original_query: What happens to the membrane when it is partially destroyed?
query: What happens to the phospholipid membrane when it is partially destroyed by ethanol?
answer: When the phospholipid membrane is partially destroyed by ethanol, the interior of the membrane becomes more hydrophilic due to the presence of water molecules in the interior region.  Irreversible inverted-micelles form, with overlapping leaflets from opposite membranes creating strong interlocking between acyl chains.