PMC7735430_01
The biphasic lesion is composed of large, irregularly branching ducts and smaller glands in a lobular arrangement surrounded by hypocellular, dense collagenous stroma. The periphery of the lesion appears well-circumscribed but unencapsulated. (Image 4x)
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The final pathology report was consistent with benign fibroadenoma, and the surgical pathologist reported that there was no normal breast tissue, which implies that this is likely a fibroadenoma arising from anogenital mammary-like glands rather than arising from ectopic breast tissue (Figures 1 and 2).
Both the stromal and epithelial components are cytologically bland and lack mitoses. Scattered myoepithelial cells with clear cytoplasm easily are identified surrounding the ducts and glands. The histologic appearance is identical to fibroadenoma of the breast. (Image 20x)
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The final pathology report was consistent with benign fibroadenoma, and the surgical pathologist reported that there was no normal breast tissue, which implies that this is likely a fibroadenoma arising from anogenital mammary-like glands rather than arising from ectopic breast tissue (Figures 1 and 2).