diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..aa73e312ffd677a97e0a787d09ff2d787df61b41 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7766b14b409b90ddaf67568f238e7ef192707d13de622fbe676318b97175c130 +size 71342 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5560a7b1e5ca608b3dcce8e7a68bbb3c69bcbe1b --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 53, + "title": "Average number of proteins per term", + "value": 2.509433962264151 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..df0b5d093eac1d7c0e5fd0be6909df584e848cd4 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..69759c320a98bb578ec38c94d534e232b560761e --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.8313213703099388 1.3251908329560749 0.1851078650571973 0.9999805774303868 0.3689413141452748 3 Q9HB40,Q9H3G5 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0e7b1d1e8694ee50d2a2ff6ed45fbebec1ad2d7a --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "WNK1"], "leading_proteins": ["CPVL", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..db06e5a90b0306a14bb1b18901c922453de59264 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aada24acfe5b38a85453321453f7cfd0cc0f754ba5278618a84d3a7597015f74 +size 135021 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..532a19f384dcfa5c76e9b5696f4062ee6a151eb5 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:986219146963c035cf81bbd354628f502f66e30fcf1aae40d7eb4cf66b7acc55 +size 69984 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..34453992532534b991337c4de254568003a36e01 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 29, + "title": "Average number of proteins per term", + "value": 4.482758620689655 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b79a3cda16caac430eefcbc69072b10db908b9ef --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dd3cfe13276d494c8bbffc82cf9e50d535c6b34c --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M16, zinc-binding site [IPR001431] 0.7875354853065963 1.8569046998860383 0.0633247138028654 0.8500029253716822 0.2329305949827993 5 Q10713 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.5600778893389573 1.802681272320628 0.0714382850036332 0.8834499583876144 0.2329305949827993 36 Q14257,Q9BPX6,Q15293,P80303,Q96AY3,Q02818,Q9NWM8,Q9Y680,O43852 9 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..25cedf4807fc49ad71ab1faaa6ac8ba44328bbc4 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TLK2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "FKBP10", "FKBP14", "FKBP7", "MICU1", "NUCB1", "NUCB2", "PMPCA", "RCN1", "RCN2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ca98c5f36594d004e9f56b6e8f5417cc59668809 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fdbddb13c501bea36d93486ef75968723056f158 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e12ec0158fb0ec00dbbf8a39105335230ad22f8df1fdc59e703bc1a4b1f12bf +size 192713 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0260b13d0b89e3475cb18bdf78928c19109ec492 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c39a582cb637cf876cf3c2b604c41abef0d40d6d679938cba1e135c3f52422d7 +size 191179 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..80d3dabb50e639c5de54d48a55fa1050ba35e510 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "14-3-3 protein, conserved site [IPR023409]", "3": "Mini-chromosome maintenance, conserved site [IPR018525]", "4": "Kinesin motor domain, conserved site [IPR019821]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..54b7cee10901e05c9fb4bd686d4111bd0ab951bd --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66cb411cc4cf49188a0fe592abee0d158d082d38c30b1f27238e177867f23c7b +size 143481 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b6d38aa8b6e020f39678e94f9f90db8376281a37 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41059c679ab3fdeb75414c0818718f72498a4c1339616ba127d475b36ac13410 +size 141563 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6407d67215bf95e485c5b1b201d43a17fe349913 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f00e04232f7bac8c922cf9acb1e646181f9a7f224866540603ee62daa592abf7 +size 140500 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..fc59603a58f34f62abec7014ca91e5e511165a9b --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b35f54ab830ee3cda0085d3493d69dd69a02e3ea75c55496f5154a365b1afa4b +size 147844 diff --git a/interpro_conserved_site/basic/plot_4.png b/interpro_conserved_site/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3388111de6c5f2c19c4dfd76297c862bf1d39fbb --- /dev/null +++ b/interpro_conserved_site/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c361c575b1d647a10e44bf56e99b2872c51ae64459355e2af467a4a1789c9c85 +size 146945 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..11b433ef7adbdbbff3b20a285df665b9a14daa1e --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90bf999265354602aabcf370fc12cb300cdd120a2f2f39efc8a5f79937386cb8 +size 81717 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b4f881727e0db0f4c745890847a7904ad21dcb10 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.514368349118331 0.0119245814539405 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.003028417017274 0.0009934566258862 0.0039135152062846 1.7923085924657402e-06 2.2585304294532336e-06 +Intermediate filament protein, conserved site [IPR018039] 6 8 2.378297404196543 0.0173927916070879 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.0688460117016781 0.0001429815632908 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1d4fc05b7f73dc0bb4256b50ddb041ff2c82c90e --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 271, + "title": "Average number of proteins per term", + "value": 2.7232472324723247 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..79297a287a19e40d1f08f52f2c8980015dc331ce --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..195c1301b5d69c60c29ff7f1d1ecb26c2ed67867 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,26 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.855469405791352 2.514368349118331 0.0119245814539405 0.9612639132018368 0.3030843232245134 8 P28070,P28072,P49721,P20618,Q99436 5 +Intermediate filament protein, conserved site [IPR018039] 0.8244742411163702 2.378297404196543 0.0173927916070879 0.9913907502083104 0.3030843232245134 8 Q16352,P07197,P02545,P20700,P08670,Q03252 6 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.7157479091134373 1.7130980233913295 0.0866945076219583 0.9999999999787698 0.4513846617678456 7 O94788 1 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8203923834396181 1.6933575094618514 0.0903874375784066 0.999999999992919 0.4513846617678456 4 P48735 1 +Annexin repeat, conserved site [IPR018252] 0.7461552737983435 1.6912421852282606 0.0907905570565641 0.9999999999937204 0.4513846617678456 6 P50995,P09525,P20073,P08133 4 +ABC transporter-like, conserved site [IPR017871] 0.6043823596769968 1.5058918276510636 0.1320949448222967 1.0 0.4837531087411138 10 O15439,P08183 2 +14-3-3 protein, conserved site [IPR023409] 0.6495754408883098 1.2752669648096986 0.2022147662777094 1.0 0.5829808687368004 6 P63104,P62258,P31946,P61981,Q04917 5 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.7073147509239615 1.2429618253626469 0.2138819011359292 1.0 0.5864932954400027 4 Q8N4Q0 1 +AMP-binding, conserved site [IPR020845] 0.6081492836668299 1.2221534894584771 0.221649588592818 1.0 0.5947231535510266 7 Q9UKU0,O14975 2 +Ubiquitin interacting motif [IPR003903] 0.6123704295234127 1.1097852050157395 0.2670915961846229 1.0 0.6520884915858813 5 Q92783,P42566,O14964 3 +Syntaxin/epimorphin, conserved site [IPR006012] 0.5693908306847991 1.0432918434876894 0.2968131475810747 1.0 0.6994466347345325 7 Q86Y82,Q9P2W9 2 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.5466585285299476 0.9388116054268014 0.3478274793265397 1.0 0.7807538479273014 7 O94788 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.6356558286485741 0.6168832582755545 0.5373117302455317 1.0 0.9295437633688208 3 P04439 1 +Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.4641579828592765 0.4999984795760113 0.6170761480295175 1.0 0.9495984767649244 5 Q13011 1 +Guanylate kinase, conserved site [IPR020590] 0.4467710850050617 0.4984095566591396 0.6181954022830085 1.0 0.9495984767649244 7 Q9NZW5,Q14168,O14936 3 +Chromo domain, conserved site [IPR023779] 0.3520311933421021 0.1371013355845243 0.8909506967953236 1.0 1.0 6 Q13185,P45973,P83916 3 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.5942596216568687 0.112177045635449 0.9106830292073552 1.0 1.0 2 P63167 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4146818923327833 0.0858253475531786 0.931605256386228 1.0 1.0 3 O60568,O00469 2 +Histidine triad, conserved site [IPR019808] 0.5547945205479285 0.0748665769776413 0.9403208696073068 1.0 1.0 2 Q96C86 1 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.4006525285481234 0.0701499693333602 0.9440742948540586 1.0 1.0 3 Q9UBQ7,O43175 2 +Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.267235547494746 0.0448074364466509 0.964260797620678 1.0 1.0 14 Q06136,Q9Y394 2 +Mini-chromosome maintenance, conserved site [IPR018525] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +Actin, conserved site [IPR004001] 0.4589041095890286 0.029823458736584 0.9762078497197764 1.0 1.0 2 O96019 1 +Vinculin, conserved site [IPR000633] 0.3894324853228875 0.0209521495825599 0.9832838263873992 1.0 1.0 2 P35221 1 +Kinesin motor domain, conserved site [IPR019821] 0.2652927706902255 0.0162216896263958 0.987057531919894 1.0 1.0 11 Q14807,O95239,Q99661,Q8NI77,P33176,Q86Y91,P52732,Q12756,O00139,Q9Y496 10 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d1ab5b1966725fe8172925e7ac4544ab257203c2 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", 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0000000000000000000000000000000000000000..ed0dcae020ed499b2f8f46ed41a54df306b78fcb --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a96e1358abf753d0f9218e590ef8adda97852f3e4a64dadd021ab83c1764976f +size 145244 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..389e672143699057b64fd1241df55a666045c3bf --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6810f1dab5981b8d4c094191bd15186ad2ce40fdd6cee442f87bb78e4330d0cf +size 148925 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..dac7e581e53bc7f12c75c72c83c053e5222ecabd --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9c43e0e1491636d82a562c9780a3cbff4ea2acb5aca8765c9ce6d4ebd9338a7c +size 223415 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3e93db9f416552bde34ab54ed117d3f0c899db60 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA recognition motif domain [IPR000504] 59 120 3.246851476207065 0.0011668926709085 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 0.7738508929132797 1.0 0.5009621880385454 6.475268365067079e-09 3.6095231448241037e-16 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 6 2.406340589364151 0.0161132345597629 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0001206551353332 0.0014481500629001 0.0001778916397324 5.41373461507268e-06 0.0001575214550341 +Intermediate filament, rod domain [IPR039008] 6 8 2.378297404196543 0.0173927916070879 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.097689242801984 0.0004867641084232 +Major facilitator superfamily domain [IPR020846] 2 5 2.128277991519916 0.0333140417450632 1.8883495145631068 4.121359223300971 0.8776223597987594 0.2728824130413255 1.233496960525634 1.4580976091979958 1.2936014196902064 0.266909732326598 0.2246782895314235 1.0 0.2518545844225215 0.0348798008289802 0.1766336232289773 +EF-hand domain [IPR002048] 11 41 2.0041661887586675 0.0450522611356252 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.0015255239831104 0.0832266786690803 0.0027125023591425 2.7482625988568255e-05 0.0032143698496569 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..57d6ab8493a49c12960baec303c482d6ef44cae5 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 2558, + "title": "Average number of proteins per term", + "value": 2.168491008600469 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6ae8b541472bbf3ecb570c071dfda4ea71162849 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a57b835cf234a78cb530e7e36625db99e9980321 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,218 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +RNA recognition motif domain [IPR000504] 0.5224074647378475 3.246851476207065 0.0011668926709085 0.9495440370442044 0.3173603324666894 120 Q9Y5S9,Q8N684,P84103,Q96PK6,Q08170,Q15717,O95104,P23588,P23246,P31942,Q93062,Q8WVV9,Q8WXF1,Q13242,Q15233,P52597,Q9P2N5,Q14103,P55795,Q13151,P08621,Q99729,Q86U42,Q9NW64,Q9NWH9,O60506,Q92804,Q07955,Q9UKM9,P51991,P52756,P22626,Q9Y4C8,P09012,Q14011,Q86V81,P31943,Q13595,O14979,Q01844,Q9BWF3,P31483,O75494,O43390,P49756,P35637,Q96I25,Q8IY67,Q16629,P98175,P62995,P07910,P98179,Q96E39,Q9Y6M1,Q9UKA9,Q96T37,P38159,P09651 59 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9205279894643852 2.406340589364151 0.0161132345597629 1.0 0.3173603324666894 6 Q8WUJ1,O15173,Q9UMX5,O43169 4 +Intermediate filament, rod domain [IPR039008] 0.8244742411163702 2.378297404196543 0.0173927916070879 1.0 0.3173603324666894 8 Q16352,P07197,P02545,P20700,P08670,Q03252 6 +Major facilitator superfamily domain [IPR020846] 0.8535848461035487 2.1282779915199157 0.0333140417450632 1.0 0.3173603324666894 5 Q6NT16,Q9H2V7 2 +EF-hand domain [IPR002048] 0.5813509570200599 2.0041661887586675 0.0450522611356252 1.0 0.3173603324666894 41 Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q66K14,Q96AY3,Q02818,Q9NWM8,Q9Y680,O43852 11 +ERAP1-like C-terminal domain [IPR024571] 0.8854130530681732 1.946801813027099 0.0515584995294844 1.0 0.334737669534064 4 P55786 1 +Peptidase M16, C-terminal [IPR007863] 0.7517033645111342 1.8732101556787408 0.0610393704862177 1.0 0.3456729180820594 7 P22695,Q10713 2 +Peptidase M16, N-terminal [IPR011765] 0.7517033645111342 1.8732101556787408 0.0610393704862177 1.0 0.3456729180820594 7 P22695,Q10713 2 +L27 domain [IPR004172] 0.7860478571363222 1.8507089629812592 0.0642114339246266 1.0 0.3555256449766127 5 Q9NZW5,Q14168,O14936 3 +Zinc finger, RanBP2-type [IPR001876] 0.7024861316993796 1.820806756864724 0.0686362368396562 1.0 0.3661183589091307 8 P98175,P35637,Q92804 3 +LEM domain [IPR003887] 0.7719377394737437 1.8002788565136632 0.0718166177434109 1.0 0.3690666542490123 6 Q86XL3 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9585644371941244 1.798235538334289 0.0721396900408546 1.0 0.3690666542490123 3 Q13505,Q5HYI7 2 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9585644371941244 1.798235538334289 0.0721396900408546 1.0 0.3690666542490123 3 Q13505,Q5HYI7 2 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7680597632506372 1.7839450884098604 0.0744325883544183 1.0 0.3760444540449542 6 O15439,P08183 2 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8260443864229922 1.715593222372524 0.0862365198660186 1.0 0.4047578308573866 4 P07197,P08670,Q16352 3 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9310352253420646 1.6967514707447326 0.0897436571473431 1.0 0.4114075895472671 3 Q15629 1 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8203923834396181 1.6933575094618514 0.0903874375784066 1.0 0.4114075895472671 4 P48735 1 +K Homology domain, type 1 [IPR004088] 0.5396433758378766 1.684036419743563 0.0921746304772086 1.0 0.4118241097629579 23 Q96AE4,P61978,Q13868,Q92945,Q9Y6M1,Q96I24,O75525 7 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.738290581702346 1.657781389030862 0.0973615990989702 1.0 0.4118241097629579 6 P55786 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.738290581702346 1.657781389030862 0.0973615990989702 1.0 0.4118241097629579 6 P55786 1 +L27 domain, C-terminal [IPR014775] 0.7992172582415147 1.6097467286756102 0.1074531591144536 1.0 0.4176471792482675 4 Q9NZW5,O14936 2 +Zinc finger, CHHC-type [IPR012996] 0.9050570962479576 1.6004362469604982 0.1095018394155582 1.0 0.4218459416039126 3 P52597,P31943 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7108934661618375 1.5335016838198678 0.1251522920926053 1.0 0.4515367604695127 5 Q9HD20,P35670 2 +ABC transporter-like, ATP-binding domain [IPR003439] 0.6043823596769968 1.5058918276510636 0.1320949448222967 1.0 0.4641509975779994 10 O15439,P08183 2 +Reticulon [IPR003388] 0.8795517685860733 1.5054579055655006 0.1322063913882549 1.0 0.4641509975779994 3 O95197 1 +GOLD domain [IPR009038] 0.7023593005552159 1.5038428568813866 0.1326218332911812 1.0 0.4641509975779994 6 Q7Z7H5,P49755,Q9BVK6,Q9H3P7 4 +HDGF-related, PWWP domain [IPR035496] 0.7724946388397118 1.5036218888719846 0.1326787518277461 1.0 0.4641509975779994 4 P51858 1 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.7035832027722164 1.502264876267276 0.1330287158259047 1.0 0.4642393657335119 5 Q9UKU0,O14975 2 +Lamin tail domain [IPR001322] 0.8769983686786278 1.4959312569045973 0.1346715699971783 1.0 0.4691742078450181 3 P02545,Q03252 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.5451791681808908 1.4756008995910397 0.1400510635013701 1.0 0.4731654091309511 14 P19338,P31483,Q9Y4C8,Q14011,Q96I25,Q96E39,P38159 7 +Fibronectin type III [IPR003961] 0.6803054978811593 1.4086168810632904 0.1589484844904087 1.0 0.503947290882476 6 Q8NAT1,P10586 2 +K Homology domain [IPR004087] 0.4970667902924298 1.408260697724925 0.1590538888855126 1.0 0.503947290882476 22 Q96AE4,Q07666,P61978,Q92945,Q96PU8,Q9Y6M1,Q13601,Q96I24,O75525 9 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5673711241556938 1.3141784563607584 0.1887861566346238 1.0 0.5439442445733081 10 Q96AY3,Q9NWM8 2 +MHC class I-like antigen recognition-like [IPR011161] 0.6537523220619221 1.2881632990998362 0.1976891246222387 1.0 0.5575400008640427 5 P04439,Q9UNN8 2 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.651099137710503 1.2818914382092272 0.1998807318072453 1.0 0.5575866517565273 6 Q32P28,P13674 2 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.651099137710503 1.2818914382092272 0.1998807318072453 1.0 0.5575866517565273 6 Q32P28,P13674 2 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.7159972438904492 1.2777515297213484 0.201337049717255 1.0 0.5598550716231471 4 Q9UKA9 1 +14-3-3 domain [IPR023410] 0.6495754408883098 1.2752669648096986 0.2022147662777094 1.0 0.5610253493908683 6 P63104,P62258,P31946,P61981,Q04917 5 +Zinc finger, CCHC-type [IPR001878] 0.6185745491654258 1.2702394091357343 0.2039993637413517 1.0 0.5637550130100755 7 Q9BWF3 1 +Protein kinase, C-terminal [IPR017892] 0.6185253155885179 1.27001244756749 0.2040801962655707 1.0 0.5637550130100755 7 P17252 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.810766721044034 1.2483248207958904 0.2119121280865936 1.0 0.5746292982705569 3 O43823,Q5BKZ1 2 +AMP-dependent synthetase/ligase [IPR000873] 0.6081492836668299 1.2221534894584771 0.221649588592818 1.0 0.5828473537420891 7 Q9UKU0,O14975 2 +Arf GTPase activating protein [IPR001164] 0.7976220054302405 1.199231471652629 0.2304379530640592 1.0 0.5950548125336386 3 Q96P47 1 +LIS1 homology motif [IPR006594] 0.6292262573593788 1.1867378120766907 0.2353310552863972 1.0 0.6038862237387348 6 O95684,Q14978 2 +NOPS [IPR012975] 0.7827079934747052 1.1436398675821835 0.2527730207375525 1.0 0.618749652676229 3 Q15233,P23246 2 +Immunoglobulin subtype 2 [IPR003598] 0.5901688210682765 1.1391493490664706 0.254640867406108 1.0 0.6209450322448278 7 Q9BX67,P10586 2 +OCRE domain [IPR041591] 0.7795298520377618 1.1318134429124518 0.2577128748490582 1.0 0.6216472289094124 3 P98175 1 +Chromo domain subgroup [IPR017984] 0.7794453507340863 1.1314991092287712 0.2578450781363903 1.0 0.6216472289094124 3 Q13185,P45973 2 +Chromo shadow domain [IPR008251] 0.7794453507340863 1.1314991092287712 0.2578450781363903 1.0 0.6216472289094124 3 Q13185,P45973 2 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7722675367047148 1.1048211547091606 0.2692370920858185 1.0 0.6360435675375198 3 Q32P28,P13674 2 +Extended PHD (ePHD) domain [IPR034732] 0.6437578418987885 0.9893244969077212 0.3225044022979104 1.0 0.6974955485125786 4 Q03164 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.94487932159165 0.9850931734651038 0.32457830625562 1.0 0.6980561024273486 2 Q15067 1 +GRAM domain [IPR004182] 0.7351573654720264 0.9678471211757717 0.3331207264358644 1.0 0.7059841078897607 3 Q66K14 1 +Aldehyde dehydrogenase domain [IPR015590] 0.5072818371965085 0.933879026742028 0.3503662986965719 1.0 0.7213120659605242 9 O94788 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9256360078277874 0.920922519218299 0.3570908805467501 1.0 0.7266813623218669 2 O60506 1 +Diacylglycerol/phorbol-ester binding [IPR020454] 0.7214219935632105 0.9177048485308952 0.3587734086146372 1.0 0.7283669676478112 3 P17252 1 +B-box-type zinc finger [IPR000315] 0.5401871032141413 0.9092019050455274 0.3632435588092104 1.0 0.73221199640186 7 O15344,Q9C037,P19474 3 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9207436399217176 0.9047367703260482 0.3656048561683394 1.0 0.7331813052400186 2 Q14011 1 +MRH domain [IPR044865] 0.7123530471103202 0.8848135088190755 0.376257222343753 1.0 0.7446030471014071 3 P11717 1 +Complex 1 LYR protein domain [IPR008011] 0.9093281148075651 0.8671964654537149 0.3858343725737425 1.0 0.7531736982445644 2 Q5U5X0 1 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4808769680560074 0.8640304741955861 0.3875711501062535 1.0 0.7531736982445644 10 Q15067 1 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.5501438291515732 0.8444732724966212 0.3984049926183615 1.0 0.7611052808945248 5 Q9ULV3,Q15428,Q12874 3 +Linker histone H1/H5, domain H15 [IPR005818] 0.5486749046352667 0.8386781319741635 0.4016499529746409 1.0 0.7629753048048258 6 P07305,P16402,P10412 3 +Target SNARE coiled-coil homology domain [IPR000727] 0.4869539195680072 0.8321169721903494 0.4053429227594414 1.0 0.7674812704801267 9 P56962,Q86Y82,O95721 3 +Far upstream element-binding protein, C-terminal [IPR015096] 0.8959556425309819 0.8236607517376565 0.4101323462385773 1.0 0.7729091423383172 2 Q92945 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.6921753097403367 0.8123678700015248 0.4165805768880792 1.0 0.77782046176864 3 Q9BUJ2 1 +RBM1CTR [IPR012604] 0.8789954337899475 0.7692127922809486 0.4417669975516776 1.0 0.798050833147734 2 P38159 1 +EF-hand, Ca insensitive [IPR014837] 0.6720869484463592 0.741458368124536 0.4584155654419701 1.0 0.8137592063848437 3 O43707 1 +AGC-kinase, C-terminal [IPR000961] 0.4556553953466088 0.7352418629837233 0.4621922077733948 1.0 0.8170612767687243 10 P17252 1 +Post-SET domain [IPR003616] 0.5202303769299325 0.720374009649381 0.4712947478826292 1.0 0.8240409877537701 5 Q03164 1 +PWI domain [IPR002483] 0.519084549124967 0.7156908287530086 0.4741822750514424 1.0 0.8252314773254517 5 Q9P2N5 1 +G-patch domain [IPR000467] 0.4120783522889309 0.6986434105184562 0.4847749073729113 1.0 0.8338991443633454 14 Q8IWZ8,Q92917,P78332,Q96I25,P98175,P52756 6 +Stromalin conservative domain [IPR020839] 0.8561643835616419 0.6974793339210389 0.4855028681798916 1.0 0.8338991443633454 2 Q8WVM7 1 +STAG [IPR013721] 0.8561643835616419 0.6974793339210389 0.4855028681798916 1.0 0.8338991443633454 2 Q8WVM7 1 +Zinc finger, C3HC4 RING-type [IPR018957] 0.6584013050570916 0.6939862675235176 0.4876908209411903 1.0 0.8338991443633454 3 Q63HN8,O75150 2 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.4689118961128093 0.6891808831155881 0.4907094454453511 1.0 0.8349274172283256 8 P05771,P17252 2 +Methyltransferase type 11 [IPR013216] 0.8509458577951693 0.6813645169766881 0.4956408690937435 1.0 0.8349274172283256 2 Q8N6R0 1 +Amine oxidase [IPR002937] 0.6537106509784831 0.6778920167073105 0.4978401621258363 1.0 0.8349274172283256 3 Q8NB78 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.6454001225312772 0.649617557113852 0.5159392892762025 1.0 0.8453004608382401 3 P16615 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.6454001225312772 0.649617557113852 0.5159392892762025 1.0 0.8453004608382401 3 P16615 1 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.4813263355771069 0.6453388358251165 0.5187076307571072 1.0 0.8478301082918085 7 Q8N8N7 1 +Immunoglobulin C1-set [IPR003597] 0.5535908852944853 0.6427055390238321 0.5204151862084438 1.0 0.8495354475566045 4 P04439,P55899 2 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.4992444364803853 0.6327166924530472 0.5269186672261008 1.0 0.8525350732222429 6 Q99956 1 +Forkhead-associated (FHA) domain [IPR000253] 0.4440800972590856 0.6223361504717508 0.5337208551308941 1.0 0.8586527971225327 9 Q9BWU0,P85037 2 +CARG-binding factor, N-terminal [IPR012956] 0.8212654924983622 0.591991314347188 0.5538564046212306 1.0 0.8710188175613914 2 Q99729 1 +Glycosyltransferase 2-like [IPR001173] 0.527059276182525 0.54722885103746 0.5842215173500114 1.0 0.8948734379528916 4 Q10472,Q86SF2 2 +Zinc finger, CW-type [IPR011124] 0.8039791258969222 0.5419416710675596 0.5878586887495001 1.0 0.8962581970012385 2 Q8NB78 1 +G-protein gamma-like domain [IPR015898] 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 0.9231185075273864 2 Q9UBI6 1 +Butyrophylin-like, SPRY domain [IPR003879] 0.4605569385663421 0.486606979109414 0.6265368767731341 1.0 0.9258702084261564 5 O15344,P19474 2 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.7831050228310368 0.4837557368563144 0.6285592318074245 1.0 0.9261401160171728 2 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.7831050228310368 0.4837557368563144 0.6285592318074245 1.0 0.9261401160171728 2 Q9Y282 1 +DZF domain [IPR006561] 0.5061327310146106 0.4751961103472947 0.6346471992504013 1.0 0.9263619561277956 4 Q96KR1 1 +Sam68, tyrosine-rich domain [IPR032335] 0.7788649706457798 0.4722621910543184 0.6367396539765711 1.0 0.9263619561277956 2 O75525 1 +KHDRBS, Qua1 domain [IPR032571] 0.7788649706457798 0.4722621910543184 0.6367396539765711 1.0 0.9263619561277956 2 O75525 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.7778864970645771 0.4696261687146495 0.6386221250286659 1.0 0.9263619561277956 2 Q5T9A4 1 +Glycosyl transferase, family 1 [IPR001296] 0.7769080234833534 0.4669963365247901 0.6405024991274086 1.0 0.9263619561277956 2 Q2TAA5 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.5885438286746305 0.4662617512346461 0.6410281532350257 1.0 0.9264124384040654 3 Q10472 1 +Ricin B, lectin domain [IPR000772] 0.5022112366972683 0.462069821279517 0.6440312510835484 1.0 0.9283105319248371 4 Q10472 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7720156555772923 0.4539410998973208 0.6498712207946993 1.0 0.9318220755565252 2 P13674 1 +PWWP domain [IPR000313] 0.3953788190431937 0.443142782785952 0.6576624615979771 1.0 0.9382602212870192 10 Q7Z4V5,P51858 2 +Histone H2A/H2B/H3 [IPR007125] 0.4961603058965348 0.442066060059772 0.6584414035019832 1.0 0.938269069873587 4 P84243 1 +Guanylate kinase-like domain [IPR008144] 0.4030157317430818 0.4327417347108977 0.6652024064717825 1.0 0.9399120909390128 9 Q9NZW5,Q14168,O14936 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4030157317430818 0.4327417347108977 0.6652024064717825 1.0 0.9399120909390128 9 Q9NZW5,Q14168,O14936 3 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.4381348992050725 0.405909333332081 0.6848092200143803 1.0 0.9399120909390128 5 Q15024,Q9NQT4 2 +B30.2/SPRY domain [IPR001870] 0.3767909489909189 0.4051474514140163 0.6853691286216719 1.0 0.9399120909390128 11 P19474,O15344,Q9BUJ2,Q96S59,Q9C037,Q9UBL3 6 +SPRY domain [IPR003877] 0.3767909489909189 0.4051474514140163 0.6853691286216719 1.0 0.9399120909390128 11 P19474,O15344,Q9BUJ2,Q96S59,Q9C037,Q9UBL3 6 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.7393998695368409 0.371160180101673 0.7105182298111636 1.0 0.9500414257390238 2 Q7Z4V5 1 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.7351598173515954 0.3609764409165053 0.7181170587766366 1.0 0.9547179738950452 2 Q9H993 1 +BTB/POZ domain [IPR000210] 0.7348336594911902 0.3601988658135787 0.7186984228148019 1.0 0.9547179738950452 2 Q08380 1 +Rho GTPase-activating protein domain [IPR000198] 0.4222992451981617 0.3520585051618707 0.7247943867443691 1.0 0.9551901294652736 5 O00459,Q9H0H5 2 +Heat shock chaperonin-binding [IPR006636] 0.5471451876019429 0.3471916271584371 0.728447360641105 1.0 0.9565545936960712 3 P31948,Q9NRR5 2 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.7266797129810811 0.3410325759865238 0.7330790580868509 1.0 0.9567851845661444 2 P31949 1 +B-box, C-terminal [IPR003649] 0.4614952960972716 0.334010991614289 0.7383712644270404 1.0 0.958924062537347 4 O15344 1 +Brix domain [IPR007109] 0.4139732288605945 0.3249213761972292 0.7452405780661038 1.0 0.958924062537347 5 Q96G21,Q9H7B2,Q9H9Y2,Q9NQ55 4 +DnaJ domain [IPR001623] 0.3302137747223827 0.3199660265450861 0.7489940846463301 1.0 0.958924062537347 16 Q96EY1,Q8IXB1,Q13217,Q99615,Q99543,O14976,P31689,Q9NXW2 8 +DNA binding HTH domain, Psq-type [IPR007889] 0.7152641878669135 0.3151030209068437 0.7526834349212785 1.0 0.9606441007615772 2 P07199 1 +FCP1 homology domain [IPR004274] 0.7080887149380203 0.2993599051346824 0.7646654512353208 1.0 0.9614334070308412 2 Q3ZCQ8 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.703522504892361 0.2895700720393325 0.7721451655154874 1.0 0.962267742911338 2 Q08170 1 +Band 7 domain [IPR001107] 0.3769186186596123 0.2868503349822348 0.7742269199358014 1.0 0.962267742911338 8 Q99623,O75477,Q14254,Q9UJZ1 4 +Exoribonuclease, phosphorolytic domain 2 [IPR015847] 0.4428617602324606 0.2811754575787351 0.7785758276411485 1.0 0.962267742911338 4 Q15024 1 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.5184339314844857 0.2738084522135241 0.7842318278390359 1.0 0.962267742911338 3 Q92688,P09661 2 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.3996976679236299 0.2687842759956961 0.7880956941539803 1.0 0.9636770238118684 6 Q8N4Q0 1 +Domain of unknown function DUF1087 [IPR009463] 0.6868884540117363 0.2554485576022743 0.7983766708761948 1.0 0.9636770238118684 2 Q12873 1 +CHD, N-terminal [IPR012958] 0.6868884540117363 0.2554485576022743 0.7983766708761948 1.0 0.9636770238118684 2 Q12873 1 +CHD subfamily II, SANT-like domain [IPR009462] 0.6868884540117363 0.2554485576022743 0.7983766708761948 1.0 0.9636770238118684 2 Q12873 1 +CHD, C-terminal 2 [IPR012957] 0.6868884540117363 0.2554485576022743 0.7983766708761948 1.0 0.9636770238118684 2 Q12873 1 +Chaperone DnaJ, C-terminal [IPR002939] 0.4285248041775473 0.2433547760753636 0.8077305742907677 1.0 0.9636770238118684 4 P31689,Q96EY1,O60884 3 +Ribosomal L28e/Mak16 [IPR029004] 0.6754729288975718 0.2334667364723671 0.815398996359523 1.0 0.9636770238118684 2 Q9BXY0 1 +Marvel domain [IPR008253] 0.6748206131767603 0.232246575930525 0.8163465041871412 1.0 0.9636770238118684 2 Q16625 1 +CAP Gly-rich domain [IPR000938] 0.4998368678629624 0.2308759672278004 0.817411161751616 1.0 0.9636770238118684 3 Q99426,Q15813 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.4994297269781027 0.2299788790774574 0.8181081819201628 1.0 0.9636770238118684 3 P04439 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.4994297269781027 0.2299788790774574 0.8181081819201628 1.0 0.9636770238118684 3 P04439 1 +EF hand associated, type-1 [IPR013566] 0.6598173515981619 0.2052701786429463 0.8373610419403112 1.0 0.9678709894805378 2 Q8IXI1 1 +MIRO domain [IPR020860] 0.6598173515981619 0.2052701786429463 0.8373610419403112 1.0 0.9678709894805378 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.6598173515981619 0.2052701786429463 0.8373610419403112 1.0 0.9678709894805378 2 Q8IXI1 1 +CTLH, C-terminal LisH motif [IPR006595] 0.6585127201565482 0.2030235749591268 0.8391166057670512 1.0 0.9678709894805378 2 Q96S59 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.6559034572733109 0.1985782737508529 0.8425926501705892 1.0 0.9678709894805378 2 Q8TAQ2 1 +SMARCC, N-terminal [IPR032450] 0.6559034572733109 0.1985782737508529 0.8425926501705892 1.0 0.9678709894805378 2 Q8TAQ2 1 +SMARCC, C-terminal [IPR032451] 0.6559034572733109 0.1985782737508529 0.8425926501705892 1.0 0.9678709894805378 2 Q8TAQ2 1 +Myosin tail [IPR002928] 0.484176182707974 0.1977348617486674 0.8432525124714114 1.0 0.9678709894805378 3 P35579,P35580 2 +SPRY-associated [IPR006574] 0.3994794940119331 0.174984572510416 0.8610917559055231 1.0 0.9737721978807816 4 O15344 1 +PABP, RNA recognition motif 2 [IPR045305] 0.6373124592302591 0.1687627029587086 0.8659832961922405 1.0 0.9758525425813882 2 Q13310 1 +Plectin/S10, N-terminal [IPR005326] 0.6356816699282356 0.1663030786858191 0.8679184433445299 1.0 0.9760909744316572 2 P46783 1 +SAP domain [IPR003034] 0.2990982118847502 0.1477218450413593 0.8825622909285262 1.0 0.9841300523954534 14 Q8IV48,Q9BUJ2,P82979,Q9NWH9 4 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.4486133768352246 0.1332258424437858 0.8940147737028006 1.0 0.9853494980662107 3 Q96EY1,P31689 2 +Syntaxin, N-terminal domain [IPR006011] 0.3777652008749628 0.131570373750209 0.8953241200916926 1.0 0.9853494980662107 4 Q86Y82 1 +Zinc finger, FYVE-related [IPR017455] 0.4437442570817592 0.1255781835230698 0.9000658332489531 1.0 0.9853494980662107 3 O14964 1 +FYVE zinc finger [IPR000306] 0.4437442570817592 0.1255781835230698 0.9000658332489531 1.0 0.9853494980662107 3 O14964 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 0.9853494980662107 3 Q06323,Q9UL46 2 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 0.9853494980662107 3 Q06323,Q9UL46 2 +SWIB domain [IPR019835] 0.6043705153294071 0.1239242844169211 0.901375224970654 1.0 0.9853494980662107 2 Q92925 1 +SWIB/MDM2 domain [IPR003121] 0.6043705153294071 0.1239242844169211 0.901375224970654 1.0 0.9853494980662107 2 Q92925 1 +FAD dependent oxidoreductase [IPR006076] 0.3635223459013686 0.1067978033861024 0.9149493901536436 1.0 0.99466236294646 4 Q96CU9 1 +High mobility group box domain [IPR009071] 0.3063815300414729 0.1004228932734599 0.9200085954304758 1.0 0.9961422562025386 10 P17480,Q969G3 2 +Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108] 0.5825179386823081 0.0996851013362966 0.9205943290315876 1.0 0.9961422562025386 2 Q9UKF6 1 +Beta-Casp domain [IPR022712] 0.5825179386823081 0.0996851013362966 0.9205943290315876 1.0 0.9961422562025386 2 Q9UKF6 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.3280181995759746 0.0954963388703628 0.9239205981300624 1.0 0.9989448938144512 7 Q8N4Q0 1 +CTP synthase, N-terminal [IPR017456] 0.571102413568152 0.0886905590512124 0.9293278357527914 1.0 1.0 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.571102413568152 0.0886905590512124 0.9293278357527914 1.0 1.0 2 P17812 1 +VHS domain [IPR002014] 0.351733968376601 0.0885187457602332 0.9294643858587066 1.0 1.0 4 Q92783 1 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.4146818923327833 0.0858253475531786 0.931605256386228 1.0 1.0 3 O60568,O00469 2 +Dbl homology (DH) domain [IPR000219] 0.4107667210440451 0.0812267287797526 0.9352616432517378 1.0 1.0 3 P11274,Q8N5V2 2 +EH domain [IPR000261] 0.3384464751958262 0.0702950680486279 0.9439588079254716 1.0 1.0 4 P42566,Q9H223,Q9H4M9 3 +D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.4006525285481234 0.0701499693333602 0.9440742948540586 1.0 1.0 3 Q9UBQ7,O43175 2 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.4006525285481234 0.0701499693333602 0.9440742948540586 1.0 1.0 3 Q9UBQ7,O43175 2 +La-type HTH domain [IPR006630] 0.3076310839876908 0.068869516326528 0.945093483335398 1.0 1.0 5 Q92615 1 +Ribosomal protein L18e/L15P [IPR021131] 0.3962348235507981 0.0656677303967384 0.9476423643510848 1.0 1.0 3 Q9P015 1 +U-box domain [IPR003613] 0.3162672548510337 0.0630054148409362 0.9497621924707748 1.0 1.0 6 P19474 1 +NET domain [IPR027353] 0.5225048923678876 0.053480282896314 0.9573492401335064 1.0 1.0 2 O60885 1 +Brdt, bromodomain, repeat I [IPR043508] 0.5225048923678876 0.053480282896314 0.9573492401335064 1.0 1.0 2 O60885 1 +Brdt, bromodomain, repeat II [IPR043509] 0.5225048923678876 0.053480282896314 0.9573492401335064 1.0 1.0 2 O60885 1 +Spt5 C-terminal domain [IPR024945] 0.5221787345074823 0.0533014173595724 0.9574917509193186 1.0 1.0 2 Q9UQ35 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630] 0.3771615008156614 0.0486883273329879 0.9611676782830184 1.0 1.0 3 P13995,P11586 2 +Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631] 0.3771615008156614 0.0486883273329879 0.9611676782830184 1.0 1.0 3 P13995,P11586 2 +SLIDE domain [IPR015195] 0.5097847358121158 0.047004579739875 0.96250957746054 1.0 1.0 2 P28370 1 +ISWI, HAND domain [IPR015194] 0.5097847358121158 0.047004579739875 0.96250957746054 1.0 1.0 2 P28370 1 +Zinc finger, MIZ-type [IPR004181] 0.5058708414872607 0.0452106511575326 0.9639394045365876 1.0 1.0 2 O75928 1 +Zinc finger, CCCH-type [IPR000571] 0.2695515611345472 0.0451682947283239 0.96397316558837 1.0 1.0 12 Q86VM9,Q9P2N5 2 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.5022831050228183 0.0436442217614939 0.9651880013930664 1.0 1.0 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.5022831050228183 0.0436442217614939 0.9651880013930664 1.0 1.0 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.5022831050228183 0.0436442217614939 0.9651880013930664 1.0 1.0 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.5022831050228183 0.0436442217614939 0.9651880013930664 1.0 1.0 2 A0FGR8 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.5022831050228183 0.0436442217614939 0.9651880013930664 1.0 1.0 2 A0FGR8 1 +MCM N-terminal domain [IPR027925] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +MCM domain [IPR001208] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +MCM OB domain [IPR033762] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +MCM, AAA-lid domain [IPR041562] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +eRF1 domain 1/Pelota-like [IPR005140] 0.493803000652296 0.0402259335167407 0.9679130024024384 1.0 1.0 2 Q9BRX2 1 +eRF1 domain 3 [IPR005142] 0.493803000652296 0.0402259335167407 0.9679130024024384 1.0 1.0 2 Q9BRX2 1 +eRF1 domain 2 [IPR005141] 0.493803000652296 0.0402259335167407 0.9679130024024384 1.0 1.0 2 Q9BRX2 1 +Domain of unknown function DUF5600 [IPR040990] 0.489562948467043 0.0386598612273825 0.9691615755689283 1.0 1.0 2 Q9H223 1 +EH domain-containing protein, N-terminal [IPR031692] 0.489562948467043 0.0386598612273825 0.9691615755689283 1.0 1.0 2 Q9H223 1 +Man1/Src1, C-terminal [IPR018996] 0.4856490541421939 0.0372948713434717 0.9702498947248032 1.0 1.0 2 Q9Y2U8 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.4797782126549132 0.0353863814854866 0.9717716439120307 1.0 1.0 2 Q15477 1 +rRNA-processing arch domain [IPR025696] 0.4797782126549132 0.0353863814854866 0.9717716439120307 1.0 1.0 2 Q15477 1 +Clp ATPase, C-terminal [IPR019489] 0.4621656881930712 0.0305767680356935 0.9756070699068518 1.0 1.0 2 Q9H078 1 +Staufen, C-terminal [IPR032478] 0.339641109298531 0.0253349863284293 0.9797877678259072 1.0 1.0 3 O95793,O75569 2 +Zinc finger, LIM-type [IPR001781] 0.2694012469892367 0.0252034378470389 0.9798926948231026 1.0 1.0 11 Q93052,Q96HC4 2 +R3H domain [IPR001374] 0.3370309951060368 0.0241409031829096 0.9807402167977224 1.0 1.0 3 O15226,O95453 2 +TATA box binding protein associated factor (TAF) [IPR004823] 0.4220482713633274 0.0237030512183882 0.9810894721704306 1.0 1.0 2 P62805 1 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.3979125896934066 0.0214935112574544 0.9828519795351676 1.0 1.0 2 Q5JTZ9 1 +MIT domain [IPR007330] 0.3796477495107536 0.0204458797784283 0.9836876847177456 1.0 1.0 2 O75351 1 +Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.3796477495107536 0.0204458797784283 0.9836876847177456 1.0 1.0 2 O75351 1 +CELF1/2, RNA recognition motif 3 [IPR034199] 0.3623613829093199 0.019799980310534 0.984202933591034 1.0 1.0 2 Q92879 1 +CELF1/2, RNA recognition motif 2 [IPR034198] 0.3623613829093199 0.019799980310534 0.984202933591034 1.0 1.0 2 Q92879 1 +CELF1/2, RNA recognition motif 1 [IPR034196] 0.3623613829093199 0.019799980310534 0.984202933591034 1.0 1.0 2 Q92879 1 +GCF, C-terminal [IPR022783] 0.3532289628179983 0.0195591254760011 0.9843950707349378 1.0 1.0 2 P16383 1 +FF domain [IPR002713] 0.3499673842139491 0.0194866335507903 0.9844528999011976 1.0 1.0 2 O75400 1 +2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041] 0.3470319634703133 0.0194268083157651 0.9845006244983016 1.0 1.0 2 P21912 1 +ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661] 0.338551859099801 0.0192797258515078 0.984617957350086 1.0 1.0 2 Q9NRM2 1 +3'-5' exonuclease domain [IPR002562] 0.313437703848659 0.0190124797023804 0.9848311498468598 1.0 1.0 2 Q9NVH0 1 +Histone H2A, C-terminal domain [IPR032454] 0.3197389885807534 0.0174178741753739 0.9861032497884497 1.0 1.0 3 P16104,O75367 2 +Nop domain [IPR002687] 0.3171288743882533 0.0165686179045308 0.986780760405191 1.0 1.0 3 Q8WWY3,Q9Y2X3 2 +NOSIC [IPR012976] 0.3171288743882533 0.0165686179045308 0.986780760405191 1.0 1.0 3 Q8WWY3,Q9Y2X3 2 +Kinesin motor domain [IPR001752] 0.2652927706902255 0.0162216896263958 0.987057531919894 1.0 1.0 11 Q14807,O95239,Q99661,Q8NI77,P33176,Q86Y91,P52732,Q12756,O00139,Q9Y496 10 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.2808107224583194 0.0161834543794102 0.9870880352289624 1.0 1.0 9 P50570,Q9H223,O60313,O00429,Q8IWA4,O95140,Q05193,Q9H4M9 8 +Dynamin, N-terminal [IPR045063] 0.2808107224583194 0.0161834543794102 0.9870880352289624 1.0 1.0 9 P50570,Q9H223,O60313,O00429,Q8IWA4,O95140,Q05193,Q9H4M9 8 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8af42890f879c27a6d993f9742de08240be98c41 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain [IPR002073]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenomatous polyposis coli protein basic domain [IPR009234]", "Adenomatous polyposis coli, N-terminal dimerisation domain [IPR032038]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-dystroglycan N-terminal domain 2 [IPR041631]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-binding protein cabin-1, MEF2-binding domain [IPR015134]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbohydrate kinase, FGGY, N-terminal [IPR018484]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-glucuronyl C5-epimerase, C-terminal [IPR010598]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DG-type SEA domain [IPR030398]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "Dystroglycan, C-terminal [IPR008465]", "Dystroglycan-type cadherin-like [IPR006644]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB-1 binding [IPR009232]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephexin-1, SH3 domain [IPR035635]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin receptor-binding domain [IPR001799]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Ephrin-B ectodomain [IPR034255]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain [IPR002938]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FOXO protein, KIX-binding domain [IPR032068]", "FOXO protein, transactivation domain [IPR032067]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAT, C-terminal dimerisation domain [IPR008906]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxyacylglutathione hydrolase, C-terminal domain [IPR032282]", "Hydroxyacylglutathione hydrolase, MBL domain [IPR035680]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Initiation factor eIF2 gamma, C-terminal [IPR015256]", "Initiation factor eIF2 gamma, GTP-binding domain [IPR044128]", "Initiation factor eIF2 gamma, domain 2 [IPR044127]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-specific demethylase 4, Tudor domain [IPR040477]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTF2, PHD domain 1 [IPR042014]", "MTF2, PHD domain 2 [IPR042015]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nas2, N-terminal [IPR040815]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAS domain [IPR000014]", "PAS fold [IPR013767]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Par3/HAL, N-terminal [IPR021922]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb-like MTF2 factor 2, C-terminal domain [IPR025894]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Putative zinc-finger domain [IPR019607]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "Quinolinate phosphoribosyl transferase, C-terminal [IPR002638]", "Quinolinate phosphoribosyl transferase, N-terminal [IPR022412]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RFX1 transcription activation region [IPR007668]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad4 beta-hairpin domain 1 [IPR018326]", "Rad4 beta-hairpin domain 2 [IPR018327]", "Rad4 beta-hairpin domain 3 [IPR018328]", "Rad4/PNGase transglutaminase-like fold [IPR018325]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "RmlD-like substrate binding domain [IPR029903]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3PXD2, PX domain [IPR037961]", "SH3PXD2B, SH3 domain 1 [IPR035477]", "SH3PXD2B, SH3 domain 2 [IPR035478]", "SH3PXD2B, SH3 domain 3 [IPR035479]", "SH3PXD2B, SH3 domain 4 [IPR035480]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFA2, Winged helix domain 2 [IPR040501]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM4, PRY/SPRY domain [IPR035829]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIE beta subunit, DNA-binding domain [IPR003166]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UME domain [IPR012993]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps72/YL1, C-terminal [IPR013272]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, BED-type [IPR003656]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-like [IPR014857]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANK3", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APMAP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARMCX3", "ARMT1", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7B", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCKDHA", "BCKDK", "BCR", "BCS1L", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPHL", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C1orf35", "C2CD2", "C3orf58", "CABIN1", "CACYBP", "CAD", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COG4", "COIL", "COLEC12", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAG1", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCTN1", "DCUN1D1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FOXK1", "FOXO3", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E2", "GTF3C1", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "IVD", "IWS1", "JAM3", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIN", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSM12", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBLAC2", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "METAP1", "METTL13", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCL", "NCLN", "NCSTN", "ND5", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP3CA", "PPP4C", "PPP5C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RTCA", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPC25", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMM10", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TKT", "TLK2", "TLN1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13D", "VPS18", "VPS29", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WIZ", "WNK1", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YBX3", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZYX"], "leading_proteins": ["AARS2", "ABCB1", "ABCC4", "ACBD3", "ACOX1", "ACSL6", "ACTN4", "AGAP3", "AKAP8", "ALDH1A2", "ALG11", "ALYREF", "ANKLE2", "ANP32B", "ARMT1", "ASH2L", "ATAD3B", "ATP13A1", "ATP2A2", "ATP7B", "BCR", "BRD4", "CALU", "CASK", "CBX3", "CBX5", "CELF1", "CENPB", "CHD3", "CIRBP", "CIZ1", "CLPB", "CPSF3", "CPSF7", "CTPS1", "CYB5B", "CYB5D2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB12", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNM1", "DNM1L", "DNM2", "DUSP9", "EHD1", "EHD4", "EIF4B", "ELAVL1", "EPS15", "ERGIC3", "ERI1", "ERLIN1", "ESYT2", "EWSR1", "EXD2", "EXOSC2", "EXOSC5", "EXOSC7", "FCGRT", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FLOT2", "FOXK1", "FOXRED1", "FUBP1", "FUBP3", "FUS", "GAK", "GALNT1", "GALNT7", "GCFC2", "GNG12", "GPKOW", "GRHPR", "H1F0", "H2AFX", "H2AFY", "H3-3A*", "H4C1*", "HDGF", "HDGFL2", "HGS", "HIST1H1D", "HIST1H1E", "HLA-A", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HNRNPUL1", "IDH2", "IGF2BP2", "IGF2R", "IMP4", "INA", "JAM3", "KDM1B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KMT2A", "KRR1", "LARP4B", "LEMD3", "LGALS3BP", "LMNA", "LMNB1", "LMNB2", "LPP", "LYRM7", "MAK16", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "METTL13", "MFN1", "MFN2", "MICU1", "MICU2", "MID1", "MPP2", "MPP6", "MRPL15", "MTHFD1", "MTHFD2", "MTX1", "MTX3", "MYH10", "MYH9", "NCL", "NEFM", "NENF", "NGEF", "NKRF", "NOLC1", "NONO", "NOP58", "NPEPPS", "NUCB1", "NUCB2", "OCLN", "OPA1", "P3H1", "P4HA1", "PABPC4", "PABPN1", "PARN", "PDLIM5", "PELO", "PGRMC2", "PHB2", "PHGDH", "PIAS2", "PIK3R2", "PLOD2", "PLOD3", "PMPCA", "POMGNT2", "PPAN", "PRKCA", "PRKCB", "PRKRA", "PROCR", "PRPF31", "PRPF40A", "PSME1", "PSME2", "PSPC1", "PTBP2", "PTGR2", "PTPRF", "QKI", "RACGAP1", "RALY", "RANBP9", "RAVER1", "RBM10", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM3", "RBM4", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCN1", "RCN2", "RHOT2", "RNF213", "RNF40", "RPF1", "RPF2", "RPS10", "RTN3", "S100A11", "SARNP", "SCAF4", "SDHB", "SF3A2", "SF3A3", "SFPQ", "SKIV2L", "SLC18B1", "SLC27A2", "SLC4A1AP", "SLTM", "SMARCA1", "SMARCC2", "SMARCD2", "SMARCE1", "SNAP29", "SNRNP70", "SNRPA", "SNRPA1", "SPNS1", "SRRM2", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF7", "SRSF9", "STAG1", "STAM", "STAU1", "STIP1", "STOML2", "STX12", "STX17", "SUGP1", "SYNCRIP", "TAF15", "TBC1D9B", "TBCB", "TBCE", "TIA1", "TIMM50", "TMED10", "TMED4", "TMED9", "TRA2A", "TRA2B", "TRAM1", "TRIM21", "TRIM4", "UBQLN4", "UBTF", "UQCRC2", "VIM", "VPS4B", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2", "ZC3H18", "ZFR", "ZNF277", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cf1055ec529245b750ed79c477a9951fd7878bb0 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Proteasome B-type subunit [IPR023333]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..123e916d39a6938a29f32b812619f28da9e98960 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b7801af94da734cb32cd721494edd3160a71110a65f0532684d23ca5fef5c3b +size 193274 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b24a8d9683523e728b84dd358c60b679ba25b3b3 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:532970106a0b1c3651dc530810bd97957b140a3fb9fd03bda100912224c15003 +size 184925 diff --git 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8dd004b8fcfe62c5e37dfe0dbd388babc3f2825629d5d9734f6f11472566290 +size 160535 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..331b81126445366ae80b5b781e8b6132e928a5fe --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bde52dbbc02d00e8969c284fea4d8fbda01692e51c14c3584dceafa5a20dc57c +size 144453 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7d562b39de674cbb31f366cd1e88fcbe3e44b5c2 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4cf2d8b7bcc36355ffcd7906610f66bd16d9877c68542007c4a850e65f3c1165 +size 261636 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..617b31cb984f5b13cf39ba1fb132258b61de6388 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome, subunit alpha/beta [IPR001353] 5 14 2.4296155203041563 0.0151148473002769 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 0.0078149165881974 0.0026008925831016 0.0100519320580488 2.7582058036655703e-05 6.703246650942136e-05 +Proteasome B-type subunit [IPR023333] 5 7 2.3524658544521477 0.0186494019243264 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0024360578362321 0.0007972103198291 0.0031504918831051 9.14133433735114e-07 9.4206715064497e-07 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fed5a635a0fce06886cd7ad178cd28ef48606f76 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 2394, + "title": "Average number of proteins per term", + "value": 1.2882205513784462 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f92f8a0d48894077b1ba8c7397112e4dfe1f9d4d --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..39a5747a438b7f45d810fba9af5783759ff4d93a --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,100 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome, subunit alpha/beta [IPR001353] 0.7155263362708982 2.4296155203041563 0.0151148473002769 1.0 0.2403959369343067 14 P28070,P28072,P49721,P20618,Q99436 5 +Proteasome B-type subunit [IPR023333] 0.8629869160646 2.3524658544521473 0.0186494019243264 1.0 0.2403959369343067 7 P28070,P28072,P49721,P20618,Q99436 5 +Eukaryotic porin/Tom40 [IPR027246] 0.9058308968168788 2.025236345081802 0.0428431012952708 1.0 0.2459625527599 4 P21796 1 +Aminopeptidase N-type [IPR034016] 0.8854130530681732 1.946801813027099 0.0515584995294844 1.0 0.2559211654559999 4 P55786 1 +Porin, eukaryotic type [IPR001925] 0.9351645766043768 1.7120146719515097 0.0868939646510482 1.0 0.3126498219697364 3 P21796 1 +Annexin [IPR001464] 0.7461552737983435 1.6912421852282606 0.0907905570565641 1.0 0.318509826273603 6 P50995,P09525,P20073,P08133 4 +Linker histone H1/H5 [IPR005819] 0.7465928659900228 1.685149618711124 0.0919597085088816 1.0 0.3201213040367355 5 P07305,P16402,P10412 3 +Glutathione Transferase family [IPR040079] 0.6190524598937005 1.6733129540009894 0.0942657036329279 1.0 0.3222325196397165 11 Q13505,Q5HYI7 2 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.738290581702346 1.657781389030862 0.0973615990989702 1.0 0.3290926773506999 6 P55786 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.9109298531810728 1.6222512556449074 0.1047495610265252 1.0 0.3377528727994796 3 P55209,Q99733 2 +Type 1 protein exporter [IPR039421] 0.798793354103885 1.6080682740592205 0.1078202266815764 1.0 0.3427909995693147 4 P08183 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.9008156606851504 1.5846672501749983 0.1130419565353821 1.0 0.3487402628166301 3 P28072,Q99436 2 +P-type ATPase [IPR001757] 0.7108934661618375 1.5335016838198678 0.1251522920926053 1.0 0.369260612826268 5 Q9HD20,P35670 2 +Nonaspanin (TM9SF) [IPR004240] 0.8807961374549202 1.5100995573767313 0.1310180224395161 1.0 0.3760877047004815 3 Q99805 1 +KH domain-containing BBP-like [IPR045071] 0.7698432255528997 1.4930602621602052 0.1354214132083475 1.0 0.3805957778790714 4 O75525,Q96PU8 2 +TAF15/EWS/TLS family [IPR034870] 0.8643415016898554 1.4486708034755398 0.1474295377824188 1.0 0.3985105304822807 3 Q92804 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.6897056392255467 1.4428221850217484 0.1490705679735413 1.0 0.4005063960946243 5 Q7Z7H5,P49755,Q9BVK6 3 