PMC4327571_01
CT scan showing multiple right frontal lesions.
crg-0009-0001-g01.jpg
PMC4327571_01_crg-0009-0001-g01.jpg
F1
Magnetic resonance imaging of the brain showed multiple right frontal and right parietal lesions with perilesional edema (fig. 1).
a Explanted cirrhotic liver. H&E, x40. b Explanted liver with multiple copper deposits. Copper, x40. c, d Brain abscess, PAS-D, x40 (c) and Gomori, x40 (d), presenting formations morphologically consistent with Aspergillus spp.
crg-0009-0001-g02.jpg
PMC4327571_01_crg-0009-0001-g02.jpg
F2
The explanted cirrhotic liver revealed abundant copper deposits (fig. 2a, b). Fragments of brain parenchyma showed edema, extensive necrosis, neutrophil infiltration in abundant quantity, apoptotic cells and presence of abundant septate hyphae angled at 45 , morphologically compatible with Aspergillus spp. (fig. 2c, d), corroborated by the PAS-D and Gomori stains.