PMC9479566_01
Magnetic resonance imaging brain demonstrating a large, 56 x 40 mm isolated lesion and presence of midline shift.
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F1
MRI demonstrated a 4.4 x 2.4 x 4.5 cm right basal ganglia lesion with extension into midbrain, peripheral enhancement with extensive surrounding edema, and 7 mm midline shift [Figure 1].
High-magnification image showing a brain biopsy with histiocyte-rich inflammatory infiltrate involving partially necrotic brain parenchyma.
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F2
Pathology was consistent with a histiocyte predominant neuroinflammatory process [Figure 2].
This toxoplasmosis immunostain demonstrates granular nuclear staining consistent with toxoplasma tachyzoite forms without tissue cysts.
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F3
Polymerase chain reaction analysis of the mass was positive for toxoplasmosis gondii [Figure 3].