PMC9282684_01
(a) Verrucous plaques seen on the scrotum. (b) Posttreatment (after 16 weeks of isotretinoin)
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F1
Nontender dark gray-to-black-colored coalescing verrucous plaques [Figure 1a] covering most of the anterior surface of the scrotum were seen and the same extended to the posterior and right lateral surfaces also. After 16 weeks of isotretinoin, all the lesions cleared well [Figure 1b], following which his dosage has been tapered to 10 mg/day and continued in the same dosage for another 16 weeks.
HPE x40 showing koilocytes in the upper epidermis
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F2
Biopsy was taken from the edge of the lesion which showed acanthosis and koilocytes in the epidermis [Figure 2].