PMC8101682_01
Gross view of the swelling in the right lower eyelid (arrow) along with a fleshy growth in the conjunctiva (arrowhead) of the same eye encroaching upon the cornea.
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Photomicrograph of the eyelid lesion demonstrates glandular spaces lined by tall cells exhibiting uniform round to oval nuclei, fine chromatin, and abundant granular eosinophilic cytoplasm (oncocytes). At places, there was evidence of secretion within the glandular spaces and interspersed lymphoplasmacytic inflammation (H&E, A - 4X; B - 10X; C - 10X; D - 40X).
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The microscopic features were consistent with a diagnosis of oncocytoma (Figure 2).
Histopathology of the conjunctival lesion exhibits a superficial biopsy comprising only acanthotic stratified squamous epithelium displaying severe dysplasia (H&E, A - 10X; B - 40X).
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Adjuvant topical chemotherapy with 5-fluorouracil was prescribed to the patient to minimize recurrence (Figure 3).