PMC6462390_01
PMC6462390_02
Cerebral axial T2-weighted magnetic resonance imaging showing a well circumscribed multi-lobulated extra-axial mass in the right cerebellopontine angle with cerebellar compression
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The cranial nerve complexes VII and VIII could not be differentiated from the mass and the radiological diagnosis at that time was acoustic neurinoma (Figure 1).
Microscopic appearance of the tumour showing papillary structures lined by a single layer of cuboidal epithelium (Hematoxylin and Eosin x 250)
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The neoplastic cells showed monomorphic nuclei with no mitotic figures, atypia or necrosis seen (Figure 2).
Immunostaining feature: positivity of tumoral cells for epithelial membrane antigen (EMA) (x 250)
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Immunohistochemical study was performed and the tumour showed positivity towards cytokeratin, epithelial membrane antigen (EMA), vimentin and focal positivity towards glial fibrillary acidic protein (GFAP) (Figure 3).