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.8313213703099388 1.3251908329560749 0.1851078650571973 1.0 0.4517311202313256 3 Q9HB40,Q9H3G5 2 +Major facilitator superfamily [IPR011701] 0.6577201835638424 1.3052640261749895 0.1918029590995562 1.0 0.4590951912925418 5 Q6NT16,Q9H2V7 2 +HnRNP-L/PTB [IPR006536] 0.7159972438904492 1.2777515297213484 0.201337049717255 1.0 0.4702447775835206 4 Q9UKA9 1 +14-3-3 protein [IPR000308] 0.6495754408883098 1.2752669648096986 0.2022147662777094 1.0 0.4709757522261202 6 P63104,P62258,P31946,P61981,Q04917 5 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.810766721044034 1.2483248207958904 0.2119121280865936 1.0 0.4867422632196209 3 O43823,Q5BKZ1 2 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9993476842791912 1.170119223232487 0.2419529935303241 1.0 0.5218337536140506 2 Q99595 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.989889106327462 1.1377073878482555 0.2552426874805604 1.0 0.5360096437091769 2 Q5VW38 1 +Nucleobindin [IPR040250] 0.9722765818656208 1.0776348692340538 0.2811967347478075 1.0 0.5653510278983871 2 P80303 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.94487932159165 0.9850931734651038 0.32457830625562 1.0 0.6078415041440997 2 Q15067 1 +Acyl-CoA oxidase [IPR012258] 0.94487932159165 0.9850931734651038 0.32457830625562 1.0 0.6078415041440997 2 Q15067 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9403131115459852 0.969797566201638 0.3321474062345304 1.0 0.6164037911050122 2 P48735 1 +Protein kinase C, alpha/beta/gamma types [IPR014375] 0.9399869536855836 0.9687065822293258 0.3326916074977397 1.0 0.616935482842439 2 P17252 1 +Mpv17/PMP22 [IPR007248] 0.7252298361587952 0.9315684857320684 0.3515595759499514 1.0 0.6305886926453358 3 Q567V2 1 +HnRNP R/Q splicing factor [IPR006535] 0.9256360078277874 0.920922519218299 0.3570908805467501 1.0 0.6360681309738986 2 O60506 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.9249836921069796 0.9187612116552906 0.3582204849439854 1.0 0.6365929994113635 2 Q8IYU8 1 +Small GTPase superfamily, ARF type [IPR024156] 0.6104934640608877 0.8586427058545559 0.3905376691811413 1.0 0.6687307255063832 4 P18085,Q96KC2 2 +Prefoldin beta-like [IPR002777] 0.6892935635039199 0.8021149209143309 0.4224864846543217 1.0 0.7009235233973985 3 O15212 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8874755381604692 0.7963229431219163 0.4258443535403928 1.0 0.7027777537734267 2 O96005 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8874755381604692 0.7963229431219163 0.4258443535403928 1.0 0.7027777537734267 2 O96005 1 +Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311] 0.8688845401174139 0.7372085570950752 0.4609955304601318 1.0 0.7327738059724948 2 Q9UKU0 1 +CD36 family [IPR002159] 0.8682322243965983 0.7351562954275604 0.4622443125173125 1.0 0.7333418715483409 2 Q8WTV0 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.861709067188513 0.7147208663046025 0.4747815414774017 1.0 0.7445690928893919 2 Q96N66 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.856490541422043 0.6984901772843068 0.4848706986886495 1.0 0.749098228407143 2 P07910 1 +Cohesin subunit Scc3/SA [IPR039662] 0.8561643835616419 0.6974793339210389 0.4855028681798916 1.0 0.749098228407143 2 Q8WVM7 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8512720156555766 0.6823684172093579 0.4950060210869398 1.0 0.7557681214809527 2 Q00765 1 +Tropomyosin [IPR000533] 0.8502935420743621 0.6793580449212202 0.4969110264617042 1.0 0.7566688635435993 2 P06753 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.8101761252446064 0.5596997925039873 0.5756842239128965 1.0 0.8154958769511682 2 Q93050 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.8101761252446064 0.5596997925039873 0.5756842239128965 1.0 0.8154958769511682 2 Q93050 1 +G-protein, gamma subunit [IPR001770] 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 0.847662242898175 2 Q9UBI6 1 +THRAP3/BCLAF1 family [IPR029199] 0.7857142857142813 0.4908850945120091 0.623507719937284 1.0 0.8484030067527482 2 Q9Y2W1 1 +Syntaxin [IPR045242] 0.4436558111617794 0.4855985249859225 0.6272518424511269 1.0 0.8496729536685342 7 P56962,Q86Y82 2 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.7831050228310368 0.4837557368563144 0.6285592318074245 1.0 0.8496729536685342 2 Q9Y282 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.7778864970645771 0.4696261687146495 0.6386221250286659 1.0 0.8569850713669429 2 Q5T9A4 1 +Prolyl 4-hydroxylase [IPR045054] 0.7720156555772923 0.4539410998973208 0.6498712207946993 1.0 0.8630258897171741 2 P13674 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.7544031311154495 0.4082888305448245 0.6830616385189194 1.0 0.8775589516875344 2 Q8TCJ2 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4260225042391111 0.3644638606378006 0.715511655736131 1.0 0.8935497672573279 5 Q14344,P04899 2 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.7217873450750141 0.3297889498697675 0.7415594374348644 1.0 0.9029257842174742 2 Q9Y3E5 1 +Tropomodulin [IPR004934] 0.7097195042400486 0.3028995757825234 0.7619663946534423 1.0 0.9099090954674334 2 Q9NYL9 1 +Pyridoxal phosphate-dependent decarboxylase [IPR002129] 0.7067840834964013 0.2965445277442094 0.7668142670391578 1.0 0.9099090954674334 2 O95470 1 +Sorting nexin-5/6/32 [IPR014637] 0.7045009784735772 0.2916527789765967 0.770552117070993 1.0 0.9099090954674334 2 Q9Y5X3 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.7015655577299382 0.2854295366010524 0.7753150813462131 1.0 0.9109252325202588 2 Q9Y5J9 1 +Tumour protein D52 [IPR007327] 0.6813437703848579 0.2446236043093587 0.806747885651121 1.0 0.9173715672151672 2 P55327 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.3116485949652431 0.2401365504593567 0.8102243998856216 1.0 0.9173715672151672 21 Q9BY49,Q6YN16,Q06136,Q9HBH5,Q8NBQ5,Q9Y394 6 +Mitochondrial Rho GTPase [IPR021181] 0.6598173515981619 0.2052701786429463 0.8373610419403112 1.0 0.9225352243851704 2 Q8IXI1 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6581865622961438 0.2024644175711087 0.8395536730099569 1.0 0.9225352243851704 2 O75150 1 +Tricarboxylate/iron carrier [IPR004686] 0.4847218017936465 0.1988418065381399 0.8423864920201707 1.0 0.9225403759818338 3 Q96NB2 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.6373124592302591 0.1687627029587086 0.8659832961922405 1.0 0.9326490708391396 2 Q13310 1 +Ribosomal protein S17/S11 [IPR000266] 0.6298108284409578 0.1576564515714021 0.874727517843541 1.0 0.9365212096839454 2 Q9Y2R5 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.6138290932811377 0.1357613931408227 0.8920099122276886 1.0 0.943006578251885 2 P18085 1 +Chaperone DnaJ [IPR012724] 0.4486133768352246 0.1332258424437858 0.8940147737028006 1.0 0.943006578251885 3 Q96EY1,P31689 2 +Proteasome activator PA28 [IPR009077] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 0.9465505471460688 3 Q06323,Q9UL46 2 +Prohibitin [IPR000163] 0.5994781474233428 0.1181242356025057 0.905969220652155 1.0 0.9487709161160364 2 Q99623 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.4378466557911823 0.1166977878233357 0.907099543360146 1.0 0.9495392683883644 3 Q92688,P39687 2 +Dynein light chain, type 1/2 [IPR001372] 0.5942596216568687 0.112177045635449 0.9106830292073552 1.0 0.9524574800884268 2 P63167 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.4342577487765057 0.1114981918256724 0.9112212993747776 1.0 0.952604275416252 3 Q9BZJ0,Q9HCS7 2 +Nuclear pore complex protein [IPR026054] 0.4287112561174366 0.1037650977230059 0.9173557648886992 1.0 0.9569279743544862 3 A8CG34,P49790 2 +G-protein alpha subunit, group I [IPR001408] 0.4172920065252799 0.0889890573880633 0.9290906065559644 1.0 0.967729812436791 3 P04899,P09471 2 +CTP synthase [IPR004468] 0.571102413568152 0.0886905590512124 0.9293278357527914 1.0 0.967729812436791 2 P17812 1 +Ribonuclease CAF1 [IPR006941] 0.4104404567699775 0.0808514203304504 0.9355601143769128 1.0 0.9725275353097392 3 Q96GM8,O95453 2 +La domain containing protein [IPR045180] 0.3076310839876908 0.068869516326528 0.945093483335398 1.0 0.979884711608897 5 Q92615 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.3351827676240267 0.0661972492599685 0.9472207867455008 1.0 0.9808753399870656 4 Q96BP3,Q9H2H8,Q13356 3 +Purine 5'-nucleotidase [IPR016695] 0.382055464926577 0.0526881762947552 0.9579803598908204 1.0 0.9891562894220584 3 Q9H857,P49902 2 +Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672] 0.3771615008156614 0.0486883273329879 0.9611676782830184 1.0 0.9906638587342632 3 P13995,P11586 2 +Nucleolar, Nop52 [IPR010301] 0.5117416829745399 0.0479356640904665 0.9617675162153936 1.0 0.9906638587342632 2 P56182 1 +Mini-chromosome maintenance protein [IPR031327] 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 0.9922811769572976 6 P25205,P33991,Q14566,P33993,P49736 5 +Phosphatidylethanolamine-binding protein [IPR008914] 0.4918460534898755 0.0394916341361339 0.9684984233076124 1.0 0.9922811769572976 2 P30086 1 +Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810] 0.4918460534898755 0.0394916341361339 0.9684984233076124 1.0 0.9922811769572976 2 P30086 1 +Stomatin/HflK/HflC family [IPR001972] 0.482061317677739 0.0361092169998902 0.971195273018974 1.0 0.9931830344329022 2 Q9UJZ1 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.4797782126549132 0.0353863814854866 0.9717716439120307 1.0 0.993348127892998 2 Q15477 1 +Tight junction protein ZO [IPR005417] 0.4742335290280394 0.0337297559649291 0.9730926506385676 1.0 0.99427392472417 2 Q07157 1 +NudC family [IPR037898] 0.4533594259621575 0.0286320944523635 0.9771580149001496 1.0 0.9951524875784108 2 Q9Y266 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4484670580560895 0.0276693749050214 0.9779258496327944 1.0 0.9951524875784108 2 P31689 1 +Vacuolar protein sorting protein 26 related [IPR028934] 0.4478147423352667 0.0275470058617998 0.9780234488003148 1.0 0.9951524875784108 2 Q4G0F5 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.3350734094616673 0.0232778120807002 0.9814286703127432 1.0 0.9951524875784108 3 Q9H2H8,O43447 2 +Alanine-tRNA ligase, class IIc [IPR002318] 0.3979125896934066 0.0214935112574544 0.9828519795351676 1.0 0.9951524875784108 2 Q5JTZ9 1 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.3979125896934066 0.0214935112574544 0.9828519795351676 1.0 0.9951524875784108 2 Q5JTZ9 1 +Vinculin/alpha-catenin [IPR006077] 0.3894324853228875 0.0209521495825599 0.9832838263873992 1.0 0.9951524875784108 2 P35221 1 +Ras-related protein Ral [IPR028412] 0.3868232224396543 0.0208055701381364 0.9834007543741324 1.0 0.9951524875784108 2 P11234 1 +Vacuolar protein sorting-associated protein 4 [IPR031255] 0.3796477495107536 0.0204458797784283 0.9836876847177456 1.0 0.9951524875784108 2 O75351 1 +Ribosomal protein L15 [IPR030878] 0.3724722765818624 0.0201434196600105 0.9839289632824136 1.0 0.9951524875784108 2 Q9P015 1 +26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134] 0.2879973907371117 0.0188960987768777 0.98492399171152 1.0 0.9952588689558614 2 Q9BT78 1 +Histone H2A [IPR002119] 0.3197389885807534 0.0174178741753739 0.9861032497884497 1.0 0.9952588689558614 3 P16104,O75367 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2b98906bac78ab4e118787f948e1e918ab5c0ad4 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome non-ATPase regulatory subunit 9 [IPR035269]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3'5'-cyclic nucleotide phosphodiesterase [IPR023088]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abr/Bcr [IPR037769]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenomatous polyposis coli (APC) family [IPR026818]", "Adenomatous polyposis coli [IPR026836]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 2 [IPR005293]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [IPR013109]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD34/Podocalyxin [IPR013836]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC50/LEM3 family [IPR005045]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centromere protein P [IPR027801]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "D-glucuronyl C5-epimerase [IPR039721]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad4 [IPR004583]", "DNA repair protein Rad4, subgroup [IPR018026]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dpy-19/Dpy-19-like [IPR018732]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1 [IPR027741]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dysbindin [IPR007531]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 SUMO-protein ligase PIAS2 [IPR027228]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ephrin [IPR031328]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Essential MCU regulator, mitochondrial [IPR018782]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fyv7/TAP26 [IPR013730]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gem-associated protein 4 [IPR033265]", "Geranylgeranyl transferase type-1 subunit beta [IPR041960]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucocorticoid receptor [IPR001409]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HIRA-interacting protein 3 [IPR037647]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone transcription regulator 3/CABIN1 [IPR033053]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxyacylglutathione hydrolase [IPR017782]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional adhesion molecule C [IPR042974]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipoma-preferred partner [IPR028771]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICAL3 [IPR029941]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med24, [IPR021429]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type D protein [IPR019362]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit TOM6 homologue [IPR029182]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial intermembrane space import and assembly protein 40 [IPR039289]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NURS complex subunit red1 [IPR039278]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neutral amino acid SLC6 transporter [IPR002438]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nicotinate-nucleotide pyrophosphorylase [IPR004393]", "Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD [IPR027277]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-structural maintenance of chromosomes element 1 [IPR011513]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor NF-kappa-B, p100 subunit [IPR030497]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear pore protein POM121 [IPR026090]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OCIA domain-containing protein 1/2 [IPR040187]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Optineurin [IPR032939]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Podocalyxin [IPR017403]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable C-mannosyltransferase DPY19L3 [IPR030039]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RFX-like DNA-binding protein [IPR039779]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA exonuclease 4 [IPR034920]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein Rsm22-like [IPR015324]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3 and PX domain-containing protein 2B [IPR030512]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sarcolemmal membrane-associated protein [IPR030498]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Schlafen family [IPR029684]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Sedoheptulokinase [IPR042027]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium/solute symporter [IPR001734]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntaxin-3 [IPR031186]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex subunit 7/Mft1 [IPR008501]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIA, alpha/beta subunit [IPR004855]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIIE, beta subunit [IPR016656]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 161A/B [IPR019395]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Twinfilin [IPR028458]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Type-1 angiotensin II receptor-associated protein [IPR009436]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiE/COQ5 methyltransferase [IPR004033]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat and coiled-coil-containing protein family [IPR028041]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger protein 277 [IPR040048]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUD31", "BYSL", "C12orf43", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C3orf58", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CABIN1", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CAST", "CBFB", "CBR1", "CBR4", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC37", "CDC42", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPB", "CENPF", "CENPI", "CENPP", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1L", "CHD8", "CHERP", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG6", "COG7", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF16", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPM1", "DPP3", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFNB1", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "F11R", "FADS2", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GCAT", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO4", "IPO5", "IRGQ", "IRS4", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LONP1", "LPP", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "NAA10", "NAA15", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCLN", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF3", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFCD", "NELFE", "NES", "NF1", "NFKB2", "NHP2", "NIF3L1", "NIP7", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRDE2", "NRM", "NSA2", "NSF", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POLA1", "POLA2", "POLD1", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOX1", "RIOX2", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", 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a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..62c9641a8c3c9ec898cd8751669bfeb16f7845b9 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69dc1d428d1396a639c9a016087edb8bba0edc333ca08939c623efbdd1e53422 +size 113538 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..63d56fc3d3b6a4c46e03cb70816867aa2b20929d --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 60 132 2.941252203869625 0.0032688826532178 41.78155339805825 126.65533980582524 0.1165973051667422 0.543214063567699 13.579176287791377 6.87987395678373 1.6323826073741117 0.3875195330163939 0.5110274723330215 1.0 0.3072324825572405 1.6326005329085642e-08 2.4644136226814564e-15 +RNA-binding domain superfamily [IPR035979] 62 133 2.8012677822141367 0.0050902261090257 42.40291262135922 128.71601941747574 0.0615554024640467 0.5527296641044032 14.098054374547743 6.713949807605091 1.6556654950344032 0.3906506493803742 0.8192994121833466 1.0 0.5763684861057579 6.98846930618967e-08 9.261736418274874e-15 +Mitochondrial carrier domain superfamily [IPR023395] 3 18 2.5891969090779567 0.0096200067660296 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0039499816510121 0.0142466262053111 0.005693097574516 0.0128293519549119 0.0353817250131281 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 4 6 2.406340589364151 0.0161132345597629 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0001206551353332 0.0014481500629001 0.0001778916397324 5.41373461507268e-06 0.0001575214550341 +Nucleophile aminohydrolases, N-terminal [IPR029055] 5 18 2.15515243645062 0.031149907517374 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 0.0186027181842145 0.0063255491406275 0.0237627189197599 0.0002808583984775 0.0010205277760807 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2691736dcd96473db03bfeb3d6f5587509e8a295 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 944, + "title": "Average number of proteins per term", + "value": 4.807203389830509 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d1a5d5b4446b87ed28137fed197210801cbea0b0 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b94a3eba564654f0fda974af12b8039b9115c3ed --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,103 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.5069541164463968 2.941252203869625 0.0032688826532178 0.9545380625745772 0.3941146730816961 132 Q9Y5S9,Q8N684,P84103,Q96PK6,Q08170,Q15717,O95104,P23588,Q9H501,P23246,P31942,Q93062,Q8WVV9,Q13242,Q15233,P52597,Q9P2N5,Q14103,P55795,Q13151,Q8NFH5,P08621,Q99729,Q86U42,Q9NW64,Q07955,O60506,Q92804,Q9UKM9,P51991,P52756,P22626,P09012,Q14011,Q92615,Q86V81,Q53F19,P31943,Q13595,O14979,Q01844,Q9BWF3,P31483,O75494,O43390,P49756,P35637,Q96I25,Q8IY67,Q16629,P98175,P62995,P07910,P98179,Q96E39,Q9Y6M1,Q9UKA9,Q96T37,P38159,P09651 60 +RNA-binding domain superfamily [IPR035979] 0.4963185064006375 2.8012677822141367 0.0050902261090257 0.9919125743872328 0.3941146730816961 133 Q9Y5S9,Q8N684,P84103,Q96PK6,Q08170,Q15717,P23588,Q71RC2,O95104,P23246,P31942,Q93062,Q8WVV9,Q8WXF1,Q13242,Q15233,P52597,Q9P2N5,Q14103,P55795,Q13151,Q8NFH5,P08621,Q99729,Q86U42,Q9NW64,Q9NWH9,O60506,Q92804,Q07955,Q9UKM9,P51991,P52756,P22626,Q9Y4C8,P09012,Q14011,Q92615,Q86V81,P31943,Q13595,O14979,Q01844,Q9BWF3,P31483,O75494,O43390,P49756,P35637,Q96I25,Q8IY67,Q16629,P98175,P62995,P07910,P98179,Q96E39,Q9Y6M1,Q9UKA9,Q96T37,P38159,P09651 62 +Mitochondrial carrier domain superfamily [IPR023395] 0.6763767725442996 2.5891969090779567 0.0096200067660296 0.9998911184085748 0.3941146730816961 18 Q9UBX3,O43772,Q70HW3 3 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.9205279894643852 2.406340589364151 0.0161132345597629 0.99999978112703 0.3941146730816961 6 Q8WUJ1,O15173,Q9UMX5,O43169 4 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.6051048802247676 2.15515243645062 0.031149907517374 0.9999999999998938 0.4071795201759648 18 P28070,P28072,P49721,P20618,Q99436 5 +Porin domain superfamily [IPR023614] 0.9058308968168788 2.025236345081802 0.0428431012952708 1.0 0.4071795201759648 4 P21796 1 +EF-hand domain pair [IPR011992] 0.5551199938299417 1.8853142923952575 0.0593874176586699 1.0 0.4391253765902349 46 Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q66K14,Q96AY3,Q02818,Q9NWM8,Q9Y680,O43852 11 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.7517033645111342 1.8732101556787408 0.0610393704862177 1.0 0.4432397364537659 7 P22695,Q10713 2 +L27 domain superfamily [IPR036892] 0.7860478571363222 1.8507089629812592 0.0642114339246266 1.0 0.4557563430439668 5 Q9NZW5,Q14168,O14936 3 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8565520757702432 1.8349642803269737 0.0665109821674869 1.0 0.4616644644566742 4 P42892 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.7024861316993796 1.820806756864724 0.0686362368396562 1.0 0.4661338674578094 8 P98175,P35637,Q92804 3 +LEM/LEM-like domain superfamily [IPR011015] 0.7719377394737437 1.8002788565136632 0.0718166177434109 1.0 0.4690228518074004 6 Q86XL3 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7680597632506372 1.7839450884098604 0.0744325883544183 1.0 0.4715729087689324 6 O15439,P08183 2 +MFS transporter superfamily [IPR036259] 0.6299981962303554 1.7307729313944369 0.0834922715502952 1.0 0.4895447474750232 11 Q99808,P41440,Q9H2V7,Q6NT16,P53985,Q6N075 6 +Annexin superfamily [IPR037104] 0.7461552737983435 1.6912421852282606 0.0907905570565641 1.0 0.4897502049222659 6 P50995,P09525,P20073,P08133 4 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.738290581702346 1.657781389030862 0.0973615990989702 1.0 0.5005902085931592 6 P55786 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.738290581702346 1.657781389030862 0.0973615990989702 1.0 0.5005902085931592 6 P55786 1 +NAP-like superfamily [IPR037231] 0.9109298531810728 1.6222512556449074 0.1047495610265252 1.0 0.5044025567292945 3 P55209,Q99733 2 +HAD superfamily [IPR023214] 0.5136818482631886 1.5554637220430003 0.1198356681367043 1.0 0.5297737369540247 19 Q969T7,Q9HD20,Q5TFE4 3 +HAD-like superfamily [IPR036412] 0.5136818482631886 1.5554637220430003 0.1198356681367043 1.0 0.5297737369540247 19 Q969T7,Q9HD20,Q5TFE4 3 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7108934661618375 1.5335016838198678 0.1251522920926053 1.0 0.5297737369540247 5 Q9HD20,P35670 2 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7108934661618375 1.5335016838198678 0.1251522920926053 1.0 0.5297737369540247 5 Q9HD20,P35670 2 +P-type ATPase, A domain superfamily [IPR008250] 0.7108934661618375 1.5335016838198678 0.1251522920926053 1.0 0.5297737369540247 5 Q9HD20,P35670 2 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.5039587872288438 1.5050510941380075 0.132310941119615 1.0 0.5418909483383046 18 Q13505,Q5HYI7 2 +Lamin tail domain superfamily [IPR036415] 0.8769983686786278 1.4959312569045973 0.1346715699971783 1.0 0.5456221548383534 3 P02545,Q03252 2 +Fibronectin type III superfamily [IPR036116] 0.6803054978811593 1.4086168810632904 0.1589484844904087 1.0 0.588280335354318 6 Q8NAT1,P10586 2 +Prefoldin [IPR009053] 0.6798491978280823 1.4066417372085418 0.1595336502655777 1.0 0.588280335354318 6 O15212,Q9UBK9 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.6537523220619221 1.2881632990998362 0.1976891246222387 1.0 0.6380645166620674 5 P04439,Q9UNN8 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.6537523220619221 1.2881632990998362 0.1976891246222387 1.0 0.6380645166620674 5 P04439,Q9UNN8 2 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.6523818235379769 1.282255606925351 0.1997529952931929 1.0 0.6406535650988465 5 Q9HDC9 1 +14-3-3 domain superfamily [IPR036815] 0.6495754408883098 1.2752669648096986 0.2022147662777094 1.0 0.6406535650988465 6 P63104,P62258,P31946,P61981,Q04917 5 +K Homology domain, type 1 superfamily [IPR036612] 0.4804576547125077 1.264986399912002 0.2058762031661396 1.0 0.6456715474712154 25 Q96AE4,P61978,Q13868,Q92945,Q9Y6M1,Q96I24,O75525 7 +ANL, N-terminal domain [IPR042099] 0.6081492836668299 1.2221534894584771 0.221649588592818 1.0 0.6587301125957776 7 Q9UKU0,O14975 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4654055190895697 1.206595409142978 0.2275879956276274 1.0 0.668527569519364 21 O95831,Q8NB78,Q16134,Q9UHG3,Q6NUM9,Q96CU9 6 +ARFGAP/RecO-like zinc finger [IPR037278] 0.7976220054302405 1.199231471652629 0.2304379530640592 1.0 0.6695590906931419 3 Q96P47 1 +ArfGAP domain superfamily [IPR038508] 0.7976220054302405 1.199231471652629 0.2304379530640592 1.0 0.6695590906931419 3 Q96P47 1 +Ribokinase-like [IPR029056] 0.7671652576389834 1.0858869449490591 0.2775290134452248 1.0 0.7359196311581243 3 P55263 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.6606857877257211 1.0565474678362516 0.2907181662718916 1.0 0.7591656612243602 4 Q16629 1 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.5072818371965085 0.933879026742028 0.3503662986965719 1.0 0.8268644649239096 9 O94788 1 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.5072818371965085 0.933879026742028 0.3503662986965719 1.0 0.8268644649239096 9 O94788 1 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.5072818371965085 0.933879026742028 0.3503662986965719 1.0 0.8268644649239096 9 O94788 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.7123530471103202 0.8848135088190755 0.376257222343753 1.0 0.8580361014185666 3 P11717 1 +Alpha/Beta hydrolase fold [IPR029058] 0.4257973646304696 0.879609276909922 0.3790710115574751 1.0 0.8580361014185666 26 P34913,Q4J6C6,P07099,Q9NUJ1,P42785,Q9HB40,Q9UMR5,Q8NCC3 8 +Cupredoxin [IPR008972] 0.9129158512720084 0.8789593751986229 0.3794233031844827 1.0 0.8580361014185666 2 P00403 1 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.4808769680560074 0.8640304741955861 0.3875711501062535 1.0 0.8637411274731606 10 Q15067 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.4808769680560074 0.8640304741955861 0.3875711501062535 1.0 0.8637411274731606 10 Q15067 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.6882385827615429 0.7983677939734528 0.4246570870248267 1.0 0.887635547067509 3 Q08380 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3032741947671847 0.759899953277627 0.4473143895579212 1.0 0.903109013536464 80 Q9Y262,Q9NYH9,O43765,Q96EK5,Q99615,Q7L5D6,Q9Y6X3,P13674,Q96TC7,Q9UJX4,O75153,Q96DB5,Q32P28,O75718,Q6DKK2,Q92791,Q96BR5,Q13217,Q9NSK0 19 +GOLD domain superfamily [IPR036598] 0.6771521170630613 0.7592086145476441 0.4477277736600267 1.0 0.903109013536464 3 Q9H3P7 1 +Homeobox-like domain superfamily [IPR009057] 0.3819362410016854 0.6821476332724529 0.4951456035000769 1.0 0.932968961485175 19 Q8NB78,P07199,Q96G23 3 +Zinc finger, CCCH-type superfamily [IPR036855] 0.4851934432810106 0.5802832027757777 0.5617236528917762 1.0 0.9856266325833396 5 Q86VM9 1 +GroES-like superfamily [IPR011032] 0.416075415642257 0.5400135631649337 0.5891876788187986 1.0 0.9942054899533872 10 Q8N8N7,Q99536,Q8N4Q0 3 +SNARE [IPR010989] 0.4676255637028345 0.507594568267532 0.6117377006724947 1.0 1.0 6 P56962,Q86Y82 2 +G-protein gamma-like domain superfamily [IPR036284] 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Immunoglobulin E-set [IPR014756] 0.378710766205698 0.4882133742446356 0.6253987123069962 1.0 1.0 13 A6NIH7 1 +Ricin B-like lectins [IPR035992] 0.5885438286746305 0.4662617512346461 0.6410281532350257 1.0 1.0 3 Q10472 1 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 0.4381348992050725 0.405909333332081 0.6848092200143803 1.0 1.0 5 Q15024,Q9NQT4 2 +PNPase/RNase PH domain superfamily [IPR027408] 0.4381348992050725 0.405909333332081 0.6848092200143803 1.0 1.0 5 Q15024,Q9NQT4 2 +B30.2/SPRY domain superfamily [IPR043136] 0.3767909489909189 0.4051474514140163 0.6853691286216719 1.0 1.0 11 P19474,O15344,Q9BUJ2,Q96S59,Q9C037,Q9UBL3 6 +SMAD/FHA domain superfamily [IPR008984] 0.3834632891196147 0.3895850238687242 0.6968434280794431 1.0 1.0 10 Q9BWU0,P85037 2 +HIV integrase-binding domain superfamily [IPR036218] 0.7393998695368409 0.371160180101673 0.7105182298111636 1.0 1.0 2 Q7Z4V5 1 +Rho GTPase activation protein [IPR008936] 0.3791843353651579 0.3708065549610095 0.7107816187358105 1.0 1.0 10 Q9H0H5,Q14C86,O15031 3 +G protein alpha subunit, helical insertion [IPR011025] 0.4260225042391111 0.3644638606378006 0.715511655736131 1.0 1.0 5 Q14344,P04899 2 +AF1104-like superfamily [IPR036075] 0.7351598173515954 0.3609764409165053 0.7181170587766366 1.0 1.0 2 Q9H993 1 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.7217873450750141 0.3297889498697675 0.7415594374348644 1.0 1.0 2 Q9Y3E5 1 +Chaperone J-domain superfamily [IPR036869] 0.3302137747223827 0.3199660265450861 0.7489940846463301 1.0 1.0 16 Q96EY1,Q8IXB1,Q13217,Q99615,Q99543,O14976,P31689,Q9NXW2 8 +Protein-tyrosine phosphatase-like [IPR029021] 0.3770803767418603 0.2874751454225736 0.7737485302124938 1.0 1.0 8 Q99956 1 +Band 7/SPFH domain superfamily [IPR036013] 0.3769186186596123 0.2868503349822348 0.7742269199358014 1.0 1.0 8 Q99623,O75477,Q14254,Q9UJZ1 4 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.3249597630216838 0.2522957603452371 0.8008124649219985 1.0 1.0 14 Q86XL3,Q96P47 2 +HSP40/DnaJ peptide-binding [IPR008971] 0.4285248041775473 0.2433547760753636 0.8077305742907677 1.0 1.0 4 P31689,Q96EY1,O60884 3 +CAP Gly-rich domain superfamily [IPR036859] 0.4998368678629624 0.2308759672278004 0.817411161751616 1.0 1.0 3 Q99426,Q15813 2 +NAD(P)-binding domain superfamily [IPR036291] 0.2891252605475017 0.1359953386233745 0.89182496596931 1.0 1.0 70 Q13423,Q9BY49,Q99536,Q06136,Q16836,Q8N4Q0,Q8NBX0,Q8N8N7,O43865 9 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.4486133768352246 0.1332258424437858 0.8940147737028006 1.0 1.0 3 Q96EY1,P31689 2 +Proteasome activator superfamily [IPR036252] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 1.0 3 Q06323,Q9UL46 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 1.0 3 Q06323,Q9UL46 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.443066884176176 0.1245369341220863 0.9008901587888444 1.0 1.0 3 Q06323,Q9UL46 2 +SWIB/MDM2 domain superfamily [IPR036885] 0.6043705153294071 0.1239242844169211 0.901375224970654 1.0 1.0 2 Q92925 1 +Dynein light chain superfamily [IPR037177] 0.5942596216568687 0.112177045635449 0.9106830292073552 1.0 1.0 2 P63167 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.3175637715951801 0.109944320958389 0.9124535325356768 1.0 1.0 9 O60502,Q86UY6 2 +Nucleotidyltransferase superfamily [IPR043519] 0.340115315587513 0.1099419850525207 0.9124553850886384 1.0 1.0 6 Q96KR1 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.4107667210440451 0.0812267287797526 0.9352616432517378 1.0 1.0 3 P11274,Q8N5V2 2 +Ribosomal L18e/L15P superfamily [IPR036227] 0.3962348235507981 0.0656677303967384 0.9476423643510848 1.0 1.0 3 Q9P015 1 +High mobility group box domain superfamily [IPR036910] 0.2827083840818186 0.0573807375275405 0.9542419069435992 1.0 1.0 11 P17480,Q969G3 2 +NET domain superfamily [IPR038336] 0.5225048923678876 0.053480282896314 0.9573492401335064 1.0 1.0 2 O60885 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.3800978792822208 0.0510594915113072 0.959278114954488 1.0 1.0 3 P18206,P35221 2 +ISWI, HAND domain superfamily [IPR036306] 0.5097847358121158 0.047004579739875 0.96250957746054 1.0 1.0 2 P28370 1 +eRF1, domain 2 superfamily [IPR042226] 0.493803000652296 0.0402259335167407 0.9679130024024384 1.0 1.0 2 Q9BRX2 1 +PEBP-like superfamily [IPR036610] 0.4918460534898755 0.0394916341361339 0.9684984233076124 1.0 1.0 2 P30086 1 +MAN1, winged-helix domain [IPR041885] 0.4856490541421939 0.0372948713434717 0.9702498947248032 1.0 1.0 2 Q9Y2U8 1 +F-box-like domain superfamily [IPR036047] 0.4853228962817887 0.0371845264092539 0.970337876216824 1.0 1.0 2 Q13309 1 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.4572733202870089 0.0294616084731848 0.9764964376406476 1.0 1.0 2 Q9NVN8 1 +Arrestin-like, C-terminal [IPR014752] 0.4478147423352667 0.0275470058617998 0.9780234488003148 1.0 1.0 2 Q4G0F5 1 +Arp2/3 complex subunit 2/4 [IPR034666] 0.4432485322896169 0.0267282959643539 0.9786764442748142 1.0 1.0 2 O15144 1 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.2914490861618853 0.0246306906157494 0.9803495391497292 1.0 1.0 4 P62750,P62847,P61313 3 +R3H domain superfamily [IPR036867] 0.3370309951060368 0.0241409031829096 0.9807402167977224 1.0 1.0 3 O15226,O95453 2 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.3979125896934066 0.0214935112574544 0.9828519795351676 1.0 1.0 2 Q5JTZ9 1 +MIT domain superfamily [IPR036181] 0.3796477495107536 0.0204458797784283 0.9836876847177456 1.0 1.0 2 O75351 1 +Actin-crosslinking [IPR008999] 0.3633398564905333 0.0198294366704912 0.9841794354296158 1.0 1.0 2 Q14331 1 +FF domain superfamily [IPR036517] 0.3499673842139491 0.0194866335507903 0.9844528999011976 1.0 1.0 2 O75400 1 +2Fe-2S ferredoxin-like superfamily [IPR036010] 0.3470319634703133 0.0194268083157651 0.9845006244983016 1.0 1.0 2 P21912 1 +Nop domain superfamily [IPR036070] 0.3171288743882533 0.0165686179045308 0.986780760405191 1.0 1.0 3 Q8WWY3,Q9Y2X3 2 +Nop, C-terminal domain [IPR042239] 0.3171288743882533 0.0165686179045308 0.986780760405191 1.0 1.0 3 Q8WWY3,Q9Y2X3 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8eeb84234e5e60c672b9420f17e22eb88e331713 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily [IPR036971]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "APC, N-terminal coiled-coil domain superfamily [IPR036149]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenomatous polyposis coli protein [IPR026831]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-dystroglycan domain 2 [IPR027468]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAS domain superfamily [IPR035965]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinolinate phosphoribosyl transferase, N-terminal domain superfamily [IPR037128]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Rad4, beta-hairpin domain 3 superfamily [IPR042488]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/glucose symporter superfamily [IPR038377]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor IIA, beta-barrel [IPR009088]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transglutaminase-like superfamily [IPR036985]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATR", "ATRX", "ATXN10", "AURKB", "BABAM1", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCL2L13", "BCR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BROX", "BSG", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD2", "CAB39", "CABIN1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM120A", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOPC", "GORASP2", "GOT1", "GOT2", "GPD1L", "GPD2", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HBS1L", "HCFC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INTS1", "INTS12", "INTS14", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISOC1", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAM3", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "METAP1", "METTL1", "METTL13", "METTL17", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCBP3", "NCDN", "NCL", "NCOA5", "NDC80", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKB", "PIAS2", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIL1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMS", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX17", "STX3", "STX4", "STX5", "STX7", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMA16", "TMED5", "TMED7", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSPO", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS13D", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF277", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1"], "leading_proteins": ["AARS2", "ABCB1", "ABCC4", "ABHD10", "ACBD3", "ACOX1", "ACSL6", "ADK", "AGAP3", "AHCYL1", "AIFM1", "ALDH1A2", "ALYREF", "ANAPC5", "ANKLE2", "ANXA11", "ANXA4", "ANXA6", "ANXA7", "APMAP", "ARMT1", "ARPC2", "ASH2L", "ATP13A1", "ATP7B", "BCR", "BRD4", "CALU", "CASK", "CENPB", "CERS2", "CIRBP", "CLUH", "COA7", "COX2", "CPSF7", "CRTAP", "CTNNA1", "CYB5B", "CYB5D2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB12", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DUSP9", "DYNLL1", "ECE1", "EIF3L", "EIF4B", "ELAVL1", "EPHX1", "EPHX2", "ERLIN1", "ESF1", "ETFDH", "EWSR1", "EXOSC2", "EXOSC5", "EXOSC7", "FKBP10", "FKBP14", "FKBP7", "FLOT2", "FOXK1", "FOXRED1", "FRG1", "FUBP1", "FUBP3", "FUS", "GAK", "GALNT1", "GAPVD1", "GET4", "GNA13", "GNAI2", "GNG12", "GNL3L", "HADH", "HDGFL2", "HLA-A", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HNRNPUL1", "IGF2BP2", "IGF2R", "KDM1B", "KDSR", "KHDRBS3", "KHSRP", "KIFBP", "KLC4", "LARP4", "LARP4B", "LEMD3", "LGALS3BP", "LMNA", "LMNB2", "MAU2", "MFSD5", "MGEA5", "MICU1", "MICU2", "MID1", "MPP2", "MPP6", "MRPL15", "MTX1", "MTX3", "NAA40", "NAP1L1", "NAP1L4", "NCBP3", "NENF", "NGEF", "NKRF", "NNT", "NONO", "NOP58", "NPEPPS", "NT5C3B", "NT5DC1", "NUCB1", "NUCB2", "NUP35", "P3H1", "P3H4", "P4HA1", "PABPN1", "PARN", "PCYOX1", "PEBP1", "PECR", "PELO", "PFDN6", "PGRMC2", "PHB2", "PLA2G15", "PLXNB2", "PMPCA", "POMGNT2", "PPT2", "PRCP", "PREPL", "PROCR", "PRPF31", "PRPF40A", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "PSME1", "PSME2", "PSPC1", "PTBP2", "PTGR2", "PTPRF", "PTRH2", "RACGAP1", "RALY", "RANBP9", "RAVER1", "RBM10", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM3", "RBM4", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCN1", "RCN2", "RETSAT", "RMDN1", "RMDN3", "RPL15", "RPL23A", "RPS24", "SCAF4", "SCCPDH", "SCPEP1", "SDHB", "SFPQ", "SGTA", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A20", "SLC25A26", "SLC27A2", "SLC29A1", "SLC4A1AP", "SLTM", "SMARCA1", "SMARCD2", "SMARCE1", "SNRNP70", "SNRPA", "SPNS1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF7", "SRSF9", "STOML2", "STX12", "STX17", "SYNCRIP", "TAF15", "TBC1D9B", "TBCB", "TBCE", "TIA1", "TRA2A", "TRA2B", "TRIM21", "TRIM4", "TTC19", "UBTF", "UNC119B", "UQCRC2", "UTP6", "UXT", "VAT1", "VCL", "VDAC1", "VPS26B", "VPS4B", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2", "ZC3H18", "ZFR"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b219a486844b352cab7762b2c24ccf344d881df8 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:83ba5172ba19c68be8d43fc895cc00a2b45a7a47ef8744cd49e3d59043088842 +size 67950 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..789049da5a5a9c6c84271dac7ba39ba48fd850a1 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..812ec494b5235d59aea7b9611c9ae52399b676ee --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..802a69112361afbad4c4b7413c9ffa80278542ee --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7108934661618375 1.5335016838198678 0.1251522920926053 0.4142263480619659 0.1668697227901404 5 Q9HD20,P35670 2 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f613eb66155da59cb753c22b2e05d919de515acf --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP7B", "EIF5A", "FASN", "LRP1", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP7B"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d41dbfeaca6c45daeac5e1706afc00dc28bb67aa --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5a455b4f000c373e731b0391c75cafc922f5d5f2e90fba30e00250e2d645db3f +size 74188 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4b513ff576a4fe32218693d19a8988850de7dae7 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 3 18 2.5891969090779567 0.0096200067660296 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0039499816510121 0.0142466262053111 0.005693097574516 0.0128293519549119 0.0353817250131281 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0b0b9c580fa9a9f45cd95a070871c937734634af --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 76, + "title": "Average number of proteins per term", + "value": 5.302631578947368 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..39196ca075ea2049a80ecee240fa2a2898666acf --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3b1f8d4b9a4c351a1f9a24a2ac9daa08f47a3727 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.6763767725442996 2.5891969090779567 0.0096200067660296 0.5203314450377262 0.217695639034267 18 Q9UBX3,O43772,Q70HW3 3 +Annexin repeat [IPR018502] 0.7461552737983435 1.6912421852282606 0.0907905570565641 0.9992781295599102 0.3094599874667523 6 P50995,P09525,P20073,P08133 4 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8e99ee4e142566084dc642f0d52de6647f79c52b --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Adenomatous polyposis coli (APC) repeat [IPR041257]", "Adenomatous polyposis coli protein repeat [IPR009223]", "Adenomatous polyposis coli protein, 15 residue repeat [IPR009240]", "Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "SAMP [IPR009224]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "APC", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "ATR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CABIN1", "CAST", "CDC16", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EHMT1", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HTT", "HUWE1", "IGF2R", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NFKB2", "NHLRC2", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PGGT1B", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SGTA", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", 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0.0007737919471253 28.216019417475728 85.92718446601941 -0.2228919145260391 0.5576962459005645 10.340533670084309 5.761399745220316 1.278825309378284 0.3629423837638368 1.0 1.0 0.7032010689619301 4.694071871428781e-05 1.2423906413681017e-07 +Negative regulation of mrna splicing via spliceosome 6 15 2.9837097374773296 0.0028477678464879 6.087378640776699 15.199029126213592 0.1078323316448317 0.4870213286066137 2.88823121239329 1.0677073837920623 1.2108018519405566 0.3438522963849697 1.0 1.0 1.0 3.86876847347757e-06 1.8433829013364647e-05 +Intracellular protein transmembrane transport 6 21 2.9292360091230627 0.0033979631302398 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0005400745195852 0.0012844156650938 0.0008840144918394 0.000686888501954 0.0055591316089767 +Negative regulation of mrna processing 6 21 2.923607089094367 0.0034600118556447 7.699029126213592 21.66747572815534 0.1748680804835885 0.5472984180526073 3.879457852865703 1.8456483684321656 1.0884740123370542 0.3440194219213014 1.0 1.0 1.0 4.476197901851534e-05 0.0002958707603858 +Protein transmembrane import into intracellular organelle 5 13 2.770480411658453 0.005597366687321 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0001093713939637 0.0003865639533612 0.0001815434943904 0.0006827439557333 0.0027845492980534 +Mitochondrial transmembrane transport 13 52 2.768906873523536 0.0056244709185779 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 5.224689675500352e-07 1.4097349879370418e-07 1.0872801784506749e-07 1.0800871238854392e-07 5.3235976749312936e-05 +Regulation of blood pressure 3 18 2.7441227155128645 0.0060672852414194 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0128060111619703 0.0026733926607684 0.0022887430854204 0.0509365284789281 0.3103471330794518 +Protein targeting 37 108 2.68924553106768 0.0071613723884842 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 0.0051876508175514 0.0012073658800308 0.0001428671553367 0.0001202624109886 8.47743088056497e-05 +Protein localization to mitochondrion 23 61 2.681799589750732 0.0073227313825632 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 3.266448447030894e-06 1.1865330087601467e-05 7.51137443801525e-08 1.839726843639583e-06 1.970070511196497e-07 +Protein transmembrane transport 8 25 2.6810191932333165 0.0073398306015335 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0010084504668707 0.000115947693888 0.0001474440444245 3.5525803469399624e-05 0.0009139057009217 +Negative regulation of rna splicing 6 17 2.669506055330675 0.007596290339783 6.550970873786408 17.652912621359224 0.080708148531743 0.5352211753198439 3.085327637418694 1.454292695708865 1.0888581549716274 0.3350559056430555 1.0 1.0 1.0 1.734109635655837e-05 0.0001024209024739 +Protein targeting to mitochondrion 15 48 2.603639647101899 0.0092239681912027 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 8.66935748399017e-06 3.613073613243292e-06 1.4734686191421997e-07 1.204336191435418e-06 8.756102334620714e-07 +Negative regulation of mrna metabolic process 14 44 2.5940711845098887 0.0094846847106013 15.78640776699029 45.30339805825243 0.4317654752348391 0.5186468695555119 6.004287279655988 2.910090931551649 1.3207774317424965 0.3775544483756486 0.4577429689202223 1.0 0.152127800544383 1.2680201104865157e-07 1.4164850720982666e-06 +Protein import into mitochondrial matrix 1 8 2.560185327114868 0.0104616357405777 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0068755162594031 0.0022827689145391 0.0088504827764808 0.0495157384890535 0.1630814235328921 +Inner mitochondrial membrane organization 10 22 2.518893019777024 0.01177244189252 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.0387024754365695 0.0007225305704933 0.0052800410185589 0.001820540651884 0.0017617577033715 +Regulation of mrna splicing via spliceosome 27 62 2.441243150658314 0.0146367960834463 20.90776699029126 63.19417475728155 -0.0284228947141631 0.5570393050560812 8.11843388838484 4.171815400572056 1.3006194329456693 0.3699711363352614 1.0 1.0 0.5782406044087871 1.3626218603682728e-06 6.299990431357981e-09 +Carbohydrate derivative transport 7 19 2.439436552041172 0.0147101856048641 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0573071762398905 1.0 0.0720571885403784 0.0048028453089964 0.0014891058006406 +Calcium ion import 7 12 2.415326382155012 0.0157211153817522 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.269454491362586 0.0135379522122687 0.048990890514732 0.0116952906397438 0.0081853110588452 +Negative regulation of mrna catabolic process 12 24 2.3854653140903204 0.0170575308422873 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 0.3175041114054299 1.0 0.0693457394610891 9.063996119237736e-05 0.0002580266226921 +Rna stabilization 12 26 2.3489608898695407 0.0188258841169357 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 0.340343795801659 1.0 0.0803922289273931 0.0001580597168237 0.0005033411943392 +Purine ribonucleoside metabolic process 3 8 2.314282307252193 0.020652241657328 2.063106796116505 7.834951456310679 1.2047777662844132 0.2574288772305114 1.199068432200366 0.6246876870736083 0.9870596763535292 0.2611531847589775 0.0088086754062598 0.0029386578360865 0.0005309775927247 0.0006143549700213 0.0078812527225172 +Ribonucleoside metabolic process 3 8 2.314282307252193 0.020652241657328 2.1189320388349513 8.12621359223301 1.1914157696469383 0.2635896161542528 1.2648845164842024 0.7462477223524518 0.9827848183963048 0.2624193088278075 0.0172077253384071 0.0058373227860703 0.0015052123544451 0.0024022577840735 0.0269295467729808 +Connective tissue development 9 23 2.311651255595636 0.0207969096122908 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.2937926201392393 0.462328834210194 0.3491903780040699 0.1968043466135108 0.0928229237074456 +Mitochondrial calcium ion homeostasis 7 11 2.2986782901024188 0.021523214204689 4.62621359223301 10.509708737864075 0.2790428491871666 0.3774917598770124 2.1634860921400008 1.7383182679254283 1.294226020505384 0.3175561312397286 1.0 0.0963063052639835 0.1837383274168749 0.0014320459890063 0.0028145739091465 +Cytochrome complex assembly 8 13 2.254651036608468 0.0241552412686443 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0331324948886555 1.0 0.0420348553288257 0.0086864012748381 0.0229507437408614 +Response to food 2 5 2.217667458881606 0.0265775145825033 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 0.0051636995807174 0.0017062060788896 0.0066572828402184 0.0033170374819039 0.0225979674873623 +Adipose tissue development 3 10 2.2144953912519605 0.0267947193959423 2.8640776699029127 10.633495145631068 0.6773213725750321 0.4411668918910317 1.6431590678089345 1.8005243080716844 0.8050216653463795 0.2853255311001682 0.2246782895314235 0.134742527043449 0.2518545844225215 0.1627514901813832 0.0553856285019619 +Calcium import into the mitochondrion 5 8 2.211247223816819 0.0270187218256587 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.0966999925589776 0.0014481500629001 0.0056684159955205 0.0001405335592956 0.0019884945269669 +Body fluid secretion 3 14 2.1737109193628688 0.0297268520962916 3.611650485436894 13.691747572815531 0.5614164790218804 0.4834047231691153 2.085469888187935 1.6735027663843434 0.894552067234308 0.3061879015966331 0.0005400745195852 0.0012844156650938 0.0008840144918394 0.0227330174276438 0.0655768501043339 +Modified amino acid transport 2 5 2.1566869256587644 0.0310300663799512 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 0.0121065438957565 0.0919337377678228 0.0155240337321844 0.0116756742779249 0.0701952648708137 +Sulfur compound transport 3 11 2.146864650165164 0.0318040585939156 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0026332302241178 0.1471951297158956 0.0038117145357013 0.0078094686864188 0.0203628052401783 +Mitochondrial calcium ion transmembrane transport 3 11 2.1460019444214207 0.0318728235649459 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.1268321491559422 0.0026008925831016 0.0100519320580488 0.0004788146962384 0.0062633876942655 +Cellular metabolic compound salvage 2 10 2.1391681400059896 0.0324220534651846 2.7111650485436893 10.342233009708735 0.6130022979591714 0.432432246703952 2.283663298329598 1.399328155048808 1.034909334157758 0.3166979119501528 0.0172077253384071 0.0058373227860703 0.0219975904219434 0.0193169154759243 0.1083207684216986 +Response to cold 4 11 2.13766684696863 0.0325437920910229 3.2063106796116503 11.762135922330096 -0.180809603809966 0.5021052609627927 1.8403933150181828 1.3712453771800803 0.958615312577382 0.2831803681488195 0.0279116150285951 0.1389130578490434 0.0031841845740684 0.0062346640440273 0.0157766780310383 +Phosphatidylcholine metabolic process 2 8 2.132465440466075 0.0329686026342954 3.75 12.592233009708735 0.9144963280277142 0.2812959412325629 1.879404212556404 2.4412987678409657 1.1545250012369797 0.2602001877022786 0.2817714620506266 1.0 0.0538434207197609 0.0671599559498881 0.2936288791787133 +Regulation of alternative mrna splicing via spliceosome 15 30 2.107833157808422 0.0350454236399326 10.609223300970871 30.575242718446603 0.1468114472042654 0.5502297177540902 5.108075880658377 2.6128265930148187 1.194088433027589 0.3536418549118582 1.0 1.0 1.0 0.0010882828125207 9.85983881561296e-05 +Peptide catabolic process 2 10 2.095361461068894 0.0361388727060589 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0005092125406637 9.575570058867652e-05 0.0007461625149634 0.0101015401572799 0.0118865434534573 +Sterol homeostasis 4 10 2.0755320551737886 0.0379372511729891 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.2756388514214415 1.0 0.3076603852203092 0.2332121755087385 0.0353817250131281 +Positive regulation of mitochondrial translation 2 7 2.070185120206047 0.0384350121444256 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0068755162594031 0.0697581245313758 0.0088504827764808 0.0495157384890535 0.0334620993119388 +Toll like receptor signaling pathway 3 13 2.0598071356493164 0.0394169821497176 3.6529126213592233 14.475728155339803 0.4591583663944621 0.4629288770135975 2.064121680704246 2.5201890058346033 0.9793418922124256 0.3026110620517385 0.4530976751092571 0.290515894493261 0.1487873266068847 0.092069152986564 0.4545916116320574 +Ceramide transport 1 5 2.052953622479171 0.0400770756591142 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.1043280169744231 1.0 0.1180585699575878 0.0379575415698398 0.1289341732663725 +Trophectodermal cell differentiation 0 6 2.041306801162189 0.0412203414819249 1.8786407766990292 5.771844660194175 0.2193516802673712 0.5360986134379336 1.710853445428719 0.9982428713687248 0.924068455384751 0.3106656708797944 0.1342086162653788 0.0786913117950012 0.1515272625734178 0.3400030327298383 0.5711774547855736 +Alternative mrna splicing via spliceosome 19 41 2.0287564161140965 0.0424831065132771 14.009708737864075 40.728155339805824 0.0708159133159534 0.5694011596603432 6.451830696216548 3.032011011191426 1.225863726972057 0.3649890000258197 1.0 1.0 1.0 0.0008410935227018 9.589894388561307e-06 +Terpenoid metabolic process 8 19 2.026821618556956 0.0426806587347059 4.992718446601942 17.42233009708738 0.6301104025923489 0.3704291423404849 