PMC6437325_01
Shorthair mixed-breed cat with kernicterus. Brain with marked yellowish pigmentation in the cortex of the cerebellar vermis and mild in the lateral regions of the cerebellar hemispheres
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Grossly, the cortex of the cerebellar vermis, the lateral regions of the cerebellar hemispheres and the optic chiasma had markedly yellow areas, which extended into the parenchyma, predominantly in gray matter (Figures 1 and 2).
Shorthair mixed-breed cat with kernicterus. Serial sections of cerebellum fixed in 10% buffered formalin. On the cut surface, the cerebellar vermis and the cerebellar hemispheres are yellow-to-greenish in appearance
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Grossly, the cortex of the cerebellar vermis, the lateral regions of the cerebellar hemispheres and the optic chiasma had markedly yellow areas, which extended into the parenchyma, predominantly in gray matter (Figures 1 and 2).
Liver of a shorthair mixed-breed cat with kernicterus. Ventral view of the liver with absence of gall bladder and a nodule measuring 2.0 cm (arrow), diagnosed as cholangioma
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It extended across the visceral surface of the left medial lobe (Figure 3).
Cerebellum of a shorthair mixed-breed cat. Cerebellar Purkinje neurons containing intracytoplasmic orange-to-brownish pigment are seen. Hematoxylin and eosin (x 400)
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The cytoplasm of some Purkinje layer neurons contained a moderate amount of granular and orange-to-brownish pigment (Figure 4).