PMC4802522_01
Erythematous deep-seated papules were scattered over the patient's face, arms, chest, and hands. Note involvement of the eyelids and solitary pustules surmounting papules.
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Several lesions were erythematous papules with pustular centers (Fig 1).
Histopathologic features. A punch biopsy of the right forearm shows a dense diffuse superficial and deep infiltrate with an intraepidermal pustule and marked subepidermal edema, bordering on vesiculation, with leukocytoclasis evident in the edematous papillary dermis. (Original magnification: x200.)
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No microorganisms were identified via staining (Fite, Grocott's Methenamine Silver, Periodic acid-Schiff-diastase, Brown-Brenn, immunoperoxidase studies for herpes simplex virus I/II and varicella zoster virus; Fig 2).