PMC6346974_01
Right: submassive coagulative necrosis involving centrilobular zone 3. The necrotic zone is surrounded by hepatocytes with typical viral inclusions. There is minimal inflammation around the necrosis. Left: the centrolobular vein is spared
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PMC6346974_01_982_Fig1.jpg
f1-982-1-6357-1-10-20181126
Immunohistochemical analysis identified the infection as herpes simplex virus (HSV) hepatitis (Figs. 1-4).
Viral nuclear inclusions
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PMC6346974_01_982_Fig2.jpg
f2-982-1-6357-1-10-20181126
Immunohistochemical analysis identified the infection as herpes simplex virus (HSV) hepatitis (Figs. 1-4).
Immunostaining for herpes simplex shows infected cells in randomly distributed areas of coagulative necrosis
982_Fig3.jpg
PMC6346974_01_982_Fig3.jpg
f3-982-1-6357-1-10-20181126
Immunohistochemical analysis identified the infection as herpes simplex virus (HSV) hepatitis (Figs. 1-4).
Immunostaining for herpes simplex (high magnification)
982_Fig4.jpg
PMC6346974_01_982_Fig4.jpg
f4-982-1-6357-1-10-20181126
Immunohistochemical analysis identified the infection as herpes simplex virus (HSV) hepatitis (Figs. 1-4).