PMC5966680_01
((a), (b)) Macroscopic features of the specimen with the stenotic area and mesalamine pills accumulation. ((c), (d)) CD with typical granuloma ((c) EE 4 HPF) and lymphoid aggregates ((d) EE 10 HPF). ((e)-(h)) Endometriosis focus ((e) EE 4 HPF; (f) EE 10 HPF) and immunohistochemical staining for estrogen ((g) 10 HPF) and progesterone ((h) 10 HPF).
CRIGM2018-1509167.003.jpg
PMC5966680_01_CRIGM2018-1509167.003.jpg
fig3
The macroscopical appearance of the surgical specimen revealed a stenosis of the terminal ileum at the level of ileocecal valve with accumulation of pills of mesalamine in the distal ileum (Figures 3(a) and 3(b)). The histological evaluation revealed a typical CD with sectorial erosions, ulcerations, and inflammation of the mucosa with multiple lymphoid aggregates in the submucosa, muscularis propria, and serosa together with foci of endometriosis (estrogen and progesteron positive immunostain) (Figures 3(c)-3(h)).