Clostridium ramosum, despite being a common enteric bacterium, is not commonly identified as the cause of pathologic infections in humans. It was first identified by Veillion and Zuber in 1898 from a patient with pulmonary gangrene and appendicitis. After performing an extensive literature search of major databases, only a few cases of pathologic C. ramosum infection were found in the medical literature. In this piece of work, we add to existing research by presenting a case report of an 83-year-old female who presented with abdominal pain, fever, and shortness of breath, requiring ICU admission due to mesenteric ischemia and C. ramosum bacteremia.