PMC5198856_01
A, Routine hematoxylin-eosin staining. B, Melan-A immunohistochemical staining. (A and B, Original magnifications: x13).
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Routine hematoxylin and eosin staining found a well-circumscribed, noninflammatory, dermal mass with atypical nested melanocytes, frequent mitotic figures, and no epidermal connection (Fig 1, A). The dermal mass was strongly positive for S-100 and melan-A (Fig 1, B) and demonstrated similar cytologic features as the patient's primary tumor.