PMC4318038_01
Lesion on perineal area
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F1
Dermatological examination revealed approximately a 7 x 8 cm well-marginated, hypertrophic, and verrucous plaque in the perineal region. [Figure 1] At places grayish crusts with shallow erosions and a purulent discharge was seen. [Figure 2] There was no similar lesion anywhere else on the body.
Erosions and crusts over the plaque
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F2
Dermatological examination revealed approximately a 7 x 8 cm well-marginated, hypertrophic, and verrucous plaque in the perineal region. [Figure 1] At places grayish crusts with shallow erosions and a purulent discharge was seen. [Figure 2] There was no similar lesion anywhere else on the body.
Paget's cells in H and E stain x10
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F3
Inflammatory infiltrate with invasion of Paget's cells into the dermis at places was seen [Figure 3].
Paget's cells in PAS stain x40
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F4
Cells were positive for PAS lying singly and in clusters also seen infiltrating along the skin appendages [Figure 4].