PMC3504227_01
Serum creatinine levels and related events during the course of renal transplantation.
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fig1
The timeline of clinical events is shown in Figure 1.
Biopsy Shows calcium oxalate crystal deposition in the renal tubules under polarized light microscopy (1st biopsy performed during 3rd week of transplantation).
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fig2
The biopsy was significant for acute tubular necrosis (ATN, confirmed by kidney injury molecule-1 immunostain) and CaOx crystal deposition with no evidence of rejection (Figure 2).
(a) shows widespread massive aggregate of CaOx crystals in the renal collecting system extending into the parenchyma seen under polarized light. (b) shows a region of (a) under high power showing accumulation of polygonal crystals with multicolored birefringence under polarized light. AON: acute oxalate nephropathy, CaOx: calcium oxalate.
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fig3
The explant showed extensive aggregates of CaOx crystals (multicolored birefringence polygonal crystals under polarized light as shown in Figures 3(a) and 3(b)) in the renal collecting system extending to the parenchyma.