PMC6452533_01
(a) H&E stain showing extensive acute tubular necrosis with associated peritubular capillaritis and interstitial nephritis; (b) H&E stain showing polarizable oxalate crystals in a tubule; (c) H&E stain showing active endothelialitis in one large caliber artery, (d) electron microscopy showing electron-dense deposits with immunoreactivity for IgA, in keeping with a remote IgA-dominant immune complex mediated nephropathy in the donor.
CRIT2019-8942062.001.jpg
PMC6452533_01_CRIT2019-8942062.001.jpg
fig1
This showed extensive acute tubular necrosis with associated peritubular capillaritis and interstitial nephritis (Figure 1).
(a) H+E stain revealing residual acute tubular injury with focal epithelial necrosis and associated mild peritubular capillaritis and interstitial nephritis; (b) H+E stain showing polarizable oxalate crystals in several tubules; (c) H&E stain revealing acute tubular necrosis and oxalate crystals in the tubules; (d) PAS stain showing dilated peritubular capillaries with capillaritis and active interstitial nephritis.
CRIT2019-8942062.002.jpg
PMC6452533_01_CRIT2019-8942062.002.jpg
fig2
This revealed residual acute tubular necrosis with associated mild peritubular capillaritis and interstitial nephritis (Figure 2).