2.365292196147205 2.02323551503238 1.1104102314092092 0.2862846297230793 0.2938831434499784 0.1795501084992132 0.0588586045542952 0.0756846958642696 0.0006746347610051 +Purine containing compound salvage 2 7 2.024089614141962 0.0429609320412844 1.8737864077669903 7.233009708737864 0.7743343410521683 0.3736672462346809 1.748395167894324 0.8238423298008908 1.0837559690437977 0.3116170205148165 0.0043932683594101 0.0014481500629001 0.0056684159955205 0.0025975272437437 0.018020673376298 +Vascular transport 5 14 1.990695362077924 0.0465143889202535 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 0.0663917661816688 1.0 0.0832345551471358 0.03203241935523 0.0330537609250841 +Mitochondrial membrane organization 20 48 1.9831191609122156 0.0473541208015724 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.0087015384546561 0.0011305823171669 0.0003120858048586 0.002183892978537 0.0007129331320898 +Bone morphogenesis 4 7 1.9758114184604167 0.0481761397112527 2.3737864077669903 7.519417475728155 0.7918915806069479 0.3290665752918499 1.3241931901591228 1.4011478132752644 1.0549507058478411 0.2731796281548322 1.0 1.0 1.0 0.2961580697833918 0.0655768501043339 +Negative regulation of g protein coupled receptor signaling pathway 0 6 1.9709065365180107 0.0487345673375978 1.949029126213592 6.490291262135922 0.2084532251246883 0.5412265961193776 1.4663951007094485 1.1004866146177228 0.9002696563192922 0.3020955876409478 0.1631035739222515 0.0963063052639835 0.1837383274168749 0.4015375820029667 0.6487121027608701 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..271ebf12993631e786a92a5cfbf4c678339052e8 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 6394, + "title": "Average number of proteins per term", + "value": 18.624178917735378 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8e524d451258c6d5d75c1ca8cc29ddfe58384119 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cb0d1b2f1ae0128f00f0b9ad585847804cc8bfcf --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1426 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial transport 0.6025171782361153 4.512670783148354 6.401634977226678e-06 0.0401057770911784 0.0409320540443937 85 Q99595,O75431,O60830,Q5JRX3,Q9UII2,Q8N4Q1,P55786,O43772,P62072,Q9NS69,Q8N4H5,O75964,O95831,P00846,Q96EK5,P51572,P52789,Q9UBX3,Q10713,P30536,P10809,P23786,Q9Y584,P45880 24 +Regulation of rna splicing 0.5442890163057594 3.8505370143942073 0.0001178591154951 0.5293476635801484 0.3767955922378743 87 Q9Y5S9,P84103,Q08170,Q96PU8,P31942,Q8WVV9,Q13242,P52597,P55795,P61978,P08621,Q9NW64,Q07955,P52756,P22626,Q14011,Q5BKZ1,O75525,P31943,Q13595,Q9BWF3,P31483,O75494,Q92841,P49756,P35637,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,Q9UKA9,P98179,Q96E39,Q96T37,P38159,P09651 37 +Regulation of mrna processing 0.5001827136849645 3.362003314738176 0.0007737919471253 0.9929133384335525 0.9470260567654644 85 Q9Y5S9,Q8N684,P84103,Q08170,Q96PU8,Q13242,Q07666,P61978,P08621,P52756,P22626,P09012,Q14011,O43865,O75525,Q13595,Q9BWF3,P31483,O75494,Q92841,P49756,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,P98179,Q96E39,Q96T37,P38159,P09651 31 +Negative regulation of mrna splicing via spliceosome 0.8043279777839851 2.9837097374773296 0.0028477678464879 0.999999987954852 0.9470260567654644 15 P22626,O75494,P61978,Q16629,P98175,P38159 6 +Intracellular protein transmembrane transport 0.7372466687858595 2.9292360091230627 0.0033979631302398 0.999999999646654 0.9470260567654644 21 Q99595,P10809,O60830,Q15629,O95831,O75381 6 +Negative regulation of mrna processing 0.736277536744911 2.923607089094367 0.0034600118556447 0.9999999997626956 0.9470260567654644 21 P22626,O75494,P61978,Q16629,P98175,P38159 6 +Protein transmembrane import into intracellular organelle 0.7973804123921042 2.770480411658453 0.005597366687321 0.9999999999999998 0.9470260567654644 13 Q99595,P10809,O60830,O95831,O75381 5 +Mitochondrial transmembrane transport 0.64856594005978 2.768906873523536 0.0056244709185779 0.9999999999999998 0.9470260567654644 52 Q99595,Q8IYU8,O60830,P10809,P23786,Q9BPX6,O75964,O95831,P00846,Q9BQT8,P21796,O43772,Q9H4I9 13 +Regulation of blood pressure 0.702673628587944 2.7441227155128645 0.0060672852414194 1.0 0.9470260567654644 18 P42892,Q9UIQ6,P42785 3 +Protein targeting 0.4662083621725983 2.68924553106768 0.0071613723884842 1.0 0.9470260567654644 108 Q9P275,Q99595,O60830,P57105,Q5JRX3,Q9Y5M8,O14964,Q9UII2,Q14108,Q9P0J0,Q8N4Q1,P55786,P62072,Q3ZCQ8,Q9NS69,Q8N4H5,O43765,O14925,O95831,P51572,Q7L5D6,O75381,P40855,P56589,Q10713,P30536,P10809,O00170,O14737,Q9Y584,P46379,O60725,Q15629,Q9H173,P43307,Q99523,Q96RT1 37 +Protein localization to mitochondrion 0.5905838932447756 2.6817995897507316 0.0073227313825632 1.0 0.9470260567654644 61 Q99595,Q9P275,O60830,Q5JRX3,Q15070,Q9UII2,Q9P0J0,Q8N4Q1,P55786,Q9Y6C9,P62072,Q3ZCQ8,Q9NS69,Q8N4H5,O95831,P51572,P52789,Q10713,P30536,Q9Y276,P10809,O14737,Q9Y584 23 +Protein transmembrane transport 0.6968705060254782 2.6810191932333165 0.0073398306015335 1.0 0.9470260567654644 25 Q99595,O60830,P10809,Q9NS69,Q15629,Q9Y584,O95831,O75381 8 +Negative regulation of rna splicing 0.7087833910202307 2.669506055330675 0.007596290339783 1.0 0.9470260567654644 17 P22626,O75494,P61978,Q16629,P98175,P38159 6 +Protein targeting to mitochondrion 0.6432542452122192 2.603639647101899 0.0092239681912027 1.0 0.9470260567654644 48 Q99595,O60830,P62072,Q9NS69,Q8N4H5,P10809,Q5JRX3,Q9Y584,O95831,Q9UII2,P51572,Q8N4Q1,P55786,Q10713,P30536 15 +Negative regulation of mrna metabolic process 0.6553765235889234 2.5940711845098887 0.0094846847106013 1.0 0.9470260567654644 44 P22626,O75494,Q13151,P61978,Q14011,P67809,P35637,Q16629,P98175,P07910,O60506,Q92804,P38159,Q13242 14 +Protein import into mitochondrial matrix 0.8660225339711376 2.560185327114868 0.0104616357405777 1.0 0.9470260567654644 8 Q99595 1 +Inner mitochondrial membrane organization 0.66906468298208 2.518893019777024 0.01177244189252 1.0 0.9470260567654644 22 O75431,Q13505,P62072,Q5HYI7,Q9Y584,Q16891,Q9Y4W6,Q9P0J0,Q9NX63,Q9H3K2 10 +Regulation of mrna splicing via spliceosome 0.5576156172499482 2.441243150658314 0.0146367960834463 1.0 0.9470260567654644 62 Q9Y5S9,P84103,Q08170,Q96PU8,Q13242,P61978,P08621,P52756,P22626,Q14011,O75525,Q13595,Q9BWF3,P31483,Q92841,O75494,P49756,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,Q96E39,P98179,Q96T37,P38159,P09651 27 +Carbohydrate derivative transport 0.6528407524926696 2.4394365520411716 0.0147101856048641 1.0 0.9470260567654644 19 P07602,Q99808,P41440,O15439,Q8TB61,Q8TDW0,Q8WTV0 7 +Calcium ion import 0.7415286529246585 2.415326382155012 0.0157211153817522 1.0 0.9470260567654644 12 Q8IYU8,O14936,O75844,Q9BPX6,Q9Y4W6,P21796,Q9H4I9 7 +Negative regulation of mrna catabolic process 0.6488405885066089 2.3854653140903204 0.0170575308422873 1.0 0.9470260567654644 24 Q14103,Q13151,P35637,Q14011,P67809,Q99729,Q15717,Q9Y2W1,P98175,P07910,O60506,Q92804 12 +Rna stabilization 0.6438561145582687 2.3489608898695407 0.0188258841169357 1.0 0.9470260567654644 26 Q14103,Q13151,P35637,Q14011,P67809,Q15717,Q9Y2W1,P98175,P07910,O60506,Q92804,Q08J23 12 +Purine ribonucleoside metabolic process 0.8100677959881043 2.314282307252193 0.020652241657328 1.0 0.9470260567654644 8 Q13126,O60725,P00813 3 +Ribonucleoside metabolic process 0.8100677959881043 2.314282307252193 0.020652241657328 1.0 0.9470260567654644 8 Q13126,O60725,P00813 3 +Connective tissue development 0.6364292483164303 2.311651255595636 0.0207969096122908 1.0 0.9470260567654644 23 O75844,P35610,P11802,Q15043,Q92896,P08133,P43490,Q96HY6,O15173 9 +Mitochondrial calcium ion homeostasis 0.7415511192797786 2.2986782901024188 0.021523214204689 1.0 0.9470260567654644 11 Q8IYU8,Q9BPX6,Q96AQ8,Q9Y4W6,P51572,P08133,Q9H4I9 7 +Cytochrome complex assembly 0.696862865763042 2.254651036608468 0.0241552412686443 1.0 0.9470260567654644 13 Q5U5X0,Q9Y276,Q6DKK2,P53701,O75880,Q69YU5,Q15070,Q9Y2R0 8 +Response to food 0.8757538453774849 2.217667458881606 0.0265775145825033 1.0 0.9470260567654644 5 P80303,Q9UMX5 2 +Adipose tissue development 0.7462980203499077 2.2144953912519605 0.0267947193959423 1.0 0.9470260567654644 10 O15173,P11802,P43490 3 +Calcium import into the mitochondrion 0.787108535574486 2.211247223816819 0.0270187218256587 1.0 0.9470260567654644 8 Q8IYU8,Q9BPX6,Q9Y4W6,P21796,Q9H4I9 5 +Guanine nucleotide transmembrane transport 0.949149181210543 2.1896638787102636 0.028548622567309 1.0 0.9470260567654644 4 O15439,P41440 2 +Guanine nucleotide transport 0.949149181210543 2.1896638787102636 0.028548622567309 1.0 0.9470260567654644 4 O15439,P41440 2 +Body fluid secretion 0.6682211066332095 2.1737109193628688 0.0297268520962916 1.0 0.9470260567654644 14 P00403,Q13505,P00813 3 +Modified amino acid transport 0.8606070030036652 2.1566869256587644 0.0310300663799512 1.0 0.9470260567654644 5 O15439,O43772 2 +Sulfur compound transport 0.7110693520276808 2.1468646501651634 0.0318040585939156 1.0 0.9470260567654644 11 O15439,Q9UBX3,Q70HW3 3 +Mitochondrial calcium ion transmembrane transport 0.7108976090819336 2.1460019444214207 0.0318728235649459 1.0 0.9470260567654644 11 Q8IYU8,P21796,Q9H4I9 3 +Cellular metabolic compound salvage 0.7307208058535272 2.1391681400059896 0.0324220534651846 1.0 0.9470260567654644 10 Q13126,P00813 2 +Response to cold 0.7092391408886352 2.13766684696863 0.0325437920910229 1.0 0.9470260567654644 11 P00403,P10809,Q14011,P17252 4 +Phosphatidylcholine metabolic process 0.7697384989123033 2.132465440466075 0.0329686026342954 1.0 0.9470260567654644 8 Q8NCC3,Q8WTV0 2 +Regulation of alternative mrna splicing via spliceosome 0.6070695804873687 2.107833157808422 0.0350454236399326 1.0 0.9689825335337124 30 Q9Y5S9,Q9BWF3,P31483,Q92841,P49756,Q07666,Q8IY67,Q9Y2W1,P98175,P62995,P52756,P09651,Q96T37,P38159,O75525 15 +Peptide catabolic process 0.7217218719459471 2.095361461068894 0.0361388727060589 1.0 0.9700023554440806 10 P42892,P55786 2 +Sterol homeostasis 0.7176626588476144 2.0755320551737886 0.0379372511729891 1.0 0.9700023554440806 10 P35610,P34913,O15118,Q8WTV0 4 +Positive regulation of mitochondrial translation 0.7967310740821529 2.070185120206047 0.0384350121444256 1.0 0.9700023554440806 7 Q9Y2R0,Q567V2 2 +Toll like receptor signaling pathway 0.6604043690334888 2.0598071356493164 0.0394169821497176 1.0 0.9841591800933932 13 Q9NPR9,P10809,P41440 3 +Ceramide transport 0.8350687214842228 2.052953622479171 0.0400770756591142 1.0 0.9860588753952292 5 P08183 1 +Alternative mrna splicing via spliceosome 0.5846962945053059 2.0287564161140965 0.0424831065132771 1.0 0.9967268651922684 41 Q9Y5S9,P23246,Q13242,Q07955,P52756,Q14004,O75525,Q9BWF3,P31483,Q92841,P49756,Q96I25,Q8IY67,Q9Y2W1,P98175,P62995,Q96T37,P38159,P09651 19 +Terpenoid metabolic process 0.5864141121681016 2.026821618556956 0.0426806587347059 1.0 0.9967268651922684 19 Q9BY49,P37268,Q9HB40,Q9HBH5,O94788,Q6NUM9,Q9Y394,P51648 8 +Purine containing compound salvage 0.7861097524056747 2.024089614141962 0.0429609320412844 1.0 0.9967268651922684 7 Q13126,P00813 2 +Vascular transport 0.6351875434166442 1.990695362077924 0.0465143889202535 1.0 0.9967268651922684 14 P41440,O15439,P30825,P08183,P53985 5 +Mitochondrial membrane organization 0.5623586545514879 1.9831191609122152 0.0473541208015724 1.0 0.9967268651922684 48 O75431,Q5HYI7,Q15070,Q9UII2,Q9P0J0,Q9NX63,Q9H3K2,Q13505,P62072,Q3ZCQ8,Q9NS69,P52789,Q9Y276,O14737,Q9Y584,Q16891,P45880,Q9Y4W6,Q8IXI1,Q8IWA4 20 +Bone morphogenesis 0.7750416609429682 1.9758114184604172 0.0481761397112527 1.0 0.9967268651922684 7 Q92896,Q7Z3C6,P08133,O75844 4 +Negative regulation of rna catabolic process 0.5845022133341322 1.9581658170460905 0.0502105587587948 1.0 0.9967268651922684 32 Q14103,Q13151,P35637,Q14011,P67809,Q15717,Q99729,Q9Y2W1,P98175,P07910,O60506,Q92804,Q08J23 13 +Positive regulation of response to endoplasmic reticulum stress 0.8094561908065145 1.9570149428275936 0.0503457115436811 1.0 0.9967268651922684 6 P46379,P51572 2 +Regulation of b cell apoptotic process 0.8101379310463108 1.9505989395894376 0.0511047734614842 1.0 0.9967268651922684 5 P00813 1 +Gland development 0.4883101282230289 1.944399029546569 0.0518473508071779 1.0 0.9967268651922684 65 Q13505,P00813,P07602,P00403,P52789,O94788,Q96JB5,Q9NQC3,P30536 9 +Detection of biotic stimulus 0.8082126182981759 1.9426506958757743 0.0520583771514953 1.0 0.9967268651922684 5 Q8WTV0 1 +Circulatory system process 0.4204629533796712 1.942023970726664 0.0521341984791399 1.0 0.9967268651922684 76 P00813,Q99808,O75844,P41440,O15439,Q9UIQ6,P42785,P30825,Q9HB40,P08183,P17252,P42892,P53985 13 +Nucleobase containing small molecule biosynthetic process 0.7673272142392152 1.942015964497959 0.0521351676713737 1.0 0.9967268651922684 7 Q13126,P00813 2 +Glycosyl compound biosynthetic process 0.7673272142392152 1.942015964497959 0.0521351676713737 1.0 0.9967268651922684 7 Q13126,P00813 2 +Regulation of mitochondrial gene expression 0.689659458109183 1.9375763494554523 0.0526749302105342 1.0 0.9967268651922684 10 Q9Y2R0,Q567V2,Q6P087 3 +Fatty acid transmembrane transport 0.8043635752346521 1.935880764633156 0.0528823061364152 1.0 0.9967268651922684 6 P33121,O43772,P23786 3 +Purine containing compound transmembrane transport 0.6888503915617648 1.9335608163411655 0.0531671488570246 1.0 0.9967268651922684 10 O15439,Q8TDW0,Q99808,P41440 4 +Organic cation transport 0.8036310714316985 1.9328371964396325 0.0532562565582783 1.0 0.9967268651922684 6 Q70HW3 1 +Deoxyribonucleoside triphosphate metabolic process 0.725725358825761 1.9296732647082504 0.0536473346077583 1.0 0.9967268651922684 8 Q9H773,P00813 2 +Positive regulation of mitochondrial calcium ion concentration 0.8046135217408856 1.9277760351312856 0.0538829897916439 1.0 0.9967268651922684 5 Q8IYU8,P51572,Q9BPX6 3 +Regulation of toll like receptor signaling pathway 0.7065612803141283 1.926602787328411 0.0540291510280985 1.0 0.9967268651922684 9 Q9NPR9,P41440 2 +Nucleoside triphosphate catabolic process 0.8043140207260187 1.9265372623045856 0.0540373237722211 1.0 0.9967268651922684 5 P00813 1 +Deoxyribonucleoside triphosphate catabolic process 0.8043140207260187 1.9265372623045856 0.0540373237722211 1.0 0.9967268651922684 5 P00813 1 +Purine nucleoside biosynthetic process 0.7999682008574992 1.917603994028635 0.0551612433207258 1.0 0.9967268651922684 6 Q13126,P00813 2 +Purine ribonucleotide salvage 0.8015987614497532 1.915299853933896 0.0554542742239219 1.0 0.9967268651922684 5 P00813 1 +Purine nucleotide salvage 0.8015987614497532 1.915299853933896 0.0554542742239219 1.0 0.9967268651922684 5 P00813 1 +Amp salvage 0.8015987614497532 1.915299853933896 0.0554542742239219 1.0 0.9967268651922684 5 P00813 1 +Regulation of mrna metabolic process 0.4335664590591214 1.9134053045547468 0.0556961858412137 1.0 0.9967268651922684 142 Q9Y5S9,Q8N684,P84103,Q13868,Q08170,Q15717,Q969T7,Q96PU8,Q15024,Q13242,Q14103,Q07666,P61978,Q13151,P08621,P67809,Q99729,Q9NWH9,P17252,O60506,Q92804,P52756,P22626,Q9P2K5,P09012,Q14011,Q92945,Q92615,O43865,Q9HBH5,Q9HCE1,O75525,Q13595,Q9BWF3,P31483,O75494,Q92879,Q92841,P49756,P35637,Q13464,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,P07910,P98179,Q96E39,Q96T37,P38159,P09651,P08670 53 +Positive regulation of mrna splicing via spliceosome 0.5801325536463617 1.9055472320446936 0.0567089739125961 1.0 0.9967268651922684 17 P08621,Q14011,Q9Y2W1,P62995,P98179,Q96E39,P38159 7 +Sphingolipid biosynthetic process 0.5764106698830085 1.882517217281335 0.0597658244334182 1.0 0.9967268651922684 17 Q06136,Q99805,O15121 3 +B cell proliferation 0.6768813992380747 1.873965510697106 0.0609351789515915 1.0 0.9967268651922684 10 P00813 1 +Peptidyl lysine hydroxylation 0.7869232201448197 1.863166060223061 0.0624389063505252 1.0 0.9967268651922684 6 Q96AY3 1 +Positive regulation of necrotic cell death 0.7840926237930573 1.851315789070739 0.0641241359276696 1.0 0.9967268651922684 6 P00403,P30536 2 +Maintenance of protein location in mitochondrion 0.9722118162953448 1.848293162580042 0.0645599443293973 1.0 0.9967268651922684 3 P52789 1 +Protein maturation 0.4777280506589589 1.8400337446819908 0.0657632832930354 1.0 0.9967268651922684 65 P10809,Q8TAD4,Q15392,Q8TCT9,O75844,Q5JRX3,O75976,Q86UY6,Q96F07,Q92896,P17252,P42892,Q8N4Q1,Q9BU89,Q9NRN7,Q10713 16 +Cholesterol efflux 0.7051945379114428 1.833556417273503 0.0667198666946922 1.0 0.9967268651922684 8 P35610,O15118,Q8WTV0,Q86Y82 4 +Embryonic digestive tract development 0.9673087208817586 1.830329277285121 0.0672007160081169 1.0 0.9967268651922684 3 P00813 1 +Protein import 0.3817620542113664 1.827065564837742 0.0676899119815301 1.0 0.9967268651922684 88 Q99595,O60830,P52292,Q15717,Q9NPF5,Q8N4Q1,Q3ZCQ8,Q9NS69,P61970,O14925,Q8NFH5,O95831,Q14978,Q9NW64,P40855,O75381,P56589,P10809,O14737,P12270,P02545,Q92973,Q8N1F7 23 +Positive regulation of protein export from nucleus 0.6177732872544278 1.826871397645839 0.0677191076785812 1.0 0.9967268651922684 13 P50402,P12270,P17252,Q9Y3B8,Q14012 5 +Nucleotide salvage 0.7782189733859496 1.8266833113428067 0.0677473989072487 1.0 0.9967268651922684 6 P00813 1 +Nerve development 0.7013267824568823 1.8153442790388512 0.069471018327309 1.0 0.9967268651922684 8 P42892 1 +Response to oxygen levels 0.5033412314170791 1.8148569365658085 0.0695458978657255 1.0 0.9967268651922684 59 P00813,O95831,P00846,P30519,P52789,Q8N511,P55786 7 +B cell apoptotic process 0.7375658923943507 1.8105425741443095 0.0702116883631702 1.0 0.9967268651922684 7 P00813 1 +Phospholipid dephosphorylation 0.8485641874821486 1.8038191747686136 0.0712596588716991 1.0 0.9967268651922684 4 Q10713 1 +Regulation of protein deacetylation 0.6794208202302441 1.7952516374509675 0.0726136166413498 1.0 0.9967268651922684 9 O43823,P49354,Q9ULX6,Q8N163 4 +Cellular component disassembly involved in execution phase of apoptosis 0.7702791562323827 1.7932959772980763 0.0729256102937268 1.0 0.9967268651922684 6 O95831 1 +Isoprenoid metabolic process 0.5544764705909127 1.7910538006905137 0.0732846618780811 1.0 0.9967268651922684 22 Q9BY49,Q15126,P37268,Q9HB40,Q9HBH5,O94788,Q6NUM9,Q9Y394,P51648 9 +Skeletal system morphogenesis 0.5873376160905279 1.7886572316870637 0.0736700346874983 1.0 0.9967268651922684 15 O75844,P16435,Q92896,P08133,Q7Z3C6,O95470 6 +Regulation of receptor recycling 0.7683321386434053 1.7850931027025307 0.0742462165563335 1.0 0.9967268651922684 6 P42892 1 +Respiratory chain complex iii assembly 0.7658225879807302 1.7745113110010098 0.075978612819215 1.0 0.9967268651922684 6 Q5U5X0,Q6DKK2,Q69YU5 3 +Metal ion homeostasis 0.3711239735764066 1.770519931860675 0.0766405670093424 1.0 0.9967268651922684 81 Q15904,Q8IYU8,Q96TC7,Q8TAD4,Q6P4Q7,Q9BPX6,Q9HD20,P30519,P17252,P08133,P51572,Q8N511,P05771,Q9H4I9 14 +Mammary gland development 0.5440307315232058 1.7669623029721566 0.0772345417290183 1.0 0.9967268651922684 18 P00403,Q13505,P52789 3 +Regulation of pattern recognition receptor signaling pathway 0.5440174680507821 1.766876475683304 0.0772489174909847 1.0 0.9967268651922684 18 Q9NPR9,O43657,P41440 3 +Cyclic gmp amp transmembrane import across plasma membrane 0.9463341856782108 1.753230243936391 0.0795624936090155 1.0 0.9967268651922684 3 P41440 1 +Negative regulation of cell population proliferation 0.3779354830678776 1.7510269624196957 0.0799412657721057 1.0 0.9967268651922684 90 Q15392,Q96G23,P57105,Q9NR77,P50402,O14737,Q96DY7,P98175,Q32P28,Q9Y3B8,O94788,Q9UII2,P52756,P30536 14 +Mesenchymal cell development 0.61467724337884 1.7506663465731571 0.0800033995587596 1.0 0.9967268651922684 12 Q14978,P98172,P08133,O94788 4 +Neural crest cell differentiation 0.61467724337884 1.7506663465731571 0.0800033995587596 1.0 0.9967268651922684 12 Q14978,P98172,P08133,O94788 4 +Digestive system development 0.6144666250766349 1.7495251925069948 0.0802002780073471 1.0 0.9967268651922684 12 P00813 1 +Nucleotide transmembrane transport 0.6697304509846949 1.7479448224701088 0.0804735823814253 1.0 0.9967268651922684 9 O15439,Q8TDW0,P41440 3 +Purine nucleotide transport 0.6032134416149161 1.7461240801107496 0.0807893933489263 1.0 0.9967268651922684 13 Q99808,P41440,O15439,Q8TB61,Q8TDW0 5 +Pyridine containing compound metabolic process 0.669277145684539 1.7457267606023097 0.0808584427107972 1.0 0.9967268651922684 9 Q13126 1 +Negative regulation of neuron projection development 0.5418999384885579 1.740534176082178 0.0817652644171469 1.0 0.9967268651922684 19 Q9NQX7,Q9NR77,Q9UL15,Q9NQC3,P08670 5 +Regulation of systemic arterial blood pressure 0.7574747297783571 1.739240158598774 0.0819925283626117 1.0 0.9967268651922684 6 P42785 1 +Positive regulation of mrna processing 0.5448550593753294 1.737416050833382 0.0823137601297554 1.0 0.9967268651922684 21 P08621,Q14011,Q9Y2W1,P62995,Q96E39,P98179,P38159 7 +Nucleotide transport 0.5896612919714196 1.7329176055909388 0.083110314585902 1.0 0.9967268651922684 14 Q99808,P41440,O15439,Q8TB61,Q8TDW0 5 +Protein insertion into mitochondrial inner membrane 0.7201236049777014 1.7327100877377355 0.0831472106216457 1.0 0.9967268651922684 7 P62072,Q9Y584 2 +Regulation of glial cell proliferation 0.7578696429676124 1.732703753348564 0.0831483370652299 1.0 0.9967268651922684 5 P30536 1 +Mrna splice site selection 0.5371515647574469 1.7223654742348986 0.0850033338980083 1.0 0.9967268651922684 18 O75475,Q15428,O75494,Q92879,Q9UKA9,Q07955,Q12874,Q13242 8 +Lactation 0.627830744344079 1.7194171101396456 0.0855384489047008 1.0 0.9967268651922684 11 P00403,Q13505 2 +Negative regulation of b cell apoptotic process 0.8261818029310636 1.7161333883225902 0.0861376314961401 1.0 0.9967268651922684 4 P00813 1 +Blastocyst formation 0.5860998927943281 1.712498811863129 0.0868047833819671 1.0 0.9967268651922684 14 P00813 1 +Gmp salvage 0.8248340056065512 1.7108344507748836 0.0871116779124658 1.0 0.9967268651922684 4 P00813 1 +Collagen metabolic process 0.6617682282152197 1.7089198981027354 0.0874657881421969 1.0 0.9967268651922684 9 Q92791,Q32P28 2 +Inorganic anion transport 0.5477691302825065 1.70849272474174 0.0875449551751115 1.0 0.9967268651922684 28 Q9Y666,O15439,Q9UBX3,Q9Y6M7,Q8TDW0,P08183,Q9UHG3,P45880,P21796,Q6N075,P30536 11 +Organic acid transmembrane transport 0.5484743334263592 1.707526534031695 0.0877242302777032 1.0 0.9967268651922684 31 P28288,P23786,P08195,P41440,P30825,Q8TDW0,P33121,P08183,Q9BQT8,P53985,Q9UBX3,O43772 12 +Glycerophospholipid catabolic process 0.7497942732660028 1.7066937509994031 0.0878789893176219 1.0 0.9967268651922684 6 Q8WTV0 1 +Alcohol catabolic process 0.6430533885067252 1.703658947607722 0.0884448218240423 1.0 0.9967268651922684 10 Q8WTV0,P30837 2 +Myotube differentiation 0.5841126414106007 1.7010902062826614 0.08892604967965 1.0 0.9967268651922684 14 P17655,Q99523,Q8IV08,P41440 4 +Regulation of release of cytochrome c from mitochondria 0.6231008163867194 1.6945974024811057 0.0901518201705173 1.0 0.9967268651922684 11 Q9GZY8,Q9Y255,O14737,P02545,Q9H3K2,P04637 6 +Collagen biosynthetic process 0.8201144886688159 1.6922633158710274 0.0905957789862594 1.0 0.9967268651922684 4 Q92791 1 +Negative regulation of leukocyte apoptotic process 0.7473685919845461 1.6884265732954018 0.091329373005776 1.0 0.9967268651922684 5 P00813 1 +Negative regulation of lymphocyte apoptotic process 0.7473685919845461 1.6884265732954018 0.091329373005776 1.0 0.9967268651922684 5 P00813 1 +Negative regulation of inflammatory response 0.5924179781532686 1.6858885012519291 0.0918172771198417 1.0 0.9967268651922684 13 P00813 1 +Regulation of low density lipoprotein particle clearance 0.7463601291178371 1.6841662898741714 0.0921495360720858 1.0 0.9967268651922684 5 P61978 1 +Amyloid precursor protein biosynthetic process 0.7453476983349604 1.6798878355150375 0.0929791410149394 1.0 0.9967268651922684 5 P35610,Q9NQX7,Q9NY61,Q92542 4 +Positive regulation of rna splicing 0.5400500128832216 1.6786137337097349 0.0932273482232137 1.0 0.9967268651922684 24 P19338,P08621,Q14011,Q13243,Q9Y2W1,P62995,Q9NW64,Q96E39,P98179,P52948,P38159,Q8WVV9,Q13595,Q96QD8 14 +Neutral lipid biosynthetic process 0.7448673389334372 1.677857382194442 0.0933749440491349 1.0 0.9967268651922684 5 Q8NCC3,Q8WTV0 2 +Deoxyribonucleoside monophosphate metabolic process 0.7074559811432125 1.675841240362524 0.0937692937683021 1.0 0.9976461579487164 7 P00813 1 +Cellular response to osmotic stress 0.5999196803855641 1.6704402051653957 0.0948323006080738 1.0 1.0 12 Q8TDW0,P30536 2 +Neutral amino acid transport 0.7409284131724936 1.66901420298477 0.0951145650760061 1.0 1.0 6 P08195,Q15758,Q9H9B4,Q96NB2 4 +B cell activation involved in immune response 0.5544214809859473 1.6656982722391005 0.0957735262936556 1.0 1.0 16 P10809,P00813 2 +Deoxyribose phosphate catabolic process 0.7050922546236206 1.6651990494899016 0.0958730505535137 1.0 1.0 7 P00813 1 +Appendage morphogenesis 0.6515800820277123 1.65878804596673 0.0971585100039678 1.0 1.0 9 P42892,O94788 2 +Appendage development 0.6153906901942978 1.6540289091030749 0.0981216390146531 1.0 1.0 11 P42892,O94788 2 +Forelimb morphogenesis 0.918700684922704 1.6510809523548378 0.098722046133322 1.0 1.0 3 O94788 1 +Export across plasma membrane 0.6140446974518898 1.646932936413224 0.0995718311034241 1.0 1.0 11 P08183 1 +Execution phase of apoptosis 0.6309288822855834 1.641982487054808 0.1005936335340589 1.0 1.0 10 O95831 1 +Negative regulation of blood pressure 0.8070815389573195 1.6408533015509508 0.1008278707263552 1.0 1.0 4 P42785 1 +Regulation of lipoprotein particle clearance 0.7327206224639667 1.6340300623777335 0.1022525384197827 1.0 1.0 6 P61978 1 +Response to testosterone 0.6279414862661648 1.6267375709928429 0.1037928456059877 1.0 1.0 10 Q13126 1 +Protein insertion into membrane 0.5365738656909504 1.6257622139086878 0.1040002494853398 1.0 1.0 30 P62072,Q9Y276,Q9NS69,Q15629,O43765,O14737,Q9Y584,Q15070,Q9P0J0,Q7L5D6,P46379 11 +Regulation of maintenance of sister chromatid cohesion 0.7318017938045736 1.622511759189085 0.1046938173353837 1.0 1.0 5 P41227,P46100 2 +Vascular process in circulatory system 0.5362522679476791 1.6220568495978205 0.1047911762380742 1.0 1.0 31 Q99808,P41440,O15439,P30825,Q9HB40,P08183,P42892,P53985 8 +Regulation of response to osmotic stress 0.7312739189422472 1.6202710125236204 0.1051740729041657 1.0 1.0 5 P08183 1 +Protein hydroxylation 0.5700323975350243 1.6199603145718329 0.1052408020946999 1.0 1.0 14 Q92791,Q32P28,Q96AY3,O75718,Q13162,Q9H267,P13674 7 +Regulation of lymphocyte apoptotic process 0.659873564519679 1.6181713404443163 0.1056256774033097 1.0 1.0 8 P00813,Q96GD4 2 +Regulation of tube size 0.6422752426643744 1.6128163582419837 0.106784411093566 1.0 1.0 9 P42892 1 +Negative regulation of cellular catabolic process 0.367451411016716 1.6089356119077294 0.1076304215309331 1.0 1.0 90 Q9P275,P10619,Q15717,P85037,Q9UL15,Q08J23,Q14103,O43765,Q13151,P08621,P67809,Q99729,Q96KB5,O60506,Q92804,P30536,P49069,Q14011,Q96HY6,P46379,Q08379,P35637,Q9Y2W1,P98175,P07910,O15118,Q92530,Q96JB5 28 +Long chain fatty acid transport 0.5883087510541766 1.6069539928539354 0.1080644608628382 1.0 1.0 12 P33121,O14975,O43772,P23786 4 +Protein ufmylation 0.7983219297259344 1.6062014584402884 0.1082296530254904 1.0 1.0 4 Q96HY6 1 +Isocitrate metabolic process 0.7266542088356807 1.6006461526211455 0.1094553139048808 1.0 1.0 5 P48735 1 +Calcium mediated signaling 0.5204010724865151 1.5997551971770134 0.1096529015025742 1.0 1.0 19 P00813,P17252,O75844 3 +Positive regulation of protein deacetylation 0.724444063001649 1.59865814359819 0.1098965827573617 1.0 1.0 6 O43823,P49354,Q9ULX6 3 +Receptor recycling 0.6900534939921689 1.5972735176308863 0.1102047512526418 1.0 1.0 7 P42892 1 +Regulation of glycoprotein metabolic process 0.5864902233180993 1.596983002772827 0.1102694960944705 1.0 1.0 12 Q9NQX7,Q08379,P35610,Q92542,Q96IZ0,Q9NY61,Q99805,O14734 8 +Regulation of cyclin dependent protein kinase activity 0.5754111496298135 1.5904060109450548 0.1117433162924019 1.0 1.0 13 Q9Y3B8 1 +C4 dicarboxylate transport 0.6540382759115198 1.5901407854382186 0.1118030743683895 1.0 1.0 8 Q9UBX3 1 +Organic hydroxy compound catabolic process 0.6022390344570522 1.5845259340494275 0.1130740847586979 1.0 1.0 11 Q8WTV0,P30837 2 +Heparan sulfate proteoglycan biosynthetic process 0.7224826808981886 1.5829026869703913 0.1134436462322869 1.0 1.0 5 Q99805 1 +Heparan sulfate proteoglycan metabolic process 0.7224826808981886 1.5829026869703913 0.1134436462322869 1.0 1.0 5 Q99805 1 +Proteoglycan biosynthetic process 0.7224826808981886 1.5829026869703913 0.1134436462322869 1.0 1.0 5 Q99805 1 +Endochondral bone morphogenesis 0.7224088095920969 1.582588289078557 0.1135153344472947 1.0 1.0 5 P08133,O75844 2 +Response to osmotic stress 0.5190450357383136 1.5783030052990696 0.114496015837942 1.0 1.0 20 Q9BPX6,Q8TDW0,P08183,P30536 4 +Positive regulation of toll like receptor signaling pathway 0.7208679933966898 1.5760290670090231 0.1150191045921507 1.0 1.0 5 P41440 1 +Modification of synaptic structure 0.6839937502693763 1.5698017450543091 0.1164612414885823 1.0 1.0 7 O00264,Q9UQB8 2 +Cellular hormone metabolic process 0.5151968005944183 1.5654611944174532 0.1174748095038518 1.0 1.0 19 P42892,Q9HB40,O94788 3 +Positive regulation of histone deacetylation 0.7174203154925927 1.5613423122030217 0.1184430052127756 1.0 1.0 5 O43823,Q9ULX6 2 +Peroxisomal transport 0.7172668318494339 1.5606881685780487 0.1185973441878029 1.0 1.0 5 P56589,P40855,O75381 3 +Response to l glutamate 0.7864439291659719 1.5590966555163317 0.1189735051278688 1.0 1.0 4 O95831 1 +Reticulophagy 0.7863097290065056 1.55856372790871 0.119099673648078 1.0 1.0 4 Q96HY6 1 +Regulation of necrotic cell death 0.5787099651383705 1.5542433724840743 0.1201263753378487 1.0 1.0 12 P00403,P30536 2 +3 utr mediated mrna stabilization 0.6802128113328229 1.552632669420609 0.1205109161803552 1.0 1.0 7 P98175,P07910,Q13151,Q15717 4 +Establishment of protein localization to mitochondrial membrane 0.5129441169721876 1.5505929679240098 0.1209992584209516 1.0 1.0 19 P62072,Q9Y276,Q9NS69,O14737,Q9Y584,Q9P0J0 6 +Interferon gamma production 0.6789943563605194 1.5470952051135147 0.1218402899964106 1.0 1.0 7 P10809,Q08722 2 +Positive regulation of interferon gamma production 0.7826048176428355 1.5438448843835686 0.1226259148441486 1.0 1.0 4 P10809 1 +Negative regulation of release of cytochrome c from mitochondria 0.711577373973613 1.5434908146074924 0.1227117344460737 1.0 1.0 6 P02545,Q9Y255 2 +Regulation of response to extracellular stimulus 0.71184137924235 1.5375479804216243 0.1241591749345096 1.0 1.0 5 P80303 1 +Glial cell migration 0.5734041808548389 1.5250250124986484 0.1272528590772619 1.0 1.0 12 Q96G23,Q9NQC3,P30536 3 +Cartilage development 0.5633696186252674 1.522400390397523 0.1279087870804134 1.0 1.0 13 O75844,Q15043,Q92896,P08133,Q96HY6 5 +Protein refolding 0.5900699204935876 1.519898189256219 0.1285365656381094 1.0 1.0 11 Q9UL15,P10809,P48723 3 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.7751742837081366 1.5142906158261693 0.129952147592689 1.0 1.0 4 P30536 1 +Sphingolipid metabolic process 0.5194160073247766 1.5132617008106763 0.1302131970076065 1.0 1.0 28 P07602,Q06136,O15121,Q99805,Q8NCC3 5 +Retinoic acid metabolic process 0.8815615930364002 1.5129544523468683 0.1302912288809121 1.0 1.0 3 O94788 1 +Proteoglycan metabolic process 0.7038378250930968 1.5102087784191387 0.1309901594412004 1.0 1.0 6 Q99805 1 +Transmembrane transport 0.4533571243693268 1.5101739590312664 0.1309990415945039 1.0 1.0 218 Q99595,O60830,Q70HW3,P00403,Q9UDW1,Q8TDW0,Q9UHG3,Q8IXU6,P30825,P21796,Q8N4Q1,O43772,Q9H4I9,Q8TAD4,Q9NS69,O75844,Q03519,O75964,O95831,P00846,P08183,Q8WTV0,P17252,P52789,O75381,Q6NT16,P05771,Q9UBX3,Q6P4Q7,Q13423,P10809,Q9Y666,P23786,O15439,Q9Y584,Q9HD20,Q9Y6M7,P45880,P08133,P53985,P03915,Q8IYU8,P41440,Q15629,Q9BPX6,Q9H2V7,Q9BQT8 47 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.6367667498891878 1.5068151880006408 0.1318580354158627 1.0 1.0 8 O43765,P46379,Q7L5D6 3 +Deoxyribose phosphate metabolic process 0.5690949763860169 1.501254020689899 0.1332898724547404 1.0 1.0 12 Q9H773,P00813 2 +Protein lipid complex subunit organization 0.7017514519690251 1.501224996605515 0.1332973767427934 1.0 1.0 6 Q8WTV0,P17252 2 +Histone threonine phosphorylation 0.7712544138163279 1.498682228238328 0.1339560892868998 1.0 1.0 4 P17252 1 +Fatty acid transport 0.5383967410712022 1.4980913747976368 0.1341095117270356 1.0 1.0 15 P33121,O14975,O43772,P23786 4 +Purine ribonucleoside salvage 0.7023119477517044 1.4968272038503825 0.1344382258274064 1.0 1.0 5 Q13126 1 +Nucleoside salvage 0.7023119477517044 1.4968272038503825 0.1344382258274064 1.0 1.0 5 Q13126 1 +Protein insertion into er membrane 0.5587698400203654 1.4963430128079698 0.134564291717913 1.0 1.0 13 Q15629,O43765,P49069,Q7L5D6,P46379 5 +Nuclear pore organization 0.5658128331908782 1.4831252272752309 0.1380411425841106 1.0 1.0 12 Q7Z3B4,Q8NFH5,P12270,Q8WUM0,Q9BTX1,Q8N1F7,Q9NQC3,P57740 8 +Respiratory chain complex iv assembly 0.6647491350805333 1.4821996356505889 0.1382871835068166 1.0 1.0 7 Q9Y2R0,Q15070,Q9Y276 3 +Triglyceride metabolic process 0.6315451703076121 1.4815243165820593 0.1384669100489333 1.0 1.0 8 Q96N66,Q8WTV0 2 +Aminoglycan catabolic process 0.6984823767700896 1.4804370096468855 0.1387566593471554 1.0 1.0 5 P54802,P15586 2 +Glycosaminoglycan catabolic process 0.6984823767700896 1.4804370096468855 0.1387566593471554 1.0 1.0 5 P54802,P15586 2 +Glyoxylate metabolic process 0.8725634748667159 1.4793783134640022 0.1390392328696768 1.0 1.0 3 P48735 1 +Regulation of nuclear cell cycle dna replication 0.8717381535777907 1.4762969943941135 0.1398641806632365 1.0 1.0 3 P46100 1 +Autophagosome membrane docking 0.7650130548302893 1.473806813074426 0.1405336134037043 1.0 1.0 4 P56962,Q96GC9,O95721 3 +Intracellular lipid transport 0.5629775680405505 1.467449080183879 0.142253931437315 1.0 1.0 12 O15118,O43772,P23786 3 +Mitochondrial cytochrome c oxidase assembly 0.6927481279870149 1.4624028579723487 0.1436308467303391 1.0 1.0 6 Q9Y2R0,Q15070,Q9Y276 3 +Release of cytochrome c from mitochondria 0.532251289816683 1.461192190874072 0.1439627055123833 1.0 1.0 15 Q9Y255,Q3ZCQ8,O14737,P02545,Q9Y3B8,Q9H3K2 6 +Negative regulation of fatty acid biosynthetic process 0.7595524644904122 1.452021487261379 0.1464956307352514 1.0 1.0 4 O75477 1 +Negative regulation of glial cell proliferation 0.8641538147581389 1.4479695622511326 0.1476255633183965 1.0 1.0 3 P30536 1 +Ceramide metabolic process 0.4966602700286772 1.4427219042374428 0.1490988262717354 1.0 1.0 19 Q99805,Q8NCC3,O15121 3 +Primary alcohol metabolic process 0.4962093619937847 1.4397258643678297 0.1499449728119861 1.0 1.0 19 Q9BY49,P30837,O94788,Q6NUM9,Q9Y394,P51648 6 +Hydrogen peroxide metabolic process 0.607471676674304 1.439438379671404 0.1500263569131901 1.0 1.0 9 P00403 1 +Lipopolysaccharide mediated signaling pathway 0.6220314475282585 1.435334901062299 0.1511916868722789 1.0 1.0 8 Q8WTV0 1 +Protein hexamerization 0.6853990402003889 1.4306523562929327 0.1525298741979814 1.0 1.0 6 Q8TDW0,O60701 2 +Regulation of protein export from nucleus 0.5047316439954737 1.4303348547550094 0.1526209357192693 1.0 1.0 17 P50402,P12270,P17252,Q9Y3B8,Q14012 5 +Purine deoxyribonucleotide metabolic process 0.7539732410459846 1.4297437517169014 0.1527905781385452 1.0 1.0 4 P00813 1 +Cartilage development involved in endochondral bone morphogenesis 0.7538121605199976 1.429100291681722 0.1529754096991293 1.0 1.0 4 P08133,O75844 2 +Anion transport 0.4014222524240203 1.428000077022035 0.1532918363519737 1.0 1.0 72 Q15043,Q8TB61,P30825,Q8TDW0,Q9UHG3,P21796,Q6N075,P08183,Q9UBX3,P30536,Q9Y666,O15439,Q9Y6M7,O43865,P45880,P53985,P07602,Q99808,P41440,Q9BQT8 20 +Neural crest cell migration 0.7522642992289188 1.4229163977277766 0.1547603921025959 1.0 1.0 4 P08133 1 +Embryonic appendage morphogenesis 0.6515385322169089 1.4217807226502128 0.1550899175311428 1.0 1.0 7 O94788 1 +Membrane lipid biosynthetic process 0.499979708430678 1.41736005431363 0.1563776853184633 1.0 1.0 23 Q99805,Q06136,O15121,Q8NBX0 4 +Regulation of golgi organization 0.6029965932882755 1.4170006545506533 0.1564827361023335 1.0 1.0 9 Q5VU43 1 +Serine transport 0.7506527415143622 1.4164766504154198 0.1566359958271665 1.0 1.0 4 Q15758,Q9H9B4,Q96NB2 3 +Protein processing 0.5037563534332516 1.413130149281051 0.1576174599171393 1.0 1.0 40 Q8TAD4,Q15392,Q8TCT9,O75844,Q5JRX3,O75976,Q92896,P17252,P42892,Q96F07,Q10713 11 +Reactive oxygen species biosynthetic process 0.5863965595769702 1.412970487414608 0.1576644018464674 1.0 1.0 10 P00403 1 +Anion transmembrane transport 0.4981268331512724 1.4082710669572418 0.1590508195986573 1.0 1.0 44 Q9Y666,P41440,O15439,P30825,Q8TDW0,Q9UHG3,P08183,P45880,Q9BQT8,P21796,P53985,Q9UBX3 12 +Outer mitochondrial membrane organization 0.6812692742513876 1.4066051225137333 0.1595445132769684 1.0 1.0 5 Q9NS69 1 +Maintenance of sister chromatid cohesion 0.6479075405755876 1.4051384484194174 0.1599801129288216 1.0 1.0 7 P41227,P46100,Q9Y6X3 3 +Regulation of histone h3 k9 trimethylation 0.6791956996544769 1.4038126899577708 0.1603746341395275 1.0 1.0 6 P46100 1 +Histone h3 k9 trimethylation 0.6791956996544769 1.4038126899577708 0.1603746341395275 1.0 1.0 6 P46100 1 +Regulation of histone deacetylation 0.6465801403909582 1.399050864277719 0.1617977307175666 1.0 1.0 7 O43823,Q9ULX6 2 +Mitochondrion distribution 0.7456586315795432 1.396511886977898 0.162560403557094 1.0 1.0 4 O75153 1 +Mitochondrial electron transport ubiquinol to cytochrome c 0.6788187785353407 1.3960751564545693 0.1626918641599892 1.0 1.0 5 Q9UDW1,P47985,O14949 3 +Bone growth 0.8499184339314781 1.3947556675830002 0.1630895317089487 1.0 1.0 3 P08133,O75844 2 +Growth plate cartilage development 0.8499184339314781 1.3947556675830002 0.1630895317089487 1.0 1.0 3 P08133,O75844 2 +Vitamin transport 0.6452238282016879 1.3928287620401445 0.163671578635125 1.0 1.0 7 Q8WTV0 1 +Xenobiotic transport 0.6765732042292651 1.3924560898957763 0.163784329568102 1.0 1.0 6 O15439,P08183 2 +Endothelial cell proliferation 0.49039375561959 1.387575354776524 0.1652663903894944 1.0 1.0 20 Q8WTV0,P57105,O94788,P17252 4 +Mitochondrial protein processing 0.6743749967327444 1.3829325386445974 0.1666855520699099 1.0 1.0 6 Q10713 1 +Regulation of syncytium formation by plasma membrane fusion 0.6757219302343221 1.3827618405671882 0.1667379031118425 1.0 1.0 5 Q14012,P41440 2 +Positive regulation of syncytium formation by plasma membrane fusion 0.6757219302343221 1.3827618405671882 0.1667379031118425 1.0 1.0 5 Q14012,P41440 2 +Vitamin transmembrane transport 0.6738375870791242 1.3806036760503004 0.1674008524539552 1.0 1.0 6 Q8WTV0 1 +Mitochondrial fusion 0.5279663677251654 1.374901473494486 0.169161992405439 1.0 1.0 14 Q9Y6C9,Q99536,Q9Y4W6,Q8IWA4,Q9NX63,Q9GZY8 6 +Purine deoxyribonucleoside triphosphate metabolic process 0.8445882827473989 1.3748204029911573 0.1691871310562676 1.0 1.0 3 P00813 1 +Porphyrin containing compound metabolic process 0.4839162596999675 1.3724115019784344 0.1699353715039762 1.0 1.0 18 P22830,P30519,O00264,Q9UII2,P30536 5 +Glycosyl compound catabolic process 0.5773037666808523 1.365810563339498 0.1719984299865897 1.0 1.0 10 Q9NUJ1,P00813 2 +Mitochondrion organization 0.4230530454804209 1.364407561629358 0.1724393293466657 1.0 1.0 186 Q99595,O75431,O60830,Q5JRX3,Q96CV9,Q5HYI7,Q9Y3B8,Q9UII2,Q9Y6M9,Q9NX63,P21796,Q8N4Q1,Q7Z3C6,P55786,Q13505,P62072,Q9NS69,Q8N4H5,O96000,O43676,O95831,P51572,P52789,Q9Y2R0,Q10713,P30536,Q16706,P10809,Q99536,O75153,O14737,Q9Y584,Q69YU5,P02545,P45880,P03915,Q9H061,Q9BUK6,Q96CU9,Q5U5X0,Q86Y39,Q6DKK2 42 +Negative regulation of atp dependent activity 0.6387214582782574 1.362973219497565 0.172890950900443 1.0 1.0 7 Q15070,P04637,Q9UII2 3 +Smad protein signal transduction 0.57620825927162 1.360121452836024 0.1737914933692097 1.0 1.0 10 Q8N1F7,Q9UIQ6,Q96PK6,P08670 4 +Very long chain fatty acid catabolic process 0.7363470968161648 1.3592577672500878 0.1740649217028531 1.0 1.0 4 Q15067,O14975 2 +Blood vessel endothelial cell migration 0.4872589195853937 1.3538862012912265 0.1757726864700974 1.0 1.0 21 P42785,Q8WTV0 2 +Necrotic cell death 0.503759318171064 1.3528710189294266 0.1760968393947311 1.0 1.0 16 P00403,P30536 2 +Regulation of amyloid beta clearance 0.7346783305720779 1.3525777878997498 0.1761905524762386 1.0 1.0 4 Q16850,Q07954 2 +Atp biosynthetic process 0.4825430577240647 1.3487277261905586 0.1774244364516741 1.0 1.0 19 P00403,P00846 2 +Mitochondrial respiratory chain complex assembly 0.4941949935346317 1.3479058323310091 0.1776886719815005 1.0 1.0 41 Q5U5X0,Q86Y39,Q6DKK2,Q8N183,O96000,O43676,O95831,Q69YU5,Q9P0J0,Q9Y6M9,Q8N4Q1,Q9Y2R0,P03915,Q9H061,Q96CU9 15 +Cholesterol storage 0.8370210379186761 1.34651316099573 0.1781370788482583 1.0 1.0 3 Q8WTV0 1 +Regulation of dna methylation 0.6330125487266896 1.336728128764449 0.1813113966894137 1.0 1.0 7 Q8NB78,O75844 2 +Interleukin 12 production 0.6648812564111625 1.3361119083034338 0.1815126982766586 1.0 1.0 5 P10809 1 +Post translational protein modification 0.5553902550119331 1.334327713250261 0.1820964789900485 1.0 1.0 11 O60725,Q9HA64,Q32P28,O75718 4 +Lysine metabolic process 0.7294395215746241 1.3316015239585208 0.1829911638995831 1.0 1.0 4 Q9BQT8 1 +Amyloid precursor protein metabolic process 0.4852335409192477 1.3283411264632157 0.1840654391450686 1.0 1.0 22 Q9NQX7,Q15392,P35610,O95197,Q13464,Q92542,Q12959,Q96IZ0,Q9NY61,P49755,Q9NQC3 11 +Cellular copper ion homeostasis 0.7279236222565617 1.325530453422587 0.1849952757269859 1.0 1.0 4 O60826,P35670 2 +Cellular response to molecule of bacterial origin 0.4912029972793032 1.3233356266425838 0.1857237889428251 1.0 1.0 27 O43823,P11802,Q8WTV0,P17252,P08670,P30536 6 +Regulation of protein folding 0.7273413984478208 1.3231985429889106 0.1857693604240575 1.0 1.0 4 O14737,Q9UL15 2 +Cation transmembrane transport 0.3752197953501097 1.3231100729845076 0.1857987753887353 1.0 1.0 124 Q70HW3,P00403,Q9UDW1,P30825,P21796,O43772,Q9H4I9,Q8TAD4,O75964,P00846,P17252,Q6P4Q7,Q13423,Q9Y666,Q9HD20,P08133,P03915,Q8IYU8,Q9BPX6 19 +Cristae formation 0.5980783226767246 1.3184946787850385 0.1873381051956859 1.0 1.0 8 Q5XKP0,Q9NX63,Q9Y4W6,Q16891 4 +Pyrimidine deoxyribonucleotide metabolic process 0.6604200561170015 1.3168968119250948 0.1878732152812818 1.0 1.0 5 Q9H773,P78549 2 +Mrna transport 0.3746916447846273 1.3124747162608574 0.1893600115169391 1.0 1.0 75 P84103,Q96PU8,P82979,Q08J23,P41208,Q9BTX1,P61970,Q8NFH5,Q8TD16,Q86U42,Q07955,P51991,P22626,Q9ULX6,Q92945,P12270,Q86V81,Q53F19,Q8N1F7,Q12769,Q8NFH4,Q16629,Q9Y6M1,P09651 24 +Regulation of cell adhesion mediated by integrin 0.5963502303286375 1.3100394797798527 0.190182480182079 1.0 1.0 8 P00813,P46108 2 +Retinol metabolic process 0.5962120719139248 1.3093633706850123 0.1904112929805408 1.0 1.0 8 Q9Y394,O94788,Q6NUM9 3 +Negative regulation of catabolic process 0.3524376395503318 1.3074899911546385 0.1910463519602778 1.0 1.0 98 Q9P275,P10619,Q15717,Q16850,P85037,Q9UL15,Q08J23,Q14103,O43765,Q13151,P08621,P67809,Q99729,Q96KB5,O60506,Q92804,P30536,P49069,Q14011,Q96HY6,P46379,Q08379,P35637,Q9Y2W1,P98175,P07910,O15118,Q92530,Q96JB5 29 +Response to increased oxygen levels 0.5657160398315508 1.3055647115622706 0.1917006273680335 1.0 1.0 10 P00846,Q8N511 2 +Syncytium formation 0.6261635363690197 1.3052060107032764 0.1918227080263324 1.0 1.0 7 Q14012,P41440 2 +Cellular modified amino acid catabolic process 0.6561976492450592 1.3040506099036908 0.1922163271489059 1.0 1.0 6 Q9UHG3,Q9NRN7 2 +Cell adhesion mediated by integrin 0.5787815003051429 1.295140137279888 0.1952718910031041 1.0 1.0 9 P00813,P46108 2 +Collagen fibril organization 0.5784859621384019 1.2936489120962804 0.1957867193041806 1.0 1.0 9 Q92791,Q96AY3,O75718 3 +Protein oxidation 0.8225752938241352 1.2924754366190805 0.1961925470955627 1.0 1.0 3 Q8N4Q1 1 +Positive regulation of erad pathway 0.8199021207177757 1.2824781558421572 0.1996749629678971 1.0 1.0 3 P46379,P51572 2 +Purine deoxyribonucleoside monophosphate metabolic process 0.8197766169991947 1.2820088211628695 0.1998395518246842 1.0 1.0 3 P00813 1 +Damp metabolic process 0.8197766169991947 1.2820088211628695 0.1998395518246842 1.0 1.0 3 P00813 1 +Crd mediated mrna stabilization 0.5756581693928284 1.27937653758313 0.2007644919373756 1.0 1.0 9 O60506,P67809 2 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5756581693928284 1.27937653758313 0.2007644919373756 1.0 1.0 9 O60506,P67809 2 +Attachment of mitotic spindle microtubules to kinetochore 0.6203998191787546 1.2786527238854566 0.2010193746487716 1.0 1.0 7 Q9BZD4,Q96DB5,Q96GD4 3 +Response to salt 0.7140992167101969 1.270146349578759 0.2040325041504995 1.0 1.0 4 P07196,P09651,Q14103 3 +Alcohol metabolic process 0.3709383955910439 1.2669518646091311 0.2051725019861006 1.0 1.0 75 P34913,Q15126,Q16850,O75477,O94788,Q6NUM9,Q14534,P37268,P35610,P30837,Q8WTV0,O75874,P51648,Q10713,P48735,Q15392,P16435,Q9HBH5,Q9Y394,Q9BY49,O15118 21 +Chromosome condensation 0.4777478483186749 1.2663716926659845 0.2053800405429207 1.0 1.0 23 O43823,Q9HD42,Q9ULX6,P84243,P07305,Q8IY18,P10412,O95831,P16402,P53350 10 +Nuclear pore complex assembly 0.5729607921620726 1.2657561527826997 0.2056003976557323 1.0 1.0 9 Q9NQC3,Q9BTX1,P12270 3 +Regulation of calcium ion import 0.8131118314489183 1.2570901038019924 0.2087210102233958 1.0 1.0 3 P21796 1 +Signaling receptor ligand precursor processing 0.7107780137381899 1.2568385201777612 0.2088121144723986 1.0 1.0 4 P42892,Q8TAD4 2 +Regulation of platelet derived growth factor receptor signaling pathway 0.8123980424143555 1.2544220132445432 0.2096886554588002 1.0 1.0 3 O14964,Q07954 2 +Pattern recognition receptor signaling pathway 0.4822432259945748 1.254372792100191 0.2097065371172504 1.0 1.0 28 Q9NPR9,O43657,P10809,P41440 4 +Microtubule anchoring 0.555454745162651 1.2521069280447692 0.2105309035595459 1.0 1.0 10 O95684,O75381 2 +Ion transmembrane transport 0.3967992305134681 1.2485148612620962 0.2118425694820584 1.0 1.0 160 Q70HW3,P00403,Q9UDW1,Q8TDW0,Q9UHG3,P30825,P21796,O43772,Q9H4I9,Q8TAD4,O75844,O75964,P00846,P08183,P17252,Q9UBX3,Q6P4Q7,Q13423,Q9Y666,O15439,Q9HD20,Q9Y6M7,P45880,P08133,P53985,P03915,Q8IYU8,P41440,Q9BPX6,Q9BQT8 30 +Monocarboxylic acid transport 0.5834153808199158 1.246666137038732 0.2125199402397544 1.0 1.0 8 O15439,P53985,P28288,P04083 4 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.5148901139438857 1.2460763246593285 0.2127363757260263 1.0 1.0 13 Q9NR28,P10809,P61604,O95831 4 +Organophosphate ester transport 0.4818736707189855 1.24596040512536 0.2127789318616484 1.0 1.0 29 Q99808,P41440,O15439,Q8TB61,Q8TDW0,P08183,Q8WTV0,Q14108,Q7Z3C6,Q08722 10 +Platelet derived growth factor receptor beta signaling pathway 0.8099009625810951 1.2450893165455923 0.2130989207418814 1.0 1.0 3 Q07954 1 +Chloride transport 0.5140194617880476 1.2410893044316909 0.2145727602169422 1.0 1.0 13 Q9UHG3,P08183 2 +Morphogenesis of embryonic epithelium 0.4703222904937941 1.2397709247056337 0.2150601353075205 1.0 1.0 21 P17252,O94788 2 +Purine nucleoside metabolic process 0.5674940519263061 1.2381352958590812 0.2156658983722172 1.0 1.0 9 Q13126,O60725,P00813 3 +Negative regulation of gliogenesis 0.6421299090310353 1.2380513654881122 0.2156970155073965 1.0 1.0 5 P30536 1 +Regulation of mrna catabolic process 0.3997372080257395 1.2372241493477292 0.2160038784076479 1.0 1.0 69 Q13868,Q15717,Q969T7,Q15024,Q13151,P67809,Q99729,P17252,O60506,Q92804,Q14011,Q92945,Q9HBH5,Q9HCE1,P35637,Q9Y2W1,P98175,P07910,P08670 19 +Amyloid precursor protein catabolic process 0.473861891413565 1.2318646045664663 0.2179996653061224 1.0 1.0 17 O95197,Q15392 2 +Endoplasmic reticulum calcium ion homeostasis 0.7043598208464256 1.2311227367323938 0.2182769629441634 1.0 1.0 4 Q96A33,P51572 2 +Mitotic nuclear membrane disassembly 0.702283093966933 1.2228029148620738 0.2214041442637198 1.0 1.0 4 P05771,P17252 2 +Membrane protein proteolysis 0.5187207910318679 1.2213156920610204 0.2219665142602358 1.0 1.0 12 Q16740,P38159,Q8TCT9 3 +Macromolecule depalmitoylation 0.636975192613678 1.2204578417655505 0.2222913618172817 1.0 1.0 6 Q9NUJ1 1 +Negative regulation of posttranscriptional gene silencing 0.63792419295772 1.2199140896093574 0.2224974440559077 1.0 1.0 5 Q15717,P04637,O75844 3 +Endocrine system development 0.5181108659261775 1.2179112920783517 0.2232576846104046 1.0 1.0 12 O94788 1 +Antigen processing and presentation of endogenous peptide antigen 0.6069226008976302 1.2164925813313447 0.2237973353889319 1.0 1.0 7 P04439,Q03519 2 +Antigen processing and presentation of endogenous antigen 0.6069226008976302 1.2164925813313447 0.2237973353889319 1.0 1.0 7 P04439,Q03519 2 +Peptidyl lysine trimethylation 0.464181302484538 1.2117635004938705 0.2256029237433285 1.0 1.0 20 P16403,Q03164,P10412,Q9GZS3,P46100,P02545,P16402,Q6UXN9 8 +Protein targeting to peroxisome 0.6968945838738 1.2012192891172773 0.2296661489323428 1.0 1.0 4 P56589,O75381 2 +Hydrogen peroxide biosynthetic process 0.7980237637284826 1.2007308377279156 0.2298556279051253 1.0 1.0 3 P00403 1 +Ribonucleoside triphosphate biosynthetic process 0.4735348857830278 1.2005539158249947 0.2299242864777135 1.0 1.0 27 P00403,O75964,P00846 3 +Regulation of phospholipid metabolic process 0.5451141055825542 1.1981648214298453 0.2308528575870445 1.0 1.0 10 Q8WTV0 1 +Mitochondrial ribosome assembly 0.6959067605730194 1.1972633478531851 0.2312039255669269 1.0 1.0 4 Q567V2 1 +Gastrulation with mouth forming second 0.6954960835509213 1.1956187901267925 0.2318453554316235 1.0 1.0 4 Q4VCS5,O60701,Q99496 3 +Gdp metabolic process 0.6319767953098545 1.194266995442715 0.2323735437087477 1.0 1.0 5 Q14168,O14936,Q12959 3 +Positive regulation of release of cytochrome c from mitochondria 0.6309371386223984 1.1941830408418468 0.232406375527773 1.0 1.0 6 Q9GZY8,O14737,P04637 3 +Regulation of steroid metabolic process 0.4967691581879553 1.1914382224686222 0.233481595305363 1.0 1.0 14 P34913,Q9UHI6,O75477,P30536 4 +Iron ion homeostasis 0.4674905687053388 1.1907824291479152 0.2337390084678428 1.0 1.0 17 Q15904,Q9Y487,Q15043,P30519,Q8N511 5 +Detection of external biotic stimulus 0.7945208083135537 1.1876606383978268 0.2349671372342978 1.0 1.0 3 Q8WTV0 1 +Regulation of histone h3 k14 acetylation 0.7944978331574126 1.1875749357275205 0.2350009174273819 1.0 1.0 3 Q03164 1 +Positive regulation of leukocyte proliferation 0.477237979838971 1.1873782967525066 0.2350784367883622 1.0 1.0 16 P04439,P00813,P98172,P30825,P49366,P04083 6 +Antigen processing and presentation of exogenous peptide antigen 0.7931468335810844 1.1825359230696344 0.2369931204071849 1.0 1.0 3 Q9UIQ6 1 +Semaphorin plexin signaling pathway 0.6277771034700418 1.1804316007013014 0.237828599696714 1.0 1.0 6 P42892 1 +Inorganic ion transmembrane transport 0.3597465413737686 1.1787555840112467 0.2384955152364836 1.0 1.0 118 Q13423,Q8IYU8,Q8TAD4,P00403,O75964,P03915,P00846,Q9HD20,Q9UDW1,Q9UHG3,P17252,P08133,P21796,Q9UBX3,Q9H4I9 15 +Membrane lipid metabolic process 0.474492915474842 1.1775814299864122 0.238963516662338 1.0 1.0 36 P07602,Q06136,O15121,Q8NBX0,Q99805,Q8NCC3 6 +Golgi vesicle budding 0.6890449350364758 1.169792621746914 0.2420844335926408 1.0 1.0 4 Q8N6H7,Q9BVK6 2 +Copi coated vesicle budding 0.6890449350364758 1.169792621746914 0.2420844335926408 1.0 1.0 4 Q8N6H7,Q9BVK6 2 +Secondary alcohol metabolic process 0.4734244648519406 1.1691489011156184 0.2423436446316733 1.0 1.0 35 P34913,P48735,Q15392,Q15126,P37268,P35610,Q16850,O15118,O75477,Q8WTV0,O75874,Q14534 12 +Nls bearing protein import into nucleus 0.5386143666723561 1.1642378763097374 0.2443276246091277 1.0 1.0 10 P52292,Q8NFH5 2 +Neuron recognition 0.6871993144468145 1.162406987241509 0.245070186419912 1.0 1.0 4 Q9NQC3 1 +Regulation of muscle contraction 0.4542197578381827 1.1593601639343636 0.2463094074156946 1.0 1.0 19 P00813,P17252 2 +Chondrocyte differentiation 0.55144057093957 1.1569349194394505 0.2472989506802863 1.0 1.0 9 Q92896,Q15043,P08133 3 +Peroxisome fission 0.683213812539319 1.1464637073629629 0.2516033356742548 1.0 1.0 4 Q9GZY8,P40855 2 +Regulation of steroid biosynthetic process 0.5351031903561245 1.145907818575066 0.2518332958171747 1.0 1.0 10 Q9UHI6,O75477,P30536 3 +Protein localization to nuclear envelope 0.5916215306787023 1.145856230544917 0.251854644189776 1.0 1.0 7 Q5JTV8,P61970,P53350 3 +Calcium mediated signaling using intracellular calcium source 0.7831835739071069 1.1454102636822734 0.2520392486589378 1.0 1.0 3 P17252 1 +Regulation of response to food 0.99119373776908 1.142172226448939 0.2533824380519385 1.0 1.0 2 P80303 1 +Negative regulation of response to food 0.99119373776908 1.142172226448939 0.2533824380519385 1.0 1.0 2 P80303 1 +Regulation of appetite 0.99119373776908 1.142172226448939 0.2533824380519385 1.0 1.0 2 P80303 1 +Response to zinc ion 0.6198692412063062 1.1420780337836716 0.2534215851406083 1.0 1.0 5 P30536 1 +Skeletal muscle cell differentiation 0.5337861857966253 1.139032374566408 0.2546896513194874 1.0 1.0 10 Q92841,O75446,P50402 3 +Lipoprotein localization 0.5899547408579344 1.138161000541994 0.2550532601878674 1.0 1.0 7 A6NIH7,O15260 2 +Lung alveolus development 0.7810604865213597 1.1375082046093794 0.2553258966955054 1.0 1.0 3 P00813 1 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6799068200579282 1.1332411841180654 0.2571129835255381 1.0 1.0 4 P05771 1 +Apoptotic mitochondrial changes 0.4671532093542183 1.12855006226568 0.2590876869112499 1.0 1.0 32 Q9Y255,P10809,Q3ZCQ8,O14737,P02545,P45880,Q8IXI1,Q9UII2,Q9Y3B8,P52789,Q9H3K2 11 +Positive regulation of pattern recognition receptor signaling pathway 0.5587999320105895 1.1257926814121275 0.2602532826795234 1.0 1.0 8 P41440 1 +Positive regulation of leukocyte cell cell adhesion 0.4582763791804072 1.1226709871246123 0.2615772543246464 1.0 1.0 24 P10809,P00813,P98172,P30825,Q08722 5 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.6769029685975291 1.1212365267168 0.2621871955424435 1.0 1.0 4 Q8WUM0 1 +Regulation of phospholipid catabolic process 0.7764373655827165 1.1203137090396211 0.2625801021352005 1.0 1.0 3 Q8WTV0 1 +Glial cell proliferation 0.6139506759873645 1.1202804494247278 0.2625942706150652 1.0 1.0 6 P30536 1 +Protein geranylgeranylation 0.6758291130900702 1.1169464042173969 0.2640172418551452 1.0 1.0 4 P53609 1 +Cytosolic calcium ion transport 0.4610753700330033 1.113914456780119 0.2653158867729264 1.0 1.0 27 P21796,Q8IYU8,P17252,Q9H4I9 4 +Transition metal ion transport 0.4917262570660475 1.1133361843785607 0.2655640714200569 1.0 1.0 13 Q9HD20,Q8TAD4,O15173 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.58439983014802 1.1125182942788834 0.2659153688028177 1.0 1.0 7 Q96CV9,P52789 2 +Response to mitochondrial depolarisation 0.58439983014802 1.1125182942788834 0.2659153688028177 1.0 1.0 7 Q96CV9,P52789 2 +Pyrimidine nucleotide catabolic process 0.7741754952943253 1.111907991142966 