PMC5498206_01
Chest computed tomography images of the patients at admission, before the first administration of rituximab (RTX), and after the series of RTX treatments.
1349-7235-56-1399-g001.jpg
PMC5498206_03_1349-7235-56-1399-g001.jpg
g001
CK level of 399 U/L and a ferritin level of 853 ng/mL. Chest CT showed interstitial shadows (Fig. 1). On the 5th day, the chest CT findings suggested that her condition had deteriorated (Fig. 1); we therefore administered RTX [500 mg (375 mg/m2)] on the 7th day, followed by mPSL (1 g for 3 days) from the 8th day.
CyA: cyclosporine A, IVCY: intravenous cyclophosphamide, mPSL: methylprednisolone, MMF: mycophenolate mofetil, RTX: rituximab, Tac: tacrolimus
1349-7235-56-1399-g002.jpg
PMC5498206_01_1349-7235-56-1399-g002.jpg
g002
She was anti-MDA5 antibody-positive (Fig. 2).
PMC5498206_02
Chest computed tomography images of the patients at admission, before the first administration of rituximab (RTX), and after the series of RTX treatments.
1349-7235-56-1399-g001.jpg
PMC5498206_03_1349-7235-56-1399-g001.jpg
g001
CK level of 399 U/L and a ferritin level of 853 ng/mL. Chest CT showed interstitial shadows (Fig. 1). On the 5th day, the chest CT findings suggested that her condition had deteriorated (Fig. 1); we therefore administered RTX [500 mg (375 mg/m2)] on the 7th day, followed by mPSL (1 g for 3 days) from the 8th day.
CyA: cyclosporine A, IVCY: intravenous cyclophosphamide, mPSL: methylprednisolone, RTX: rituximab, Tac: tacrolimus, TCZ: tocilizumab
1349-7235-56-1399-g003.jpg
PMC5498206_02_1349-7235-56-1399-g003.jpg
g003
However, the patient did not respond and died on the 18th day after re-admission to hospital (Fig. 3).
PMC5498206_03
Chest computed tomography images of the patients at admission, before the first administration of rituximab (RTX), and after the series of RTX treatments.
1349-7235-56-1399-g001.jpg
PMC5498206_03_1349-7235-56-1399-g001.jpg
g001
CK level of 399 U/L and a ferritin level of 853 ng/mL. Chest CT showed interstitial shadows (Fig. 1). On the 5th day, the chest CT findings suggested that her condition had deteriorated (Fig. 1); we therefore administered RTX [500 mg (375 mg/m2)] on the 7th day, followed by mPSL (1 g for 3 days) from the 8th day.