PMC6217876_01
PMC6217876_02
Sinusoidal distension and congestion with many crescent-shaped or needle-shaped red cells and sickle cells (arrowheads) are seen in this field, along with mild steatosis in hepatocytes (H&E, 500x, before reperfusion).
CRIT2018-5154136.001.jpg
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fig1
The liver biopsy protocol included preclamping and prerevascularization biopsy with mild siderosis and steatosis, hepatocyte ballooning, rare canalicular cholestasis, and moderate sinusoidal congestion with predominance of drepanocytes (Figure 1).
Kupffer cell erythrophagocytosis (arrows) and scarce sickle cells (arrowheads) in sinusoids, as well as some hepatocellular vacuolar degeneration (H&E, 500x).
CRIT2018-5154136.002.jpg
PMC6217876_02_CRIT2018-5154136.002.jpg
fig2
Kupffer cell erythrophagocytosis and scarce sickle cells were still seen in a biopsy performed on the following day (Figure 2), along with some ischemic areas.