Lichen amyloidosis (LA) is one form of primary cutaneous amyloidosis, presented as discrete, lichenoid papules with itching, commonly involving the extensor surfaces of extremities. Scalp involvement is rarely reported in the literature. In this study, we reported a case of LA over the crown and vertex areas of the scalp. The lesions subsided with topical clobetasol propionate/all-trans retinoic acid compound ointment treatment for 2 months and achieved significant improvement.