PMC9174507_01
(A) The computed tomography image showed inflammatory changes of the breastbone; (B) The "bull's head sign" on bony scintigraphy; (C) Palmoplantar pustulosis (PPP) on the patient's palms and feet before using tofacitinib; (D, E). PPP on the patient's palms and feet after using tofacitinib for one month and two months.
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Radiography showed grade 2 to 3 bilateral sacroiliitis and MRI of the spine showed inflammation at the attachment point ( Figure S1 ). Through comprehensive clinical assessment, a diagnosis of SAPHO syndrome was established ( Figures 1A-C ). The patient's rash subsided significantly after 1 month ( Figures 1D, E ), and the chest and back pain was further relieved ( Figure 2 ).
Treatment options and outcomes for patients from 2012 to 2021.
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Free inflammatory exudates were also observed ( Figure S2 ). The patient's rash subsided significantly after 1 month ( Figures 1D, E ), and the chest and back pain was further relieved ( Figure 2 ).