PMC5474534_01
Abdominopelvic CT-scan of patient. (a) Axial view showing bilateral hydronephrosis and nonuniform decreased cortex; (b) horizontal view showing multiple filling defects in bladder.
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Computed tomography (CT) imaging with and without intravenous contrast administration demonstrated bilateral hydronephrosis which was dominant in the left side; nonuniform decrease in the cortex of both kidneys and multiple filling defects were present in the bladder lumen without distant metastasis (Figure 1).
(a and b) Hematoxylin and Eosin stain: tumor was mainly composed of mucin lakes containing cords and nests of the tumor cells and some lakes bearing only signet-ring cells. Original magnification: x200 in (a) and x400 in (b).
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Microscopically, the bladder wall was infiltrated into deep muscularis propria (outer half) by a necrotic neoplasm composed of lakes of mucins containing floating nests or cords of epithelioid cells and many signet-ring cells (Figures 2(a) and 2(b)).