PMC9699881_01
Lumbosacral spine MRI T2 sequence showing soft tissue lesion at the level of L3-L4 (yellow bar).
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F1
It was isointense to hypointense on T1W, hypointense on T2W images [Figure 1] and enhanced with contrast.
Spinal granular cell tumor. (a) The tumor is composed of sheets of polygonal tumor cells with abundant eosinophilic granular cytoplasm (Hematoxylin and Eosin, original magnification x20). (b-d) The tumor cells are diffusely positive for S-100, SOX-10, and inhibin (original magnification x20).
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F2
It revealed polygonal tumor cells with abundant, eosinophilic, and granular cytoplasm arranged in sheets [Figure 2a]. Immunohistochemically, the tumor cells were diffusely positive for S-100, SOX-10, and inhibin [Figures 2b-d] and showed patchy positivity for CD68.