PMC7142340_01
The specimen contained a cystic mass in the dermis, with overlying normal epidermis (a). The cystic areas were surrounded by neutrophils, histiocytes, and large binucleated and multinucleated malignant cells with Hodgkin and Reed-Sternberg morphology (b) that were positive for CD30 (c) and CD15 (d) on immunostains. CD15 also stains admixed neutrophils.
CRIHEM2020-1945058.001.jpg
PMC7142340_01_CRIHEM2020-1945058.001.jpg
fig1
Immunohistochemical (IHC) staining showed that the malignant cells were strongly positive for CD30, CD15, PAX5, and CD79a and negative for CD45, diagnostic of classical Hodgkin lymphoma (Figure 1).