PMC5397646_01
20x micrographs, (a-d). Spindle cell neoplasm (a) is more cellular when compared to surrounding liver tissue (b). The tumor cells of spindle cell neoplasm (a) appear uniform, with monomorphic nuclei and eosinophilic cytoplasm. Tumor cells stain strongly positive for CD117 (c) and DOG1 (d).
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fig1
Immunohistochemical stains showed that tumor cells are positive for CD117 and DOG1 and negative for pancytokeratin, hepatocytic specific antigen, S-100, and SMA, supporting the above diagnosis (Figure 1).