PMC6323427_01
Computed tomographic coronal section showing hepatosplenomegaly.
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It showed hepatosplenomegaly but no intra-abdominal abscesses (Figure 1).
Marked anisopoikilocytosis with microcytosis. Teardrop cells, target cells, and contracted red blood cells can be seen. Leukopenia and thrombocytopenia are present.
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Peripheral blood film showed marked leukopenia, thrombocytopenia, and significant anisopoikilocytosis with microcytosis and target and tear drop cells consistent with a picture of thalassaemia intermedia (Figure 2).
Hypocellular marrow fragment for age with decreased cell trails.
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A's marrow however was hypocellular with decreased cell trails on the aspirate (Figure 3).
(a, b) Giant erythroblasts with inclusion bodies dwarfing the granulocyte precursors.
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There was marked erythroid hypoplasia with rare giant erythroblasts, and inclusion bodies were seen (Figure 4).
Haemosiderin-laden macrophage with active haemophagocytosis of an RBC.
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There were also increased numbers of macrophages with active haemophagocytosis (Figure 5).