PMC4657225_01
B-scan of both eyes. (A) Normal eye, OD, (B) longitudinal, and (C) transverse of OS showing diffuse choroidal thickening, and internal reflectivity representing a diffuse choroidal hemangioma with peripheral retinal detachment.
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Fig1
OD and 0.45 OS. Ocular ultrasonography revealed a slightly irregular, diffuse, dome-shaped mass 3.5 mm thick OS with internal reflectivity, consistent with a diffuse choroidal hemangioma; additionally, a thin, highly reflective membrane suggestive of an overlying exudative retinal detachment was present (Figure 1).
SD-OCT with corresponding multicolor images. (A) SD-OCT with corresponding multicolor image of subretinal fluid associated with hemangioma before treatment. (B) SD-OCT with corresponding multicolor image of subretinal fluid associated with hemangioma after first intravitreal Avastin treatment, (C) SD-OCT with corresponding multicolor image of subretinal fluid associated with hemangioma after four intravitreal Avastin treatments.
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Fig2
Spectral-domain optical coherence tomography (SD-OCT) confirmed the presence of subretinal fluid (Figure 2A). The patient was treated with intravitreal bevacizumab, 1.25 mg in 0.05 mL; six weeks later, SD-OCT showed a marked decrease of the subretinal fluid (Figure 2B). Resolution of the exudative retinal detachment can be seen in Figure 2C.
Fluorescein angiography of the left eye. (A) Marked central hyperfluorescence in the venous phase, and (B) late phase showing increased hyperfluorescence indication leakage.
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Fig3
Fluorescein angiography (Figure 3) showed early hyperfluorescence as well as late phase leakge, which is consistent with an exudative retinal detachment.