PMC3369265_01
Summary of the changes in the IOP and treatments for the last uveitis attack of the left eye. The first day of the last uveitis attack was defined as week 0. A line graph with open circles demonstrates representative IOPs at each period. Anterior uveitis and elevated IOP were successfully treated after preoperative infliximab administration followed by trabeculotomy one week later. Inflammation in the anterior chamber is described. Oral administration of prednisolone, levofloxacin hydrate, and isoniazid are indicated by shading, and all other agents were topically administrated. Arrows indicate IOPs before and after intravenous administration of D-mannitol and acetazolamide. PSL = Oral prednisolone (mg/day); KP = keratic precipitates; i.v. = intravenous administration of D-mannitol (500 ml) and acetazolamide (500 mg) twice a day.
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F1
Four months later, this patient came to our department again because of elevated IOP (45-50 mm Hg) with inflammation in the anterior chamber (cells 2+, flare 2+, KP 2+) and the vitreous (cells +) of his left eye (fig. 1). Infliximab therapy (5 mg/kg) was intravenously administered at weeks 4 and 6 (fig. 1; week 0 was defined as the first day of the last uveitis attack). Third infliximab therapy was intravenously administered at week 10 (fig. 1) and every 8 weeks thereafter. A summary of changes in the left IOP and of treatments after the last uveitis attack are shown in figure 1.