PMC7145165_01
Endoscopic imaging revealing a friable, ulcerated stricture in the distal transverse colon 40 cm from the anal verge representing colonic squamous cell carcinoma.
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F1
During the colonoscopy, the patient was found to have an 8-cm long ulcerated, friable stricture in the distal transverse colon 40 cm from the anal verge (Figure 1).
Colon biopsy showing (A) highly proliferative, malignant infiltration of the colonic wall mucosa with hematoxylin & eosin stain, (B) with positive p63 staining in the nuclei of malignant squamous cells, (C) positive p40 staining in the nuclei of malignant squamous cells, and (D) positive cytokeratin 5/6 staining in the cytoplasm of malignant squamous cells.
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F2
Pathology resulted in SCC with positive immunostaining for markers p63, p40, and cytokeratin 5/6 (Figure 2).