0.266177712480613 1.0 1.0 3 Q9H773 1 +Phosphatidylcholine catabolic process 0.9814090019569468 1.108734509395218 0.2675447300824887 1.0 1.0 2 Q8WTV0 1 +Negative regulation of mitochondrion organization 0.4822821950245447 1.1061068700535552 0.2686802655018954 1.0 1.0 14 P02545,Q9Y255,Q99536,P30536 4 +Protein localization to phagophore assembly site 0.6110291471365015 1.104012632435803 0.2695876579289016 1.0 1.0 5 Q7Z3C6 1 +Positive regulation of cysteine type endopeptidase activity 0.4569567515299967 1.1033420759237345 0.2698786409105111 1.0 1.0 25 O00291,P10809,O14737,O95831,P51572,P61604,Q9P0J0,Q9NR28,Q96F07 9 +Triglyceride biosynthetic process 0.6719605517463214 1.101498175550078 0.270679898104299 1.0 1.0 4 Q8WTV0 1 +Negative regulation of lipase activity 0.7712887438825404 1.101186912696287 0.2708153164295237 1.0 1.0 3 Q99523,P16435 2 +Icosanoid transport 0.7709624796084665 1.0999757053635806 0.2713427073130749 1.0 1.0 3 O15439,P04083 2 +Tetrapyrrole metabolic process 0.4494965745024314 1.099242496523832 0.2716623069688648 1.0 1.0 21 P30519,O00264,Q9UII2,P30536 4 +Organic hydroxy compound transport 0.4625000097674771 1.0991077829914586 0.2717210555025995 1.0 1.0 31 Q9H4L5,P35610,O15439,Q86Y82,O15118,Q8WTV0,P53985,P28288,P30536 9 +Positive regulation of cell population proliferation 0.3470568618490137 1.0951690366961655 0.2734425880454056 1.0 1.0 110 O95684,P00813,Q14004,P22392,P98172,P43307,P30825,P17252,O94788,P43490,P55209,Q96HY6,Q9NQC3,P30536 14 +Nucleoside triphosphate metabolic process 0.4579629709420583 1.0918831748402316 0.2748844539501389 1.0 1.0 44 Q9H773,P00813,P00403,O75964,P22392,P00846 6 +Negative regulation of lymphocyte mediated immunity 0.6692227637627248 1.0905725130676331 0.2754610298664395 1.0 1.0 4 P46108 1 +Nucleoside metabolic process 0.4415677648972441 1.0903889527318706 0.2755418461077707 1.0 1.0 18 Q13126,O60725,P00813 3 +Positive regulation of stem cell differentiation 0.6687530917769637 1.0886988284485877 0.2762867186134969 1.0 1.0 4 Q13610,Q9Y6C9 2 +Regulation of mitochondrial membrane permeability 0.4792273028752986 1.08812361130833 0.2765405415092141 1.0 1.0 14 P45880,P52789 2 +Negative regulation of amyloid fibril formation 0.6072249205867584 1.087647040371296 0.276750955713831 1.0 1.0 5 O15212 1 +Regulation of amyloid fibril formation 0.6072249205867584 1.087647040371296 0.276750955713831 1.0 1.0 5 O15212 1 +Lipid localization 0.371111185252202 1.08115431383482 0.2796284765368431 1.0 1.0 72 O14975,P33121,Q14108,Q14534,Q7Z3C6,O43772,Q9Y255,P35610,P08183,Q8WTV0,P30536,Q9H4L5,P23786,O15439,O15260,P07602,Q9H2V7,O15118,Q86Y82 19 +Negative regulation of protein kinase activity by regulation of protein phosphorylation 0.6051770612595418 1.0788418990874653 0.2806582131489761 1.0 1.0 5 Q96JB5 1 +Histone h3 k9 acetylation 0.6659214436446153 1.0774065359709528 0.2812986854574251 1.0 1.0 4 Q03164 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.7647634584012958 1.0769833858827385 0.2814876881178372 1.0 1.0 3 O43865,Q96GC9 2 +Tetrapyrrole biosynthetic process 0.4852817160343159 1.0764283124292493 0.2817357458128318 1.0 1.0 13 P50336,P22830,O00264,Q9UII2,P30536 5 +Cellular response to reactive nitrogen species 0.5765738140891802 1.0764076233195687 0.2817449944692234 1.0 1.0 7 P46108,O95831 2 +Response to nitric oxide 0.5765738140891802 1.0764076233195687 0.2817449944692234 1.0 1.0 7 P46108,O95831 2 +Regulation of muscle organ development 0.575978274147766 1.0736608114558632 0.2829747314735251 1.0 1.0 7 P41440 1 +Golgi ribbon formation 0.6626607954397307 1.0644127495290543 0.2871417606136774 1.0 1.0 4 Q08379 1 +Neuron projection guidance 0.4420883682252266 1.0633514831594992 0.2876225860264929 1.0 1.0 20 P42892,O00264,O15031 3 +Response to ischemia 0.5189821272587707 1.0617771126418172 0.2883368824371386 1.0 1.0 10 O95831 1 +Kidney morphogenesis 0.6007399209618879 1.059776198506934 0.2892464274915602 1.0 1.0 5 Q12959,P80723,O75844 3 +Glycoprotein biosynthetic process 0.448159146956669 1.0585602363981848 0.2898001041680338 1.0 1.0 48 P04843,P04844,Q92542,Q96IZ0,Q9NY61,Q10472,O60701,Q9Y5P6,P35610,Q9BT22,Q86SF2,Q8NAT1,Q99805,O94923,Q16706,Q9NQX7,Q7LGA3,O60502,Q2TAA5,Q08379,P46977,O15118,Q8TCJ2 23 +Antiviral innate immune response 0.6000652954619655 1.0568790683526874 0.2905667824977609 1.0 1.0 5 Q99623,Q9NVI7,Q92667,Q9H078 4 +Negative regulation of nitric oxide metabolic process 0.6606907858743898 1.0565673673387237 0.2907090801644791 1.0 1.0 4 P30536 1 +Regulation of reactive oxygen species metabolic process 0.4560749498570511 1.0534012818937768 0.2921571169258765 1.0 1.0 31 P00403,P42785,P52789 3 +Chromosome organization involved in meiotic cell cycle 0.455668246933554 1.0526741960916897 0.2924903389152322 1.0 1.0 16 Q92791,P46100 2 +Cellular response to cold 0.757996224484735 1.0519321685113798 0.2928306717514362 1.0 1.0 3 P17252 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4883304446398775 1.0517187211298074 0.2929286191524594 1.0 1.0 12 P67809 1 +Hormone metabolic process 0.4550638466229699 1.0513668038666748 0.2930901560617855 1.0 1.0 30 Q8TAD4,O75844,P16435,Q9HB40,Q9HBH5,Q969M3,O94788,Q6NUM9,P42892,Q9Y394,P30536 11 +Modification of postsynaptic structure 0.5978768234775008 1.050452884916616 0.2935099419502445 1.0 1.0 6 Q9UQB8 1 +Cellular response to estrogen stimulus 0.5982855324697456 1.049238222940448 0.2940684907092707 1.0 1.0 5 Q969T9,Q8IZL8 2 +Regulation of body fluid levels 0.4469210821337401 1.0484278797833766 0.2944415140800536 1.0 1.0 48 Q13505,Q9UNN8,P00813,P00403,Q9Y3B8,P52789 6 +Ether metabolic process 0.542977839158074 1.0480722421165267 0.2946053240400714 1.0 1.0 8 P07099 1 +Glycoside catabolic process 0.5967542253389658 1.0455828875273114 0.2957536534195051 1.0 1.0 6 Q9NUJ1 1 +Modification of postsynaptic actin cytoskeleton 0.6566620390645483 1.0405363110233523 0.2980908032604072 1.0 1.0 4 Q9UQB8 1 +Response to muramyl dipeptide 0.7540305385417926 1.0372778941541836 0.2996063649963143 1.0 1.0 3 P08670 1 +Sulfate transport 0.7539967373572416 1.0371530776304174 0.2996645219535345 1.0 1.0 3 Q9H0H5,Q9UBX3 2 +Negative regulation of nf kappab transcription factor activity 0.4619658202325801 1.0360507057196224 0.3001784875499156 1.0 1.0 15 P19474,Q96RT1,O60826,P09525,Q96JB5 5 +Membrane disassembly 0.5666943346366997 1.0308696051368558 0.3026019718024109 1.0 1.0 7 P05771,P53350,P17252 3 +Neural tube development 0.4411842284984534 1.0299674962882974 0.3030252639691284 1.0 1.0 22 P17252,O94788 2 +Regulation of lipopolysaccharide mediated signaling pathway 0.7504164570900735 1.0239410667450717 0.3058631116377421 1.0 1.0 3 P17252 1 +L serine transport 0.7504078303425786 1.0239092535784255 0.3058781390727361 1.0 1.0 3 Q15758,Q9H9B4 2 +Protein export from nucleus 0.4486635608859306 1.019691905693579 0.3078746017133826 1.0 1.0 28 P50402,P61970,P12270,O43865,Q9Y3B8,P17252,Q14012 7 +Regulation of smad protein signal transduction 0.5911965251013322 1.0188388684021774 0.3082794696568376 1.0 1.0 5 Q8N1F7,Q07954 2 +2 oxoglutarate metabolic process 0.53693521660508 1.018418860384038 0.3084789428920209 1.0 1.0 8 P48735 1 +Leukotriene metabolic process 0.6510415099080966 1.0182033077829742 0.3085813478248562 1.0 1.0 4 Q14914,P09960 2 +Copper ion homeostasis 0.5908542055409924 1.0173724631251595 0.3089762765878725 1.0 1.0 5 O60826,P35670 2 +Positive regulation of reactive oxygen species metabolic process 0.4584363476903265 1.014716025082336 0.3102412129921976 1.0 1.0 15 P00403 1 +Histone h3 k27 trimethylation 0.7477977161500815 1.0142887246082537 0.3104450026892755 1.0 1.0 3 P16402,P10412 2 +Regulation of lipase activity 0.4957095254808844 1.012765739259747 0.311172068980313 1.0 1.0 11 P16435,P04083,Q99523,P50897,Q07954 5 +Glycolipid biosynthetic process 0.5352421253101332 1.0101150625321147 0.3124401665339804 1.0 1.0 8 Q8NBX0 1 +Sterol transport 0.4393490938936426 1.0050704830616404 0.3148629119346751 1.0 1.0 23 Q9H4L5,O15118,Q8WTV0,P30536 4 +Positive regulation of amyloid precursor protein biosynthetic process 0.7448613376835151 1.0034776064125197 0.3156304763031292 1.0 1.0 3 P35610,Q92542 2 +Keratinization 0.9500978473581176 1.0026221177006698 0.3160432200914131 1.0 1.0 2 Q9Y3B8 1 +Rna phosphodiester bond hydrolysis exonucleolytic 0.438222106644766 0.997426376995212 0.3185575934090119 1.0 1.0 23 Q15024,Q9Y3B8,Q9BQ61,Q13868 4 +Embryo development ending in birth or egg hatching 0.3453703820110867 0.9945031826368992 0.319977956731567 1.0 1.0 117 P00813,P23786,Q15293,P67809,Q96EK5,Q14978,Q96AY3,P17252,O94788,O15031,P42892,Q9NQC3,O43772,Q16706 14 +Nadp metabolic process 0.4368588725156587 0.9934852795410024 0.3204735206696889 1.0 1.0 17 Q13423,P48735 2 +Nucleobase containing compound transport 0.3378804536727814 0.9926757347871888 0.3208680037527778 1.0 1.0 108 P84103,Q96PU8,Q8TB61,Q8TDW0,Q08J23,P41208,Q9BTX1,Q08722,P61970,Q8NFH5,P67809,Q8TD16,Q86U42,Q07955,P51991,P22626,O15439,Q92945,P12270,Q53F19,Q8N1F7,Q12769,Q8NFH4,Q99808,P41440,Q16629,Q9Y6M1,P09651 28 +Regulation of transcription regulatory region dna binding 0.5182866088855475 0.9893056026830772 0.3225136436925977 1.0 1.0 9 Q96HY6,P30626,O75844 3 +Amide transport 0.4478142000854542 0.9878829336459334 0.3232099845804947 1.0 1.0 40 P07602,P41440,Q03519,O15439,P08183,P53985 6 +Negative regulation of natural killer cell mediated immunity 0.7396176953626141 0.984204961860589 0.3250147466276065 1.0 1.0 3 P46108 1 +Regulation of skeletal muscle cell differentiation 0.6393396520811548 0.9718455753118744 0.3311273787916622 1.0 1.0 4 Q92841,P17844 2 +Positive regulation of cell cell adhesion 0.4439453644118729 0.9673299192974896 0.3333791314439676 1.0 1.0 31 P10809,P00813,P41440,P98172,P30825,Q08722 6 +Regulation of fatty acid biosynthetic process 0.5521614398336744 0.9640442379824378 0.3350237473782596 1.0 1.0 7 P49748,O75477 2 +Cation transport 0.374822806099069 0.9634872122615364 0.3353030784949753 1.0 1.0 159 O95219,O14936,Q70HW3,P00403,Q9UDW1,P30825,P21796,O43772,O15173,Q9H4I9,Q8TAD4,O75844,O75964,P00846,P17252,P05771,P30536,Q6P4Q7,Q13423,Q9Y666,Q9HD20,Q9Y6M7,O43865,P08133,P03915,Q8IYU8,Q99808,Q9BPX6 28 +Negative regulation of response to external stimulus 0.4424031951472243 0.9621705163732334 0.3359639567855967 1.0 1.0 43 P28070,P00813,P46108,O14936,Q96G23,O43657,P80303,Q96KB5,Q9UMX5 9 +Organic acid transport 0.438716846416155 0.9584639023871744 0.3378288854806817 1.0 1.0 46 P23786,P41440,O15439,O14975,Q8TDW0,P08183,Q9BQT8,P53985,Q9UBX3,O43772 10 +Neurotransmitter uptake 0.5764765883460786 0.957850417900798 0.3381381914723023 1.0 1.0 6 P41440 1 +Dna templated transcription termination 0.5241649120629496 0.9558573988829108 0.3391442844754948 1.0 1.0 8 O95104 1 +Phosphatidylserine metabolic process 0.6338006559066771 0.9499784663152476 0.3421231943841412 1.0 1.0 4 Q8NCC3 1 +Proton transmembrane transport 0.4407801203839849 0.9495692344645668 0.3423311771730697 1.0 1.0 43 Q13423,Q8TAD4,P00403,P00846,Q9UDW1,P03915 6 +Walking behavior 0.6336180931325801 0.9492586586596868 0.3424890742226427 1.0 1.0 4 O15118 1 +Vacuolar acidification 0.5100708928609039 0.9479088933355996 0.3431758370972955 1.0 1.0 9 Q8N511 1 +Regulation of triglyceride metabolic process 0.9324853228962776 0.9436737194289604 0.3453364077163852 1.0 1.0 2 Q8WTV0 1 +Cellular response to increased oxygen levels 0.5477058856788872 0.9436104811199578 0.3453687342611884 1.0 1.0 7 Q8N511 1 +Lipid homeostasis 0.426016611178999 0.9413411290066672 0.3465300721348783 1.0 1.0 21 Q9Y6C9,P34913,P35610,O15254,O15260,O15118,Q8WTV0,Q15067,Q9NQC3 9 +Ceramide biosynthetic process 0.4818997294180112 0.9386613943790768 0.3479046204741129 1.0 1.0 11 O15121 1 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.9308545335942544 0.9382474212171646 0.3481172734156081 1.0 1.0 2 P42892 1 +Nucleobase containing small molecule catabolic process 0.5722274330495158 0.9378468438326016 0.348323123756217 1.0 1.0 5 P00813 1 +T cell mediated immune response to tumor cell 0.7268751476874715 0.9375679207690228 0.3484665035579426 1.0 1.0 3 P10809 1 +Gmp biosynthetic process 0.4664033271563946 0.9299116724322852 0.3524168189468937 1.0 1.0 12 P00813 1 +Nucleosome positioning 0.5064499482430131 0.9296969610571256 0.352528008374132 1.0 1.0 9 P07305,P16402,P10412 3 +Dendritic transport 0.5698516717001734 0.9293119721267684 0.3527274325217049 1.0 1.0 6 Q00577 1 +Pigment metabolic process 0.4340879824114929 0.926948420635017 0.3539533152041589 1.0 1.0 27 P00813,P22830,P34897,P30519,O00264,Q9UII2,P30536 7 +Regulation of endothelial cell migration 0.4339348220505494 0.9258928700876546 0.354501656990557 1.0 1.0 27 P42785,P17252,Q8WTV0 3 +Cellular iron ion homeostasis 0.4587462983022637 0.9250387568075784 0.3549457477650153 1.0 1.0 13 Q8N511,Q15904,Q15043,Q9Y487 4 +Histone h3 k4 trimethylation 0.4924765613106366 0.923945886976519 0.3555144903889771 1.0 1.0 10 P16403,Q03164,P10412,Q9GZS3,P16402 5 +Ephrin receptor signaling pathway 0.5427618547699862 0.9209736062249894 0.3570642071638541 1.0 1.0 7 P98172 1 +Regulation of cholesterol metabolic process 0.5678968075084978 0.9209055706809736 0.3570997299395357 1.0 1.0 6 P34913,O75477,P16435 3 +Reactive nitrogen species metabolic process 0.4159234384362082 0.9201389304264148 0.3575001626340808 1.0 1.0 18 Q08722,P30536,O43169,Q92945 4 +Regulation of heart rate 0.4642048495909004 0.9177545782115476 0.3587473669775116 1.0 1.0 12 P00813 1 +Negative regulation of glycoprotein metabolic process 0.7210440456769817 0.916330468893183 0.3594935918530013 1.0 1.0 3 Q9NQX7,Q9NY61 2 +Negative regulation of amyloid precursor protein catabolic process 0.5029916307037805 0.9123251414967524 0.3615975832251012 1.0 1.0 9 O95197 1 +Negative regulation of secretion 0.4212889145409591 0.9097219559828302 0.362969162098929 1.0 1.0 21 P00813,Q16836,Q16850 3 +Water homeostasis 0.5020149437784963 0.9074232912094006 0.3641829972867889 1.0 1.0 9 Q9Y3B8 1 +Peroxisome organization 0.4892667027564503 0.9073334608277492 0.3642304846734827 1.0 1.0 10 P56589,P28288,P40855,O75381 4 +Cellular response to biotic stimulus 0.4371097010451759 0.9065497139478486 0.3646449640558216 1.0 1.0 34 O43823,O75844,P11802,Q8WTV0,P17252,P08670,P30536 7 +Regulation of gliogenesis 0.46166338380564 0.9037173573818396 0.3661452928830464 1.0 1.0 12 P30536 1 +Circadian regulation of gene expression 0.4315650097550622 0.9029362407477288 0.3665597350615477 1.0 1.0 16 P43490 1 +Protein lipid complex assembly 0.5637965119449269 0.9020619380708153 0.3670239663832813 1.0 1.0 5 P17252 1 +Regulation of mrna export from nucleus 0.5633305372014792 0.9000886784703385 0.3680730605108635 1.0 1.0 5 Q08J23,P12270 2 +Peptidyl proline hydroxylation 0.5381818480345726 0.9000427042495467 0.368097525188418 1.0 1.0 7 Q13162,Q32P28,O75718,P13674 4 +Abscission 0.7165420459290468 0.8999831619115168 0.3681292114953793 1.0 1.0 3 Q96GD4 1 +Mast cell activation involved in immune response 0.5373659592565126 0.8963183463037369 0.3700827633371091 1.0 1.0 7 Q9UNH7,O95219,Q99584 3 +Meiosis i cell cycle process 0.4304320166989716 0.8959374455094561 0.3702861736128102 1.0 1.0 16 Q92791,P46100 2 +Membrane raft organization 0.4996153021368693 0.8953882989084027 0.3705795534356764 1.0 1.0 9 P41440 1 +Metal ion transport 0.3264228800978851 0.8933713595847655 0.3716583349211619 1.0 1.0 103 Q8IYU8,Q9Y666,Q8TAD4,Q6P4Q7,O14936,Q9BPX6,O75844,Q9HD20,Q9Y6M7,O43865,P17252,P08133,P05771,P21796,Q9H4I9,P30536,O15173 17 +Regulation of cellular extravasation 0.714656373673358 0.8931495282411327 0.371777102553696 1.0 1.0 3 Q08722 1 +Negative regulation of protein secretion 0.4864558989937553 0.8928057415211957 0.3719612111135932 1.0 1.0 10 Q16850,Q8N5M9,Q16836,Q8N183 4 +Response to sodium arsenite 0.7138662316476224 0.8902885069296127 0.3733109907819421 1.0 1.0 3 P07196,P09651 2 +Epoxide metabolic process 0.9161774298760532 0.8896815245306474 0.3736369172422129 1.0 1.0 2 P07099 1 +Mannosylation 0.5102833419590361 0.8881072987619989 0.3744830369457101 1.0 1.0 8 Q8NAT1 1 +Isoprenoid biosynthetic process 0.535270594093096 0.8867597660556931 0.375208253327806 1.0 1.0 7 O94788 1 +Positive regulation of g protein coupled receptor signaling pathway 0.5598594740647348 0.8854060050785223 0.375937694773143 1.0 1.0 5 P17252 1 +Regulation of membrane permeability 0.4124024133093639 0.880676885736659 0.3784927308521233 1.0 1.0 19 P45880,P52789 2 +Dna replication independent chromatin organization 0.4964029423702777 0.8792972422895828 0.3792401307542725 1.0 1.0 9 P46100 1 +Protoporphyrinogen ix metabolic process 0.558214402261777 0.878457633925591 0.3796954193138639 1.0 1.0 5 P22830,P50336 2 +Reactive oxygen species metabolic process 0.43169640245658 0.87382407639138 0.3822140666333209 1.0 1.0 42 Q13423,P00403,P42785,P52789,P30536 5 +Rna splicing via transesterification reactions 0.37757161532502 0.8716020825675396 0.3834254941746549 1.0 1.0 173 Q9Y5S9,Q7RTV0,O75940,P84103,P62312,P78332,Q96PK6,Q13123,Q08170,Q96PU8,P23246,P31942,Q13242,O75475,P52597,O43290,Q9UHI6,Q07666,P61978,P08621,Q9NW64,Q07955,O60506,O75934,Q9UKM9,P51991,P52756,O95400,P22626,Q9P013,Q14004,Q9Y4C8,P09012,Q14011,Q92945,Q86V81,O75525,P31943,Q13595,Q9BWF3,Q9H2H8,P31483,O75494,Q92879,O43390,Q92841,P49756,Q14331,Q96I25,Q8IY67,Q9Y2W1,Q16629,P98175,P62995,P07910,P98179,Q12874,Q96E39,P55081,Q9UKA9,Q96T37,P38159,P09651 63 +Epithelial cell proliferation 0.4311815560261547 0.8698878765608028 0.3843616814065926 1.0 1.0 42 P57105,O14936,P22392,Q8WTV0,Q9Y3B8,Q9UII2,O94788,P17252,Q9NQC3 9 +Aorta morphogenesis 0.7063553657769237 0.8631673129697955 0.3880454826329029 1.0 1.0 3 Q96AY3 1 +Regulation of leukocyte apoptotic process 0.4542104463063187 0.8626669591060315 0.3883206036955182 1.0 1.0 12 P00813,Q96GD4 2 +Skeletal muscle tissue regeneration 0.5542425062588768 0.8624062787260809 0.3884639866416806 1.0 1.0 6 Q7Z4V5,Q08209,P04083 3 +Mitochondrial depolarization 0.5543706575259814 0.8622498598332459 0.3885500377512074 1.0 1.0 5 P30536 1 +Amp biosynthetic process 0.4538904350649278 0.860908521851396 0.3892884277699546 1.0 1.0 12 P00813 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5535691540414657 0.8588751711711856 0.3904093890717421 1.0 1.0 5 Q9Y5S9,P38919,Q99729 3 +Pigment biosynthetic process 0.4154517958934314 0.8569467229981371 0.3914743292574831 1.0 1.0 22 P00813,P22830,P34897,O00264,Q9UII2,P30536 6 +Regulation of post translational protein modification 0.7040857973786618 0.854999864150442 0.392551222956087 1.0 1.0 3 Q32P28 1 +Muscle hypertrophy in response to stress 0.7040783034257607 0.8549729180164912 0.3925661406440019 1.0 1.0 3 P02545,P16615 2 +Negative regulation of production of mirnas involved in gene silencing by mirna 0.7040783034257594 0.8549729180164864 0.3925661406440046 1.0 1.0 3 P04637,O75844 2 +Negative regulation of cell killing 0.6091390618318304 0.8533744575412896 0.3934516814301096 1.0 1.0 4 P46108 1 +Positive regulation of epithelial cell differentiation 0.5276085450230769 0.8518909447524344 0.3942746231806715 1.0 1.0 7 Q9Y3B8 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.9041095890410902 0.8501477042500702 0.3952429723021633 1.0 1.0 2 Q96HY6 1 +Bile acid biosynthetic process 0.4904342555053038 0.8494665733679599 0.3956217225586971 1.0 1.0 9 Q9H4L5,O14975 2 +Ribonucleoprotein complex localization 0.5267467755191578 0.8479780278734794 0.3964502074443845 1.0 1.0 7 Q9BVS4,Q08J23,Q9ULX6,P12270 4 +Carnitine metabolic process 0.5506839134475201 0.8467418519170589 0.3971390255117537 1.0 1.0 5 P23786 1 +Response to estradiol 0.4304649897538806 0.8467077297090033 0.3971580492132056 1.0 1.0 15 O94788 1 +Peripheral nervous system axon regeneration 0.6074052142831512 0.8466374281621922 0.397197245233593 1.0 1.0 4 P30536 1 +Entry of bacterium into host cell 0.7007575581955134 0.8430471493685175 0.3992020749046636 1.0 1.0 3 Q9UPT5 1 +Regulation of entry of bacterium into host cell 0.7007575581955134 0.8430471493685175 0.3992020749046636 1.0 1.0 3 Q9UPT5 1 +Positive regulation of amyloid beta clearance 0.7005300714906327 0.8422312656142971 0.3996585162066599 1.0 1.0 3 Q07954 1 +Inorganic anion transmembrane transport 0.4637191615043687 0.8417680902366202 0.3999177765345236 1.0 1.0 11 Q9UHG3 1 +Oligosaccharide lipid intermediate biosynthetic process 0.6057869400179166 0.8403568800234051 0.400708318303244 1.0 1.0 4 Q2TAA5 1 +Aspartate family amino acid biosynthetic process 0.4633699069134335 0.8399166054987662 0.4009551464231817 1.0 1.0 11 Q13126 1 +Keratan sulfate metabolic process 0.6990828155774546 0.8370439934436348 0.4025678397878205 1.0 1.0 3 P15586 1 +Negative regulation of helicase activity 0.6047892844770338 0.8364886003149002 0.4028800872210591 1.0 1.0 4 P04637,P33993 2 +Regulation of rna export from nucleus 0.4754273408313902 0.8360080729374088 0.403150361477508 1.0 1.0 10 Q08J23,Q9ULX6,P12270 3 +Inner ear receptor cell development 0.5476563856731925 0.8343462299165532 0.4040859078314689 1.0 1.0 6 P54802 1 +Protein localization to endoplasmic reticulum exit site 0.6036066204491658 0.831906630970036 0.405461648709728 1.0 1.0 4 P51572 1 +Mrna 5 splice site recognition 0.6976169137790247 0.8317958241775149 0.4055242013528124 1.0 1.0 3 Q07955 1 +Peptidyl asparagine modification 0.4986811674271899 0.8317810208653992 0.4055325585541662 1.0 1.0 8 P46977,P04843,P04844,Q8TCJ2 4 +Positive regulation of hemopoiesis 0.419788192755802 0.830439656520952 0.4062902520683986 1.0 1.0 16 P00813 1 +Pyrimidine nucleoside triphosphate metabolic process 0.4483328636998136 0.8304310917173451 0.4062950927638264 1.0 1.0 12 Q9H773 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.4614387426193141 0.8296869052774228 0.4067158269571131 1.0 1.0 11 P04439,Q9UIQ6,Q03519 3 +Extracellular exosome assembly 0.6969004893963984 0.8292331093049736 0.4069725131732304 1.0 1.0 3 Q92783,Q99816 2 +Tricarboxylic acid metabolic process 0.4863733659653146 0.8292263466605888 0.4069763391418581 1.0 1.0 9 P48735 1 +Positive regulation of epidermal cell differentiation 0.5461473747867317 0.8279334666436674 0.4077081805791671 1.0 1.0 6 Q9Y3B8 1 +Positive regulation of epidermis development 0.5461473747867317 0.8279334666436674 0.4077081805791671 1.0 1.0 6 Q9Y3B8 1 +Exonucleolytic catabolism of deadenylated mrna 0.4857757311188679 0.8262517405349196 0.4086613031520323 1.0 1.0 9 Q969T7,Q13868 2 +Regulation of receptor catabolic process 0.6011482155608768 0.8223950503151336 0.4108520954937038 1.0 1.0 4 Q13614,P07355 2 +Positive regulation of cytoplasmic translation 0.4464520027261388 0.8201443005120128 0.4121338502536464 1.0 1.0 12 P67809 1 +Deoxyribonucleoside triphosphate biosynthetic process 0.6942903752038969 0.8199089435214227 0.4122680179236635 1.0 1.0 3 P23919,P55263 2 +Antigen processing and presentation of peptide antigen 0.4457981905507797 0.8165719683073859 0.4141730799052117 1.0 1.0 12 P04439,Q9UIQ6,Q03519 3 +Mitochondrial atp synthesis coupled proton transport 0.4587491725986169 0.8154628821889179 0.414807402753703 1.0 1.0 11 P00846 1 +Regulation of t cell differentiation in thymus 0.8926940639269316 0.8131202450909684 0.4161491201800125 1.0 1.0 2 P00813 1 +Negative regulation of nervous system development 0.4319699657647865 0.8121639213199892 0.416697578663034 1.0 1.0 14 Q9NQC3,P30536 2 +Mrna cis splicing via spliceosome 0.4167255059261859 0.811689560099257 0.4169697863223942 1.0 1.0 16 O75475,O43290,Q9P013,Q96I25,Q07955,Q9NW64 6 +Positive regulation of cell cycle checkpoint 0.5421384407538121 0.8109510877050693 0.4173937602771786 1.0 1.0 5 Q8N163,O14777,P12270 3 +Detection of stimulus 0.4241932996510493 0.809426035911231 0.4182701312733163 1.0 1.0 15 Q8WTV0 1 +Nucleoside triphosphate biosynthetic process 0.4226074964687315 0.806699751192407 0.4198394875075446 1.0 1.0 33 P00403,O75964,P00846,P22392 4 +Positive regulation of type i interferon production 0.3984613110161378 0.8054704335573906 0.4205482613987277 1.0 1.0 18 P10809 1 +Aspartate family amino acid metabolic process 0.4051057004717674 0.8022314671993984 0.4224190771587941 1.0 1.0 21 Q13126,Q9NRN7,Q9BQT8 3 +Lymphocyte apoptotic process 0.4229298997208578 0.8019390426524194 0.4225882202317566 1.0 1.0 15 P00813,Q96GD4 2 +Regulation of autophagy of mitochondrion 0.4149686919953556 0.8009562757093128 0.4231569591367758 1.0 1.0 16 P21796 1 +Cytoplasmic sequestering of transcription factor 0.539074756907385 0.7981766937046504 0.4247679602703971 1.0 1.0 5 O60826 1 +Histone h2a acetylation 0.4413093232653958 0.7920966858388813 0.4283043023882698 1.0 1.0 12 Q86UY6 1 +Centriole assembly 0.5375407078896824 0.7914861728919548 0.42866034175597 1.0 1.0 6 Q96PK6 1 +Response to acid chemical 0.3962809104936298 0.7912654774518303 0.4287890894270068 1.0 1.0 18 P17655,Q14103,O95831,Q99729,Q9UQB8 5 +Retina morphogenesis in camera type eye 0.5929693751945637 0.7908839050353502 0.4290117413602536 1.0 1.0 4 P54802 1 +Atp synthesis coupled proton transport 0.4408191853038338 0.7894298741877396 0.4298608010864551 1.0 1.0 12 P00846 1 +Nadh regeneration 0.5137453578857623 0.7891954585738223 0.4299977759007407 1.0 1.0 7 P52789 1 +Mrna 3 splice site recognition 0.5917956543329951 0.7863794753806491 0.431645204166839 1.0 1.0 4 Q12874 1 +Pigment granule localization 0.5359006149849285 0.7849759815016728 0.4324676510526197 1.0 1.0 5 Q13561,Q9Y4I1,Q9H267 3 +Bone development 0.4023526534548283 0.7840888993107672 0.4329879485193468 1.0 1.0 21 Q15904,O75844,P16435,Q92896,Q32P28,P08133,Q7Z3C6 7 +Tail anchored membrane protein insertion into er membrane 0.4649671541748846 0.782502042247526 0.4339195856170739 1.0 1.0 10 O43765,P46379,Q7L5D6 3 +Cerebral cortex cell migration 0.4884252123368019 0.7822930962832374 0.4340423431757902 1.0 1.0 8 Q9NQC3 1 +Nucleoside catabolic process 0.5904545184106811 0.7812382215684716 0.4346623975296242 1.0 1.0 4 P00813 1 +Protein n linked glycosylation 0.4113865970492957 0.7791248239183107 0.4359061884172996 1.0 1.0 16 P04843,Q2TAA5,P04844,Q9BT22,P46977,Q8TCJ2 6 +Response to ether 0.6816786952233254 0.7751477919485525 0.438252333921691 1.0 1.0 3 P11802 1 +Regulation of epidermis development 0.4743003995228162 0.7693660508413211 0.4416760364490009 1.0 1.0 9 Q9Y3B8 1 +Regulation of glucose transmembrane transport 0.4623739801111955 0.7693026028914645 0.4417136923952438 1.0 1.0 10 P05771,P52789 2 +Neural crest formation 0.5314747410620762 0.7666308126933025 0.4433010501224959 1.0 1.0 5 Q14978 1 +Telencephalon glial cell migration 0.508301469120934 0.7647400812525155 0.4444263338924272 1.0 1.0 7 Q9NQC3 1 +Cerebral cortex radially oriented cell migration 0.508301469120934 0.7647400812525155 0.4444263338924272 1.0 1.0 7 Q9NQC3 1 +Fat soluble vitamin metabolic process 0.5307624412711818 0.762949630783469 0.4454934356722677 1.0 1.0 6 O94788 1 +Regulation of transcription elongation from rna polymerase ii promoter 0.4233037103538372 0.7624192277576045 0.4458098340209679 1.0 1.0 14 Q8IXH7 1 +Renal tubule development 0.5296816869364283 0.7592198765218381 0.4477210378542193 1.0 1.0 5 P35222,P35610,Q12959 3 +Glycoprotein catabolic process 0.8754076973255045 0.7578154433167542 0.4485614758503213 1.0 1.0 2 O60502 1 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4091518146253258 0.7565998164273775 0.4492896513606572 1.0 1.0 27 Q13868,P67809,Q969T7,Q9HBH5,O60506,Q15024 6 +Cellular extravasation 0.4826599573791759 0.7546255835944681 0.4504736687050403 1.0 1.0 8 P46108,Q9BX67,Q08722 3 +Positive regulation of t cell proliferation 0.4593735565377929 0.7540661923576055 0.450809476479955 1.0 1.0 10 P04439,P30825,P98172,P49366 4 +3 utr mediated mrna destabilization 0.528480350839389 0.7533784423327722 0.45122253340187 1.0 1.0 6 Q9HCE1,Q92945 2 +Cellular glucose homeostasis 0.4128963476770983 0.749671496167523 0.4534525787261914 1.0 1.0 31 O00459,Q99808,Q8N183,Q15043,Q8N5M9,P62995,P85037,P17252,P52789,P17480 10 +Lymphocyte activation involved in immune response 0.4047440739303892 0.7481824715463664 0.4543501022775853 1.0 1.0 25 P10809,P00813 2 +Manganese ion transmembrane transport 0.8714938030006436 0.7454330756683343 0.4560099548548071 1.0 1.0 2 Q9HD20 1 +Manganese ion transport 0.8714938030006436 0.7454330756683343 0.4560099548548071 1.0 1.0 2 Q9HD20 1 +Tricarboxylic acid cycle 0.3958587846995832 0.7414987520909568 0.4583910881395774 1.0 1.0 21 Q13423,P48735 2 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.4251199314333536 0.7362457560137522 0.4615811509825249 1.0 1.0 13 P30040,P46379,O95881,O95831 4 +Regulation of chaperone mediated autophagy 0.6705047029123494 0.7359327855719181 0.4617716036481425 1.0 1.0 3 P08621 1 +Transition metal ion homeostasis 0.4045518230475849 0.7358738644355548 0.4618074639782421 1.0 1.0 26 Q15904,Q8TAD4,P30626,Q9Y487,Q15043,P30519,Q8N511,O60826,P35670 9 +Positive regulation of vasculature development 0.3947962509171621 0.7345597398162895 0.4626076648416415 1.0 1.0 21 P17252,P52789 2 +Glycosyl compound metabolic process 0.4072091969603184 0.7340661427157951 0.4629084272142518 1.0 1.0 28 O60725,P55263,P00813,Q9NUJ1,Q13126 5 +Striated muscle adaptation 0.5780249714479295 0.7338956999191695 0.4630123080453305 1.0 1.0 4 P02545,P16615 2 +Maintenance of protein localization in organelle 0.4245974508695671 0.7333558922632487 0.4633413937182151 1.0 1.0 13 P52789 1 +Regulation of neuron projection regeneration 0.5774067267009606 0.7315561780279963 0.4644395037588207 1.0 1.0 4 Q96G23 1 +Regulation of receptor binding 0.6689541217481849 0.7305268910387627 0.4650681818596056 1.0 1.0 3 P10586 1 +Negative regulation of proteasomal protein catabolic process 0.3941437529170917 0.7303029124323356 0.4652050483902812 1.0 1.0 21 O43765,Q96KB5,Q92530,Q96HY6,Q9UL15,P46379 6 +Positive regulation of exosomal secretion 0.5005376898991873 0.7300504918911183 0.4653593217587795 1.0 1.0 7 Q92783,Q99816,Q8WUM4,O14964 4 +Neuromuscular junction development 0.4770567255833114 0.7278557297380115 0.4667019054920103 1.0 1.0 8 P49354,Q9Y4W6 2 +Cellular transition metal ion homeostasis 0.3937462797468463 0.7277115044622743 0.4667902064222269 1.0 1.0 21 Q15904,Q8TAD4,P30626,Q9Y487,Q15043,Q8N511,O60826,P35670 8 +Bone remodeling 0.4651914529796699 0.7245712684536793 0.4687150905174058 1.0 1.0 9 Q92791 1 +Midbrain development 0.3857834204238993 0.7233291158118567 0.4694777089603108 1.0 1.0 18 Q16352,P35222,P62258,P00367,P63167,P80723,P60953,P27348,O14949,P24539,Q04917 11 +Positive regulation of adaptive immune response 0.3940781357248673 0.7223074790664779 0.4701054556681003 1.0 1.0 17 P00813 1 +Regulation of dna duplex unwinding 0.5749511885429779 0.7222792866443339 0.4701227851291749 1.0 1.0 4 Q04837,P33993 2 +Cellular response to lipoprotein particle stimulus 0.6652528548123783 0.717660184520013 0.4729668387048802 1.0 1.0 3 Q5JRA6,O15118 2 +Sterol biosynthetic process 0.3943647361456424 0.7175455954789464 0.4730375131367728 1.0 1.0 22 Q15392,Q15126,P37268,P16435,Q16850,O75477,Q14534 7 +Second messenger mediated signaling 0.4000111322937895 0.7166955148150951 0.4735619939945592 1.0 1.0 25 P00813,P17252,O75844 3 +In utero embryonic development 0.2996988933425837 0.7154490237475353 0.4743316291706732 1.0 1.0 87 P00813,P23786,Q15293,P67809,Q96EK5,Q96AY3,Q9NQC3,O43772,Q16706 9 +Protein localization to condensed chromosome 0.4625110498729785 0.7114601140229863 0.4767991589292921 1.0 1.0 9 Q96DY7 1 +Mitotic g2 m transition checkpoint 0.4261241097185527 0.7100649229890953 0.4776638770269059 1.0 1.0 12 Q96JB5 1 +Regulation of t cell differentiation 0.4200024210139864 0.7080146316990402 0.4789361712340469 1.0 1.0 13 O96005,P00813 2 +Regulation of leukocyte proliferation 0.3984833616122717 0.7065713423636852 0.479832903165696 1.0 1.0 25 P04439,P00813,P98172,Q12959,P30825,P49366,P04083 7 +Inorganic ion import across plasma membrane 0.4724071510408201 0.7057411319443898 0.4803491368312522 1.0 1.0 8 Q9Y666,Q15043,Q12959 3 +Ventricular septum morphogenesis 0.6613928920325675 0.7042994218874836 0.4812463262741782 1.0 1.0 3 O96028 1 +Regulation of erad pathway 0.5159946484023152 0.7030919860625287 0.4819984260771583 1.0 1.0 5 P46379,P51572 2 +Regulation of receptor localization to synapse 0.6606851549755283 0.7018562326185321 0.4827688260437588 1.0 1.0 3 Q14118,O15400 2 +Regulation of chondrocyte differentiation 0.5688972102242877 0.6995151087549495 0.4842301742290322 1.0 1.0 4 Q92896 1 +Regulation of cartilage development 0.5688972102242877 0.6995151087549495 0.4842301742290322 1.0 1.0 4 Q92896 1 +Negative regulation of leukocyte mediated immunity 0.5149053628271637 0.6968680153206908 0.4858853959824913 1.0 1.0 6 P46108 1 +Purine nucleoside monophosphate biosynthetic process 0.411655718100469 0.6962588448319273 0.4862667417579063 1.0 1.0 14 P00813 1 +Synaptonemal complex organization 0.5141385805596628 0.6955456572530302 0.4867134086615148 1.0 1.0 5 Q92791,P46379 2 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3812690534973674 0.694377073623607 0.4874457675579808 1.0 1.0 18 O43765,Q96KB5,Q96HY6,Q9UL15,P46379 5 +Regulation of hormone levels 0.3532361705446126 0.6942749596651209 0.4875097912862038 1.0 1.0 68 Q8TAD4,O95219,O75844,Q8N183,Q15043,Q16836,P16435,Q9HB40,Q969M3,O94788,Q6NUM9,P42892,Q9Y394,P53985,P30536 15 +Bile acid and bile salt transport 0.8548597521200156 0.6934402350941564 0.4880333196787729 1.0 1.0 2 O15439 1 +Long chain fatty acyl coa biosynthetic process 0.4920351260065352 0.6923441339180264 0.4887212404057577 1.0 1.0 7 Q9UKU0 1 +Hematopoietic stem cell homeostasis 0.5668387654358946 0.6918111754713594 0.4890559175642024 1.0 1.0 4 Q14157 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.854207436399206 0.6914232643653173 0.4892995882486717 1.0 1.0 2 Q9UIQ6 1 +B cell activation 0.4073106186212927 0.6910001611783629 0.4895654397580822 1.0 1.0 35 Q9UQ84,P10809,P00813 3 +Divalent inorganic cation homeostasis 0.3908439058523373 0.6881870597577965 0.4913349917165246 1.0 1.0 55 Q96TC7,Q8IYU8,Q8TAD4,Q6P4Q7,Q9BPX6,Q15043,Q96AQ8,Q9Y4W6,Q16891,Q9HD20,P17252,P51572,P08133,P05771,P35670,Q9H4I9 16 +Autophagy of mitochondrion 0.4036436189814281 0.6860442367669316 0.4926852132848145 1.0 1.0 31 Q96CV9,Q9UII2,P52789,P21796,P30536 5 +Regulation of epithelial cell differentiation 0.4018181121099488 0.6782617601374686 0.4976057399068589 1.0 1.0 15 P22392,Q9Y3B8 2 +Gmp metabolic process 0.3866158283808945 0.6761326315074698 0.4989564403790856 1.0 1.0 17 P55263,P00813 2 +Forebrain cell migration 0.4544459792624502 0.6722262192003956 0.5014396917445507 1.0 1.0 9 Q9NQC3 1 +Ion homeostasis 0.3138621816773782 0.6687464355651687 0.5036572407405253 1.0 1.0 108 Q15904,Q8IYU8,Q96TC7,Q8TAD4,Q6P4Q7,Q9Y666,Q9BPX6,Q9HD20,P30519,Q93050,P17252,P08133,Q8N511,P05771,P51572,Q9H4I9,P30536 17 +Dicarboxylic acid transport 0.3851577557374566 0.6671666072287868 0.5046657182990137 1.0 1.0 17 Q9UBX3,Q9BQT8,P41440 3 +Embryonic organ development 0.4016504650731939 0.6665047884084437 0.5050885040477135 1.0 1.0 46 Q9H6E4,P00813,P54802,P62995,O94788,P42892 6 +Negative regulation of blood circulation 0.6499184339314757 0.6649509177900044 0.5060818868340413 1.0 1.0 3 P16615,P30626 2 +Positive regulation of cell cycle g1 s phase transition 0.3923221970003634 0.6643860275186002 0.5064432733449968 1.0 1.0 16 Q96DY7 1 +Regulation of antigen receptor mediated signaling pathway 0.4635332423892601 0.6638131848104153 0.5068098859320935 1.0 1.0 8 P00813 1 +Regulation of blood circulation 0.3952430694879876 0.66345219200341 0.5070409887024021 1.0 1.0 27 P42892,P00813,P17252 3 +Prostanoid metabolic process 0.4171258778407534 0.6621253990501158 0.507890859307411 1.0 1.0 12 Q15067,Q8N8N7 2 +Skeletal muscle acetylcholine gated channel clustering 0.5058223770116752 0.6619449215439128 0.5080065210038966 1.0 1.0 5 P49354 1 +Hepaticobiliary system development 0.4025599257744445 0.6616954894946959 0.5081663959917546 1.0 1.0 34 P00813,Q96JB5,O94788,Q16706 4 +Sarcoplasmic reticulum calcium ion transport 0.4517404287896664 0.6591430439938102 0.5098039171506574 1.0 1.0 9 P30626,P17252,O75844 3 +Vascular endothelial growth factor receptor signaling pathway 0.5052915736657442 0.6573411891622012 0.5109615575848065 1.0 1.0 6 P05771 1 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4840402451876358 0.6571959417550297 0.5110549346918005 1.0 1.0 7 Q9UL15 1 +Proton transporting two sector atpase complex assembly 0.5039164985619925 0.6542954684216594 0.5129214648460745 1.0 1.0 5 Q8N511 1 +Establishment of rna localization 0.3010043827541198 0.6524737005537123 0.5140956333561875 1.0 1.0 94 P84103,Q96PU8,Q08J23,P41208,Q9BTX1,P61970,Q8NFH5,P67809,Q8TD16,Q86U42,Q07955,P51991,P22626,Q92945,P12270,Q53F19,Q8N1F7,Q12769,Q8NFH4,P41440,Q16629,Q9Y6M1,P09651 23 +Regulation of neuron differentiation 0.376979216847866 0.6505330455126255 0.5153479633366633 1.0 1.0 19 Q8WUJ1 1 +Phospholipid transport 0.3966028455305751 0.6482121199607402 0.5168477639770237 1.0 1.0 15 Q7Z3C6,P08183,Q8WTV0,Q14108 4 +Positive regulation of nucleobase containing compound transport 0.5541547230853257 0.6447778217089914 0.5190711763016422 1.0 1.0 4 Q07666 1 +Positive regulation of rna export from nucleus 0.5541547230853257 0.6447778217089914 0.5190711763016422 1.0 1.0 4 Q07666 1 +Prenylation 0.5014129742206607 0.6442777260727729 0.5193953566423848 1.0 1.0 5 P53609 1 +Mrna catabolic process 0.3028171287655934 0.6429263887778061 0.5202718654637442 1.0 1.0 97 P62312,Q13868,Q15717,Q969T7,Q15024,Q13151,P67809,Q99729,P17252,O60506,Q92804,Q14011,Q92945,Q9HBH5,Q9HCE1,P35637,Q9Y2W1,P98175,P07910,P08670 20 +Signal peptide processing 0.5007374322655531 0.6415806138278326 0.5211455235733193 1.0 1.0 5 Q15005,Q8TCT9,P67812 3 +Response to molecule of bacterial origin 0.4007163401024107 0.6391120187925078 0.5227500617460774 1.0 1.0 37 O43823,P11802,Q13151,Q86U42,Q8WTV0,P17252,P08670,P30536 8 +Positive regulation of cellular extravasation 0.8369210697977796 0.6386288858974065 0.5230643852350028 1.0 1.0 2 Q08722 1 +Icosanoid metabolic process 0.3723634453037965 0.6378139437199533 0.5235948017135863 1.0 1.0 18 P07099,Q15067,Q8N8N7 3 +Glucose catabolic process 0.4359284627679484 0.6366056205028175 0.5243817632429404 1.0 1.0 10 P52789 1 +Zymogen activation 0.5000900996187541 0.6361485484756807 0.5246796048223512 1.0 1.0 6 Q15392 1 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.423753845814821 0.6336301413590931 0.5263222253586197 1.0 1.0 11 P14174,P61978,Q9BVC6,Q96RU2,P46379 5 +Carbohydrate transmembrane transport 0.4062575870351137 0.633105654468977 0.5266646500060346 1.0 1.0 13 P05771,Q16625,P52789 3 +Mitotic spindle midzone assembly 0.49812570905163 0.6311779591772224 0.5279241717270786 1.0 1.0 5 Q96GD4 1 +Negative regulation of cysteine type endopeptidase activity 0.3763524491490254 0.6307778631891771 0.5281857795621134 1.0 1.0 20 Q9Y3B8 1 +Cell recognition 0.3736232668957621 0.6292718835166488 0.5291710752929433 1.0 1.0 19 P45880,Q8WTV0,Q14157,Q9NQC3 4 +Mitotic nuclear membrane organization 0.4974490777478962 0.6284893929097444 0.5296833930858484 1.0 1.0 5 Q86XL3 1 +Endoplasmic reticulum membrane organization 0.4773243958353057 0.6279277457282818 0.5300512740790668 1.0 1.0 7 Q8NHH9,Q9NQC3,Q9P2W9 3 +Unsaturated fatty acid metabolic process 0.3779959167247084 0.6261706074513615 0.5312030439080131 1.0 1.0 21 P07099,Q15067,O15121,Q8N8N7 4 +Neural nucleus development 0.3857734969083685 0.6256605908948577 0.5315375873227337 1.0 1.0 16 Q16352,P62258,Q14160,P00367,P63167,P80723,P60953,P27348,P24539,Q04917 10 +Regulation of protein maturation 0.4447705232016283 0.6256385177555851 0.5315520685250543 1.0 1.0 9 P17252 1 +Pyrimidine nucleoside metabolic process 0.6381729200652411 0.6252937868930242 0.5317782570187513 1.0 1.0 3 P23919,P84090 2 +Cellular response to arsenic containing substance 0.4443255182576845 0.6235096660449141 0.5329496522928516 1.0 1.0 9 O00571,Q9UER7,P09601,P09651,Q96QD8 5 +Regulation of nitric oxide metabolic process 0.4216900709338068 0.6231461253270205 0.5331885011889601 1.0 1.0 11 P30536,Q92945 2 +Somatic diversification of immunoglobulins involved in immune response 0.3918636047241641 0.6211141008923342 0.5345245520682198 1.0 1.0 15 Q9UQ84,P10809,Q96FZ2 3 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3918636047241641 0.6211141008923342 0.5345245520682198 1.0 1.0 15 Q9UQ84,P10809,Q96FZ2 3 +Nuclear envelope organization 0.392848909118237 0.6204302730238199 0.5349745467718852 1.0 1.0 30 Q5JTV8,Q9HD42,Q9BTV4,Q86XL3,O75844,P50402,Q9H6H4,P02545,Q8N1F7,P17252,P05771,P53350,P20700 13 +Regulation of animal organ morphogenesis 0.4961669305002594 0.6202611148157671 0.5350858912359542 1.0 1.0 6 P35222,Q8TAA9,P60953,Q99623 4 +Aromatic amino acid transport 0.8307240704500911 0.62002752546043 0.5352396652124267 1.0 1.0 2 P30825 1 +Regulation of t cell activation 0.3976092678255147 0.6172009596387048 0.5371021828396991 1.0 1.0 37 Q9Y255,P10809,P00813,O96005,P98172,P30825,Q08722 7 +Carbohydrate transport 0.3763144970038353 0.6132289844686855 0.5397249423266253 1.0 1.0 17 P05771,Q16625,P52789 3 +Calcium ion transport 0.379746297001951 0.6111178081316907 0.5411215911862266 1.0 1.0 56 Q8IYU8,Q9BPX6,P17252,P08133,P05771,P21796,Q9H4I9,P30536 8 +Negative regulation of endothelial cell proliferation 0.4934433459779294 0.6092829954751217 0.5423368762575964 1.0 1.0 6 P57105 1 +Negative regulation of defense response 0.3910663363625686 0.6085297432889154 0.5428361853010033 1.0 1.0 30 P28070,P00813,P46108,O43657,Q96KB5 5 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.8268101761252441 0.6083731274946786 0.5429400301249825 1.0 1.0 2 Q07954 1 +Iron ion transport 0.4516193321463621 0.6081827002596248 0.5430663071101889 1.0 1.0 8 Q15043,Q9H9B4,Q07960,O15173 4 +Regulation of cell division 0.3833227710183985 0.607329611679998 0.5436321906192199 1.0 1.0 25 Q9Y3B8,Q86Y91,P67809,Q96GD4 4 +Positive regulation of glycoprotein metabolic process 0.4513583553545601 0.6069735447813395 0.5438684690155657 1.0 1.0 8 Q96IZ0,Q08379,P35610,Q92542 4 +Glycolytic process through fructose 6 phosphate 0.4407215743935712 0.6063169788645824 0.5443042860433374 1.0 1.0 9 P52789 1 +Neurofilament cytoskeleton organization 0.825505544683616 0.604504870723938 0.5455080319129513 1.0 1.0 2 Q16352 1 +Cellular ion homeostasis 0.2905398023373625 0.6040202437630748 0.5458301832623254 1.0 1.0 86 Q15904,Q15043,Q93050,Q9H4I9,Q8TAD4,Q96AQ8,P17252,P51572,P05771,P35670,Q96TC7,Q9Y487,P06576,Q16891,Q9HD20,Q9Y6M7,P08133,Q8N511,Q8IYU8,Q9BPX6,Q9Y4W6,O60826 22 +Regulation of atp dependent activity 0.3872123376676203 0.600602207928148 0.5481049670274545 1.0 1.0 28 Q5JTV8,Q96GC9,P35080,P08621,Q15070,Q9UII2,P20585,P04637 8 +Positive regulation of calcium ion transport 0.3943683221228957 0.5999549075261277 0.5485362877500732 1.0 1.0 14 P30626,O14936,P30536 3 +Amp metabolic process 0.3879680648265391 0.5990015936254232 0.5491718218627681 1.0 1.0 15 P00813 1 +Homologous chromosome pairing at meiosis 0.4490209722696269 0.5961633779247488 0.5510660881844631 1.0 1.0 8 Q92791 1 +Demethylation 0.3803103823483994 0.5936802740222497 0.5527259790276084 1.0 1.0 16 Q8NB78,Q16850 2 +Amyloid beta clearance 0.4480012661810896 0.5914584516335812 0.5542132859410787 1.0 1.0 8 Q07954,Q13464,Q16850 3 +Homologous chromosome segregation 0.4374360924415056 0.590721001278615 0.5547073740556698 1.0 1.0 9 P46379,Q92791,Q9BTX1 3 +Positive regulation of double strand break repair via homologous recombination 0.3724928303414065 0.5901757043163429 0.5550728588009703 1.0 1.0 17 Q7Z4V5,P35637 2 +Negative regulation of sister chromatid cohesion 0.819960861056739 0.5881591798556174 0.5564254536593634 1.0 1.0 2 P46100 1 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.81963470319634 0.5872025001474577 0.5570677134561679 1.0 1.0 2 P51572 1 +Regulation of potassium ion import 0.5382317534912507 0.5869227598554099 0.5572555832287542 1.0 1.0 4 Q12959 1 +Nucleoside phosphate catabolic process 0.3668404622906696 0.5866866454779069 0.5574141784383377 1.0 1.0 19 P00813 1 +Regulation of dna helicase activity 0.6261011419249548 0.5852601699444827 0.5583727921528563 1.0 1.0 3 Q04837,P33993 2 +Leukotriene biosynthetic process 0.6260374323609135 0.5850509729794944 0.5585134431112762 1.0 1.0 3 P09960 1 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.817677756033915 0.5814738791753022 0.5609211178690161 1.0 1.0 2 Q8N183 1 +Dorsal ventral pattern formation 0.4854663855671141 0.5813461736777491 0.5610071668473917 1.0 1.0 5 P17252,Q7Z4L5 2 +Negative regulation of cell projection organization 0.3856219184601273 0.5809369343384225 0.5612829585986392 1.0 1.0 29 Q9NQX7,Q9NR77,Q9UL15,Q9NQC3,P08670 5 +Cellular response to carbohydrate stimulus 0.3790838617780523 0.5800388763239042 0.5618884014592829 1.0 1.0 25 Q99808,Q8N183,P17480,Q15043,Q8N5M9,P62995,P17252,P05771 8 +Regulation of t cell proliferation 0.362590135673666 0.5767225164412595 0.5641269193432916 1.0 1.0 18 P04439,Q96EY1,P02786,P35222,P98172,Q12959,Q96IZ0,P30825,P49366,P04083 10 +Import across plasma membrane 0.3676035188008886 0.5756916990028629 0.5648235871538669 1.0 1.0 20 Q9Y666,P41440,Q15043,P30825,Q8TDW0,P33121 6 +Positive regulation of nf kappab transcription factor activity 0.3743877672719681 0.575272115279538 0.5651072771317027 1.0 1.0 23 Q96HY6,P41440 2 +I kappab phosphorylation 0.8147423352902672 0.5729181705009312 0.5667001009478818 1.0 1.0 2 Q96HY6 1 +Activation of phospholipase d activity 0.6216433911546704 0.5706778510771897 0.5682180353726758 1.0 1.0 3 Q14344 1 +Interleukin 10 production 0.5336838048517119 0.570669149168866 0.5682239351633696 1.0 1.0 4 P10809 1 +Xenobiotic export 0.8137638617090527 0.5700763127777482 0.5686259401817118 1.0 1.0 2 P08183 1 +Chaperone mediated protein complex assembly 0.4222660827003018 0.5697941002673106 0.5688173574977884 1.0 1.0 10 P10809,O15212 2 +Histone h4 acetylation 0.3753374044924277 0.5683520668826327 0.5697959310680347 1.0 1.0 24 Q86UY6,Q9NPF5,O75844 3 +N acetylglucosamine metabolic process 0.5326107927998077 0.5668531780143066 0.5708139375592656 1.0 1.0 4 O60502 1 +Maintenance of dna repeat elements 0.5325948782102069 0.566796635641329 0.5708523566208186 1.0 1.0 4 O75844 1 +Regulation of platelet derived growth factor receptor beta signaling pathway 0.8121330724070431 0.5653511699335707 0.5718349305571886 1.0 1.0 2 Q07954 1 +Response to interleukin 7 0.4319730227715624 0.56496187310239 0.5720996974557844 1.0 1.0 9 P67809 1 +Odontogenesis 0.4619740622365351 0.5620403702660784 0.5740885140815393 1.0 1.0 7 P35221,P07942,P35222,P35613,Q6P4Q7 5 +Steroid esterification 0.6185970636215151 0.5607782850495882 0.5749486917430704 1.0 1.0 3 P35610,P24752 2 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.8095238095238042 0.5578205947058233 0.5769668980289453 1.0 1.0 2 Q15043 1 +Microtubule organizing center organization 0.3894062954818557 0.557774556506105 0.5769983389750706 1.0 1.0 38 Q15004,Q9UBK9,Q08379,Q96PK6,Q9H6D7,Q7Z4H7,O14974,P53985,P41208 9 +Negative regulation of cell cycle g2 m phase transition 0.3621035685414968 0.5572823939652789 0.5773345028182146 1.0 1.0 19 Q68E01,Q96JB5 2 +Negative regulation of epithelial cell proliferation 0.3862225880257973 0.5555455695424394 0.5785215498087526 1.0 1.0 14 Q9Y3B8,Q9UII2,P57105 3 +Mitotic chromosome condensation 0.4080600710994398 0.5547799923548432 0.5790451538837791 1.0 1.0 11 O43823,Q9HD42,P53350 3 +Folic acid containing compound catabolic process 0.6158426786349243 0.5518745766015352 0.5810342878635366 1.0 1.0 3 Q9NRN7 1 +Protein import into peroxisome membrane 0.615519202316825 0.5508319048904864 0.5817489108191047 1.0 1.0 3 P56589 1 +Non canonical wnt signaling pathway 0.4775768903442312 0.550830054668511 0.5817501792833104 1.0 1.0 5 Q8TAA9,Q63HN8,P60953 3 +Aerobic respiration 0.2839003835277416 0.5502788075222271 0.5821281575875084 1.0 1.0 83 Q13423,P48735,P00403,O75964,O43676,P00846,P22695,Q9UDW1,P03915 9 +Nuclear ncrna surveillance 0.4772526257779443 0.5495853618375671 0.5826038012190389 1.0 1.0 5 Q13868 1 +Mrna methylation 0.4781520363815418 0.5485004658644487 0.5833483094714322 1.0 1.0 6 Q96FX7 1 +Embryonic pattern specification 0.4772854184753937 0.5451022400404378 0.5856832021528626 1.0 1.0 6 P80723,Q9UK61,P98172 3 +Substantia nigra development 0.378294020105144 0.5447861262198234 0.5859006217042908 1.0 1.0 15 Q16352,P62258,P00367,P63167,P80723,P60953,P27348,P24539,Q04917 9 +Negative regulation of macroautophagy 0.4164430520185519 0.5417726934345382 0.587975104798141 1.0 1.0 10 Q9P275,O15118,P04637,P09601 4 +Endothelial cell migration 0.3848825474261175 0.5408150308201976 0.5886350815675887 1.0 1.0 34 P42785,P17252,Q8WTV0 3 +Carboxylic acid transport 0.3853459807873005 0.5391544625757764 0.5897802785535347 1.0 1.0 35 P07602,P41440,O15439,Q8TDW0,Q9BQT8,P53985,Q9UBX3 7 +Positive regulation of cell division 0.4153660039188646 0.5366225108169151 0.5915283915125018 1.0 1.0 10 P67809,Q96GD4 2 +Immune response regulating signaling pathway 0.3745912841016666 0.5357320380079188 0.5921437580934086 1.0 1.0 54 Q9NPR9,P10809,P00813,P41440,O43657,P05771 6 +Cellular response to oxygen levels 0.383873225152355 0.5340406104010968 0.5933134375966769 1.0 1.0 34 Q15904,O95831,P02545,Q8N511,P55786 5 +Regulation of calcium ion transport 0.378204545963575 0.5325816920971282 0.5943231781957905 1.0 1.0 29 P21796,P30536 2 +Blastocyst development 0.3817969416390483 0.5322539774021177 0.5945501027646181 1.0 1.0 32 P00813 1 +Histamine production involved in inflammatory response 0.471707978563074 0.5284244008653646 0.5972048053096641 1.0 1.0 5 O95219 1 +Histamine secretion 0.471707978563074 0.5284244008653646 0.5972048053096641 1.0 1.0 5 O95219 1 +Histamine transport 0.471707978563074 0.5284244008653646 0.5972048053096641 1.0 1.0 5 O95219 1 +Positive regulation of ubiquitin protein ligase activity 0.6083905900872273 0.5280174346598899 0.597487235137351 1.0 1.0 3 P53350 1 +Amyloid beta formation 0.4022307939293912 0.5260568746548184 0.5988486909800801 1.0 1.0 11 O95197 1 +Positive regulation of translation 0.3603680669581134 0.5224473762242955 0.6013588771758265 1.0 1.0 60 Q567V2,Q14011,P67809,A9UHW6,P98179,O15031,O60506,Q9Y2R0,P08670,Q6P087 10 +Cellular response to lipid 0.2936187629633421 0.5216817426252756 0.6018919385960815 1.0 1.0 97 O43823,O15173,Q9P253,O95831,Q8WTV0,P17252,O94788,Q96HY6,P08670,P30536 10 +Myeloid progenitor cell differentiation 0.7968036529680331 0.5216494361186499 0.6019144362224118 1.0 1.0 2 Q9BX67 1 +Odontogenesis of dentin containing tooth 0.4710663602412618 0.5208745905546176 0.6024541372443442 1.0 1.0 6 P35221,Q6P4Q7 2 +Rrna catabolic process 0.3849669779723588 0.5203894077106964 0.6027921912350735 1.0 1.0 13 Q9BQ61,Q13868 2 +Rrna pseudouridine synthesis 0.5179917426217715 0.515623958772357 0.6061170734239605 1.0 1.0 4 Q6P087 1 +Establishment of lymphocyte polarity 0.604442780096988 0.5155212357806757 0.6061888341302182 1.0 1.0 3 Q14160 1 +Xenobiotic metabolic process 0.3886488808218305 0.5148548075247327 0.6066544829646023 1.0 1.0 12 P07099 1 +Nadh dehydrogenase complex assembly 0.373911306354764 0.5144451531505869 0.6069407972637189 1.0 1.0 28 Q86Y39,Q8N183,O96000,O43676,Q9P0J0,Q9Y6M9,P03915,Q9H061,Q96CU9 9 +Regulation of p38mapk cascade 0.6039527045225496 0.5139770569948517 0.607268031373285 1.0 1.0 3 Q12959 1 +P38mapk cascade 0.6039527045225496 0.5139770569948517 0.607268031373285 1.0 1.0 3 Q12959 1 +Mesenchymal cell differentiation 0.3788825013978849 0.5130808851721939 0.6078947419172027 1.0 1.0 32 P98172,Q99729,Q14978,O94788,P08133,Q9NQC3,Q13428 7 +Negative regulation of dna binding transcription factor activity 0.3676123321391338 0.5073947830019871 0.6118778454958815 1.0 1.0 25 P30626,Q00577,Q96RT1,O75381,O60826,P09525,Q96JB5 7 +Nuclear export 0.2831571641697433 0.5065352582218641 0.61248094458715 1.0 1.0 86 P84103,P82979,Q9Y3B8,Q08J23,P61970,Q86U42,Q9NW64,P17252,P22626,Q9ULX6,P50402,Q96GA3,P12270,O43865,Q86V81,Q53F19,Q8N1F7,Q14012,Q12769,Q9BVS4,P09651 21 +Protein peptidyl prolyl isomerization 0.3672775168732631 0.5053036823961901 0.6133455568302726 1.0 1.0 25 Q96AY3,Q9NWM8 2 +Ornithine transport 0.7909328114807466 0.5052700457910556 0.6133691785390412 1.0 1.0 2 P30825 1 +Cell communication by electrical coupling involved in cardiac conduction 0.4665970334457265 0.5036427136878411 0.6145124711709407 1.0 1.0 6 P17252 1 +Regulation of cell aging 0.3809990793133519 0.4999262625128274 0.6171269992340986 1.0 1.0 13 P14174,O75844,P67809,Q96IZ0,P02545,Q9NRM2 6 +Positive regulation of antigen receptor mediated signaling pathway 0.5131863870177222 0.4991135672513532 0.6176993801812138 1.0 1.0 4 P00813 1 +Angiotensin activated signaling pathway 0.5122457799075957 0.4959019799650099 0.6199635691603742 1.0 1.0 4 Q6RW13,O43865 2 +Receptor clustering 0.3748570375672983 0.4948394167930429 0.6207134781878316 1.0 1.0 14 Q14168,P57105,O43805,Q14696,P49354 5 +Ketone body metabolic process 0.5974394572629739 0.493606966652905 0.6215837797447654 1.0 1.0 3 P35610 1 +Ribonucleoside monophosphate biosynthetic process 0.3515761831661411 0.4930591359613143 0.621970803537238 1.0 1.0 19 P00813 1 +Negative regulation of cellular amide metabolic process 0.2794408107440875 0.4916836856158808 0.6229429731276608 1.0 1.0 83 Q9BWF3,O95197,Q14011,P67809,Q92945,Q969T7,Q13868,Q00577,P34897,P12270,O60506,Q9Y6M1,Q15024,Q9HCE1,Q9NQC3,Q10713 16 +Regulation of adaptive immune response 0.35869482958017 0.4912846471886615 0.6232251370030297 1.0 1.0 22 P00813 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.7853881278538682 0.4899916010737739 0.6241398421350062 1.0 1.0 2 Q9NQX7 1 +Cellular response to unfolded protein 0.3694343849134306 0.4860350149205721 0.6269423403161967 1.0 1.0 28 Q96HY6,P10809,P48723,Q96JB5 4 +Embryo implantation 0.3934444875511033 0.4834287502019471 0.6287913385289969 1.0 1.0 11 Q8IZL8,P84243 2 +U4 snrna 3 end processing 0.4607634247504257 0.4813894675027572 0.6302397209590278 1.0 1.0 6 Q15024,Q9NQT4,Q13868 3 +Organelle disassembly 0.3755429082904528 0.4812301727587267 0.6303529185967394 1.0 1.0 48 Q08379,Q96CV9,Q9UII2,P52789,Q9Y6I9,P21796,Q96HY6,P30536 8 +Somatic diversification of immunoglobulins 0.3493939704520738 0.4799602175773612 0.6312556811931478 1.0 1.0 19 P10809,Q9UQ84,P20585,Q96FZ2 4 +Pore complex assembly 0.3770520104105692 0.4797647961301873 0.6313946477251715 1.0 1.0 13 Q9NQC3,Q9BTX1,P12270 3 +Cardiac septum morphogenesis 0.4584900806683675 0.4789714273282015 0.6319589555657752 1.0 1.0 5 O96028,Q96T37 2 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.5070648917295176 0.4783345382243238 0.6324121176414945 1.0 1.0 4 O14777,P12270 2 +Determination of adult lifespan 0.4417703554995412 0.4778854672433627 0.6327317255681986 1.0 1.0 7 P46100 1 +Regulation of phospholipase activity 0.4129490938859895 0.4771897095578452 0.6332270381315166 1.0 1.0 9 Q14344,Q99623,Q07954,P18085,P50897,P04083 6 +Centromere complex assembly 0.4027436602315438 0.4770979423272237 0.6332923798561616 1.0 1.0 10 P49454,P84243 2 +Carbohydrate