PMC10076740_01
Brain MRI and fundoscopic findings at the time of visual disturbance onset. (A) Axial T2-weighted image showed diffuse swelling of both optic nerves (arrow); (B) Optic disc edema (arrow) and macular star (arrowhead).
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Fundoscopy revealed bilateral optic disc edema with a macular star, and brain MRI revealed diffuse swelling of both optic nerves without clear leptomeningeal and parenchymal abnormalities ( Figure 1 ).
Schedule of triple intrathecal chemotherapy after CNS blast crisis and serial results of CSF WBC count. CNS, central nerve system; CSF, cerebrospinal fluid; WBC, white blood cell.
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Hence, she was administered an additional five doses of ITT chemotherapy and a subsequent allogeneic HSCT was planned ( Figure 2 ).