PMC5831945_01
MRI showing right solid extra-axial parieto-occipital lesion with typical characteristics of meningeal myelomatosis. The tumor adapts to the underlying brain surface, is intensely enhanced with contrast, and shows adjacent pachymeningeal enhancement with focal spread through leptomeninges towards sulci in the proximal convexity, associated with vasogenic edema but not causing intracranial herniation.
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fig1
The tumor adapted to the underlying brain surface showing adjacent pachymeningeal enhancement with focal spread through leptomeninges (Figure 1).
Pathological study: tumor proliferation of diffuse growth plasma cells made up of atypical plasma cells. The tumor immunophenotype shows lambda light chain restriction. The rest of the markers analyzed were negative (EMA, CD56, CD117, CD20, CD79a, and CD3). The Ki-67 proliferative index was approximately 30-40%.
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fig2
A biopsy of the cranial lesion was conducted on November 12, 2015, with pathological diagnosis of plasmacytoma (Figure 2).