PMC7171645_01
Clinical illustrations. (a) 7th postoperative day. (b) 15 hours after switch. (c) 11th postoperative day.
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On the seventh day after surgery, all LMWH injection sites became increasingly painful and inflamed and showed necrotic central lesions and blisters, with the first site at the left thigh being the most severely affected (Figure 1). Platelet count increased steadily thereafter, and the local injection sites recovered (Figure 1).
Course of platelet count (150-350 G/L) and aPTT values (27-41 sec).
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On day 6, platelet count decreased to 160 G/l but remained within the normal range (Figure 2).
Antibody levels in our patient.
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On the seventh postoperative day, ELISA tests showed highly positive antibody levels/OD, 2.0 with lysate (HIT), and 0.8 without lysate (PIT) (optical densities from Zymutest  HIA IgG enzyme-linked immunosorbent assay (ELISA) test (Hyphen Biomed)) (Figure 3).