PMC4408683_01
(a) Microscopy showing highly cellular tumor comprising of spindle cells arranged in a fascicular and herring bone pattern (H and E, x100). (b) Intra-operative squash smears showing monotonous population of short spindle cells arranged in fragments and single cells containing scant granular cytoplasm and coarse chromatin with comma shaped nuclei (MGG, x100)
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F1
Frequent mitotic figures along with small foci of calcification were seen [Figure 1b]. Histopathological examination of the soft tissue mass revealed a highly cellular tumor comprising of spindle cells arranged in a fascicular and herring bone pattern [Figure 1a].
Tumor cells showing bcl-2 positivity (IHC, x400)
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F2
On IHC the tumor cells were positive for bcl-2 [Figure 2], MIC-2 and EMA.