PMC6535821_01
Cardiac MRI showing mass in lateral wall of the left ventricle on T1 and T2 imaging.
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MRI was performed and showed a large mass, involving right ventricular (RV) lateral wall with a maximum thickness of 3 cm. Mass was hyperintense to myocardium on T2 and isointense on T1 (Figure 1).
(a) H&E section of cardiac biopsy showing diffuse infiltration of large cells. (b) Immunohistochemistry staining positive for CD20.
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Immunohistochemistry (IHC) markers on the mass were positive for CD45, CD20, PAX-5, BCL2, BCL6, and MUM-1 and negative for CD5, CD10, and cyclin D1 (Figure 2).
PET scan showing (a) increased FDG uptake in the cardiac tissue and (b) no extra cardiac FDG uptake.
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The PET scan showed increased FDG (F-18 fluorodeoxyglucose) uptake in right atrium, right ventricle, and left ventricle with no abnormal uptake outside of the heart (Figure 3).