PMC6556266_01
Magnetic resonance imaging of the pelvis showed a well-circumscribed mass in the vulvar subcutaneous region.
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Magnetic resonance imaging (MRI) of the pelvis showed a well-circumscribed mass in the vulva (Figure 1).
On histopathological examination (x10;HE), the tumor was located in the subcutaneous region. There is an uninvolved segment between the tumor and overlying squamous epithelium. The boundary between the tumor and adjacent tissue was well demarcated.
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On histopathological examination (Figure 2), the boundary between tumor and adjacent tissue was clear.
Tumor cells were short and spindle-shaped, arranged in no overt architecture. The nuclei were oval, without prominent atypia. The intervening matrix was edematous and myxoid ((a); x400;HE). In some regions, fine collagen as well as dense collagen was detected ((b); x100;HE). The vast majority of blood vessels were small and thin-walled ((c); x100;HE). Some medium-sized blood vessels were also identified within the lesion ((d); x100;HE). There was no specific distribution pattern of the vascularity.
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Some medium-sized blood vessels were also identified within the lesion (Figure 3).
Immunohistochemically, positive nuclear staining for ER (a) and PgR(b) was observed. Tumor cells showed cytoplastic positivity for desmin (c) and alphaSMA (d). CD34 (e) and S100 protein were negative in all cells(f).
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The tumor cells were uniformly negative for S100 protein (Figure 4).