PMC7670738_01
PMC7670738_02
Frequency of blood transfusions of study subjects according to their hematological disease. ITP: idiopathic thrombocytopenic purpura; SCD: sickle cell disease.
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He was among the patient group with the highest blood transfusion rates in the past 12 months (Figure 1).
Phylogenetic tree showing the genetic similarity between the 5' LTR region aligned sequence (611pb) of the HTLV-2 strain isolated in this study, and the sequences of 48 strains from the Genbank database. The tree was constructed using the neighbor-joining method and a bootstrap of 1,000 replicates. The branch of the isolated sample (JLM151) is labeled by a red dot.
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The JLM151 sample (GenBank accession number MN 266910) was clustered within the subtype HTLV-2c, the same clade of the samples isolated from the Kayapo tribe (AF306731 and AF306731) (Figure 2).The distribution of HTLV-2 subtypes suggests that the viruses were gradually and distinctly dispersed around the world through different migratory events starting from the Africa continent.