PMC3420513_01
Neuroblastoma CNS metastasis treated with Gamma Knife stereotactic radiosurgery. (a) A T1-weighted brain magnetic resonance (MR) image from patient 1 following gadolinium administration demonstrates a 4.0 x 3.3 cm mass in the right parietal lobe. A thin rim of enhancement surrounds the lesion, which contains both cystic and solid components. (b) A T1-weighted brain MR image from patient 1 with gadolinium administration two months following stereotactic radiosurgery (SRS) reveals contraction of the lesion. A reduction in the enhancing components is also demonstrated, though proteinaceous components are still seen within the lesion. (c) and (d) A screenshot of the Leksell GammaPlan 4C treatment planning software is shown for patient 1. The right parietal lesion is targeted in this sequence. A 3D illustration confirms (d) minimal toxicity to surrounding structures.
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fig1
Brain magnetic resonance imaging (MRI) showed a 4.0 x 3.3 cm mass in the right parietal lobe with a small amount of surrounding edema and midline shift (Figure 1(a)). The patient was treated emergently with dexamethasone and subsequently underwent SRS (Figures 1(c) and 1(d)). Follow-up imaging 2 and 4 months later revealed a stable decrease in the size of the mass (Figure 1(b)).
PMC3420513_02