PMC9371881_01
Image of the patient's bilateral lower legs demonstrating symmetrically distributed small, red, violaceous petechiae.
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fig1
An 80-year-old male with a history of immune thrombocytopenic purpura (ITP) presented for evaluation of multiple small, red, violaceous petechiae involving the bilateral dorsal feet, legs, thighs, buttocks, and arms (Figures 1and 2) that appeared 72 hours after his first dose of the vaccine.
Image of the patient's back demonstrating symmetrically distributed small, red, violaceous petechiae.
CRIDM2022-1469410.002.jpg
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fig2
An 80-year-old male with a history of immune thrombocytopenic purpura (ITP) presented for evaluation of multiple small, red, violaceous petechiae involving the bilateral dorsal feet, legs, thighs, buttocks, and arms (Figures 1and 2) that appeared 72 hours after his first dose of the vaccine.
H&E (10x) shows a perivascular infiltrate with fibrinoid changes consistent with leukocytoclastic vasculitis.
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fig3
Histology showed a perivascular lymphocytic infiltrate with extravasated red blood cells suggestive of vascular injury (Figures 3 and 4).
H&E (40x) shows early fibrinoid changes and scattered neutrophils consistent with leukocytoclastic vasculitis.
CRIDM2022-1469410.004.jpg
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fig4
Histology showed a perivascular lymphocytic infiltrate with extravasated red blood cells suggestive of vascular injury (Figures 3 and 4).