PMC9946905_01
Bullae (on right forearm; top left), granulation tissues (on left ankle; top right), rashes (on back; bottom left), and several vesicles (bottom right).
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FIG1
On physical examination, several vesicles, bullae, rashes, and granulation tissues on the face, arms, trunk, legs, and ankles were documented (Figure 1).
Histopathological slide (haematoxylin and eosin stain) showing clefting and blister formation at the junction of dermis and epidermis.
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FIG2
The roof of the blister comprised a full-thickness epidermis (Figure 2).
Direct immunofluorescence mapping with fluorescence antisera against type IV collagen (localized on the basal lamina) indicates a positive linear immunofluorescence at the base of the blister (arrow).
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PMC9946905_01_cureus-0015-00000034117-i03.jpg
FIG3
This allocation of type IV collagen in the blister shows a junctional cleavage (Figure 3).