homeostasis 0.3775275013849596 0.4768266535553644 0.6334855644082655 1.0 1.0 44 O00459,P30626,Q99808,Q8N183,Q15043,P42785,Q8N5M9,P62995,P85037,P17252,P52789,P49366,P17480,P53985 14 +Glucosamine containing compound metabolic process 0.457813388496292 0.476479721745422 0.6337326507310013 1.0 1.0 5 O60502 1 +Aminoglycan metabolic process 0.3710527665134831 0.4748863737076145 0.6348679642841981 1.0 1.0 14 P06865,Q7LGA3,P54802,P15586,P16278,O94923 6 +Regulation of metallopeptidase activity 0.5060386568164006 0.4748797635736002 0.6348726760163979 1.0 1.0 4 Q96HY6 1 +Cellular response to corticosteroid stimulus 0.3805236016811807 0.4743914741661128 0.6352207717131046 1.0 1.0 12 O95831 1 +Cardiac cell development 0.3915072977491892 0.4741459575677691 0.6353958280405576 1.0 1.0 11 P02545,O75844 2 +Pyrimidine nucleotide metabolic process 0.3648738690949759 0.4714776625730979 0.6372996674762188 1.0 1.0 15 Q9H773 1 +Negative regulation of response to wounding 0.4396460027142397 0.4692327282445905 0.6389032941692354 1.0 1.0 7 Q96G23,P46108 2 +Hepatocyte growth factor receptor signaling pathway 0.4557623245184456 0.4689523550177121 0.6391036923732578 1.0 1.0 5 P18031,P16949,Q9NWH9,P63000 4 +Epigenetic maintenance of chromatin in transcription competent conformation 0.455281171404428 0.4671920360918992 0.6403624909516679 1.0 1.0 5 O14497,Q969T9,O75151 3 +Membrane protein ectodomain proteolysis 0.4000272822824414 0.4645033619398242 0.6422871514044455 1.0 1.0 10 P38159 1 +Mrna modification 0.3890764304952324 0.4625601049956002 0.6436797104472318 1.0 1.0 11 Q96FX7,Q99729 2 +Ion transport 0.36847210698757 0.4587791963753609 0.6463927355083741 1.0 1.0 209 O95219,O14936,Q70HW3,P00403,Q15043,Q8TB61,Q9UDW1,Q8TDW0,Q9UHG3,P30825,P21796,Q6N075,O43772,Q9H4I9,O15173,Q8TAD4,O75844,O75964,P00846,P08183,P17252,P05771,Q9UBX3,P30536,Q6P4Q7,Q13423,Q9Y666,O15439,Q9HD20,Q9Y6M7,P45880,O43865,P08133,P53985,P03915,Q8IYU8,P07602,Q99808,P41440,Q9BPX6,Q9BQT8 41 +Response to retinoic acid 0.3725851050809056 0.4571951116863965 0.6475308116085419 1.0 1.0 13 P11717,Q9P0J0,O94788 3 +Regulation of translation in response to stress 0.3984105074146389 0.4570459719177936 0.647638002680621 1.0 1.0 10 Q9BWF3 1 +Carbohydrate derivative catabolic process 0.3736612159710615 0.4566733940722852 0.6479058170944776 1.0 1.0 36 Q9H773,P00813,P35610,Q9NUJ1,P54802,P15586,Q9BTY2,Q13126,Q9BW91,O60502,P16278,Q8TCJ2 12 +Intermembrane lipid transfer 0.4522006258285367 0.455972140456934 0.6484100120498915 1.0 1.0 5 P30536 1 +Peptidyl glutamic acid modification 0.4519090216183691 0.4549146359986038 0.649170652972654 1.0 1.0 5 Q8N0U8 1 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.7723418134376956 0.4548065339045161 0.6492484291878617 1.0 1.0 2 Q8TB61 1 +Establishment of protein localization to membrane 0.2816917218450345 0.4543265351613728 0.6495938200667677 1.0 1.0 89 Q15904,Q96CV9,Q15070,Q9P0J0,P62072,Q4J6C6,Q9NS69,O43765,Q7L5D6,P40855,P56589,Q9Y276,O14737,P49069,Q9Y584,Q9HD20,P46379,O60725,Q15629,Q9H173,P43307,O15118 22 +Response to bacterium 0.3590486260318714 0.4536882195271851 0.6500532471169085 1.0 1.0 57 O43823,P04439,Q9UQB8,P11802,Q13151,Q96CV9,Q9BTY2,Q86U42,Q8WTV0,P17252,P81605,P08670,P30536 13 +Muscle cell migration 0.3759901897437945 0.4521765408396337 0.6511418068188655 1.0 1.0 12 O15511,P46108,Q07954,Q13464,P31949,P04083 6 +Nuclear membrane organization 0.3497930454712967 0.4518615552158514 0.6513687217133852 1.0 1.0 21 Q5JTV8,Q9HD42,Q9BTV4,Q86XL3,P50402,Q9H6H4,P17252,P05771,P53350 9 +Protein localization to chromosome centromeric region 0.3867290105160266 0.4514399645330471 0.6516724851818769 1.0 1.0 11 Q96DY7 1 +Negative regulation of interleukin 8 production 0.7710371819960798 0.4513490515603037 0.651737997150406 1.0 1.0 2 P09525 1 +Camera type eye morphogenesis 0.4350215392207708 0.4505388538430689 0.6523219450200635 1.0 1.0 7 P54802 1 +Arachidonic acid secretion 0.7707110241356817 0.450486457109802 0.6523597171704205 1.0 1.0 2 P04083 1 +Positive regulation of fatty acid transport 0.7707110241356734 0.4504864571097804 0.6523597171704361 1.0 1.0 2 P33121 1 +Positive regulation of lipopolysaccharide mediated signaling pathway 0.7707110241356672 0.4504864571097638 0.652359717170448 1.0 1.0 2 P17252 1 +Nucleosome assembly 0.3700136536028346 0.4487998137688493 0.6535760730966729 1.0 1.0 33 P55209,Q99733,P46100,P84243 4 +Positive regulation of endothelial cell migration 0.3467055218074696 0.4484027830901025 0.653862533590365 1.0 1.0 20 Q8WTV0 1 +Regulation of mitochondrial fusion 0.4978562567094342 0.4476414001008307 0.6544120195558987 1.0 1.0 4 Q99536 1 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.7690802348336514 0.4461841981319047 0.6554641963851848 1.0 1.0 2 Q92783 1 +Negative regulation of b cell activation 0.4492327783219091 0.4452468007067756 0.6561414086786492 1.0 1.0 5 Q96IZ0,P07948,Q96FV9,Q16512 4 +Lipid biosynthetic process 0.3146271321254256 0.4440078708285733 0.6570368933883279 1.0 1.0 131 Q9NPH0,Q15126,Q8NBX0,Q16850,O14975,Q96PU8,P33121,O75477,O94788,Q14534,Q9UKU0,Q9UHI6,P37268,O15121,Q8WTV0,O75874,Q99805,Q8NCC3,Q10713,P30536,Q9H4L5,Q15392,Q96G23,Q06136,Q96N66,P48651,Q9BY49,P11802,Q9H3P7 29 +Regulation of phospholipid biosynthetic process 0.4484469021555194 0.4424208646497818 0.6581846834522869 1.0 1.0 5 O75874 1 +Kinetochore organization 0.432337231028823 0.4397801880093254 0.6600963181977941 1.0 1.0 7 P49454,Q9BZD4 2 +Apoptotic process involved in development 0.4953752391293845 0.4394935978867073 0.6603039199095222 1.0 1.0 4 O75312,P30154 2 +Mesenchyme development 0.3709285010828084 0.4386707129794875 0.6609001510434251 1.0 1.0 36 P98172,Q99729,P80723,Q14978,O94788,P08133,Q9NQC3,Q13428 8 +Negative regulation of nuclear division 0.346447851341696 0.4382259551379103 0.6612224953107841 1.0 1.0 17 Q96DY7,P12270,O14777,P53350,Q96GD4,P49454 6 +Response to ketone 0.3706926373253768 0.4371236689484216 0.6620216628756075 1.0 1.0 36 O43823,Q14103,P11802,Q13185,P16435,O95831,Q13126,P16278,P07196,P30536 10 +Regulation of amyloid precursor protein catabolic process 0.3582891499080162 0.4364422510418098 0.6625158897831103 1.0 1.0 15 O95197 1 +Protein autoprocessing 0.4943435582460393 0.4361211989835046 0.6627487972082167 1.0 1.0 4 P17655,Q9Y4W6 2 +Spindle midzone assembly 0.4486343673481008 0.4360531651925032 0.6627981565547267 1.0 1.0 6 Q96GD4 1 +Negative regulation of receptor binding 0.7645140247879869 0.434233863006591 0.664118625070558 1.0 1.0 2 P10586 1 +Calcium ion import into sarcoplasmic reticulum 0.7645140247879856 0.4342338630065873 0.6641186250705606 1.0 1.0 2 O75844 1 +Presynaptic modulation of chemical synaptic transmission 0.7641878669275779 0.433385736819137 0.6647345607751693 1.0 1.0 2 P05771 1 +Regulation of histone h3 k9 methylation 0.4030439829154088 0.4328666379486642 0.6651116583065932 1.0 1.0 9 P46100 1 +Artery morphogenesis 0.4924907234845793 0.4300880465303545 0.6671315949622898 1.0 1.0 4 Q96AY3 1 +Insulin metabolic process 0.4924342617550417 0.4299046741129647 0.6672649852551766 1.0 1.0 4 Q8TAD4 1 +Steroid biosynthetic process 0.3711675733359783 0.429716229816114 0.6674020759331138 1.0 1.0 43 Q9H4L5,Q9UHI6,Q15392,Q15126,P37268,Q16850,O14975,O75477,Q9H3P7,Q14534,P28288,P30536 12 +Regulation of mast cell activation involved in immune response 0.4921923529091896 0.4291193405896973 0.6678363780283418 1.0 1.0 4 O95219,P09601 2 +Regulation of calcium ion transmembrane transport 0.3458904700618088 0.4287359291208382 0.6681154104350384 1.0 1.0 21 P21796 1 +Protein catabolic process in the vacuole 0.446483973736033 0.4281553241460935 0.6685380401546048 1.0 1.0 6 Q8N511,O14773 2 +Lysosomal protein catabolic process 0.446483973736033 0.4281553241460935 0.6685380401546048 1.0 1.0 6 Q8N511,O14773 2 +Protein localization to cell cortex 0.4443651346019359 0.4278403421098979 0.6687673635422839 1.0 1.0 5 P53350 1 +Zinc ion transport 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 1.0 3 Q8TAD4 1 +Regulation of attachment of spindle microtubules to kinetochore 0.4278536627591838 0.4219676569736004 0.6730486251246686 1.0 1.0 7 Q96GD4 1 +Regulation of nik nf kappab signaling 0.3654496989441506 0.4217247894020909 0.6732259082174061 1.0 1.0 13 Q9NYB0,O43657,Q12959 3 +Forebrain regionalization 0.7583170254402993 0.4182462673123824 0.6757670711578436 1.0 1.0 2 P62995 1 +Nuclear transcribed mrna catabolic process exonucleolytic 0.3646214919836025 0.417656621166359 0.6761981924776663 1.0 1.0 13 Q969T7,Q13868 2 +Adhesion of symbiont to host 0.4880947765624838 0.4158968800505868 0.6774854626307407 1.0 1.0 4 Q8WTV0 1 +Meiotic spindle organization 0.4428976332010111 0.4150826159306381 0.6780814250107063 1.0 1.0 6 P46100 1 +Myoblast migration 0.7563600782778854 0.4132538352632974 0.6794206489750787 1.0 1.0 2 P04083 1 +Selective autophagy 0.3559773847304728 0.4131367077713257 0.6795064564821083 1.0 1.0 27 P21796,Q96HY6,Q9Y6I9 3 +Postsynaptic cytoskeleton organization 0.4862251222279421 0.4099146035206066 0.6818685923665968 1.0 1.0 4 Q16352 1 +Negative regulation of cell development 0.337433664310626 0.4096509341164195 0.6820620277938876 1.0 1.0 19 Q9NQC3,P30536 2 +Regulation of multicellular organism growth 0.3879520465094561 0.4095494311351105 0.6821364988590415 1.0 1.0 10 P11802,Q9Y4W6,O75844 3 +Protein localization to cilium 0.3582894615328054 0.4094703320123791 0.6821945347285776 1.0 1.0 14 Q96A65,Q7Z4L5,Q9Y5K8,Q9UPT5,Q10713 5 +Negative regulation of bmp signaling pathway 0.4859660574412519 0.4090882358644283 0.6824749092116964 1.0 1.0 4 Q05D32,Q9UPN9,Q9Y2U8 3 +Negative regulation of mrna 3 end processing 0.4412148922273152 0.4089924025014585 0.6825452366859226 1.0 1.0 6 O75150,Q6PJT7,P18615,Q5VTR2,O00267 5 +Regulation of histamine secretion by mast cell 0.5689097199753634 0.4080100016043581 0.683266332102954 1.0 1.0 3 O95219 1 +Dna methylation 0.3407470382694793 0.4064114892549473 0.6844402792232536 1.0 1.0 17 Q8NB78,P46100,Q9NPF5,O75844 4 +Neuron projection arborization 0.4400132494252278 0.4046607627672973 0.6857268876164082 1.0 1.0 6 Q9HCE1 1 +Thrombin activated receptor signaling pathway 0.5675537025338053 0.4041007314776855 0.6861386470989221 1.0 1.0 3 Q9NWH9 1 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.4227300219967938 0.4018636827489271 0.6877843516786013 1.0 1.0 7 Q8N5M9,Q8N183 2 +Insulin secretion involved in cellular response to glucose stimulus 0.4227300219967938 0.4018636827489271 0.6877843516786013 1.0 1.0 7 Q8N5M9,Q8N183 2 +Calcium ion transmembrane transport 0.3668708449268989 0.3993000032669132 0.6896721647144604 1.0 1.0 42 Q8IYU8,P17252,P08133,P21796,Q9H4I9 5 +Glutamine transport 0.7501630789302017 0.3976265410434806 0.690905493356955 1.0 1.0 2 Q15758 1 +Alanine transport 0.7501630789301953 0.3976265410434643 0.6909054933569669 1.0 1.0 2 P08195 1 +Amyloid beta metabolic process 0.3600606308789782 0.395445214819629 0.6925143458383829 1.0 1.0 13 O95197 1 +Spindle elongation 0.4209431390496523 0.3949178460777991 0.692903519011749 1.0 1.0 7 Q96GD4 1 +Regulation of nucleobase containing compound transport 0.3741374706227802 0.3930152882072345 0.6943081897430696 1.0 1.0 11 Q08J23,Q9ULX6,P12270 3 +Response to fungus 0.4365982051746578 0.3924308013669935 0.6947399313194662 1.0 1.0 6 P46108,P81605 2 +Embryonic skeletal system development 0.4339195979897438 0.3913022282091494 0.69557385204239 1.0 1.0 5 P35222,Q12959 2 +Embryonic skeletal system morphogenesis 0.4339195979897438 0.3913022282091494 0.69557385204239 1.0 1.0 5 P35222,Q12959 2 +Glycoside metabolic process 0.3836740065270776 0.390516244836931 0.6961548453553299 1.0 1.0 10 Q9NUJ1 1 +Positive regulation of cellular amide metabolic process 0.3349560356883872 0.3892252014847485 0.6971095623621859 1.0 1.0 64 Q567V2,Q14011,P67809,A9UHW6,P98179,O15031,O60506,Q9Y2R0,P08670,Q6P087 10 +Membrane protein intracellular domain proteolysis 0.7452707110241232 0.385488402532117 0.6998755972789585 1.0 1.0 2 Q8TCT9 1 +Regionalization 0.3331990887264856 0.3854160261128337 0.6999292108640005 1.0 1.0 19 P17252,O94788 2 +Positive regulation of actin filament polymerization 0.3825124647020408 0.3853905240339339 0.6999481021504141 1.0 1.0 10 P35080,Q9UQB8,Q12959 3 +Regulation of response to wounding 0.3329172079857954 0.3838159854693521 0.7011148391717801 1.0 1.0 19 Q96G23,P46108,Q16625,P10586 4 +Negative regulation of i kappab kinase nf kappab signaling 0.4328397085109259 0.3791117813792044 0.7046048579209432 1.0 1.0 6 Q96CV9 1 +Regulation of cysteine type endopeptidase activity 0.3631543170872542 0.3779284547780958 0.7054837435391683 1.0 1.0 45 P10809,Q15392,O14737,O95831,P51572,Q9Y3B8,Q9P0J0,Q9NR28,Q96F07 9 +Positive regulation of mrna metabolic process 0.34350593957462 0.3767509598624229 0.7063586880589918 1.0 1.0 60 P08621,Q13868,P67809,Q14011,Q969T7,Q92945,P62995,Q9HBH5,Q96E39,P98179,O60506,Q15024,P38159,Q9HCE1 14 +Regulation of epithelial cell migration 0.3632574073045936 0.3764963573188758 0.7065479230594522 1.0 1.0 40 P42785,P17252,Q8WTV0,Q9NQC3 4 +Regulation of alcohol biosynthetic process 0.475528438717793 0.3763267522663995 0.7066739931883275 1.0 1.0 4 O75477 1 +Regulation of cholesterol biosynthetic process 0.475528438717793 0.3763267522663995 0.7066739931883275 1.0 1.0 4 O75477 1 +Positive regulation of lymphocyte apoptotic process 0.7407045009784632 0.3743215477086052 0.7081651026887759 1.0 1.0 2 Q9Y255 1 +Positive regulation of t cell apoptotic process 0.7407045009784632 0.3743215477086052 0.7081651026887759 1.0 1.0 2 Q9Y255 1 +Organophosphate catabolic process 0.3608778852249071 0.3737713499440793 0.7085744365251758 1.0 1.0 36 Q9H773,P00813,Q8WTV0,Q8NCC3,Q10713 5 +Mrna export from nucleus 0.361443728070257 0.3730806387192271 0.7090884281498968 1.0 1.0 37 Q6I9Y2,P22626,Q9BW27,P84103,Q9ULX6,Q99567,P12270,Q86U42,P82979,Q8WUM0,O00148,Q86V81,Q53F19,Q8N1F7,Q08J23,Q12769 16 +Regulation of phospholipase a2 activity 0.4730041280461828 0.3685643075886454 0.7124525037949787 1.0 1.0 4 Q07954,P04083 2 +Rna secondary structure unwinding 0.4722584856396812 0.3662837537610938 0.7141533511500451 1.0 1.0 4 Q08211,O00571,Q9H2U1 3 +Protein localization to cytoplasmic stress granule 0.4290392370416405 0.365798789213694 0.7145152234267456 1.0 1.0 6 P67809 1 +Multicellular organism aging 0.3680749500541028 0.3656831558168954 0.7146015165776842 1.0 1.0 11 P46100 1 +Ribonucleoside triphosphate metabolic process 0.3587330547152475 0.3652966743367105 0.7148899606334835 1.0 1.0 35 P00403,O75964,P00846 3 +Magnesium ion transport 0.7361382909327979 0.3633141491678466 0.7163702249421546 1.0 1.0 2 Q6P4Q7 1 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.3763770902364757 0.35862647906869 0.719874535314325 1.0 1.0 10 P45880 1 +Cardiac muscle cell differentiation 0.3520411946604506 0.3572196908416977 0.7209273459260097 1.0 1.0 13 P02545,O75844 2 +Leukocyte cell cell adhesion 0.3605222717606794 0.3571600857169719 0.720971964842015 1.0 1.0 41 P04439,O43290,P10809,P00813,P98172,Q13464,Q12959,Q96IZ0,P30825,P49366,Q5JRA6,Q08722,P04083 13 +Nucleoside monophosphate biosynthetic process 0.3358565064977853 0.356640205459158 0.7213611745495156 1.0 1.0 22 P00813 1 +Mechanoreceptor differentiation 0.4108494241186755 0.3563534217234435 0.7215759068316672 1.0 1.0 7 P54802 1 +Negative regulation of sprouting angiogenesis 0.7332028701891562 0.3563234935651344 0.7215983171139904 1.0 1.0 2 P57105 1 +Lipid modification 0.3584524491353253 0.3562487468063867 0.7216542887239696 1.0 1.0 48 P42126,P34913,P28288,P23786,P35610,O15254,Q16836,Q9BWD1,O14975,Q96N66,Q16134,Q13011,Q15067,Q10713 14 +Mesenchymal to epithelial transition 0.4689097426454575 0.3561120511006423 0.7217566525857373 1.0 1.0 4 P80723 1 +Very long chain fatty acid metabolic process 0.3757187059069634 0.3557863431047655 0.7220005773878762 1.0 1.0 10 Q15067,Q9UKU0,P33121,O14975 4 +Phospholipid catabolic process 0.3651264240040274 0.3525929308049069 0.7243936380486236 1.0 1.0 11 Q8NCC3,Q8WTV0 2 +Ventricular system development 0.393293847670383 0.3519830849403027 0.7248509480302809 1.0 1.0 8 Q96N66,Q9H6E4 2 +Positive regulation of cell aging 0.4247604061787779 0.3510023994790576 0.7255865482678825 1.0 1.0 6 Q96IZ0,P02545 2 +Insulin processing 0.5482181153956396 0.3500900386134859 0.7262711264724406 1.0 1.0 3 Q8TAD4 1 +Positive regulation of smad protein signal transduction 0.5473992370729428 0.3478769469877435 0.7279325988648857 1.0 1.0 3 Q8N1F7 1 +Regulation of neurotransmitter transport 0.3231300302334832 0.3448880144399151 0.7301785615102512 1.0 1.0 18 Q4J6C6,O14936,P41440,Q9P253,P05771 5 +Mitochondrial outer membrane permeabilization 0.3821024799554414 0.3429370293934637 0.7316458336552554 1.0 1.0 9 P45880 1 +Negative regulation of fat cell differentiation 0.4190462529282202 0.3413549945745651 0.7328363516320557 1.0 1.0 5 Q8N4Q0 1 +Mitotic sister chromatid cohesion 0.3441757695587564 0.3402537379466223 0.7336654526396904 1.0 1.0 14 P41227,P46100,Q9Y6X3 3 +Inflammatory cell apoptotic process 0.4631754639991359 0.3389675874538603 0.7346341476418987 1.0 1.0 4 O75844 1 +Skeletal muscle organ development 0.3412779830092677 0.3374948048195654 0.7357439278180598 1.0 1.0 26 Q92841,P41440,P50402,P80723,O75446 5 +Regulation of membrane lipid distribution 0.3807316122274615 0.3372508639410051 0.7359277969610905 1.0 1.0 9 Q7Z3C6,P08183 2 +Deoxyribonucleotide biosynthetic process 0.4207166080201944 0.3372119958915521 0.735957094944585 1.0 1.0 6 P55263,P31350 2 +Regulation of cell cell adhesion 0.3549061105906151 0.3363771759044542 0.7365864587285227 1.0 1.0 49 P04439,O43290,P10809,P00813,P41440,P98172,Q12959,Q96IZ0,P30825,P49593,P17252,P49366,Q5JRA6,Q08722,P04083 15 +Respiratory system development 0.3366988262929447 0.3352420234075013 0.7374425241802764 1.0 1.0 24 P00813,O94788 2 +Negative regulation of transmembrane transport 0.3270721454213509 0.3327067581241881 0.7393556476720997 1.0 1.0 17 P21796 1 +Histone h3 k9 modification 0.3464555544934573 0.3312637751994381 0.7404452512151221 1.0 1.0 13 P02545,Q03164,P46100 3 +Negative regulation of immune effector process 0.3696045891215631 0.3297199510891729 0.7416115772300467 1.0 1.0 10 P04439,P46108,Q08722 3 +Regulation of cytoplasmic translation 0.3372900063631283 0.3296472554332707 0.741666511898728 1.0 1.0 15 P67809 1 +Regulation of leukocyte migration 0.3398795131361682 0.3295021035028357 0.7417762042786369 1.0 1.0 26 P14174,P46108,P00813,Q9BX67,Q5JRA6,Q08722,P04083 7 +Positive regulation of peptidase activity 0.3555587736697685 0.328850105832691 0.7422689883880265 1.0 1.0 39 P10809,O14737,O95831,P51572,Q9P0J0,Q9NR28,Q96F07,Q96HY6 8 +Regulation of hormone metabolic process 0.4150359483413059 0.3283374488044652 0.7426565321447369 1.0 1.0 5 O75844 1 +Negative regulation of cellular response to growth factor stimulus 0.3785576988768346 0.3282886668089139 0.7426934123592972 1.0 1.0 9 O14964,O14936 2 +Histone phosphorylation 0.3279585195386501 0.3264561138402452 0.7440792880963631 1.0 1.0 21 O43823,P05771,P17252,Q96GD4 4 +Pyrimidine deoxyribonucleotide biosynthetic process 0.5386166437760412 0.3245401636089053 0.7455291201075547 1.0 1.0 3 P23919 1 +Regulation of establishment of planar polarity 0.45822454308093 0.3244507729400543 0.7455967855970806 1.0 1.0 4 Q8TAA9,P60953,Q13308 3 +Regulation of protein localization to cell cortex 0.4572733081666694 0.3216926202327903 0.747685569118965 1.0 1.0 4 P53350 1 +Regulation of glucose import 0.3765466818986062 0.3200590543892935 0.7489235641438807 1.0 1.0 9 P52789 1 +Negative regulation of single stranded viral rna replication via double stranded dna intermediate 0.4560899647533573 0.318275597048458 0.7502758933507181 1.0 1.0 4 Q9UK61,Q9Y6X9 2 +Mitophagy 0.3393562934420386 0.3174671170722277 0.750889186740952 1.0 1.0 14 P21796 1 +Nad metabolic process 0.3345987856786194 0.3165744994852766 0.7515664877365107 1.0 1.0 15 P52789 1 +Plasma membrane organization 0.3394827036894757 0.3162440407582358 0.7518172820164613 1.0 1.0 27 O15121,P41440,P08133,Q9UQB8 4 +Neural tube formation 0.3294670868609489 0.316231884356125 0.7518265083466791 1.0 1.0 16 P17252 1 +Axis specification 0.399838975570995 0.3156801896658042 0.7522452647285429 1.0 1.0 7 P35222,Q9UK61,Q99496,P80723 4 +Positive regulation of nucleocytoplasmic transport 0.3466317583539911 0.3115352157386789 0.7553937756088915 1.0 1.0 32 O00459,P50402,Q9BVS4,P12270,Q9NW64,Q9Y3B8,Q9NPF5,P17252,Q14012 9 +Cellular response to salt 0.7136333985648917 0.3114868778028511 0.7554305170665649 1.0 1.0 2 P09651 1 +Cellular response to sodium arsenite 0.7136333985648917 0.3114868778028511 0.7554305170665649 1.0 1.0 2 P09651 1 +Regulation of establishment of protein localization to mitochondrion 0.3229602144569576 0.3113399603421901 0.7555421917937988 1.0 1.0 17 P55786,Q9UII2 2 +Negative regulation of autophagy 0.3343373412945753 0.3098415921661894 0.7566814209796549 1.0 1.0 25 Q9P275,Q08379,P08621,O15118,P85037,P30536 6 +Histone h4 k16 acetylation 0.3738757712577079 0.3092216492609149 0.7571529266396801 1.0 1.0 9 O75844 1 +Muscle structure development 0.2717107234198336 0.3075672706466193 0.7584116279097932 1.0 1.0 91 P84243,Q7Z4V5,Q9Y5Q8,Q96PU8,P85037,O43707,P17655,O75844,P67809,P46939,Q8IV08,P50402,Q9P2K5,P80723,P02545,P16615,Q96HC4,O75446,Q14012,Q9BWF3,P30626,Q92841,P41440,Q14331,Q9Y4W6,Q99523,P49454 27 +Cellular response to ketone 0.3162062540658651 0.3074491241100622 0.7585015419127079 1.0 1.0 18 O43823,Q13185,O95831 3 +Neurotransmitter catabolic process 0.7113502935420608 0.3064618684317944 0.7592530085579574 1.0 1.0 2 P21964 1 +Positive regulation of membrane permeability 0.3443909426206142 0.3059548732366448 0.7596390050884212 1.0 1.0 12 Q9BX67,P45880,Q9UII2 3 +Establishment of protein localization to organelle 0.3385323371235295 0.3045725654082069 0.760691717463541 1.0 1.0 181 Q9P275,Q99595,O60830,Q5JRX3,P52292,Q9Y5M8,Q15717,Q15070,O14964,Q9UII2,Q9NPF5,Q14108,Q9P0J0,Q8N4Q1,P55786,Q92783,P62072,Q3ZCQ8,Q9NS69,Q8N4H5,P61970,O43765,O14925,Q8NFH5,O95831,Q14978,Q9NW64,P51572,P52789,Q7L5D6,O75381,P40855,P56589,P78371,Q10713,P30536,O00459,P10809,Q9Y276,O00170,O14737,Q9Y584,P12270,P02545,Q92973,Q8N1F7,P46379,Q15629,Q99523 49 +Meiotic chromosome segregation 0.3182807729117941 0.3031981342589889 0.7617388707837933 1.0 1.0 19 P46379,Q92791,P53350,Q9BTX1 4 +Pointed end actin filament capping 0.7097195042400486 0.3028995757825234 0.7619663946534423 1.0 1.0 2 Q9NYL9 1 +Response to muscle activity 0.5300411448649944 0.3024786097936289 0.7622872371510785 1.0 1.0 3 Q9UDX5 1 +Endodermal cell differentiation 0.3959490362626597 0.3016838112442175 0.7628931103855452 1.0 1.0 7 P07942,P35222,Q8N7H5,Q6PD62,O75367,Q92541 6 +Endoderm formation 0.3959490362626597 0.3016838112442175 0.7628931103855452 1.0 1.0 7 P07942,P35222,Q8N7H5,Q6PD62,O75367,Q92541 6 +Regulation of inflammatory response 0.3488307614472721 0.2990621672033827 0.7648926121624344 1.0 1.0 36 P00813 1 +Camera type eye development 0.3415649613469785 0.2986891510172649 0.7651772356257502 1.0 1.0 30 P08670,P54802,O94788,Q16706 4 +Lipid translocation 0.379850347221441 0.2982343886871824 0.7655242769477693 1.0 1.0 8 P08183 1 +Organic anion transport 0.3494347200510233 0.2978971690250639 0.765781648706876 1.0 1.0 49 Q9Y619,P08195,Q8TB61,P30825,Q8TDW0,Q96NB2,Q08722,Q9UBX3,P28288,P04083,P14174,O15439,Q9Y6M7,P53985,P07602,Q99808,P41440,Q15758,Q02978,Q9BQT8,Q9H9B4 21 +Chloride transmembrane transport 0.3948745776010637 0.2978536697311935 0.7658148499882125 1.0 1.0 7 Q9UHG3 1 +Potassium ion import across plasma membrane 0.3947094894862366 0.2972665717754663 0.7662630005729636 1.0 1.0 7 Q9Y666,Q12959 2 +Platelet derived growth factor receptor signaling pathway 0.3791780161471735 0.2956125575599768 0.767525982491279 1.0 1.0 8 O14964,O95470,Q07954 3 +Nuclear body organization 0.5272430668841601 0.2954399734851168 0.767657800897851 1.0 1.0 3 O75312,Q8NC51 2 +Rrna 3 end processing 0.4080622224320709 0.2953359435804167 0.767737261396586 1.0 1.0 6 Q13868 1 +Protoporphyrinogen ix biosynthetic process 0.4469989873713019 0.2925582999133318 0.7698597915910252 1.0 1.0 4 P50336 1 +Regulation of production of small rna involved in gene silencing by rna 0.3928112302086803 0.2905427578926964 0.771401044694529 1.0 1.0 7 P17844,P04637,O75844 3 +Transition between fast and slow fiber 0.7038486627527671 0.2902633881285046 0.7716147457061209 1.0 1.0 2 P16615 1 +Regulation of cardiac muscle adaptation 0.7038486627527566 0.2902633881284823 0.771614745706138 1.0 1.0 2 P02545 1 +Glycerolipid biosynthetic process 0.3481280052965538 0.290018541529412 0.7718020528300573 1.0 1.0 37 Q8NCC3,Q8WTV0,Q9NPH0 3 +Positive regulation of fibroblast proliferation 0.4457518672254958 0.2891055611920045 0.7725005980175976 1.0 1.0 4 P11802 1 +Chemical homeostasis 0.3351044056266645 0.2870749401598313 0.7740549398031491 1.0 1.0 178 Q15904,P34913,Q15043,P42785,P30519,P85037,Q9Y3B8,Q93050,Q15067,Q9H4I9,Q9Y6C9,Q8TAD4,P35610,O15254,Q8WTV0,P17252,P52789,P51572,P05771,Q9NQC3,P30536,Q6P4Q7,Q96TC7,Q9Y666,O15260,Q9HD20,Q9Y6M7,P08133,Q8N511,P53985,Q8IYU8,Q99808,Q9BPX6,Q8N183,P62995,O15118,P17480 37 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.3591770283471298 0.2866244956065649 0.7743998562658234 1.0 1.0 10 P45880 1 +Negative regulation of androgen receptor signaling pathway 0.4445169712793697 0.2857049072648839 0.7751041458495085 1.0 1.0 4 Q96EB6,O75928,P35232 3 +Glycoprotein metabolic process 0.3396762413698758 0.285458673186512 0.775292761771224 1.0 1.0 56 P04843,P04844,Q92542,Q96IZ0,Q9NY61,Q10472,O60701,Q9Y5P6,P35610,Q9BT22,Q86SF2,Q8NAT1,Q99805,O94923,Q16706,Q9NQX7,Q7LGA3,O60502,Q2TAA5,Q08379,P46977,O15118,Q8TCJ2 23 +Positive regulation of cell death 0.2851234831232288 0.2818290394752225 0.7780746028336447 1.0 1.0 110 Q9Y6C9,Q9NQX7,P10809,Q9Y255,Q9NS69,P00403,O14737,O95831,P98175,P51572,O94788,Q99956,Q9NR28,Q7Z3C6,P52756,P30536 16 +Cotranslational protein targeting to membrane 0.3308824397528747 0.2785583388384078 0.7805837883597162 1.0 1.0 14 Q15629 1 +Dna packaging 0.2615168202389549 0.2760744809073597 0.7824908605537431 1.0 1.0 82 O43823,Q9HD42,Q9ULX6,Q8NEY8,P84243,P41227,Q8IY18,Q13185,P10412,P46100,O95831,P12270,Q01105,Q9Y6X9,P55209,P53350,Q99733 17 +Regulation of cell population proliferation 0.3475334057473382 0.2759399114355239 0.7825942186111485 1.0 1.0 199 P00813,P57105,O14936,P98172,P30825,Q00577,Q9Y3B8,O94788,P43490,P55209,Q9UII2,Q14534,Q08722,Q9NR77,O75844,P22392,Q14978,P17252,P52756,Q9NQC3,P30536,O95684,Q15392,Q96G23,P50402,Q14004,O14737,Q96DY7,P02545,Q32P28,Q96HY6,P11802,P43307,P98175 34 +Anterior posterior axis specification 0.4014875931904051 0.2743872479274543 0.7837870417764317 1.0 1.0 6 P80723,Q9UK61,Q99496 3 +Folic acid metabolic process 0.4010423335426438 0.2729893904066919 0.7848613711691028 1.0 1.0 6 Q8IYS1,P41440 2 +Mesonephric tubule morphogenesis 0.6950424005218447 0.271869282046181 0.7857225312722802 1.0 1.0 2 Q12959 1 +Actomyosin contractile ring organization 0.438872794153535 0.2703961802253626 0.7868554784331967 1.0 1.0 4 Q9H0H5,Q8WUM4 2 +De novo protein folding 0.3147775330758173 0.270103670097241 0.7870804986892723 1.0 1.0 20 P10809,P48723,Q99615,Q8N4Q1,P78371 5 +Cell fate commitment involved in formation of primary germ layer 0.3956904995102862 0.2684671366767166 0.7883397677804962 1.0 1.0 5 P35222,Q6PD62,Q8N7H5,Q92541 4 +Endodermal cell fate commitment 0.3956904995102862 0.2684671366767166 0.7883397677804962 1.0 1.0 5 P35222,Q6PD62,Q8N7H5,Q92541 4 +Histone h2b ubiquitination 0.395690499510284 0.2684671366767105 0.7883397677805009 1.0 1.0 5 Q8N7H5,Q5VTR2,Q6PD62,O75150 4 +Polyadenylation dependent rna catabolic process 0.3993457537172439 0.2676878256283785 0.7889396216735145 1.0 1.0 6 Q13868 1 +Import into cell 0.3334165164219344 0.2620788169827763 0.7932606777451596 1.0 1.0 29 Q9Y666,Q99808,P41440,Q15043,O14975,P30825,Q8TDW0 7 +Peptidyl proline modification 0.3390704781188283 0.2602840499323446 0.7946446750202159 1.0 1.0 33 Q32P28,Q96AY3,Q9NWM8 3 +Receptor metabolic process 0.341110863007856 0.258865205807657 0.7957392450495167 1.0 1.0 35 P42892,Q96CV9,P41440 3 +Regulation of peptidyl lysine acetylation 0.3067294587390202 0.2581856248193916 0.7962636516553436 1.0 1.0 18 Q03164,Q01105,Q14012,O75844 4 +Plasma membrane phospholipid scrambling 0.4337384690883837 0.2568105635533507 0.7973250149690858 1.0 1.0 4 Q7Z3C6 1 +Epithelial tube branching involved in lung morphogenesis 0.6872146118721415 0.2560939659977024 0.7978782811022045 1.0 1.0 2 P35222 1 +Regulation of protein localization to synapse 0.6872146118721376 0.2560939659976949 0.7978782811022103 1.0 1.0 2 Q12959 1 +Intermediate filament bundle assembly 0.5105664194397933 0.2551840972948892 0.7985809130884542 1.0 1.0 3 P07197 1 +Macromolecule deacylation 0.3392095306007749 0.2541889235307956 0.7993496073864967 1.0 1.0 34 O43823,Q9UMR5,Q9NUJ1,Q96PK6 4 +Cellular response to inorganic substance 0.3402998990529731 0.2541713844974522 0.799363156671056 1.0 1.0 35 P30536,O95831 2 +Regulation of dna templated transcription elongation 0.3240902053292444 0.254113565511489 0.7994078235224533 1.0 1.0 25 Q14004,Q8IXH7 2 +Production of molecular mediator involved in inflammatory response 0.325310896088501 0.2538304282941256 0.7996265647460576 1.0 1.0 14 Q8IV08 1 +Negative regulation of peptide secretion 0.3680318571577767 0.2531376187778707 0.8001618697293145 1.0 1.0 8 Q16836,Q8N183 2 +Negative regulation of hormone secretion 0.3680318571577767 0.2531376187778707 0.8001618697293145 1.0 1.0 8 Q16836,Q8N183 2 +Positive regulation of endothelial cell chemotaxis 0.6849315068493074 0.2515962348932231 0.8013531691494606 1.0 1.0 2 Q9NWH9 1 +Regulation of endothelial cell chemotaxis 0.6849315068493074 0.2515962348932231 0.8013531691494606 1.0 1.0 2 Q9NWH9 1 +Glucose import 0.33146506230437 0.251328951468479 0.8015597933192073 1.0 1.0 12 Q16625,P52789 2 +Protein localization to adherens junction 0.3898139079333976 0.2512985786269566 0.8015832740045106 1.0 1.0 5 Q5T2T1,Q13112,Q14160,Q07157 4 +Regulation of defense response to virus 0.3204085538064364 0.2502924860614268 0.8023611668377302 1.0 1.0 15 O43657 1 +Antigen receptor mediated signaling pathway 0.3159278891432071 0.2486712922286836 0.8036150568762541 1.0 1.0 22 P00813 1 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.3878550440744425 0.2456865968786034 0.8059248483859007 1.0 1.0 5 O00330,P08559,P09622,P11177 4 +Negative regulation of telomere maintenance 0.3267791707827756 0.2447392260748833 0.8066583534480904 1.0 1.0 13 P07910,P09651 2 +Amino acid transmembrane transport 0.3139440409536766 0.2415699970935509 0.8091133724609989 1.0 1.0 16 Q9Y619,P08195,Q15758,P30825,Q8TDW0,Q9H9B4,Q96NB2 7 +Inner cell mass cell proliferation 0.3854075269453797 0.2387539356023178 0.811296391339257 1.0 1.0 5 Q9BRT9 1 +Negative regulation of translational initiation 0.3638921644137762 0.2378599775633377 0.8119896979568577 1.0 1.0 8 Q9BWF3,P12270 2 +Endoplasmic reticulum plasma membrane tethering 0.502446982055456 0.2366713538510002 0.812911759956731 1.0 1.0 3 A0FGR8,O95292 2 +Endoplasmic reticulum localization 0.502446982055456 0.2366713538510002 0.812911759956731 1.0 1.0 3 A0FGR8,O95292 2 +Neuron projection regeneration 0.3371180396368166 0.2357483355612926 0.8136279604299337 1.0 1.0 11 Q96G23,P30536 2 +Regulation of myoblast differentiation 0.5011419249592082 0.2337640955384804 0.8151681249358769 1.0 1.0 3 Q8IWT6,Q14254 2 +Exocyst localization 0.6738421395955525 0.2304236738660435 0.8177625669500592 1.0 1.0 2 O60645 1 +Regulation of dna topoisomerase atp hydrolyzing activity 0.499510603588895 0.2301569325532142 0.817969826351463 1.0 1.0 3 Q00839,Q96T88 2 +Regulation of isomerase activity 0.499510603588895 0.2301569325532142 0.817969826351463 1.0 1.0 3 Q00839,Q96T88 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.4994297269781027 0.2299788790774574 0.8181081819201628 1.0 1.0 3 P04439 1 +Translational readthrough 0.6731898238747399 0.2292133040054756 0.8187031327249499 1.0 1.0 2 P57772 1 +Positive regulation of execution phase of apoptosis 0.67253750815394 0.2280068571519022 0.8196409096860775 1.0 1.0 2 P04637 1 +Positive regulation of blood vessel endothelial cell migration 0.3440638266398108 0.2275168774838737 0.8200218469881873 1.0 1.0 10 P04083,P17252,P06576,P09601 4 +Regulation of cd8 positive alpha beta t cell activation 0.6715590345727178 0.2262045506939149 0.8210423313965394 1.0 1.0 2 P04439 1 +Positive regulation of cd8 positive alpha beta t cell activation 0.6715590345727178 0.2262045506939149 0.8210423313965394 1.0 1.0 2 P04439 1 +Cd8 positive alpha beta t cell activation 0.6715590345727178 0.2262045506939149 0.8210423313965394 1.0 1.0 2 P04439 1 +Purine containing compound biosynthetic process 0.2890339680031459 0.2258295444968956 0.8213339974047467 1.0 1.0 73 P00813,P00403,O75964,P22392,Q13126,P00846,Q9UMR5 7 +Protein targeting to membrane 0.331491601289178 0.2255032841532726 0.8215877707787962 1.0 1.0 32 O60725,Q15629,O43765,Q9H173,P43307,Q99442,Q7L5D6,P40855,P56589,P46379 10 +Neutrophil differentiation 0.4204411392252645 0.2231863595589101 0.8233904677047896 1.0 1.0 4 Q8N5M9 1 +Regulation of sister chromatid cohesion 0.3426701053899185 0.2222813496448814 0.8240948697839521 1.0 1.0 10 P41227,P46100,P23246 3 +Regulation of bmp signaling pathway 0.3510951291271602 0.2214539990256775 0.8247389508248795 1.0 1.0 9 Q05D32,Q9C0C9,Q9Y2U8,Q14980,Q8NC56,Q9BRX2,Q9UPN9,Q14318 8 +Dna methylation or demethylation 0.3077001674303508 0.220351352379375 0.825597529410208 1.0 1.0 21 Q8NB78,P46100,Q9NPF5,O75844 4 +Cell communication by electrical coupling 0.3585972649918587 0.2187336874272049 0.826857505578146 1.0 1.0 8 P17252 1 +Negative regulation of rho protein signal transduction 0.3781323359631763 0.2186764632641165 0.8269020848472663 1.0 1.0 5 Q9NWH9,P63167 2 +Tripartite regional subdivision 0.493860499594683 0.2178964324980477 0.8275098068220892 1.0 1.0 3 P80723 1 +Blastoderm segmentation 0.493860499594683 0.2178964324980477 0.8275098068220892 1.0 1.0 3 P80723 1 +Mrna cleavage involved in mrna processing 0.3580838027903352 0.2169043319594147 0.8282829015576343 1.0 1.0 8 Q6UN15,Q8N684 2 +Positive regulation of cold induced thermogenesis 0.3321115277074408 0.2164551333909379 0.828632994483633 1.0 1.0 11 Q16836,P23786 2 +Positive regulation of epithelial cell migration 0.3248662981000628 0.2160065289229409 0.828982658358351 1.0 1.0 29 Q8WTV0,P17252 2 +Ncrna transcription 0.3141932050003019 0.2147796710005146 0.8299391032179795 1.0 1.0 24 P46100 1 +Positive regulation of neurotransmitter uptake 0.6650358773646373 0.2144158404392333 0.8302227900177754 1.0 1.0 2 P20337 1 +Leukocyte tethering or rolling 0.6650358773646367 0.2144158404392324 0.8302227900177761 1.0 1.0 2 Q13464 1 +Leukocyte adhesion to vascular endothelial cell 0.6650358773646367 0.2144158404392324 0.8302227900177761 1.0 1.0 2 Q13464 1 +Cellular defense response 0.665035877364635 0.2144158404392293 0.8302227900177785 1.0 1.0 2 Q08380 1 +Tumor necrosis factor superfamily cytokine production 0.3028133300138442 0.2127932516320381 0.8314882276219397 1.0 1.0 17 P30536 1 +Positive regulation of mitochondrial fission 0.369487095720356 0.2122288169080145 0.8319285261222564 1.0 1.0 7 Q9NQG6,O00429,Q96HS1,Q8NE86,P11233,Q9GZY8 6 +Retinal ganglion cell axon guidance 0.4157963446475243 0.2119885361814371 0.8321159778824949 1.0 1.0 4 O94813,Q13740,Q15375 3 +Spliceosomal tri snrnp complex assembly 0.3309104360216062 0.2119052735221214 0.8321809363486217 1.0 1.0 11 Q9UHI6,O75494 2 +Negative regulation of immune system process 0.3376838611786785 0.2118554958782574 0.8322197715840214 1.0 1.0 42 P00813 1 +Placenta blood vessel development 0.4154699738903393 0.211212599269465 0.8327213797256663 1.0 1.0 4 Q15738,P28482,Q96T37 3 +Proximal tubule development 0.662426614481392 0.20981120075935 0.8338150306957373 1.0 1.0 2 P35610 1 +Intermediate filament organization 0.3791458679598802 0.207709962219159 0.8354554386001853 1.0 1.0 6 P07197,P08670 2 +Organ growth 0.2961867427628339 0.2063479500427095 0.8365191256556428 1.0 1.0 18 P07602,O75844,P16435,P08133,Q99956 5 +Negative regulation of chromosome organization 0.3336386317067219 0.2052605912380965 0.8373685321137287 1.0 1.0 37 P84243,P41227,P46100,P12270,Q9NYB0,P07910,Q96GD4,P49454,P09651 9 +Fatty acid beta oxidation 0.3324230248117517 0.2037485910119618 0.8385499684347923 1.0 1.0 36 P42126,P23786,P35610,O15254,Q16836,Q9BWD1,O14975,Q16134,Q13011,Q15067 10 +Snrna processing 0.3190382344510106 0.2021893244895548 0.8397687186063165 1.0 1.0 12 Q68E01,Q13868 2 +Neurotransmitter reuptake 0.4109663029072805 0.2006527422326543 0.8409701143168362 1.0 1.0 4 P20337,Q99808 2 +Myotube cell development 0.4854812398042278 0.2003883362163207 0.8411768808429652 1.0 1.0 3 Q08209,Q15149 2 +Regulation of t cell migration 0.4854437445587014 0.2003118223430798 0.8412367170318928 1.0 1.0 3 P46108 1 +Fibroblast proliferation 0.318413846704876 0.1998137594663234 0.8416262398337233 1.0 1.0 12 P14174,O75844,P50402,P11802,Q96IZ0 5 +Leukocyte proliferation 0.3333217391392581 0.1987890476425629 0.8424277637292432 1.0 1.0 38 P04439,P14174,P10809,P00813,P98172,Q92542,Q12959,Q96IZ0,P30825,Q00577,P49366,P04083 12 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.311989284799434 0.1976906161199609 0.8432871320737767 1.0 1.0 14 P07602 1 +Positive regulation of telomere capping 0.3687742765146822 0.1940496813018664 0.8461369811166146 1.0 1.0 5 Q96GD4 1 +Muscle cell differentiation 0.3240531127266084 0.1930071078729228 0.8469534014776396 1.0 1.0 58 Q9BWF3,O43707,P17655,Q8IV08,P84243,O75844,Q7Z4V5,P41440,Q9P2K5,P67809,Q96PU8,Q9Y4W6,P02545,P16615,Q96HC4,Q99523,Q14012 17 +Apoptotic process involved in morphogenesis 0.6523157208088599 0.1925704805099934 0.8472953653157804 1.0 1.0 2 P30154 1 +Metanephros morphogenesis 0.4807416591016413 0.1908470739556343 0.8486454067547151 1.0 1.0 3 P80723 1 +Striated muscle cell differentiation 0.3317476943530296 0.1899442207100099 0.8493528400797772 1.0 1.0 38 P41440,Q8IV08,P67809,O75844 4 +Histone h3 k14 acetylation 0.3725875079606385 0.1895493993959946 0.8496622416484274 1.0 1.0 6 Q03164 1 +Sister chromatid cohesion 0.3136607341617505 0.1893318137754721 0.8498327624349502 1.0 1.0 26 P41227,P46100,Q8WVM7,P53350,P23246,Q9Y6X3,Q8N3U4 7 +Astral microtubule organization 0.3667385355992211 0.1888755482373918 0.8501903583064785 1.0 1.0 5 Q12959 1 +Renal sodium excretion 0.6500326157860319 0.1888104541750694 0.85024137797135 1.0 1.0 2 Q9Y5X3 1 +Regulation of renal system process 0.6500326157860319 0.1888104541750694 0.85024137797135 1.0 1.0 2 Q9Y5X3 1 +Positive regulation of renal sodium excretion 0.6500326157860319 0.1888104541750694 0.85024137797135 1.0 1.0 2 Q9Y5X3 1 +Renal tubular secretion 0.6500326157860319 0.1888104541750694 0.85024137797135 1.0 1.0 2 Q9Y5X3 1 +Regulation of excretion 0.6500326157860319 0.1888104541750694 0.85024137797135 1.0 1.0 2 Q9Y5X3 1 +Regulation of steroid hormone biosynthetic process 0.6497064579256191 0.1882773194773911 0.8506592638366157 1.0 1.0 2 P16435 1 +Regulation of hormone biosynthetic process 0.6497064579256191 0.1882773194773911 0.8506592638366157 1.0 1.0 2 P16435 1 +Peptidyl cysteine modification 0.3617410238710288 0.188114783203056 0.8507866726568003 1.0 1.0 7 Q8N4Q1 1 +Peptide transport 0.3257141651011247 0.186863321078135 0.8517677981338985 1.0 1.0 33 Q03519,O15439,P53985,Q16836 4 +G protein coupled acetylcholine receptor signaling pathway 0.6480756686236052 0.1856267007106657 0.852737513325361 1.0 1.0 2 P04899 1 +Cell activation involved in immune response 0.3300524983437973 0.1853093839778821 0.852986378150477 1.0 1.0 37 Q9UQ84,P10809,P00813,O95219,Q96FZ2,O96028 6 +Positive regulation of protein k63 linked ubiquitination 0.6474233529027984 0.1845734812787557 0.8535635874086238 1.0 1.0 2 O00571 1 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.3646751550767261 0.1836990406641311 0.8542495615413515 1.0 1.0 5 Q9NPA0,Q15006,Q8N766,O43402 4 +Positive regulation of exocytosis 0.3048518772105177 0.1833022924377484 0.8545608357684249 1.0 1.0 15 Q92783,P20339,O95219,O14964,P51151,Q99816 6 +Phosphatidylcholine biosynthetic process 0.4020887728459634 0.1806537477657535 0.8566393652706661 1.0 1.0 4 Q6IAN0,Q8NF37,P17655 3 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4752627371545875 0.1801472089803913 0.8570370014109416 1.0 1.0 3 P51572 1 +Transepithelial transport 0.4014820234897432 0.1793269301812894 0.8576810023565962 1.0 1.0 4 P08183 1 +Negative regulation of production of molecular mediator of immune response 0.6435094585779428 0.1783385609573532 0.8584570969169487 1.0 1.0 2 P09601 1 +Cell cell adhesion involved in gastrulation 0.6425309849967293 0.1768024478096176 0.8596635662721694 1.0 1.0 2 Q9H4A3 1 +Regulation of mitochondrial dna replication 0.473083197389867 0.1759897379231487 0.8603020045686476 1.0 1.0 3 Q04837,Q9UJZ1 2 +Release of sequestered calcium ion into cytosol by endoplasmic reticulum 0.3576579269822821 0.1758113151560533 0.8604421798961939 1.0 1.0 7 P17252 1 +Trna catabolic process 0.3379614226691225 0.1750652235865113 0.8610283837906059 1.0 1.0 9 Q15024,Q13868 2 +Posttranslational protein targeting to membrane translocation 0.3994778067885137 0.1749809376720798 0.8610946120247818 1.0 1.0 4 Q99442,Q9UGP8,P61619 3 +Regulation of lymphocyte migration 0.360992499464789 0.1746314433238953 0.8613692400182094 1.0 1.0 5 Q5JRA6,P46108 2 +Nadh metabolic process 0.2922807814249708 0.1740177757120182 0.8618514923708447 1.0 1.0 19 P52789 1 +Tissue regeneration 0.3569806538133201 0.1737983122638846 0.8620239708270083 1.0 1.0 7 Q7Z4V5,Q08209,P04083 3 +Positive regulation of chromosome segregation 0.3666597584129482 0.1737179162645126 0.8620871564709072 1.0 1.0 6 Q96GD4 1 +Neutrophil homeostasis 0.4709181308810282 0.1719159146241581 0.8635036348016794 1.0 1.0 3 Q9BX67 1 +Skeletal system development 0.3310558637543093 0.1712475830936513 0.8640290941528193 1.0 1.0 43 Q15904,O75844,O96028,Q96HY6,Q15043,P16435,Q92896,Q32P28,P08133,Q7Z3C6,Q13428 11 +Positive regulation of bmp signaling pathway 0.3971932114882564 0.1700960344684804 0.8649346121084096 1.0 1.0 4 Q14980,Q9BRX2,Q9C0C9 3 +Response to interferon beta 0.3589993963702986 0.1698162286863701 0.8651546636564167 1.0 1.0 5 Q9P0J0 1 +Cellular response to interferon beta 0.3589993963702986 0.1698162286863701 0.8651546636564167 1.0 1.0 5 Q9P0J0 1 +Pyrimidine deoxyribonucleoside metabolic process 0.637964774951065 0.1697535913898858 0.8652039258085269 1.0 1.0 2 P23919 1 +Cellular response to xenobiotic stimulus 0.3049495329881195 0.1695926321462082 0.8653305173066408 1.0 1.0 24 O00170,P07099,P16435,O14974,P33121,Q9NW64,O43169 7 +Positive regulation of dna methylation dependent heterochromatin assembly 0.3646616659217735 0.1685087425255432 0.8661830664751962 1.0 1.0 6 Q9UK61,Q9Y6X9,Q8NEY8 3 +Negative regulation of cellular respiration 0.4681892332789467 0.1668609756273306 0.8674794395302718 1.0 1.0 3 P30405,Q12931 2 +Response to arsenic containing substance 0.3040007235802749 0.1661945261689843 0.8680038670288863 1.0 1.0 14 Q9BWF3,O00571,Q9UER7,P36551,P09601,P07196,P09651,Q96QD8 8 +Cell cycle g2 m phase transition 0.3299123527602012 0.1646294690379663 0.8692356347538228 1.0 1.0 43 O43823,Q68E01,P11802,P08183,Q96GD4,Q96JB5 6 +Regulation of leukocyte differentiation 0.3102359498930106 0.1620336563969811 0.8712793500977889 1.0 1.0 27 O96005,P00813,P17252 3 +Urogenital system development 0.3266194833089755 0.1617228759454031 0.8715240892788301 1.0 1.0 38 P07602,O75844,P35610,P80723,O94788,P49454,P46379,Q12769 8 +Regulation of morphogenesis of an epithelium 0.6324200913241911 0.161459218619505 0.8717317287083062 1.0 1.0 2 P35222 1 +Regulation of synaptic vesicle exocytosis 0.3051542066486858 0.1597988508799654 0.8730395293145783 1.0 1.0 13 P05771,Q4J6C6,Q9P253,O14936 4 +Negative regulation of excitatory postsynaptic potential 0.6311154598825739 0.1595498038511186 0.873235723017012 1.0 1.0 2 P38919 1 +Astrocyte development 0.3917228516810538 0.1587003575260983 0.8739049564833365 1.0 1.0 4 P08670 1 +Cellular response to topologically incorrect protein 0.3215496634265902 0.1580369487748348 0.8744276836365128 1.0 1.0 34 Q96HY6,P10809,P48723,Q96JB5 4 +Epithelial tube formation 0.2855812582771245 0.1576797498591076 0.8747091581278252 1.0 1.0 18 P17252 1 +Complement activation 0.4626427406198948 0.1568620498919914 0.8753535693287937 1.0 1.0 3 Q99623,P35232 2 +Regulation of complement activation 0.4626427406198948 0.1568620498919914 0.8753535693287937 1.0 1.0 3 Q99623,P35232 2 +Regulation of humoral immune response 0.4626427406198948 0.1568620498919914 0.8753535693287937 1.0 1.0 3 Q99623,P35232 2 +Regulation of protein acetylation 0.2943079147658331 0.1568497121669955 0.8753632930501909 1.0 1.0 21 O75844,Q03164,Q9NYB0,Q01105,Q14012 5 +G protein coupled receptor signaling pathway involved in heart process 0.6291585127201481 0.1567157959800257 0.8754688375184849 1.0 1.0 2 P04899 1 +Salivary gland development 0.6291585127201463 0.1567157959800231 0.8754688375184869 1.0 1.0 2 Q14118 1 +Cardiac conduction system development 0.6291585127201453 0.1567157959800217 0.875468837518488 1.0 1.0 2 Q14126 1 +Heterotypic cell cell adhesion 0.3241247804240973 0.1563856562817911 0.875729042697762 1.0 1.0 10 Q14126,Q9BX67,Q08722,P41440 4 +Protein trimerization 0.390298032833047 0.1558023147569085 0.876188845997226 1.0 1.0 4 P14174,Q15758 2 +Embryonic axis specification 0.3530001719480858 0.1557179595638025 0.8762553401762372 1.0 1.0 5 P80723,Q9UK61 2 +Entry into host 0.3147662115854217 0.1554117243138539 0.8764967417989626 1.0 1.0 30 P42566,P08195,Q9BTY2,Q9P253,O15118,Q8WTV0,Q14108,Q9UPT5 8 +Negative regulation of cellular protein catabolic process 0.3128604813290247 0.1551706226970845 0.8766868074343048 1.0 1.0 29 O43765,Q96KB5,Q92530,Q96HY6,Q9UL15,P46379,Q96JB5 7 +Maintenance of blood brain barrier 0.3398524888416352 0.155024571472029 0.8768019462428016 1.0 1.0 8 Q16625 1 +Positive regulation of vesicle fusion 0.6278538812785268 0.1548465194007539 0.8769423162966568 1.0 1.0 2 P04083 1 +Base excision repair ap site formation 0.6265492498369046 0.1529932793340264 0.8784035752113999 1.0 1.0 2 P78549 1 +Negative regulation of telomere maintenance via telomerase 0.3309381800015215 0.15165532393626 0.8794587958215458 1.0 1.0 9 P07910 1 +Chondroitin sulfate proteoglycan metabolic process 0.6255707762556973 0.151613865647242 0.879491496635201 1.0 1.0 2 O60701 1 +Ear development 0.2930226884095316 0.1510646319516897 0.8799247318825354 1.0 1.0 21 P42892 1 +Atp synthesis coupled electron transport 0.3245826252936309 0.1507738586671192 0.8801541082561519 1.0 1.0 38 P00403,O43676,Q9UDW1,Q9Y6M9,P03915 5 +Positive regulation of protein polyubiquitination 0.35063663075416 0.150328061707381 0.8805057945067498 1.0 1.0 5 O00571,Q13309,P61088,O75150 4 +Response to interleukin 1 0.3023072823917085 0.1495002209183489 0.8811589350588371 1.0 1.0 13 P38159,P17252 2 +Peptidyl tyrosine dephosphorylation 0.3212906225253185 0.1469637937546011 0.8831605983560515 1.0 1.0 10 Q99956,P10586 2 +Positive regulation of viral genome replication 0.2919397116644714 0.1467037062740151 0.8833658930765667 1.0 1.0 16 Q6PKG0,Q6L8Q7,P55265,O43447,O95793,Q02880,O00571,Q16513,Q9UIV1,O95292,Q96SB4,Q9P035,Q08752,P11940,P11388 15 +Immunoglobulin production 0.299990809592759 0.1465074446302927 0.8835208133677752 1.0 1.0 24 P10809,Q9UQ84,P20585,Q96FZ2 4 +Negative regulation of b cell proliferation 0.4554649265905245 0.1444721726164874 0.8851276289383554 1.0 1.0 3 Q96IZ0,P07948 2 +Regulation of transcription of nucleolar large rrna by rna polymerase i 0.320470896010468 0.1442721501186852 0.8852855691942811 1.0 1.0 10 P19338,Q9NWS0,Q12824,P51532,Q13610,P42345,Q9H8H0,O75367,P56192 9 +Positive regulation of erbb signaling pathway 0.3477420912706435 0.1438549627690443 0.8856150001820606 1.0 1.0 5 Q9NQC3 1 +Positive regulation of cell differentiation 0.2795160472783364 0.1438486516075078 0.8856199839275489 1.0 1.0 118 Q8WUJ1,Q16706,Q9UQB8,P00813,P22392,Q9Y3B8,P17252,O15031,P55209,P30536 10 +Folic acid containing compound metabolic process 0.3005930134731488 0.1434035861053113 0.8859714509458456 1.0 1.0 13 Q8IYS1,Q9NRN7,P41440 3 +Polyadenylation dependent snorna 3 end processing 0.3544251171918927 0.1428497436183335 0.8864088501726466 1.0 1.0 6 Q9NQT4,Q13868,O95453 3 +Ensheathment of neurons 0.3082883799463063 0.1427550262767063 0.8864836570251331 1.0 1.0 28 Q9NR77 1 +Aminoglycan biosynthetic process 0.3460679539734086 0.1424818105282512 0.8866994458804955 1.0 1.0 7 P06865,Q7LGA3,O94923 3 +Regulation of guanyl nucleotide exchange factor activity 0.3814636206461119 0.138485035978808 0.8898570952235083 1.0 1.0 4 Q9NWH9 1 +Skeletal muscle adaptation 0.4516880286517959 0.138202506674455 0.8900803740697705 1.0 1.0 3 P16615 1 +Regulation of skeletal muscle adaptation 0.4516880286517959 0.138202506674455 0.8900803740697705 1.0 1.0 3 P16615 1 +Lipid import into cell 0.3518298023113094 0.1366221598683103 0.8913294597040955 1.0 1.0 6 O14975 1 +Cenp a containing chromatin organization 0.6144814090019456 0.1366082900284287 0.8913404234442419 1.0 1.0 2 Q6IPU0 1 +Regulation of ryanodine sensitive calcium release channel activity 0.3437577346524086 0.1361278039548189 0.8917202477378945 1.0 1.0 7 P17252 1 +Protein maturation by protein folding 0.3514825906678588 0.135797641712405 0.8919812554327828 1.0 1.0 6 Q13162,Q8N4Q1 2 +N acetylneuraminate metabolic process 0.3792428198433478 0.1343091751645695 0.8931580982482925 1.0 1.0 4 Q8NFW8,P46926,Q9UJ70 3 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.317200784826685 0.1336856057389411 0.893651187940171 1.0 1.0 10 P08238,Q9C0C9,Q14980,Q13573,Q9BRX2,P67870,Q8N1F7,Q93062,Q14318 9 +Prolactin secretion 0.6108936725374947 0.1319992817244561 0.8949848598786314 1.0 1.0 2 P04083 1 +Regulation of heart contraction 0.3014498519161729 0.1312683173516078 0.8955630539742647 1.0 1.0 26 P00813,P17252 2 +Lung associated mesenchyme development 0.6102413568166873 0.1311741082852127 0.8956375775528826 1.0 1.0 2 P35222 1 +Convergent extension 0.6102413568166873 0.1311741082852127 0.8956375775528826 1.0 1.0 2 Q13263 1 +Positive regulation of chromatin organization 0.3243183254759519 0.1305288133571543 0.8961480593821571 1.0 1.0 9 Q9UK61,Q9Y6X9,Q8NEY8,P12270 4 +Regulation of response to endoplasmic reticulum stress 0.282392800694476 0.1304544219660539 0.8962069119131388 1.0 1.0 19 O43765,P30040,P51572,Q96HY6,P46379,O95881 6 +Somatic diversification of immune receptors 0.2933165289576204 0.1281411562317023 0.8980372665394429 1.0 1.0 23 P10809,Q9UQ84,P20585,Q96FZ2 4 +Lipid droplet formation 0.3751949362608638 0.1268818585936451 0.8990339053265293 1.0 1.0 4 Q14534,Q9Y679 2 +Regulation of synapse assembly 0.3400849395622353 0.1262290311715747 0.8995506316085695 1.0 1.0 7 Q13641,Q15375,Q96QK1,Q04637,Q96HC4,Q9H2P0 6 +Pattern specification process 0.3067572321068699 0.126120031783655 0.8996369110120273 1.0 1.0 29 P98172,P80723,P62995,P17252,O94788 5 +Regulation of muscle system process 0.313584308645578 0.1253023022143188 0.9002842296465978 1.0 1.0 33 P00813,P17252,P08133 3 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.6046966731898136 0.1243187341320041 0.901062914674148 1.0 1.0 2 P60953 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.6046966731898136 0.1243187341320041 0.901062914674148 1.0 1.0 2 P60953 1 +Negative regulation of megakaryocyte differentiation 0.6033920417481962 0.1227467841790997 0.9023076155386862 1.0 1.0 2 Q99873 1 +Organelle fusion 0.3227200881028581 0.1225622621453318 0.9024537395217628 1.0 1.0 44 Q9Y6C9,O95249,Q8TB36,Q99536,Q9P253,Q9Y4W6,O95721,P56962,Q969M3,Q8IWA4,Q9NX63,O15400,Q86Y82,Q9GZY8 14 +Regulation of histone h2b ubiquitination 0.4407830342577361 0.1210669668080984 0.9036379933468068 1.0 1.0 3 Q5VTR2,O75150 2 +Positive regulation of atp dependent activity 0.2830886454466998 0.1205869599939166 0.9040181978827384 1.0 1.0 20 Q5JTV8,P35080,P20585 3 +Transport of virus 0.3448871247928887 0.1205254742422606 0.90406690120341 1.0 1.0 6 P52292 1 +Multi multicellular organism process 0.2988985072264327 0.1197899542332609 0.9046495399981492 1.0 1.0 26 Q9UIQ6,P41440 2 +Protein heterotetramerization 0.3283051791486122 0.119122684924795 0.9051781587352364 1.0 1.0 8 Q9NSD9,Q8N684 2 +Basement membrane organization 0.3442194644023487 0.1190210071857314 0.9052587127528384 1.0 1.0 6 Q14118,P05556,P07942,Q9NPQ8,O60568 5 +Negative regulation of immune response 0.2826757104367116 0.1188588044225534 0.9053872196365752 1.0 1.0 20 P04439,P28070,P46108,P19474 4 +Maternal placenta development 0.4391517128874325 0.118626851738269 0.9055709909493674 1.0 1.0 3 P30048,P35613 2 +Activation of protein kinase c activity 0.5994781474233428 0.1181242356025057 0.905969220652155 1.0 1.0 2 Q99623 1 +Regulation of phospholipase c activity 0.5994781474233428 0.1181242356025057 0.905969220652155 1.0 1.0 2 Q99623 1 +Activation of phospholipase c activity 0.5994781474233428 0.1181242356025057 0.905969220652155 1.0 1.0 2 Q99623 1 +Response to nicotine 0.3701044386423027 0.1178795074734492 0.9061631306923396 1.0 1.0 4 O00330,P28482,P09601 3 +Smooth muscle cell migration 0.3120311088184865 0.1174499585719826 0.9065034967697836 1.0 1.0 10 O15511,P31949,P46108,Q07954 4 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.3276600657824181 0.1171964384213267 0.9067043891992266 1.0 1.0 8 Q13868 1 +Positive regulation of muscle cell differentiation 0.3357506327496617 0.1148716752646464 0.9085468363104696 1.0 1.0 7 Q9BWF3 1 +Response to salt stress 0.3422842802049121 0.1147037926537354 0.9086799076703584 1.0 1.0 6 P04637,Q9BPX6 2 +Blastocyst growth 0.3267973856209173 0.1146339704051059 0.9087352527012064 1.0 1.0 8 O75312,Q9BRT9,Q9Y3A5,O60934,Q6PD62,Q9BRX2,Q92541 7 +Regulation of peptidase activity 0.2703714150080446 0.1145301443693734 0.9088175518601468 1.0 1.0 75 Q9Y255,P10809,Q15392,Q9NR28,O14737,P16435,O95831,P51572,Q9Y3B8,Q9P0J0,Q92530,Q96F07,Q96HY6,Q07954 14 +Nephron morphogenesis 0.4361802316278773 0.1142642855636793 0.9090282930190248 1.0 1.0 3 Q12959 1 +Calcium ion export 0.3673801923292312 0.1132165671943363 0.9098588613953118 1.0 1.0 4 P62258 1 +Paraxial mesoderm development 0.4350623727099537 0.1126505123295465 0.910307636844616 1.0 1.0 3 Q96A65 1 +Protein heterooligomerization 0.3182224689040849 0.1119076631680362 0.9108966204444716 1.0 1.0 9 Q9NSD9,Q8N684 2 +Cellular response to acid chemical 0.292983576806094 0.1113196461095811 0.9113628768865408 1.0 1.0 12 Q9UQB8,Q14103,Q99729 3 +Sodium ion export across plasma membrane 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 1.0 3 P05023,P05026 2 +Positive regulation of potassium ion import across plasma membrane 0.4339314845024397 0.1110331475033144 0.9115900613313666 1.0 1.0 3 P05026,Q9H4A3 2 +Mesonephros development 0.331737869047196 0.1106322520654482 