PMC5586883_01
Surgical specimen showing the gastric wall diffusely thickened and ulcerated.
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F1
The gastrectomy measured 35.5 cm along the greater curvature and 11.5 cm along the lesser curvature and showed a diffusely thickened wall with ulcerated mucosa involving fundus to antrum (fig. 1).
High-power histopathological analysis of gastric tissue showing the concomitant presence of a signet ring cell carcinoma associated with MALT-lymphoma. HE. x400.
mpp-0023-0377-g02.jpg
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F2
The related histopathological findings showed intermingled areas of poorly differentiated signet ring cell carcinoma and diffuse monotonous sheets and nodules of small lymphoid cells with centrocyte morphology (fig. 2).
Histopathological analysis of gastric tissue, in which lymphoid cells show a strong positivity for CD20 at immunohistochemical assay. HE. x200.
mpp-0023-0377-g03.jpg
PMC5586883_01_mpp-0023-0377-g03.jpg
F3
At immunohistochemical assay, the lymphoid cells were diffusely positive for CD20 (fig. 3) and BCL2 and focally positive for CD43.