PMC3253409_01
Imaging findings and histopathology of pancreatic amyloidosis.. A. Ultrasonography shows diffuse hypoechoic, enlarged pancreas including multiple millimetric calcifications with posterior acoustic enhancement (arrow). There is no pancreatic duct dilatation. B. Axial CT image shows diffuse prominent enlargement of pancreas (arrow), with multiple hyperdense calcifications (thin arrow). C. Axial CT after contrast enhancement on venous phase shows diffuse contrast enhancement of pancreas parenchyma with absence of inflammatory changes in peripancreratic tissues. D. Normal high signal intensity of pancreas is decreased on axial T1-weighted image. Pancreas is seen diffusely hypointense (arrow). E. Axial T2-weighted image of abdomen shows diffusely enlarged pancreas (arrow), with hyperintense cystic components (thin arrow). Pancreas tail is seen more hyperintense than body with no inflammation. Also, pancreatic duct is not dilated. F. Histopathologic examination reveals amyloid deposition stained with congo red islet cells of Langerhans (arrows).
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F1
Ultrasonography (US) of the patient showed a diffusely enlarged hypoechoic pancreas with punctate hyperechogenities representing calcifications (Fig. 1A). T1- and T2-weighted images (Fig. 1D, E). There were hyperintense cystic nodules in pancreas parenchyma on T2-weighted images (Fig. 1E). Exocrine cells of the pancreas were spared (Fig. 1F).