PMC5733994_01
Images showing left adrenal adenoma measuring 2.9 x 1.9 x 2.5 cm (shown in circles).
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A follow-up scan revealed a stable benign left adrenal adenoma (2.9 x 1.9 x 2.5 cm) measuring 14 Hounsfield units on noncontrast CT (Figure 1).
Change in blood pressure over time after initiating mifepristone treatment.  *Alternating daily doses of 600 and 900 mg.
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After 4 weeks, her antihypertensive medication (amlodipine/olmesartan medoxomil 10/20 mg) was discontinued and her blood pressure remained stable (Figure 2).
Change in liver enzymes over time after initiating mifepristone treatment. ALT, alanine transaminase; AST, aspartate transaminase; ULN, upper limit of normal.
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During the course of mifepristone treatment, she lost 16 lbs and marked improvement in her liver enzymes was noted, with complete normalization by week 20 (Figure 3).
Change in ACTH over time after initiating mifepristone treatment. ACTH, adrenocorticotropic hormone; LLN, lower limit of normal.
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During the 34-week course of medical therapy with mifepristone, the patient's hypothalamic-pituitary-adrenal (HPA) axis recovered, as indicated by increases in ACTH levels from undetectable at baseline and week 16 to 2.4 pmol/L at week 24 (Figure 4).