PMC3236712_01
Case 1: (A, B, C, and D) Optomap color fundus imaging (A and B) and wide-field FAF (C and D) of the right (A and C) and left eye (B and D). (E and F) corresponding visual fields measured with Goldmann manual perimetry. The nasal paracentral scotoma of the right eye, and the large scotoma extending from the blind spot nasally on the left eye correspond well with the areas of reduced FAF.. Abbreviation: FAF, fundus autofluorescence.
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Fundus examination of both eyes showed cream-colored and depigmented spots (Figure 1A and B). Areas of reduced FAF corresponded to the visual field defects (Figure 1C-F).
PMC3236712_02
Case 2: (A and B) Optomap color fundus imaging (A) and wide-field FAF (B) of the right eye. (C) Corresponding visual field measured with Goldmann manual perimetry.. Abbreviation: FAF, fundus autofluorescence.
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The left eye showed multiple, deep creamy-yellow choroidal lesions at the posterior pole and an old paracentral scar (Figure 2A). Corresponding to the visual field (scotoma left eye: temporal 20 , nasal 15 , superior 15 , inferior 0 ), a loss of FAF was seen extending from the papilla below and temporal to the macula (Figure 2B and C).
PMC3236712_03
Case 3: (A, B, C, and D) Optomap color imaging (A and B), wide-field FAF (C and D) of the right and left eye, and corresponding visual fields (E and F). In both eyes peripapillary arc-shaped areas of hypofluorescence extending from the central pole, surrounded by hyperfluorescent borders can be seen in Optomap FAF (C and D).. Abbreviation: FAF, fundus autofluorescence.
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FAF revealed peripapillary arc-shaped areas of hypofluorescence extending from the central pole, surrounded by hyperfluorescent borders (Figure 3C and D). Findings from FAF, especially regarding the hypofluorescence areas, showed correspondence to relative scotoma in visual field obtained by Goldmann perimetry (scotoma right eye: temporal 20 , nasal 20 , superior 20 , inferior 0 , left eye: temporal 20 , nasal 25 , superior 20 , inferior 20 ) (Figure 3).
PMC3236712_04
Case 4: (A, B, C, and D) Optomap color imaging (A and B), wide-field FAF (C and D) of the right eye and left, and corresponding visual fields (E and F). In both eyes, pigmented scars at the posterior pole and the periphery can be seen in Optomap color fundus imaging. FAF reveals distinct serpiginous and geographic areas of reduced FAF in both eyes. These findings correspond to visual field defects found in Goldmann perimetry.. Abbreviation: FAF, fundus autofluorescence.
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Fundus examination on both eyes showed pigmented scars in the area of the posterior pole and pigmented scars in the periphery with no signs of active inflammation (Figure 4A and B). The autofluorescence images showed a distinctive geographic configuration that originated peripapillary and in the macular area and extended centrifugally (Figure 4C and D). The areas of RPE atrophy corresponded to the visual field as measured by Goldmann perimetry, presenting a central scotoma and decreased peripheral field of vision (Figure 4C-F).