PMC3014791_01
Sections of invaded skin showing prominent infiltration by peripheral natural killer/T-cell lymphoma cells (hematoxylin and eosin, x400).
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fig1
Both the sections of invaded skin and lymph nodes histologically indicated peripheral NK/TCL of the nasal type with strongly positive CD56, CD43, CD3 and Ki67, but negative CD20, CD30, Bcl-2, and perforin by immunohistochemistry (Figures 1 and 2).
Sections of invaded skin and lymph nodes displaying strongly positive CD3 (cytoplasmic) (a), CD56 (b), CD43 (c), and Ki67 (d), but negative CD20 (e), CD30 (f), Bcl-2 (g), and perforin (h) by immunohistochemistry (x400).
CRIM2010-403237.002.jpg
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fig2
Both the sections of invaded skin and lymph nodes histologically indicated peripheral NK/TCL of the nasal type with strongly positive CD56, CD43, CD3 and Ki67, but negative CD20, CD30, Bcl-2, and perforin by immunohistochemistry (Figures 1 and 2).
Rapid remission in left leg lesions by bortezomib plus CHOP chemotherapy. (a) Day 0 in the first course. (b) Day 5 in the first course. (c) Day 8 in the first course. (d) Day 5 after the first course. (e) Day 7 after the second course. (f) Day 7 after the fourth course.
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fig3
She reached CR with mild brown pigmentation just after two courses of chemotherapy and received another two courses as consolidation (Figure 3).