PMC5292651_01
MRI of the tongue revealed the presence of a well-circumscribed nodule on the right anterior tongue, homogeneously isointense to muscle on T1WI (A) and homogeneously hyperintense on T2WI (B), showing hypervascularity on contrast dynamic study, with homogeneous contract enhancement (D).. A - T1 WI sagittal (TE: 13; TR: 590); B - T2 WI coronal (TE: 63; TR: 3340); T1 VIBE before (C) and after (D) gadolinium injection (TE: 12; TR: 624).
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T1WI and homogeneously hyperintense on T2WI, showing homogeneous hypervascular enhancement in the contrast dynamic study (Fig. 1). MRI was unable to make a definite diagnosis, however reported the benign characteristics of the lesion. The mass was excised under local anesthesia.
Histological pictures coloured with H&E (A, B and C) and immunohistochemical staining for S-100 protein (D).. A - At low power (H&E x 40) the capsule can be seen (arrow) as well as the Antony A (more cellular) and Antony B (paucicellular and more myxoid) components. B - At low power (H&E x 40) the ulcerated margin is evident, with haemorrhage and necrosis. C - At high power (H&E x 100) the palisading nuclei and Verocay bodies are evident, as well as the Antony A and Antony B components. The hypervascularity of the lesion can be noted, as many vessels are seen. D - Immunohistochemical staining revealed diffuse and strong positivity for S-100 protein.
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The histopathological and immunohistochemical examination confirmed the diagnosis of schwannoma (Fig. 2).