PMC4691417_01
SAVI. Cartilage destruction and scarring on the left helix at the site of previous ulceration.
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F1
There was partial loss of both helices with atrophic scarring (Fig 1).
A and B, SAVI. Hyperkeratotic scale and multiple erosions, ulcerations and digit amputations.
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F2
The distal extremities were remarkable for amputation of several digits on the hands and feet with overlying scale, atrophy, and a violaceous hue (Fig 2).
Histopathology of hyperkeratotic plaques on knees in SAVI syndrome. A, Dilated vessels in papillary dermis with large thrombi. B, Mild perivascular lymphocytic infiltrate with rare neutrophils and mild karyorrhexis. (A and B, Hematoxylin-eosin stain; original magnifications: A, x40; B, x400.)
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F3
A mild perivascular lymphocytic infiltrate with rare neutrophils and mild karyorrhexis was observed in the dermis (Fig 3).