PMC8272517_01
Clinical photograph of I. O lesions
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F1
On oral examination, the swelling was observed in relation to lower left first molar region mucosa with bone involvement and also in lower left anterior region gingivae [Figures 1 and 2].
Clinical photograph of I. O lesions
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F2
On oral examination, the swelling was observed in relation to lower left first molar region mucosa with bone involvement and also in lower left anterior region gingivae [Figures 1 and 2].
Orthopantomogram of the patient showing patchy radiolucency with irregular margins in the left anterior region extending as poorly defined radiolucency into the body of mandible region
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F3
Radiograph showed an irregular, radiolucent lesion extending from the lower left central incisor to the left first molar in the mandibular alveolar region extending as poorly defined radiolucency into the body of the mandible region [Figure 3].
H & E stained sections in x5 magnification showing diffuse presence of round cells in deep connective tissue
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F4
However, deep connective tissue showed an exuberant presence of dark, large lymphocyte-like cells and vacuolar histiocyte-like cells which made the oral pathologist suspect a lymphoma or probably a leukemia.(Figures 4-8: different magnifications & microscopic fields).
H & E stained sections in x5 magnification showing diffuse presence of round cells in deep connective tissue
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F5
However, deep connective tissue showed an exuberant presence of dark, large lymphocyte-like cells and vacuolar histiocyte-like cells which made the oral pathologist suspect a lymphoma or probably a leukemia.(Figures 4-8: different magnifications & microscopic fields).
H & E stained sections in x10 magnification showing diffuse presence of two different morphologies of cell populations in deep connective tissue
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F6
However, deep connective tissue showed an exuberant presence of dark, large lymphocyte-like cells and vacuolar histiocyte-like cells which made the oral pathologist suspect a lymphoma or probably a leukemia.(Figures 4-8: different magnifications & microscopic fields).
H & E stained sections in x10 magnification showing diffuse presence of two different morphologies of cell populations in deep connective tissue
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F7
However, deep connective tissue showed an exuberant presence of dark, large lymphocyte-like cells and vacuolar histiocyte-like cells which made the oral pathologist suspect a lymphoma or probably a leukemia.(Figures 4-8: different magnifications & microscopic fields).
H & E stained sections in x40 magnification showing diffuse presence of two different morphologies of cell populations in deep connective tissue
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F8
However, deep connective tissue showed an exuberant presence of dark, large lymphocyte-like cells and vacuolar histiocyte-like cells which made the oral pathologist suspect a lymphoma or probably a leukemia.(Figures 4-8: different magnifications & microscopic fields).
Cytokeratin-high molecular weight negative staining of the tissue cells
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F9
CK7 and CK-HMW were negative, and P63 had a very mild and patchy positivity [Figures 9-11].
Cytokeratin 7 negative staining of the tissue cells
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F10
CK7 and CK-HMW were negative, and P63 had a very mild and patchy positivity [Figures 9-11].
P63 mild positivity of tumor tissue cells
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F11
CK7 and CK-HMW were negative, and P63 had a very mild and patchy positivity [Figures 9-11].