We present a patient affected by a rapid neurological decline that was connected to subacute partial thrombosis of the straight sinus and associated with dilated superficial and deep medullary veins. An MRI scan confirmed signal alterations compatible with vascular disease and partial thrombosis of the straight sinus associated with dilated superficial and deep medullary veins of the cerebral white matter. Later, another MRI scan showed a replacement of the extensive white matter signal abnormalities, on FSE T2 and FLAIR sequences, by chronic vascular lesions.