PMC6854842_01
The performance of Molecular Association Network (MAN)-High-Order Proximity preserved Embedding (HOPE) for predicting miRNA-disease associations. (A) five-fold cross-validation performance using behavior (network embedding) feature and attribute feature of nodes; (B) five-fold cross-validation performance using only attribute feature; (C) five-fold cross-validation performance using only behavior feature; (D) comparison of performance of attribute feature, behavior feature, and combined use for predicting miRNA-disease associations.
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Results of MAN-HOPE for predicting miRNA-disease associations are shown in  Table 4  and  Figure 7 . As shown in  Figure 7A , MAN-HOPE can achieve good performance with an accuracy of 85.89% and an AUC of 92.04%. The performances are shown in  Figures 7B-D .