original_query: What are the advantages of light sheet fluorescence microscopy (LSFM)?
query: What are the advantages of light sheet fluorescence microscopy (LSFM)?
answer: LSFM offers high speed (100-1000x faster than point-scanning methods), reduced photodamage and stress on living samples due to illuminating only the observed section, good optical sectioning leading to higher contrast images, and the ability to acquire 3D images.