This case report documents the clinical approach adopted for two permanent maxillary incisors with extrusive luxation in a 16-year-old boy. The proposed procedures involved reposition of both teeth, by digital pressure and stabilized by using semi-rigid splint for 2 weeks. Endodontic therapy was performed. Clinical and radiographic follow-up examinations were conducted at 6-month intervals for two years. Assessment revealed the absence of pulpal and periapical disease and the restoration of the maxillary incisors to a state of health and normal function. A long-term clinical and radiological follow-up is needed to prevent and precociously detect possible complications that may occur following a extrusive luxation.