PMC6056926_01
Transverse T2 MRI section. The section shows well-defined complex lesion (arrow) with solid and cystic contents in the pelvis, extending on either side of the midline reaching to both sides of adnexa and measuring 13 x 9.4 x 8.1 cm. Ovaries are not seen separately from the lesion. Uterus shows mild deviation to the left side due to pressure effect from the mass. No obvious lymph nodes or signs of metastasis
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Fig1
Further chest/abdomen/pelvis CT and MRI (Fig. 1) confirmed the size and solid/ cystic nature of the mass and showed no metastatic lesions, and also deviation of uterus to the left side. Upon histopathologic examination, a papillary thyroid carcinoma was identified arising in SO tumor (11.0 cm in greatest dimension) of the left ovary (Figs. 1, 2a and b), and a small metastatic focus measuring 0.1 cm in the right ovary.
Low and High power hematoxylin and eosin-stained section. a Low power hematoxylin and eosin-stained section (4x) demonstrates thyroid follicles of papillary carcinoma arising in benign thyroid follicles of SO. b High power hematoxylin and eosin-stained section (60x) demonstrates papillary thyroid carcinoma with follicular pattern. Nuclear features including nuclear groves, clearing, overlapping and enlargement, consistent with papillary thyroid carcinoma arising in a SO
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Fig2
Microscopic examination revealed an 11.0 cm left ovarian papillary thyroid carcinoma arising in SO (Figs. 2 and 3), with metastatic papillary thyroid carcinoma to the right ovary. Upon histopathologic examination, a papillary thyroid carcinoma was identified arising in SO tumor (11.0 cm in greatest dimension) of the left ovary (Figs. 1, 2a and b), and a small metastatic focus measuring 0.1 cm in the right ovary.
Thyroglobulin immunohistochemical stain. Low power thyroglobulin immunohistochemical stained section (4x) highlights the thyroid tissue in a background of ovarian tissue with SO
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Fig3
Microscopic examination revealed an 11.0 cm left ovarian papillary thyroid carcinoma arising in SO (Figs. 2 and 3), with metastatic papillary thyroid carcinoma to the right ovary. Thyroglobulin immunohistochemical stained section highlighted the thyroid tissue in a background of ovarian tissue with SO, and confirmed the origin from thyroid tissue (Fig. 3).