilateral iliac bones were destroyed due to metastasis (F, G: red arrow).
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CT showed a pituitary mass with adjacent bone destruction ( Figures 1A, B ). MRI revealed a tumor with enhancement in the pituitary fossa ( Figures 1C, D ). After removing the tumor, the abdominal CT showed multiple inhomogeneous tumors with the portal vein invasion and multiple bilateral ilium metastasis ( Figures 1E-G ), and single photon emission computed tomography (SPECT) showed high metabolism in the bilateral iliac bone ( Figure 2A ). The final diagnosis was pituitary metastasis of HCC and HCC. The postoperative images showed that the tumor was completely resected ( Supplementary Figure 1 ).
The image and pathology of lesions. The single photon emission computed tomography showed 99 mTC-MDP aggregated in the bilateral iliac bones (A: blue arrow). Hematoxylin and eosin staining of the pituitary tumor demonstrates a tumor with nuclei of different shapes (B). Multinuclear giant cells (black arrow) and carcinoma cells (red arrow). Immunohistochemical expression of metastatic hepatic carcinoma glypican-3 (C). The abdominal MRI showed multiple tumors with portal vein tumor embolus (D, E: yellow arrow).
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After removing the tumor, the abdominal CT showed multiple inhomogeneous tumors with the portal vein invasion and multiple bilateral ilium metastasis ( Figures 1E-G ), and single photon emission computed tomography (SPECT) showed high metabolism in the bilateral iliac bone ( Figure 2A ). TSH, ACTH, FSH, LH, PRL, S100, and P63 ( Figures 2B, C ). The abdominal MRI showed multiple tumors with obstruction of the bile duct ( Figures 2D, E ).