PMC8458931_01
Location of ABCC8 mutations in the SUR1 protein (A) and KCNJ11 mutations in the Kir6.2 protein (B) identified in 27 Vietnamese patients with NDM. TMD, transmembrane domain.
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Eight KCNJ11 mutations identified in this study are located in the N- and C-terminal regions (Figure 1B), which form the ATP binding pocket of Kir6.2.
The glycemic control (A) and reduction of HbA1C levels (B) with switching from insulin to sulfonylurea therapy. SU, sulfonylurea.
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Excellent glycemic control was maintained after commencing SU therapy (Figure 2A), which is similar to other reports.