PMC3023681_01
Preoperative appearance of the patient. A 2 x 1 cm reddish mass with 3 x 2 cm brownish plaque-like cutaneous thickening.
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F1
On gross inspection and palpation, we noticed a 2 cm x 1 cm smooth mobile keloid-like reddish mass surrounded by a 3 cm x 2 cm brownish plaque-like cutaneous thickening in the medial lower quadrant, at the 7 o'clock position of her left breast (Figure 1).
Gross specimen. Outer surface of ill-defined gray rubbery mass.
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F2
Gross specimen. Cross section of the mass.
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F3
Microscopic examination. Several atypical cell with mitosis in the relatively blend spindle cells was noticed (H&E stain, x 400).
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F4
On histological examination, a storiform pattern of spindle cells infiltrating into subcutaneous tissue above the mammary gland was noticed (Figure 4, 5, 6).
Microscopic examination. There is characteristic infiltration of fibroblast between fat cells in subcutaneous tissue (H&E stain, x 200).
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F5
On histological examination, a storiform pattern of spindle cells infiltrating into subcutaneous tissue above the mammary gland was noticed (Figure 4, 5, 6).
Microscopic examination. Infiltrative border in dermis was observed (H&E stain, x 100).
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F6
On histological examination, a storiform pattern of spindle cells infiltrating into subcutaneous tissue above the mammary gland was noticed (Figure 4, 5, 6).
Immunohistochemical examination. Tumor stained positive for CD34.
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F7
On immunohistochemical examination, the lesion stained positive for CD34 (Figure 7) and locally positive for SMA, and negative for CD68 and S-100 protein (Figure 8).
Immunohistochemical examination. Tumor stained negative for S-100 protein.
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F8
On immunohistochemical examination, the lesion stained positive for CD34 (Figure 7) and locally positive for SMA, and negative for CD68 and S-100 protein (Figure 8).