PMC5869558_01
General view of the vulvar schwannoma before surgical resection: a round subcutaneous nontender solitary tumor with a blue-gray color and a black dot on the left labium majus.
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F1
The overlying skin was smooth with a blue-gray color, and a black dot was noticed in the middle (Fig. 1).
Histopathological examination showed a palisade pattern and a swirling pattern, forming Verocay bodies. a HE stain, x40. b HE stain, x200. Red arrow, Antoni A area; yellow arrow, Antoni B area; black arrow, Verocay bodies.
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F2
Histopathological examination with HE staining showed a typical schwannoma (Fig. 2).
Immunohistochemical examination showed that the spindle cells were diffusely positive for S-100 protein.
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F3
Immunohistochemistry showed that interweaving bundles of spindle cells were strongly positive for S-100 protein (Fig. 3) and negative for CD34 and NF, which confirmed the diagnosis of benign schwannoma.