PMC9309382_01
Time course of clinical symptoms and signs as well as results from ancillary examinations and therapeutic interventions from symptom onset to death. Inserted graph shows serial serum neurofilament light chain levels (sNFL) from Feb to Nov 2020, coloured lines give age- and BMI-adjusted percentiles of reference population. UL, upper limbs; LL, lower limbs; ENMG, electroneuromyography.
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F1
The time course of both, clinical evolution and results of ancillary examinations are depicted in Figure 1. Serum NfL levels remained highly elevated and only slightly decreased at last follow-up [107.9 pg/ml; >99.9th percentile (see Figure 1)].