PMC6458242_01
Initial CT scans. (A) Hepatoblastoma of the left hepatic lobe measuring 11 x 6.5 x 8.9 cm. (B) Neuroblastoma of the left adrenal gland measuring 2.3 x 1.6 x 3.6 cm.
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F1
Variability of neuron-specific enolase (NSE) levels during and after combined-modality therapy.
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F2
Fluctuations of NSE in the perioperative period are presented in Figure 2.
Histopathological images. (A) Hepatoblastoma, mixed epithelial-mesenchymal subtype: areas of embryonal epithelial type cells, primitive mesenchyme and osteoid formation. HE, magnification 200x. (B) Hepatoblastoma, mixed epithelial-mesenchymal subtype: fetal epithelial type cells with focal extramedullary hematopoesis and mesenchymal component represented by osteoid formation. HE, magnification 200x. (C) Neuroblastoma, Schwannian stroma:poor, differentiating subtype: scant differentiating neuroblasts and neuropil in the background. HE, magnification 200x. (D) Neuroblastoma, Schwannian stroma:poor, differentiating subtype: positive immunohistochemical reaction for synaptophysin in tumor cells cytoplasm and neuropil. Magnification 200x.
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F3
The histopathological examination of the removed liver tumor confirmed the initial diagnosis of HBL (mixed epithelial-mesenchymal subtype) (Figures 3A,B). In turn, in the material from adrenal tumor residual remnants of NBL (Schwannian stroma:poor, differentiating subtype) (synaptophysin +, NSE +) were found in the regression stage (Figures 3C,D).