Small bowel obstruction (SBO) is an extremely common condition for hospitalization throughout the world. Although most causes of are due to post-operative adhesions, there are much less common causes which remain important to consider as differentials due to diagnostic and treatment implications. To the best of our knowledge, we are presenting the first case of SBO caused by Salmonella typhimurium induced terminal ileitis. We discuss how certain characteristics on CT imaging along with culture data led to our diagnosis and successful treatment.