PMC7370326_01
Twice colonoscopy showed segmental inflammation and shallow ulcers from distal ileum to sigmoid colon.
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On 13 October 2016, colonoscopy showed multiple segmental colon ulcers, which was considered as Crohn's disease or tuberculosis (Figure 1(a) and (b)). On 30 October, IBD was considered by colonoscopy, but it was not confirmed (Figure 1(a) and (b)).
Inflammatory cells infiltration in intestinal wall and there were multiple granulomatous lesions without obvious caseous necrosis.
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It tended to be Crohn's disease, but tuberculosis was not excluded (Figure 2).
CT and CTE showed multiple segmental thickening of the intestinal wall.
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The CTE of the small intestine showed that ileocecus and distal ileum were thickened and strengthened obviously after injection, so that the patient was conformed to Crohn's disease (Figure 3(c) and (d)).
T. marneffei's specific sausage-like cells and cross-walls can be observed by PAS staining and GMS staining.
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On 7 November, Southern Hospital Pathology Consultation Report described that a large number of tissue cells and multinuclear giant cells were seen in the lamina propria of ileum mucosa, and fungal spores were found in tissue cells, so that he was diagnosed as talaromycosis (Figure 4).