PMC3564726_01
Destruction of the midface with swelling of surrounding facial tissues and lower part of the nose.
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F1
On admission to hospital he had a fever, headache, conjunctivitis, swelling of the eyelids and of the lower part of the nose, and destruction of the entire midface with indurated swelling of the surrounding tissues (Figure 1).
Coronal C.T: destruction of the medial walls of the maxillary sinuses and veiling of maxillary sinuses, ethmoidal sinus, frontal sinus and the nasal cavity.
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F2
Axial C.T: homogeneous soft tissue mass filling the anterior nasal cavity with bilateral obliteration of the maxillary sinuses, nasal cavity and the posterior nasal space. Note the destruction of the anterior portion of the face, including the nose.
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F3
NK/T cell lymphoma, nasal type. A: atypical lymphocytes arranged in a vaguely angiocentric pattern (H&E, original magnification X 40). B: atypical lymphocytes positive for CD56 (original magnification X 40).
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F4
The atypical lymphoid cells exhibited large nuclei, hyperchromatism, and some of them exhibited abnormal mitotic figures (Figure 4A). Immunophenotypically, the tumour cells were positive for CD3 and CD56 (Figure 4B), but negative for CD20.