PMC5228690_01
(A) Pretreatment, an immunoglobin G monoclonal band containing a kappa light chain was visualized using immunoelectrophoresis (IEP) analysis. (B) Post-treatment, the monoclonal band had disappeared. Serum 1 refers to the patient's serum. IEP = immunoelectrophoresis.
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F1
Analysis using serum electrophoresis and immunoelectrophoresis (IEP) revealed a monoclonal band that was IgG with a kappa light chain (Fig. 1A). The patient achieved complete remission (CR) by the end of the 4 cycles of chemotherapy (Fig. 1B).
(A) There was an increased population of abnormal plasma cells with dysplastic features in the bone marrow (Wright staining x1000). (B) A CT-guided needle biopsy of the left lung sampled moderately-differentiated adenocarcinoma (H&E x600). (C) Pathological analysis of the T3 tissue found diffuse infiltration of plasma cells with unclear intranuclear findings and unevenly distributed nuclei (H&E x600). CT= computed tomography, H&E = hematoxylin and eosin staining.
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F2
Bone marrow (BM) aspirate had an increased population of abnormal, dysplastic plasma cells (23%) (Fig. 2A). T3 tissue. This plasmacytoma consisted of atypical plasma cells with irregular nuclei and cytoplasmic vacuolation, as assessed by haematoxylin and eosin (H&E) staining (Fig. 2C).
(A) Before treatment, CT-scans revealed a round mass with ground glass opacities in the lower left lobe of the lungs. (B) After surgery, the CT-scan displayed the shadow of the left lower lung wedge resection. CT= computed tomography.
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F3
Chest CT scan uncovered a round mass with ground glass opacities in the left lower lobe of the lungs (Fig. 3A). Ten days post-diagnosis, a left lower lobectomy, as well as hilar and mediastinal lymph node dissection, was performed using video-assisted thoracic surgery (VATS) (Fig. 3B).