PMC5933027_01
Endoscopic and histologic appearance of gastrointestinal metaplasia in case 1. (a) shows the appearance of a prepyloric nodule with an erosion located on the lesser curvature of the antrum. A cold forceps biopsy was taken from a region adjacent to the erosion (arrow). (b) shows a low power and (c) a high power histopathology image of the prepyloric nodule. The lamina propria is distended by a chronic inflammatory cell infiltrate consisting of lymphocytes and plasma cells. Numerous mucin producing cells, characteristic of intestinal epithelium, are identified. The features are those of chronic gastritis with intestinal metaplasia of the complete type.
CRIGM2018-5930415.001.jpg
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fig1
She underwent esophagogastroduodenoscopy (EGD), which revealed a 4 mm prepyloric nodule (see Figure 1(a)). HP was negative. Hematoxylin and eosin-stained sections on the prepyloric nodule biopsy showed antral-type gastric mucosa (see Figures 1(b) and 1(c)).
PMC5933027_02
Endoscopic and histologic appearance of gastrointestinal metaplasia in case 2. (a) shows the appearance of a prepyloric nodule with an erosion located on the lesser curvature of the antrum. A cold forceps biopsy was taken from a region adjacent to the erosion (arrow). (b) shows a low power image and (c) shows a high power histopathology image of the prepyloric nodule in case 2. The lamina propria is distended by a chronic inflammatory cell infiltrate, irregular columnar cells filled with mucin, and an absence of brush border is noted, signifying an incomplete type.
CRIGM2018-5930415.002.jpg
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fig2
The EGD showed a prepyloric nodule (Figure 2(a)) and bile-lake. Histological examination showed incomplete intestinal gastric metaplasia with irregular mucin droplets and an absent brush border (see Figures 2(b) and 2(c)).