PMC7845154_01
Positron emission tomography/computerised tomography demonstrating elevated tracer uptake in an 8.4-mm left level IV lymph node (red arrow).
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Histology from left neck dissection showing metastasis of poorly differentiated carcinoma in lymph node (40X magnification).. (
a) Atypical cells with pleomorphic nuclei demonstrated Hematoxylin and Eosin stain. (
b) Immunohistochemistry for CK20 with characteristic cytoplasmic and nuclear staining. (
c) Immunohistochemistry for CDX-2. (
d) Intracellular mucus detected on special stain (ABPAS) confirming glandular (adenocarcinoma). ABPAS is an Alcian Blue stain which demonstrates intra and extracellular mucous.
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Immunohistochemical analysis confirmed an intestinal origin ( Figure 2).