PMC6626973_01
Abdominal CT showed an 8 x 8 x 4 cm mass (arrowhead) on the cranial side of the bladder in the abdomen.
gr1.jpg
PMC6626973_01_gr1.jpg
fig0005
Computed tomography (CT) showed an 8- x 8- x 4-cm abdominal mass on the cranial side of the bladder, an intra-abdominal lipoma was suspected and observed (Fig. 1).
(a) T2-weighted MRI showed a large, well-defined, low-signal mass measuring 20 x 17 x 7 cm (arrowhead) in the abdomen. (b) The mass was adjacent to another abnormal region measuring 6 x 6 x 5 cm with septae and a capsule (arrow).
gr2.jpg
PMC6626973_01_gr2.jpg
fig0010
A liposarcoma (smaller region) with a lipoma (larger mass) was suspected, and no metastatic lesions were observed (Fig. 2a, b).
(a) A huge yellowish, soft mass with a dark reddish-gray region adjacent to the mass was located under the abdominal wall. (b) The feeder vessel originated from the omental artery.
gr3.jpg
PMC6626973_01_gr3.jpg
fig0015
After ligation of the feeder vessel originating from the omental artery, existing cranial side of the mass, the mass was resected en bloc (Fig. 3a, b).
(a) The resected specimen, including the yellowish mass (yellow arrowhead) and reddish-gray region (red arrowhead), weighed 3750 g and measured 27 x 20 x 10 cm. (b) The cut surface of the tumor was shown. The diagnosis was a well-differentiated liposarcoma in the areas of black arrow and black arrowhead, and a lipoma in the area of white arrow.
gr4.jpg
PMC6626973_01_gr4.jpg
fig0020
The resected specimen, which comprised a yellowish mass and reddish-gray region, weighed 3750 g and measured 27 x 20 x 10 cm (Fig. 4a, b). Histopathological examination showed that within the reddish-gray region (black arrowhead in Fig. 4b), neoplastic spindle cells with atypical nuclei containing condensed chromosomes were present in the septae (Fig. 5a). Fig. 4b), malignant cells were also seen (Fig. 5b). Far from the reddish-gray region in the yellowish mass (white arrow in Fig. 4b), mature adipocytes with uniform nuclei resembling normal fat tissue were observed (Fig. 5c). Immunohistochemical analysis revealed the MDM2+/CDK4+ immunophenotype (black arrowhead and black arrow in Fig. 4b) and the MDM2-/CDK4- immunophenotype (white arrow in Fig. 4b). The diagnosis was a well-differentiated liposarcoma (black arrow and black arrowhead in Fig. 4b) and a lipoma (white arrow in Fig. 4b) based on the histopathological features.