PMC4949179_01
Clinical manifestation and histopathology. a Clinical manifestation with painful, swollen and palpable purpuric skin eruptions on both sides of her lower legs. b Histopathological examination exhibiting neutrophil-rich leukocytoclastic vasculitis in upper dermis with extravasation of red blood cells into dermis (hematoxylin and eosin stain; original magnification x100). c Clinical manifestation of reappearance of purpura with cellulitis
40064_2016_2792_Fig1_HTML.jpg
PMC4949179_01_40064_2016_2792_Fig1_HTML.jpg
Fig1
A 78-year-old woman visited our hospital with a fever over 38  and for evaluation of her painful, swollen and palpable purpuric skin eruptions on her lower legs (Fig. 1a). A skin biopsy specimen taken from a purpuric lesion on her leg revealed that neutrophil-rich leukocytoclastic vasculitis in upper dermis with extravasation of red blood cells into the dermis (Fig. 1b). When cellulitis re-emerged on her lower legs, a generalized purpuric eruption reappeared on her upper arms, legs and lower abdomen (Fig. 1c).