PMC5917519_01
Clinical photographs showing swelling in the right submandibular region in a 16 year-old male patient (fornt)
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F1
The swelling measured approximately 4 cm x 2 cm on palpation which was soft and not fixed to underlying tissues [Figures 1 and 2].
Clinical photographs showing swelling in the right submandibular region in a 16 year-old male patient (side view)
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F2
The swelling measured approximately 4 cm x 2 cm on palpation which was soft and not fixed to underlying tissues [Figures 1 and 2].
Section of lymph node shows scattered reactive lymphoid follicles with prominent germinal centers (H&E, x10)
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F3
Sections taken from the submitted specimen stained with Haematoxylin and Eosin stain showed reactive lymph follicles, focal areas of monocytoid B cells along with many well-formed nonnecrotizing epithelioid granulomas in the paracortex, focally impinging in the germinal centers [Figures 3 and 4].
Focal areas of interfollicular expansion by epithelioid cell granulomas and large mononuclear cells (x40)
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F4
Sections taken from the submitted specimen stained with Haematoxylin and Eosin stain showed reactive lymph follicles, focal areas of monocytoid B cells along with many well-formed nonnecrotizing epithelioid granulomas in the paracortex, focally impinging in the germinal centers [Figures 3 and 4].
Predominantly mononuclear cells showing prominent nucleoli (x40)
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F5
Immunohistochemical staining shows CD30 positive for the large cells
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F6
Immunohistochemistry positive for Pax 5
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F7