PMC3938367_01
A: Loss of the distal end of the 5th toe of the right foot and
partial onycholysis; B: Fusiform cell proliferation in a myxoid
stroma (HE, x100); C: Fusiform cells show cytoplasmic positivity to
CD34 (PAP, x200); D: Image after excision. The macroscopic part of
the tumor along with nail apparatus can be seen
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Upon examination, the distal end of the 5th toe presented a central ulcer with blood remains and partial onycholysis (Figure 1A). Histological results showed neoplastic dermal proliferation of fusiform cells without any relevant atypia, immersed in a myxoid stroma with collagenized areas and a prominent vascular weave (Figure 1B). Immunohistochemical studies reported positive results for CD34 and negative for S100, AME and AML (Figure 1C). The tumor was extirpated with wide margins, including the nail matrix, respecting the distal phalanx (Figure 1D).