PMC9922532_01
Representative gel image showing RT-PCR for DNAJB1-PRKACA fusion transcripts; the DNAJB1-PRKACA fusion transcript is detected only in the FLHCC sample. RT-PCR: real-time polymerase chain reaction; FLHCC: fibrolamellar hepatocellular carcinoma; adeno: adenomyomatosis
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FIG1
ODC expression on fibrolamellar carcinoma and normal liver samples using 20 and 50 ng of RNA in RT-PCR reactions. Control: normal liver; Fibro: fibrolamellar carcinoma; OCD: ornithine decarboxylase; RT-PCR: real-time polymerase chain reaction
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FIG2
The relative expression versus Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) of AURKA in FLHCC and adenomyomatosis samples presented increased expression of AURKA, c-Myc, and ornithine decarboxylase (Figure 2) when compared to normal liver.
OTC expression on fibrolamellar carcinoma and normal liver samples using 20 and 50 ng of RNA in RT-PCR reactions. Control: normal liver; Fibro: fibrolamellar carcinoma; OTC: ornithine transcarbamylase; RT-PCR: real-time polymerase chain
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FIG3
On the other hand, ornithine transcarbamylase was decreased in FLHCC and adenomyomatosis when compared to a non-tumor liver (Figure 3).