PMC8176117_01
Case presentation of transformation of lung squamous cell carcinoma to small cell lung carcinoma with first-line sintilimab monotherapy. CT, computed tomography; HE, Hematoxylin and Eosin; Syn, synaptophysin; Rx, treatment.
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The patient died of respiratory failure, severe anemia, and severe thrombocytopenia (Figure 1).
PMC8176117_02
Case presentation of transformation of lung squamous cell carcinomas to small cell lung carcinoma with nivolumab. CT, computed tomography; HE, Hematoxylin and Eosin; IHC, immunohistochemical; G, gemcitabine; P, cisplatin; E, etoposide; Syn, synaptophysin; Rx, treatment.
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Finally, he died of the primary disease during the fourth month of follow-up (Figure 2).