PMC6000835_01
Metastatic malignant melanoma in the left inguinal lymph node: (a) H&E at x40 and (b) H&E at x400. The tumor cells are positive for vimentin (c), S100 (d), and HMB-45 (e).
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The immunophenotype is consistent with malignant melanoma (Figure 1).
Abdominal CT scan at the time of diagnosis demonstrated matted paraaortic nodes.
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Computer tomography of the whole abdomen showed multiple enlarged lymph nodes throughout the abdominal and pelvic cavity up to 9.5 cm, along with compression of both iliac veins without an organ-specific lesion (Figure 2).
The following CT scan revealed a marked decrease in size of intra-abdominal lymph nodes.
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The CT scan at the first 3 months showed that the response was stable disease, but the following CT scan demonstrated a gradual decrease in size over time from August 2012 to November 2017 (Figure 3).