PMC9022114_01
Contrast-enhanced magnetic resonance (MR) of a mass on the pancreatic neck-body. (A) T1W Cross-sections MR in arterial phase. (B) T1W Cross-sections MR in portal phase. (C) T2W Axial MR in arterial phase.
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F1
Contrast-enhanced magnetic resonance (MR) revealed an 8.2 x 5.7 cm circular confounding signal mass on the pancreatic neck (Figure 1).
A slightly weaker echogenic mass on ultrasound. (A) Two-dimensional ultrasonography. (B) contrast-enhanced ultrasound (CEUS) in arterial phase. (C) CEUS in parenchymal phase.
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F2
Two-dimensional ultrasonography revealed a slightly weaker echogenic mass of approximately 8.6 x 6.4 cm in the pancreatic neck body area, with clear boundaries, clear capsules, heterogeneous internal echoes, and small hypoechoic areas (Figure 2A). CEUS considered mostly SPT (Figures 2B,C).
Photomicrograph of pancreatic neurofibroma. Collagen fibers contain a large number of spindle cells (H&E stain, x100).
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F3
Histopathology found that the tumor was mainly composed of spindle cells with cytologically bland wavy nuclei in a collagenous matrix (Figure 3).
Photomicrograph of pancreatic neurofibroma. (A) Immunohistochemical staining [CD34(+)]. (B) Immunohistochemical staining [S100(+)].
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F4
CD34 (+), and Ki67 (+2%) (Figures 4A,B). Combined with histological morphology and immunohistochemical results, it was considered a peripheral nerve tumor, and its subtype was consistent with solitary neurofibroma.