PMC6968569_01
Aspiration of intracapsular seroma fluid after explantation of the intact capsule containing the implant.
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We performed a removal of the complete capsule containing the implant, acquiring the intracapsular seroma fluid by aspiration after explantation ( Figures 1-3).
Intracapsular seroma fluid.
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We performed a removal of the complete capsule containing the implant, acquiring the intracapsular seroma fluid by aspiration after explantation ( Figures 1-3).
Inner surface of the capsule (left) and intact mammary implant (right). The histopathological analysis including immunohistochemistry showed conglomerates of fibrin deposits and CD30 positive and ALK negative tumour cells on the inner surface of the capsule (black arrows).
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We performed a removal of the complete capsule containing the implant, acquiring the intracapsular seroma fluid by aspiration after explantation ( Figures 1-3).
Histological image of the fibrinous implant capsule and the fibrinous exudate containing anaplastic tumour cells on the inner surface of the capsule. Black arrows = anaplastic tumour cells.
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Figure 4; black arrows indicating anaplastic tumour cells), thus confirming the diagnosis of an in situ BIA-ALCL. Figure 5 (Hematoxylin and eosin stain) and Figure 6 (CD30 stain) show the neoplastic seroma fluid, which exhibits numerous highly atypical large anaplastic tumour cells characteristic for anaplastic large-cell lymphoma (ALCL) as well as scant inflammatory cells, predominantly lymphocytes (black arrows = anaplastic tumour cells; grey arrows = lymphocytes).
Cytological image of the neoplastic seroma fluid containing numerous highly atypical large anaplastic tumour cells characteristic for anaplastic large-cell lymphoma (ALCL) as well as scant inflammatory cells, predominantly lymphocytes (Hematoxylin and eosin stain; black arrows = anaplastic tumour cells; grey arrows = lymphocytes).
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Figure 4; black arrows indicating anaplastic tumour cells), thus confirming the diagnosis of an in situ BIA-ALCL. Figure 5 (Hematoxylin and eosin stain) and Figure 6 (CD30 stain) show the neoplastic seroma fluid, which exhibits numerous highly atypical large anaplastic tumour cells characteristic for anaplastic large-cell lymphoma (ALCL) as well as scant inflammatory cells, predominantly lymphocytes (black arrows = anaplastic tumour cells; grey arrows = lymphocytes).
Cytological image of the neoplastic seroma fluid containing numerous highly atypical large anaplastic tumour cells characteristic for anaplastic large-cell lymphoma (ALCL) as well as scant inflammatory cells, predominantly lymphocytes (CD30 stain; black arrows = anaplastic tumour cells; grey arrows = lymphocytes).
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Figure 4; black arrows indicating anaplastic tumour cells), thus confirming the diagnosis of an in situ BIA-ALCL. Figure 5 (Hematoxylin and eosin stain) and Figure 6 (CD30 stain) show the neoplastic seroma fluid, which exhibits numerous highly atypical large anaplastic tumour cells characteristic for anaplastic large-cell lymphoma (ALCL) as well as scant inflammatory cells, predominantly lymphocytes (black arrows = anaplastic tumour cells; grey arrows = lymphocytes).