PMC9303153_01
At baseline, the color fundus photograph (CFP) of the left eye (OS) showed the presence of angioid streaks (AS) with subretinal hemorrhage (SRH) suggestive of an underlying choroidal neovascularization (CNV) (a). Spectral-domain optical coherence tomography of the OS illustrated the presence of subretinal fluid (SRF) with subretinal hyperreflectivity and thickened Bruch's membrane (b). After undergoing intravitreal brolucizumab injection, the SRH reduced significantly at one month (c) and disappeared completely by three months (e) as noted on the CFP. The SD-OCT scans at months 1 (d) and 3 (f) demonstrated complete resolution of the fluid and a reduction in the subretinal hyperreflectivity.
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fig1
There were no ocular or systemic adverse effects observed.  Figure 1 depicts the changes in color fundus photograph (CFP) and SD-OCT in OU throughout the course of the treatment.