PMC10124559_01
Per operatory image of the tumor in the left external auditory canal (scale bar= 2cm).
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Photomicrographs of the pleomorphic adenoma. A and B show tubules, ducts, and cysts embedded in a chondromyxoid stroma. (H&E, 40X); C and D - Photomicrographs of cellular foci in the pleomorphic adenoma showing tubules lined by bilayered epithelium. (H&E, 40X and 100X respectively).
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The epithelial component is formed by tubules, nests and acinar structures admixed with myoepithelial cells and is set in a myxoid stroma. (Figures 2A and 2B).
High power microscopy of a cellular area of the pleomorphic adenoma showing tubules and acinar structures lined by bilayered epithelium. (H&E, 200X).
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Photomicrograph of the tumor. A - Immunohistochemistry reaction for p63 showing positivity in the myoepithelial cells, but negative in glandular epithelial cells (200X); B - Immunohistochemistry reaction for CK7 highlighting the luminal layer while the abluminal myoepithelial cells are negative (200X).
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The luminal cells expressed cytokeratin 7 (Figure 4A), while peripheral (basal) cells expressed p63 (Figure 4B).