PMC4238172_01
The graph depicts the rise and fall of transaminases and bilirubin from the time of 8 weeks after presentation. The table below the graph shows the numerical values. (Y-axis on left side is in IU scale and Y axis on right side is in mg/dL scale).
CRIHEP2013-965092.001.jpg
PMC4238172_01_CRIHEP2013-965092.001.jpg
fig1
She was incidentally found to have abnormal liver tests in the form of elevated aminotransferases and hyperbilirubinemia (Figure 1). AST was down to 668 from 893 and ALT was down to 1144 from 1247. After 8 weeks the liver enzymes had completely normalized (Figure 1).
Low magnification of the liver biopsy showing histologic features of a panacinar hepatitis with moderate mixed portal and lobular inflammation ((a) Hematoxylin and Eosin, 100x). Higher magnification of the mixed portal inflammation with lymphocytes, plasma cells, and eosinophils with foci of lobular injury with an acidophil body (arrow) ((b) Hematoxylin and Eosin, 200x).
CRIHEP2013-965092.002.jpg
PMC4238172_01_CRIHEP2013-965092.002.jpg
fig2
A liver biopsy (Figures 2(a) and 2(b)) was performed which showed histologic features of a panacinar hepatitis, with expansion of the portal tracts by a mixed chronic inflammatory infiltrate composed of lymphocytes, eosinophils, and plasma cells.