PMC9871736_01
Transverse colon. A) H&E, 200 x, necrotic colon with purulent exudate. B) GMS, 200 x, purulent exudate contains fungal elements morphologically compatible with Candida species.
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PMC9871736_01_gr1.jpg
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GMS stain revealed fungal elements morphologically compatible with Candida species (Fig. 1).
Resected jejunal anastomosis A) H&E, 20 x, marked active enteritis with mucosal ulceration and patchy necrosis. B) H&E, 200 x, Necrotic areas demonstrate ribbon-like fungal hyphal forms with wide angle branching, morphologically consistent with Mucormycetes species. C) GMS, 200 x, fungal hyphal forms are outlined by GMS. D) PASF, 200 x, fungal hyphal forms are outlined by PASF.
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PMC9871736_01_gr2.jpg
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Microscopic examination of the jejunal tissue revealed marked active enteritis with mucosal ulceration and necrosis and ribbon-like fungal hyphal forms with wide angle branching, morphologically consistent with Mucormycetes species (Fig. 2).
Resected jejunal anastomosis A) H&E, 200 x, vascular invasion of mucormycosis with obliteration of vasculature. B) H&E, 200 x, tissue and vascular invasion of Mucormycetes with associated intravascular thrombosis and ischemic tissue damage.
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Vascular invasion and associated vascular thrombosis and ischemia were present (Fig. 3). The resected ileum demonstrated acute and chronic ileitis with purulent serosal exudate and focal wide-branching ribbon-like forms consistent with Mucormycetes species, as well as yeast forms consistent with Candida (Fig. 3).