PMC7700994_01
Upper endoscopy showing swollen, granular and hyperemic mucosae with multiple polyploid formations (A), which were pearly and friable and occasionally presented superficial erosions (B).
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Endoscopy showed multiple pearly and friable gastric polyploid formations with superficial erosions and active blood oozing (Fig. 1).
Abdominal computed tomography presenting diffuse gastric mucosa enhancement with no signs of extramural extension or abdominal lymphomegalies. The stomach appears bulky and filled with protruding luminal content from the mucosae (A, axial view; B, coronal view).
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Abdominal computed tomography presented diffuse gastric mucosa enhancement with no signs of extramural extension or abdominal lymphomegalies (Fig. 2).
Resected stomach with regular external aspect (A). Specimen cut along the greater curvature, revealing important and diffuse enlargement of gastric folds, with friable polypoid formations of varying sizes and deposition of thick mucus in some areas of the mucous surface (B). Closer view of the polypoid formations (C).
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On gross examination, the surgical specimen showed the mucosa hyperemic and swollen, with prominent gastric folds and multiple friable polypoid formations in the entire stomach (Fig. 3).
Low power view of gastric mucosa with marked elongation and tortuosity of foveolae and disappearance of oxyntic glands. Submucosa has no glands at all (A). A closer view of mucous cell (foveolar) hyperplasia (B). Polypoid lesions had hyperplastic foveolae that are superficially dilated (C).
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Histopathological analysis revealed diffuse and marked hyperplastic elongation of gastric foveolas associated with disappearance of oxyntic glands, compatible with MD (Fig. 4).