PMC6197149_01
(A-B): Two 14-s fragments of the patients' electroencephalograms showing the patterns before and after activation of the VNS.. Fragment (A) shows an electroencephalographic-pattern status epilepticus. Fragment (B) is from the patients' electroencephalogram after VNS activation showing marked slowing of background activity and few epileptiform discharges in the right temporal region.
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Interestingly, switching off the VNS resulted in seizure recurrence within 1 h, followed three days later by a non-convulsive status epilepticus which was refractory to intravenous midazolam and phenytoin treatment (Fig. 1A).