PMC6147932_01
Part of thyroid follicle lined by columnar cells with pleomorphic grooved nuclei (H & E x 400).
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Histopathologically, this nodule showed crowded, colloid-filled thyroid follicles lined by columnar-cuboidal cells with an eosinophilic cytoplasm and crowded, pleomorphic, large, pale nuclei with focal areas of nuclear grooving and prominence of nucleoli (Figure 1).
Thyroglobulin positive follicle cells in papillary carcinoma (Thyroglobulin x 200).
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These cells stained positively with a thyroglobulin tumour marker (Figure 2).
Congo red-positive staining of amyloid in the stroma (x 200).
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These cells had round nuclei and a pale-eosinophilic cytoplasm (Figure 3).
Calcitonin positive tumours cells in the medullary carcinoma (calcitonin x 400).
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Tumor cells stained strongly positive with calcitonin (Figure 4).