PMC9794743_01
Time course of symptoms, diagnosis, and treatment.
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F1
A timeline of the symptoms and treatment are shown in Figure 1.
Representative images of the reaction of antibodies from the patients' serum with cells that express DPPX. Total IgG staining 10x (A) 40x (B), IgG2 20x (C), IgG4 20x (D).
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F2
High titres of anti-DPPX antibodies were found in serum (106) and cerebrospinal fluid (103) (Figures 2A,B). The IgG subclass distribution of anti-DPPX in both serum and cerebrospinal fluid was: IgG4>>IgG2>IgG1=IgG3 (Figures 2C,D).