PMC3959423_01
Upper endoscopy showing rings in the middle third of the esophagus (white arrow). Black arrow shows mucosal split at the lower end during endoscopy
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F1
A later endoscopy showed a tight distal stricture and course rings at the middle third of the esophagus (Fig. 1). A mucosal split occurred during endoscopy (Fig. 1, black arrow).
HE stains showing infiltration of large number of intraepithelial lymphocytes in the peripapillary area without or rare granulocytes
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F2
Biopsies taken from the middle third of the esophagus showed marked infiltration of exclusive intraepithelial lymphocytes in a peripapillary distribution (Fig. 2).
Immunostains showing presence of CD3 cells (T cells)
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F3
The immunostains showed presence of CD3 and CD5 lymphocytes (T cell markers) in the epithelium (Fig. 3).