PMC3621153_01
T2W sagittal section showing tumor extending up to anal verge and involving left wall of anal canal with loss of sphincteric anatomy.
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fig1
MRI pelvis revealed a lesion involving rectum and anal canal with extension into intersphincteric plane and puborectalis (Figures 1 and 2).
T2W axial image through distal rectum showing partly endophytic (A) and partly exophytic (B) mass having intermediate signal intensity. Left puborectalis muscle is invaded, thickened, and retracted (C).
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fig2
MRI pelvis revealed a lesion involving rectum and anal canal with extension into intersphincteric plane and puborectalis (Figures 1 and 2).
Abdominoperineal resection specimen.
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fig3
The patient underwent abdominoperineal resection with end colostomy (Figures 3 and 4).
Growth in anorectal region.
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fig4
The patient underwent abdominoperineal resection with end colostomy (Figures 3 and 4).
Spindle cells arranged in fascicles and showing mild nuclear pleomorphism and mitotic activity (100x magnification).
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fig5
Mitotic figures were more than 5/50 HPF. The CD117:immunoreactive score:was 3+ in spindled cells (Figures 5 and 6).
Spindle cells showing strong immunoreactivity for CD117 on IHC (score 3+ to 4+) (100x magnification).
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fig6
The CD117:immunoreactive score:was 3+ in spindled cells (Figures 5 and 6).