title: Cancer and the Search for Selective Biochemical Inhibitors
author: E.J. Hoffman
description: Praise for the First Edition:<br />The five authors all have a common background in the natural sciences but their professional careers have taken them to diverse positions inside or outside of academiaand this diversity is definitely one of the strongest aspects of the book.<br />- Michael Heinrich, Journal of Ethnopharmacology<br /><br />The book is well written with many photographsand well indexed and has good supplemental information and references at the end of each chapter<br />- Charles D. Hufford, University of Mississippi (Journal of Natural Products, 2000, 63, 735-738)
zlib_text: HYDRAZINE AND HYDRAZINE SULFATE 
  CAS Nos. 302-01-2 and 10034-93-2 
  First Listed in the Third Annual Report on Carcinogens 
  O 
  OH
  S 
  O 
  OH 
  H2N 
  NH2 
  H2N 
  NH2 
  Hydrazine 
  Hydrazine Sulfate 
  CARCINOGENICITY 
  Hydrazine and hydrazine sulfate are reasonably anticipated to be a human carcinogen
  based on sufficient evidence of carcinogenicity in experimental animals (IARC 1974, 1982, 
  1987, 1999). 
  When administered orally, hydrazine induced pulmonary adenomas and 
  adenocarcinomas in mice. Intraperitoneal injection of hydrazine induced reticulum cell sarcomas 
  of the mediastinum and myeloid leukemias in mice of both sexes (IARC 1974). 
  When 
  administered by inhalation, hydrazine induced alveolarogenic carcinomas and lymphosarcomas
  of the spleen in female mice (MacEwen et al. 1974). When administered orally, hydrazine 
  sulfate induced pulmonary adenomas and adenocarcinomas, hepatomas, and hepatocarcinomas in
  mice of both sexes. When administered by stomach tube, hydrazine sulfate induced lung
  