PMC8630549_01
Histologic findings in liver biopsy.. Mild lobular hepatitis with few apoptotic bodies (arrow) surrounded by mononuclear inflammatory cells (arrowhead). Hematoxylin-eosin staining, original magnification X400.
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We consequently performed a percutaneous liver biopsy, which showed nonspecific acute lobular hepatitis with no evidence of endotheliitis and negative immunohistochemical staining for herpes viruses ( Figure 1).
Clinical course of the disease for the present case report.. Evolution of fever and liver function tests as well as results of SARS-CoV-2 PCR and serology. Serology testing for SARS-CoV-2 was performed by the Luminex S protein trimer IgG assay, as previously described


. Results are expressed in mean fluorescence intensity ratio with a positive cut-off of 6. ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; gamma-GT, gamma-glutamyltranspeptidase.
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Figure 2, the patient's condition progressively improved despite persistent low-grade fever at discharge, while transaminases steadily declined and eventually returned back to normal within 30 days. Fever had completely resolved after six weeks of follow-up.