PMC7403948_01
Microscopic image of leukemic lymphocytes in the peripheral blood smear.
CRIHEM2020-8822172.001.jpg
PMC7403948_01_CRIHEM2020-8822172.001.jpg
fig1
Microscopic examination of the blood smear revealed small-to-medium-sized lymphocytes that featured irregularly shaped nuclei and condensed chromatin (Figure 1).
Treatment time course for the leukemia and central nervous system involvement. ALM: alemtuzumab; CSF: cerebrospinal fluid; FC: fludarabine and cyclophosphamide; HSCT: hematopoietic stem-cell transplantation; IT: intrathecal treatment; IV: intravenous treatment; MTX: methotrexate; WBI: whole brain irradiation; and WSI: whole spine irradiation. Triplets consist of 15 mg of methotrexate, 40 mg of cytarabine, and 20 mg of prednisolone.
CRIHEM2020-8822172.002.jpg
PMC7403948_01_CRIHEM2020-8822172.002.jpg
fig2
Following these changes, the patient's lymphocyte count dropped sharply (Figure 2).