PMC3964157_01
The pathological images of primary breast cancer and the colonic mass.. Notes: (A) Mastectomy specimen obtained in 2001, showing lobular infiltrating carcinoma, are similar to infiltrating ductal carcinoma (hematoxylin and eosin stain, x100). (B) Right-colectomy specimen obtained in 2011, showing poorly differentiated ductal adenocarcinoma. Tumor emboli can be found in some lymph vessels (hematoxylin and eosin stain, x100).
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Histopathological examination suggested lobular infiltrating carcinoma and some of the signet ring cell carcinoma (Figure 1A). Histopathological examination showed poorly differentiated adenocarcinoma that had infiltrated into all the layers of colonic wall from the serosa, and cancer emboli were found in colonic lymph vessels (Figure 1B).
Abdominal computed tomography scan demonstrates an obvious thickened ascending colon and a soft-tissue mass (arrow) measuring 7.6 x 5.9 cm with a 31 Hounsfield unit (HU) computed tomography value.
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The enhanced computed tomography (CT) scan, after admission, also showed a 5.0 x 4.9 cm, low-density, oval, and sub-lobe opacity mass, which could be ring-enhanced in the right lobe of the liver, and a 7.6 x 5.9 cm soft tissue mass with density in the luminal wall of the ascending colon (Figure 2).
Immunohistochemistry scan of right-colectomy specimen.. Notes: (A) ER (+), x200; (B) CK7 (+), x200; (C) CK20 (+), x200; (D) GCDFP-15 (+), x200; (E) E-cadherin (+), x200.. Abbreviations: ER, estrogen receptor; CK7, cytokeratin 7; CK20, cytokeratin 20; GCDFP-15, gross cystic disease fluid Protein-15.
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Immunohistochemical stains showed tumor cells CK7 (+), E-cadherin (+), 34betaE12 (-), ER (+), GCDFP-15 (+), CK19 (+), CK20 (+), and liver cell (-) (Figure 3).