PMC3808792_01
Focal and segmental glomerulosclerosis and mild to moderate interstitial fibrosis. Trichrome stain. x400.
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F1
Optic microscopy revealed focal and segmental glomerulosclerosis (fig. 1).
Advanced focal and segmental glomerulosclerosis, podocyte edema and vacuolization. Masson's trichrome stain. x200.
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F2
The kidney biopsy was consistent with secondary focal and segmental glomerulosclerosis and suggested Fabry's disease (fig. 2).
Electron microscopy depicting electron-dense laminated lipids, also known as Zebra bodies, in this case in the cytoplasm of a podocyte. x20,000.
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F3
Electron microscopy and genetic studies confirmed the diagnosis (fig. 3).