PMC8267028_01
The evolution of pulmonary infiltrates in computed tomography (CT). There are extensive bilateral airspace consolidations and ground-glass opacities (A). CT after tocilizumab therapy shows significant improvement (B). CT on second admission reveals further regression of pulmonary changes (C).
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PMC8267028_01_10.1177_23247096211029787-fig1.jpg
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His chest CT revealed extensive bilateral airspace consolidations and ground-glass opacities (Figure 1A), and the interleukin-6 inhibitor tocilizumab at 8 mg/kg (800 mg) was administered as a single infusion on day 7. After tocilizumab infusion, the patient's state significantly improved, and on day 26, he was discharged from hospital after confirming significant improvement in his CT scan (Figure 1B) and 2 negative SARS-CoV-2 RT-PCR from nasopharyngeal swabs. CT showed further regression of pulmonary changes (Figure 1C). CSF examination revealed pleocytosis (18/mm3), a high protein level of 115 mg/dL, and no oligoclonal immunoglobulin G bands.