Adult onset Still's disease (AOSD) often poses a diagnostic and therapeutic challenge and clinical guidelines are lacking. It is often diagnosed after a considerable delay; bone scintigraphy imaging may offer new imaging techniques for early diagnosis and successful therapy in follow-up examinations. We describe the liver and bone scan findings in a 21-year old female patient with AOSD, who had been having fever of high grade, recurrent and intermittent in character, associated with severe sore throat and joint pains. She had been extensively investigated for possible infectious disease. She had received antibiotics and antimalarial drugs without any response.