PMC5339517_01
Image of mass in left anterior ethmoid cell extending into left medial aspect of orbit on axial sinus CT without contrast (a), and MRI orbit T1 after contrast (b). Blue arrow indicates area of bony destruction.
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fig1
Angeles after 6 months of left eye tearing. He was seen by an ophthalmologist a month earlier who found left nasolacrimal duct obstruction on exam. A CT orbit revealed a soft tissue mass involving the medial aspect of the left ethmoid and maxillary sinus with osseous destruction (see Figure 1).
Permanent sections showing histology of Rosai-Dorfman disease; low power 100x (a) and high power 400x (b) hematoxylin and eosin stain showing histiocytic infiltrate. Blue arrow indicates emperipolesis. Positive immunostaining for CD68 (c) and S100 (d).
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fig2
The histiocytes were CD68(+), S-100(+), C1Da(-), Desmin(-), and EBV(-) (see Figure 2).