PMC5910501_01
Case 1. A: Ulceration shows violaceous undermined border B: Ulceration at site of venipuncture C: Histopathology at low magnification shows superficial and deep suppurative inflammation extending to deep subcutaneous tissue D: Histopathology at high magnification shows abundant neutrophils.
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Patient was managed with wound care, systemic steroids, and cyclosporine. Progression of ulcerations was quickly halted following initiation of treatment (Fig. 1).
PMC5910501_02
Case 2. A: Ulceration at stump site shows undermined erythematous border and a cribriform base B: Histopathology at low magnification shows superficial and deep suppurative inflammation extending to subcutaneous tissue C: Histopathology at high magnification shows mainly neutrophils and leukocytoclastic vasculitis.
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The size of ulcer decreased gradually during treatment (Fig. 2).
PMC5910501_03
Case 3. A: Ulceration at previous surgical sites show undermined erythematous ulcers with surrounding violaceous, blue grey erythema B: Histopathology at low magnification shows suppurative inflammation extending into the deep subcutaneous tissue C: Histopathology at high magnification shows sheets of neutrophils with focal necrosis and hemorrhage.
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Patient was successfully managed with Adalimumab for both his PG and IBD (Fig. 3).