PMC10235440_01
Pedigree, head circumference, growth curve, and brain resonance images (MRI) of the proband. (A) Pedigree of the proband's family; black-filled shapes represent the proband, and the unfilled shapes represent the unaffected family members. Males are represented by squares, females by circles. (B) The proband with small head circumference grew slowly and lagged markedly behind the referent range. (C) The MRI showed bilaterally widened lateral ventricles but without structural anomalies when the proband was 6 years old.
fnins-17-1174925-g0001.jpg
PMC10235440_02_fnins-17-1174925-g0001.jpg
F1
The head circumference grew slowly and lagged obviously behind the referent range (WHO multicentre growth reference study group,) in later years (Figure 1B). When she was 6 years old, cerebral magnetic resonance imaging (MRI) showed bilaterally widened lateral ventricles without structural anomalies (Figure 1C).
PMC10235440_02
Pedigree, head circumference, growth curve, and brain resonance images (MRI) of the proband. (A) Pedigree of the proband's family; black-filled shapes represent the proband, and the unfilled shapes represent the unaffected family members. Males are represented by squares, females by circles. (B) The proband with small head circumference grew slowly and lagged markedly behind the referent range. (C) The MRI showed bilaterally widened lateral ventricles but without structural anomalies when the proband was 6 years old.
fnins-17-1174925-g0001.jpg
PMC10235440_02_fnins-17-1174925-g0001.jpg
F1
The head circumference grew slowly and lagged obviously behind the referent range (WHO multicentre growth reference study group,) in later years (Figure 1B). When she was 6 years old, cerebral magnetic resonance imaging (MRI) showed bilaterally widened lateral ventricles without structural anomalies (Figure 1C).