PMC8514759_01
On admission, slight ptosis was observed, and adduction failure of the right eye was observed (left, upper panels; red circles). On day 17, adduction failure of the left eye was observed in addition to that of the right eye. Vertical movement was also impaired in both eyes. Slight ptosis was observed in both eyes, and the right eye was completely close (right, upper panels; red circles). On day 38 after steroid therapy, ptosis and vertical movements in both eyes were recovered but horizontal movements of both eyes were not altered (left, lower panels). On day 129, ptosis and vertical movements in both eyes were completely normalized and horizontal movements of both eyes were almost completely recovered (right, lower panels).
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F1
Slight ptosis was observed, and failure of adduction was observed in the right eye (Figure 1). Slight ptosis was observed in both eyes, and the right eye was completely close (Figure 1). On day 38, ptosis and vertical movements in both eyes were recovered but horizontal movements of both eyes were not altered (Figure 1). On day 129, ptosis and vertical and horizontal movements in both eyes were almost completely recovered (Figure 1).
(Upper) In orbital magnetic resonance imaging before starting treatment, some high signal was detected in both extraocular muscles, indicating that inflammation extended into the extraocular muscles in this subject (both panels; yellow arrows). (Lower) After the steroid pulse therapy, signal intensity in extraocular muscle tended to be weakened, and orbital fat mass was moderately reduced.
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F2
In orbital MRI, some high signal was detected in both extraocular muscles, indicating that inflammation extended into the extraocular muscles in this subject (Figure 2). After the steroid pulse therapy, signal intensity in extraocular muscle tended to be weakened, and orbital fat mass was moderately reduced (Figure 2).