title: Current Research in Protein Chemistry: Techniques, Structure and Function (v. 1)
author: Joseph J. Villafranca
description: This current research in Protein Chemistry: Techniques, Structure and Function.
zlib_text:  ORIGINAL PAPER
  Extremophiles  (2002)  6:245–251  
  © Springer-Verlag 2002
  Digital Object Identiﬁer (DOI) 10.1007/s00792-001-0249-0
  Communicated by G. Antranikian
  P.G. Sørensen • G. Dandanell (*)
  Department of Biological Chemistry, Institute of Molecular Biology, 
  University of Copenhagen, Sølvgade 83 H, 1307 Copenhagen K, 
  Denmark
  Tel. +45-3532-2025; Fax +45-3532-2040
  e-mail: dandanell@mermaid.molbio.ku.dk
  Springer-VerlagTokyoExtremophilesExtremophiles007921431-06511433-4909s00792-001-0249-00249Springer-VerlagOriginal Paper
  Abstract Dihydroorotate dehydrogenase (DHOD) (EC
  1.3.3.1) from the thermoacidophilic archaeon Sulfolobus
  solfataricus P2 (DSM 1617) was partially puriﬁed 3,158-
  fold, characterized, and the encoding genes identiﬁed.
  Based on enzymological as well as phylogenetic methods,
  dihydroorotate 
  dehydrogenase 
  from 
  S. 
  solfataricus
  (DHODS) represents a new type of DHOD, type 1S.
  Furthermore, it is unable to use any of the (type-speciﬁc)
  natural electron acceptors employed b