PMC6433933_01
Serial MRI Brain sequences for hospital day 1, 8, and 21. On hospital day 1, there is abnormal hyperintense T2 FLAIR signal in the bilateral deep gray nuclei without associated restricted diffusion. On hospital day 8, there is progressively increasing abnormal T2 signal in the deep gray nuclei as well as restricted diffusion within the areas of abnormal T2 signal. There are no abnormalities on T1 pre and post contrast sequences. On hospital day 21, there is evolving T2 hyperintense signal in the bilateral deep gray nuclei with similar degree of restricted diffusion. There is now an abnormal T1 hyperintense signal in the deep gray nuclei without contrast enhancement, suggestive of developing gliosis.
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F1
Brain without contrast (hospital day 1) showed abnormally increased T2 FLAIR signal in the deep gray nuclei bilaterally, most prominent in the striatum (Figure 1). Blood cultures were negative throughout her hospitalization.