PMC4531763_01
Chest PA shows well-marginated huge left suprahilar mass shadow.
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Chest X-ray (Figure 1) and chest CT scan (Figure 2) revealed a 12x10 cm-sized well-defined and partially capsulated and lobulated homogeneous attenuated mass in the anterior mediastinum.
Chest CT shows 12x10cm-sized well-defined, partially capsulated and lobulated homogenous attenuated mass in the anterior mediastinum.
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Chest X-ray (Figure 1) and chest CT scan (Figure 2) revealed a 12x10 cm-sized well-defined and partially capsulated and lobulated homogeneous attenuated mass in the anterior mediastinum.
The light microscopic section shows a predominantly diffuse pattern of monotonous neoplastic cells arranged in organoid cell nests (classic "Zellballen" pattern) that are characteristics of paraganglioma.
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Light microscopic sections showed a predominantly diffuse pattern of monotonous neoplastic cells arranged in organoid cell nests (classic "Zellballen" pattern) that are characteristics of paraganglioma (Figure 3).
Immunohistochemical stain reveals a positive for S-100 protein in scattered supporting cells.
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Immunoreactivity for S-100 protein, confirming the presence of sustentacular cells which are characteristics of paraganglioma, was detected in scattered supporting cells, mostly at the periphery of the tumor cell nests(Figure 4).