PMC5565628_01
EEG performed while awake at 11 years of age.. The EEG showed bilateral diffuse spike-and-wave complexes and diffuse polyspike bursts followed by motion artifacts during a myoclonic seizure.
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His electroencephalogram (EEG) showed bilateral diffuse polyspike-and-wave complexes (Fig. 1).
Clinical course of drugs, seizures and neurological findings in our patient from 7 to 14 years of age.. CBZ, carbamazepine; VPA, valproate; LTG, lamotrigine; LEV, levetiracetam; PB, phenobarbital; CLB, clobazam; PER, perampanel; GTCs, generalized tonic-clonic seizures.
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However, he continued to experience daily myoclonic seizures and weekly GTCs (Fig. 2). We tried to coadminister 2 mg PER (0.09 mg/kg) with PB (120 mg/day @ 5.2 mg/kg/day), LTG (100 mg/day @ 4.3 mg/kg/day), CLB (20 mg/day @ 0.87 mg/kg/day) and VPA (600 mg/day @ 26.1 mg/kg/day) when the patient was 13 years of age (Fig. 2).
EEG performed while awake at 13 years of age.. The EEG showed bilaterally independent occipital spikes.
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The patient's EEG on day 35 showed only bilateral occipital focal spikes (Fig. 3).