PMC8318922_01
MRI of the whole spine demonstrating S1 pathological fracture with spinal canal stenosis at S1 and S2. (A) Sagittal view (B) Axial view.
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Magnetic resonance imaging (MRI) of the spine showed extensive bone metastases with S1 pathological fracture causing spinal canal stenosis at S1 and S2 (Fig. 1a and b).
PET-CT scans of the patient during treatment. (A) Baseline before treatment: Multiple avid pelvic bone lesions including right iliac bone (SUV 9.2), sacral bone (SUV 9.2), right acetabulum (SUV 6.4), left iliac bone (SUV 7.7). (B) After 4 cycles of treatment: Partial metabolic response in left iliac bone (SUV 2.0) and sacral bone (SUV 2.1), complete metabolic response in the remaining lesions.
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There were extensive metastatic lesions at the bone and liver (Fig. 2, Fig. 3, Fig. 4A). There was a complete metabolic response of the liver lesions, and a partial metabolic response of the bony lesions (Fig. 2, Fig. 3, Fig. 4B).
PET-CT of the patient during treatment. (A) Baseline scan before treatment: Intra-hepatic avid lesions. (B) After 4 cycles of treatment: Complete metabolic response.
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There were extensive metastatic lesions at the bone and liver (Fig. 2, Fig. 3, Fig. 4A). There was a complete metabolic response of the liver lesions, and a partial metabolic response of the bony lesions (Fig. 2, Fig. 3, Fig. 4B).
Carbohydrate antigen 19-9 (Ca19-9) trend.
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There was also a significant decrease in her tumor markers - carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (Ca19-9) (Fig. 5, Fig. 6).