Dog bite is a common skin injury, which mainly causes structural damage, infection, and psychological trauma. Among these complications, infection by oral flora from animals has a major effect on later treatment. Each animal has a relatively unique oral microbial flora, which has a potential risk of infection and affects the formulation of treatment plans. Although lymph node necrosis is a common disease in the medical field, distant metastatic abscess and lymph node necrosis caused by dog bite are still worthy of early clinical suspicion after a patient presents with a dog bite disease. A high index of suspicion is greatly significant in shortening the patient's hospital stay, promoting wound healing, and reducing psychological trauma of patients.