PMC3099431_01
A) Eighteen hours after administration of Radix Astragali. Edematous erythema with a sensation of heat at the hands and feet. Upper panel: the palm, Middle panel: the back of hands, Lower panel: feet. B) Forty-eight hours after discontinuation of Radix Astragali intake. Edematous erythema had almost disappeared.
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However, about 18 hours after he ingested the full day's dose (twice a day) including Radix Astragali, erhythema with swelling of the bilateral hands and feet appeared (Fig. 1A). Administration of the altered formula was discontinued and 2 days later, his symptoms had almost disappeared (Fig. 1B) and the serum CRP level was <0.1 mg/dl.
PMC3099431_02