PMC2808615_01
Colonoscopic findings at admission. (A) Colonoscopy showing granular & reddish mucosal thickening in the rectum just above anus. (B) Colonoscopy showing reddish inflammatory mucosal swelling in the appendiceal orifice.
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F1
Colonoscopic examination revealed two lesions 1) a granular & reddish mucosal thickening at the just above rectum (Fig. 1A), and 2) a reddish inflammatory mucosa without elevation or depression at the appendiceal orifice (Fig. 1B).
Histologic findings of biopsy specimens. (A) Neoplastic lymphoid cells infiltrated colonic gland resembling a lymphoepithelial lesion (H&E, x200). (B) Immunohistochemical stain for CD 20 showing diffuse reaction in the cell membrane. Lymphoepithelial lesions (arrow heads) are also positive for CD20 (x200).
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F2
Microscopic examination of the mucosal lesions of the colon and rectum showed lymphoepithelial lesions consisting of diffuse proliferation of small lymphocytes and some glandular destruction by lymphocytes (Fig. 2A). Immunohistochemistry showed the neoplastic cells were positive for CD20 (Fig. 2B) but negative for CD5, CD10, and cyclin D1.
Colonoscopic findings after treatment. (A) Colonoscopy showing no definitive abnormal lesions in the rectum just above anus. (B) Colonoscopy showing normal appendiceal orifice.
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F3
Three months after treatment, a follow-up colonoscopy revealed no abnormal mucosa (Fig. 3).