PMC10401826_01
(A) Change trends in the levels of the IIRPCs, CEA, and CA15-3 during follow-up of case 1. The left vertical coordinate applied to the values of IIRPCs, the right vertical coordinate applied to the values of CEA (ng/ml) and CA15-3 (U/ml). (B) Change trends in the levels of the IIRPCs, CEA, and CA15-3 during follow-up of case 2. The left vertical coordinate applied to the values of IIRPCs and CA15-3 (U/ml), the right vertical coordinate applied to the values of CEA (ng/ml). (C) Examples of serum IIRPCs with or without tumor metastasis. The amount of serum IIRPCs relative to serum TRPC in each gel was quantified. The gray value of IIRPCs in metastasis patients (A and B) is substantially higher than in disease-free patients (C and D).
fonc-13-1207991-g001.jpg
PMC10401826_02_fonc-13-1207991-g001.jpg
f1
The detection method for IIRPCs and the quantification method were the same as in case 1.  Figure 1B  demonstrated the dynamic changes of IIRPCs as well as tumor markers of this patient. IIRPCs did not decrease to the baseline(the level at the first sampling, shown in  Figure 1B ). In this case, her CEA and CA15-3 levels also increased significantly with disease progression.
PMC10401826_02
(A) Change trends in the levels of the IIRPCs, CEA, and CA15-3 during follow-up of case 1. The left vertical coordinate applied to the values of IIRPCs, the right vertical coordinate applied to the values of CEA (ng/ml) and CA15-3 (U/ml). (B) Change trends in the levels of the IIRPCs, CEA, and CA15-3 during follow-up of case 2. The left vertical coordinate applied to the values of IIRPCs and CA15-3 (U/ml), the right vertical coordinate applied to the values of CEA (ng/ml). (C) Examples of serum IIRPCs with or without tumor metastasis. The amount of serum IIRPCs relative to serum TRPC in each gel was quantified. The gray value of IIRPCs in metastasis patients (A and B) is substantially higher than in disease-free patients (C and D).
fonc-13-1207991-g001.jpg
PMC10401826_02_fonc-13-1207991-g001.jpg
f1
The detection method for IIRPCs and the quantification method were the same as in case 1.  Figure 1B  demonstrated the dynamic changes of IIRPCs as well as tumor markers of this patient. IIRPCs did not decrease to the baseline(the level at the first sampling, shown in  Figure 1B ). In this case, her CEA and CA15-3 levels also increased significantly with disease progression.