PMC3440933_01
Gray-scale ultrasound image shows a well-circumscribed nodule.
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F1
The ultrasound showed a circumscribed hypoechoic nodule which was avascular on color Doppler ultrasound [Figure 1].
Axial T1 -weighted MR image at the level of the nipple demonstrates a small, well circumscribed nodule lateral to left nipple of intermediate signal.
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F2
Dynamic, fat saturated magnetic resonance performed immediately after intravenous contrast administration at the same level as Figure 2 demonstrates avid enhancement of the lesion lateral to the left nipple.
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F3
There was avid early homogenous enhancement following contrast administration [Figure 3] with plateau formation seen on dynamic enhancement curve following initial early washout of contrast [Figure 4].
Hematoxylin and Eosin stained tissue at x40 low power view shows hemangioma (black arrows) and breast ducts and lobules (gray arrows).
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F4
There was avid early homogenous enhancement following contrast administration [Figure 3] with plateau formation seen on dynamic enhancement curve following initial early washout of contrast [Figure 4].
Hematoxylin and Eosin stained tissue at x400 high power view reveals abnormal vascular spaces in the hemangioma (arrows).
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F5
The nodule was of uncertain significance and was excised for histological assessment. This confirmed a diagnosis of capillary breast hemangioma [Figures 5, 6]. The nodule was completely excised.
This is a dynamic enhancement curve mapping lesion enhancement with time following contrast administration. It shows rapid initial enhancement, a peak, minor washout and then a plateau formation. This is an intermediate type of curve - malignant lesions have the rapid enhancement but also tend to washout rapidly as well - i.e. there is steeper curve drop as compared to what is seen in this image.
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F6
The nodule was of uncertain significance and was excised for histological assessment. This confirmed a diagnosis of capillary breast hemangioma [Figures 5, 6]. The nodule was completely excised.