PMC10293599_01
Multiple discrete yellowish-white plaques in the antrum of the stomach on upper GI endoscopy
ijp-18-104-g001.jpg
PMC10293599_01_ijp-18-104-g001.jpg
F1
An upper GI endoscopy revealed multiple discrete whitish-to-yellowish patches measuring less than 1 cm in size in the gastric antrum (Figure 1).
Widening of foveolae by sheets of xanthoma cells. (H&E; 10X). Inset: High power view showing xanthoma cells (H&E; 40X).
ijp-18-104-g002.jpg
PMC10293599_01_ijp-18-104-g002.jpg
F2
Microscopic examination of the gastric biopsy showed a widening of foveolae by sheets of polygonal cells with abundant foamy cytoplasm and bland central nucleus (Figure 2).
Xanthoma cells are PAS negative (40 X).
ijp-18-104-g003.jpg
PMC10293599_01_ijp-18-104-g003.jpg
F3
The foamy cells showed a negative reaction on Periodic acid -Schiff (PAS) staining (Figure 3).
Immunohistochemical staining with CD68 showing diffuse cytoplasmic staining (40X)
ijp-18-104-g004.jpg
PMC10293599_01_ijp-18-104-g004.jpg
F4