PMC8267787_01
A Chinese family with KLF1 compound heterozygote mutation causing transfusion-dependent hemolytic anemia. (A) The pedigree, hematological parameters, and genotype data of family members. (B) Sanger sequencing of the KLF1 gene shows the p.Ala298Pro and p.Gly176Argfs*179 mutations. Amino acids are indicated above each chromatogram, with base pair and amino acid changes highlighted in red.
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F1
The pedigree of this family is shown in Figure 1A).