PMC4050287_01
Peripheral smear showing hypogranular, hypolobate neutrobils and leukemic blasts (1a) and bone marrow aspirate cell block showing strong expression of c-kit on leukemic blasts (1b).
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Majority of circulating neutrophils showed dysplastic features in the form of hypo-lobate nuclei and hypo-granular cytoplasm (Fig. 1a).
Flow cytometry plots. Leukemic blasts express CD45 and show low side scattter (a). They express CD34 and CD117 (b). They also express CD7, MPO, cytoplasmic CD3 and TDT (c-f).
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Flow cytometry showed the blasts to express CD117, cytoplasmic CD3, CD2, CD7 and myeloperoxidase (MPO) (Fig. 2a-f).