PMC4300577_01
(a) Ulceroproliferative growth at the penoscrotal junction and, suprapubic cystostomy (SPC) site with ulcerated, everted mucosal edges; (b) computed tomography scan showing an ill-defined, enhancing mass in the region of posterior urethra infiltrating cavernosae (arrow); (c) Transverse section showing bladder and SPC tract (arrow head)
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F1
The growth extended anteriorly to the penoscrotal junction [Figure 1a]. The abdominal entry site of the suprapubic catheter was ulcerated with rolled out edges and induration [Figure 1a]. CT scan showed an enhancing ill-defined soft tissue density in the region of bulbar urethra infiltrating corpora cavernosa, adjacent skin and subcutaneous tissue [Figure 1b]. Transverse section [Figure 1c] at the level of bladder and suprapubic cystostomy (SPC) tract showed induration surrounding the tract.
(a) Postoperative picture following radical urethrocystoprostatectomy with en-bloc excision of suprapubic cystostomy (SPC) tract and wide local excision of scrotum; (b) H and E, x10 showing primary squamous cell carcinoma (SCC) of urethra with keratin pearls; (c) H and E, x20 showing foci of SCC in the SPC tract
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F2
He underwent a total penile amputation, wide local excision scrotum, radical urethrocystoprostatectomy, ileal conduit diversion, and pelvic lymphadenectomy [Figure 2a]. Histopathological examination showed moderately differentiated SCC of the bulbar urethra [Figure 2b] with 2 right external iliac lymph nodes positive for metastasis. The SPC site was also reported to harbor SCC [Figure 2c].