PMC7305368_01
Chest roentgenogram shows bilateral diffuse micronodular opacities.
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The chest roentgenogram showed bilateral diffuse micronodular opacities (Fig. 1).
Histopathology shows malignant glands and papillary structures with psammoma bodies and cells with classic papillary thyroid carcinoma nuclear features (H&E, 400x magnification).
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Histopathology of the core biopsy showed focal involvement by metastatic carcinoma demonstrating papillary-cystic growth with scattered solid islands and psammoma bodies (Fig. 2).
TTF1 immunohistochemistry labels the neoplastic cells (400x magnification).
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Immunohistochemical interrogation revealed positivity with cytokeratin (CK) 7, thyroid transcription factor 1 (Fig. 3), and thyroglobulin.