PMC3420722_01
Flexible laryngoscopy showing an obtrusive tumor localized in the right false cord (arrows).
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fig1
Flexible laryngoscopy revealed a conspicuous lesion localized in the right false cord (Figure 1), and the vocal fold movement was limited.
CT-scan (a) and MRI (b) showing a swelling of the right false cord (arrows) with involvement of the paraglottic space and without a sign of significant lymphadenopathy.
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fig2
Computerized tomography (CT) and magnetic resonance imaging (MRI) showed swelling of the right false cord without significant cervical lymphadenopathy and demonstrated that the paraglottic space was involved with no sign of thyroid cartilage erosion (Figure 2).
Histopathological examination by HE staining (a) reveals cluster of undifferentiated small cells. Immunohistochemical analyses of LCA (b), EMA (c), and chromogranin A (d) show no significant positive staining (original magnification; x400).
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fig3
Histological examination of a biopsied specimen revealed sheets of undifferentiated small atypical cells with minimal cytoplasm (Figure 3(a)), which is similar to the characteristic of pulmonary SmCC. Immunohistochemical analyses revealed that neoplastic cells did not express leukocyte common antigen (LCA), epithelial membrane antigen (EMA), and chromogranin A (Figures 3(b), 3(c), and 3(d)).