PMC8543013_01
Histology of the surgical specimen. (A) Calcitonin-positive medullary thyroid cancer is adjacent to normal thyroid tissue (immunohistochemistry, x10). (B) Solid nests of metastatic medullary thyroid cancer (arrows) in a lymph node (hematoxylin and eosin, x10).
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Tumor cells were positive for calcitonin, chromogranin-A, synaptophysin, and neural cell adhesion molecule (CD56) by immunohistochemistry ( Figure 1 ).