PMC535895_01
A: Axial, coronal and sagittal 99mTc-HMPAO SPECT images of the brain obtained during a facial twitching episode show moderate to severe heterogeneous cerebral hypoperfusion with an apparent focus of increased radiotracer uptake near the midbrain. B: 99mTc-ECD SPECT image of the brain obtained two weeks after (A) during a period free from twitching shows resolution of the area of increased uptake. C: Computer-generated depiction of A-B overlayed onto a co-registered MRI shows the area of increased uptake to lie outside the brain. See [5] or  for image analysis and alignment methodology.
1471-2385-4-2-1.jpg
PMC535895_02_1471-2385-4-2-1.jpg
F1
MRI using a computerized medical image registration and visualization program, the area of increased radiotracer uptake was seen to be anterior to the brain, likely in the sphenoid sinus, consistent with sinusitis (Figure 1C). MRI showed prominent maxillary and sphenoidal sinus mucosal thickening also consistent with sinusitis.
PMC535895_02
A: Axial, coronal and sagittal 99mTc-HMPAO SPECT images of the brain obtained during a facial twitching episode show moderate to severe heterogeneous cerebral hypoperfusion with an apparent focus of increased radiotracer uptake near the midbrain. B: 99mTc-ECD SPECT image of the brain obtained two weeks after (A) during a period free from twitching shows resolution of the area of increased uptake. C: Computer-generated depiction of A-B overlayed onto a co-registered MRI shows the area of increased uptake to lie outside the brain. See [5] or  for image analysis and alignment methodology.
1471-2385-4-2-1.jpg
PMC535895_02_1471-2385-4-2-1.jpg
F1
MRI using a computerized medical image registration and visualization program, the area of increased radiotracer uptake was seen to be anterior to the brain, likely in the sphenoid sinus, consistent with sinusitis (Figure 1C). MRI showed prominent maxillary and sphenoidal sinus mucosal thickening also consistent with sinusitis.