original_query: What is the effect of using prednisone at doses 7-10 mg or higher for several weeks on the hypothalamic-pituitary-adrenal (HPA) axis?
query: What is the effect of using prednisone at doses 7-10 mg or higher for several weeks on the hypothalamic-pituitary-adrenal (HPA) axis?
answer: Using prednisone at doses of 7-10 mg or higher for several weeks can suppress and cause atrophy of the HPA axis.