PMC8575692_01
CT images of bilateral chest. (A,B) are CT scan images taken on June 5, 2019, Scanning model: GE BrightSpeed, scanning parameters: slice thickness: 5 mm, gap: 5 mm. (A) Round ground glass opacity in the posterior segment of the left superior lobe apex, the boundary is clear, in the center, there is a dot-like translucent shadow. (B) Round ground glass opacity in the anterior basal segment of the right lower lobe, the edge is smooth and clear, it can be seen that vascular shadow naturally passes through. (C,D) are CT scan images taken on January 13, 2021, scanning model: United image uCT, scanning parameters: slice thickness: 5 mm, gap: 5 mm. The 2 ground glass opacities of the posterior segment of the left upper lobe apex (C) and the anterior basal segment of the right lower lobe (D) are roughly similar to that of the film taken on June 05 2019. (C) CT image of ground glass opacity in the posterior segment of the left superior lobe apex. (D) CT image of ground glass opacity in the anterior basal segment of the right lower lobe.
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F1
After admission, he underwent a chest CT examination, which showed that there was no significant change in the GGOs when compared with imaging conducted in 2019 (see Figure 1).
The pathological images of two GGOs show that the heteromorphic cells are arranged in the form of acini, the cells are dense, the nucleus is hyperchromatic, the cytoplasm is abundant and eosinophilic, peripheral fibrous tissue and lymphocyte proliferate. (A) Lesions in the posterior segment of the left upper lobe apex, HE x200. (B) Lesions in the posterior segment of the left upper lobe apex, HE x400. (C) Lesions in anterior basal segment of right lower lobe, HE x200. (D) Lesions in anterior basal segment of right lower lobe, HE x400.
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F2
No tumor thrombus was found in the vessel, and no cancer was found in the nerve bundle, but the lymph node tissue exhibited chronic inflammatory changes (group 10 lymph nodes and group 5/6 lymph nodes were sent for testing; see Figure 2).
Immunohistochemistry [TTF-1 (+), Napsin A (+)]. (A) TTF-1 x100. (B) TTF-1 x400. (A,B) Positive staining of TTF-1 in the nuclei of lung adenocarcinoma. (C) NapsinA x100. (D) NapsinA x400. (C,D) Positive staining of NapsinA in the cytoplasm of lung adenocarcinoma.
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F3
A (+), thyroid transcription factor-1 (+), cytokeratin (CK) 5/6 (-), bronchial myoepithelium (P40 +), CK7 (+), EMA (+), vimentin (+), P63 (non-specific +; see Figure 3). A follow up on May 24, 2021 showed that the child had recovered well without any further discomfort.