PMC6885569_01
(A-C) Computed tomography angiography of intra-extracranial vessels performed on 12 May 2018: dissection at the passage between the extra- and intracranial part of the right internal carotid artery (white arrows). (D) High-resolution enhanced magnetic resonance imaging for cerebral artery plaques performed on 5 June 2018: a semicircular-shaped enlargement of the carotid wall with a hyperintense signal on the right suggested intramural hematoma but partial internal carotid recanalization (white arrow).
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Computed tomography angiography (CTA) of intra-extracranial vessels showed ICAD on the right side (Figure 1A-C). One week after antiplatelet treatment, a high-resolution enhanced MRI for cerebral artery plaques was performed, which suggested intramural hematoma but partial internal carotid recanalization compared to the previous CTA (Figure 1D).
(A) (a, b) Abdominal computed tomography angiogram (CTA) performed on 19 July 2018: partial infarction of right kidney (red arrow in a) and spleen (red arrow in b); (c, d) three-dimensional coronal reconstruction from CTA: dissection (red arrows) and small pseudoaneurysms (blue arrows) of right renal artery and splenic artery. (B) The upper chromatogram in each frame represents the reference sequence, and the lower one depicts the mutant sequence (c.799-1G>A within COL3A1) of the patient.
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An abdominal computed tomography angiogram (CTA) demonstrated dissection and small pseudoaneurysms of the right renal artery and splenic artery, in addition to partial infarction of the right kidney and spleen (Figure 2A). We found a novel splicing variant c.799-1G>A within COL3A1 (Figure 2B).