PMC4214168_01
MRI brain on presentation.
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Magnetic resonance imaging of the brain (MRI) demonstrated infarction of the right parietooccipital region, left occipital polar region, and the right cerebellar hemisphere consistent with catastrophic antiphospholipid syndrome (Figure 1).
Kidney biopsy showing thrombotic microangiopathy.
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Renal biopsy was performed reporting evidence of both acute and chronic thrombotic microangiopathy involving both glomeruli and arteries/arterioles favoring diagnosis of antiphospholipid antibody syndrome (Figure 2).
MRI brain 5 months after presentation.
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MRI of the brain was repeated 5 months after presentation revealing no acute changes with evidence of chronic basal ganglia infarcts and extensive encephalomalacia (Figure 3).