Renal cell carcinoma morbidity grows in most of countries. All over the world 200,000 new cases are diagnosed every year, and approximately 102,000 patients die of this disease, with an incidence of nearly nine cases per 100,000 inhabitants per year. That's why, renal cell carcinoma is a challenging field in the current oncology research. Among urologic tumors, renal cell carcinoma ranks third in terms of incidence after prostate carcinoma and transitional cell carcinoma of the bladder. Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90-95% of neoplasms arising from the kidney. Bilateral renal cell carcinoma (BRCC) is a rare disease with poor prognosis which accounts for 2-6% of all cases of renal cell carcinoma. Only a few case reports and series with a small number of patients with bilateral renal cell carcinoma can be found in the literature. We present an interesting clinical case of bilateral renal cell carcinoma with a total survival rate of more than 10 years.