PMC1334209_01
shows plasma platinum levels measured from day 3 to day 13 after the last cisplatin administration in mg platinum/kg plasma. Black arrows indicate the time of the two plasmaphereses, the black rhomboids the extent of platinum levels in mg/kg plasma.
1471-2407-6-1-1.jpg
PMC1334209_01_1471-2407-6-1-1.jpg
F1
The plasma levels of total platinum showed a marked decline after plasma exchange at first, followed by a small rise and then a constant decline afterwards as demonstrated in Figure 1.
demonstrates the complete restitution of the hearing curves from 0.75 kilohertz to 6 kilohertz in the audiograms of the patient performed at three different times. On the x-axis the frequency in kilohertz is shown, the y-axis indicates the loudness in decibel. The arrows point at the changes in the curves.
1471-2407-6-1-2.jpg
PMC1334209_01_1471-2407-6-1-2.jpg
F2
She recovered completely from all toxicities including hearing loss which was proven clinically and by audiometry (Figure 2) except for a subclinical renal impairment remaining from the acute renal failure (Table2).