PMC4763636_01
Biopsy demonstrating dermal and follicular infiltrate (H and E, x10) (a) with epidermotropism and Pautrier microabscess (H and E, x40) (b) and mycosis fungoides cells with cerebriform nuclei (H and E, x100) (c)
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F1
A 61-year-old female presented with a 35 years history of refractory Stage IB MF [Figures 1 and 2].
Images of patient's mycosis fungoides on the left groin (a and b) and natal cleft (c)
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F2
A 61-year-old female presented with a 35 years history of refractory Stage IB MF [Figures 1 and 2].
Images of patient's mycosis fungoides after 3 weeks of topical imiquimod treatment showing left groin (a) and natal cleft (b)
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F3
A dramatic improvement was noted [Figure 3], the patient treated plaques on average for only 3 weeks to achieve prolonged (6 months) clearance, although treatment caused significant lethargy, aching, and flu-like symptoms.
PMC4763636_02
PMC4763636_03