PMC9583192_01
In the neonatal period, three-dimensional reconstruction of time-of-flight
magnetic resonance angiography of the head demonstrates a large, ruptured
aneurysm involving the inferior division of the M2 and M3 segments of the
left middle cerebral artery (a) and contrast-enhanced T1 axial brain
magnetic resonance imaging (b) demonstrates the aneurysm with surrounding
subarachnoid hemorrhage.
10.1177_2329048X221134600-fig1.jpg
PMC9583192_01_10.1177_2329048X221134600-fig1.jpg
fig1-2329048X221134600
At 29 days of life, he experienced progressive encephalopathy secondary to subarachnoid hemorrhage from a ruptured aneurysm located between the inferior branch of the M2 division of the left middle cerebral artery as well as the M3 division coursing along the frontal operculum along the sylvian fissure, as demonstrated on brain magnetic resonance imaging (Figure 1).
Coarse facial features demonstrated in our case of a male patient with a
variant to ANKRD-17.
10.1177_2329048X221134600-fig2.jpg
PMC9583192_01_10.1177_2329048X221134600-fig2.jpg
fig2-2329048X221134600
At 4 years of age, the patient has clinical characteristics of nonverbal intellectual disability, coarse facial features, ride sided hemiplegia, dysphagia, right sided hemianopsia, and drug-resistant multifocal epilepsy (Figure 2).