PMC6220404_01
CT image showed right renal mass (arrow).
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CT revealed a mass measured in 9.7x7.0 cm in the lower portion of the right kidney (Figure 1). CT also revealed multiple small nodules in lower lobes of lungs, suspecting metastatic tumors (Figure 2).
CT image showed right lung mass suspected for metastasis (arrow).
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CT revealed a mass measured in 9.7x7.0 cm in the lower portion of the right kidney (Figure 1). CT also revealed multiple small nodules in lower lobes of lungs, suspecting metastatic tumors (Figure 2).
Gross findings of the tumor. 55x94 mm white to tan tumor occupied the lower portion of the right kidney. Marked hemorrhage was found (a, b).
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Grossly, 55x94 mm white to tan tumor occupied the lower portion of the right kidney (Figure 3).
Microscopic findings of the tumor. (a) Tumor cells grow in a solid sheet. (b) Hemorrhage was marked. (c) Tumor cells have relatively bland nuclei and clear to eosinophilic cytoplasm. Cell border is indistinct. (d) Mitosis is observed (hematoxylin & eosin staining, (a, b): x5, (c): x20, (d): x40).
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Microscopically, polygonal to ovoid tumor cells with round nuclei and clear to eosinophilic cytoplasm made solid tumor (Figure 4). Mitosis was found in 5/10 high power field (Figure 4).
Immunohistochemical analysis. Tumor cells are positive for (a) CD34, (b) SMA, and (c) Renin. (d) MIB1 labeling index was 4% ((a, b, d): x10, (c): x20).
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CD34 were positive (Figure 5). Cytokeratin (AE1/AE3), cytokeratin (CAM5.2), EMA, PAX8, S-100, HMB45, c-kit, and STAT6 were negative. MIB1 labeling index was 4% (Figure 5).
Ultrastructurally, near rhomboid crystalline structures were observed.
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Ultrastructurally, near rhomboid crystalline structure was observed (Figure 6).