PMC3866881_01
MRI findings at initial presentation (upper row) and follow-up (lower row). (a)-(b) Axial FLAIR images, taken at the levels of the hippocampi, mid lateral ventricles, and centrum semiovale, demonstrate confluent areas of abnormal high signal in the deep white matter with sparing of the subcortical white matter and overlying cortex. (d)-(e) Axial FLAIR images, at similar levels to (a)-(b), demonstrate marked decrease in the abnormal signal in the cerebral white matter. (c) shows small areas of restricted diffusion in the left greater than right medial parietal and bilateral frontal lobes, with apparent diffusion coefficient (ADC) correlation (f).
CRIM.NM2013-536978.001.jpg
PMC3866881_01_CRIM.NM2013-536978.001.jpg
fig1
Small areas of restricted diffusion were detected in the left greater than right medial parietal and bilateral frontal lobes, with apparent diffusion coefficient (ADC) correlation (Figure 1). T2 signals in the deep white matter, cerebellum, and pons significantly improved while small areas of hyperintense signal changes were still observed in the bilateral parieto-occipital regions (Figure 1). The patient's mental status returned to baseline and he had no further seizure activity for at least 4 years of follow-up.
PMC3866881_02
Magnetic resonance imaging findings in case 2 at initial presentation (upper row) and follow-up (lower row). (a)-(c) Axial FLAIR images, taken at the levels of the hippocampi, mid lateral ventricles, and centrum semiovale, demonstrate confluent areas of abnormal high signal in the deep white matter with sparing of the subcortical white matter and overlying cortex. (d)-(f) Axial FLAIR images, at similar levels to (a)-(c), demonstrate marked decrease in the abnormal signal in the cerebral white matter.
CRIM.NM2013-536978.002.jpg
PMC3866881_02_CRIM.NM2013-536978.002.jpg
fig2
An MRI of the brain demonstrated confluent T2 signal abnormalities in the bilateral deep white matter region sparing the corpus callosum (Figure 2). Five months later, a follow-up MRI showed a marked reduction of the signal abnormalities previously seen in the deep white matter region (Figure 2).