A tendency for magnesium deficiency in patients with diabetes mellitus is well established. Hypomagnesemia is commonly associated with hypokalemia and hypocalcemia. Here, we report a case of a 55 yr old woman with diabetes mellitus, presenting with acute onset quadriparesis, paresthesia and muscle cramps, associated with hypokalemia, hypomagnesemia and hypocalcemia, with total recovery on correction of electrolytes for which no other secondary cause could be ascertained.