PMC2211476_01
PMC2211476_02
PMC2211476_03
PMC2211476_04
PMC2211476_05
PMC2211476_06
Rapid and sustained improvement in Visuospatial/Executive function following perispinal etanercept documented by the Montreal Cognitive Assessment. The top panel depicts the first three tasks from the Montreal Cognitive Assessment completed by the patient one day prior to perispinal etanercept administration. The middle panel depicts the patient's results two hours after perispinal etanercept administration, showing correct completion of the alternating trail making task documenting improved executive function, and improvement in depiction of a clock face. The bottom panel depicts the patient's results at seven weeks, fourteen days after receiving his previous dose of perispinal etanercept, showing further improvement in his drawing of the clock face, with numerals added, and persistence in improvement in completion of the trail making task. (The instruction for completion of the alternating trail making task are as follows: Please draw a line, going from a number to a letter in ascending order. Begin here [point to (1)] and draw a line from 1 then to A then to 2 and so on. End here [point to (E)]).
1742-2094-5-2-1.jpg
PMC2211476_20_1742-2094-5-2-1.jpg
F1
At seven weeks, fourteen days after receiving his last dose of perispinal etanercept, his Montreal Cognitive Assessment score was 14, with persistent improvement in the trail making task, and improved depiction of the clock face [see Figure 1].
PMC2211476_07
PMC2211476_08
PMC2211476_09
PMC2211476_10
PMC2211476_11
PMC2211476_12
PMC2211476_13
PMC2211476_14
PMC2211476_15
PMC2211476_16
PMC2211476_17
Rapid and sustained improvement in Visuospatial/Executive function following perispinal etanercept documented by the Montreal Cognitive Assessment. The top panel depicts the first three tasks from the Montreal Cognitive Assessment completed by the patient one day prior to perispinal etanercept administration. The middle panel depicts the patient's results two hours after perispinal etanercept administration, showing correct completion of the alternating trail making task documenting improved executive function, and improvement in depiction of a clock face. The bottom panel depicts the patient's results at seven weeks, fourteen days after receiving his previous dose of perispinal etanercept, showing further improvement in his drawing of the clock face, with numerals added, and persistence in improvement in completion of the trail making task. (The instruction for completion of the alternating trail making task are as follows: Please draw a line, going from a number to a letter in ascending order. Begin here [point to (1)] and draw a line from 1 then to A then to 2 and so on. End here [point to (E)]).
1742-2094-5-2-1.jpg
PMC2211476_20_1742-2094-5-2-1.jpg
F1
At seven weeks, fourteen days after receiving his last dose of perispinal etanercept, his Montreal Cognitive Assessment score was 14, with persistent improvement in the trail making task, and improved depiction of the clock face [see Figure 1].
PMC2211476_18
PMC2211476_19
Rapid and sustained improvement in Visuospatial/Executive function following perispinal etanercept documented by the Montreal Cognitive Assessment. The top panel depicts the first three tasks from the Montreal Cognitive Assessment completed by the patient one day prior to perispinal etanercept administration. The middle panel depicts the patient's results two hours after perispinal etanercept administration, showing correct completion of the alternating trail making task documenting improved executive function, and improvement in depiction of a clock face. The bottom panel depicts the patient's results at seven weeks, fourteen days after receiving his previous dose of perispinal etanercept, showing further improvement in his drawing of the clock face, with numerals added, and persistence in improvement in completion of the trail making task. (The instruction for completion of the alternating trail making task are as follows: Please draw a line, going from a number to a letter in ascending order. Begin here [point to (1)] and draw a line from 1 then to A then to 2 and so on. End here [point to (E)]).
1742-2094-5-2-1.jpg
PMC2211476_20_1742-2094-5-2-1.jpg
F1
At seven weeks, fourteen days after receiving his last dose of perispinal etanercept, his Montreal Cognitive Assessment score was 14, with persistent improvement in the trail making task, and improved depiction of the clock face [see Figure 1].
PMC2211476_20
Rapid and sustained improvement in Visuospatial/Executive function following perispinal etanercept documented by the Montreal Cognitive Assessment. The top panel depicts the first three tasks from the Montreal Cognitive Assessment completed by the patient one day prior to perispinal etanercept administration. The middle panel depicts the patient's results two hours after perispinal etanercept administration, showing correct completion of the alternating trail making task documenting improved executive function, and improvement in depiction of a clock face. The bottom panel depicts the patient's results at seven weeks, fourteen days after receiving his previous dose of perispinal etanercept, showing further improvement in his drawing of the clock face, with numerals added, and persistence in improvement in completion of the trail making task. (The instruction for completion of the alternating trail making task are as follows: Please draw a line, going from a number to a letter in ascending order. Begin here [point to (1)] and draw a line from 1 then to A then to 2 and so on. End here [point to (E)]).
1742-2094-5-2-1.jpg
PMC2211476_20_1742-2094-5-2-1.jpg
F1
At seven weeks, fourteen days after receiving his last dose of perispinal etanercept, his Montreal Cognitive Assessment score was 14, with persistent improvement in the trail making task, and improved depiction of the clock face [see Figure 1].