PMC6481119_01
Kidney Biopsy. Electron microscopy identifying a split lamina densa (top left). Light microscopy demonstrating significant tubular atrophy and interstitial fibrosis (top right). Immunofluorescence highlighting absent staining for the a5 chain of type 5 collagen in the patient and no immune deposits (bottom row).
CRIN2019-8720837.001.jpg
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fig1
Surprisingly, the electron microscopy revealed the characteristic features of Alport's syndrome (Figure 1).