title: The Biological Basis of Cancer
author: Robert G. McKinnell
description: "This is a well written and interesting book that many non-specialists will find interesting and educational." <br />Immunology<br /><br />"Excellent introductory text that can be recommended to both undergraduates and postgraduates in the biological sciences." <br />The Times Higher Education Supplement<br /><br />"...an excellent textbook aimed at the undergraduate. It is easy to see how a young biology major taking this course could become interested in cancer research or cancer medicine." <br />Paul P. Carbone, Director Emeritus of the University of Wisconsin Comprehensive Cancer Center
zlib_text: EPICHLOROHYDRIN 
  CAS No. 106-89-8 
  First Listed in the Fourth Annual Report on Carcinogens 
  CH2
  Cl
  O
  CARCINOGENICITY
  Epichlorohydrin is reasonably anticipated to be a human carcinogen based on sufficient 
  evidence of carcinogenicity in experimental animals (IARC 1976, 1982, 1987, 1999). When
  administered by gavage, epichlorohydrin induced carcinomas and papillomas of the forestomach
  in male rats. 
  When administered by inhalation, the compound induced carcinomas and
  papillomas of the nasal cavity in male rats. Subcutaneous injection of epichlorohydrin produced
  local sarcomas in female mice.  Epichlorohydrin also was active as an initiator in a two-stage
  skin carcinogenesis study of female mice, but it did not induce tumors when applied alone to the
  skin.
  There is inadequate evidence for the carcinogenicity of epichlorohydrin in humans (IARC
  1976, 1982, 1987, 1999). One study of factory workers exposed to epichlorohydrin shows a 
  significant excess of respiratory cancer; however, some of