PMC8020601_01
Rectal biopsy and abdominal computed tomography.. A. Rectal mucosa biopsy, hematoxylin-eosin staining, optical microscopy. Mucosal injury with inflammation and ulceration (black dashed arrow) and many cytomegalovirus inclusion bearing cells. Insert shows ballooned cells with cytomegalovirus inclusions at higher magnification (white arrows).. B. Rectal mucosa biopsy, immunohistochemistry with an anti-CMV antibody. Multiple cytomegalovirus infected cells in the ulcerated area (black arrows).. C. Iodinated contrast agent-enhanced abdominal computed tomography, coronal section. Rectal wall thickening with mucosal edema and peri-rectal fat infiltration: uncomplicated proctitis.
gr1.jpg
PMC8020601_01_gr1.jpg
fig0005
An abdominal iodinated contrast agent-enhanced CT revealed a circumferential thickening of the rectal wall, with peri-rectal fat infiltration and enhancement of rectal mucosa, consistent with uncomplicated proctitis (Fig. 1). Pathologic examination of the rectal biopsy (Fig. 1) revealed an ulcerated rectal mucosa and a cytopathogenic effect with ballooned cells ("owl's eye") and cytomegalovirus inclusions.