PMC5623769_01
Computed tomography (CT) of the chest in the axial plane with (a) bone window and (b) soft tissue window.
CRIRA2017-8135957.001.jpg
PMC5623769_01_CRIRA2017-8135957.001.jpg
fig1
Magnetic resonance imaging (MRI) of the T-spine was obtained to further characterize the degree of cord compression and showed the same infiltrating mass filling the left T2-T3 neural foramen (Figures 1 and 2).
Magnetic resonance imaging (MRI) of the thoracic spine in the axial plane with (a) T1-weighted sequence without contrast, (b) T1-weighted sequence with contrast, and (c) T2-weighted sequence.
CRIRA2017-8135957.002.jpg
PMC5623769_01_CRIRA2017-8135957.002.jpg
fig2
Magnetic resonance imaging (MRI) of the T-spine was obtained to further characterize the degree of cord compression and showed the same infiltrating mass filling the left T2-T3 neural foramen (Figures 1 and 2).
Bone scan showing tracer uptake in the upper T-spine and left 4th rib, corresponding to areas of direct tumour involvement.
CRIRA2017-8135957.003.jpg
PMC5623769_01_CRIRA2017-8135957.003.jpg
fig3
A bone scan was notable for tracer uptake in the left 4th rib and T2-T3 spine, correlating with direct tumour involvement (Figure 3).
Intermediate power view of the tumour showing a cellular proliferation of pleomorphic cells with epithelioid morphology (H&E stain, 200x original magnification).
CRIRA2017-8135957.004.jpg
PMC5623769_01_CRIRA2017-8135957.004.jpg
fig4
Histologic examination showed a proliferation of markedly pleomorphic cells, with some demonstrating epithelioid morphology (Figure 4), interlaced with cellular regions showing a spindled, sarcomatoid appearance (Figure 5).
Intermediate power view of the tumour reflecting the spindled, sarcomatoid component (H&E stain, 200x original magnification).
CRIRA2017-8135957.005.jpg
PMC5623769_01_CRIRA2017-8135957.005.jpg
fig5
Histologic examination showed a proliferation of markedly pleomorphic cells, with some demonstrating epithelioid morphology (Figure 4), interlaced with cellular regions showing a spindled, sarcomatoid appearance (Figure 5).
Pan-cytokeratin immunohistochemistry, accentuating the epithelial component within the tumour (200x original magnification).
CRIRA2017-8135957.006.jpg
PMC5623769_01_CRIRA2017-8135957.006.jpg
fig6
Pan-cytokeratin and other epithelial markers accentuated the distinct epithelial component (Figure 6), while smooth muscle actin and CD31 immunohistochemistry highlighted the spindled, sarcomatoid regions (Figure 7).
Smooth muscle actin immunohistochemistry, demonstrating reactivity in the mesenchymal component (200x original magnification).
CRIRA2017-8135957.007.jpg
PMC5623769_01_CRIRA2017-8135957.007.jpg
fig7
Pan-cytokeratin and other epithelial markers accentuated the distinct epithelial component (Figure 6), while smooth muscle actin and CD31 immunohistochemistry highlighted the spindled, sarcomatoid regions (Figure 7).