title: Molecular Exploitation of Apoptosis Pathways in Prostate Cancer (Molecular Medicine and Medicinal Chemistry)
author:  Natasha Kyprianou 
description: This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of resistance by androgen-independent tumors are introduced, in terms of the contribution of anoikis and cross-talk of androgens with key growth factor signaling pathways. This volume also provides insightful discussion on the exploitation of the apoptotic and angiogenic synergism towards complete eradication of prostate tumors. Last but not least, it includes reflections on the drug development challenge based on analysis of data from existing clinical trials.
zlib_text:  
   
  Molecules 2020, 25, 1240; doi:10.3390/molecules25051240 
  www.mdpi.com/journal/molecules 
  Article 
  Induction of Apoptosis by  
  Gluconasturtiin‐Isothiocyanate (GNST‐ITC) in 
  Human Hepatocarcinoma HepG2 Cells and Human 
  Breast Adenocarcinoma MCF‐7 Cells 
  Asvinidevi Arumugam 1, Muhammad Din Ibrahim 1, Saie Brindha Kntayya 1,  
  Nooraini Mohd Ain 1, Renato Iori 2, Stefania Galletti 2, Costas Ioannides 3 
  and Ahmad Faizal Abdull Razis 4,5,6,* 
  1  UPM‐MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM 
  Serdang, Selangor, Malaysia; ashvini6050@gmail.com (A.A.); marc_dean89@yahoo.com (M.D.I.); 
  saiebrindhak@yahoo.co.uk (S.B.K.); noorainim@upm.edu.my (N.M.A.) 
  2  CREA Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria, Centro di Ricerca Agricoltura 
  e Ambiente (CREA‐AA), 40128 Bologna, Italy; renato.iori48@gmail.com (R.I.);  
  stefania.galletti@crea.gov.it (S.G.) 
  3  Faculty of Health and Medical Sciences, University of Surrey