PMC9720243_01
Rowell Syndrome. A 43-year-old female presents with severe, photo-induced rash of 3 months duration. Hyperpigmented patches with serpiginous borders and erythematous plaques with central clearing are visible.
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Additionally, erythematous discrete plaques with central clearing, consistent with lupus erythematosus (LE), and hyperpigmented patches with serpiginous borders, consistent with postinflammatory pigment alteration, were present (Fig 1).
Rowell Syndrome. A 43-year-old female with a Past Medical History of systemic lupus erythematous was admitted for pain control and pulse dose steroids for treatment of RS following prednisone withdrawal. She was also being treated with hydroxychloroquine and mycophenolate mofetil prior to admission.
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Flares required 2 hospitalizations for pulse dose steroids and pain control (Fig 2).
Rowell Syndrome (RS). A 43-year-old female with known RS after 10 months of treatment with anifrolumab 300 mg infusion every 4 weeks.
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She tolerates it well and has had no skin flares while receiving monthly anifrolumab infusions, despite tapering her steroid to discontinuation within 2 weeks of beginning anifrolumab (Fig 3).