PMC4357673_01
a Nodules on the dorsum of the foot (blue arrows) before treatment with intralesional doxorubicin. b The same lesions (red arrows) 2 weeks after the first injection with intralesional doxorubicin. c After over a year from the beginning of treatment, only some minimal scarring (yellow arrow) was identifiable.
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F1
More recently he developed, simultaneously, a crop of 5 nodules and a large plaque of KS 5.5 cm in diameter on the dorsum of the right foot with extension to the interdigital spaces and toes (fig. 1a, fig. 2a). We observed skin necrosis in some well-delimited areas following each injection (fig. 1b), associated with mild to moderate pain which was well controlled with paracetamol 1,000 mg twice daily. The patient has not developed any new lesions for almost 18 months and continues to remain clear (fig. 1c, fig. 2b).