PMC3290853_01
Proliferative and exudative acute GN. HE. x200.
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F1
Light-microscopically, the renal biopsy revealed global sclerosis in 1 of 6 glomeruli; in the other glomeruli architecture was preserved: they were voluminous, hypercellular and exudative, with numerous polymorphonuclear leukocytes (fig. 1).
Foci of neoplastic infiltration of plasma cells (MM).
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F2
Following nephrectomy, histopathological analysis of the left kidney revealed multifocal MM infiltration with the following findings: interstitial groups of well-differentiated neoplastic plasma cells; presence of a large number of intratubular hyaline casts; multifocal tubular dilatation, and diffuse endocapillary proliferative GN with fuchsinophilic subepithelial deposits, suggesting the presence of 'humps' (fig. 2).