PMC4461764_01
Scrotal ultrasonography of AT: scrotal ultrasound scan revealing a 10 x 8 mm, hyperechoic solid mass in the upper pole of the left testicle.
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State, USA) revealed 8 mm x 10 mm, hypoechoic homogeneous solid mass with unclear margin at the junction of the epididymis and left testis (Figure 1). Serum tumor markers, including alpha-fetoprotein, beta-human chorionic gonadotropin, and lactate dehydrogenase, were all within normal limits.
HE staining of AT: (a) hematoxylin-eosin stain of tumor biopsy showing tumor cells lined in irregular, glandular pattern, and fibrous tissue proliferation in stroma with unclear margins (x100); (b) the neoplastic cells had round to polygonal outlines, moderate to abundant pale to vacuolated cytoplasm with round or oval nuclei. No mitoses were seen (hematoxylin-eosin, x200).
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Final histological examination confirmed the diagnosis of AT from the tunica albuginea (Figure 2).
Immunostaining of adenomatoid tumors. (a) Calretinin (+); (b) cytokeratin (+); (c) vimentin (+) (x200).
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Immunohistochemical analysis revealed the tumor cells were positive for calretinin, cytokeratin, and vimentin (Figure 3).