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(a-c) CT images showing part-solid opacities with central solid component surrounded by a ground-glass opacity halo. (d) Sub-solid non-round ground-glass opacity. (e) Example of two ill-defined pure ground glass opacities.
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CT demonstrated multiple pulmonary sub-solid opacities, many of which were part-solid with a central solid component and a ground-glass halo, others were small pure ground glass nodules (Figure 1).
H&E preparation, 200x magnification with image of IgG4 immunohistochemistry (inset). Interstitial fibrosis with lymphoplasmacytic chronic inflammatory infiltrate containing many IgG4 positive plasma cells.
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Immunohistochemistry confirmed the lymphoplasmacytic nature of the infiltrate with many of the plasma cells expressing IgG4 (more than 50 per high power field) (Figure 2).