PMC6955129_01
Esophagogastroduodenoscopy showing diffusely thick gastric folds were found in the gastric fundus and in the gastric body with characteristic sparing of antrum.
CRIGM2019-7927083.001.jpg
PMC6955129_01_CRIGM2019-7927083.001.jpg
fig1
This is shown in Figure 1.
(a) Gastric folds biopsy on low power magnification showing mucosal thickening with foveolar hyperplasia and cystic dilatation of the gland (H and E, magnification x2) consistent with Menetrier disease. (b) Another section of the gastric folds biopsy showing foveolar hyperplasia with excessive mucous spills on the luminal surface and a cystically dilated gland (H and E, magnification x100).
CRIGM2019-7927083.002.jpg
PMC6955129_01_CRIGM2019-7927083.002.jpg
fig2
The biopsied enlarged gastric folds revealed gastric fundic mucosa with foveolar hyperplasia, dilated fundic glands and chronic gastritis which is shown in Figure 2.
Endoscopic ultrasound showing wall thickening was seen in the body of the stomach. The thickening appeared to be primarily within the sub mucosa (Layer 3), >1 cm.
CRIGM2019-7927083.003.jpg
PMC6955129_01_CRIGM2019-7927083.003.jpg
fig3
The thickening appeared to be primarily within the submucosa (Layer 3) of the stomach (Figure 3).