PMC6535691_01
Immunohistochemical staining of the resected tissue (100x magnification). (a) Epithelial cells were very strongly positive for cytokeratin-7 (CK7). (b) Nuclear P63 staining in the myoepithelial component confirmed the differentiation of the myoepithelium. (c) Strong nuclear S-100 staining confirms cell proliferation in the myoepithelial component of the malignant adenomyoepithelioma. (d) Positive smooth muscle actin staining in myoepithelial cells.
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Estrogen receptor and progesteron receptor detected negative, and c-erb2 shown weakly positive (1+). (Fig. 1, Fig. 2).