PMC9583201_01
Cerebral MRI in coronal, sagittal and axial section showing a
superolateral extraconal tissular mass extending through the superior
orbital fissure and along the dura mater measuring 36.6 mm x
32.7 mm.
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The cerebral computed tomography (CT) and magnetic resonance imaging (MRI) showed a superolateral extraconal tissular mass extending through the superior orbital fissure and along the dura mater, measuring 36.6 mm x 32.7 mm (Figure 1).
(a) Langerhans cell histiocytosis showing intermediate-sized cells with
grooved, indented and lobed nuclei and pale eosinophilic cytoplasm
surrounded by large numbers of eosinophils (HEx400). Langerhans cell
histiocytosis with S100 (b) and CD1a (c) immunoreactivity on the
majority of cells (IHCx400).
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On immunohistochemistry, Langerhans cells express S100 and CD1a (Figure 2).
Orbital MRI revealing no abnormalities 9 months after diagnosis.
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On account of this CT-MRI discordance, we performed an Orbital MRI which revealed no abnormalities compared with the first one (Figure 3).