PMC7784608_01
Evolution of TBSA burn between time of admission and the final TBSA evaluation that required surgery, for patient 1 (A) and patient 2 (B), respectively. Hatched areas for patient 2 correspond to the body zones were considered as second-degree intermediate, and where PBBs were applied in order to help the wounds to evolve favorably toward spontaneous healing. It is worth mentioning that a third-degree burn and second deep degree burns are treated similarly from a surgical point of view (pink zones), i.e., both need debridement and skin grafting as the deep burns cannot heal spontaneously. Please note that for both patients, temporary covers (either cadaveric or PBBs) were applied at day 7, while nowadays we aim to cover after the first debridement around days 4 to 5 (as stated in the surgical pathway in Fig. 1).. ICU: intensive care unit; PBBs: Progenitor Biological Bandages; TBSA: total body surface area.
10.1177_0963689720973642-fig2.jpg
PMC7784608_02_10.1177_0963689720973642-fig2.jpg
fig2-0963689720973642
TBSA deep and intermediate burns after an explosion of solvents in his workshop. The burns were mainly of the face and neck sparing the groin and both feet as for patient 1 (Fig. 2B). TBSA of CEA and the rest with autologous skin graft), with a total of 15 surgical interventions. The final evaluation of deep burns was evaluated at 75% TBSA versus 81% TBSA at admission (Fig. 2B), because several body zones of second intermediate burns (chest, abdomen, back, thighs, and legs) healed by themselves. These zones received the application of Biological Bandages (Fig. 3), which when compared to past experience were thought to stimulate these intermediate-degree burns toward a spontaneous healing of particular body regions (Fig. 4).
PMC7784608_02
Evolution of TBSA burn between time of admission and the final TBSA evaluation that required surgery, for patient 1 (A) and patient 2 (B), respectively. Hatched areas for patient 2 correspond to the body zones were considered as second-degree intermediate, and where PBBs were applied in order to help the wounds to evolve favorably toward spontaneous healing. It is worth mentioning that a third-degree burn and second deep degree burns are treated similarly from a surgical point of view (pink zones), i.e., both need debridement and skin grafting as the deep burns cannot heal spontaneously. Please note that for both patients, temporary covers (either cadaveric or PBBs) were applied at day 7, while nowadays we aim to cover after the first debridement around days 4 to 5 (as stated in the surgical pathway in Fig. 1).. ICU: intensive care unit; PBBs: Progenitor Biological Bandages; TBSA: total body surface area.
10.1177_0963689720973642-fig2.jpg
PMC7784608_02_10.1177_0963689720973642-fig2.jpg
fig2-0963689720973642
TBSA deep and intermediate burns after an explosion of solvents in his workshop. The burns were mainly of the face and neck sparing the groin and both feet as for patient 1 (Fig. 2B). TBSA of CEA and the rest with autologous skin graft), with a total of 15 surgical interventions. The final evaluation of deep burns was evaluated at 75% TBSA versus 81% TBSA at admission (Fig. 2B), because several body zones of second intermediate burns (chest, abdomen, back, thighs, and legs) healed by themselves. These zones received the application of Biological Bandages (Fig. 3), which when compared to past experience were thought to stimulate these intermediate-degree burns toward a spontaneous healing of particular body regions (Fig. 4).
Summary over time of the main surgical interventions (and their respective zone) for both patients, including days of debridement, grafting types and zone, the type of temporary cover (cadaveric or Biological Bandages), as well as the use of skin substitute or PRP. The table is organized by rows of 5 days, each day represented by a single square: gray squares are days without any surgical interventions, and split squares correspond to several surgical interventions per day, with each intervention identified by its color code. Acronyms of the grafting types: CDEA: cultured dermal-epithelial autograft; CEA: cultured epithelial autograft; PRP: platelet-rich plasma; STSG: split-thickness skin autograft.
10.1177_0963689720973642-fig3.jpg
PMC7784608_02_10.1177_0963689720973642-fig3.jpg
fig3-0963689720973642
TBSA of CEA and the rest with autologous skin graft), with a total of 15 surgical interventions. The final evaluation of deep burns was evaluated at 75% TBSA versus 81% TBSA at admission (Fig. 2B), because several body zones of second intermediate burns (chest, abdomen, back, thighs, and legs) healed by themselves. These zones received the application of Biological Bandages (Fig. 3), which when compared to past experience were thought to stimulate these intermediate-degree burns toward a spontaneous healing of particular body regions (Fig. 4). A summary over time of the main surgical interventions and the corresponding body regions is shown for both patients in Fig. 3.