title: Crystal Structure Analysis: A Primer (International Union of Crystallography Texts on Crystallography)
author:  Jenny Pickworth Glusker 
description: <br />Jenny Pickworth Glusker took her doctorate at Oxford, before moving to the US for postdoctoral work at the California Institute of Technology in 1955. She is now Senior Member Emeritus at the Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, and Adjunct Professor of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA. She has held various senior positions, including President of the American Crystallographic Association (1979), Chair of the U.S. National Committee for Crystallography (1982-1984), and visiting professorships at several universities worldwide. Awards include the Garvan Medal, American Chemical Society (1979), the Public Service Award, American Crystallographic Association (1991) and the Fankuchen Award, American Crystallographic Association (with Ken Trueblood, 1995).<br /><br /> Kenneth N. Trueblood took his Ph.D. in chemistry at the California Institute of Chemistry in 1947. He remained at the University of California, Los Angeles until his death in 1998. For his profound influence on beginning chemistry students, he received the first UCLA Distinguished Teaching award (1961) and the national award for excellence in teaching given by the Manufacturing Chemists Association in 1978. For his work he received a Fulbright award (1956-1957), a Guggenheim fellowship (1976-1977), and the Fankuchen Memorial award of the American Crystallographic Assn (1995). He was elected President of the American Crystallographic Association in 1961. <br /><br /><br />
zlib_text: C H A P T E R
  12
  Molecular Scene Analysis: 
  Crystal Structure Determination
  Through Imagery
  Janice I. Glasgow, Suzanne Fortier & Frank H. Allen
  1 Introduction
  This chapter describes the design of a prototype knowledge-based system
  for crystal and molecular structure determination from diffraction data. This
  system enhances current methods for the determination and interpretation of
  protein structures by incorporating direct methods probabilistic strategies,
  experience accumulated in the crystallographic databases, and knowledge
  representation and reasoning techniques for machine imagery. The process of
  determining the structure of a crystal is likened to an iterative scene analysis,
  This paper is based on "Crystal and Molecular Scene Analysis," by Glasgow, Fortier
  and Allen which appeared in the Proceedings of the Seventh IEEE Conference on Ar-
  tificial Intelligence Applications, Miami Beach, Florida, Feb. 1991
  
  which draws both from the long-term memory of structural motifs and the
  ap