PMC2879604_01
(a) Disseminated whitish macules on the front and the back of the trunk. (b) Nonscaly macules in detail on the back.
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fig1
Skin findings consist of symmetrically distributed hypopigmented, nummular, partial confluent, nonscaly macules on trunk and less pronounced on proximal parts of arms and legs, as well as sparing head and neck (Figures 1(a), 1(b)).
Electron microscopy of non-affected skin. Left (8:300x): numerous melanosomes aggregated in big clusters and disseminated melanosomes. Right detail (49:800x): Granular melanosomes mostly grade III-IV.
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fig2
Upon electron microscopic comparison of type and distribution patterns of melanosomes in affected (Figure 3) and nonaffected epidermis (Figure 2), we found those in macules of PMH to be more aggregated and single melanosomes were smaller.
Electron microscopy of affected skin. Left (8:300x): sparse melanosomes aggregated in small clusters and some solitary. Right detail (49:800x): Melanosomes mostly grade I-II, few grade III and less granular.
DRP2009-607682.003.jpg
PMC2879604_01_DRP2009-607682.003.jpg
fig3
Upon electron microscopic comparison of type and distribution patterns of melanosomes in affected (Figure 3) and nonaffected epidermis (Figure 2), we found those in macules of PMH to be more aggregated and single melanosomes were smaller.