PMC3135081_01
Lateral and dorsal view of a one-year-old female goat with sarcoptic mange, showing the typical skin lesions of the disease and the emaciation of the animal.
VMI2011-476348.001.jpg
PMC3135081_01_VMI2011-476348.001.jpg
fig1
Thessaloniki, Greece), with a generalized and diffuse skin disease that was highly pruritic characterized by alopecia-hypotrichosis, erythema, hyperpigmentation, excoriations, thick crusts, skin folding, and lichenification (Figure 1(a)). These animals were also emaciated (Figure 1(b)) and anorectic with no actual milk yield.
Skin biopsy obtained from lesional skin, in which a hyperplastic superficial dermatitis, along with several Sarcoptes  scabiei mites embedded within the hyperkeratotic stratum corneum, is shown (H&E 50x).
VMI2011-476348.002.jpg
PMC3135081_01_VMI2011-476348.002.jpg
fig2
The ensuing histopathological examination disclosed a severe orthokeratotic and laminated hyperkeratosis, epidermal acanthosis, and spongiosis as well as superficial perivascular to interstitial dermatitis with a strong eosinophilic component within the cellular infiltrate; several mites were also found embedded within the stratum corneum (Figure 2).