PMC3905163_01
Histologic specimen of carcinoma ex pleomorphic adenoma of the parotid. Image shows the poorly differentiated malignant epithelial component in pleomorphic adenoma (A). Immunohistochemical staining demonstrated strong and diffuse positivity for a cocktail of cytokeratins (B).
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F1
Moreover, Ki67 labeling index was 50% (Figure 1).
18F-FDG PET images of splenic metastasis. Axial section (A) and coronal section (B).
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F2
Indeed, a PET scan confirmed the presence of two hypercaptant lesions in the left lung (SUV 4.1) and in the spleen (SUV 10.6) (Figure 2).
CT images of splenic metastasis. Axial section (A) and coronal section (B).
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F3
In April of 2013, the patient underwent a new CT scan showing a low-density nodular lesion measuring 1.7 cm in the apical segment of the upper lobe of the left lung that had increased in volume and a hypovascular lesion measuring 4.8 cm in the superior-medial portion of the spleen, which had also increased in volume (Figure 3).
Histologic specimen of splenic metastasis. The spleen is involved by atypical epitheliomorphic cells, arranged in solid nests and cords with a round or oval nucleus and a large eosinophilic cytoplasm (A); immunohistochemical staining demonstrated positivity for cytokeratin 7 (B).
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F4