A 75-year-old Caucasian female with a full-thickness macular hole underwent a successful surgical repair. Vision improved from 20/400 to 20/30 after surgery. Two years later, the patient presented with a decreased vision after a fall onto her face with a reopened full-thickness macular hole. Vision decreased to 20/400 and then she underwent a second surgery with an internal limiting membrane peeling, which resulted in a second successful closure of her macular hole. Vision following the second surgery was 20/100. Reopening of a surgically repaired macular hole commonly follows cataract surgery, epiretinal membrane formation, and development of cystoid macular edema. This case demonstrates that surgically repaired macular holes may reopen after trauma as well.