PMC10319459_01
Gross images of the jejunal mass with hemorrhages and necrosis at low (a) and high (b) magnification.
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fig1
On cut surface, the mass lesion showed a transmural heterogenous solid tumor with areas of hemorrhage and necrosis (Figure 1).
Microscopic features of jejunal pleomorphic liposarcoma: (a) heterogenous population of tumor cells; (b) scattered lipoblasts (arrow); (c) pleomorphic malignant cells with few multinucleated giant cells; (d) PASD positive intracytoplasmic globules. Original magnifications: (a) 20x; (b-d) 400x.
CRIPA2023-8040232.002.jpg
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fig2
Microscopic examination of the mass showed a high-grade malignant tumor consisting of solid sheets of epithelioid cells (Figure 2(a)), some with intracytoplasmic fatty droplets, scalloped nuclei consistent with lipoblasts (Figure 2(b)), and scattered multinucleated giant cells (Figure 2(c)). Numerous intracytoplasmic PASD-positive hyaline eosinophilic globules were present in some tumor cells (Figure 2(d)).
Jejunal pleomorphic liposarcoma with diffusely positive for p53 by immunohistochemistry. Original magnification: 100x.
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fig3
P53 was diffusely positive in nuclei suggestive of mutant phenotype (Figure 3).