PMC3884174_01
Clinical and histopathological features illustrating the local recurrent lesion. a Clinical photograph of the subcutaneous induration on the periphery of the skin graft (arrow: Case 4). b Histopathology of the recurrent lesion demonstrated intradermal proliferation of EPC cells (Case 4; HE; x20).
cde-0005-0259-g03.jpg
PMC3884174_01_cde-0005-0259-g03.jpg
F3
The case with multiple metastases was treated with 21 Gy of radiation therapy and chemotherapy as described above, but nevertheless failed to show a clinical response; the patient experienced local recurrence on the periphery of the skin graft (fig. 3a) and multiple bone metastases afterwards. Although the recurrent lesion was surgically resected again, the histopathology demonstrated intradermal proliferation of EPC cells (fig. 3b), and the patient succumbed to his condition 8 months after the resection.