PMC4531979_01
A. Multiple geographic variable-sized shallow ulcers with discrete margin in the colon.. B. Deep clear ulcer with whitish plaque on the ulcer base and somewhat nodular margin.
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Colonoscopy showed geographic ulcerations along the entire colon, especially rectum and terminal ileum(Fig. 1).
A. Diffuse infiltration of monotonous small atypical lymphocytes in the colonic mucosa (H&E, x200).. B. Immunostaining for CD45RO showing strong positivity in the infiltrating lymphocyte(x400).
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Histologic examination of the colon showed diffuse infiltration of monotonous small atypical lymphocytes in the laminar propria of the colon(Fig. 2A). However, they were positive for CD45RO(Fig. 2B) and CD3, negative for CD20.