PMC7539115_01
Timeline.
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F1
An 83-year-old male presented in March 2016 with progressive shortness of breath (Figure 1).
(A) Pre-treatment MRI, coronal, and axial views, (B) post-SRS and immunotherapy MRI, (C) pre-treatment CT, coronal view, and (D) post-treatment CT.
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F2
Imaging showed progression of metastatic disease with bilateral increase in size of pulmonary nodules, mediastinal lymphadenopathy, an additional osseous lesion in the pelvis, and growth of the primary lesion (Figure 2B). MRI of the brain and spinal axis revealed no cord compression, but two brain metastases in the left pre-central gyrus and left corona radiata were identified (Figure 2A). His next brain MRI in May 2017 revealed complete resolution of the two lesions (Figure 2). The patient's most recent imaging in May 2020 showed a stable 4.6 cm left renal lesion with stable small pulmonary lesions and no other evidence of disease (Figures 2C,D).