PMC2816343_01
Long PCR analysis of CYP2D6*5. A 3.2 kb product represents the deletion of CYP2 D6 gene in this patient (Lane 1, DNA size marker; lane 2, positive control; lane 3, negative control; lane 4, this case).
jkms-19-750-g001.jpg
PMC2816343_01_jkms-19-750-g001.jpg
F1
The patient was found to have CYP2D6*5/*10B, which results in low CYP2D6 activity (Fig. 1, 2).
Detection of nucleotide changes by sequencing analysis of CYP2D6 gene. This case has CYP2D6*10B allele with C100T (A), C1039T (B), G1661C (C), and G4180C (D) substitution.
jkms-19-750-g002.jpg
PMC2816343_01_jkms-19-750-g002.jpg
F2
The patient was found to have CYP2D6*5/*10B, which results in low CYP2D6 activity (Fig. 1, 2).