PMC8717002_01
Computed Tomography of the abdomen and pelvis - coronal view. Black arrow pointing to moderate right hydroureteronephrosis. Red arrow pointing to calcium containing lesion measuring 1.9 x 2.1 cm
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Computed Tomography (CT) of the abdomen and pelvis revealed an ill-defined, hypodense calcium containing lesion measuring 1.9 x 2.1 cm distal to the right iliac bifurcation causing moderate right hydroureteronephrosis (Figure 1).
Angiomyomatous hamartoma measuring 10 x 5 x 5 cm, excised from right groin
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The surgeons also excised the right groin cystic mass and sent it for pathology which later resulted as a benign angiomyomatous hamartoma (Figure 2).
Immunohistochemistry stains show EHE tumor cells are positive for: A. vascular marker Erythroblast transformation-specific-related gene (anti-ERG antibody, x100); B. tumor specific marker Calmodulin-binding transcription activator 1 (anti-CAMTA1 antibody, x100); C. non-specific marker Cluster of differentiation 56 (anti-CD56 antibody, x100); D. vascular marker Cluster of differentiation 31 (anti-CD31 antibody, x100); E. Friend leukemia integration 1 transcription factor (anti-FLI1 antibody, x100). F. cords and single cells of large endothelial cells with abundant eosinophilic cytoplasm embedded in a myxohyaline stroma (HE, x200).
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By this time, the patient's retroperitoneal biopsy results returned from Mayo clinic as an epithelioid hemangioendothelioma that was positive for the markers: cluster of differentiation 31 (CD31), erythroblast transformation-specific-related gene (ERG), friend leukemia integration 1 transcription factor (FLI1), calmodulin-binding transcription activator 1 (CAMTA1), and cluster of differentiation 56 (CD56) (Figure 3).