PMC5843184_01
Proposed mechanisms involved in Cryptococcus-induced visual loss. (a) Normal, (b) inflammation/infiltration, (c) papilloedema and (d) Compartment syndrome.
HIVMED-16-305-g002.jpg
PMC5843184_01_HIVMED-16-305-g002.jpg
F0002
Lipson et al. first described two cases of AIDS-associated cryptococcal arachnoiditis resulting in bilateral visual loss secondary to an optic neuropathy (Figure 2b). We have reported a case that demonstrates the strong likelihood of ONSCS which we propose as a probable third mechanism of optic nerve dysfunction (Figure 2d).
PMC5843184_02
(a-h), Illustrative case of optic nerve sheath compartment syndrome.
HIVMED-16-305-g003.jpg
PMC5843184_02_HIVMED-16-305-g003.jpg
F0003
In addition to the blockage within the optic canals bilaterally, dilatation of the peri-optic CSF space ahead of the obstruction is visible on the left side (Figure 3).