PMC4421355_01
Coronal MRI of a patient with ADPKD, before (A) and after (B) 6-months treatment with low-dose rapamycin. (C) Macroscopic view of the left kidney after nephrectomy.
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F1
The initial renal volume was 1026 ml and the final renal volume 785 ml, that is, a volume change of -241 ml (-23.5%) within 6 months (Figure 1A and B). In February 2008, the haematuria became life threatening and the kidney was removed (weight 1309 g) (Figure 1C).
Change in kidney volume. Rapamycin was administered from July 2006 to February 2007.
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F2
The change in kidney volume during and after rapamycin is represented in Figure 2.