This case report describes the successful treatment of a patient with facial asymmetry secondary to temporomandibular joint ankylosis with a combined orthodontic-surgical approach. Presurgical orthodontics involved surgically assisted rapid maxillary expansion followed by a bilateral sagittal split osteotomy and LeFort I osteotomy to reposition the mandible and correct the canting of the maxilla. The total active treatment period was 24 months. A significant improvement in occlusion and facial esthetics was achieved with treatment.