PMC6066802_01
Histopathologic section (hematoxylin-eosin, original magnification x100).
(A) Case 1:gastric ulcer edge biopsy showing caseating granuloma (large
arrow) and Langerhans giant cell (small arrow). (B) Case 2:duodenal
erosion biopsy showing granuloma formation (black arrow). White arrow
showing Langerhans cell. (C) Case 3:ill-formed Langerhans giant cells
with granuloma formation. (D) Case 4:stomach cardia growth biopsy
showing caseating granuloma and Langerhans giant cell.
10.1177_1179552218790566-fig2.jpg
PMC6066802_04_10.1177_1179552218790566-fig2.jpg
fig2-1179552218790566
Biopsy of gastric lesion showed caseating epitheloid cell granuloma with Langerhans giant cell in lamina propria (Figure 2D).
Upper gastrointestinal endoscopy images after taking anti tubercular
therapy. (A) Healed gastric ulcer in case 1 after 4 months of AKT. (B)
Healed nodularity with ulceration at D1 and D2 junction in case 2 after
6 months of AKT. (C) Healed ulcer proliferative growth and sinus in case
4 after 9 months of AKT.. Abbreviation: AKT, anti kochs treatment.
10.1177_1179552218790566-fig3.jpg
PMC6066802_04_10.1177_1179552218790566-fig3.jpg
fig3-1179552218790566
Repeat endoscopy at 9 months showed complete healing of the growth-like lesion (Figure 3C).
PMC6066802_02
Upper gastrointestinal endoscopy on admission. (A) Nodularity with
ulceration at D1 and D2 junction in case 2. (B) Erosions in duodenum
(D1) in case 3. (C) Ulcer proliferative growth with sinus formation in
cardia of stomach in case 4.
10.1177_1179552218790566-fig1.jpg
PMC6066802_04_10.1177_1179552218790566-fig1.jpg
fig1-1179552218790566
An ulceronodular friable lesion (highly suspicious of malignancy) in the gastric cardia with a suspicious adjacent opening suggestive of a sinus tract or a fistula was seen on upper GI endoscopy (Figure 1C).
Histopathologic section (hematoxylin-eosin, original magnification x100).
(A) Case 1:gastric ulcer edge biopsy showing caseating granuloma (large
arrow) and Langerhans giant cell (small arrow). (B) Case 2:duodenal
erosion biopsy showing granuloma formation (black arrow). White arrow
showing Langerhans cell. (C) Case 3:ill-formed Langerhans giant cells
with granuloma formation. (D) Case 4:stomach cardia growth biopsy
showing caseating granuloma and Langerhans giant cell.
10.1177_1179552218790566-fig2.jpg
PMC6066802_04_10.1177_1179552218790566-fig2.jpg
fig2-1179552218790566
Biopsy of gastric lesion showed caseating epitheloid cell granuloma with Langerhans giant cell in lamina propria (Figure 2D).
Upper gastrointestinal endoscopy images after taking anti tubercular
therapy. (A) Healed gastric ulcer in case 1 after 4 months of AKT. (B)
Healed nodularity with ulceration at D1 and D2 junction in case 2 after
6 months of AKT. (C) Healed ulcer proliferative growth and sinus in case
4 after 9 months of AKT.. Abbreviation: AKT, anti kochs treatment.
10.1177_1179552218790566-fig3.jpg
PMC6066802_04_10.1177_1179552218790566-fig3.jpg
fig3-1179552218790566
Repeat endoscopy at 9 months showed complete healing of the growth-like lesion (Figure 3C).
PMC6066802_03
Upper gastrointestinal endoscopy on admission. (A) Nodularity with
ulceration at D1 and D2 junction in case 2. (B) Erosions in duodenum
(D1) in case 3. (C) Ulcer proliferative growth with sinus formation in
cardia of stomach in case 4.
10.1177_1179552218790566-fig1.jpg
PMC6066802_04_10.1177_1179552218790566-fig1.jpg
fig1-1179552218790566
An ulceronodular friable lesion (highly suspicious of malignancy) in the gastric cardia with a suspicious adjacent opening suggestive of a sinus tract or a fistula was seen on upper GI endoscopy (Figure 1C).
Histopathologic section (hematoxylin-eosin, original magnification x100).
(A) Case 1:gastric ulcer edge biopsy showing caseating granuloma (large
arrow) and Langerhans giant cell (small arrow). (B) Case 2:duodenal
erosion biopsy showing granuloma formation (black arrow). White arrow
showing Langerhans cell. (C) Case 3:ill-formed Langerhans giant cells
with granuloma formation. (D) Case 4:stomach cardia growth biopsy
showing caseating granuloma and Langerhans giant cell.
10.1177_1179552218790566-fig2.jpg
PMC6066802_04_10.1177_1179552218790566-fig2.jpg
fig2-1179552218790566
Biopsy of gastric lesion showed caseating epitheloid cell granuloma with Langerhans giant cell in lamina propria (Figure 2D).
PMC6066802_04
Upper gastrointestinal endoscopy on admission. (A) Nodularity with
ulceration at D1 and D2 junction in case 2. (B) Erosions in duodenum
(D1) in case 3. (C) Ulcer proliferative growth with sinus formation in
cardia of stomach in case 4.
10.1177_1179552218790566-fig1.jpg
PMC6066802_04_10.1177_1179552218790566-fig1.jpg
fig1-1179552218790566
An ulceronodular friable lesion (highly suspicious of malignancy) in the gastric cardia with a suspicious adjacent opening suggestive of a sinus tract or a fistula was seen on upper GI endoscopy (Figure 1C).
Histopathologic section (hematoxylin-eosin, original magnification x100).
(A) Case 1:gastric ulcer edge biopsy showing caseating granuloma (large
arrow) and Langerhans giant cell (small arrow). (B) Case 2:duodenal
erosion biopsy showing granuloma formation (black arrow). White arrow
showing Langerhans cell. (C) Case 3:ill-formed Langerhans giant cells
with granuloma formation. (D) Case 4:stomach cardia growth biopsy
showing caseating granuloma and Langerhans giant cell.
10.1177_1179552218790566-fig2.jpg
PMC6066802_04_10.1177_1179552218790566-fig2.jpg
fig2-1179552218790566
Biopsy of gastric lesion showed caseating epitheloid cell granuloma with Langerhans giant cell in lamina propria (Figure 2D).
Upper gastrointestinal endoscopy images after taking anti tubercular
therapy. (A) Healed gastric ulcer in case 1 after 4 months of AKT. (B)
Healed nodularity with ulceration at D1 and D2 junction in case 2 after
6 months of AKT. (C) Healed ulcer proliferative growth and sinus in case
4 after 9 months of AKT.. Abbreviation: AKT, anti kochs treatment.
10.1177_1179552218790566-fig3.jpg
PMC6066802_04_10.1177_1179552218790566-fig3.jpg
fig3-1179552218790566
Repeat endoscopy at 9 months showed complete healing of the growth-like lesion (Figure 3C).