PMC5841062_01
(a) T2 sequence demonstrating "concentric" target sign with concentric alternating hypointense and hyperintense rims. (b) Postcontrast sequence demonstrating "eccentric" target sign with a peripheral rim of enhancement and focal left lateral eccentric enhancing nodule.
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T2 hypointense and hyperintense rims (Figure 1(a)) and postcontrast focal eccentric enhancing nodule that measured 1 cm (Figure 1(b)). These are considered both the "concentric" and "eccentric" target signs, which demonstrate specificity in the setting of cerebral toxoplasmosis.
(a) Toxoplasma cyst demonstrated on H and E stain x40. (b) Toxoplasma cyst confirmed on immunocytochemistry x40.
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Biopsy of the lesion was performed and histopathological analysis confirmed toxoplasma cysts (Figure 2(a)) confirmed on immunohistochemistry (Figure 2(b)).