PMC5030413_01
Axial T2-weighted brain MRI (a) shows increased signal in the splenium of corpus callosum (arrow in (a)). Diffusion weighted (DWI) (b) and ADC-map (c) images show restricted diffusion in the involved areas of corpus callosum (arrows in (a) and (b)) that is consistent with necrosis. Sagittal T2-weighted image (d) shows sparing of the periphery of corpus callosum.
CRINM2016-5848572.001.jpg
PMC5030413_01_CRINM2016-5848572.001.jpg
fig1
T2/FLAIR signal was seen in the splenium of corpus callosum (Figure 1(a)). The lesion showed restricted diffusion on diffusion weighted images (DWI) (Figures 1(b) and 1(c)). The periphery of the splenium was spared (Figure 1(d)). The findings were characteristic of Marchiafava-Bignami and explained the dysphagia and mood disorders.