PMC9470944_01
A growth curve showing stature and weight for age. Dotted line in red, weight; solid line in blue, height.
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F2
The growth curves of the patient are shown in Figure 2.
PMC9470944_02
Nocturnal pulse oximetry, TcPCO2 evolution, and sleep stage presentation in PSG, starting at 1 a.m. of the BPAP pressure titration. Hypoventilation was seen (SpO2 between 60 and 98%; PCO2 maximum 75 mmHg) for 4 h during the night, accompanied by sleep structure disruption (recurrent arousal and inability to deep sleep). Sleep stage: W, wake; R, REM stage, N1, NREM stage 1; N2, NREM stage 2; N3, NREM stage 3.
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F1
However, hypoxemia (SpO2 < 90%) and hypercapnia (TcPCO2 > 70 mmHg) still appeared during stage N3 of the first two sleep cycles (Supplementary Figure 1) without much change in ventilator settings.
Timeline of symptoms and progression.
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F3
A timeline of the symptom and progress was shown in Figure 3.