0.9119079710176116 1.0 1.0 5 P80723,Q12959 2 +Dephosphorylation 0.2471684244521564 0.1099462750147112 0.9124519828191312 1.0 1.0 82 P34913,Q9NPH0,Q969T7,P10586,Q99956,Q86XL3,Q5TFE4,Q10713,Q96JB5 9 +Secretory granule localization 0.4326264274061945 0.1091856878919262 0.9130552118456412 1.0 1.0 3 Q12756,P33176 2 +Rna destabilization 0.3172191054168572 0.1078451975483918 0.91411848948263 1.0 1.0 39 Q86VM9,Q13868,P67809,Q92945,Q969T7,O60506,Q15024,Q9HCE1 8 +Sterol metabolic process 0.3082158477607173 0.1073650395545281 0.9144993885445628 1.0 1.0 32 P34913,Q15392,Q15126,P37268,P35610,Q16850,O15118,O75477,Q8WTV0,Q14534 10 +Post chaperonin tubulin folding pathway 0.3632506527415156 0.1063538988545583 0.9153015689368468 1.0 1.0 4 O75695,Q9BTW9,Q15813 3 +Response to angiotensin 0.3294096828006326 0.1061644560306965 0.9154518715070998 1.0 1.0 5 Q6RW13,O43865 2 +Regulation of myosin light chain phosphatase activity 0.4285489720039064 0.1035443467840333 0.9175309549742634 1.0 1.0 3 O14974 1 +Synapse maturation 0.359844878804998 0.1008801602547036 0.9196455925758708 1.0 1.0 4 P07196 1 +Protein localization to ciliary membrane 0.326317833748651 0.1003751509174751 0.920046496814737 1.0 1.0 5 Q96A65,Q9UPT5 2 +Negative regulation of lipid biosynthetic process 0.3298216130388459 0.0999126598521052 0.9204136655370698 1.0 1.0 7 O75477 1 +Mrna 3 end processing by stem loop binding and cleavage 0.5825179386823081 0.0996851013362966 0.9205943290315876 1.0 1.0 2 Q9UKF6 1 +Long chain fatty acyl coa metabolic process 0.3134369591502477 0.0978635782218362 0.9220406214840036 1.0 1.0 9 Q9UKU0 1 +Rna splicing 0.3478723190610824 0.0976747670387309 0.922190552714383 1.0 1.0 226 P84103,P62312,P23246,Q8WVV9,Q9NW64,Q92804,Q9ULX6,Q14011,Q86V81,Q13595,Q12972,P31483,P35637,P98175,P55081,Q96T37,P38159,Q9Y5S9,Q8IWZ8,Q96PK6,Q08170,P31942,P52597,O43290,Q07666,P61978,P67809,O60506,P22626,Q14004,Q9Y4C8,Q92945,Q8N163,Q5BKZ1,O75525,P31943,Q9BWF3,Q9H2H8,O75494,Q92879,O43390,Q14331,Q8IY67,Q16629,P62995,P07910,P98179,Q12874,Q96QD8,Q7RTV0,O75940,P78332,Q13123,Q13242,O75475,Q15233,P19338,P55795,Q9NY27,Q07955,O75934,P51991,P52756,P17844,P54105,Q6I9Y2,Q99590,Q12849,Q15428,Q8WWY3,Q96E39,P09651,Q96PU8,Q9UHI6,P08621,Q9UKM9,O95400,Q9P013,P09012,Q92841,P49756,Q96I25,Q9Y2W1,Q9UKA9 84 +Positive regulation of transcription of nucleolar large rrna by rna polymerase i 0.3209150326797407 0.0975746272180711 0.9222700728901108 1.0 1.0 8 P19338,Q12824,P51532,Q13610,P42345,Q9H8H0,P56192 7 +Biomineralization 0.2964933261738076 0.0956529313811843 0.923796224727746 1.0 1.0 11 O75844 1 +Fc epsilon receptor signaling pathway 0.5779517286366458 0.0951534143760222 0.9241929719651168 1.0 1.0 2 P07948 1 +Regulation of intracellular estrogen receptor signaling pathway 0.2812575623535784 0.0947164991973209 0.9245400124324268 1.0 1.0 15 Q96HY6 1 +Cellular respiration 0.2598775856901082 0.0946295362946692 0.9246090885312463 1.0 1.0 99 Q5U5X0,Q13423,P48735,P00403,O75964,O43676,P00846,P22695,Q9UDW1,Q9Y6M9,O75874,P03915 12 +Regulation of lipid biosynthetic process 0.2901543711315986 0.0925289267466397 0.9262778095774076 1.0 1.0 25 Q9UHI6,P11802,O75477,Q8WTV0,O75874,P30536 6 +Positive regulation of double strand break repair 0.2820581867375898 0.0923336734174902 0.9264329351155238 1.0 1.0 22 Q7Z4V5,P35637 2 +Zinc ion homeostasis 0.3314661046223858 0.0917672258935025 0.9268829841019944 1.0 1.0 6 Q15043,Q8TAD4 2 +Myoblast differentiation 0.3188338221413583 0.0917136052070226 0.9269255875602942 1.0 1.0 8 Q15149,Q92841,P05556,P17844 4 +Regulation of cellular ph 0.2758073818770629 0.0910233503092406 0.9274740372075844 1.0 1.0 20 Q8N511,Q15904,Q93050 3 +Regulation of ph 0.2758073818770629 0.0910233503092406 0.9274740372075844 1.0 1.0 20 Q8N511,Q15904,Q93050 3 +Fatty acid beta oxidation using acyl coa dehydrogenase 0.3108381674980434 0.0904522610313386 0.9279278285572724 1.0 1.0 9 Q16134,P49748 2 +Nephron epithelium development 0.3183489837027193 0.0903614709852375 0.9279999730968962 1.0 1.0 8 P35222,P35610,P80723,Q12959 4 +Poly a plus mrna export from nucleus 0.3107617782662726 0.0902367255024259 0.9280991006273156 1.0 1.0 9 Q8N1F7,Q86U42 2 +Positive regulation of viral life cycle 0.324933196602068 0.0880874535678065 0.929807168217064 1.0 1.0 7 P52292,P19474 2 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3508485639686698 0.087226558298579 0.9304914293375496 1.0 1.0 4 P11940,Q9UIV1,Q9H2U1 3 +Postsynaptic membrane organization 0.3244157381807016 0.0868628365341964 0.9307805399751712 1.0 1.0 7 P49354 1 +Epithelial cell proliferation involved in lung morphogenesis 0.4153344208809061 0.0866088980203448 0.930982392883511 1.0 1.0 3 P60953,Q13247 2 +Protein o linked glycosylation 0.2786748675277957 0.0860538281717883 0.9314236271899932 1.0 1.0 15 Q10472,Q8NAT1,O60502 3 +Endosome to lysosome transport 0.2809625098651713 0.0853871598048012 0.9319536008720302 1.0 1.0 14 Q9P253,Q99523,Q99816,P20645,Q9H267 5 +Membrane depolarization 0.2829407927415002 0.0853687451224037 0.9319682402095006 1.0 1.0 13 P30536 1 +Regulation of muscle hypertrophy 0.2842368272744792 0.0848326000970449 0.9323944758190325 1.0 1.0 12 P17252 1 +Atp transport 0.3278976395101254 0.0846500273860155 0.9325396256623651 1.0 1.0 6 P12235,O43808,Q08722 3 +Positive regulation of transporter activity 0.2707842085503275 0.0837247304587265 0.9332752941133476 1.0 1.0 19 P08183 1 +Regulation of mrna 3 end processing 0.2673031420799798 0.0828760884733318 0.9339500672537322 1.0 1.0 18 O43865,P09012 2 +Apoptotic chromosome condensation 0.5639269406392541 0.0823415534938162 0.934375111681182 1.0 1.0 2 Q9UKV3 1 +Negative regulation of response to endoplasmic reticulum stress 0.2915311035696974 0.0813036537208575 0.9352004683632158 1.0 1.0 11 O43765,Q96HY6,O95881 3 +Histone h3 acetylation 0.2828729490662123 0.0808931940360068 0.9355268926007254 1.0 1.0 12 Q03164,Q14012 2 +Sensory system development 0.3069877973292955 0.0802329056860673 0.9360520195598518 1.0 1.0 35 P08670,P54802,O94788,Q16706 4 +Negative regulation of telomere maintenance via telomere lengthening 0.298467443363383 0.0778576373074868 0.9379412976040176 1.0 1.0 10 P07910 1 +Protein localization to presynapse 0.3440708649262192 0.0777047427560857 0.9380629213423316 1.0 1.0 4 Q14168 1 +Axo dendritic protein transport 0.3440708649262192 0.0777047427560857 0.9380629213423316 1.0 1.0 4 Q14168 1 +Basement membrane assembly 0.3439947780678851 0.0776015435517436 0.9381450145092924 1.0 1.0 4 Q14118,O60568,P07942 3 +Mirna metabolic process 0.3202900707269462 0.0772859537514673 0.9383960647662624 1.0 1.0 7 Q92841,Q92945 2 +Regulation of mitochondrial rna catabolic process 0.3121123081945848 0.0758827120265606 0.9395124110026492 1.0 1.0 5 Q8IYB8,P42704,Q9GZT3,Q12849 4 +Myeloid cell apoptotic process 0.341510084132787 0.0742762132851926 0.9407906037878024 1.0 1.0 4 P04083 1 +Regulation of myeloid cell apoptotic process 0.341510084132787 0.0742762132851926 0.9407906037878024 1.0 1.0 4 P04083 1 +Positive regulation of protein localization to cell cortex 0.4032626427406183 0.0728989938181447 0.9418864946318002 1.0 1.0 3 Q14980,P11171 2 +Tissue migration 0.3129720915887454 0.072671692142144 0.9420673753677152 1.0 1.0 51 P42785,P17252,Q8WTV0,Q9NQC3 4 +Pseudopodium organization 0.551532941943884 0.0723567930425042 0.9423179687800296 1.0 1.0 2 P60953 1 +Positive regulation of pseudopodium assembly 0.551532941943884 0.0723567930425042 0.9423179687800296 1.0 1.0 2 P60953 1 +L aspartate transmembrane transport 0.4026101141924965 0.0722046636191109 0.9424390338322512 1.0 1.0 3 Q15758,Q9UJS0 2 +Glutamate biosynthetic process 0.402610114192494 0.0722046636191084 0.9424390338322532 1.0 1.0 3 O94925,P00367 2 +Single stranded viral rna replication via double stranded dna intermediate 0.317869977131661 0.0718233797259282 0.9427424665371592 1.0 1.0 7 Q02880,Q12824,Q9UK61,Q13263,Q9Y6X9,P11388 6 +Regulation of phosphatidylcholine biosynthetic process 0.4019575856443669 0.0715150569100534 0.9429878415592374 1.0 1.0 3 Q8NF37,P17655 2 +Regulation of nucleocytoplasmic transport 0.3129989051135598 0.0704326331392956 0.9438493182449936 1.0 1.0 50 O00459,Q9BWF3,Q9BVL2,Q9ULX6,Q07666,P50402,Q7Z3B4,Q9BVS4,O14974,P12270,Q14978,Q9NW64,Q9Y3B8,Q9NPF5,P17252,Q14012,Q08J23 17 +Response to temperature stimulus 0.3133908818371906 0.0700743167860483 0.9441345086745848 1.0 1.0 46 P00403,P10809,Q14011 3 +G protein coupled receptor signaling pathway 0.3125114175090088 0.0681103362165486 0.9456978023550612 1.0 1.0 44 P00813,Q9UBI6,P07602,Q15043,O43865,Q99523,P17252,O43813,P42892,P11717 10 +Rna surveillance 0.2944390044206542 0.0669585768067108 0.946614680074376 1.0 1.0 10 Q13868 1 +Adherens junction assembly 0.3062357166177032 0.0667548566575213 0.9467768623676456 1.0 1.0 5 P35222,P18206,Q9BX67,Q9BTW9 4 +Intraciliary transport involved in cilium assembly 0.5427266797129635 0.0659868776923943 0.9473882727682854 1.0 1.0 2 A0AVF1 1 +Response to alcohol 0.3023156770156151 0.0658486926866034 0.9474982891718908 1.0 1.0 34 O43823,Q15126,P11802,O95831,Q9NPF5,P16278,P07196,P30536 8 +Inner ear receptor cell stereocilium organization 0.3964110929853128 0.065842503307707 0.9475032168877582 1.0 1.0 3 Q9BW83,Q14160 2 +Negative regulation of cell adhesion mediated by integrin 0.3963314357750508 0.0657634807169939 0.9475661314342154 1.0 1.0 3 Q9BX67 1 +Regulation of endothelial cell differentiation 0.3144221478200003 0.0642400996187303 0.9487790484387726 1.0 1.0 7 P35222,Q13464,O14974 3 +Dna dealkylation involved in dna repair 0.3944535073409393 0.0639203691128243 0.9490336332372382 1.0 1.0 3 Q9C0B1,P29372 2 +Centromeric sister chromatid cohesion 0.3039496742279479 0.0633609147549039 0.9494791101919756 1.0 1.0 5 P41227 1 +Regulation of protein targeting 0.2743565031220679 0.0624266091794972 0.950223105219764 1.0 1.0 22 P55786,Q9UII2 2 +Embryonic cleavage 0.3032974208292593 0.0624085604534153 0.9502374779945184 1.0 1.0 5 P11388,Q9NY61,P11387,Q13618 4 +Negative regulation of dna biosynthetic process 0.2756896388868071 0.0610060859047629 0.9513543622345024 1.0 1.0 12 P07910 1 +Positive regulation of ire1 mediated unfolded protein response 0.532615786040425 0.0593774261183549 0.9526514926775482 1.0 1.0 2 P18031 1 +Regulation of perk mediated unfolded protein response 0.532615786040425 0.0593774261183549 0.9526514926775482 1.0 1.0 2 P18031 1 +Positive regulation of endoplasmic reticulum unfolded protein response 0.532615786040425 0.0593774261183549 0.9526514926775482 1.0 1.0 2 P18031 1 +Negative regulation of actin filament bundle assembly 0.3065359477124203 0.05898741018738 0.9529621358657404 1.0 1.0 8 P16949,P07737,Q9Y624,P63167,Q07157,Q9NWH9,Q7Z460 7 +Histone monoubiquitination 0.2913669064748215 0.058916382466162 0.9530187093966832 1.0 1.0 10 P63208,Q99496,O75150,Q8N7H5,Q6PD62,Q96T88,Q5VTR2,Q13620,Q6P1J9 9 +Protein transport along microtubule 0.2997061704211637 0.0572915276091286 0.9543129692578298 1.0 1.0 5 O95817,P33176,Q14168,P04792 4 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.2822298005653479 0.0561418076750533 0.9552288387313576 1.0 1.0 11 Q96K76,P61978,Q8N163,P14174 4 +Mitochondrial rna catabolic process 0.3122142390594387 0.0560198614922212 0.9553259848225082 1.0 1.0 6 Q6L8Q7,Q8IYB8,Q9GZT3,P42704,Q12849 5 +Defense response to fungus 0.2987249214463542 0.0559304595230335 0.9553972056108126 1.0 1.0 5 P81605 1 +Positive regulation of cell adhesion 0.2975929021987345 0.0546050334056422 0.9564531286660268 1.0 1.0 62 P10809,P00813,P46108,P41440,P98172,P30825,P17252,Q08722 8 +Regulation of dna damage checkpoint 0.3102547354670143 0.0527453968376132 0.957934767898586 1.0 1.0 6 Q96FV9,P15927,Q8N163,Q13838,Q13769 5 +Negative regulation of protein catabolic process 0.3058175744002319 0.052499299324993 0.9581308536242084 1.0 1.0 39 P10619,O43765,P08621,Q16850,Q96KB5,Q92530,Q96HY6,Q9UL15,P46379,Q96JB5 10 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.3797716150081546 0.0507917881592765 0.9594914345321768 1.0 1.0 3 Q8WUM4,O75351 2 +Circadian rhythm 0.3078808417929791 0.0503099786798703 0.9598753720044736 1.0 1.0 42 Q15233,Q9BWF3,Q14103,Q03164,P54802,Q9BQG2,Q9Y2W1,P23246,P43490,Q8WXF1 10 +Regulation of ribosome biogenesis 0.5163078930202021 0.0501989899866216 0.959963816414888 1.0 1.0 2 Q5T3I0 1 +Ectoderm development 0.3208224543080988 0.0498839212395194 0.9602148903428234 1.0 1.0 4 P35222,Q8N1B4,P13693 3 +Snorna localization 0.3204960835509196 0.0495449410226639 0.96048502339638 1.0 1.0 4 Q8WWY3,P22087,Q9Y2X3 3 +Establishment of golgi localization 0.3781402936378399 0.049469202929909 0.9605453796408256 1.0 1.0 3 P63104,P60953 2 +Positive regulation of mitochondrion organization 0.2707142493823311 0.0490757160621329 0.960858955858066 1.0 1.0 22 P21796,Q9UII2 2 +Regulation of mitochondrion organization 0.308210202069148 0.0489560190454683 0.9609543456011604 1.0 1.0 43 Q9Y6C9,Q9P275,Q9Y255,Q99536,O14737,P02545,Q8IXI1,Q9H3K2,Q9UII2,P21796,P30536 11 +Embryonic cranial skeleton morphogenesis 0.3771615008156569 0.0486883273329846 0.9611676782830212 1.0 1.0 3 P38919,P11586 2 +Positive regulation of striated muscle contraction 0.5114155251141349 0.0477788815179522 0.9618924674382644 1.0 1.0 2 P05023 1 +Regulation of transcription by glucose 0.5101108936725212 0.0471581638350492 0.9623871708242212 1.0 1.0 2 Q96EB6 1 +Protein kinase a signaling 0.3016635946908435 0.046939111102713 0.9625617562810952 1.0 1.0 8 O00170,P17252 2 +Meiotic sister chromatid cohesion centromeric 0.509458577951712 0.0468516306411739 0.9626314788824116 1.0 1.0 2 P30153 1 +Meiosis ii cell cycle process 0.509458577951712 0.0468516306411739 0.9626314788824116 1.0 1.0 2 P30153 1 +Estrous cycle 0.3745513866231617 0.0466520087664171 0.9627905801225812 1.0 1.0 3 P04083,Q9H2P0 2 +Negative regulation of epithelial cell differentiation 0.3729200652528533 0.0454129530971878 0.9637781565614858 1.0 1.0 3 P35222,Q13247 2 +Relaxation of muscle 0.3162532637075815 0.0452631644264646 0.9638975478592802 1.0 1.0 4 P05023,P30626,P05026 3 +Inflammatory response 0.2856183623427161 0.0435139526139308 0.965291842483532 1.0 1.0 67 P28070,P00813,P42785 3 +Centrosome duplication 0.2646495564426739 0.0427658337470328 0.9658881997794276 1.0 1.0 15 Q96PK6,P41208 2 +Dendritic spine maintenance 0.3690048939641114 0.0425430760106051 0.9660657731255607 1.0 1.0 3 Q14247,Q13614 2 +Endothelial cell chemotaxis 0.3133159268929573 0.0424331192007071 0.9661534268128692 1.0 1.0 4 Q9NWH9,Q9BR76,P04792 3 +Cellular lipid metabolic process 0.3216663198354238 0.0419066520795214 0.9665731134656116 1.0 1.0 191 P34913,Q9NPH0,Q15126,P07099,Q68D91,Q9BWD1,Q8NBX0,O14975,Q96PU8,P33121,O75477,O94788,Q6NUM9,Q15067,Q9UKU0,O75844,P37268,P35610,O15254,O15121,Q8N4Q0,Q9HB40,Q8WTV0,Q13011,Q99805,O75874,Q8NCC3,P51648,Q10713,P28288,Q96G23,P23786,Q06136,P16435,Q96N66,Q9Y394,P48651,P42126,Q9BY49,P07602,Q2TAA5,Q16836,Q8N8N7,Q16134,Q8NHP8 45 +Metal ion export 0.2841750770953137 0.0410087572254522 0.9672889144801072 1.0 1.0 10 P62258,P35670,Q12959 3 +Maintenance of synapse structure 0.311684073107054 0.0409076105534567 0.9673695501835282 1.0 1.0 4 Q12959,P56545,Q14203 3 +Cardiolipin acyl chain remodeling 0.4928245270710869 0.0398562964473723 0.9682076937787972 1.0 1.0 2 Q6UWP7 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.2680953082162004 0.039795775859149 0.968255943941458 1.0 1.0 22 Q9Y3B8 1 +Lung epithelium development 0.2859941234084303 0.039686940246399 0.9683427136484551 1.0 1.0 5 Q02750,Q13247,P60953,P09960 4 +Rna catabolic process 0.2712811768359882 0.0392601283048601 0.9686829950946448 1.0 1.0 120 Q86VM9,P62312,Q13868,Q15717,Q969T7,Q15024,Q08J23,Q13151,P67809,Q99729,P17252,O60506,Q92804,Q9BQ61,Q14011,Q92945,Q9HBH5,Q9HCE1,P35637,Q9Y2W1,P98175,P07910,P08670 23 +Dendrite self avoidance 0.4898891063274497 0.0387770625494807 0.969068132510976 1.0 1.0 2 P35613 1 +Spliceosomal conformational changes to generate catalytic conformation 0.4882583170254182 0.0381964091386602 0.9695310839006764 1.0 1.0 2 O75643 1 +Bone resorption 0.2979365464050911 0.0380794451040279 0.969624339852898 1.0 1.0 8 P17252 1 +Negative regulation of smooth muscle cell migration 0.2846008143061348 0.0380656194417355 0.9696353631432606 1.0 1.0 5 Q07954 1 +Regulation of endothelial cell development 0.3006710246861605 0.0376884587804373 0.9699360780193642 1.0 1.0 6 O14974 1 +Heart formation 0.4856490541421835 0.0372948713434681 0.9702498947248062 1.0 1.0 2 P35222 1 +Lung cell differentiation 0.3607546908645151 0.0369615629412494 0.9705156531139828 1.0 1.0 3 P09960 1 +G1 to g0 transition 0.3001306335728243 0.0368864668004834 0.9705755303335584 1.0 1.0 6 Q9NNW5,Q9BQG0,O43175,P04637,O43159 5 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.2835645996233022 0.0368794032233066 0.9705811624206212 1.0 1.0 5 O14777,P12270 2 +Membrane depolarization during action potential 0.307114882506532 0.0368107819551711 0.9706358771191248 1.0 1.0 4 Q14BN4,Q9HD47,Q04917 3 +Response to l phenylalanine derivative 0.4830397912589565 0.0364264817237988 0.9709422988255384 1.0 1.0 2 P48507 1 +Response to thyroxine 0.4830397912589565 0.0364264817237988 0.9709422988255384 1.0 1.0 2 P48507 1 +Labyrinthine layer blood vessel development 0.4817351598173329 0.0360044654418748 0.9712787983566752 1.0 1.0 2 Q15738 1 +Embryonic placenta morphogenesis 0.4791258969340948 0.0351842875007619 0.9719327912321428 1.0 1.0 2 Q13263 1 +Histone h4 k20 methylation 0.3568060719168879 0.0345057371267296 0.9724738675085955 1.0 1.0 3 O96028 1 +Membrane organization 0.3385234622066363 0.033998588503807 0.9728782762626031 1.0 1.0 220 Q5JTV8,O75431,Q8NHH9,Q5HYI7,P56962,Q15070,P49354,O14964,Q9UII2,Q9P0J0,Q9NX63,Q9H3K2,Q7Z3C6,Q13505,P62072,Q3ZCQ8,Q9NS69,Q9Y255,Q9P2W9,O75844,O43765,O15121,Q14696,Q8N6H7,P08183,Q00765,P17252,P52789,Q7L5D6,P05771,P53350,Q9NQC3,P30536,Q9Y276,Q15392,Q9ULX6,P50402,Q9H6H4,O14737,P49069,Q9Y584,P02545,P45880,P08133,Q86XL3,Q8N1F7,P46379,Q9UQB8,Q9HD42,O95249,Q9BTV4,P41440,Q15629,Q92734,Q9Y4W6,O15118,Q969M3,P20700,Q96GD4,Q8IWA4,Q86Y82,O95721 62 +Epidermis morphogenesis 0.4722765818656051 0.0331774205374834 0.9735331040088872 1.0 1.0 2 P35222 1 +Nucleoside phosphate biosynthetic process 0.248194615590212 0.0324125606888426 0.9741430457705668 1.0 1.0 92 P00813,P00403,O75964,P22392,P00846,P43490,Q9UMR5 7 +Mirna loading onto risc involved in gene silencing by mirna 0.3520391517128864 0.0317192620387687 0.974695933729372 1.0 1.0 3 P55265,O75569 2 +Pre mirna processing 0.3520391517128864 0.0317192620387687 0.974695933729372 1.0 1.0 3 P55265,O75569 2 +Production of sirna involved in rna interference 0.3520391517128864 0.0317192620387687 0.974695933729372 1.0 1.0 3 O75569,Q15631 2 +Negative regulation of activated t cell proliferation 0.4634703196346951 0.0308894075503424 0.975357737443924 1.0 1.0 2 Q14160 1 +Ganglion development 0.4631441617742845 0.0308106318144877 0.9754205614846332 1.0 1.0 2 P35222 1 +Dorsal root ganglion development 0.4631441617742845 0.0308106318144877 0.9754205614846332 1.0 1.0 2 P35222 1 +Dtmp metabolic process 0.4602087410306446 0.0301199920688036 0.975971356598356 1.0 1.0 2 P04818 1 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.4602087410306446 0.0301199920688036 0.975971356598356 1.0 1.0 2 P04818 1 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.4602087410306446 0.0301199920688036 0.975971356598356 1.0 1.0 2 P04818 1 +Negative regulation of guanyl nucleotide exchange factor activity 0.3487765089722627 0.0299210451496062 0.9761300217602062 1.0 1.0 3 P16949,Q9NWH9 2 +Neurotransmitter receptor localization to postsynaptic specialization membrane 0.3486580130537434 0.0298573650948242 0.9761808084021784 1.0 1.0 3 Q12959 1 +Positive regulation of rho protein signal transduction 0.4579256360078195 0.0296051833155068 0.976381931439012 1.0 1.0 2 Q9Y624 1 +Sphingolipid mediated signaling pathway 0.4579256360078029 0.0296051833155032 0.976381931439015 1.0 1.0 2 P15311 1 +Protein dna complex disassembly 0.2608578947673248 0.0279493151697929 0.9777025759704324 1.0 1.0 14 Q969G3 1 +Regulation of extracellular matrix disassembly 0.3438825448613338 0.0273838901760766 0.9781535472082574 1.0 1.0 3 Q16658,Q07954 2 +Peptide antigen assembly with mhc protein complex 0.4425962165688057 0.026616616009458 0.9787655202956672 1.0 1.0 2 P30101 1 +Genomic imprinting 0.440639269406384 0.0262892549700755 0.9790266252425388 1.0 1.0 2 Q13263 1 +Regulation of genetic imprinting 0.440639269406384 0.0262892549700755 0.9790266252425388 1.0 1.0 2 Q13263 1 +Pteridine containing compound metabolic process 0.2537764916383294 0.0255960914557859 0.9795795036165944 1.0 1.0 17 Q8IYS1,Q9NRN7,P41440 3 +Regulation of axon guidance 0.431180691454658 0.0248610964761522 0.9801657581500144 1.0 1.0 2 Q9BVA1 1 +Smooth muscle cell chemotaxis 0.4311806914546449 0.0248610964761506 0.9801657581500156 1.0 1.0 2 Q9BR76 1 +Regulation of smooth muscle cell chemotaxis 0.4311806914546449 0.0248610964761506 0.9801657581500156 1.0 1.0 2 Q9BR76 1 +Regulation by virus of viral protein levels in host cell 0.290796344647526 0.0241829209102184 0.9807067012863973 1.0 1.0 4 Q9P035,P42224,O95793 3 +T cell proliferation 0.2694731732294831 0.0241587501669102 0.980725981116562 1.0 1.0 24 P04439,P98172,Q92542,Q12959,Q96IZ0,P30825,P49366,P04083 8 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.291593877517893 0.0237169353937844 0.9810783973146217 1.0 1.0 8 P30040 1 +Somatic stem cell population maintenance 0.4220482713633293 0.0237030512183884 0.9810894721704304 1.0 1.0 2 Q15906 1 +Ameboidal type cell migration 0.2753288921206312 0.0233384298343795 0.981380317479049 1.0 1.0 70 P57105,P42785,Q8WTV0,P17252,P08133,Q9NQC3 6 +Negative regulation of adenylate cyclase activity 0.4171559034572648 0.0231624824603671 0.9815206652321244 1.0 1.0 2 P04899 1 +Negative regulation of lyase activity 0.4171559034572648 0.0231624824603671 0.9815206652321244 1.0 1.0 2 P04899 1 +Negative regulation of myeloid leukocyte mediated immunity 0.4168297455968611 0.0231282877511882 0.9815479413556292 1.0 1.0 2 P09601 1 +Negative regulation of leukocyte degranulation 0.4168297455968611 0.0231282877511882 0.9815479413556292 1.0 1.0 2 P09601 1 +Spermine metabolic process 0.4161774298760461 0.0230605692279452 0.9816019585127777 1.0 1.0 2 Q96QD8 1 +Deadenylation dependent decapping of nuclear transcribed mrna 0.4103065883887711 0.0224899711732801 0.9820571118225824 1.0 1.0 2 Q96C86 1 +Lymphocyte anergy 0.4015003261578459 0.0217551662347113 0.9826432578752368 1.0 1.0 2 Q96J02 1 +T cell tolerance induction 0.4015003261578459 0.0217551662347113 0.9826432578752368 1.0 1.0 2 Q96J02 1 +Auditory receptor cell morphogenesis 0.3962818003913811 0.0213812429094517 0.9829415361359276 1.0 1.0 2 Q14160 1 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.3842139595564188 0.0206676457702692 0.9835107784396276 1.0 1.0 2 Q9NVJ2 1 +Positive regulation of blood pressure 0.3747553816046897 0.0202339218907721 0.9838567676641274 1.0 1.0 2 Q9H4A3 1 +Cell differentiation involved in metanephros development 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Renal vesicle development 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Metanephric nephron development 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Regulation of epithelial cell differentiation involved in kidney development 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Metanephric renal vesicle morphogenesis 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Nephron tubule epithelial cell differentiation 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Metanephric nephron morphogenesis 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.3727984344422653 0.020156035449267 0.9839188993821808 1.0 1.0 2 P35222 1 +Free ubiquitin chain polymerization 0.371819960861049 0.0201184950861149 0.9839488461858734 1.0 1.0 2 Q16763 1 +Fungiform papilla morphogenesis 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Fungiform papilla development 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Hair follicle placode formation 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Tongue morphogenesis 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Tongue development 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Ectodermal placode development 0.3698630136986255 0.0200461294665186 0.9840065739545124 1.0 1.0 2 P35222 1 +Morphogenesis of an endothelium 0.3450750163078884 0.0193896018850248 0.9845303053443566 1.0 1.0 2 P35222 1 +Regulation of extracellular matrix assembly 0.3437703848662701 0.0193659309200522 0.984549188496223 1.0 1.0 2 Q14118 1 +Positive regulation of extracellular matrix assembly 0.3437703848662701 0.0193659309200522 0.984549188496223 1.0 1.0 2 Q14118 1 +Positive regulation of basement membrane assembly involved in embryonic body morphogenesis 0.3437703848662701 0.0193659309200522 0.984549188496223 1.0 1.0 2 Q14118 1 +Synaptic vesicle uncoating 0.337899543378992 0.0192698503995319 0.984625835357204 1.0 1.0 2 O14976 1 +Oocyte construction 0.3356164383561552 0.0192367594465126 0.9846522332245562 1.0 1.0 2 Q9BQA1 1 +Digestive tract morphogenesis 0.3206131767775557 0.0190685138893647 0.9847864491378372 1.0 1.0 2 P35222 1 +Foregut morphogenesis 0.3206131767775557 0.0190685138893647 0.9847864491378372 1.0 1.0 2 P35222 1 +Neural plate development 0.3206131767775557 0.0190685138893647 0.9847864491378372 1.0 1.0 2 P35222 1 +Positive regulation of anoikis 0.3101761252446162 0.0189911266962362 0.984848184005262 1.0 1.0 2 Q9Y3E5 1 +Axon ensheathment in central nervous system 0.3030006523157204 0.0189518007744076 0.984879555904987 1.0 1.0 2 Q92542 1 +Tyrosine metabolic process 0.2778864970645789 0.0188729919337757 0.984942425017688 1.0 1.0 2 P61457 1 +Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest 0.27364644487932 0.0188657692054742 0.9849481868952268 1.0 1.0 2 P04637 1 +Tetrahydrofolate interconversion 0.2860516446612342 0.0177229358925698 0.985859883323992 1.0 1.0 6 P13995,P34897 2 +Negative regulation of dendritic spine development 0.2803524804177594 0.0176241313481682 0.9859387056332902 1.0 1.0 4 Q92769,Q96EV8,Q8N5V2 3 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.2534581279650051 0.0176108016966792 0.9859493395060412 1.0 1.0 16 P14174,P61978,Q9BVC6,Q96RU2,P04637,P46379 6 +Regulation of mitochondrial membrane potential 0.2501347020615158 0.0150920613708951 0.9879587343503564 1.0 1.0 17 Q9Y255,Q9UII2,P30536 3 +Pathway restricted smad protein phosphorylation 0.2733438253674113 0.0138282761164875 0.9889669836097326 1.0 1.0 4 Q07954 1 +Response to chemokine 0.2731492894585201 0.0137294717498528 0.98904581060508 1.0 1.0 4 Q96T37 1 +Neurotransmitter metabolic process 0.3023207431639213 0.0124681212353662 0.9900521363040292 1.0 1.0 3 P21964 1 +Regulation of vesicle fusion 0.3017944535073447 0.0123431864204948 0.99015181219349 1.0 1.0 3 P07355,P04083 2 +Positive regulation of striated muscle cell apoptotic process 0.301517444870007 0.0122779623099246 0.9902038495610096 1.0 1.0 3 P17655 1 +Tube formation 0.2532433480220652 0.0121950388120558 0.9902700079864676 1.0 1.0 20 P17252 1 +Negative regulation of dendritic spine morphogenesis 0.3003268330011591 0.0120017801813587 0.990424194779213 1.0 1.0 3 Q96EV8 1 +Response to lead ion 0.3001631321370324 0.0119643306062067 0.9904540730717906 1.0 1.0 3 P62136,P36551 2 +Monoamine transport 0.2922843051092446 0.0103051596408344 0.9917778177538032 1.0 1.0 3 Q96EV8 1 +Dopamine transport 0.2922843051092446 0.0103051596408344 0.9917778177538032 1.0 1.0 3 Q96EV8 1 +O glycan processing 0.2547012946466189 0.0101604528483051 0.991893271024572 1.0 1.0 5 Q10472 1 +Mucopolysaccharide metabolic process 0.2851980097844809 0.0101486184059579 0.9919027130565884 1.0 1.0 8 P15586,O94923,P16278 3 +Regulation of centrosome cycle 0.2623722131922289 0.0101090952502036 0.9919342463547558 1.0 1.0 11 Q96PK6 1 +Humoral immune response 0.2616659385355724 0.0086647297982774 0.993086632376976 1.0 1.0 11 Q9UQ84 1 +Amyloid beta clearance by transcytosis 0.252568453655539 0.0086360962601265 0.9931094777802144 1.0 1.0 5 Q07954 1 +Mismatch repair 0.2693708550779741 0.008226053151476 0.9934366332157734 1.0 1.0 10 Q9UQ84 1 +Regulation of lymphocyte activation 0.2996187805446536 0.0077262979576593 0.9938353674811372 1.0 1.0 54 P04439,O43290,Q9Y255,P10809,P00813,Q96FZ2,O96028,O96005,P98172,Q12959,P30825,P49366,Q08722,P04083 14 +Dna damage response signal transduction resulting in transcription 0.2737357259380125 0.0073706672713749 0.9941191116296482 1.0 1.0 3 Q9UNS2,P04637 2 +Ribosomal large subunit export from nucleus 0.2507345739471183 0.0073706615038463 0.9941191162313452 1.0 1.0 5 P06748,P62826,Q99567,Q15050 4 +Positive regulation of fatty acid metabolic process 0.2698205546492699 0.0068990303134082 0.99449541389507 1.0 1.0 3 P50416,P04083 2 +Negative regulation of lymphocyte differentiation 0.2491021873979824 0.006278850407307 0.9949902351179044 1.0 1.0 5 P32119,Q13951,O15347,P04083 4 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.2623350481053156 0.0061171312771647 0.9951192658365036 1.0 1.0 3 P04083 1 +Negative regulation of alpha beta t cell differentiation 0.2623350481053156 0.0061171312771647 0.9951192658365036 1.0 1.0 3 P04083 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.2623350481053156 0.0061171312771647 0.9951192658365036 1.0 1.0 3 P04083 1 +T helper 1 type immune response 0.2489396411093024 0.0050532863019208 0.995968078038048 1.0 1.0 3 P42345,P04083 2 +T helper 1 cell differentiation 0.2489396411093024 0.0050532863019208 0.995968078038048 1.0 1.0 3 P42345,P04083 2 +Negative regulation of hydrogen peroxide mediated programmed cell death 0.2446982055464968 0.0047918291620032 0.996176688125215 1.0 1.0 3 Q12931,Q9NWH9 2 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.2500000000000076 0.0042387472158651 0.9966179791667672 1.0 1.0 4 P14174,Q96EB6,O75832 3 +Negative regulation of t cell differentiation 0.2490208877284689 0.00392720164212 0.996866554497071 1.0 1.0 4 Q13951,P32119,P04083 3 +Rho protein signal transduction 0.2538207831140381 0.0037737720064579 0.9969889727269104 1.0 1.0 21 Q14344,P05556,P57105,Q07960,P41440,Q13464,P63167,Q9NWH9,Q9P035 9 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.2689648677367003 0.00362273255675 0.9971094839476669 1.0 1.0 26 O43765,Q96KB5,Q92530,Q96HY6,Q9UL15,P46379 6 +Regulation of mrna polyadenylation 0.2509905402920744 0.0034409037717145 0.9972545614229242 1.0 1.0 13 P18615,Q8N684,P09012,O75150 4 +Physiological cardiac muscle hypertrophy 0.2467362924282046 0.0032254742180976 0.997426448382516 1.0 1.0 4 P11413,O94826,Q96HC4 3 +Protein targeting to lysosome 0.2589090036356763 0.0031522793945227 0.9974848491052266 1.0 1.0 11 Q99523,O14964,Q14108,Q7Z3T8 4 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.2850149487379496 0.0026025511732326 0.9979234669443326 1.0 1.0 33 P10809,P00813 2 +Regulation of viral transcription 0.2362924281984415 0.0004384584394779 0.999650160791796 1.0 1.0 4 Q08211,P19474,Q96T23 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..17b31020ed1372f9e1da114806e7767095c44aba --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Antral ovarian follicle growth", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp catabolic process", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cholesterol", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary vasculature development", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell migration", "Hematopoietic stem cell migration to bone marrow", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Iodide transport", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte migration involved in inflammatory response", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle atrophy", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet dense granule organization", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cell adhesion mediated by integrin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of regulatory t cell differentiation", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein c linked glycosylation", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinolinate metabolic process", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of voltage gated sodium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to inactivity", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle inactivity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to stimulus involved in regulation of muscle adaptation", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C3orf58", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPI", "CENPP", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG4", "COG6", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM161A", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41B", "TMEM43", "TMEM65", "TMEM70", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSPO", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFC3H1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", 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sha256:455307e7b35b0d14abe4212708ced2dbda88601e7fd23b43257a8877c235759f +size 91155 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f2b3c59898944202d1ab540055a5d7ca5dd2bb95 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Outer membrane 21 83 3.168595635759813 0.0015317734466184 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 0.0001377124033726 0.0016900813978939 5.809670081265907e-05 0.0004346855761492 6.363963400527423e-05 +Intrinsic component of mitochondrial membrane 24 50 2.834741192570178 0.0045862823365241 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 0.0005243176497467 3.588738345123558e-05 0.0001066840361729 0.0006100016710547 0.0014287535135353 +Intrinsic component of organelle membrane 47 131 2.794336806677556 0.0052006282279211 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 0.0134090115869936 0.0030261455975404 0.0083073369666447 0.0025747616607714 0.0007136186545931 +Intrinsic component of mitochondrial inner membrane 18 35 2.7434319233654625 0.0060800653604999 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 5.968853628361053e-05 3.745017516666605e-06 7.631546446868991e-06 0.0001800616428063 0.0005879318152671 +Outer mitochondrial membrane protein complex 5 15 2.7389143994066587 0.0061642420774394 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0121065438957565 0.0001122733832082 0.0008717411361388 9.045491853019026e-05 0.0002747300414667 +Intrinsic component of plasma membrane 27 87 2.6649250390170485 0.0077005485654633 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.5596633879737833 0.6637318598957465 0.6629010367437369 0.2379078345463602 0.3343360929921224 +Inner mitochondrial membrane protein complex 21 78 2.649193021953772 0.0080684234933823 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 1.4504851231184051e-05 1.0297682918208674e-08 4.84693180956166e-08 1.6605644400980115e-08 3.5881229134361527e-09 +Cell surface 28 77 2.5133265954556467 0.011959855770296 21.233009708737864 77.5995145631068 0.4772545566224628 0.498248600191797 7.455308766626032 8.832436895439663 1.3320096182828691 0.3812427248674431 0.0168348427475577 0.192349493051136 0.0318138997068963 0.2304907134870462 0.3612774328964791 +Tim23 mitochondrial import inner membrane translocase complex 2 7 2.4220805243319945 0.0154319305845571 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0036811661553703 1.6752670706047648e-05 0.0001343549216781 0.001983278822638 0.0140126286640228 +External side of plasma membrane 4 22 2.393085772470972 0.0167073348304798 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 0.0122148429947128 0.0919108957066336 0.0189133156354044 0.1131258580916301 0.4103633222087819 +Nuclear inner membrane 11 23 2.3784665574334336 0.0173848138024879 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.2998630597214531 0.1835089509173778 0.3339976348230559 0.0801176308941427 2.3975686123427828e-05 +Proteasome core complex beta subunit complex 5 7 2.3524658544521477 0.0186494019243264 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0024360578362321 0.0007972103198291 0.0031504918831051 9.14133433735114e-07 9.4206715064497e-07 +Proteasome core complex 5 15 2.3355431388016266 0.019515065068731 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 0.0088086754062598 0.0029386578360865 0.0113213926532688 3.830880641039723e-05 9.937036022358197e-05 +Mib complex 3 10 2.292972874949512 0.0218495666496574 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.0051636995807174 0.0017062060788896 0.0066572828402184 0.0033170374819039 0.0027630263410089 +Cis golgi network 5 12 2.276989918686462 0.022786827642079 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.2817714620506266 0.01497108596825 0.0538434207197609 0.0140312853386763 0.0105883475769395 +Golgi lumen 0 5 2.2577011939772 0.0239642947530218 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.2377412222279282 0.1430638950507344 0.266209970857853 0.5428479192551358 0.7970946997430631 +Pore complex 1 8 2.056706456585542 0.0397144707315257 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0088086754062598 0.0786913117950012 0.0113213926532688 0.0621585272883563 0.1985866733922443 +Calcium channel complex 3 9 2.05666245649514 0.0397187059074137 2.4150485436893203 7.298543689320389 0.1538765288718164 0.4525613292140901 1.4615016707365889 1.3130036030733032 1.08449347730351 0.3081575616966512 1.0 0.1049896535105009 0.1993869387044997 0.0020400745925255 0.0233101974365333 +Crd mediated mrna stability complex 1 6 2.017814493699684 0.043610584839371 1.9733009708737863 5.910194174757281 0.3271204777544745 0.5413593466387774 1.5206557657669346 0.2859033735288774 0.8816813816887278 0.3185396579284427 1.0 1.0 1.0 0.0081566962170519 0.0309764532364539 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4966c8fda0584d62ba9102f1acc96cd3d16a9974 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 904, + "title": "Average number of proteins per term", + "value": 28.13274336283186 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b2856d6d11bdf1d5e04afacbbbbafbba8b3e7d91 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..21869d60470f96d0260327e07297c277eb0d9c26 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,244 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Outer membrane 0.4820666166963599 3.1685956357598135 0.0015317734466184 0.7498725825370633 0.6866430729479824 83 O75431,P57105,Q5HYI7,P33121,Q6NUM9,Q9NX63,P21796,Q13505,Q9UKU0,Q9NS69,Q8N4H5,P61970,P52789,P30536,Q96TC7,Q99536,P50402,P45880,O00264,O43169,Q9BUK6 21 +Intrinsic component of mitochondrial membrane 0.6662282190829525 2.834741192570178 0.0045862823365241 0.9843226104870058 0.6866430729479824 50 O75431,Q99595,O60830,P50336,Q8TB36,P57105,O75880,Q5HYI7,Q15070,Q9NX63,Q9H3K2,Q96NB2,Q9H4I9,Q13505,O14925,Q96AQ8,Q9Y2R0,Q16891,Q9BPX6,Q9Y4W6,Q16134,Q8IXI1,Q8IWA4,Q9GZY8 24 +Intrinsic component of organelle membrane 0.494139322621507 2.794336806677556 0.0052006282279211 0.9910278998747708 0.6866430729479824 131 Q99595,O75431,O60830,P50336,Q8TB36,P57105,O75880,Q5HYI7,O14975,Q5XKP0,Q8TB61,Q15070,P42892,Q96A33,Q9H3K2,Q9NX63,Q96NB2,Q9H4I9,Q13505,O75844,Q03519,O14925,Q96AQ8,Q86UP2,Q9Y282,P51572,Q14739,P56589,Q9Y2R0,Q9NQC3,P04439,Q8TCT9,P49069,Q16891,Q99442,Q86XL3,Q9BTV4,Q9BPX6,Q15629,Q9Y4W6,Q16134,Q8IXI1,O15118,Q8IWA4,Q86Y82,Q9GZY8,O95470 47 +Intrinsic component of mitochondrial inner membrane 0.6986429590676478 2.7434319233654625 0.0060800653604999 0.9959666431999236 0.6866430729479824 35 O75431,Q99595,O60830,P50336,Q13505,O75880,O14925,Q96AQ8,Q5HYI7,Q16891,Q9Y4W6,Q16134,Q15070,Q9NX63,Q9H3K2,Q9Y2R0,Q96NB2,Q9H4I9 18 +Outer mitochondrial membrane protein complex 0.7574348452430865 2.7389143994066587 0.0061642420774394 0.9962639291273888 0.6866430729479824 15 O75431,Q13505,Q9NS69,Q8N4H5,Q5HYI7 5 +Intrinsic component of plasma membrane 0.4450897966793312 2.6649250390170485 0.0077005485654633 0.9990773284150472 0.6866430729479824 87 Q9UNN8,O43657,Q15043,P98172,P30825,Q8TDW0,Q08722,Q8TAD4,Q9UIQ6,O15121,Q8WTV0,P51572,Q99805,P04439,Q9Y666,O96005,O00264,O15031,P10586,P53985,Q99808,P41440,O15118,O43813,Q9BX67,Q9NR28,P11717 27 +Inner mitochondrial membrane protein complex 0.4644157423085643 2.649193021953772 0.0080684234933823 0.9993401110747704 0.6866430729479824 78 Q99595,O75431,O60830,P00403,Q5HYI7,Q9UDW1,Q9Y6M9,Q9NX63,Q9H4I9,Q13505,P62072,O75964,O96000,O43676,P00846,Q9Y584,P22695,P03915,Q96CU9,Q8IYU8,Q9BPX6 21 +Cell surface 0.461179770288696 2.5133265954556467 0.011959855770296 0.9999811100972452 0.6866430729479824 77 Q9UNN8,P00813,Q9HDC9,P55899,P08195,Q9UII2,P42892,Q08722,Q4VCS5,P17655,Q13740,P08183,Q8WTV0,Q9NWH9,P04083,P04439,Q96JJ7,P10809,Q8TCT9,O15439,O96005,P06576,O15031,P09525,P41440,P30040,Q99523,P11717 28 +Tim23 mitochondrial import inner membrane translocase complex 0.8796642231832195 2.4220805243319945 0.0154319305845571 0.9999992162901232 0.6866430729479824 7 Q99595,O60830 2 +External side of plasma membrane 0.6486388077478707 2.393085772470972 0.0167073348304798 0.9999997571988084 0.6866430729479824 22 P42892,O15439,P08183,P00813 4 +Nuclear inner membrane 0.6470895352279679 2.3784665574334336 0.0173848138024879 0.999999869785747 0.6866430729479824 23 Q5JTV8,Q9BTV4,O75844,Q8IXM6,P61970,P50402,Q13185,P62995,Q14739,P20700,Q03252 11 +Proteasome core complex beta subunit complex 0.8629869160646 2.3524658544521473 0.0186494019243264 0.9999999593491994 0.6866430729479824 7 P28070,P28072,P49721,P20618,Q99436 5 +Proteasome core complex 0.68305842779011 2.3355431388016266 0.019515065068731 0.9999999816938784 0.6866430729479824 15 P28070,P28072,P49721,P20618,Q99436 5 +Mib complex 0.7626692365373394 2.292972874949512 0.0218495666496574 0.9999999978781772 0.6866430729479824 10 O75431,Q13505,Q5HYI7 3 +Cis golgi network 0.7143704604588064 2.276989918686462 0.022786827642079 0.9999999991080544 0.6866430729479824 12 Q9NPR9,O95249,Q08379,O00461,Q16706 5 +Uniplex complex 0.9148624807064072 2.059743113836258 0.0394231054163647 1.0 0.86607935395715 4 Q8IYU8,Q9H4I9 2 +Pore complex 0.7531810457873306 2.056706456585542 0.0397144707315257 1.0 0.86607935395715 8 P21796 1 +Calcium channel complex 0.7337994310150124 2.05666245649514 0.0397187059074137 1.0 0.86607935395715 9 Q8IYU8,P17252,Q9H4I9 3 +Crd mediated mrna stability complex 0.8241683375589122 2.017814493699684 0.043610584839371 1.0 0.8959992885179877 6 P67809 1 +Mitotic spindle pole 0.6364509360137715 1.8680121992442584 0.0617603705359219 1.0 0.9794978063942714 12 Q96TC7,Q9UQE7,Q13123,Q96DB5,Q8WVM7,P53350,Q96GD4,Q8N3U4 8 +Endoplasmic reticulum golgi intermediate compartment membrane 0.5629753758922913 1.8197769848962195 0.0687929739850181 1.0 1.0 26 Q15904,Q96GC9,Q03519,Q08379,O15260,P56962,Q9Y282,P51572,Q8N511,Q10472,Q969X5 11 +Organelle envelope lumen 0.541893025111787 1.691214055047553 0.0907959275802088 1.0 1.0 39 Q9Y255,P62072,P50336,Q8IYU8,Q9BPX6,Q6FI81,O14925,Q96BR5,O95831,Q16891,Q96AY3,Q9Y3B8,P36551,Q9NR28,Q8N4Q1,P11717,P52888 17 +Paraspeckles 0.7320137961379164 1.6310129197139749 0.1028875934102093 1.0 1.0 6 Q15233,P23246 2 +Secretory granule membrane 0.4173952962167381 1.6093809390810538 0.1075330705590003 1.0 1.0 72 Q9NQX7,Q8TAD4,P07602,O15439,O15260,P42785,O15121,O14975,P30519,O00264,Q93050,P20073,Q07065 13 +Protein lipid complex 0.8940034769768676 1.559317983100435 0.1189211374899787 1.0 1.0 3 Q9UHG3 1 +Respiratory chain complex iii 0.6453926955204425 1.5484959026608662 0.1215029474532185 1.0 1.0 8 P22695,Q9UDW1,O14949 3 +Specific granule membrane 0.508576458199254 1.5354756962432483 0.1246670224935371 1.0 1.0 18 O15121,O14975,P30519,O00264,Q07065 5 +Proton transporting v type atpase complex 0.5916273565668335 1.5281854561347052 0.1264664987505921 1.0 1.0 11 Q15904,P36543,Q9Y487,Q93050,Q8N511 5 +Proton transporting two sector atpase complex 0.5141450035618845 1.5231042527484573 0.1277326250549184 1.0 1.0 22 Q15904,Q9Y487,P36543,O75964,P06576,P00846,Q93050,Q8N511,P24539 9 +Tim22 mitochondrial import inner membrane insertion complex 0.882848457490284 1.5177534160266244 0.1290765726334204 1.0 1.0 3 P62072 1 +Caveola 0.5283134056893555 1.5052144133052272 0.1322689607250611 1.0 1.0 16 Q8WTV0 1 +Haus complex 0.7727637319403813 1.5046935012325644 0.1324028946680902 1.0 1.0 4 Q9H6D7 1 +Lamin filament 0.8752584850711312 1.4894382137510556 0.1363720120780573 1.0 1.0 3 P02545 1 +Mhc class i peptide loading complex 0.7600236000412689 1.4539018630774507 0.1459735162238606 1.0 1.0 4 Q03519 1 +Nuclear pore nuclear basket 0.6570838356392183 1.4471680759328898 0.1478498553320815 1.0 1.0 7 Q8NFH5,P41208 2 +Golgi medial cisterna 0.854486133768346 1.4118355333705777 0.1579983931676394 1.0 1.0 3 O95249,Q16706 2 +Ciliary transition zone 0.6786809127367819 1.4015838801235103 0.161039543428352 1.0 1.0 6 A6NIH7 1 +Intrinsic component of mitochondrial outer membrane 0.5664353813341336 1.393622376435405 0.1634316677305076 1.0 1.0 11 Q8IXI1,Q9GZY8,P57105,Q8IWA4 4 +Mitochondrial protein containing complex 0.4079531534955859 1.369567045261899 0.1708220926173029 1.0 1.0 163 Q99595,Q7Z7F7,O60830,O75431,P00403,Q9NQ50,Q5HYI7,Q9UDW1,Q9Y6M9,Q9NX63,P21796,Q9H4I9,Q13505,P62072,Q567V2,Q9NS69,Q8N4H5,O75964,O43676,P00846,O14874,Q9Y584,P22695,P03915,Q8IYU8,Q9BPX6,Q9Y291 27 +Histone pre mrna 3 end processing complex 0.8426365199951211 1.3675197463468092 0.1714624522135108 1.0 1.0 3 P67809 1 +Side of membrane 0.4104672486031239 1.3535901054540085 0.1758671853831888 1.0 1.0 69 P00813,P55899,P10619,P63218,Q12959,P42892,Q4VCS5,P17655,Q13740,P08183,P51572,P04439,O00291,Q9UBI6,Q8TCT9,O15439,O96005,P41440,Q9H0H5,Q9NR28 20 +Oligosaccharyltransferase complex 0.5979972043277636 1.31809785085894 0.187470893861084 1.0 1.0 8 P04843,P04844,Q9H0U3,P46977,Q8TCJ2 5 +Neurofilament 0.8257748776508872 1.304442832688712 0.1920826391251855 1.0 1.0 3 P07197,Q16352 2 +Intrinsic component of synaptic vesicle membrane 0.5934905148053047 1.296041068148392 0.194961336415153 1.0 1.0 8 Q86Y82,P20339,O15126 3 +Dynactin complex 0.6498661293064854 1.2714101758360972 0.2035827643913781 1.0 1.0 5 O75935 1 +Er membrane insertion complex 0.8159869494290382 1.2678384820632198 0.2048556366066503 1.0 1.0 3 O43765,P46379 2 +Proton transporting two sector atpase complex proton transporting domain 0.5580864300766524 1.2658250632510253 0.2055757198615739 1.0 1.0 10 P00846,Q93050 2 +Organelle inner membrane 0.4516987163664269 1.2631418835428427 0.2065381942229411 1.0 1.0 250 Q99595,Q7Z7F7,O60830,P50336,Q70HW3,P00403,Q9HD33,Q5HYI7,Q15070,Q9H3K2,Q96NB2,O43772,Q9H4I9,Q9NX20,Q13505,P62072,Q567V2,Q3ZCQ8,P53701,P61970,O14925,Q96AQ8,O43676,O95831,P00846,Q14739,Q9Y2R0,Q9UBX3,Q10713,Q13423,P10809,Q9H1E5,P23786,P06576,Q69YU5,Q16891,P22695,Q9Y3D3,P03915,Q5T9A4,Q9H061,P24539,Q6DKK2,Q92665,Q9H2V7,Q9BQT8,P36551,Q9UDX5,O75431,Q9Y619,O75880,P49748,Q9UDW1,O75964,Q8NI60,P50402,Q9Y584,Q8IYU8,Q9BPX6,Q9Y291,P62995,Q9NQ50,Q9Y6M9,Q9NX63,Q03252,O75844,O96000,Q13185,Q96CU9,Q86Y39,Q8N183,Q16134,P20700,Q5JTV8,O75600,P22830,Q9P0J0,Q9Y6C9,Q8IXM6,O14949,Q9Y276,P34897,Q9BTV4,Q9Y4W6 84 +Micos complex 0.7106981438636303 1.2565184887586962 0.208928046887582 1.0 1.0 4 Q9NX63,Q16891 2 +Microbody membrane 0.4830958592322015 1.2545559961837205 0.2096399860932223 1.0 1.0 29 Q9UKU0,Q9BY49,Q9NR77,O14975,P33121,P40855,O75381,Q15067,P56589,P51648 10 +Myofilament 0.7101827676240277 1.2544534275311685 0.2096772434702765 1.0 1.0 4 Q9NYL9,P67936,P06753 3 +Striated muscle thin filament 0.7101827676240277 1.2544534275311685 0.2096772434702765 1.0 1.0 4 Q9NYL9,P67936,P06753 3 +Snare complex 0.4657540058230058 1.2516003803258051 0.2107155159425617 1.0 1.0 18 O95249,O95219,Q9P2W9,P56962,Q86Y82 5 +Microbody 0.4470556158671211 1.2346551553714884 0.2169588723836473 1.0 1.0 57 P34913,Q15126,O14975,P33121,Q15067,Q9UKU0,Q9NR77,O15254,Q8N4Q0,Q13011,P40855,O75381,O75874,P56589,P51648,P28288,P48735,Q9BY49,P08670 19 +Spliceosomal complex 0.3660035377864474 1.2199410842482428 0.2224872098536328 1.0 1.0 122 Q9Y5S9,Q7RTV0,O75940,P62312,Q8IWZ8,Q13123,P31942,P52597,O43290,P19338,P61978,P08621,P67809,Q9NW64,Q07955,O60506,O75934,Q9UKM9,P51991,P52756,P17844,P54105,P22626,Q9P013,Q9P2K5,P09012,Q14011,Q86V81,P31943,Q13595,Q12972,Q9H2H8,Q15428,O43390,Q8WWY3,Q14331,Q96I25,Q9UKA9,P62995,P07910,P98179,Q12874,Q96E39,P55081,P38159,P09651 46 +Mitotic spindle microtubule 0.6347307131062493 1.2106912527087372 0.2260137561035371 1.0 1.0 6 Q9H6D7 1 +Myelin sheath abaxonal region 0.6354455539692092 1.209225016702115 0.2265764091621809 1.0 1.0 5 Q96A65,P05556,Q12959 3 +Azurophil granule membrane 0.4668888709402253 1.1924308223422992 0.2330923606660522 1.0 1.0 23 Q9NQX7,O15260,P42785,P07602 4 +Plasma membrane raft 0.4683288826817675 1.1914719381514138 0.2334683665997374 1.0 1.0 24 Q8WTV0,P41440 2 +Perinuclear endoplasmic reticulum 0.6287836469367037 1.1804991369149025 0.2378017535216319 1.0 1.0 5 Q9H4L5,P17655,P51572 3 +Messenger ribonucleoprotein complex 0.6268400847027167 1.172120217425502 0.2411487939744514 1.0 1.0 5 P67809,Q99729 2 +Nbaf complex 0.5639994073816609 1.151339726386619 0.2495924997870231 1.0 1.0 8 Q92785,Q969G3,O14497,Q8TAQ2 4 +Vacuolar proton transporting v type atpase v0 domain 0.7805598005818389 1.1356451831337036 0.2561050908863622 1.0 1.0 3 Q93050 1 +Proton transporting v type atpase v0 domain 0.7805598005818389 1.1356451831337036 0.2561050908863622 1.0 1.0 3 Q93050 1 +Organelle membrane contact site 0.4574680534668834 1.1261480968894042 0.2601028385995043 1.0 1.0 17 O95772,Q96TC7,Q96N66,O43865,P51572 5 +Ciliary basal body 0.4649846428071247 1.1108229401230958 0.2666445701093078 1.0 1.0 16 P28070,Q9UPT5,P41208,O43805 4 +Nuclear pore central transport channel 0.6724151723432825 1.1033130121758932 0.2698912577757697 1.0 1.0 4 P61970 1 +Intrinsic component of peroxisomal membrane 0.6102183615298791 1.1005237900254592 0.2711039700418176 1.0 1.0 5 P56589 1 +External side of apical plasma membrane 0.9761904761904756 1.0909496141293684 0.2752950540623333 1.0 1.0 2 P08183 1 +Prefoldin complex 0.6072249205867584 1.087647040371296 0.276750955713831 1.0 1.0 5 O15212 1 +Pericentric heterochromatin 0.5234284532609644 1.0849709349383514 0.2779345284820638 1.0 1.0 10 P07199,Q13185,P46100 3 +Neuromuscular junction 0.4404876457522801 1.0167977842411025 0.3092496364205499 1.0 1.0 17 Q14168,P57105,P17252,P07196,P46939 5 +Centriolar satellite 0.4350458715858513 1.0161388542709269 0.309563268942401 1.0 1.0 20 Q9UPT5,Q86UY6,P41440 3 +Npbaf complex 0.5349752031154228 1.0088061588736952 0.3130676067858067 1.0 1.0 8 Q92922,Q8TAQ2,Q969G3,O14497,Q96GM5 5 +Platelet alpha granule lumen 0.4943494339645906 1.0054536514669794 0.3146784566031442 1.0 1.0 11 Q8NBX0 1 +Extrinsic component of mitochondrial inner membrane 0.5859066831160912 0.9961962552136638 0.31915479856537 1.0 1.0 5 Q8NI60 1 +Nuclear outer membrane 0.505934025628234 0.9938073679978772 0.3203166583685743 1.0 1.0 10 P61970,P50402 2 +Endoplasmic reticulum lumen 0.4172981569554429 0.9903748666885256 0.321990925418175 1.0 1.0 58 Q9BTV4,Q14257,Q15293,Q9H173,Q9BTY2,O14975,Q13217,Q32P28,Q96AY3,Q02818,O75718,Q9NWM8,Q9Y680,Q07065,O43852,P13674 16 +Mitotic spindle midzone 0.5280103714755957 0.9746772594826848 0.3297203765315908 1.0 1.0 8 Q96GD4 1 +Gtpase complex 0.5527118592369291 0.9665705415934296 0.3337587669353428 1.0 1.0 7 Q14344,P04899,Q9UBI6,P63218 4 +Phagophore assembly site 0.5526455075925147 0.9662659798646824 0.3339111047177592 1.0 1.0 7 Q7Z3C6,Q96GC9,Q86Y82 3 +Lumenal side of endoplasmic reticulum membrane 0.552151528826718 0.9639987525253598 0.3350465513011076 1.0 1.0 7 P51572,Q8TCT9 2 +Lumenal side of membrane 0.5077942171263505 0.9364554698461824 0.3490387295940027 1.0 1.0 9 P04439,P51572,Q8TCT9 3 +Camp dependent protein kinase complex 0.6286986724281646 0.9298859403870244 0.3524301432526087 1.0 1.0 4 P17252 1 +Euchromatin 0.4300997109674742 0.9193512601766444 0.3579118740514828 1.0 1.0 25 O75475,Q99496,P16403,P35222,P07305,Q9H6U6,Q9NQT4,Q13185,Q9GZS3,P16402,P38159,Q8IZL8,Q9UBL3 13 +Integral component of synaptic vesicle membrane 0.7196514531180548 0.9112690539558844 0.3621536275572694 1.0 1.0 3 Q86Y82 1 +Pronucleus 0.5645764732353162 0.9053659545284444 0.3652715459231508 1.0 1.0 5 O43823,P49454 2 +Platelet alpha granule 0.430895800327826 0.8988017989479805 0.3687582417304744 1.0 1.0 16 Q96JJ7,Q9BX10,Q8NBX0,Q9Y6I9,Q9H267 5 +Endoplasmic reticulum tubular network membrane 0.913894324853227 0.8821731986970988 0.3776831530265232 1.0 1.0 2 Q9NQC3 1 +Ciliary base 0.534090754352761 0.8813817292602846 0.3781112433279094 1.0 1.0 7 P17252 1 +Myelin sheath 0.4504430183473437 0.8779986919788666 0.3799444285569451 1.0 1.0 13 Q96A65,Q9BX67,Q9NR77 3 +Presynaptic cytosol 0.5512834389796567 0.849261096492508 0.395736023257462 1.0 1.0 5 P05771 1 +Proton transporting atp synthase complex coupling factor f o 0.5232260317466286 0.8320120747560342 0.4054021289447691 1.0 1.0 7 P00846 1 +Outer kinetochore 0.5468316691206745 0.830840688126214 0.4060636337155343 1.0 1.0 6 Q8NFC6,P49454,P53350 3 +Spindle pole centrosome 0.5192379996407148 0.8139684554285337 0.4156630222639847 1.0 1.0 7 Q96GD4,P50402 2 +Postsynaptic density membrane 0.5189840161314898 0.8128208864714174 0.4163207586467135 1.0 1.0 7 P57105,Q14168 2 +Proton transporting atp synthase complex 0.4575175831007343 0.8089588769178124 0.418538800796286 1.0 1.0 11 P00846 1 +Golgi cisterna 0.3955825392121553 0.7867220152936147 0.4314446136113488 1.0 1.0 18 P04439,O95249,Q8TBA6,Q08379,O00461,Q99523,P51572,Q10713,Q16706 9 +Postsynaptic specialization intracellular component 0.5360550662020297 0.7856174865789186 0.4320916167915118 1.0 1.0 5 O60716,Q9UQB8 2 +Chromosome passenger complex 0.6786296900489209 0.7644037580957396 0.4446266699028778 1.0 1.0 3 Q53HL2,Q96GD4 2 +Hops complex 0.6777127018254636 0.7611787333239998 0.4465503188107105 1.0 1.0 3 Q9P253 1 +Postsynaptic density intracellular component 0.5840472156566273 0.7567624164769567 0.4491922130961501 1.0 1.0 4 Q9UQB8,O60716 2 +Dendrite cytoplasm 0.4443458678647495 0.7398144791262644 0.4594125721464155 1.0 1.0 11 Q00577,P23246,Q9UQB8 3 +Smooth endoplasmic reticulum membrane 0.8695368558382204 0.7392623735040282 0.4597476924130261 1.0 1.0 2 O00264 1 +Mitochondria associated endoplasmic reticulum membrane 0.4533916939681423 0.7238137493718626 0.4691800870592129 1.0 1.0 10 Q96N66,O43865,P51572 3 +Extrinsic component of endosome membrane 0.6639477977161443 0.7131362102626576 0.4757614745457137 1.0 1.0 3 P04083,Q9Y5X3 2 +Intrinsic component of golgi membrane 0.4492345684106381 0.7028950961721918 0.4821211274238683 1.0 1.0 10 Q8TB61,Q9Y282 2 +Schaffer collateral ca1 synapse 0.3893616048397373 0.6930684491904218 0.4882665965446988 1.0 1.0 17 Q9UQB8,Q96EV8,O14936,Q16352,P35222,P35080,Q08209,Q9BVA1,P07196,O60716 10 +Contractile ring 0.5653894132087078 0.686398258586964 0.4924620023112633 