PMC7481255_01
Images of positron emission tomography/computed tomography (PET-CT).. CT showed a massive loculated pleural effusion in the right thorax (A). PET-CT showed an enlarged left subclavicular lymph node with accumulation of fluorodeoxyglucose (FDG) (B, D). PET-CT also showed diffuse thick wall lesions and accumulation of FDG along the edge of the pleura and in multiple mediastinal lymph nodes (C, D).
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Chest radiography revealed a massive loculated pleural effusion in the right thorax (Fig. 1A). PET-CT revealed diffuse thick pleural lesions, massive pleural effusion, and enlarged mediastinal, left subclavicular and abdominal lymph nodes, and these lesions had accumulation of fluorodeoxyglucose (FDG) (Fig. 1B-D).
Images of pleural effusion cytology.. Cytology of pleural effusion showed large atypical cell with poor connectivity and coarse chromatin aggregation. (A, haemotoxylin & eosin staining, B, Giemsa staining).
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Cytology results of the pleural effusion showed malignancy which suggesting haematological tumor (Fig. 2A-B).
Images from thoracoscopy.. Thoracoscopy revealed diffuse rough and irregular mucosa of the pleura with redness and swelling (A, B).
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Thoracoscopy revealed diffuse rough and irregular mucosa of the pleura with redness and swelling (Fig. 3A-B).
Histopathology of pleural biopsy specimens.. Diffuse, large, atypical, naked nuclear cells infiltrated the centre of the tissues. (A, haemotoxylin & eosin staining, x 100). Lymphoma cells expressed CD20 on their cellular membrane, which suggested B-cell lymphoma (B, CD20 staining, x 100).
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A biopsy of the pleura with thoracoscopy revealed DLBCL (Fig. 4A-B).