Eccrine angiomatous hamartoma is a rare, benign condition. Patients typically present with a solitary, sometimes enlarging nodule of the extremities usually appearing at birth or arising during childhood. Eccrine angiomatous hamartoma is usually sporadic, but one familial case of the multifocal variant has been reported. It is recognized histologically by increased numbers of eccrine elements as well as numerous vascular channels and proliferation of other dermal elements such as adipose tissue and hair follicles. When symptomatic, eccrine angiomatous hamartoma may be associated with hyperhidrosis or pain. We report a case of a 52-year-old woman with eccrine angiomatous hamartoma on the face and share our experience with botulinum toxins in the treatment of this condition.