PMC3150772_01
Posterior lower limbs demonstrating segmental linear plaques of warty papules on a background of less prominent hyperkeratotic papules and plaques.
JSC2012-839561.001.jpg
PMC3150772_01_JSC2012-839561.001.jpg
fig1
These formed large linear plaques which were more prominent on the left half of the body and followed Blaschko lines (Figures 1 and 2).
Left lateral upper limb demonstrating diffuse hyperkeratotic papules and plaques.
JSC2012-839561.002.jpg
PMC3150772_01_JSC2012-839561.002.jpg
fig2
These formed large linear plaques which were more prominent on the left half of the body and followed Blaschko lines (Figures 1 and 2).
Left thumbnail demonstrating longitudinal erythronychia and distal nicking of the nail plate.
JSC2012-839561.003.jpg
PMC3150772_01_JSC2012-839561.003.jpg
fig3
Several fingernails demonstrated longitudinal erythronychia and distal nicking of the nail plate (Figure 3). 
Left popliteal fossa demonstrating a shiny telangiectatic papule within a linear collection of keratotic papules in the left popliteal fossa.
JSC2012-839561.004.jpg
PMC3150772_01_JSC2012-839561.004.jpg
fig4
An erythematous shiny telangiectatic papule measuring 7 mm in diameter was noted within a linear collection of papules in the left popliteal fossa (Figure 4).
Histopathology of papule in left popliteal fossa consistent with nodular basal cell carcinoma.
JSC2012-839561.005.jpg
PMC3150772_01_JSC2012-839561.005.jpg
fig5
A biopsy of the papule confirmed this to represent a nodular basal cell carcinoma (Figure 5) surrounded by characteristic suprabasal acantholysis and dyskeratosis seen in DD (Figures 6 and 7).
Histopathology demonstrating characteristic Darier's pathology of suprabasal acantholysis and dyskeratosis.
JSC2012-839561.006.jpg
PMC3150772_01_JSC2012-839561.006.jpg
fig6
A biopsy of the papule confirmed this to represent a nodular basal cell carcinoma (Figure 5) surrounded by characteristic suprabasal acantholysis and dyskeratosis seen in DD (Figures 6 and 7).
Histopathology demonstrating nodular basal cell carcinoma surrounded by characteristic suprabasal acantholysis and dyskeratosis seen in Darier's disease.
JSC2012-839561.007.jpg
PMC3150772_01_JSC2012-839561.007.jpg
fig7
A biopsy of the papule confirmed this to represent a nodular basal cell carcinoma (Figure 5) surrounded by characteristic suprabasal acantholysis and dyskeratosis seen in DD (Figures 6 and 7).