PMC7307616_01
(a) Apical four-chamber view of transthoracic echocardiogram showing a left atrial mass (*) protruding into the left atrial cavity and across the mitral valve into the left ventricle. (b) Transesophageal echocardiogram showing a large, broad-based, multilobed, irregular shaped, heterogeneous mass with multiple hypoechoic areas (*) arising from the posterosuperior aspect of interatrial septum and infiltrating into the septum and surrounding myocardium (arrows). LA = Left atrium, LV = Left ventricle, RA = Right atrium, RV = Right ventricle
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F1
Transthoracic echocardiogram revealed an echogenic mass measuring 48 mm x 14 mm arising from the left atrial roof and protruding into the left atrial cavity [Figure 1a and Video 1]. The mass infiltrated into the septum, surrounding myocardium, and also protruded into the left atrial and left ventricular cavities causing moderate functional mitral stenosis [Figure 1b and Video 2].
(a) Gross specimen of the excised mass revealing a cherry-red colored, elongated and multilobed mass. (b) Hypercellular areas on histopathology examination showing sheets of neoplastic cells with moderate nuclear atypia, pleomorphism, and atypical mitoses. (c) Hypocellular areas on histopathology examination showing myxoid degeneration with thin-walled staghorn blood vessel proliferations
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F2
The mass infiltrated into the septum, surrounding myocardium, and also protruded into the left atrial and left ventricular cavities causing moderate functional mitral stenosis [Figure 1b and Video 2]. The hypocellular areas showed myxoid degeneration with thin-walled staghorn blood vessel proliferation, whereas the hypercellular areas revealed sheets of neoplastic cells with moderate nuclear atypia, pleomorphism, and atypical mitosis [Figure 2a-c].
Transthoracic echocardiogram revealing a 29 mm x 22 mm heterogeneous mass (arrows) attached to the interatrial septum and protruding into the left atrial cavity. Both the mitral leaflets are thickened. LA = Left atrium, LV = Left ventricle, RA = Right atrium, RV = Right ventricle
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F3
Both the mitral leaflets were thickened with markedly restricted movement and causing mitral stenosis which suggested infiltration of the tumor [Figure 3].