PMC10282651_01
(A,B): Abdominal MR T1 and T2-weighted images. (C): LAMN and NEN (red circle), hematoxylin and eosin (H & E) staining 10x. (D): Immunohistochemistry positive for Cg A. (E): Immunohistochemistry for Ki-67: proliferation index of 0.4%.
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F1
Abdominal magnetic resonance imaging (MRI) also described a tumor close to the right ovarian gland (69 mm x 40 mm x 46 mm), with contrast enhancement in the arterial phase and clear margins afterward and a small nodulation inside (Figures 1A,B). On histological examination, the bigger mass was described as a LAMN with acellular mucus confined to the wall (TNM Classification 8th edition 2016: pTis), whereas the smaller nodule was described as a NEN G1, characterized by mesenteric fat and visceral serous membrane involvement measuring 0.9 and 0.5 mm, respectively (Figure 1C). Immunohistochemical analysis revealed positivity for cromogranin A (Cg A) (Figure 1D) and synaptophysin, with a Ki-67 proliferation index of 0.4% (Figure 1E) (TNM Classification 8th edition 2016: pT2G1).
PMC10282651_02
(A,B): abdominal MR T2- and T1-weighted images. (C): LAMN (red arrow) and NEN G1 (black arrow), (hematoxylin and eosin (H & E) staining).
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F2
Figure 2B)] in the right uterus space. Final radiological diagnosis was hydrosalpinx. Histologically (Figure 2C), the specimen appeared to be a LAMN with a fully thick mucus on the appendicular wall, but no peri-appendicular adipose tissue was involved (TNM Classification 8th edition 2016: pTis).