Acute myeloid leukemia (AML-M7) is a type of pediatric AML accounting for 3-10% of primary childhood AML and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions. We report a rare case of AML .A 26-month-old boy who presented with weakness and fatigue. He was diagnosed as a case of AMLM-7 on the basis of peripheral blood finding, bone marrow examination report and immune phenotyping.