PMC6702890_01
A 66-year-old female with abnormal screening mammogram showing a mixed density circumscribed mass with areas of fat density in the left breast at the 3 o'clock position (arrow).
JCIS-9-10-g001.jpg
PMC6702890_01_JCIS-9-10-g001.jpg
F1
A 66-year old female presented for a screening mammogram at the outside hospital which showed a 2.8 cm mixed density well-circumscribed mass with subtle areas of fat density in the left breast at the 3 o'clock position [Figure 1].
A 66-year-old female with external ultrasound showing well-circumscribed hyperechoic mass in the left breast.
JCIS-9-10-g002.jpg
PMC6702890_01_JCIS-9-10-g002.jpg
F2
Diagnostic ultrasound was performed and showed a well-circumscribed predominantly hyperechoic mass [Figure 2].
A 66-year-old female with breast magnetic resonance imaging shows heterogeneous mass with areas of T1 hyperintensity (a) suppressing on short-tau inversion recovery (b) in the left breast. Postcontrast maximum intensity projection image shows irregularly enhancing mass (c).
JCIS-9-10-g003.jpg
PMC6702890_01_JCIS-9-10-g003.jpg
F3
This also showed areas of T1 hyperintensity suppressing on short-tau inversion recovery, likely composed of fatty tissue [Figure 3].
A 66-year-old female with malignant phyllodes tumor on biopsy of the left breast mass with positron emission tomography-computed tomography scan showing area of mild uptake in left breast (arrow) with no lymphadenopathy or metastasis.
JCIS-9-10-g004.jpg
PMC6702890_01_JCIS-9-10-g004.jpg
F4
PET scan was also performed to evaluate distant metastases and showed the area of mildly increased fluorodeoxyglucose uptake in the left breast with no areas of lymphadenopathy or avid distant metastasis [Figure 4].
A 66-year-old female with biopsy of the breast mass. Tumor pathology slides showing a fibroepithelial lesion showing "leaf-like" architecture (arrows) of the phyllodes tumor (H and E, x4).
JCIS-9-10-g005.jpg
PMC6702890_01_JCIS-9-10-g005.jpg
F5
Resection specimen [Figures 5 and 6] showed a fibroepithelial lesion with increased stromal mitotic rate (up to 10 mitoses per 10 high-power fields [HPFs]) and heterologous liposarcomatous differentiation.
A 66-year-old female with biopsy of the breast mass. Tumor pathology slides showing heterologous liposarcomatous differentiation with variably sized, hyperchromatic, atypical adipocytes (arrow), numerous lipoblasts and high mitotic rate (H and E, x10).
JCIS-9-10-g006.jpg
PMC6702890_01_JCIS-9-10-g006.jpg
F6
Resection specimen [Figures 5 and 6] showed a fibroepithelial lesion with increased stromal mitotic rate (up to 10 mitoses per 10 high-power fields [HPFs]) and heterologous liposarcomatous differentiation.