PMC6325367_01
Brain MRI scans of the patient. A-F: DWI performed 10 days after glyphosate intoxication shows hyperintense signals in the bilateral hippocampi (arrows, A). ADC map demonstrates slightly hyperintense signal in the adjacent brain tissues (B). T2WI images (arrows, C and D) and FLAIR images (arrows, E and F) show hyperintense signals in the bilateral hippocampi and fornices. G-I: Imaging performed 14 months after the initial MRI. T2WI images (arrows, G) and FLAIR images (arrows, H and I) show normalized signal intensities in the bilateral hippocampi and fornices. ADC: apparent diffusion coefficient, DWI: diffusion-weighted imaging, T2WI: T2-weighted imaging.
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F1
T2-"shine-through" effect (Fig. 1A and B). T2-weighted imaging (T2WI) (Fig. 1C and D) and FLAIR imaging (Fig. 1E and F) revealed hyperintense lesions in the bilateral hippocampi and fornices with mild swelling. FLAIR imaging (Fig. 1H and I) performed 14 months later showed isosignal intensities in the bilateral hippocampi and fornices. Follow-up neuropsychological tests performed about 3 years later showed significant improvements in both memory and executive function, with him scoring 28/30 on the MMSE, missing one word on recall (2/3).