PMC8352853_01
CT of the neck demonstrating left multiples supraclavicular lymphadenopathy the largest measured 10 x 11 mm (arrowed).
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PCR was negative. Computed tomographic scan for chest and neck revealed multiple left cervical and axillary lymph nodes the largest one in the left supraclavicular region measuring around 10 x 11 mm (Fig. 1). Patient was initially treated with ceftriaxone however it was discontinued later on when the results of blood and urine were reported negative.
A low magnification H&E showing partial effacement of the lymph node architecture by pale necrotic foci.
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Sections from the lymph node show effaced lymph node architecture by diffuse polymorphic lymphohistiocytic infiltrate with multiple foci of necrosis (Fig. 2).
CD3 immunohistochemical stain highlights T-cells.
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CD3 (Fig. 3) with no apparent marker expression. CD30 is positive in scattered immunoblasts.
CD20 immunohistochemical stain highlights residual B-cells, while T-cells are negative for CD20.
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The residual of B lymphocytes are positive for CD20 (Fig. 4) and other B-cell markers with no apparent marker expression.