1.0 1.0 4 P46939 1 +Mcrd mediated mrna stability complex 0.511599875876307 0.6852510476088108 0.4931855163358394 1.0 1.0 5 O60506 1 +Endoplasmic reticulum golgi intermediate compartment 0.400149942579651 0.6623473210604894 0.5077486562293063 1.0 1.0 47 Q15904,Q03519,Q08379,O15260,Q9Y282,P80303,Q02818,Q8N511 8 +9plus2 motile cilium 0.3777610886996387 0.6397292746556686 0.5223486198189009 1.0 1.0 20 P10809,P17252 2 +Compact myelin 0.8369210697977694 0.6386288858973768 0.5230643852350221 1.0 1.0 2 Q9NR77 1 +Anchored component of synaptic vesicle membrane 0.4888898857284346 0.5947213248554378 0.5520297649320107 1.0 1.0 5 P20339,Q15286,P20337 3 +Microbody lumen 0.3691306127277189 0.5852400235043016 0.558386336610265 1.0 1.0 20 O75874,Q15067,O15254,Q13011 4 +Mitochondrial envelope 0.4277601995427781 0.575618189292342 0.5648732837704142 1.0 1.0 315 Q99595,Q7Z7F7,O60830,O75431,P57105,O75600,Q70HW3,P00403,P22830,Q9NQ50,Q5HYI7,Q9UDW1,P33121,Q9Y3B8,Q9P0J0,Q9Y6M9,Q9NX63,P21796,Q8N4Q1,O43772,Q9H4I9,P52888,Q9Y6C9,Q13505,P62072,Q567V2,Q9NS69,Q8N4H5,Q9UKU0,O75964,O96000,O15121,O43676,O95831,P00846,Q8NI60,P17252,P52789,Q9Y2R0,Q9UBX3,Q10713,P30536,Q13423,Q96TC7,P10809,Q99536,P23786,Q9Y584,Q69YU5,P22695,P45880,Q96AY3,O00264,O43169,P03915,Q9H061,Q9BUK6,Q96CU9,Q5U5X0,Q8IYU8,Q86Y39,Q6DKK2,Q9BPX6,Q8N183,Q96BR5,Q9Y291,Q16134,Q9H2V7,Q9BQT8,Q9NR28 70 +Postsynaptic specialization membrane 0.4198430984425892 0.5580987271950835 0.5767769697097191 1.0 1.0 10 Q14168,P57105,P52292 3 +Xy body 0.6171305723629863 0.556032129834565 0.578188890509076 1.0 1.0 3 P16104 1 +Swi snf complex 0.4076788267783611 0.552891372096335 0.5803377957770353 1.0 1.0 11 Q86U86,Q92922,Q92925,Q8TAQ2,Q969G3,O14497,Q96GM5 7 +Protein complex involved in cell adhesion 0.6159869494290211 0.5523398129515708 0.5807155582872812 1.0 1.0 3 P05556,Q9BX67 2 +Catalytic step 2 spliceosome 0.3425846792252601 0.5492962416653472 0.5828021661599507 1.0 1.0 67 P52597,P22626,O43390,P61978,P07910,Q07955,O75934,O60506,Q9UKM9,P38159,P51991,P09651,P31943 13 +Neuron projection terminus 0.369899199985463 0.5336678676378813 0.5935713440687447 1.0 1.0 16 P05771,Q9UQB8 2 +Chromaffin granule 0.8007175472928763 0.5326813816892626 0.5942541564404495 1.0 1.0 2 P20073 1 +Chromaffin granule membrane 0.8007175472928763 0.5326813816892626 0.5942541564404495 1.0 1.0 2 P20073 1 +Transcription repressor complex 0.391677104164069 0.5301335034959938 0.5960193713591804 1.0 1.0 12 Q9UHI6,P07305,P45973,P51858,P04637 5 +Basolateral plasma membrane 0.3823200031734754 0.5198625405409462 0.6031593857023856 1.0 1.0 46 P57105,O14936,Q14168,P08195,Q99808,O15439,Q15043,P41440,Q07954,Q12959,Q9Y6M7,P30825,Q96RT1,P53985,P35670,Q6P4Q7 16 +Brush border membrane 0.4313705161863895 0.515771792495956 0.6060138057234978 1.0 1.0 8 P40855,P41440 2 +Mrna cleavage and polyadenylation specificity factor complex 0.4106005440892832 0.5139646247695665 0.6072767234992085 1.0 1.0 10 Q6UN15,Q8N684 2 +Growth cone membrane 0.7915851272015548 0.5070798219655837 0.6120988123570892 1.0 1.0 2 Q9UPT5 1 +External encapsulating structure 0.3803354505097603 0.5012198596850989 0.6162163989611233 1.0 1.0 36 P07602,P50995,Q92896,Q32P28,P08133,P55081,P20073 7 +Golgi cisterna membrane 0.3841832920458549 0.4925172638509605 0.6223537206492167 1.0 1.0 12 Q08379,O00461,Q10713 3 +Granular component 0.508812010443861 0.4842353297776814 0.6282188661626797 1.0 1.0 4 P22087,Q14684,Q9NXV6 3 +Hippocampal mossy fiber to ca3 synapse 0.4584668138036693 0.4788856869786734 0.6320199538601954 1.0 1.0 5 P63104,O60716 2 +Rpap3 r2tp prefoldin like complex 0.4412659719312015 0.4758274153902797 0.634197336701245 1.0 1.0 7 O15212,Q9UBK9 2 +Box h aca rnp complex 0.500315875831177 0.4557707822267577 0.6485548165869621 1.0 1.0 4 Q14978 1 +Box h aca snornp complex 0.500315875831177 0.4557707822267577 0.6485548165869621 1.0 1.0 4 Q14978 1 +Intermediate filament 0.3434120428251831 0.4444685448285638 0.6567038657508117 1.0 1.0 19 Q16352,P07197,P02545,P08670,Q03252 5 +Nucleotide activated protein kinase complex 0.577682942671333 0.4336657444745362 0.664531185421547 1.0 1.0 3 P13861 1 +Cation channel complex 0.3629858496436968 0.4332529205107668 0.6648310366388688 1.0 1.0 14 Q8IYU8,P17252,Q9H4I9 3 +Cyclin dependent protein kinase holoenzyme complex 0.4021039509301993 0.4287154187166014 0.6681303384265689 1.0 1.0 9 Q14004 1 +Extrinsic component of postsynaptic membrane 0.4902868281196881 0.4229515336895158 0.6723306225464503 1.0 1.0 4 P52292 1 +Collagen containing extracellular matrix 0.3617011991825122 0.4190744703901743 0.6751617078667818 1.0 1.0 30 P07602,O14936,P50995,Q32P28,P08133,P51858,P20073,P09525 8 +Mitochondrial crista 0.4853133159268891 0.4070088886592498 0.6840014598163353 1.0 1.0 4 P18031,O60313,P07948 3 +Myosin ii complex 0.484334203655344 0.4038973500086382 0.686288205118289 1.0 1.0 4 P35579,P60660,P35580 3 +Dendritic shaft 0.4372923471381948 0.4029744700603968 0.6869670057812485 1.0 1.0 5 Q9UQB8 1 +Condensed chromosome centromeric region 0.3017662442023286 0.3970051097235794 0.6913636925913411 1.0 1.0 74 Q6P1K2,Q96DE5,Q92674,P53350,Q13561,Q9BZD4,Q8NFC6,Q13185,Q96DY7,P12270,Q12769,Q8NFH4,Q9HD42,P07199,P45973,O14974,P46100,O75935,Q96GD4,P49454 20 +Prespliceosome 0.4029411764705903 0.3919960749403776 0.6950611139420526 1.0 1.0 8 Q15428,P26368,Q9Y383,P08621,O75400,O75533,Q15459 7 +Chromocenter 0.4362922559637573 0.391341027971993 0.6955451761588907 1.0 1.0 6 Q53HL2,P45973,P83916,Q96GD4 4 +Cytosolic region 0.3928708610394221 0.3884908750832052 0.6976528054850646 1.0 1.0 9 P05771 1 +Gamma secretase complex 0.745270711024135 0.3854884025321464 0.6998755972789368 1.0 1.0 2 P49755 1 +Condensed nuclear chromosome 0.330095324507261 0.3836736149203668 0.7012203709126994 1.0 1.0 18 Q9HD42,Q92791,Q9UEY8,P16104,Q9UQE7,P53350,Q8N3U4,Q9NQS7,Q9H6R4 9 +Vacuolar membrane 0.3008068684537336 0.3770144676202256 0.7061628533143827 1.0 1.0 120 P10619,Q15043,P42785,P56962,Q93050,Q9Y6I9,Q14108,P42892,Q7Z3C6,Q9UIQ6,Q8WTV0,Q07065,Q9NQX7,Q8IV08,O15260,Q9HBH5,P08133,Q8N511,O95772,Q9HD42,P07602,P41440,P36543,Q9P253,Q9H2V7,O15118,Q99523,P53680,O95721,Q16625,Q07954 31 +Ficolin 1 rich granule membrane 0.3395211041089426 0.3675130081792214 0.71323639057095 1.0 1.0 16 P42785 1 +Membrane microdomain 0.331615594393925 0.3593518271253818 0.7193319075108633 1.0 1.0 64 P41440,P98172,O15118,Q8WTV0,P17252,P21796,Q86Y82 7 +Extrinsic component of synaptic membrane 0.4241094243544516 0.358069408659621 0.7202913716445352 1.0 1.0 5 P52292 1 +Sarcoplasm 0.3325977579291057 0.3522399265673265 0.7246583361759595 1.0 1.0 21 P52789 1 +Centrosome 0.3187360293345207 0.3478890134908089 0.7279235364952474 1.0 1.0 147 Q9Y5Y2,Q9UNN8,P41208,Q7Z4H7,P28074,P17252,P52789,O75934,Q13561,O95684,Q86UY6,O43805,P50402,P53985,Q9UBK9,Q6DKK2,P41440,Q9H6D7,O14974,O75935,Q5VU43,Q96GD4,P55081,P49454,Q9UPT5,Q96JB5 26 +Filopodium membrane 0.7279843444226932 0.3440635827889382 0.7307984695075049 1.0 1.0 2 P46939 1 +Mitochondrial large ribosomal subunit 0.3520560124847944 0.3299904021280487 0.7414072142952106 1.0 1.0 34 Q7Z7F7 1 +Intrinsic component of nuclear inner membrane 0.3980420782020473 0.3091897022748647 0.7571772267870613 1.0 1.0 7 Q14739,Q9BTV4 2 +Golgi stack 0.3337519723682525 0.3065837474157478 0.7591602259555148 1.0 1.0 25 P04439,O95249,Q8TBA6,Q08379,O00461,Q99523,P51572,Q10713,Q16706 9 +Spindle midzone 0.3154516344549282 0.3034400219065813 0.7615545494219815 1.0 1.0 18 Q14247,Q14980,Q9NVJ2,Q86Y91,Q9H0H5,Q53HL2,Q96GD4,P53350 8 +Transporter complex 0.3331614941109583 0.2915121317833903 0.7706596667704566 1.0 1.0 60 O14949,Q8IYU8,P62072,Q86Y39,Q96CU9,Q9BPX6,O96000,O43676,Q9UDW1,Q8TDW0,P22695,P17252,Q9P0J0,Q9Y6M9,O75381,P03915,Q9H4I9 17 +Cohesin complex 0.4009712248800953 0.2843106381236274 0.7761723343489755 1.0 1.0 5 Q8WVM7 1 +Nuclear pore outer ring 0.3759718940015262 0.2832013221662802 0.7770225148845937 1.0 1.0 8 Q8NFH4,Q9BW27,Q8WUM0,P57740,Q12769 5 +Nuclear lamina 0.4018756465108307 0.2756076983837179 0.7828493961497665 1.0 1.0 6 P02545,P20700 2 +Cdc73 paf1 complex 0.3956904995102741 0.2684671366766811 0.7883397677805235 1.0 1.0 5 Q8N7H5,Q6PD62,Q9GZS3,Q92541 4 +Sumo ligase complex 0.3981058131939923 0.2638381289702978 0.7919046525572593 1.0 1.0 6 Q96MG7,Q8IY18,Q96MF7,Q8WV22,P49792 5 +Catalytic step 1 spliceosome 0.3975220193271644 0.2620329433022756 0.7932960441922423 1.0 1.0 6 Q9Y5S9,Q9NW64 2 +Smooth endoplasmic reticulum 0.343088498153211 0.2594269564859423 0.7953058332093801 1.0 1.0 11 P56962,O00264,Q13217 3 +Proton transporting v type atpase v1 domain 0.37851260544562 0.2415533369565663 0.8091262830972461 1.0 1.0 7 Q15904,P36543 2 +Lateral element 0.6784083496412214 0.2390057783757474 0.8111011020820675 1.0 1.0 2 Q9UQE7 1 +Basal part of cell 0.3372950008181288 0.2387695299703637 0.8112842984829405 1.0 1.0 53 P57105,O14936,Q14168,P08195,Q99808,O15439,Q15043,P42785,P41440,Q07954,Q12959,Q9Y6M7,P30825,Q9NWH9,Q96RT1,P53985,P35670,Q6P4Q7 18 +Mhc protein complex 0.4994297269781027 0.2299788790774574 0.8181081819201628 1.0 1.0 3 P04439 1 +Mhc class i protein complex 0.4994297269781027 0.2299788790774574 0.8181081819201628 1.0 1.0 3 P04439 1 +Ciliary membrane 0.3868563474691996 0.2299012280585197 0.8181685220330568 1.0 1.0 6 O14936 1 +Postsynaptic endosome 0.4966622439545098 0.2239307353755431 0.8228111995813854 1.0 1.0 3 Q86Y82 1 +Nuclear inclusion body 0.3590702112294742 0.22042270972999 0.8255419605049994 1.0 1.0 8 Q86U42 1 +Proton transporting two sector atpase complex catalytic domain 0.3317402226575611 0.2150452966431063 0.8297320029804061 1.0 1.0 11 Q15904,P06576,P36543 3 +Transcription elongation factor complex 0.297589071235879 0.2130514222107668 0.831286854159081 1.0 1.0 18 Q8IXH7 1 +Nuclear speck 0.3274280531155911 0.2124744662732209 0.8317368959727651 1.0 1.0 176 Q86VM9,Q9P275,Q9Y5S9,O75940,O75600,P84103,Q96PK6,Q08170,Q9NYF8,P82979,Q93050,P23246,P43490,Q8WXF1,Q13242,Q15233,Q3ZCQ8,Q9P2N5,Q03519,Q92733,P08621,Q7Z4H7,Q86U42,Q07955,P17252,O75934,Q07065,O95400,Q9ULX6,Q9P013,Q14004,Q8IY18,P80723,P02545,Q86V81,Q53F19,Q12972,Q9BWF3,O75494,Q9H0E3,Q92841,P49756,Q9Y2W1,Q16629,P98175,Q96RT1,Q96T37 47 +Hulc complex 0.6581865622961438 0.2024644175711087 0.8395536730099569 1.0 1.0 2 O75150 1 +Myosin filament 0.484176182707974 0.1977348617486674 0.8432525124714114 1.0 1.0 3 P35579,P35580 2 +Cleavage furrow 0.3104339309976885 0.191426194303838 0.848191699426486 1.0 1.0 14 O75935,Q9H0H5 2 +Emc complex 0.3646751550767261 0.1836990406641311 0.8542495615413515 1.0 1.0 5 Q9NPA0,Q15006,Q8N766,O43402 4 +Apical plasma membrane 0.3286956888460995 0.1610430898538031 0.8720594627458329 1.0 1.0 49 Q8TAD4,Q99808,P41440,O15439,Q9Y6M7,P30825,O43865,P08183,P53985,Q16625 10 +Set1c compass complex 0.3512130681920541 0.1569819102733878 0.8752591048413245 1.0 1.0 7 Q8NFC6,Q9UBL3 2 +Cell cortex region 0.3318077803203654 0.1544990062247305 0.8772162947296442 1.0 1.0 9 P35222,Q14980,Q14203,P56545,P09496,P61163,Q7Z460,O60716 8 +Endoplasmic reticulum plasma membrane contact site 0.6167645140247772 0.1396036405199571 0.8889731640741365 1.0 1.0 2 Q9NTJ5 1 +Integrin complex 0.6157860404435641 0.1383139691659919 0.8899922858233533 1.0 1.0 2 P05556 1 +Prp19 complex 0.3185458451630608 0.1380106601305127 0.8902319926056119 1.0 1.0 10 O75934,Q9P013 2 +Sex chromosome 0.300591055415524 0.1360443059362077 0.8917862554669627 1.0 1.0 12 Q8IY18,P16104,P84243 3 +Nucleoid 0.3143985797286185 0.1292703026454504 0.8971437692929272 1.0 1.0 33 P21796 1 +Mitotic spindle 0.3194893770944321 0.1257520825973843 0.8999281731106643 1.0 1.0 54 Q96TC7,Q08379,Q9H6D7,Q86Y91,Q96DB5,Q7Z4H7,P12270,Q8WVM7,Q96GD4,Q8N3U4 10 +Ptw pp1 phosphatase complex 0.3742272441502144 0.1251415283513342 0.9004115068207761 1.0 1.0 4 O14974 1 +Golgi membrane 0.2810612714206647 0.118237344793347 0.9058796006135584 1.0 1.0 123 P52292,Q96CV9,O00461,Q8TB61,Q14108,Q10472,Q7Z3C6,Q6RW13,Q9P2W9,Q9Y282,Q8IZA0,Q8N6H7,P51572,P51151,Q10713,Q16706,P04439,Q15392,Q8IV08,Q8TBA6,Q7LGA3,O15260,Q92896,O95249,Q08379,O95197,Q9H3P7,P11717,Q86Y82,O95721 30 +Intraciliary transport particle 0.4388254486133635 0.1181426678276957 0.9059546161274368 1.0 1.0 3 A0AVF1,Q7Z4L5 2 +Presynaptic active zone cytoplasmic component 0.4386499404658425 0.1178827386111718 0.9061605704677652 1.0 1.0 3 O60716 1 +Acrosomal membrane 0.5991519895629368 0.1177453181571113 0.9062694578119004 1.0 1.0 2 Q14254 1 +Tubular endosome 0.3691253263707649 0.1161911939737862 0.907501015673877 1.0 1.0 4 Q9UNH7,O75436,Q9Y5X3 3 +Apical part of cell 0.3130592884194023 0.115508479127675 0.9080421000912824 1.0 1.0 58 Q8TAD4,Q99808,P41440,O15439,Q9Y6M7,P30825,O43865,P08183,Q16625,P53985,P41208 11 +Chitosome 0.5971950424005089 0.115492066393982 0.9080551084999516 1.0 1.0 2 Q96EV8 1 +Cation transporting atpase complex 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 1.0 3 P05023,P05026 2 +Atpase dependent transmembrane transport complex 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 1.0 3 P05023,P05026 2 +Sodium potassium exchanging atpase complex 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 1.0 3 P05023,P05026 2 +Brca1 c complex 0.4319738988580623 0.1082695812727056 0.913781851372435 1.0 1.0 3 P49959,Q92878 2 +Condensed chromosome 0.2667458648751188 0.1077316969420571 0.9142085253080374 1.0 1.0 106 O43823,Q6P1K2,Q96DE5,Q92674,P53350,Q8N3U4,Q13561,Q9BZD4,Q8NFC6,Q8IY18,Q96DY7,Q13185,P12270,Q12769,Q8NFH4,Q9HD42,Q92791,P07199,P46100,P45973,O14974,O75935,Q8WVM7,Q96GD4,P49454 25 +Cytolytic granule 0.3612924281984392 0.1031861211815429 0.9178152548037086 1.0 1.0 4 Q01085,Q9NVJ2,P27797 3 +Endocytic vesicle 0.2472738633499371 0.101866966373171 0.9188622705428182 1.0 1.0 83 P04439,Q4VCS5,Q03519,P50995,O00461,P53680,O14964,Q8WTV0,Q93050,P51151,Q14108,Q14C86,P11717,Q86Y82,Q16625,P08670,Q07954 17 +Synaptic vesicle membrane 0.2829742566527983 0.1005912381000903 0.9198749524089936 1.0 1.0 15 P20339,Q96EV8,O15126,Q86Y82,P20337 5 +Centriole 0.2770244298179942 0.0958293142839514 0.9236561350629322 1.0 1.0 20 O95684,P41208 2 +Intrinsic component of endoplasmic reticulum membrane 0.316850292139207 0.0952671999503942 0.9241025947765948 1.0 1.0 51 P04439,O95470,Q8TCT9,O75844,Q03519,Q15629,P49069,Q86UP2,O14975,Q8TB61,Q9Y282,Q99442,P51572,Q96A33,Q86XL3,Q9NQC3 16 +Extrinsic component of cytoplasmic side of plasma membrane 0.2702525418169893 0.0817036452554528 0.9348823795592128 1.0 1.0 19 Q15334,O00291,Q14344,Q9UBI6,Q9Y5X3,P63218,Q9H0H5,P04899,P09471,Q9BSJ8,A0FGR8,Q96A49,P29992,P07948,P08754,Q9Y5X1,P46940,P63000 18 +Nuclear membrane 0.264247738307878 0.0808975185601813 0.9355234534012458 1.0 1.0 106 Q5JTV8,Q6NUM9,Q9BTX1,Q03252,O75844,P49903,P61970,Q8IXM6,Q8NFH5,P67809,Q14739,Q9H4L5,P50402,Q13185,P12270,P02545,Q8N1F7,P09525,Q9BTV4,P11802,P62995,Q9BW91,Q9H2V7,Q99523,Q96RT1,P20700 26 +Lipid droplet 0.2893875090212307 0.0599565233125381 0.9521902617299034 1.0 1.0 28 Q01105,P51572,Q8NBX0 3 +Extrinsic component of organelle membrane 0.2735084414393998 0.0580329566909968 0.953722377110578 1.0 1.0 13 P49748,Q8NI60,P04083 3 +Mrna cleavage factor complex 0.2744445626112509 0.0577070878013552 0.9539819478578596 1.0 1.0 12 Q6UN15,Q8N684 2 +Endocytic vesicle lumen 0.3125408229915068 0.0565721123459802 0.9548860500798028 1.0 1.0 6 P27797,P14625,O14964,Q9Y4L1,P07900 5 +Cell pole 0.3844462828505344 0.0547299807919951 0.956353583933322 1.0 1.0 3 P08195 1 +Pwp2p containing subcomplex of 90s preribosome 0.2954619653934118 0.0515180123492695 0.9589127491304256 1.0 1.0 5 Q9NYH9,Q15269,Q9Y5J1,Q8NI36 4 +Proteasome complex 0.3098648314960889 0.0510907154573078 0.9592532343238516 1.0 1.0 47 P49721,P28070,P28072,P20618 4 +Signal peptidase complex 0.3785385967694165 0.0497896821083033 0.9602899889711968 1.0 1.0 3 Q15005 1 +T tubule 0.3074158771643243 0.0495537501541962 0.9604780033492188 1.0 1.0 7 Q09666,P05026,P30626,O75298,P05023,P35241 6 +Sex chromatin 0.3774877650897238 0.0489475674503075 0.960961080923764 1.0 1.0 3 Q99496,O75367 2 +Cul4 ring e3 ubiquitin ligase complex 0.2908912830558353 0.0456277283162828 0.963606968182206 1.0 1.0 5 Q13620,Q9NV06,Q92990,Q9NXF7 4 +Sin3 complex 0.3699836867862976 0.0432469299647451 0.9655046953578748 1.0 1.0 3 Q96ST3,Q9UBU8 2 +Endoplasmic reticulum palmitoyltransferase complex 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Palmitoyltransferase complex 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Mcm complex 0.3024167210973201 0.0403133363501646 0.9678433215527612 1.0 1.0 6 P25205,P33991,Q14566,P33993,P49736 5 +Ciliary plasm 0.2623948605145111 0.0364069551806424 0.9709578684253992 1.0 1.0 15 P17252,Q10713 2 +Exocyst 0.2969396391452826 0.032251979483978 0.9742711040825268 1.0 1.0 6 Q9UPT5,O60645 2 +Risc loading complex 0.3520391517128862 0.0317192620387685 0.9746959337293724 1.0 1.0 3 Q08211,O75569 2 +Node of ranvier 0.3486580130537434 0.0298573650948242 0.9761808084021784 1.0 1.0 3 Q12959 1 +Kinesin complex 0.2590338242918673 0.0212121145406557 0.9830764504514592 1.0 1.0 13 Q86Y91 1 +Oxidoreductase complex 0.2922981071638488 0.0196329063158555 0.984336213443746 1.0 1.0 62 O14949,Q86Y39,Q96CU9,O96000,O43676,Q9UDW1,O14874,P22695,Q9P0J0,Q9Y6M9,O43169,P03915,P13674 13 +Cell tip 0.3333333333333239 0.0192058631826091 0.984676880323046 1.0 1.0 2 Q9BTU6 1 +Protein phosphatase type 1 complex 0.3140900195694645 0.0190170401869799 0.984827511764362 1.0 1.0 2 Q9UQ13 1 +Immunological synapse 0.2575542260301794 0.0173010417318086 0.9861964545465968 1.0 1.0 12 Q8WUM4,Q13740,Q12959,O15400,Q9UJZ1 5 +Ribbon synapse 0.2764360313315948 0.0154457213478373 0.9876765874081016 1.0 1.0 4 Q05193,P16615,P56545 3 +Chromosome centromeric region 0.2482374766623263 0.0080461071525805 0.9935802045978868 1.0 1.0 95 Q6P1K2,Q96DE5,Q92674,P53350,Q8N3U4,Q13561,Q9BZD4,Q8NFC6,Q8IY18,Q96DY7,Q13185,P12270,Q12769,Q8NFH4,Q9HD42,P07199,P46100,P45973,O14974,O75935,Q8WVM7,Q96GD4,P49454 23 +Box h aca telomerase rnp complex 0.2639477977161539 0.0062730900333133 0.9949948311408638 1.0 1.0 3 Q9NX24,Q9NY12 2 +Mll3 4 complex 0.2525285481239842 0.0053008557513642 0.995770548844228 1.0 1.0 3 P61964,Q9UBL3 2 +Specific granule 0.2928361435115138 0.0014519760837663 0.998841491107176 1.0 1.0 38 P50995,O15121,O14975,P30519,O00264 5 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2eb1eb2c9539661308628ed9a35062c2a35582ec --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystroglycan complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiia complex", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C12orf43", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C3orf58", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARS2", "CASK", "CAST", "CBFB", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPP", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG4", "COG6", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2A1", "GTF2E2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISOC1", "IST1", "ITCH", "ITGB1", "ITM2C", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5DC3", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGGT1B", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPAN", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAMM41", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLK2", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41B", "TMEM43", "TMEM65", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UGT8", "UHRF1", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H14", "ZC3H18", "ZCCHC8", "ZCRB1", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC4", "ABCD3", "ACADVL", "ACBD3", "ACOX1", 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sha256:9c8d39660dd4e07b976acb09fe4f81655b4e33201bd88918332bdc12aa83d57d +size 145949 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..aae2e52ebec19fb6d2fbd1915c8b21af015bd642 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4f109d1d8dfef31ab8d9100758759f5377f689d6fd5a7ee8b8a98b09b8872aa +size 127757 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c7abf847f3f6c48910ae3e869ed00fcb48d52a3c --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,30 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cholesterol binding 9 13 2.8050796041699804 0.0050304154446254 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0019954707498821 0.134742527043449 0.0001815434943904 5.536060276050235e-06 8.288637798262085e-07 +Tetrapyrrole binding 5 16 2.725926253657163 0.0064121323082277 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0105448820256187 0.0276250495673642 0.0149914480702132 0.0018183768983854 0.0457670040656382 +Sterol binding 9 16 2.661834055028786 0.0077716182259321 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0033838902651529 0.1594721229818057 0.0003733671894444 2.006126575116942e-05 5.387608889234745e-06 +Ion transmembrane transporter activity 26 104 2.6473888867443227 0.0081116011701878 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 0.0002670014299778 0.0160739624847947 0.0007663316842601 0.0001797587024086 0.0011254067529933 +Protein transporter activity 4 14 2.6260943059636994 0.0086370883955455 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0011653076128861 0.0002227197090729 8.694316847855437e-05 0.0002808583984775 0.0062616815035888 +Alcohol binding 9 16 2.6050972858198107 0.0091848176324793 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0085356676982441 0.2145132052152406 0.0013172485850202 0.0001800616428063 0.0001179839212013 +Peptide binding 19 72 2.601531490949639 0.0092808543966873 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 0.0079550349877139 0.0333931709842731 0.0135319942444888 0.0029371177900416 0.0002647762385188 +Threonine type endopeptidase activity 5 8 2.514368349118331 0.0119245814539405 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.003028417017274 0.0009934566258862 0.0039135152062846 1.7923085924657402e-06 2.2585304294532336e-06 +Metalloendopeptidase activity 6 14 2.5029176928877432 0.012317418538212 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.0026332302241178 0.1471951297158956 0.0038117145357013 0.0078094686864188 0.0045924061823516 +Steroid binding 11 22 2.4762362989445337 0.0132775668437721 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0080720369936635 0.2107016729382093 0.0012207780133745 2.1177342424249217e-06 2.672510894072328e-06 +Sphingolipid binding 2 6 2.428899068948021 0.0151447477524895 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0098558308218439 0.083126337411673 0.0126574737404708 0.0086586519898169 0.0539281835546241 +Organic acid transmembrane transporter activity 7 22 2.35506394463138 0.0185195185105728 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0195887015702512 1.0 0.0275216398495969 0.0058282629537454 0.0166822263622692 +Serine hydrolase activity 8 17 2.3519458524601338 0.0186754933085191 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0617915840696023 0.2068720246529641 0.0108939889611676 0.0057706709278987 0.0019780921583714 +Protein transmembrane transporter activity 3 11 2.312909769907419 0.0207276005590548 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0088086754062598 6.765318543664244e-05 0.0005309775927247 0.0006143549700213 0.0078812527225172 +Amyloid beta binding 5 11 2.3116497143887456 0.0207969946135226 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.269454491362586 1.0 0.3009165941166509 0.0591065206713347 0.0319540971359957 +Macromolecule transmembrane transporter activity 4 12 2.299060343521796 0.0215015129724172 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0121065438957565 0.0001122733832082 0.0008717411361388 0.0011814468070448 0.00223229240551 +Inorganic molecular entity transmembrane transporter activity 17 78 2.2635841697156205 0.0235997023964054 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0009919914701839 0.1110171748577526 0.0023050420516563 0.0022759844846867 0.0146287429575656 +Cation transmembrane transporter activity 34 74 2.2527248580652857 0.0242765025885576 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0132202709176096 0.024547037173099 0.0237167446771022 0.0243290919361026 0.0321940702471167 +Threonine type peptidase activity 5 9 2.216200427902681 0.0266777785956915 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.0059914484737676 0.001984476440523 0.0077184558590264 1.31526437712885e-05 2.7323384312904545e-05 +Lipopolysaccharide binding 2 6 2.191452596738593 0.0284190565011708 1.3325242718446602 6.762135922330097 0.8069967393930578 0.3801019166455804 1.1293139239074608 0.4639669608371066 0.8740381370360097 0.2828250429158399 3.147239071973947e-05 0.0378187125466048 4.656667989155393e-05 0.0007102815399137 0.0053031795330487 +Fad binding 4 11 2.1553947433355334 0.031130957372532 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0200438347607983 0.1178616319260966 0.0255840399150975 0.0003409473829516 0.0012730265791845 +Transporter activity 50 175 2.150979083056768 0.0314778506986892 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 2.367747986115468e-07 0.0001458723093882 7.905652984158376e-08 2.8112898082797066e-08 1.747254499753895e-07 +Abc type transporter activity 3 7 2.1172970269243176 0.0342346470741325 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.0011653076128861 1.0 0.0016986126979642 0.0028063338575205 0.0062616815035888 +Dicarboxylic acid transmembrane transporter activity 2 7 2.1137198518386 0.0345392019257162 2.842233009708738 7.20873786407767 1.0708946030323223 0.2426579907451208 1.9772646753006824 0.7975212565102757 1.0844681659651012 0.2564515003952125 0.1268321491559422 1.0 0.1432798584585485 0.0061570039439817 0.0397387250697101 +Palmitoyltransferase activity 0 5 2.0856119731383327 0.0370137859049894 1.8786407766990292 5.084951456310679 0.875863834441912 0.3421870647647222 1.2306088543936362 0.6827036113457149 1.018188317250868 0.2997914787323893 0.1487772667192279 1.0 0.1677870330809631 0.3715199079432311 0.6118721898827044 +Organic cation transmembrane transporter activity 1 5 2.0579506504251563 0.0395948708862168 1.9271844660194175 5.04126213592233 1.6158747778246996 0.14183106997637 1.275055237696066 0.9168044752551467 0.8418646651592007 0.1871331589544055 0.0059914484737676 0.001984476440523 0.0077184558590264 0.0435926191526008 0.0277461310389573 +Serine type carboxypeptidase activity 4 5 2.0398568343542443 0.0413645871380068 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0414759377879109 0.0238038053541035 0.0008973897437505 0.0055254488719224 2.639864710894744e-05 +Calcium ion binding 14 76 2.0273318354495538 0.042628487850397 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 0.0844505769005424 0.3860509975104039 0.1278733559720672 0.0072539794291604 0.1903848390974876 +Sulfur compound transmembrane transporter activity 2 8 2.0048145748230937 0.0449828738149056 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0018068608143251 0.1305522111527444 0.0026246094830452 0.0319451393300601 0.0498364179528963 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..41a1cce83c878cdf7fd8a3679fe0c13579361f01 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 1376, + "title": "Average number of proteins per term", + "value": 16.188953488372093 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..59d9a340c91d04b5594b5ecef5d4827b83f63ed1 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..610ffcfcf99f46e21f01403e7a4fbc54731ba11c --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,373 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cholesterol binding 0.8043453449076795 2.8050796041699804 0.0050304154446254 0.9990310719045258 0.4365355574383553 13 O95772,Q9H4L5,P45880,O15118,O75477,Q14108,P08133,P21796,P30536 9 +Tetrapyrrole binding 0.7372036337175806 2.725926253657163 0.0064121323082277 0.9998568336025532 0.4365355574383553 16 Q8WUJ1,Q16850,P30519,O43169,O15173 5 +Sterol binding 0.7255379338534006 2.661834055028786 0.0077716182259321 0.9999782417398112 0.4365355574383553 16 O95772,Q9H4L5,P45880,O15118,O75477,Q14108,P08133,P21796,P30536 9 +Ion transmembrane transporter activity 0.4593192613518108 2.6473888867443227 0.0081116011701878 0.9999864222561444 0.4365355574383553 104 Q70HW3,P00403,Q15043,Q9UDW1,Q8TDW0,P30825,Q93050,P21796,Q6N075,O43772,Q8TAD4,O75964,P00846,Q9UBX3,Q6P4Q7,Q13423,Q9Y666,O15439,Q9HD20,Q9Y6M7,P45880,P08133,P53985,Q99808,P41440,Q9BQT8 26 +Protein transporter activity 0.7527981961791359 2.6260943059636994 0.0086370883955455 0.9999934513746724 0.4365355574383553 14 Q9HD20,Q99595,O60830,Q9NS69 4 +Alcohol binding 0.715283868084865 2.6050972858198107 0.0091848176324793 0.9999969388111472 0.4365355574383553 16 O95772,Q9H4L5,P45880,O15118,O75477,Q14108,P08133,P21796,P30536 9 +Peptide binding 0.5082628460978965 2.601531490949639 0.0092808543966873 0.9999973210489752 0.4365355574383553 72 P52292,P42892,P55786,Q03519,Q9UIQ6,Q14978,Q8WTV0,P40855,P04439,Q9NQX7,Q15392,Q9Y584,O00264,Q92973,Q9UHV9,O14773,O15212,O43813,Q6P179 19 +Threonine type endopeptidase activity 0.855469405791352 2.514368349118331 0.0119245814539405 0.999999932209206 0.4365355574383553 8 P28070,P28072,P49721,P20618,Q99436 5 +Metalloendopeptidase activity 0.7293318701638746 2.5029176928877432 0.012317418538212 0.9999999607775124 0.4365355574383553 14 O75844,Q5JRX3,P22695,P42892,Q10713,P52888 6 +Steroid binding 0.6621074794850443 2.4762362989445337 0.0132775668437721 0.999999989712194 0.4365355574383553 22 O15173,Q9H4L5,O95772,P45880,O15118,O75477,Q14108,O00264,P08133,P21796,P30536 11 +Sphingolipid binding 0.9262559932684142 2.428899068948021 0.0151447477524895 0.9999999992406714 0.4365355574383553 6 P45880,P21796 2 +Organic acid transmembrane transporter activity 0.6425203402332991 2.35506394463138 0.0185195185105728 0.999999999993252 0.4494784108690925 22 P41440,O15439,O14975,P08183,Q9BQT8,P53985,Q9UBX3 7 +Serine hydrolase activity 0.6540000993163062 2.3519458524601338 0.0186754933085191 0.9999999999945776 0.4494784108690925 17 Q4J6C6,Q5JRX3,O75976,O14773,P42785,Q16740,Q9HB40,Q9H3G5 8 +Protein transmembrane transporter activity 0.7444356054921202 2.312909769907419 0.0207276005590548 0.9999999999996958 0.4494784108690925 11 Q99595,O60830,Q9NS69 3 +Amyloid beta binding 0.7441800223169345 2.3116497143887456 0.0207969946135226 0.999999999999724 0.4494784108690925 11 Q9UHV9,Q9NQX7,O15212,O00264,Q8WTV0 5 +Macromolecule transmembrane transporter activity 0.7186745428777296 2.299060343521796 0.0215015129724172 0.9999999999998976 0.4494784108690925 12 Q99595,O60830,Q9NS69,Q9Y584 4 +Inorganic molecular entity transmembrane transporter activity 0.4322890109239996 2.2635841697156205 0.0235997023964054 0.9999999999999948 0.4494784108690925 78 Q13423,Q9Y666,Q8TAD4,P00403,O75964,O15439,P00846,Q9HD20,P45880,Q9UDW1,Q8TDW0,Q93050,P08133,Q6N075,P21796,Q9UBX3,Q6P4Q7 17 +Cation transmembrane transporter activity 0.4614092664313239 2.2527248580652857 0.0242765025885576 0.999999999999998 0.4494784108690925 74 Q9Y619,Q70HW3,P00403,P08195,Q15043,P30825,Q9UDW1,Q93050,O43808,Q96NB2,O43772,O95202,Q8TAD4,O75964,P00846,P35670,Q6P4Q7,P20674,Q13423,Q9Y666,Q9Y487,P06576,Q9HD20,Q9Y6M7,P16615,P08133,P47985,P24539,Q99808,P36543,Q15758,Q9Y5K8,Q9H9B4,Q96QD8 34 +Ceramide binding 0.9591529079293728 2.227243598858849 0.0259309977237618 0.9999999999999998 0.4494784108690925 4 P45880,P21796 2 +Threonine type peptidase activity 0.767746152495986 2.2162004279026815 0.0266777785956915 1.0 0.4494784108690925 9 P28070,P28072,P49721,P20618,Q99436 5 +Lipopolysaccharide binding 0.8667132031735902 2.191452596738593 0.0284190565011708 1.0 0.4494784108690925 6 P28070,Q8WTV0 2 +Fad binding 0.7127683578656439 2.1553947433355334 0.031130957372532 1.0 0.4607821549084724 11 Q15067,O15254,Q15392,O95831 4 +Transporter activity 0.4756839244254251 2.150979083056768 0.0314778506986892 1.0 0.4607821549084724 175 Q99595,O60830,Q70HW3,P00403,Q15043,O14975,Q8TB61,Q9UDW1,Q8TDW0,P30825,Q8IXU6,Q93050,Q9P0J0,Q9Y6M9,P21796,Q7Z3C6,Q6N075,O43772,O15173,Q13428,Q8TAD4,Q9NS69,Q03519,O75964,O96000,O43676,P00846,P08183,Q8WTV0,Q6NT16,P51991,Q9UBX3,P30536,Q6P4Q7,Q13423,Q9H4L5,Q9Y666,O15439,Q9Y584,Q9HD20,Q9Y6M7,P45880,P08133,P53985,P03915,Q99808,P41440,Q9H2V7,O15118,Q9BQT8 50 +Abc type transporter activity 0.8076420640339709 2.1172970269243176 0.0342346470741325 1.0 0.4849585903039342 7 Q9HD20,O15439,P08183 3 +Xenobiotic transmembrane transporter activity 0.9291129545888448 2.1139505577722466 0.0345194904122774 1.0 0.4849585903039342 4 O15439,P08183 2 +Dicarboxylic acid transmembrane transporter activity 0.8068116040163812 2.1137198518385993 0.0345392019257162 1.0 0.4849585903039342 7 Q9UBX3,P41440 2 +Organic cation transmembrane transporter activity 0.8362925473496913 2.0579506504251563 0.0395948708862168 1.0 0.4908337147696788 5 Q70HW3 1 +Serine type carboxypeptidase activity 0.8318641854391268 2.0398568343542443 0.0413645871380068 1.0 0.4912675615191051 5 O75976,Q9HB40,P42785,Q9H3G5 4 +Calcium ion binding 0.4276068029664477 2.0273318354495538 0.042628487850397 1.0 0.4912675615191051 76 Q8IYU8,Q14257,Q9BPX6,P50995,Q15293,P80303,Q66K14,Q96AY3,Q02818,P08133,Q9Y680,Q9NWM8,P20073,O43852 14 +Porin activity 0.9058308968168788 2.025236345081802 0.0428431012952708 1.0 0.4912675615191051 4 P21796 1 +Sulfur compound transmembrane transporter activity 0.741920027649902 2.0048145748230937 0.0449828738149056 1.0 0.4991647933008882 8 Q9UBX3,Q70HW3 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5842940091520297 1.9545453897406184 0.0506367524452837 1.0 0.5350950387639636 29 O15121,Q16850,P30519,Q32P28,Q9BU89 5 +Hormone binding 0.7157936120840762 1.88329495141696 0.0596604072358002 1.0 0.5616353382402658 8 P42892 1 +Serine type exopeptidase activity 0.7538842403809642 1.882843198558018 0.0597216208339277 1.0 0.5616353382402658 7 O75976,O14773,P42785,Q9HB40,Q9H3G5 5 +Ephrin receptor binding 0.7850688291702851 1.8554041778882369 0.0635385312395562 1.0 0.5751909143791405 6 P98172 1 +G protein alpha subunit binding 0.8531149299289404 1.821572584154336 0.0685198639653164 1.0 0.6122294338719179 4 P80303 1 +Atp dependent peptidase activity 0.7773022220404278 1.8142141211174492 0.0696447669664768 1.0 0.6143025599094365 5 Q16740 1 +Amino acid transmembrane transporter activity 0.6609482635259308 1.7940868732706248 0.0727993038956495 1.0 0.6300115859145524 10 Q9Y619,P08195,Q15758,P30825,Q9H9B4,Q96NB2 6 +Copper ion binding 0.6690000297421365 1.7443705863429937 0.0810944905133621 1.0 0.6463225597270634 9 P00403 1 +Neutral amino acid transmembrane transporter activity 0.7508978126020212 1.7033247556548758 0.0885073102871192 1.0 0.6463225597270634 5 P08195,Q15758,Q9H9B4,Q96NB2 4 +Wide pore channel activity 0.7491994372213071 1.6961574365676124 0.089856068695439 1.0 0.6463225597270634 5 P21796 1 +Collagen binding 0.6760048898877893 1.6953186382757703 0.0900149909661371 1.0 0.6463225597270634 8 Q92791,Q32P28 2 +Isocitrate dehydrogenase activity 0.8203923834396181 1.6933575094618514 0.0903874375784066 1.0 0.6463225597270634 4 P48735 1 +Monooxygenase activity 0.6542626540635025 1.6720089630205948 0.0945225546609309 1.0 0.6463225597270634 9 P30519,Q9BU89 2 +Transition metal ion transmembrane transporter activity 0.8142950391645057 1.6693301923998214 0.0950519598061001 1.0 0.6463225597270634 4 Q9HD20,Q15043,Q8TAD4 3 +Amide transmembrane transporter activity 0.7353919133480198 1.6377418155305636 0.1014755637119306 1.0 0.6463225597270634 5 O15439,P41440 2 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.7314115504036987 1.628441642037994 0.103431273934637 1.0 0.6463225597270634 6 Q14004 1 +Peptidase activity 0.3828002764602411 1.626779199744822 0.103784000818446 1.0 0.6463225597270634 106 Q9P275,P28072,Q5JRX3,P42785,Q9H3G5,P42892,Q99436,P55786,P52888,P28070,Q4J6C6,Q96FZ2,O75844,P49721,Q9UIQ6,Q9HB40,P28074,P81605,Q10713,Q8IYS1,Q8TCT9,O75976,Q16740,P22695,Q9HBH5,Q96RU2,Q9HD42,O14773,Q9Y4W6,P20618,Q6P179 31 +Cargo receptor activity 0.6606060849242315 1.6216855670928083 0.1048706906899994 1.0 0.6463225597270634 8 Q08380,O15260,Q8WTV0,Q14108,Q07954 5 +Mirna binding 0.5908626045806805 1.6209443824652066 0.1050295672129382 1.0 0.6463225597270634 12 Q9BWF3,P22626,P67809,P98175,P09651 5 +Calcium dependent phospholipid binding 0.6215069552140323 1.5938392224456264 0.1109720500865032 1.0 0.648774535732712 10 P50995,P20073,P08133 3 +Apolipoprotein binding 0.7938207669729754 1.5883664250659653 0.112203505029178 1.0 0.648774535732712 4 Q8WTV0 1 +Histone kinase activity 0.6536665308209736 1.5883529137664478 0.112206558539226 1.0 0.648774535732712 8 P05771,P17252 2 +L amino acid transmembrane transporter activity 0.6526061783501271 1.583251857581083 0.1133640710321204 1.0 0.6526734800845092 8 Q9Y619,P08195,Q15758,P30825,Q9H9B4 5 +5 3 exonuclease activity 0.6316998245150119 1.560361695210852 0.1186744314454912 1.0 0.668128208946645 9 Q9UQ84,Q8IV08 2 +Antigen binding 0.6463728946981946 1.5532241337532446 0.1203695976052836 1.0 0.668128208946645 8 P04439,Q15392,Q03519 3 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.5558035480129052 1.5374792366976933 0.1241759957988937 1.0 0.668128208946645 14 Q9BY49,Q15392,Q8N8N7 3 +Monocarboxylic acid transmembrane transporter activity 0.7092035954145959 1.5332904768191633 0.1252042999899392 1.0 0.668128208946645 6 O15439,P53985 2 +Iron ion binding 0.5119613094696717 1.5313380331012414 0.1256858703893728 1.0 0.668128208946645 20 P22830,Q16850,Q32P28,Q15800,Q9BU89,O15460,P31350,P13674 8 +Peptide antigen binding 0.7082202958603743 1.5290631797281078 0.1262487821395539 1.0 0.668128208946645 6 P04439,Q15392,Q03519 3 +Organic hydroxy compound transmembrane transporter activity 0.8819105407251495 1.514255821491854 0.1299609687363072 1.0 0.6697613969331789 3 O15439 1 +Structural constituent of nuclear pore 0.510635533858832 1.5106042469809815 0.1308893112797902 1.0 0.6701272154234035 21 Q9BVL2,Q9BW27,Q7Z3B4,P61970,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Demethylase activity 0.6040149721014743 1.5039991141497668 0.1325815948298216 1.0 0.6701272154234035 10 Q16850 1 +Histone threonine kinase activity 0.7712544138163279 1.498682228238328 0.1339560892868998 1.0 0.6701272154234035 4 P17252 1 +Pre mrna intronic binding 0.699699352029888 1.4856470805615818 0.1373724949736923 1.0 0.6701272154234035 5 P22626 1 +Endopeptidase activity 0.4814374686685108 1.4856301782752697 0.1373769681398755 1.0 0.6701272154234035 55 P28072,Q5JRX3,P42892,Q99436,P52888,P28070,Q4J6C6,O75844,P49721,P28074,Q10713,Q8TCT9,Q16740,P22695,Q96RU2,O14773,Q9Y4W6,P20618,Q6P179 19 +Regulatory rna binding 0.5360762294372026 1.4841674397151825 0.1377645054785841 1.0 0.6701272154234035 15 Q9BWF3,P22626,P67809,P98175,P09651 5 +Pre mrna binding 0.5007166502908397 1.483656806343837 0.1378999907485631 1.0 0.6701272154234035 18 Q9BWF3,P22626,Q92879,P62995,Q9NW64,P09651,P17844 7 +Mrna 3 utr au rich region binding 0.5827803154920256 1.4810504564877744 0.1385931285595472 1.0 0.6701272154234035 11 Q13151,Q15717,Q14103,Q92945 4 +Protein lipid complex binding 0.8707331625541526 1.4725445334748477 0.1408738904113271 1.0 0.6777708853356159 3 Q8WTV0 1 +N6 methyladenosine containing rna binding 0.7613317866900144 1.4591223086084042 0.1445314471463308 1.0 0.6881497275894505 4 P22626 1 +Snap receptor activity 0.5278091818112216 1.4344738233599386 0.1514370938982912 1.0 0.7034271333580612 15 P56962,O95249,Q86Y82,Q9P2W9 4 +Modified amino acid transmembrane transporter activity 0.8601215404976803 1.4329015238935203 0.1518859817299636 1.0 0.7034271333580612 3 O15439 1 +Nucleobase containing compound transmembrane transporter activity 0.5375692781704257 1.431143556033687 0.1523890763687152 1.0 0.7034271333580612 14 O15439,P51991,Q99808,P41440 4 +Serine transmembrane transporter activity 0.7506527415143622 1.4164766504154198 0.1566359958271665 1.0 0.7055049441210997 4 Q15758,Q9H9B4,Q96NB2 3 +Nucleotidase activity 0.6502535912745039 1.4158929967251346 0.1568068357074503 1.0 0.7055049441210997 7 Q5TFE4 1 +Oligosaccharyl transferase activity 0.7483681462140992 1.4073451429846542 0.159325069291855 1.0 0.7071977269212664 4 P46977,P04843,Q8TCJ2 3 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7483681462140992 1.4073451429846542 0.159325069291855 1.0 0.7071977269212664 4 P46977,P04843,Q8TCJ2 3 +Protein kinase c activity 0.6782551949725898 1.3936527991371093 0.1634224761777785 1.0 0.7184851418563054 5 P17252 1 +Calcium dependent protein kinase activity 0.6782551949725898 1.3936527991371093 0.1634224761777785 1.0 0.7184851418563054 5 P17252 1 +Organic anion transmembrane transporter activity 0.4976533701483807 1.3471210288126434 0.177941256479148 1.0 0.7557011386274929 32 Q9Y619,Q9H9B4,Q99808,P41440,P08195,O15439,Q15758,Q8TB61,P30825,Q9Y6M7,Q02978,Q9BQT8,P53985,Q9UBX3,Q96NB2,Q96QD8 16 +2 iron 2 sulfur cluster binding 0.5857922628246707 1.3304902755727368 0.183356788244986 1.0 0.7720694670855343 9 P22830,Q6FI81,P21912,P47985 4 +Scavenger receptor activity 0.658469117911559 1.3084911925674545 0.1907067599410936 1.0 0.7853292184380561 5 Q8WTV0,Q14108,Q07954 3 +Pentosyltransferase activity 0.5053347099113635 1.2987998464021626 0.1940126273880438 1.0 0.7871859054856362 15 Q13126 1 +Inorganic anion transmembrane transporter activity 0.4786164439938103 1.2956960347265876 0.1950802280309607 1.0 0.7871859054856362 21 Q9Y666,O15439,Q9UBX3,Q9Y6M7,Q8TDW0,P45880,P21796,Q6N075 8 +Signaling receptor regulator activity 0.4927740415670889 1.2843990805156595 0.1990023545239481 1.0 0.7972752288212701 16 P51858,Q9UMX5,P43490 3 +L ascorbic acid binding 0.651099137710503 1.2818914382092272 0.1998807318072453 1.0 0.7972752288212701 6 Q32P28,P13674 2 +Lipid transporter activity 0.4773366312946328 1.2748936266356647 0.2023468952373208 1.0 0.7984336675012584 22 Q9H4L5,Q9Y255,O15439,O14975,P08183,O15118,Q7Z3C6,P30536 8 +Phosphatidylcholine binding 0.6157317296695166 1.2571321501073307 0.2087057870935189 1.0 0.8089553888469917 7 P21796 1 +Organophosphate ester transmembrane transporter activity 0.521931266949023 1.2392329088818352 0.215259256595212 1.0 0.8227687140972549 12 O15439,Q99808,P41440 3 +Nucleotide transmembrane transporter activity 0.521931266949023 1.2392329088818352 0.215259256595212 1.0 0.8227687140972549 12 O15439,Q99808,P41440 3 +Purine nucleotide transmembrane transporter activity 0.5373642803334513 1.2372869739526928 0.2159805620588293 1.0 0.8229155065752775 11 O15439,Q99808,P41440 3 +Amide binding 0.3522462364067309 1.2230367173776768 0.2213158284644509 1.0 0.824482823095242 105 P52292,P42892,P21796,P55786,Q03519,P35610,Q9UIQ6,Q14978,Q8WTV0,P40855,P04439,Q9NQX7,Q15392,Q9Y584,P45880,Q96AY3,O00264,Q92973,Q9UHV9,P07602,P41440,Q6P179,O14773,O15212,O43813,Q9H3P7,Q9Y680 27 +Fatty acid ligase activity 0.6081492836668299 1.2221534894584771 0.221649588592818 1.0 0.824482823095242 7 Q9UKU0,O14975 2 +Palmitoyl protein hydrolase activity 0.636975192613678 1.2204578417655505 0.2222913618172817 1.0 0.824482823095242 6 Q9NUJ1 1 +Sterol transporter activity 0.607568422968119 1.2194729884456037 0.2226647219945328 1.0 0.824482823095242 7 Q9H4L5,P30536 2 +Heparin binding 0.5313480521348954 1.2048504643403324 0.2282610344457725 1.0 0.824482823095242 11 O14737,P51858 2 +Metal ion transmembrane transporter activity 0.4722916725199654 1.199926988822336 0.2301676971907094 1.0 0.824482823095242 26 O95202,Q9Y666,Q8TAD4,P08195,Q15043,Q9HD20,Q9Y6M7,P16615,Q96QD8,P08133,P35670,Q6P4Q7 12 +Long chain fatty acid coa ligase activity 0.6315895149392913 1.1970219804375084 0.2312979875244918 1.0 0.824482823095242 6 Q9UKU0,O14975 2 +Arachidonate coa ligase activity 0.6315895149392913 1.1970219804375084 0.2312979875244918 1.0 0.824482823095242 6 Q9UKU0,O14975 2 +Guanylate kinase activity 0.6319767953098545 1.194266995442715 0.2323735437087477 1.0 0.824482823095242 5 Q14168,O14936,Q12959 3 +Atpase coupled transmembrane transporter activity 0.462071183625362 1.1840923730087842 0.2363764989412733 1.0 0.824482823095242 21 P36543,Q03519,O15439,P06576,Q9HD20,P08183,P35670,P28288 8 +Procollagen proline dioxygenase activity 0.6898107375760492 1.1728575715965004 0.240852926424917 1.0 0.8285340669017147 4 Q32P28,P13674 2 +Peptidyl proline dioxygenase activity 0.6898107375760492 1.1728575715965004 0.240852926424917 1.0 0.8285340669017147 4 Q32P28,P13674 2 +Protein kinase a regulatory subunit binding 0.5669160658416041 1.1656687337471183 0.243748406140797 1.0 0.8343229026112854 8 O43823,Q9H3P7,P17252,Q9ULX6 4 +Structural constituent of eye lens 0.7866730891616018 1.1584054388303464 0.2466986206822885 1.0 0.8402408466802698 3 P08670 1 +Tap binding 0.6833335605566044 1.1469426183741955 0.2514053371894147 1.0 0.849595710841821 4 Q03519 1 +Active transmembrane transporter activity 0.3662288826035839 1.1442199149860566 0.2525324460278377 1.0 0.849595710841821 74 Q9Y666,P41440,P00403,Q03519,O96000,Q15043,O15439,O43676,P03915,Q9HD20,Q9UDW1,Q9Y6M7,P08183,Q9Y6M9,P53985,Q9UBX3 16 +Peptide alpha n acetyltransferase activity 0.677183489056639 1.1223573543829108 0.2617105290105046 1.0 0.8502580464374474 4 Q86UY6 1 +Epoxide hydrolase activity 0.6141774446496733 1.117564016536725 0.2637532442598553 1.0 0.8502580464374474 5 P07099 1 +Ether hydrolase activity 0.6141774446496733 1.117564016536725 0.2637532442598553 1.0 0.8502580464374474 5 P07099 1 +Protein geranylgeranyltransferase activity 0.6758291130900702 1.1169464042173969 0.2640172418551452 1.0 0.8502580464374474 4 P53609 1 +Molecular transducer activity 0.464836332338318 1.1062868176586682 0.2686023956673533 1.0 0.8502580464374474 35 Q4VCS5,Q6RW13,Q9UNN8,Q15629,Q07954,P30536,Q99523,Q8WTV0,Q14108,Q9Y6I9,O15031,O15118,O43813,P11717,Q08722,P10586,O15173 17 +Atpase coupled cation transmembrane transporter activity 0.481735570672332 1.1028885785957074 0.2700755547586988 1.0 0.8502580464374474 14 P36543,Q9Y5K8,P06576,Q9HD20,P35670 5 +P type transmembrane transporter activity 0.6106791667156654 1.1025065967954248 0.2702414921618759 1.0 0.8502580464374474 5 P16615,P35670 2 +High density lipoprotein particle binding 0.9784735812133069 1.0987261297403317 0.2718875416133355 1.0 0.8502580464374474 2 Q8WTV0 1 +Apolipoprotein a i binding 0.9784735812133069 1.0987261297403317 0.2718875416133355 1.0 0.8502580464374474 2 Q8WTV0 1 +Abc type xenobiotic transporter activity 0.9761904761904756 1.0909496141293684 0.2752950540623333 1.0 0.8502580464374474 2 P08183 1 +Efflux transmembrane transporter activity 0.9761904761904756 1.0909496141293684 0.2752950540623333 1.0 0.8502580464374474 2 P08183 1 +Protein carrier chaperone 0.5095371878872746 1.087220842641219 0.2769392216945208 1.0 0.8502580464374474 11 P62072,P40855 2 +Cis trans isomerase activity 0.4559240584635595 1.0781218900732368 0.2809793639455575 1.0 0.8572674163837853 27 O15121,Q9NWM8,Q96AY3 3 +Proton transmembrane transporter activity 0.4575657252439696 1.052818627853713 0.2924241258168341 1.0 0.8729684490676652 36 Q13423,P00403,P00846,Q9UDW1,Q93050 5 +Lamin binding 0.5426679664801565 1.046551015427348 0.2953067042719715 1.0 0.8730897985650377 8 Q5JTV8,Q14739,P42167,Q9ULX6 4 +Calcium dependent protein binding 0.4338263838492736 1.0388548362125825 0.2988722537265884 1.0 0.8730897985650377 18 P50995,Q9NW64,P08133,Q99816,P31949,P20073,P09525,P04083 8 +Scaffold protein binding 0.4344174376923995 1.026958830804292 0.3044398501680438 1.0 0.8772502773624961 19 P46108,P07602,P17480,P08670,Q9UQB8 5 +L serine transmembrane transporter activity 0.7504078303425786 1.0239092535784255 0.3058781390727361 1.0 0.8772502773624961 3 Q15758,Q9H9B4 2 +Cyclin dependent protein kinase activity 0.5897066067618013 1.0150363385436505 0.3100885058630802 1.0 0.8807766243064864 6 Q14004 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.6482600182607547 1.0071662225726272 0.3138549019658678 1.0 0.8845367319615233 4 Q14534,Q16850 2 +Poly a binding 0.4798306018711366 1.0044020999183003 0.3151848382602482 1.0 0.8845367319615233 12 P31483,Q13310,Q07666,O00571,Q71RC2,Q93062,O14979 7 +Lrr domain binding 0.7448613376835141 1.0034776064125164 0.3156304763031308 1.0 0.8845367319615233 3 Q6P1K2,Q9NY61 2 +Leucine zipper domain binding 0.7448613376835141 1.0034776064125164 0.3156304763031308 1.0 0.8845367319615233 3 Q6P1K2,Q9NY61 2 +Aspartic type peptidase activity 0.7432699358006941 0.9976239004100076 0.3184617670705045 1.0 0.8874724161036525 3 Q8TCT9 1 +5 3 exodeoxyribonuclease activity 0.9474885844748832 0.9938513668389992 0.3202952341168821 1.0 0.8885670774783985 2 Q8IV08 1 +Nad binding 0.4452850184128247 0.9888402781381598 0.3227412940916339 1.0 0.889963969278734 29 O75874,Q13423,P48735,P30837 4 +Peptide transmembrane transporter activity 0.9455316373124568 0.9872815262256904 0.3235046445144975 1.0 0.8901643115235837 2 O15439 1 +Metalloaminopeptidase activity 0.4762156549657786 0.9843118659702424 0.3249621969692575 1.0 0.890733033923702 12 P55786 1 +Carboxypeptidase activity 0.4734663084897236 0.9690483833125146 0.3325210494323025 1.0 0.9037612770276132 12 Q8IYS1,O75976,P42785,Q9HB40,Q9H3G5 5 +Arylesterase activity 0.9393346379647698 0.9665252495259072 0.3337814185953198 1.0 0.9037612770276132 2 Q9HDC9 1 +Transmembrane receptor protein kinase activity 0.7346651134533216 0.9660439497659472 0.3340221895197772 1.0 0.9037612770276132 3 P11717 1 +Transmembrane receptor protein tyrosine kinase activity 0.7346651134533216 0.9660439497659472 0.3340221895197772 1.0 0.9037612770276132 3 P11717 1 +Minor groove of adenine thymine rich dna binding 0.6363522420296921 0.960045114649294 0.3370325097329778 1.0 0.9037612770276132 4 Q03164,Q14103 2 +Proteoglycan binding 0.7328014907513745 0.9592212372819438 0.3374473039031533 1.0 0.9037612770276132 3 P10586 1 +Aldehyde dehydrogenase nad p plus activity 0.5488448434953813 0.9488310379051688 0.3427065532238669 1.0 0.9086015746359168 7 O94788 1 +G protein coupled receptor activity 0.7282396675125975 0.942547553899007 0.3459123765840131 1.0 0.9118303260145632 3 O43813 1 +Hydrolase activity acting on ether bonds 0.5412610098725466 0.9141102772833448 0.3606589027913147 1.0 0.9301713217928664 7 P07099,P34913 2 +Nuclear localization sequence binding 0.4396060559254558 0.90134600110526 0.367404382518083 1.0 0.9301713217928664 15 Q92973,P52292,Q14978 3 +Lysophosphatidic acid phosphatase activity 0.916177429876053 0.8896815245306466 0.3736369172422134 1.0 0.9374914046205024 2 Q9NPH0 1 +Cyclin binding 0.4521826006766544 0.8878357633838954 0.3746291023306751 1.0 0.9374914046205024 13 Q14004,Q9BWF3,Q96JB5 3 +Anion transmembrane transporter activity 0.4264764709750852 0.8817925252331736 0.3778890145484723 1.0 0.9374914046205024 48 Q9Y666,Q99808,P41440,O15439,Q15043,Q9UBX3,Q9Y6M7,P30825,Q8TDW0,P45880,Q9BQT8,P21796,P53985,Q6N075 14 +Glycosaminoglycan binding 0.4280530311554245 0.8812573239979102 0.3781785588651005 1.0 0.9374914046205024 16 P51858,O14737,P08133,P10586 4 +Deoxyribonuclease activity 0.4092282954241688 0.8760056313932355 0.381026972369237 1.0 0.9374914046205024 18 Q9Y3B8,Q8IV08 2 +Exodeoxyribonuclease activity 0.4825594575103599 0.872699660408918 0.3828268028589687 1.0 0.9374914046205024 10 Q9Y3B8,Q8IV08 2 +Macrolide binding 0.5316867518774526 0.8704332060267437 0.3840637065535421 1.0 0.9374914046205024 7 Q96AY3 1 +Fk506 binding 0.5316867518774526 0.8704332060267437 0.3840637065535421 1.0 0.9374914046205024 7 Q96AY3 1 +Structural constituent of postsynapse 0.5543275541234501 0.8627693476905955 0.3882642953606141 1.0 0.9374914046205024 6 P07196,Q16352 2 +Atpase binding 0.423037604634197 0.8510446749501698 0.3947445364514945 1.0 0.942909534557504 27 Q5JTV8,P36543,Q16740,Q9UII2,Q93050,P40855,Q8IZL8 7 +Mitogen activated protein kinase binding 0.5503901075535067 0.8459794500084511 0.3975642083654951 1.0 0.942909534557504 6 Q96JB5 1 +Quaternary ammonium group binding 0.4771055436646769 0.844627779631395 0.3983186937809457 1.0 0.942909534557504 10 P21796 1 +Mrna 3 utr binding 0.4218507760052732 0.8443554337058615 0.3984708181879037 1.0 0.942909534557504 48 Q9BWF3,P22626,P31483,Q14103,P17844,Q92879,Q13151,P35637,Q14011,O95453,Q15717,Q92945,Q71RC2,Q92615,P07910,Q9Y6M1,Q92804,P04637 18 +Exoribonuclease activity producing 5 phosphomonoesters 0.4106235347773947 0.838731471525789 0.4016200136180794 1.0 0.942909534557504 21 Q9NVH0,Q9NQT4,Q13868,O95453,Q9HBH5,Q9Y3B8,Q15024 7 +G protein beta gamma subunit complex binding 0.5484739974174307 0.8378234218458657 0.402129882291268 1.0 0.942909534557504 6 Q14344,P04899,P41208 3 +Fatty acid binding 0.4985706611848566 0.8312461500837013 0.4058345885723664 1.0 0.9464888031789428 8 Q15067 1 +Nf kappab binding 0.4473001624575108 0.824781224088879 0.409495808230965 1.0 0.9515820402938486 12 Q96JB5 1 +Lipase inhibitor activity 0.5998439746746163 0.8173562022853309 0.4137248972339846 1.0 0.9543690130840384 4 P09525 1 +O acyltransferase activity 0.4436672141886598 0.8049415737106805 0.4208533962291283 1.0 0.9594465017049844 12 Q8NCC3,P23786 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.4009816188538871 0.7899339101866798 0.4295663662854112 1.0 0.9594465017049844 20 O94788 1 +Nucleosomal dna binding 0.406577421107513 0.7846680323622572 0.4326482304385126 1.0 0.9594465017049844 23 P84243,P16403,P07305,P10412,Q8TAQ2,P16402,P07910,Q969G3 8 +Proton transporting atp synthase activity rotational mechanism 0.4526916483299504 0.7835335231282757 0.4333138758112151 1.0 0.9594465017049844 11 P00846 1 +Proton channel activity 0.4526916483299504 0.7835335231282757 0.4333138758112151 1.0 0.9594465017049844 11 P00846 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.400907663433413 0.7745862361023415 0.4385841930032232 1.0 0.9594465017049844 21 O94788 1 +Retromer complex binding 0.5298568036683069 0.759943102645894 0.4472885957087311 1.0 0.9738435248341994 5 Q99523,P11717 2 +Phosphotransferase activity phosphate group as acceptor 0.4281773327387784 0.7531890886578041 0.4513362952251694 1.0 0.9764819852882524 13 Q14168,O14936,Q15126,P22392,Q12959 5 +Acylglycerol o acyltransferase activity 0.504671192616356 0.7484907187581926 0.4541642212350916 1.0 0.9764819852882524 7 Q8NCC3 1 +Zinc ion transmembrane transporter activity 0.8714938030006459 0.7454330756683408 0.4560099548548031 1.0 0.9764819852882524 2 Q8TAD4 1 +Manganese ion transmembrane transporter activity 0.8714938030006436 0.7454330756683343 0.4560099548548071 1.0 0.9764819852882524 2 Q9HD20 1 +Insulin like growth factor receptor binding 0.6730831973898688 0.744942261337774 0.4563066253926935 1.0 0.9764819852882524 3 P46108,Q04917 2 +Acid thiol ligase activity 0.4537468346255254 0.7256049614670067 0.4680809786678934 1.0 0.9893693189662388 10 Q9UKU0,O14975 2 +Prenyltransferase activity 0.4967101076531561 0.7130372685732639 0.4758226957116753 1.0 0.9897656304222712 7 P49354,P53609 2 +Mhc protein binding 0.4616450747134894 0.707231558312314 0.4794225899599895 1.0 0.9897656304222712 9 Q03519,P51572 2 +Phosphatidylserine binding 0.4493939860321829 0.7036955944795483 0.4816223644999757 1.0 0.9897656304222712 