PMC6859392_01
Left: Chest X-ray on admission showed a diffuse reticular appearance particularly in both lower lung fields. Right: Chest CT revealed diffuse small patchy shadows and trabecular shadows in both lower lung fields.
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Chest X-ray showed interstitial shadows in both lower lung fields, and computed tomography (CT) showed diffuse patchy and funicular opacities and volume loss predominantly in both lower lung areas (Fig. 1).
Histology of transbronchial lung biopsy specimen: Alveolar tissue with macrophage aggregation and interstitial tissue with mild lymphocytic infiltration were recognized (Hematoxylin and Eosin staining, x400).
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Many alveolar macrophages existed, and mild lymphocytic interstitial inflammation was seen in the transbronchial lung biopsy (TBLB) specimens taken from the right middle and lower lungs (Fig. 2).
Clinical course as well as findings from pulmonary function tests and the number of eosinophils in the peripheral blood. Eos: Eosinophils, VC: vital capacity, %VC: percent vital capacity, FEV1.0: forced expiratory volume in one second, FEV1.0%: forced expiratory volume in one second/forced vital capacity, %DLCO: percent single-breath diffusing capacity of the lung for carbon monoxide
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The patient was discharged from hospital on Day 43; the total hospitalization duration was 23 days (Fig. 3). Pulmonary function test findings also returned to normal, and his single-breath diffusing capacity for carbon monoxide recovered by Day 56 without using steroids or other anti-inflammatory drugs (Fig. 3).