PMC8214721_01
A Timeline of cardiac biomarker levels in response to interventions throughout hospital stay. Interventions at 1 are as follows: start broad-spectrum antibiotics cefuroxime and metronidazole, start prednisolone 60 mg once daily, and high doses of prophylactic nadroparin 0.6 mL daily. Interventions at 2 are as follows: addition gentamicin to cefuroxime and metronidazole; start IVIG 150 g once (and next day 80 g once) for a total of 2 days of treatment; start high doses of acetylsalicylacid 600 mg four times daily during 2 days, followed by 200 mg once daily; prednisolone 80 mg twice daily during a day, followed by 80 mg once daily during 5 days; and start high-flow nasal oxygen therapy and diuretics. B Timeline of the inflammatory marker levels in response to the described interventions above
42399_2021_998_Fig1_HTML.jpg
PMC8214721_01_42399_2021_998_Fig1_HTML.jpg
Fig1
Table 1 and Fig. 1). The contrast enhanced computed tomographic scan (CT) of the thorax and abdomen revealed splenomegaly and thickening of the terminal ileum in a long traject of at least 20 cm. Table 1 and Fig. 1).
Images of echocardiogram at hospitalization day 2; suspicion on cardiac involvement as part of MIS. The panels below demonstrate depressed systolic left ventricular function, slight tricuspidal valve insufficiency, aotic valve with 3 leaflets without pericardial effusion, and a dilated vena cava inferior
42399_2021_998_Fig2_HTML.jpg
PMC8214721_01_42399_2021_998_Fig2_HTML.jpg
Fig2
The echocardiogram revealed a moderately reduced systolic left ventricular function with estimated ejection fraction of below 40%, with global hypokinesia without regional wall motion abnormalities related to a circulation area of a specific coronary artery (see Fig. 2).