PMC8140758_01
first case with erythema and post bullous erosions in the face with crusty cheilitis
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F1
Nikolsky's sign was positive, the affected skin surface was estimated to be 30%, and the mucosal involvement was limited to a simple cheilitis (Figure 1, Figure 2).
first case with erythema and bubbles in arms and back of the hand
PAMJ-38-236-g002.jpg
PMC8140758_01_PAMJ-38-236-g002.jpg
F2
Nikolsky's sign was positive, the affected skin surface was estimated to be 30%, and the mucosal involvement was limited to a simple cheilitis (Figure 1, Figure 2).
PMC8140758_02
second case with erythematous and squamous plaques on the face and chest with crusty cheilitis
PAMJ-38-236-g003.jpg
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F3
The Mucocutaneous examination showed erythematous and squamous plaques on malar cheeks, arms and chest; vesicles and blisters on the cleavage and a crusty cheilitis without lesions on the oral cavity (Figure 3).
second case: histological section showing epidermal necrosis and interface dermatitis
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F4
A skin biopsy was taken from the chest; microscopic examination showed a superficial and deep perivascular infiltrate of lymphocytes and a sub epidermal bulla (Figure 4); the hair follicles were atrophic and eaten away by lymphoid elements and mucin deposits identified by the alcian blue coloring.