Objective:
To report the first case of duloxetine hydrochloride (DH)-induced oral lichenoid drug reaction (OLDR).
Clinical presentation and intervention:
A 57-year-old male patient presented with painful ulcerative lesions on the bilateral buccal mucosa of 2-year duration. The patient was on multiple drug therapy for his systemic ailments. After thorough evaluation for possible medical ailments and with the physician's consent, withdrawal of DH was done. The oral lesions were resolved after 2 weeks.
Conclusion:
In this case, DH induced OLDR.