PMC4763672_01
Clinical photographs (a, b) and results from histological studies (c-e). (a) At the first visit, erythematous papules and small brown nodules were seen on the left side of the chest, left axilla and left upper arm. (b) At 4 weeks after completion of treatment, all eruptions had faded and post-inflammatory hyperpigmentation was seen. (c) A dense nodular infiltration of hematoxylin-stained cells was present in the whole dermis (H and E, x40). (d) Large convoluted lymphocytes showing a clear perinuclear halo predominated in the infiltrate and small numbers of eosinophils were also present (H and E, x400). (e) In a specimen stained with CD4, a mite was detected within the stratum corneum of the epidermis (original magnification, x100)
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F1
At her first visit to our department, erythematous papules and small brown nodules were seen on the left side of her chest, left axilla and left upper arm [Figure 1a]. Histopathology specimens stained with hematoxylin and eosin (H and E) taken at the previous hospital showed features of CTCL without epidermal Pautrier microabscesses [Figure 1c and d]. Immunohistochemically, the infiltrating cells were positive for CD3 and CD4 [Figure 1e]. In a specimen stained with CD4, a mite was detected within the stratum corneum of the epidermis [Figure 1e]. After 4 weeks, all eruptions disappeared and only hyperpigmentation remained [Figure 1b].