PMC3027001_01
Low-power examination revealed abnormal keratin, severe dermal sun damage, tattoo pigment, and a cellular dermal neoplasm.
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fig1
Microscopically, a poorly differentiated carcinoma was present within a sun-damaged dermis, infiltrating amongst dermal tattoo pigment as single cells and nests (Figures 1-4).
Basal keratinocyte dysplasia showing abnormal downward growth, abnormal surface keratin, and tattoo pigment within papillary dermis was noted.
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fig2
Microscopically, a poorly differentiated carcinoma was present within a sun-damaged dermis, infiltrating amongst dermal tattoo pigment as single cells and nests (Figures 1-4). The overlying epidermis showed focal abnormal keratin and basal keratinocyte dysplasia (Figure 2). 
High-power photomicrograph demonstrates cells with enlarged nuclei, one-to-two prominent nucleoli, cytoplasmic keratin, well-defined cell borders, and early pearl formation, features indicative of squamous differentiation.
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fig3
Microscopically, a poorly differentiated carcinoma was present within a sun-damaged dermis, infiltrating amongst dermal tattoo pigment as single cells and nests (Figures 1-4). Cytologically, the malignant cells displayed enlarged nuclei, one to two prominent nucleoli, abnormal cytoplasmic keratin, and intercellular bridges (desmosomes), typical of squamous differentiation (Figure 3).
Epithelioid and spindled squamous cells are seen infiltrating amongst dermal tattoo pigment.
CRIM2010-431813.004.jpg
PMC3027001_01_CRIM2010-431813.004.jpg
fig4
Microscopically, a poorly differentiated carcinoma was present within a sun-damaged dermis, infiltrating amongst dermal tattoo pigment as single cells and nests (Figures 1-4).