PMC7251033_01
The patient's lymphoma chemotherapy timeline. Abbreviations: Ara-C, cytarabine; CDI, Clostridiumdifficile infection; CTX, cyclophosphamide; DXM, dexamethasone; IFO, ifosfamide; MTX, methotrexate; NHL, Non-Hodgkin's lymphoma; R, rituximab; VCR, vincristine; VP 16, etoposide. V-AA-RBB-RCC was the chemotherapy regimen combination used to treat the patient. V regimen: prednisone + CTX; AA regimen: DXM + IFO + VCR + Ara-C + MTX +VP 16; RBB regimen: R + DXM + CTX + VCR + MTX + Adriamycin; RCC regimen: R + DXM + vindesine + Ara-C +VP 16.
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F1
Figure 1. Following the final chemotherapy session 10 days before admission, she had been in a period of post-chemotherapy myelosuppression, during which she developed a severe infection.
(A) Jelly-like stool from the patient before treatment; (B) Stool from the patient 3 days after the initiation of treatment; (C) Normal stool from the patient after 10 days of treatment.
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F2
Subsequently, she developed diarrhea with jelly-like stools (Figure 2), abdominal distension, nausea, vomiting, and shortness of breath.
Computed tomography scan of the chest and abdomen showing multiple consolidations in both lung fields: (A) Pleural effusion and atelectasis bilaterally; (B) Massive ascites.
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F3
C. difficile culture using ChromID and C. difficile agar (CDIF) (bioMerieux, Marcy L'Etoile, France). Chest and abdominal computed tomography showed lung consolidations, pleural effusion, bilateral atelectasis, and massive ascites (Figure 3).