PMC8102820_01
Magnetic Resonance Imaging Findings. (A-C) At first onset, MRI demonstrated patchy lesions in the medulla oblongata and dorsal pons; (D-F) At first recurrence, MRI demonstrated multiple lesions in the brain; (G, H) At second onset, MRI demonstrated pons lesions, consistent with the diagnosis of multiple sclerosis; (I-K) Before teriflunomide administration, MRI demonstrated new punctate enhancing lesions in the left frontal lobe and abnormal signals in the thoracic spinal cord at T6-7 of the skull and spinal cord; (L-N) After 6 months of teriflunomide use, MRI demonstrated that the lesions were reduced, especially in the spinal cord; (O, P) After 1 year of teriflunomide use, MRI demonstrated that the patient's lesions were reduced. The arrowhead showing lesions in MRI. MRI, Magnetic resonance imaging.
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Babinski signs, positive Romberg sign, and waddling gait. Besides, the magnetic resonance imaging (MRI) test revealed that lesions in medulla oblongata and pontine tegmentum ( Figures 1A-C ), the findings of CSF disclosed positive anti-NMDAR antibody ( Table 1 ), electroencephalogram showed mild abnormal electroencephalogram (slow basic rhythm), and the ultrasound examination revealed polycystic ovary. The MRI test found that there were new lesions in the brainstem, periventricular, and corpus callosum ( Figures 1G, H ), the evoked potential test presented that the central segment of bilateral auditory pathway and the bilateral visual pathway were both injured, and OCB was positive in CSF. Her MRI test showed new spotted lesions in the left frontal lobe and a lesion in the thoracic spinal cord of thoracic spine 6-7 ( Figures 1I-K ) and her EDSS was 2.0.