PMC2945663_01
Case 1. Pigmented lesion on the anterior aspect of the forearm.
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A 43-year-old woman with type IV skin type presented with a 0.8 x 1.6 cm pigmented lesion on the anterior aspect of the forearm (Figure 1).
Case 1. H&E shows pBD with parakeratosis and marked acanthosis consisting in atypical keratinocytes on all levels of the epidermis, dilated capillary vessels, and grouped melanophages only in the papillary dermis.
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H&E (Figure 2) showed parakeratosis and marked acanthosis consisting of a disarray of atypical keratinocytes on all levels of the epidermis.
PMC2945663_02
Case 2. Pigmented lesion on the left buttock and intergluteal fold.
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A 52-year-old woman with type III skin type consulted for a long-standing pigmented lesion on the left buttock and intergluteal fold (Figure 3).
Case 2. H&E shows pBD with marked hyperkeratosis, parakeratosis and acanthosis consisting of atypical keratinocytes on all levels of the epidermis. Dilated capillary vessels and grouped melanophages can be seen in the papillary dermis.
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H&E (Figure 4) showed marked hyperkeratosis and parakeratosis.
Dermoscopy in Case 1 shows central structureless brown and blue-gray pigmentation with keratosis, irregular peripheral pigmented streaks and brown regular globules in a linear arrangement. On the lower two thirds, light brown regular globules in linear and clustered arrangement, patches of clustered glomerular vessels, and a structureless hypopigmented central area.
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On the lower two thirds, there were light brown regular globules in linear and clustered arrangement, patches of clustered glomerular vessels, and a structureless hypopigmented central area (Figures 5, 6 and 7).
Case 1. Closeup view of upper third of the lesion with peripheral streaks, central brown and blue-gray pigmentation with keratosis and brown globules in a linear arrangement.
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On the lower two thirds, there were light brown regular globules in linear and clustered arrangement, patches of clustered glomerular vessels, and a structureless hypopigmented central area (Figures 5, 6 and 7).
Case 1. Closeup view of lower third of the lesion with patches of pigment globules and glomerular vessels in clustered and linear arrangement.
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On the lower two thirds, there were light brown regular globules in linear and clustered arrangement, patches of clustered glomerular vessels, and a structureless hypopigmented central area (Figures 5, 6 and 7).
Dermoscopy in Case 2 shows structureless brown and blue-gray peripheral pigmentation with keratosis, patches of brown regular globules in clustered a linear arrangement, clusters of glomerular vessels in a linear arrangement, keratin globules ("cotton candy" keratosis) scattered throughout the lesion, as well as a linear keratinous rim.
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Case 2. Closeup view of clusters of regular pigment globules and glomerular vessels in a linear arrangement. Central area shows brown and blue-gray structureless areas and keratosis.
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Case 2. Closeup view of "cotton candy" keratosis, keratinous rim and peripheral brown globules in linear arrangement.
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