PMC6287048_01
Evolution of Case 1-cutaneous metastasis: (A) before TDM1 initiation, (B) after 3 courses of TDM1, (C) after 45 courses of TDM1.
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F1
It has been 45 cycles of TDM1 and the patient is still disease-free (Figure 1).
PMC6287048_02
Evolution of Case 2-cutaneous metastasis: (A) before TDM1 initiation, (B) after 4 courses of TDM1, (C) 9 months after TDM1 discontinuation.
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F2
After 9 months since TDM1 had been discontinued the patient was still disease free (Figure 2).