title: Tumors in Domestic Animals
author: Donald J. Meuten
description: "The fifth edition of Tumors in Domestic Animals has some substantial changes from the previous edition, the most immediately striking of which is the inclusion of color, which greatly adds to the illustrative power of the images. This edition contains several new chapters and updates to other chapters. Particularly noteworthy are the new chapters on trimming tissue specimens for submission and immunohistochemistry and updates to chapter 1, the section on lymphoma, and the diagnostic and prognostic algorithms in the appendices. Overall, the information contained in this book reflects the substantial progress made in veterinary oncology during the 15 years since the previous edition was released"..... "Overall, this book is reasonably priced and should be in the library of anyone with an interest in veterinary pathology or clinical oncology." <b>(Reviewed by Claire Cannon, BVSc, DACVIM, University of Minnesota 15th June 2017 AVMA)<br /><br /></b>
zlib_text: ACRYLONITRILE 
  CAS No. 107-13-1 
  First Listed in the Second Annual Report on Carcinogens 
  H2C
  CH
  C
  N
  CARCINOGENICITY
  Acrylonitrile is reasonably anticipated to be a human carcinogen based on sufficient 
  evidence of carcinogenicity in experimental animals (IARC 1979, 1982, 1987, 1999, ATSDR
  1990).
  When administered orally (by gavage or in drinking water), acrylonitrile induced 
  increased incidences of forestomach squamous cell papillomas, central nervous system
  microgliomas, mammary gland carcinomas, and Zymbal gland carcinomas in rats of both sexes.
  Inhalation studies demonstrated that acrylonitrile induced Zymbal gland carcinomas, glial cell
  tumors, forestomach papillomas and acanthomas, and central nervous system neoplasms in rats
  of both sexes, mammary tumors and extrahepatic angiosarcomas in female rats, and
  hepatocellular tumors in male rats (IARC 1999). 
  There is limited evidence for the carcinogenicity of acrylonitrile in humans (IARC 1979,
  1982, 1987, 1999). An epidemiological 