PMC5771873_01
Clinical course from before and to after the onset of HSV pneumonia.
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However, the patient complained of painful dry lips from day 12, and his respiratory status showed rapid deterioration on day 15 (Fig. 1). Noninvasive positive pressure ventilation was also performed for respiratory support, and the patient gradually improved over 1 week (Fig. 1).
Chest CT scan on Day 15. Although the margins of the lungs are relatively maintained, bilateral diffuse ground-glass opacities are observed from apex to base.
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Chest computed tomography (CT) revealed ground-glass opacities in the bilateral lung fields (Fig. 2).
Multinuclear cells with ground-glass-like nuclei can be seen, which are characteristic of HSV infection.
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CMV antigenemia was negative. Cytodiagnosis was performed using a sputum sample obtained on the morning of day 16, revealing multinucleated cells with ground-glass-like nuclei on the same day (Fig. 3).
Chest CT scan on Day 28. There is marked improvement of the bilateral diffuse ground-glass opacities.
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On day 28, repeat chest CT confirmed that there was marked improvement of the interstitial changes (Fig. 4).