PMC4609797_01
PMC4609797_02
Right eye before therapy.
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fig3
BCVA was 20/32 in right eye and 20/20 in left eye; slit-lamp examination showed wrinkling of the conjunctiva and keratinization in both eyes and sterile and peripheral ulcer in right eye (Figures 3 and 4).
Left eye before therapy.
CRIOPM2015-181267.004.jpg
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fig4
BCVA was 20/32 in right eye and 20/20 in left eye; slit-lamp examination showed wrinkling of the conjunctiva and keratinization in both eyes and sterile and peripheral ulcer in right eye (Figures 3 and 4).
Right eye after therapy.
CRIOPM2015-181267.005.jpg
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fig5
The conjunctiva and the cornea improved and, after 7-8 weeks, the cornea ulcer in right eye and the conjunctiva keratinization disappeared and a complete resolution of clinical manifestations was observed (Figures 5 and 6).
Left eye after therapy.
CRIOPM2015-181267.006.jpg
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fig6
The conjunctiva and the cornea improved and, after 7-8 weeks, the cornea ulcer in right eye and the conjunctiva keratinization disappeared and a complete resolution of clinical manifestations was observed (Figures 5 and 6).
PMC4609797_03
Right eye before therapy.
CRIOPM2015-181267.007.jpg
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fig7
At slit-lamp examination the patient presented keratinization of the conjunctiva and shortening of the lower conjunctival fornix in both eyes, partial corneal keratinization in the left eye (Figures 7(a), 7(b), and 8), and glaucomatous optic neuropathy in both eyes.
Right eye after therapy.
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fig9
The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.
Left eye after 3 weeks of therapy.
CRIOPM2015-181267.010.jpg
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fig10
The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.
Left eye after 8 weeks of therapy.
CRIOPM2015-181267.011.jpg
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fig11
The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.