PMC4334429_01
CT Scan showing tumor invasion of sacrum: left and right surrounding parasacral soft tissue (a), and L4 vertebral body (b).
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A CT scan revealed a large lytic lesion in the pelvis, multiple paraspinal soft tissue masses, parasacral soft tissue masses, and a lytic lesion in the L4 vertebral body (Figures 1(a) and 1(b)), with a chest X-ray showing multiple lung lesions.
Osteosarcoma of pelvis demonstrating hyperchromatic spindle-shaped tumor cells associated with matrix production (a) and osteoid formation (b). Tumor stains positive for beta-hCG (c) (Hematoxylin-eosin [a, b], original magnifications x4 [c], x20 [a-b]).
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Multiple areas of osteoid formation and scattered benign appearing giant cells were noted within the tumor (Figures 2(a) and 2(b)). Additional studies were requested after the patient was found to have high levels of beta-hCG (Figure 2(c)).