PMC6595665_01
(a) Transversal image of the CT scan showing a large, multilobulated, hepatic mass. (b) Ultrasonographic appearance of the liver tumour. (c) Sagittal image of the thorax and abdomen showing heterogeneous contrast enhancement of the liver
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CT of the head, thorax and abdomen revealed a 15 cm maximum diameter, multilobular cystic mass arising from the caudal left liver lobe (Figure 1).
(a) Micrograph of the hepatocellular carcinoma on the left, with normal congested hepatic parenchyma on the right. Haematoxylin and eosin, x 200. (b) Micrograph showing the negative immunostaining for insulin growth factor 2 (IGF-2). Inset: positive IGF-2 staining in the normal liver
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IGF-2 immunohistochemistry on sections from formalin-fixed, paraffin-embedded liver biopsies using an IGF-2 antibody (1:200; ab9574 [Abcam]), and feline colonic tissue as a positive control, revealed scattered positive staining in normal hepatocytes but not in neoplastic cells (Figure 2).