PMC3292829_01
Axial contrast enhanced CT scan of the chest reveales the presence of a smooth edged 18 mm pulmonary lesion in the left inferior hilum.
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F1
The chest X-ray and the subsequent enhanced chest computed tomography (CT) scan revealed the presence of a well-circumscribed, ovular, smooth edged, dense pulmonary lesion in the left inferior hilum (Figure 1).
Histolpathological findings. Figure 2A and B: Haematoxilin-eosin stain of the lesion at 4x and 10x original magnification respectively. Figure 2C: Strong immunoreactivity in epithelial cuboidal cells for TTF-1 antibody (10x original magnification).
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F2
Histologically, the mass was well demarcated (Figure 2a) and composed of a network of cystic spaces lined with simple epithelial cuboidal type II pneumocytes cells without atypia that contain stroma ranging from thin inconspicuous strands of connective tissue to broad spectrum of spindle cells sometimes in a myxoid matrix (Figure 2b). The immunohistochemical profile in the epithelial component was positive for thyroid transcription factor (TTF-1) (Figure 2c) and negative for myogenin, surfactant and cytokeratins.