PMC10105550_01
Chest CT scan during admission. (a) The chest CT images on April 20, 2021 showed nodules in the upper lobes of the lungs and a little halo sign. (b) The chest CT images on April 28, 2021 showed a range of flocculent high-density shadow increased in the lobes of bilateral pulmonary, peripheral halo sign diffused, and the lesions progressed in contrast to the images on April 20, 2021, especially the whole upper lobe of the left lung showed ground-glass opacity. (c) The chest CT images on May 5, 2021 showed that lesions are mostly absorbed and pneumonia was significantly improved.
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Chest computed tomography (CT) scan showed double pneumonia and bilateral localized thickening (Figure 1a). Re-examination of chest CT showed double pneumonia with localized thickening of bilateral pleura, with increased range of flocculent high-density shadow in lobes of bilateral pulmonary as compared to the initial examination (Figure 1b). After 5 days, a re-examination of chest CT revealed that lesions were mostly absorbed and pneumonia was significantly improved (Figure 1c).
Reads count, coverage, and average depth results of Chlamydia psittaci suggested by metagenome next-generation sequencing in this case.
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BALF analysis with mNGS (Simcere Diagnostic, Nanjing, China) reported sequence reads of Burkholderia contaminans complex (3488), Stenotrophomonas maltophilia (145), Pseudomonas aeruginosa (22), Candida albicans (441), Aspergillus flavus (4), and C. psittaci (13) (Figure 2).
The disease progression of patient and treatment procedure. Abbreviations: CT, computed tomography; mNGS, metagenome next-generation sequencing; T, temperature.
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The disease progression of the patient and treatment procedure are shown in Figure 3.