PMC4408673_01
(a) The follicular cells show columnar cell change with abundant finely granular cytoplasm. (b, e and f) Nuclear overlapping and pleomorphism. (b and e) Bi- and multinucleation. (c) Phagocytosis of polymorphs by giant cell is also appreciable. (c and d) Many multinucleated giant cells. Coarsening of chromatin (e-i) and prominent intranuclear inclusions well appreciated with MGG (e and f) as well as Pap (g-i). (a,d,g-i: Pap, x400); (b,c,e,f: MGG, x400)
JCytol-32-25-g001.jpg
PMC4408673_01_JCytol-32-25-g001.jpg
F1
Thick colloid globules were present with many multinucleated giant cells [Figure 1c and d] and foci of microcalcifications. The follicular cells showed columnar cell changes with abundant finely granular cytoplasm [Figure 1a], nuclear overlapping and pleomorphism [Figure 1b, e and f], bi- and multinucleation [Figure 1b and e], coarsening of chromatin [Figure 1e-i] and prominent intranuclear inclusions well appreciable with May Grunwald Giemsa (MGG)- [Figure 1e and f] as well as Papanicolaou (Pap) [Figure 1g-i]-stained smears, but no nuclear clearing or grooves.