Introduction:
There have been numerous reported opportunistic infections among HIV/AIDS patients. However, coexistence of Kaposi sarcoma and Molluscum contagiosum on the same site is a rare finding.
Case presentation:
A 37-year-old man poorly adherent to antiretroviral therapy presented with Molluscum contagiosum and Kaposi sarcoma occurring simultaneously on numerous skin lesions around mid-2017 at Usmanu Danfodiyo University Teaching Hospital, Sokoto State, Nigeria.
Management and outcome:
The patient was counselled and re-initiated on a second-line highly active antiretroviral therapy regimen. The patient's lesions resolved three months later.
Discussion:
The case is presented to improve the index of suspicion among clinicians and pathologists on such rare occurrences.