PMC4816429_01
A-C Representative figures of case 1. A, B A well-circumscribed, superficial dermal proliferation of plump, spindled myoid cells arranged concentrically around vessels. A HE. x4. B HE. x20. C A patchy and weak immunohistochemical staining of the lesional cells with SMA. x10. D-F Case 2. D, E An ill-defined proliferation of uniformly, ovoid, spindled cells arranged in short fascicles around blood vessels in the superficial dermis. D HE. x4. E HE. x20. F A diffuse and strong immunohistochemical staining of the lesional cells with SMA. x10. G-I Case 3. G, H An ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels. G HE. x4. H HE. x20. I A focal and weak immunohistochemical staining of the lesional cells with SMA. x20.
dpa-0002-0009-g01.jpg
PMC4816429_03_dpa-0002-0009-g01.jpg
F1
Histopathologic examination of a punch biopsy revealed an ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels (fig. 1G, H). Immunohistochemical stains revealed focal positive staining of the lesional cells with SMA (fig. 1I) and negative staining with S100 protein, desmin, h-caldesmon, pancytokeratin, CD31, and CD34.
PMC4816429_02
A-C Representative figures of case 1. A, B A well-circumscribed, superficial dermal proliferation of plump, spindled myoid cells arranged concentrically around vessels. A HE. x4. B HE. x20. C A patchy and weak immunohistochemical staining of the lesional cells with SMA. x10. D-F Case 2. D, E An ill-defined proliferation of uniformly, ovoid, spindled cells arranged in short fascicles around blood vessels in the superficial dermis. D HE. x4. E HE. x20. F A diffuse and strong immunohistochemical staining of the lesional cells with SMA. x10. G-I Case 3. G, H An ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels. G HE. x4. H HE. x20. I A focal and weak immunohistochemical staining of the lesional cells with SMA. x20.
dpa-0002-0009-g01.jpg
PMC4816429_03_dpa-0002-0009-g01.jpg
F1
Histopathologic examination of a punch biopsy revealed an ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels (fig. 1G, H). Immunohistochemical stains revealed focal positive staining of the lesional cells with SMA (fig. 1I) and negative staining with S100 protein, desmin, h-caldesmon, pancytokeratin, CD31, and CD34.
PMC4816429_03
A-C Representative figures of case 1. A, B A well-circumscribed, superficial dermal proliferation of plump, spindled myoid cells arranged concentrically around vessels. A HE. x4. B HE. x20. C A patchy and weak immunohistochemical staining of the lesional cells with SMA. x10. D-F Case 2. D, E An ill-defined proliferation of uniformly, ovoid, spindled cells arranged in short fascicles around blood vessels in the superficial dermis. D HE. x4. E HE. x20. F A diffuse and strong immunohistochemical staining of the lesional cells with SMA. x10. G-I Case 3. G, H An ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels. G HE. x4. H HE. x20. I A focal and weak immunohistochemical staining of the lesional cells with SMA. x20.
dpa-0002-0009-g01.jpg
PMC4816429_03_dpa-0002-0009-g01.jpg
F1
Histopathologic examination of a punch biopsy revealed an ill-circumscribed proliferation of plump, spindled to round cells closely surrounding numerous dilated and branching endothelial cell-lined vessels (fig. 1G, H). Immunohistochemical stains revealed focal positive staining of the lesional cells with SMA (fig. 1I) and negative staining with S100 protein, desmin, h-caldesmon, pancytokeratin, CD31, and CD34.