PMC8605421_01
Chest X-ray (A) and computed tomography (B) showed a large mass with lymph nodes in the right hilar region and pleural effusion. Histological findings of the transbronchial biopsy of the tumor showing small-cell lung cancer. H&E x400 (C), CD56x400 (D), chromogranin A x400 (E), synaptophysin x100 (F). H&E, Hematoxylin and eosin.
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Significant facial edema was observed, and chest computed tomography (CT) showed superior vena cava (SVC) syndrome (Fig. 1A,B). A transbronchial biopsy was performed 3 days before chemotherapy and confirmed the diagnosis of SCLC histologically (Fig. 1C-F).
Abdominal computed tomography on the 24th day showed intestinal dilatation and ileocecal stacking (A) and 36 mm x 30 mm liver abscess in the left of the liver (B, a white arrow).
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Macroscopic pathology of the resected colon showed multiple ulcerative lesions (A). Histological findings of the surgically resected colon showing inflammatory infiltrate Entamoeba histolytica trophozoites and erythrophagocytosis (B, H&E x400). H&E x40 (C), PAS x40 (D), H&E x100 (E), PAS x100 (F). H&E, Hematoxylin and eosin; PAS, Periodic acid-schiff.
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Pathological specimens revealed Entamoeba histolytica trophozoites on the colon, severe inflammatory cell infiltration of the entire layer of the intestinal wall, abscess formation accompanied by bleeding and fibrin in some parts, and loss of continuity of the intestinal wall (Fig. 3).
Summary of clinical course. WBC, white blood cell; CRP, C-reactive protein; SBT/ABPC, Sulbactam and ampicillin; MEPM, meropenem; TAZ/PIPC, tazobactam and piperacillin; VCM, vancomycin; MCFG, micafungin; MNZ, metronidazole; PRM, paromomycin.
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Therefore, we concluded that the amoebic dysentery was cured (Fig. 4).