PMC3175412_01
The tumor shows a pedunculated large mass arising from the labia minora with a subtle stalk.
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fig1
Clinical examination showed a pedunculated bilobulated neoformation of ten centimeters in diameter of tense elastic consistency, at the level of the left labia minora (Figure 1).
(a) Photomicrograph (hematoxylin-eosin, original magnification x2) showing pedunculated lesion covered with skin. Note the proliferation of mesenchymal cells in richly vascularized fibrous stroma. (b) Photomicrograph (hematoxylin-eosin, original magnification x10) showing a mixture of hypercellular and hypocellular edematous areas with abundant small- to medium-sized vessels.
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fig2
Microscopically, the mass consisted of fibroconnective tissue with abundant vessels of various wall thickness (Figures 2(a) and 2(b)).
(a) Photomicrograph (immunohistochemical staining for desmin, original magnification x10) showing desmin positivity for mesenchymal proliferation. (b) Photomicrograph (immunohistochemical staining for estrogen receptors, original magnification x10) showing positivity of stromal elements for estrogen receptors.
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fig3
In immunohistochemistry, tumor cells were strongly positive for desmin and estrogen receptors (Figures 3(a) and 3(b)) and negative for alpha-smooth muscle actin, S-100 protein, cytokeratin, and CD34.