original_query: What is the purpose of using Oxford Nanopore Technologies' MinION in detecting DNAm?
query: What is the purpose of using Oxford Nanopore Technologies' MinION in detecting DNA methylation?
answer: Oxford Nanopore Technologies' MinION is used to detect DNA methylation by passing DNA strands through a nanopore, producing electrical signals sensitive to epigenetic changes in nucleotides. A hidden Markov model (HMM) analyzes these signals to detect 5-methylcytosine (5mC) modifications, achieving 82% accuracy.