PMC7457521_01
18F-DOPA PET/CT Pancreatic Imaging. 18F-DOPA PET/CT imaging in the case described demonstrates diffuse pancreatic uptake (a-c). A coronal maximal intensity projection (MIP) image with OSEM reconstruction is shown at 30-45 min after radionucleotide injection (a) with merged coronal (b) and axial (c) PET and CT images. The previous patient with the same KCNJ11 mutation demonstrated similar findings on 18F-DOPA PET-CT scanning with diffuse uptake throughout the pancreas at 44 min post-injection on both MIP and merged PET-CT coronal images (d, e)
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Fig1
Similar scan findings to our case were noted (Fig. 1D-E).
PMC7457521_02
18F-DOPA PET/CT Pancreatic Imaging. 18F-DOPA PET/CT imaging in the case described demonstrates diffuse pancreatic uptake (a-c). A coronal maximal intensity projection (MIP) image with OSEM reconstruction is shown at 30-45 min after radionucleotide injection (a) with merged coronal (b) and axial (c) PET and CT images. The previous patient with the same KCNJ11 mutation demonstrated similar findings on 18F-DOPA PET-CT scanning with diffuse uptake throughout the pancreas at 44 min post-injection on both MIP and merged PET-CT coronal images (d, e)
13633_2020_86_Fig1_HTML.jpg
PMC7457521_02_13633_2020_86_Fig1_HTML.jpg
Fig1
Similar scan findings to our case were noted (Fig. 1D-E).
PMC7457521_03
Focal CHI Lesion Histology. (a) Haematoxylin & eosin and (b) insulin staining of the resected pancreas revealed a 4.9 x 1.7 mm nodular lesion consistent with the presence of a focal lesion. Size marker is equivalent to 0.5 mm
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Fig2
The histology demonstrated islands of endocrine cells, predominantly insulin and proinsulin positive, interspersed by bands of fibrous tissue and some acinar cells, consistent with a focal lesion (Fig. 2).