PMC5468559_01
The bone marrow core biopsy H&E stain above shows a hypercellular marrow with 100% cellularity and an increase in granulocyte precursors. In addition, an increase in basophils, eosinophils, and an occasional monocyte and blast are also observed. The arrow points to granulocytes comprising most of the marrow.
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fig1
Review of the bone marrow aspirate and biopsy showed a hypercellular marrow with 4% blasts (see Figures 1 and 2).
The bone marrow aspirate shown above demonstrates a "left-shift" in granulopoiesis, especially with a significant increase in myelocytes, promyelocytes, and metamyelocytes.
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fig2
Review of the bone marrow aspirate and biopsy showed a hypercellular marrow with 4% blasts (see Figures 1 and 2).
Karyotype analysis obtained from the bone marrow aspirate with the arrow pointing to the t(9;22) translocation.
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fig3
Figure 3). FISH analysis also confirmed a t(9;22) translocation.