PMC7453141_01
Slit-lamp examination; nasal limbal gelatinous mass with inferior corneal infiltration
OC-10-30-g-001.jpg
PMC7453141_01_OC-10-30-g-001.jpg
F1
Slit-lamp examination showed a nasal limbal gelatinous mass with inferior corneal infiltration and cataract (Figure 1 (Fig. 1)).
CIN was confirmed by histopathological study with free margins; normal conjunctival epithelium at the top of the biopsy and dysplastic cells at the bottom in image 10x; dysplastic epithelium with high mitosis index in image 20x
OC-10-30-g-002.jpg
PMC7453141_01_OC-10-30-g-002.jpg
F2
An excisional biopsy was performed: A CIN with free margins was confirmed by the histopathological study (Figure 2 (Fig. 2)).
A) One month later, the lesion had decreased. B) At the third month, CIN had disappeared.
OC-10-30-g-003.jpg
PMC7453141_01_OC-10-30-g-003.jpg
F3
One month later, the lesion decreased in size (Figure 3A (Fig. 3)), and topical treatment was reduced to 1 drop three times a day. At the third month, no evidence of CIN was observed (Figure 3B (Fig. 3)), and the patient has since remained free of disease.
PMC7453141_02
A) Slit-lamp examination: a gelatinous temporal conjunctival mass (7x10 mm) with dilated superficial vessels without corneal involvement is exposed. B) Abduction limitation in right eye.
OC-10-30-g-004.jpg
PMC7453141_02_OC-10-30-g-004.jpg
F4
Slit-lamp examination revealed a gelatinous temporal conjunctival mass (7 mm long, 10 mm wide) with dilated superficial vessels (Figure 4A (Fig. 4)). Ocular movements were affected in the form of abduction limitation in the right eye (Figure 4B (Fig. 4)).
Anatomopathological study: moderately differentiated squamous cell carcinoma was confirmed; tumour cells present in corion
OC-10-30-g-005.jpg
PMC7453141_02_OC-10-30-g-005.jpg
F5
An incisional biopsy was performed and a moderately differentiated SCC was confirmed (Figure 5 (Fig. 5)).
A) Magnetic Resonance Imaging showed lateral rectus muscle involvement. B) Anterior Segment - Optical Coherence Tomography (AS-OCT): a hyperreflective lesion involving conjunctival tissue and spread over corneal surface
OC-10-30-g-006.jpg
PMC7453141_02_OC-10-30-g-006.jpg
F6
Magnetic resonance imaging (MRI) showed malignant infiltration of the lateral rectus muscle (Figure 6A (Fig. 6)). Anterior segment optical coherence tomography (AS-OCT) displayed a hyperreflective lesion which involved the conjunctival tissue and spread over the corneal surface (Figure 6B).
Tumor progression involving ocular globe tissues and soft periorbital structures
OC-10-30-g-007.jpg
PMC7453141_02_OC-10-30-g-007.jpg
F7
After five months, the tumor had progressed and involved ocular globe tissues and soft periorbital structures (Figure 7 (Fig. 7)).