PMC7771487_01
(a) Bone marrow aspirate smear shows aggregates of plasma cells showing eccentrically placed nucleus and cytoplasmic perinuclear hof (MGG stain, x400). (b) A giant binucleate myeloma cell showing coarse nuclear chromatin and prominent nucleoli. A mature plasma cell is seen in the background (MGG stain, x400). (c) Bone marrow biopsy shows increased plasma cells, seen as singly scattered cells (H and E, x400). (d) Serum electrophoresis shows a prominent M band in the gamma globulin region (arrowhead).
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F2
Bone marrow (BM) aspiration and trephine biopsy showed the presence of 17% plasma cells [Figure 2a-c]. Plasma protein electrophoresis revealed a prominent "M band" in the gamma globulin region [Figure 2d].