Orbital inflammatory disease, sequel to epidemic keratoconjunctivitis is an uncommon finding in adult patients. A 36-year-old male presented at the clinic with a 4-day history of left ocular pain and a one-month history of left eye redness and watering. Visual acuity in the eye was 6/5, with reduced red-color saturation and light brightness appreciation. Left eye examination showed periorbital fullness, a palpably enlarged and tender lacrimal gland, conjunctival follicles with pseudomembranes, and restriction of extraocular motility. Magnetic resonance imaging showed homogenous enhancement of the left lacrimal gland, lateral rectus muscle, pre and post-septal soft tissues. A diagnosis of left orbital inflammatory disease secondary to epidemic keratoconjunctivitis was made and patient was treated with high dose oral steroids over the course of 7 weeks, with complete resolution of clinical symptoms. In conclusion, orbital inflammatory disease can develop following epidemic keratoconjuctivitis in adults with good clinical response to oral steroids. Clinicians should have a high index of suspicion when assessing adult patients for orbital inflammatory disease.