PMC5080467_01
Noncirrhotic liver parenchyma but with significant portal hypertension including splenomegaly and varices.
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fig1
Triple-phase CT scan (Figure 1) demonstrated a noncirrhotic liver parenchyma but with evidence of significant portal hypertension including splenomegaly and varices.
Hepatic adenoma. Well-differentiated neoplasm composed of normal appearing hepatocytes arranged in sheets and thin cords with patchy pseudoacinar growth pattern (thin arrows), scattered inflammatory foci, and bands of fibrosis with unpaired arteries (thick arrow) (H&E, 200x).
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fig2
Immunohistochemistry demonstrated diffuse glutamine synthetase and CRP staining and patchy SAA staining which favored the diagnosis of hepatocellular adenoma, inflammatory subtype (Figure 2).
Dense portal fibrosis with loss of portal veins branches (H&E and trichrome stain, 100x).
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fig3
HPS (Figure 3). Hepatic venous pressure gradient was 2 mmHg.