original_query: What evidence suggests that the locus coeruleus norepinephrine system might be responsible for generating the P3b?
query: What evidence suggests that the locus coeruleus norepinephrine system might be responsible for generating the P3b?
answer: The temporal-parietal region, a potential origin of P3b, is densely populated by norepinephrine inputs.  Some evidence suggests the locus coeruleus norepinephrine system might be responsible, but because many related studies used animals, further research is needed.