PMC5676375_01
Large, ulcerated mass in the sigmoid colon seen during colonoscopy.
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fig1
Colonoscopy showed a 2 cm, nonobstructing, ulcerated mass in the sigmoid colon (Figure 1).
Hematoxylin and eosin staining shows fragments of large atypical cells with focal gland formation consistent with an adenocarcinoma.
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fig2
Biopsies of the sigmoid mass were consistent with an adenocarcinoma (Figure 2).
Cytokeratin 7 (CK7) typically stains positive (dark brown) in carcinomas of epithelial origin including endometrial cancer.
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fig3
Normal colon mucosa on the left with the margin of tumor on the right containing large, atypical cells consistent with adenocarcinoma.
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fig4
Histology of the surgical specimen confirmed metastatic endometrioid adenocarcinoma in the small bowel and sigmoid tumors (Figure 4).