PMC6145540_01
(A) Solid pseudopapillary neoplasm in pancreatic tail at the time of presentation, (B) recurrent mass in the splenic fossa. Histological features of the recurrent tumor: (C) characteristic pseudopapillary architecture observed on microscopy (H&E 100 x ), (D) lymphovascular invasion by tumor, (E) mitotic figures (6 in 10 high-power fields), (F) fibrovascular core with discohesive tumor cells.
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A 42-year-old man presented to our pancreas multidisciplinary clinic after a computed tomography (CT) scan (Fig. 1A), prompted by a 2-month history of generalized bloating and epigastric discomfort, that demonstrated a 11.2 x 9.6 cm heterogeneous solid appearing mass in the tail of the pancreas. Four years later, he was referred back to our clinic after discovery of a biopsy-proven recurrence in the splenic fossa (Fig. 1B).