PMC3687169_01
Computed tomography scan-neoplastic lesion of left parotid gland (arrows)
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F1
Computed tomography (CT) scan showed centrally necrotic rounded mass lesion arising from parotid gland [Figure 1].
(a) Tumor with normal parotid gland (H and E, x100), (b) Tumor showing spindle shaped cells arranged in long and short fascicles (H and E, x100), (c) Tumor showing chondroid differentiation in some areas (H and E, x100). (d) High power view of the tumor cells showing pleomorphism. tumor giant cells and abnormal mitosis (H and E, x400)
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F2
Histopathological examination revealed a tumor composed of spindle shaped cells with elongated hyperchromatic nuclei, arranged in long and short fascicles [Figure 2].
Immunohistochemical staining showing (a) Positivity of tumor cells with S-100 and negativity for (b) Pan cytokeratin, (c) HMB 45, and (d) Vimentin (x400)
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F3
Immunohistochemically, the tumor cells showed diffuse and strong positivity for S-100, (Dako), however, were negative for Pan-cytokeratin (Dako, AE1/AE3), Desmin (Dako, D33), and Human Melanoma Black (HMB) 45 (Dako) [Figure 3] and Vimentin (Dako).
Post-operative photograph showing (a) Location of excised tumor, (b) Patient with post-operative facial palsy
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F4