PMC6036769_01
Clinical appearance of lesion
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F1
On palpation, it was indurated without tenderness and discharge [Figure 1].
H and E, x4
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F2
Hence, the diagnosis of LCH was made based on morphologic findings in microscopic examination [Figures 2-4] and confirmed by immunohistochemical staining which revealed the aggregation of S100 and CD1apositive tumoral cells [Figures 5 and 6].
H and E, another picture
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F3
Hence, the diagnosis of LCH was made based on morphologic findings in microscopic examination [Figures 2-4] and confirmed by immunohistochemical staining which revealed the aggregation of S100 and CD1apositive tumoral cells [Figures 5 and 6].
H and E, invasion of the epidermis by small aggregation of large ovoid cells with abundant eosinophilic cytoplasm and reniform nucleus
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F4
Hence, the diagnosis of LCH was made based on morphologic findings in microscopic examination [Figures 2-4] and confirmed by immunohistochemical staining which revealed the aggregation of S100 and CD1apositive tumoral cells [Figures 5 and 6].
Immunohistochemical staining with S100 marker
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F5
Hence, the diagnosis of LCH was made based on morphologic findings in microscopic examination [Figures 2-4] and confirmed by immunohistochemical staining which revealed the aggregation of S100 and CD1apositive tumoral cells [Figures 5 and 6].
Immunohistochemical staining with CD1a marker
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F6
Hence, the diagnosis of LCH was made based on morphologic findings in microscopic examination [Figures 2-4] and confirmed by immunohistochemical staining which revealed the aggregation of S100 and CD1apositive tumoral cells [Figures 5 and 6].