PMC6415289_01
Preoperative image of MASC tumor right palate.
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The lesion was roughly 2.0 cm x 1.0 cm in size (Figure 1).
(a) MRI coronal T1image with MASC tumor. (b) MRI sagittal T1 image with MASC tumor.
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The CT showed a focal area of bone thinning and focal dehiscence at the floor of the right maxillary sinus without evidence for frank tumor extension into the sinus (Figures 2(a) and 2(b)).
MASC tumor with PAS stain and diastase (magnification x200).
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The secretory material from the glandular spaces was noted to be periodic acid Schiff- (PAS-) positive and diastase-resistant (Figure 3).
MASC tumor comprised of cells forming microcystic and glandular spaces containing eosinophilic homogenous material (H&E, magnification x200).
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The tumor cells had eosinophilic granular cytoplasm with low-grade vesicular nuclei and visible nucleoli (Figures 4 and 5).
MASC tumor cells with eosinophilic granular cytoplasm and low-grade vesicular nuclei (H&E, magnification x400).
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The tumor cells had eosinophilic granular cytoplasm with low-grade vesicular nuclei and visible nucleoli (Figures 4 and 5).
Mammaglobin highlights the neoplastic cells and secretions (magnification x400).
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The tumor was also diffusely positive for both mammaglobin and S100, supportive for the diagnosis of MASC (Figures 6 and 7).
S100 protein staining is present in the tumor cells (magnification x400).
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The tumor was also diffusely positive for both mammaglobin and S100, supportive for the diagnosis of MASC (Figures 6 and 7).
Postoperative image of surgical site healing by secondary intention.
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The surgical site was allowed to heal by secondary intention with granulation tissue (Figure 8).
Surgical site at 36 months. No evidence of recurrence.
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At his most recent follow-up, 36 months after surgery, the patient was free of tumor (Figure 9).