PMC3238497_01
(a) Initial EEG demonstrating slow wave activity inconclusive for status epilepticus, (b) periodic sharp wave complexes demonstrated on EEG.
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EEG (Figure 1(a)) showed general slowing with some sharpened slow waves, sometimes followed by periods of suppressed EEG activity. At day 43 after initial presentation repeat EEG now showed periodic sharp waves followed by suppression, characteristic of CJD (Figure 1(b)).
MRI scan demonstrating: (a) high signal in the caudate nucleus and (b) cortical ribboning.
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Repeat MRI revealed high signal in the caudate and basal ganglia, and ribbon-like cortical high signal change on the FLAIR sequence, also classic characteristics of CJD (Figure 2).
Spongiform encephalopathy (H&E stain).
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Neuronal loss and amyloid plaques were not mentioned in the report (Figure 3).