PMC9233607_01
CT chest showing involvement of the right lower paratracheal lymphnodes (Station 4R).
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fig1
Multiple lytic lesions in the dorsal vertebrae and a sclerotic focus in the manubrium sternum were identified (Figures 1 and 2).
CT chest. (a) Confluent prevascular nodal mass measuring 4.1 x 2.4 cm. (b) Right hilar lymph node measuring 2.5 x 3.1 cm.
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fig2
Multiple lytic lesions in the dorsal vertebrae and a sclerotic focus in the manubrium sternum were identified (Figures 1 and 2).
Diff-Quik smear shows clusters of cohesive neoplastic, epithelioid cells with a small amount of cytoplasm (a). The alcoholol-fixed smears demonstrate individual and clustered neoplastic cells with coarse chromatin, ill-defined borders, and nuclear grooves (c, d). The corresponding cellblock material is shown in (b).
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fig3
Cytoplasmic extensions were appreciated in some areas (Figure 3).
GFAP is immunoreactive in the tumor cells (a). (b) Strong positivity for synaptophysin. S100 protein immunostain demonstrates strong and diffuse positivity (c). Keratin is negative (not shown).
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fig4
Tumor cells, however, were immunoreactive for GFAP, synaptophysin, and S100 protein (Figure 4).
Treatment timeline. Abbreviations: CCRT: concurrent chemoradiation; Adj TMZ: adjuvant temozolomide; XRT: radiation therapy; DD: dose dense.
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fig5
Treatment timeline is shown in Figure 5.