10 Q8WTV0,P08133 2 +Mhc class i protein binding 0.4701482191569032 0.6950319483567138 0.4870352800777926 1.0 0.992633262210573 8 Q03519,P51572 2 +G protein beta subunit binding 0.6585610203903614 0.6945359252241842 0.4873461793096774 1.0 0.992633262210573 3 Q9UBI6 1 +Phospholipase inhibitor activity 0.6574315374264565 0.6906511391878958 0.4897848018024313 1.0 0.992633262210573 3 P09525 1 +Chromo shadow domain binding 0.5665116323778836 0.6905885944999077 0.4898241170355952 1.0 0.992633262210573 4 P46100 1 +Long chain fatty acid transporter activity 0.5641213174424877 0.681670164418615 0.4954475372732929 1.0 0.9968004435968164 4 O14975 1 +Protein prenyltransferase activity 0.5014129742206607 0.6442777260727729 0.5193953566423848 1.0 0.997155010014646 5 P53609 1 +Hydrolase activity hydrolyzing n glycosyl compounds 0.4801494212536219 0.640209231473995 0.522036581980529 1.0 0.997155010014646 7 P78549,Q16706 2 +O methyltransferase activity 0.4797354125900848 0.63840657829679 0.5232090498712574 1.0 0.997155010014646 7 O60725 1 +Lipid binding 0.3294372829423638 0.6346416218206926 0.5256621758773266 1.0 0.997155010014646 131 O94788,Q15067,A6NIH7,P21796,O15173,P28070,O15254,Q8WTV0,Q8NCC3,P56589,P30536,Q9H4L5,P10809,P45880,O00264,P08133,O95772,P07602,P50995,P20073 20 +Lipoprotein particle receptor activity 0.833659491193725 0.6288163310978228 0.5294693071379779 1.0 0.997155010014646 2 Q8WTV0 1 +Phospholipase binding 0.5494753815311495 0.6276303029066074 0.5302461527966389 1.0 0.997155010014646 4 P20700,P84103 2 +Aromatic amino acid transmembrane transporter activity 0.8307240704500911 0.62002752546043 0.5352396652124267 1.0 0.998429608424778 2 P30825 1 +Atpase activator activity 0.4193653909060993 0.6113760417543136 0.5409506598500182 1.0 0.998429608424778 11 Q5JTV8,O60884,P05026,P54709,Q99615,Q99543,P25685,Q96KC8,P31689,Q8IXB1 10 +Sequence specific single stranded dna binding 0.4519581389833512 0.6097530963852611 0.5420253760852538 1.0 0.998429608424778 8 P22626,P09651 2 +G rich strand telomeric dna binding 0.4928916623695466 0.6070645718693939 0.5438080605223203 1.0 0.9991557923715564 6 P22626,P09651 2 +Protein phosphatase 2a binding 0.4294941927660673 0.6049662776306355 0.5452014035718116 1.0 0.9991557923715564 10 Q8NFC6,P78318,Q86XL3 3 +Growth factor activity 0.4917800004717496 0.6025998686160441 0.5467749077954824 1.0 0.9991557923715564 6 Q9UMX5 1 +Kinase inhibitor activity 0.3661933820524422 0.5991144366461277 0.5490965752379398 1.0 0.9994138723907476 18 Q9Y3B8 1 +Single stranded telomeric dna binding 0.469201097142936 0.592873867005777 0.5532655683773728 1.0 1.0 7 P22626,P09651 2 +Anion cation symporter activity 0.627286463492053 0.5891564037074036 0.5557563594358803 1.0 1.0 3 Q9Y666 1 +Primary active transmembrane transporter activity 0.3852755955239993 0.5837305363739154 0.5594016192210396 1.0 1.0 51 P00403,Q03519,O15439,O43676,Q9HD20,Q9UDW1,P08183,Q9Y6M9,P03915 9 +Aminopeptidase activity 0.384574801932142 0.5798671769259867 0.5620041918003627 1.0 1.0 15 P55786 1 +Zinc ion binding 0.3277424503211283 0.5730624809932057 0.5666023896818659 1.0 1.0 135 O43823,P00813,Q5JRX3,P42892,P55786,P62072,Q8TAD4,Q03164,Q9UIQ6,P53609,Q8N4Q0,Q8NB78,P17252,P05771,Q8NCC3,Q99536,Q9BWF3,Q8N8N7,Q16629,O43813 20 +Sodium ion transmembrane transporter activity 0.4333590586015052 0.5714759551396007 0.5676770548867545 1.0 1.0 9 P08195,Q9Y6M7,Q6P4Q7 3 +Chloride channel regulator activity 0.6212071778140212 0.5692569879988572 0.5691817516455047 1.0 1.0 3 O15400,Q9H4A3 2 +Chloride channel inhibitor activity 0.6212071778140212 0.5692569879988572 0.5691817516455047 1.0 1.0 3 O15400,Q9H4A3 2 +Single stranded dna exodeoxyribonuclease activity 0.4821685203212906 0.5685368790605752 0.5696704714244296 1.0 1.0 5 Q8IV08 1 +Exoribonuclease activity 0.3748709394921146 0.5653902670140916 0.5718083432369367 1.0 1.0 24 Q9NVH0,Q9NQT4,Q13868,O95453,Q9HBH5,Q9Y3B8,Q15024 7 +Rna 7 methylguanosine cap binding 0.437207862633423 0.5421004132960111 0.5877493340280648 1.0 1.0 8 Q53F19 1 +Flavin adenine dinucleotide binding 0.3803189612783355 0.5376433187558345 0.5908233177520423 1.0 1.0 30 Q15392,O15254,P16435,O95831,Q8NB78,Q16134,Q15067,Q14534 8 +Adenyl nucleotide exchange factor activity 0.4543352295384483 0.5298474726202943 0.5962176877022816 1.0 1.0 7 Q9UL15 1 +Atpase regulator activity 0.4543352295384483 0.5298474726202943 0.5962176877022816 1.0 1.0 7 Q9UL15 1 +Histone methyltransferase activity h3 k4 specific 0.4726982502891992 0.527204455137389 0.5980516152000306 1.0 1.0 6 Q03164,Q9UBL3 2 +Poly pyrimidine tract binding 0.384978277779891 0.5204479523232922 0.602751395403125 1.0 1.0 13 P31943 1 +Anion channel activity 0.3894409405197891 0.5188411042943394 0.6038715512952719 1.0 1.0 12 P45880,P21796 2 +Mrna binding 0.3454395462227532 0.5055666307176006 0.6131609120610557 1.0 1.0 167 Q9Y5S9,Q8N684,Q9BX40,Q96PK6,Q08170,Q15717,Q96PU8,Q9BPZ3,Q71RC2,Q93062,Q8WVV9,Q14103,P61978,Q13151,P08621,P67809,Q99729,Q9BWU0,Q07955,O60506,Q92804,P57772,P51991,P52756,Q96AE4,P22626,O75153,Q14011,P34897,Q92945,P12270,Q92615,Q86V81,Q53F19,Q96I24,O75525,Q12972,Q9BWF3,P31483,O43390,P49756,P35637,Q8IY67,Q9UKA9,P62995,P07910,Q9Y6M1,Q96T37,P38159 49 +Protein disulfide isomerase activity 0.419174336303391 0.5055543413058267 0.6131695412541884 1.0 1.0 9 Q96JJ7 1 +L ornithine transmembrane transporter activity 0.7909328114807466 0.5052700457910556 0.6133691785390412 1.0 1.0 2 P30825 1 +Beta 2 microglobulin binding 0.7896281800391334 0.50165821040094 0.6159079651099573 1.0 1.0 2 P04439 1 +Carbohydrate derivative transmembrane transporter activity 0.396278668808488 0.4970871362993529 0.6191276054924555 1.0 1.0 11 Q99808,P41440 2 +Annealing activity 0.4160949376484659 0.4914769599409043 0.6230891439146318 1.0 1.0 9 P46100 1 +Oxidoreduction driven active transmembrane transporter activity 0.3731679288347829 0.4914020954467946 0.6231420824736187 1.0 1.0 30 P00403,O43676,Q9UDW1,Q9Y6M9,P03915 5 +S100 protein binding 0.4251095550725649 0.4878475633314954 0.6256578185916579 1.0 1.0 8 P50995,P16615 2 +Oxidoreductase activity acting on the ch ch group of donors 0.3733283040641037 0.4843249443107048 0.6281552757619342 1.0 1.0 31 Q9BY49,Q15392,O15254,Q8N8N7,Q15067 5 +Sumo transferase activity 0.506201044386421 0.4754258746026296 0.6344834555861225 1.0 1.0 4 Q13263,P49792,O75928 3 +Dna apurinic or apyrimidinic site endonuclease activity 0.5038443083671943 0.4675209554419698 0.6401272029786771 1.0 1.0 4 Q96FZ2 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.5885438286746305 0.4662617512346461 0.6410281532350257 1.0 1.0 3 Q10472 1 +Acetylgalactosaminyltransferase activity 0.5885438286746305 0.4662617512346461 0.6410281532350257 1.0 1.0 3 Q10472 1 +Semaphorin receptor activity 0.7746249184605217 0.4608843063529224 0.6448816117368079 1.0 1.0 2 O15031 1 +Chaperone binding 0.3754019110807863 0.459531468772332 0.645852559349009 1.0 1.0 39 P62072,P10809,O15212,Q13217,P61604,Q14108,Q7L5D6,Q9UL15 8 +Lipid transfer activity 0.4522006258285367 0.455972140456934 0.6484100120498915 1.0 1.0 5 P30536 1 +Box h aca snorna binding 0.500315875831177 0.4557707822267577 0.6485548165869621 1.0 1.0 4 Q14978 1 +Mrna methyltransferase activity 0.4520205010114704 0.4553188224764959 0.6488798868116363 1.0 1.0 5 Q96FX7 1 +Antiporter activity 0.3977119359089492 0.4538329567662691 0.6499490609604262 1.0 1.0 10 Q9UBX3 1 +2 oxoglutarate dependent dioxygenase activity 0.3607916449998916 0.4496788375798587 0.6529420327302433 1.0 1.0 15 Q32P28 1 +Intramolecular oxidoreductase activity transposing c c bonds 0.4497568074989069 0.4471344637224716 0.6547779766755908 1.0 1.0 5 Q13011 1 +Intramembrane lipid transporter activity 0.4328230360165904 0.4417221396304805 0.6586902867159106 1.0 1.0 7 P08183 1 +Camp dependent protein kinase regulator activity 0.577682942671333 0.4336657444745362 0.664531185421547 1.0 1.0 3 P13861 1 +Cytoskeletal anchor activity 0.4473037412614032 0.4311609391445377 0.6663513534218204 1.0 1.0 6 Q9UQB8 1 +14 3 3 protein binding 0.5730673768791243 0.4200907359282617 0.674419170064283 1.0 1.0 3 P85037 1 +Pdz domain binding 0.3688051756813734 0.4175441787353536 0.6762804171137473 1.0 1.0 12 Q96A65,Q15067,Q9UBI6,Q9UQB8 4 +Beta tubulin binding 0.3386687759429118 0.4167877797027057 0.6768336416535019 1.0 1.0 19 P50402,O14737,Q9UBK9,O75381 4 +Cation channel activity 0.3437749874031456 0.4163200996768327 0.6771757865783512 1.0 1.0 21 P00846,O75964 2 +Ubiquinone binding 0.7547292889758537 0.409114416563955 0.6824556969408824 1.0 1.0 2 Q16134 1 +Transcription regulator inhibitor activity 0.4852378567696921 0.4067687657671278 0.6841778291405238 1.0 1.0 4 Q00577 1 +L glutamine transmembrane transporter activity 0.7501630789302017 0.3976265410434806 0.690905493356955 1.0 1.0 2 Q15758 1 +Thiolester hydrolase activity 0.3314561958265781 0.3913746068488847 0.6955203592462507 1.0 1.0 18 Q9NUJ1 1 +Active ion transmembrane transporter activity 0.3653452558034106 0.3909039802919548 0.6958682117578925 1.0 1.0 44 P20674,Q9Y666,P36543,P00403,P08195,O15439,Q15043,P41440,P06576,Q9Y5K8,Q9HD20,Q9UDW1,Q9Y6M7,P16615,Q02978,P47985,P35670 17 +Procollagen proline 4 dioxygenase activity 0.562873126900659 0.3907260304694366 0.6959997558473683 1.0 1.0 3 P13674 1 +Peptidyl proline 4 dioxygenase activity 0.562873126900659 0.3907260304694366 0.6959997558473683 1.0 1.0 3 P13674 1 +Phosphoprotein binding 0.3531893233304186 0.385946166562797 0.6995365384725349 1.0 1.0 28 P46108,O15344,O95104,Q9Y2W1,Q9Y3B8,P11717 6 +Protein tyrosine serine threonine phosphatase activity 0.4785897409106205 0.3858259254667818 0.6996255934129421 1.0 1.0 4 Q99956 1 +Aspartic endopeptidase activity intramembrane cleaving 0.7452707110241232 0.385488402532117 0.6998755972789585 1.0 1.0 2 Q8TCT9 1 +Single stranded dna binding 0.3516894268346827 0.3787365818226929 0.7048834851828443 1.0 1.0 56 Q96AE4,P22626,P10809,Q96FZ2,Q8NFH5,P46100,P67809,Q00577,Q96I24,P20585,P09651 11 +Nadh dehydrogenase activity 0.3396029997530526 0.3780108217947913 0.7054225547984538 1.0 1.0 22 O95831,P03915,O43676,Q9Y6M9 4 +Importin alpha family protein binding 0.4159194619901633 0.3755786386598881 0.7072301738983797 1.0 1.0 7 Q08379 1 +Calcium cation antiporter activity 0.7387475538160393 0.3695843986527231 0.7116921773669445 1.0 1.0 2 P08195 1 +Cation cation antiporter activity 0.7387475538160393 0.3695843986527231 0.7116921773669445 1.0 1.0 2 P08195 1 +Hexosaminidase activity 0.4267921819841661 0.3670485027025234 0.7135828391517389 1.0 1.0 5 P54802 1 +Histone methyltransferase binding 0.4131195176630459 0.364924257307376 0.7151679464490337 1.0 1.0 7 Q96JN0,Q13185,P83916 3 +Metallopeptidase activity 0.3614718740390447 0.3647561448764362 0.7152934441510177 1.0 1.0 40 Q9UIQ6,P22695,P42892,P55786,Q10713 5 +Magnesium ion transmembrane transporter activity 0.7361382909327979 0.3633141491678466 0.7163702249421546 1.0 1.0 2 Q6P4Q7 1 +Tropomyosin binding 0.5507214047856213 0.3568939608380481 0.7211711909031051 1.0 1.0 3 Q9NYL9 1 +Lysophosphatidic acid binding 0.7296151337247134 0.3478715316616472 0.7279366659782622 1.0 1.0 2 O14773 1 +Mitochondrial ribosome binding 0.4543080939947673 0.313160060419665 0.7541590605093245 1.0 1.0 4 Q07021,Q15070,Q92552 3 +Modified amino acid binding 0.3303551992121875 0.3125779330684716 0.7546013454649492 1.0 1.0 23 Q8WTV0,P08133,P41440 3 +Alpha tubulin binding 0.4120109366857078 0.3081886031246633 0.7579388240873175 1.0 1.0 6 P49354 1 +Histone deacetylase binding 0.3390552617465994 0.3034156542733732 0.7615731172455074 1.0 1.0 28 O43823,Q14839,Q9UHI6,Q14103,Q9ULX6,P52292,P62258,P31946,Q96JN0,P45973,P23246,P04637 12 +Vinculin binding 0.4085466631078073 0.2969019788229734 0.7665413453753818 1.0 1.0 6 P46939,P35221 2 +Calmodulin dependent protein phosphatase activity 0.7038486627527645 0.2902633881284985 0.7716147457061255 1.0 1.0 2 P49593 1 +Tat protein binding 0.4445169712793712 0.2857049072648877 0.7751041458495056 1.0 1.0 4 P06748,P31689,Q12824 3 +Molecular function activator activity 0.3386780104711879 0.2813937152571654 0.7784084379603531 1.0 1.0 12 Q5JTV8,O60884,P05026,P54709,Q99615,Q99543,O95433,Q96KC8,P31689,Q8IXB1,P25685 11 +Sh3 domain binding 0.3107181583506407 0.278627958073824 0.7805303546146711 1.0 1.0 18 O75525,P46108,O43813,Q16204 4 +Rna polymerase core enzyme binding 0.3143589402576348 0.2679632468071256 0.7887276092508133 1.0 1.0 17 Q5BKZ1 1 +Protein self association 0.3353181772796071 0.2672545917493404 0.7892731460430924 1.0 1.0 12 Q9Y282,Q9BTV4,P46108,P28288 4 +Translation repressor activity 0.3627647766908774 0.2653290330786407 0.7907560005978289 1.0 1.0 9 P34897,Q00577,Q14011 3 +Single stranded rna binding 0.3439236564036436 0.2647756060594367 0.7911823299435532 1.0 1.0 37 P52597,P31483,Q07666,P23588,Q71RC2,P07910,Q96KR1,Q93062,P09651,P31943,O14979 11 +3 5 exonuclease activity 0.3274370370687278 0.2605692785581108 0.7944246835717861 1.0 1.0 26 Q15024,Q9Y3B8,Q9BQ61,Q13868 4 +Trna cytosine methyltransferase activity 0.6881930854533442 0.258035929261741 0.7963791783557788 1.0 1.0 2 Q08J23 1 +Phospholipid scramblase activity 0.4337384690883837 0.2568105635533507 0.7973250149690858 1.0 1.0 4 Q7Z3C6 1 +Extracellular matrix binding 0.4314621409921646 0.2508930994262996 0.801896759677837 1.0 1.0 4 Q14118,P08865,P05556 3 +Laminin binding 0.4314621409921646 0.2508930994262996 0.801896759677837 1.0 1.0 4 Q14118,P08865,P05556 3 +Sumo ligase activity 0.5060358890701369 0.2447643578167725 0.8066388929126407 1.0 1.0 3 P49792,O75928 2 +Phosphatase inhibitor activity 0.3627642745886171 0.2337462680253157 0.8151819658756727 1.0 1.0 8 Q8NFC6,Q01105 2 +Galactosyltransferase activity 0.4193864229765076 0.2206183149915432 0.8253896391214088 1.0 1.0 4 O60568,Q8NBJ5,Q16880 3 +Passive transmembrane transporter activity 0.3341640538804511 0.2192998642065573 0.8264164676745087 1.0 1.0 35 O75964,P00846,Q8TDW0,P45880,P21796 5 +Protein kinase a binding 0.3038991383414011 0.2178230252501563 0.8275670037330227 1.0 1.0 17 O43823,Q9H3P7,P17252,P13861 4 +Exopeptidase activity 0.3299932259378587 0.2173534402962928 0.827932913054346 1.0 1.0 32 Q9UIQ6,P42785,P55786 3 +Dna binding transcription repressor activity 0.3573987889368716 0.2144708713469646 0.8301798797707018 1.0 1.0 8 P85037 1 +Phosphatidylinositol 3 kinase regulator activity 0.6637312459230142 0.2121055791363031 0.8320246672102793 1.0 1.0 2 O00459 1 +Symporter activity 0.3209718857850082 0.2096043298291986 0.8339764999979136 1.0 1.0 12 Q9Y6M7,Q9Y666,P53985 3 +Structural constituent of synapse 0.3550179652682081 0.2060768042923238 0.8367309173828141 1.0 1.0 8 P07196,Q16352 2 +Single stranded dna endodeoxyribonuclease activity 0.659165035877357 0.2041448825392328 0.8382402815847567 1.0 1.0 2 P49959 1 +Anaphase promoting complex binding 0.658838878016947 0.2035837300414367 0.8386788084199974 1.0 1.0 2 P53350 1 +Growth factor binding 0.3192191028171239 0.202879181799589 0.8392294664167546 1.0 1.0 12 Q92896,Q99523 2 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.6572080887149283 0.2007929342922771 0.8408604880337884 1.0 1.0 2 O95881 1 +Peptide receptor activity 0.6552511415524972 0.1974769410497236 0.8434543245111339 1.0 1.0 2 Q6RW13 1 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3199825475643258 0.1906919299264148 0.848766961659408 1.0 1.0 29 Q9UQ84,Q8IV08,Q13868,Q9Y3B8,Q15024 5 +Calcium channel regulator activity 0.3729434168521272 0.1905177074578723 0.8489034687535599 1.0 1.0 6 P05771,P30626 2 +Solute cation antiporter activity 0.4759887634757773 0.1815446429617458 0.8559400952582572 1.0 1.0 3 P08195 1 +Phosphotransferase activity for other substituted phosphate groups 0.4732691012304168 0.1763421436198769 0.8600251549453912 1.0 1.0 3 Q9NRN7 1 +Calcium dependent protein serine threonine phosphatase activity 0.4708232162666161 0.1717386021547157 0.8636430365281069 1.0 1.0 3 P49593 1 +Rna cap binding 0.31861919344935 0.1671724756086241 0.867234340918086 1.0 1.0 11 Q53F19 1 +Syntaxin binding 0.2919105177399329 0.1642388761011165 0.869543097914709 1.0 1.0 17 Q08379,Q9BVK6,Q9P253,O15400,O95721 5 +Nadp retinol dehydrogenase activity 0.3625541806734346 0.1630847645785996 0.8704516953039965 1.0 1.0 6 Q9Y394,Q9HBH5,Q9BTZ2 3 +Dynein complex binding 0.3420414195174385 0.1621268257330252 0.8712059817730153 1.0 1.0 8 P49454,Q8TD16 2 +Poly a specific ribonuclease activity 0.3511924207775329 0.1569227682703332 0.8753057156757436 1.0 1.0 7 Q6L8Q7,Q9NZN8,O95453,Q9UIV1,Q9HBH5,Q96GM8 6 +Phospholipase a2 inhibitor activity 0.6278538812785268 0.1548465194007539 0.8769423162966568 1.0 1.0 2 P04083 1 +Virion binding 0.6278538812785248 0.1548465194007511 0.876942316296659 1.0 1.0 2 Q99816 1 +Oxidoreductase activity acting on the ch nh2 group of donors 0.6268754076973151 0.1534550866002091 0.8780394064301826 1.0 1.0 2 P00367 1 +Oxidoreductase activity acting on nad p h 0.3176001396814835 0.1527357225523925 0.8786066887393746 1.0 1.0 32 Q13423,O43676,O95831,Q9Y6M9,P03915 5 +Phosphatidylinositol monophosphate phosphatase activity 0.6232876712328665 0.1484302521967115 0.8820032266944826 1.0 1.0 2 Q13614 1 +Protein tyrosine phosphatase activity 0.3212906225253185 0.1469637937546011 0.8831605983560515 1.0 1.0 10 Q99956,P10586 2 +Isomerase activity 0.2895287055100637 0.139485967958536 0.8890661434900757 1.0 1.0 70 P10809,O15121,Q96AY3,Q13011,Q9NWM8 5 +U1 snrna binding 0.3525474945736683 0.1383329213154269 0.8899773081700375 1.0 1.0 6 P08621 1 +Phospholipid transporter activity 0.3263145258686183 0.1368015371872768 0.8911876685689213 1.0 1.0 9 Q7Z3C6,P08183 2 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.6105675146770919 0.1315862025167217 0.8953115994179894 1.0 1.0 2 O60762 1 +Secondary active transmembrane transporter activity 0.2949946228151233 0.1241065903547546 0.9012308801558366 1.0 1.0 24 Q9Y666,P41440,Q9Y6M7,P53985,Q9UBX3 5 +Complement binding 0.4427406199021093 0.1240373779578947 0.9012856802389426 1.0 1.0 3 Q07021,P35232 2 +Opsonin binding 0.4427406199021093 0.1240373779578947 0.9012856802389426 1.0 1.0 3 Q07021,P35232 2 +Histone acetyltransferase binding 0.3730417754569238 0.1230280945553953 0.9020848507212792 1.0 1.0 4 Q9H6U6,P04637,P12004 3 +Signal sequence binding 0.2971590177385604 0.1226594653622149 0.9023767633634632 1.0 1.0 25 P52292,Q14978,Q9Y584,P40855 4 +Phosphatidylglycerol binding 0.6027397260273848 0.1219666523797053 0.9029254285976518 1.0 1.0 2 Q9UJZ1 1 +Cardiolipin binding 0.6027397260273848 0.1219666523797053 0.9029254285976518 1.0 1.0 2 Q9UJZ1 1 +Phosphatase regulator activity 0.2889165413618607 0.1208290539947511 0.9038264369378805 1.0 1.0 22 Q8NFC6,P30154,O14974,Q01105,P78318,Q86XL3,Q12972 7 +Phosphoserine residue binding 0.3351213568154672 0.1172910692853461 0.9066294018607436 1.0 1.0 5 P62258,O95104 2 +Poly purine tract binding 0.2864661580386872 0.1128256847830373 0.9101687548457082 1.0 1.0 15 P31483,Q13310,Q07666,O00571,Q71RC2,Q93062,O14979 7 +Ubiquitination like modification dependent protein binding 0.3307215148547223 0.1086704141256103 0.9134639089562272 1.0 1.0 5 Q16658,Q12888,Q99543,Q9UER7 4 +Transition metal ion binding 0.3211564135711551 0.1051758321166478 0.9162362875195988 1.0 1.0 181 O43823,P00813,P00403,Q5JRX3,Q16850,O60888,P42892,Q9BU89,P55786,P62072,Q8TAD4,Q9UIQ6,P53609,Q8N4Q0,Q8NB78,P17252,P05771,Q8NCC3,Q32P28,Q9BWF3,Q8N8N7,Q16629 22 +Phospholipase c activity 0.5779517286366463 0.0951534143760225 0.9241929719651164 1.0 1.0 2 P30101 1 +Phosphatase activity 0.3158803410561132 0.0832050963827382 0.933688460466557 1.0 1.0 47 P34913,Q9NPH0,Q969T7,Q99956,Q5TFE4,Q10713 6 +Dystroglycan binding 0.3439947780678876 0.0776015435517469 0.9381450145092898 1.0 1.0 4 Q14118,P18206,Q15149 3 +Dopamine receptor binding 0.3117858308847606 0.0753602956156987 0.939928048850044 1.0 1.0 5 Q96QK1,P50570,Q14344,Q9Y5X3 4 +Acidic amino acid transmembrane transporter activity 0.4026101141924965 0.0722046636191109 0.9424390338322512 1.0 1.0 3 Q15758,Q9UJS0 2 +L aspartate transmembrane transporter activity 0.4026101141924965 0.0722046636191109 0.9424390338322512 1.0 1.0 3 Q15758,Q9UJS0 2 +Acetyl coa hydrolase activity 0.4003262642740625 0.0698116320765708 0.9443435887102432 1.0 1.0 3 O14734,Q9Y305 2 +Exonuclease activity 0.3072839630119062 0.0695512492217187 0.9445508404025558 1.0 1.0 37 Q9UQ84,Q8IV08,Q9BQ61,Q13868,Q9Y3B8,Q15024 6 +Phosphoric ester hydrolase activity 0.3041057699806007 0.0656516642273492 0.9476551556968535 1.0 1.0 59 P34913,Q8IV08,Q9NPH0,Q969T7,Q99956,Q5TFE4,Q10713 7 +Eukaryotic initiation factor 4e binding 0.395106035889065 0.0645564888077565 0.9485271293046508 1.0 1.0 3 Q04637,O00571 2 +Pyruvate dehydrogenase activity 0.3039503754489127 0.0633619424231061 0.9494782918756686 1.0 1.0 5 O00330,P08559,P09622,P11177 4 +Oxidoreductase activity acting on ch oh group of donors 0.3063742934588798 0.0632941511490297 0.9495322731336626 1.0 1.0 57 P48735,Q06136,Q8N0U8,O15439,Q8N4Q0,Q8N8N7,O75874 7 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.3309399477806851 0.0610887846201742 0.951288501046098 1.0 1.0 4 P08559,P12694,P11177 3 +Telomerase rna binding 0.2839860935224901 0.0607181388911313 0.9515836855872482 1.0 1.0 11 Q9NY12,P07910 2 +Magnesium ion binding 0.2942066733119509 0.0576579914267211 0.95402105598127 1.0 1.0 64 P34913,P48735,Q9H773,Q969T7,Q9Y3B8,P17252,O75874,Q9NRN7 8 +R smad binding 0.3255921406333828 0.0549968696202702 0.9561409577013356 1.0 1.0 4 P17844 1 +Telomeric dna binding 0.2590565309272497 0.0531687462088365 0.9575974572913544 1.0 1.0 18 Q9NYB0,Q00577,P22626,P09651 4 +P type potassium transmembrane transporter activity 0.5088062622308992 0.0465476311585506 0.9628737710289744 1.0 1.0 2 P05023 1 +Solute sodium symporter activity 0.2906287770860107 0.0452996288725549 0.9638684832531126 1.0 1.0 5 Q9Y6M7 1 +C palmitoyltransferase activity 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Lipase binding 0.49151989562947 0.0393711781336326 0.96859445860362 1.0 1.0 2 P30533 1 +Misfolded protein binding 0.274714428259238 0.0374851392655588 0.9700981889679255 1.0 1.0 11 P48723,Q13217 2 +Protein phosphatase regulator activity 0.2609301343199354 0.0368224176374873 0.9706265994777268 1.0 1.0 20 Q8NFC6,P30154,Q01105,P78318,Q86XL3,Q12972 6 +Neurotrophin receptor binding 0.4791258969341015 0.0351842875007641 0.9719327912321412 1.0 1.0 2 P19174 1 +Neurotrophin trk receptor binding 0.4791258969341015 0.0351842875007641 0.9719327912321412 1.0 1.0 2 P19174 1 +Epidermal growth factor receptor binding 0.2972672660035876 0.0300033645970738 0.9760643698196318 1.0 1.0 7 O95219 1 +Thioesterase binding 0.4579256360078175 0.0296051833155065 0.9763819314390124 1.0 1.0 2 P60953 1 +Double stranded rna adenosine deaminase activity 0.4367253750815295 0.0256681257463351 0.9795220474459252 1.0 1.0 2 P55265 1 +Laminin 1 binding 0.4311806914546569 0.0248610964761522 0.9801657581500144 1.0 1.0 2 Q14118 1 +Gtpase inhibitor activity 0.2913128674069231 0.0244979685697204 0.9804554040764564 1.0 1.0 6 Q13098,O43924,Q13576,O94813,O00410 5 +Pyrophosphate hydrolysis driven proton transmembrane transporter activity 0.2915223070528123 0.0235600203920333 0.9812035623971388 1.0 1.0 8 P06576,P36543 2 +Atpase coupled ion transmembrane transporter activity 0.2915223070528123 0.0235600203920333 0.9812035623971388 1.0 1.0 8 P06576,P36543 2 +Solute proton antiporter activity 0.3147423352902797 0.019021701563627 0.9848237931965348 1.0 1.0 2 O95202 1 +Glucocorticoid receptor binding 0.299086757990865 0.0189341983657574 0.984893598075429 1.0 1.0 2 Q04917 1 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.2819843342036611 0.0185758431590017 0.98517947387771 1.0 1.0 4 Q53GQ0,Q8NBQ5,P51659 3 +Adenylyltransferase activity 0.2627741504294401 0.0164613370313529 0.9868663464851668 1.0 1.0 5 Q8NFF5 1 +D1 dopamine receptor binding 0.311582381729203 0.014894645181033 0.9881162319762656 1.0 1.0 3 Q96QK1,Q9Y5X3 2 +Nucleotide diphosphatase activity 0.268821762675853 0.011619515779986 0.9907291763694588 1.0 1.0 4 Q9BW91 1 +Nedd8 specific protease activity 0.2982055464926597 0.0115261521968094 0.9908036647426904 1.0 1.0 3 Q96FW1,Q9BT78 2 +Metallochaperone activity 0.2446982055464964 0.0047918291620032 0.996176688125215 1.0 1.0 3 O75880,O43819 2 +Copper chaperone activity 0.2446982055464964 0.0047918291620032 0.996176688125215 1.0 1.0 3 O75880,O43819 2 +Kinesin binding 0.2740274116103582 0.002351082287425 0.9981241094698784 1.0 1.0 9 Q96EK5,Q86Y91 2 +Dna n glycosylase activity 0.240287300032652 0.0009236723990093 0.9992630161583862 1.0 1.0 5 P29372,P23396,P78549,P12004 4 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4d71ffd4df4cf5b183d729491d66312dcc1bb80b --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 cyclic amp phosphodiesterase activity", "3 5 cyclic gmp phosphodiesterase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Superoxide generating nadph oxidase activator activity", "Symporter activity", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APC", "APEH", "APEX1", "API5", "APMAP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPIF1", "ATR", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOPC", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JAM3", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFKB2", "NFU1", "NGEF", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM192", "TMEM201", "TMEM30A", "TMEM41B", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPO", "TSR1", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC4", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WTAP", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AASDHPPT", "AATF", "ABCB1", "ABCC4", "ABCD3", "ABHD10", "ACBD3", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSL6", "ADA", "ADAR", "AFG3L2", "AGTRAP", "AHSA1", "AIFM1", "AKAP8", "AKAP8L", "ALDH1A2", "ALDH1B1", "ALYREF", "AMOT", "ANKLE2", "ANXA1", "ANXA11", "ANXA4", "ANXA6", "ANXA7", "APMAP", "ASH2L", "ATG9A", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP5B", "ATP5F1", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7B", "ATPIF1", "ATRX", "BAG5", "BAIAP2", "BCAP31", "BCAS3", "BCKDHA", "BICD2", "BOD1L1", "C1QBP", "CALU", "CASK", "CBX1", "CBX3", "CBX5", "CCDC6", "CD47", "CDC42", "CDK13", "CDK5RAP3", "CELF1", "CENPF", "CETN2", "CHD4", "CHMP1A", "CIAPIN1", "CIRBP", "CLPP", "CLUH", "CNNM4", "CNOT2", "CNOT7", "COLGALT1", "COPS4", "COX2", "COX5A", "CPD", "CPSF7", "CPT2", "CPVL", "CRK", "CTNNA1", "CUTA", "CYB5B", "CYB5D2", "CYP51A1", "DAG1", "DAXX", "DCD", "DCTPP1", "DDX20", "DDX3X", "DDX5", "DEGS1", "DHCR24", "DHRS4", "DHRS7", "DLD", "DLG1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNM2", "DOHH", "DPM1", "DUSP9", "ECE1", "ECH1", "EEFSEC", "EFNB1", "EIF4B", "EIF4G1", "ELAVL1", "EMD", "EPHX1", "EPHX2", "ERAP2", "ERGIC3", "ERLIN1", "ETFDH", "EXD2", "EXO1", "EXOC4", "EXOSC2", "EXOSC5", "EXOSC7", "FECH", "FKBP10", "FKBP14", "FKBP7", "FLAD1", "FNTA", "FOXK1", "FSCN1", "FUBP1", "FUBP3", "FUS", "GALNT1", "GAR1", "GET4", "GLG1", "GLUD1", "GNA13", "GNAI2", "GNG12", "GOLGA2", "GOSR1", "GPS1", "H1F0", "H3-3A*", "HDGF", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-A", "HM13", "HMCES", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPK", "HNRNPLL", "HNRNPR", "HSD17B11", "HSD17B12", "HSD17B4", "HSPA13", "HSPD1", "HSPE1", "ICMT", "IDH1", "IDH2", "IGBP1", "IGF2BP2", "IGF2R", "INA", "IPO5", "IQGAP2", "ITGB1", "ITM2C", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF18B", "KIFBP", "KMT2A", "KPNA2", "LANCL1", "LARP4", "LARP4B", "LBR", "LCOR", "LETM1", "LGALS3BP", "LMNB1", "LNPEP", "LRP1", "LRPAP1", "LRRC8C", "LSM14B", "MAN2A1", "MFSD5", "MICU1", "MICU2", "MID1", "MPG", "MPP2", "MRE11", "MRPS27", "MSH3", "MSMO1", "MTAP", "MTMR2", "NAA40", "NAGLU", "NAMPT", "NCBP3", "ND5", "NDC1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NEFL", "NENF", "NME2", "NNT", "NOLC1", "NPC1", "NPEPPS", "NPM1", "NSUN2", "NT5C3B", "NT5DC1", "NTHL1", "NUCB1", "NUCB2", "NUDT9", "NUP107", "NUP133", "NUP160", "NUP35", "NUP54", "NUP58", "NUP85", "NUP88", "NUP93", "NUTF2", "OSBPL3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC4", "PAIP2", "PARN", "PCNA", "PDCD5", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PECR", "PELP1", "PEX14", "PEX19", "PEX3", "PFDN2", "PFDN6", "PGGT1B", "PGRMC1", "PGRMC2", "PHB", "PIAS2", "PIK3R2", "PITRM1", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMVK", "POR", "PPM1F", "PPP1R12A", "PPP1R8", "PPP2R1B", "PRCP", "PRELID1", "PREPL", "PRKAR2A", "PRKCA", "PRKCB", "PROCR", "PSAP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", 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0.1268321491559422 0.0742352733278267 0.0100519320580488 0.0061570039439817 0.0397387250697101 +Abnormal pupillary function 1 7 2.1964176641285 0.0280620624795848 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.231237178687498 0.1389130578490434 0.2590666885683055 0.1713585638073601 0.4482773855235765 +Hemianopia 2 8 2.183963949424102 0.0289648972210454 2.0776699029126213 7.611650485436893 0.5790308557992101 0.4109966183023263 1.4034584217287485 1.4877037085527185 1.0055409588864108 0.2887898466516661 0.231237178687498 0.1389130578490434 0.0354914601129098 0.0379489226270714 0.1889957663081205 +Chronic fatigue 1 5 2.173947984476314 0.0297090418084897 2.0800970873786406 7.354368932038835 0.6505903571445167 0.3551914870642563 1.248646642239502 1.3902068505046723 1.081635717396615 0.2816956203568134 0.1487772667192279 1.0 0.1677870330809631 0.0757571260003459 0.2348875720984273 +Hypoketotic hypoglycemia 2 7 2.156056219649292 0.0310792755195308 2.3470873786407767 7.560679611650485 1.365087782487965 0.212332843161917 1.4324316558480732 0.6923349575659244 0.8002406012991511 0.2265642620801705 0.0036811661553703 0.0516364610584135 0.0047533286028597 0.001983278822638 0.0140126286640228 +Xerostomia 5 14 2.145746440996137 0.031893213806831 4.225728155339806 15.218446601941748 0.9400183964262208 0.3676147626670514 2.1144482637513415 1.4041718405623504 0.8665256443899695 0.3037909474394171 0.269454491362586 1.0 0.3009165941166509 0.0116952906397438 0.0081853110588452 +Hemiparesis 2 15 2.139042908937857 0.0324321934145357 4.492718446601942 16.453883495145632 0.5632847994166561 0.5250125610456521 2.3039529956499933 2.7457486053720115 0.80325121159606 0.3108877318797908 0.3993300711294241 0.2516504230112798 0.1132051672598368 0.1760149897618766 0.5628623106456782 +Anterior rib cupping 1 5 2.1347987174903627 0.0327774551048078 1.0995145631067962 4.240291262135922 0.7580083586017852 0.4401791439408411 1.122280859436629 0.8606995983858212 0.9577037409012152 0.3293084857529619 0.0019051384851628 0.0006219606051344 0.002465796513642 0.0147480216610697 0.0542215392640632 +Scotoma 3 14 2.120962358426254 0.0339249702239095 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.04460118378424 0.1755724648168266 0.0065760397653667 0.0153023562212604 0.0428945912137629 +Hypoglycemic seizures 2 6 2.10973088808652 0.0348815423678332 2.4854368932038833 6.856796116504855 0.9058299307950756 0.3166741060128459 1.3942606188234674 0.5840745955687526 1.0191247609873073 0.2803355691671325 0.1043280169744231 1.0 0.1180585699575878 0.0033170374819039 0.0225979674873623 +Abnormal larynx physiology 5 13 2.101229668283199 0.035620810231264 3.7694174757281553 14.78640776699029 0.7777362681295714 0.3936810823701626 2.010346212391085 1.51625807571557 0.9784109402665334 0.3028779878197117 0.2632179503957043 1.0 0.2941077913158182 0.0106277501006418 0.0071436537580251 +Toe walking 7 21 2.10007870072486 0.0357219186159316 6.740291262135922 22.805825242718445 1.1386089770349623 0.3130572717722256 3.272869930973316 2.572476621751866 1.068544148592376 0.2998505070337083 0.3514786728450914 0.2183067054048652 0.3896854720293997 0.0341229578056568 0.0029392451780606 +Hypothermia 2 10 2.0925855604256607 0.0363861666614633 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 0.0158597254610659 0.0053672672920639 0.0013262573806951 0.0172025832638257 0.0233101974365333 +Bilateral sensorineural hearing impairment 7 26 2.075836008516164 0.0379091207749986 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.3678335624003773 0.2295798469686227 0.0949012099695084 0.0018183768983854 0.0042301612836837 +Distal peripheral sensory neuropathy 1 5 2.064742754109243 0.0389473469416925 1.4344660194174756 4.679611650485437 0.5764101798236201 0.4022081089263229 1.2299169031488042 0.9421478480744178 1.0445462753474666 0.3013565434873159 0.0966999925589776 0.0561990347849709 0.0056684159955205 0.032628233248221 0.1125747569923622 +Basal ganglia calcification 1 7 2.049658103219721 0.0403978061737055 2.2063106796116503 7.344660194174757 0.7754851929382625 0.4050161590811829 1.490637115556397 1.3943873732460157 0.8989440633592655 0.3080162794814239 0.231237178687498 0.1389130578490434 0.0354914601129098 0.1713585638073601 0.4482773855235765 +Positive romberg sign 2 7 2.039307755747812 0.0414193220817242 2.466019417475728 8.308252427184467 1.0733671875840938 0.3096488241780741 1.4485716699970723 1.6764009803624336 0.8283755892460324 0.2651507773538893 0.1193935721196182 1.0 0.1349531130589082 0.0050923434600555 0.0334620993119388 +Temperature instability 3 8 2.0387498331484672 0.0414750014526494 2.563106796116505 8.077669902912621 0.5786926336202384 0.3539234625201496 1.6976277160735205 1.200237196527885 1.1389671471549596 0.2898062051573807 1.0 1.0 1.0 0.0757571260003459 0.0118865434534573 +Abnormal circulating acetylcarnitine concentration 2 7 2.035258055644483 0.0418249142284994 1.7475728155339805 6.606796116504855 1.2739071869107932 0.2367430781797907 1.3686393682873708 0.7076231425197869 0.8717674578101685 0.2465605045996027 0.0043932683594101 0.0561990347849709 0.0056684159955205 0.0025975272437437 0.018020673376298 +Myoclonic spasms 2 6 2.031114714902625 0.0422433590923863 1.8470873786407769 5.735436893203883 0.4111012021794172 0.4034071629491823 1.317697411431444 1.410916714116348 1.1149340295568837 0.2968871614008488 0.0158597254610659 0.1049896535105009 0.0202898922491691 0.0172025832638257 0.0981468657129251 +Vitiligo 1 7 2.0303660933480177 0.042319340525865 1.75 6.893203883495145 0.5228034908965178 0.4514214081097454 1.549545815072826 0.7902638291080828 0.9503325655279016 0.3007892778972581 0.1701770965395962 0.1006582454154426 0.018640880521655 0.097689242801984 0.2898287915273368 +Fluctuations in consciousness 1 7 2.0274950619844603 0.0426118089407578 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.1487772667192279 0.0875404472016038 0.014058804472369 0.0757571260003459 0.2348875720984273 +Neoplasm of the adrenal cortex 1 5 2.009835603454338 0.0444485912102894 1.9029126213592231 5.502427184466019 0.279284275131131 0.3518731642920829 1.1804603603119783 0.9766665776615882 1.363400785954724 0.3120205744103949 0.1342086162653788 1.0 0.1515272625734178 0.0621585272883563 0.1985866733922443 +Decreased plasma carnitine 2 11 1.9957521039141304 0.0459609125615008 3.1723300970873787 11.83252427184466 0.7810684853101371 0.3882846400262963 2.088319668218202 0.9846444515726572 0.9843631004473848 0.2877502083970994 0.0078149165881974 0.0742352733278267 0.0100519320580488 0.0061570039439817 0.0397387250697101 +Basal ganglia cysts 1 7 1.966757731034684 0.0492111477480716 1.5436893203883495 6.509708737864078 0.6375864218957229 0.3423964855972016 1.553428397761971 0.5418441296142611 1.195152711044975 0.2990830010801169 0.0014367219615376 0.0331691185540615 0.0018609890552042 0.0112385866308786 0.0419919493306108 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d2685566c1cf1ec47adf4ab10f7b775f6f5ad750 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 4552, + "title": "Average number of proteins per term", + "value": 22.780316344463973 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d160e5a3abd686a896706b217b8adf642d8d9b3f --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8afa985117865e88935f0bb74177a78bd38f7604 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1210 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Episodic vomiting 0.7857405265840407 2.635851206179772 0.0083926524376685 1.0 0.9462711105543736 12 P00403,P61978,P00846,P22695,P03915 5 +Abnormal metabolic brain imaging by mrs 0.720709928945623 2.6351670490214514 0.0084095884495831 1.0 0.9462711105543736 16 P00403,P03915 2 +Peripheral demyelination 0.714188951787317 2.5990167608093744 0.0093491208293898 1.0 0.9462711105543736 16 P07602,Q9NR77,P00846,P17480,P03915 5 +Abnormality of skeletal muscle fiber size 0.6689016435601536 2.5446486316377355 0.0109387747392317 1.0 0.9462711105543736 18 P22626,Q9BPX6,O95831,P02545,P09651,Q9BUK6 6 +Decreased activity of mitochondrial complex iv 0.7174039037635425 2.524159395885758 0.0115975329709223 1.0 0.9462711105543736 15 Q9Y2R0,Q70HW3 2 +Postural tremor 0.6649843163353366 2.521212465615094 0.0116951212853499 1.0 0.9462711105543736 18 Q9H6K4,Q9NR77,P35637,P00846,Q14108,P20700,P03915 7 +Abnormal muscle fiber morphology 0.5351298020274934 2.5173476254011464 0.0118242102247569 1.0 0.9462711105543736 67 Q5JTV8,P06753,P00403,Q70HW3,P07196,P61978,O43676,O95831,P00846,Q86U42,Q8NI60,P22626,Q9Y276,P50402,P23786,P02545,P03915,Q9BUK6,O14979,Q9BTV4,Q9BPX6,P35637,Q9H173,Q9Y4W6,P09651 25 +Ragged red muscle fibers 0.6985802062218207 2.5118656225242373 0.0120094809023758 1.0 0.9462711105543736 16 P00403,P00846,O95831,Q70HW3 4 +Amyotrophic lateral sclerosis 0.7135839824144684 2.5033819004720392 0.0123012727201201 1.0 0.9462711105543736 15 P22626,P50995,Q96CV9,P35637,Q92804,Q15165 6 +Fatigable weakness of swallowing muscles 0.746789383224893 2.441869215302265 0.014611438849251 1.0 0.9462711105543736 12 P50995,P35637,Q96CV9,Q92804,Q15165 5 +Demyelinating peripheral neuropathy 0.6683404795921146 2.436185797308642 0.0148430583193241 1.0 0.9462711105543736 17 P00846,O15121,P03915,Q9NR77 4 +Abnormal circulating fatty acid concentration 0.6516225530002391 2.4320323884650317 0.0150143646452181 1.0 0.9462711105543736 19 O75431,P23786,O75381,P56589,O43772 5 +Abnormality of the mitochondrion 0.4308281583310406 2.424019006815779 0.0153498020883295 1.0 0.9462711105543736 92 Q4J6C6,Q86Y39,Q70HW3,P00403,P23786,O96000,P35637,Q16836,O43676,Q9Y584,P03915,P00846,Q8N183,Q9Y6M9,Q9Y2R0,Q9UBX3,O43772,Q96CU9 18 +Fatigable weakness of bulbar muscles 0.7104573264498846 2.402544683264221 0.0162814453244988 1.0 0.9462711105543736 14 P50995,P35637,Q96CV9,Q92804,Q15165,P09651 6 +Bulbar signs 0.7248269228320171 2.401296211003717 0.016337106002165 1.0 0.9462711105543736 13 P07602,P06753,Q92734,P35637,P00846,P03915 6 +Fatigable weakness of respiratory muscles 0.7209247219674378 2.3809793839096445 0.0172666782576467 1.0 0.9462711105543736 13 P50995,P35637,Q96CV9,Q92804,Q15165 5 +Central scotoma 0.746367888715666 2.3224302367235636 0.0202097808151804 1.0 0.9462711105543736 11 P00846,P03915,Q9H061 3 +Slow decrease in visual acuity 0.78810741681946 2.310513855348445 0.020859722360162 1.0 0.9462711105543736 9 P00846,P03915 2 +Lacticaciduria 0.8990118448106402 2.3105055700791444 0.0208601805188091 1.0 0.9462711105543736 5 P00846,P03915,Q9BQT8 3 +Abnormal brain lactate level by mrs 0.7588144345022193 2.274558081751784 0.0229324531362922 1.0 0.9462711105543736 10 P00403 1 +Abnormal csf protein level 0.732204768613606 2.2524051907350735 0.0242966780065461 1.0 0.9462711105543736 11 P07602,Q9NR77,P00403,P20700,P03915 5 +Progressive spasticity 0.6519308466242923 2.246128256597287 0.0246957939100622 1.0 0.9462711105543736 16 P10809,O15121 2 +Symptomatic seizures 0.8354791940526085 2.2363778621236925 0.0253270300148755 1.0 0.9462711105543736 7 Q13423,P53985 2 +Segmental peripheral demyelination remyelination 0.8761541992064362 2.2192737244467406 0.0264681080691948 1.0 0.9462711105543736 5 P00846,Q9NR77 2 +Nasogastric tube feeding in infancy 0.8294980778752397 2.2109277719571523 0.0270408391518237 1.0 0.9462711105543736 7 Q92734,P61978,P07602 3 +Mitochondrial respiratory chain defects 0.8712458074631435 2.1995609591419165 0.0278380596657448 1.0 0.9462711105543736 5 P00846,P03915 2 +Abnormal pupillary function 0.8260958101492548 2.1964176641285 0.0280620624795848 1.0 0.9462711105543736 7 Q9NR77 1 +Hemianopia 0.7810751977527872 2.183963949424102 0.0289648972210454 1.0 0.9462711105543736 8 P00403,P03915 2 +Chronic fatigue 0.8648841836651902 2.173947984476314 0.0297090418084897 1.0 0.9462711105543736 5 Q13423 1 +Hypoketotic hypoglycemia 0.8166615243247999 2.1560562196492916 0.0310792755195308 1.0 0.9462711105543736 7 O43772,P23786 2 +Xerostomia 0.6631322916197021 2.145746440996137 0.031893213806831 1.0 0.9462711105543736 14 P50995,P35637,Q96CV9,Q92804,Q15165 5 +Hemiparesis 0.6480397052570297 2.139042908937857 0.0324321934145357 1.0 0.9462711105543736 15 P00403,P03915 2 +Anterior rib cupping 0.8551947460067093 2.1347987174903627 0.0327774551048078 1.0 0.9462711105543736 5 P00813 1 +Scotoma 0.6586349518879359 2.120962358426254 0.0339249702239095 1.0 0.9462711105543736 14 P00846,P03915,Q9H061 3 +Hypoglycemic seizures 0.8465895875675757 2.10973088808652 0.0348815423678332 1.0 0.9462711105543736 6 Q13423,P53985 2 +Abnormal larynx physiology 0.6680913556224858 2.101229668283199 0.035620810231264 1.0 0.9462711105543736 13 P50995,P35637,Q96CV9,Q92804,Q15165 5 +Toe walking 0.6009070013909376 2.10007870072486 0.0357219186159316 1.0 0.9462711105543736 21 P07602,P50402,P06753,P35637,Q8TD16,O95831,P02545 7 +Hypothermia 0.7211530967867628 2.0925855604256607 0.0363861666614633 1.0 0.9462711105543736 10 P00846,O43772 2 +Centrocecal scotoma 0.9195417847050974 2.0775751823227417 0.0377485039666933 1.0 0.9462711105543736 4 P00846 1 +Bilateral sensorineural hearing impairment 0.6016035172761727 2.075836008516164 0.0379091207749986 1.0 0.9462711105543736 26 Q9NSE4,P07602,P00403,P35637,Q15067,P38159,P03915 7 +Distal peripheral sensory neuropathy 0.8379570279391608 2.064742754109243 0.0389473469416925 1.0 0.9462711105543736 5 P00403 1 +Basal ganglia calcification 0.7919946857909465 2.049658103219721 0.0403978061737055 1.0 0.9462711105543736 7 P00403 1 +Positive romberg sign 0.7896104565909899 2.039307755747812 0.0414193220817242 1.0 0.9462711105543736 7 Q8IV08,P41440 2 +Temperature instability 0.7492770263522904 2.0387498331484672 0.0414750014526494 1.0 0.9462711105543736 8 P20700,P07602,Q2TAA5 3 +Abnormal circulating acetylcarnitine concentration 0.7886783236312428 2.035258055644483 0.0418249142284994 1.0 0.9462711105543736 7 O43772,P23786 2 +Myoclonic spasms 0.8273991121081616 2.031114714902625 0.0422433590923863 1.0 0.9462711105543736 6 P00846,Q10713 2 +Vitiligo 0.7875528670260812 2.0303660933480177 0.042319340525865 1.0 0.9462711105543736 7 P00403 1 +Fluctuations in consciousness 0.7868926265656127 2.0274950619844603 0.0426118089407578 1.0 0.9462711105543736 7 P00403 1 +Mitochondrial inheritance 0.9020909666981576 2.0109132666103458 0.0443346188071429 1.0 0.9462711105543736 4 P00846,P00403 2 +Neoplasm of the adrenal cortex 0.8245348345486045 2.009835603454338 0.0444485912102894 1.0 0.9462711105543736 5 P48735 1 +Decreased plasma carnitine 0.6812298299454687 1.9957521039141304 0.0459609125615008 1.0 0.9462711105543736 11 O43772,P23786 2 +Stuttering 0.8960440029632628 1.9877130226382524 0.0468434378301847 1.0 0.9462711105543736 4 P00403 1 +Abnormality of the distal phalanges of the toes 0.8909921671018319 1.9682915191952048 0.0490345051926492 1.0 0.9462711105543736 4 O75431,Q7LGA3,O75844 3 +Loss of subcutaneous adipose tissue in limbs 0.8909921671018267 1.9682915191951815 0.0490345051926519 1.0 0.9462711105543736 4 O75431,Q03252,O75844 3 +Basal ganglia cysts 0.7729723212533341 1.966757731034684 0.0492111477480716 1.0 0.9462711105543736 7 P00846 1 +Abnormal circulating fatty acid anion concentration 0.6417461714766559 1.9585191329137464 0.050169128209951 1.0 0.9462711105543736 13 O43772,P23786 2 +Psychotic mentation 0.886158189729392 1.949674421836908 0.0512149368334207 1.0 0.9462711105543736 4 P00403 1 +Neck muscle weakness 0.6397182191967644 1.9474474004760312 0.0514811200010925 1.0 0.9462711105543736 13 Q9BTV4,P07602,P06753,P35637,P02545,Q86U42,Q9Y5P6 7 +Widely patent fontanelles and sutures 0.884641299858063 1.943825790417967 0.0519164625814649 1.0 0.9462711105543736 4 P98175,O75844 2 +Thoracic scoliosis 0.6388385879118412 1.9426412167895304 0.0520595232458116 1.0 0.9462711105543736 13 Q9NSE4,O75844,P06753,P02545,O75477 5 +Agenesis of corpus callosum 0.3914151438785636 1.9413592610942851 0.0522147160824328 1.0 0.9462711105543736 80 P00403,P98172,P61978,Q8NAT1,Q8N3U4,Q10713,Q15392,P23786,Q14004,Q7LGA3,Q969G3,Q86XL3,P03915,P48651,Q9BX10,O96028,P46100,O14974,P49454 19 +Sensorimotor neuropathy 0.5818878928431189 1.9401594391006245 0.0523603161896233 1.0 0.9462711105543736 32 P07602,Q9NR77,P00403,O95831,P00846,Q9Y2R0,P03915 7 +Abnormality of facial adipose tissue 0.8830405550855946 1.9376504233487128 0.0526658862337905 1.0 0.9462711105543736 4 Q03252,O75844 2 +Impaired visuospatial constructive cognition 0.7085871571643738 1.9363378917550655 0.0528263308362899 1.0 0.9462711105543736 9 P00403,Q10713 2 +Underdeveloped supraorbital ridges 0.6485769513947114 1.9328065741129612 0.0532600301897769 1.0 0.9462711105543736 12 P98175,P40855,O75381,P56589,Q08J23 5 +Mixed demyelinating and axonal polyneuropathy 0.8047665687234934 1.9284089988224573 0.0538042734029555 1.0 0.9462711105543736 5 P00403,P07196,P03915,P35670 4 +Motor neuron atrophy 0.5739084307646881 1.9268915084063123 0.0539931519811456 1.0 0.9462711105543736 21 P22626,P50995,Q92734,Q96CV9,P35637,Q92804,Q15165 7 +Cupped ribs 0.8008756841048357 1.921380204078076 0.0546837923686915 1.0 0.9462711105543736 6 P00813 1 +Muscle stiffness 0.5734968830160172 1.915487363600944 0.0554303791407038 1.0 0.9462711105543736 22 P00846,Q15392,P07602,P23786 4 +Sensory axonal neuropathy 0.6445726644547274 1.911455186067491 0.0559461105628973 1.0 0.9462711105543736 12 P22626,Q8IV08,O95831,Q15067,P09651 5 +Abnormal visual field test 0.7995500136824085 1.906812840949858 0.0565448279101405 1.0 0.9462711105543736 5 P00846 1 +Upper airway obstruction 0.7992724670580217 1.905662563917888 0.0566939992822141 1.0 0.9462711105543736 5 P02545,Q96HY6,O75844 3 +Thin ribs 0.6318978947711548 1.9046384923405384 0.0568270793815726 1.0 0.9462711105543736 13 O75431,Q32P28,O95831,O75844 4 +Ankylosis 0.7988416006750421 1.903876611357317 0.0569262558380747 1.0 0.9462711105543736 5 P02545,P48651,O75844 3 +Focal segmental glomerulosclerosis 0.5662856886892204 1.8874234240837424 0.0591033969916772 1.0 0.9462711105543736 20 Q8NFH4,O75431,P00403,Q14108,Q14C86,Q8N1F7,P03915,Q12769 8 +Rimmed vacuoles 0.6022356827921309 1.875755067020568 0.0606889205406149 1.0 0.9462711105543736 15 P22626,Q9BTV4,P50402,Q9H173,P02545,Q86U42,P09651,O14979 8 +Retinal telangiectasia 0.7896750076722598 1.8746735248563056 0.0608376512979531 1.0 0.9462711105543736 6 P00846 1 +Abnormal middle phalanx morphology of the hand 0.7516109105420596 1.87280157784249 0.0610957900296991 1.0 0.9462711105543736 7 Q15233,P02545,Q03164 3 +Muscle fiber atrophy 0.5572578337600236 1.8401404852939964 0.0657476148286007 1.0 0.9462711105543736 19 P22626,P50402,P23786,P06753,P61978,P35637,P02545 7 +Increased muscle lipid content 0.7016711202658205 1.8169669937273347 0.0692221674051125 1.0 0.9462711105543736 8 Q8NI60,Q9BUK6,P23786,P06753 4 +Metaphyseal striations 0.777814171479636 1.8163537436075792 0.0693161259914465 1.0 0.9462711105543736 5 P00813 1 +Abnormal cardiac ventricular function 0.5788215350996847 1.81393136307767 0.0696882934794906 1.0 0.9462711105543736 16 Q15233,O75844,P00403,P46100,P03915 5 +Type 1 muscle fiber atrophy 0.737637474909423 1.8108608361487024 0.0701623962899655 1.0 0.9462711105543736 7 P02545,P50402,P61978,P06753 4 +Young adult onset 0.6622216672637853 1.8004933478520428 0.071782773025262 1.0 0.9462711105543736 10 P31483,P07602,Q9H0U3,P02545,O15118,P36551 6 +Multiple lipomas 0.6975852568945969 1.797695454654953 0.0722252821247046 1.0 0.9462711105543736 8 P53680,P03915,Q9BUK6 3 +Blurred vision 0.7724217256422512 1.7937964354636724 0.0728456661103544 1.0 0.9462711105543736 5 P00846 1 +Hemifacial spasm 0.845491675195727 1.791818041506985 0.0731621178576706 1.0 0.9462711105543736 4 Q10713 1 +Slow pupillary light response 0.9546041271693304 1.7836769254819749 0.0744761776905065 1.0 0.9462711105543736 3 Q9NR77 1 +Abnormal pupillary light reflex 0.9546041271693304 1.7836769254819749 0.0744761776905065 1.0 0.9462711105543736 3 Q9NR77 1 +Intestinal pseudo obstruction 0.7314748825710735 1.7834263424401908 0.0745169283004403 1.0 0.9462711105543736 7 P00403,P03915 2 +Neoplasm of the pituitary gland 0.5973216328818268 1.7767179973219671 0.0756146496601652 1.0 0.9462711105543736 14 O75874,P48735 2 +Ventricular preexcitation 0.7288771888669278 1.7718408798151295 0.0764209744792974 1.0 0.9462711105543736 7 P00403,P00846 2 +Hip pain 0.7664697982784741 1.76884719953585 0.0769193775890888 1.0 0.9462711105543736 5 P02545,P22626,O75844 3 +Psychosis 0.5507564863183144 1.7665630033541535 0.0773014415025896 1.0 0.9462711105543736 22 Q5JRX3,P00403,P03915,Q6DKK2 4 +Muscle abnormality related to mitochondrial dysfunction 0.5545481808917535 1.7580751187761394 0.0787347286846766 1.0 0.9462711105543736 35 Q86Y39,P00403,O96000,O43676,P03915,P00846,Q9Y6M9,Q9Y2R0,Q9UBX3,Q9BUK6,Q96CU9 11 +Increased connective tissue 0.7246374379179471 1.7529054340182468 0.0796182407082 1.0 0.9462711105543736 7 P02545,O75431,O95831 3 +Abnormal circulating citrulline concentration 0.761953313425898 1.7498795819243704 0.0801390946145093 1.0 0.9462711105543736 5 P00846 1 +Skin pit 0.6698211126483496 1.7483883836385368 0.0803967980084565 1.0 0.9462711105543736 9 O96028,P61978,P16615,Q8N3U4,Q07954 5 +Decreased circulating iga level 0.6861310264745711 1.7434786314189776 0.0812500437128465 1.0 0.9462711105543736 8 P00813 1 +Abnormal astrocyte morphology 0.5912227079102825 1.7418587852912095 0.0815331573034576 1.0 0.9462711105543736 14 P00846,P48735,O95831 3 +Achilles tendon contracture 0.6317906855544508 1.740155767538232 0.0818316701084409 1.0 0.9462711105543736 11 Q8WXH0,Q9BTV4,P50402,Q8N2K0,Q8TD16,P02545,Q08J23 7 +Osteolysis involving bones of the feet 0.7587476061354049 1.7363985004518314 0.082493397233117 1.0 0.9462711105543736 5 O75431,O75844 2 +Foot acroosteolysis 0.7587476061354049 1.7363985004518314 0.082493397233117 1.0 0.9462711105543736 5 O75431,O75844 2 +Aplasia hypoplasia of the femur 0.6117972628565781 1.7350525189661787 0.0827315032519544 1.0 0.9462711105543736 12 Q96HY6,O95831 2 +Chondrosarcoma 0.9406199021207148 1.732157759828404 0.0832454774906987 1.0 0.9462711105543736 3 P48735,Q92804 2 +Progeroid facial appearance 0.7197962805983535 1.7312441829696752 0.0834082220903238 1.0 0.9462711105543736 7 O75431,Q03252,O75844 3 +Inverted nipples 0.6648046823239463 1.723818549397494 0.0847406048746806 1.0 0.947762244200359 9 Q15067,P56589,P61978,Q2TAA5 4 +Abnormal circulating long chain fatty acid concentration 0.7550652180099375 1.7208943804375774 0.0852699915154941 1.0 0.94851180659255 5 O75381,P56589,P23786 3 +Nephropathy 0.5387039463169325 1.7197020166580796 0.0854866210765032 1.0 0.94851180659255 19 P00403,Q10713 2 +Skin nodule 0.5377197795985666 1.713280023617308 0.0866610356555919 1.0 0.94851180659255 19 P34913,P48735,Q9NSE4,P35637,O75874 5 +Recurrent pancreatitis 0.9353737906982124 1.7127876186590985 0.0867516187585828 1.0 0.94851180659255 3 P00403 1 +Cerebral palsy 0.6264217099585502 1.7120288626507412 0.086891349593386 1.0 0.94851180659255 11 P98175,P48735 2 +Central apnea 0.7150400030910459 1.7099219761083706 0.0872803020534014 1.0 0.948574378301382 7 P07602,Q10713 2 +Concentric hypertrophic cardiomyopathy 0.9322829296886356 1.701364761421637 0.0888745140560587 1.0 0.9504906905482128 3 P00403 1 +Polar cataract 0.9289019431195976 1.688860980264196 0.0912460744201024 1.0 0.9504906905482128 3 P08670 1 +Spondyloepimetaphyseal dysplasia 0.7466491934570624 1.6853875948058878 0.0919138154565772 1.0 0.9504906905482128 5 Q96HY6,O95831 2 +Impaired vibration sensation in the lower limbs 0.5798172848517702 1.67639496794051 0.0936608539281831 1.0 0.9504906905482128 14 P00846,Q9NR77 2 +Sparse lateral eyebrow 0.7418609750734738 1.6729829791174118 0.0943306468391622 1.0 0.9504906905482128 6 Q08J23,Q00577,P61978,Q14696 4 +Periauricular skin pits 0.6704859123710507 1.6689822177436364 0.0951209039789495 1.0 0.9504906905482128 8 O96028,Q8N3U4,P61978 3 +Hypoglycemic coma 0.650158427862821 1.6517754997211276 0.0985803249753136 1.0 0.9504906905482128 9 Q13423,Q16836 2 +Abnormality of the phalanges of the toes 0.5737208145797996 1.6412619100598949 0.1007430592275142 1.0 0.9504906905482128 14 O75431,O75844,Q7LGA3,P98172,P02545 5 +Episodic tachypnea 0.698374381613952 1.6349020581344624 0.1020695809707226 1.0 0.9504906905482128 7 Q10713 1 +Aplasia hypoplasia involving the femoral head and neck 0.6969004556964229 1.628244825045211 0.1034729835686347 1.0 0.9504906905482128 7 Q96HY6,O95831 2 +Abnormal circulating copper concentration 0.7328343237977635 1.6268936647641608 0.103759683725221 1.0 0.9504906905482128 5 Q15904,P35670 2 +Goiter 0.7316477553620715 1.6218579264594184 0.1048337719792842 1.0 0.9504906905482128 5 P48735 1 +Widened cerebral subarachnoid space 0.9078390550955407 1.6107729572264256 0.1072292173369193 1.0 0.9504906905482128 3 P00403 1 +Deep palmar crease 0.5886108659309661 1.608609781802171 0.1077016939879889 1.0 0.9504906905482128 12 O75431,P98175 2 +Fatigue 0.3731010915940183 1.6081182074931235 0.1078092922408395 1.0 0.9504906905482128 79 Q13423,Q4J6C6,P07602,Q70HW3,P50995,Q6UN15,P35637,Q96CV9,P46100,P17252,Q92804,Q15165,P09651 13 +Abnormality of krebs cycle metabolism 0.7266366220022029 1.608037603789833 0.1078269433031207 1.0 0.9504906905482128 6 P00846 1 +Cold induced muscle cramps 0.9065482728286468 1.605977517910518 0.1082788497700171 1.0 0.9504906905482128 3 Q9NR77 1 +Dicarboxylic aciduria 0.5271836360640436 1.5921133070192932 0.1113592476329894 1.0 0.9504906905482128 24 P48735,Q16836,O43772,P23786 4 +Proximal upper limb amyotrophy 0.6887114206600253 1.5911941337875672 0.1115658926698073 1.0 0.9504906905482128 7 P02545,Q9BTV4,O14979,P50402 4 +Abnormality of the musculature of the upper arm 0.6887114206600251 1.5911941337875664 0.1115658926698075 1.0 0.9504906905482128 7 P02545,Q9BTV4,O14979,P50402 4 +Dystrophic toenail 0.7224979293577465 1.5903275194049475 0.1117609986301406 1.0 0.9504906905482128 6 Q969G3,O75844 2 +Macrogyria 0.6878715355962315 1.5873881589667742 0.1124247594531093 1.0 0.9504906905482128 7 Q8NAT1,Q15392 2 +Microcytic anemia 0.6185929789932669 1.5789133131235686 0.1143559419197222 1.0 0.9504906905482128 10 Q9UBX3,P46100 2 +Carcinoid tumor 0.7911585856838294 1.5778091113592796 0.1146094700115059 1.0 0.9504906905482128 4 P46100 1 +Abnormality of subcutaneous fat tissue 0.5515833282914913 1.576988611424451 0.1147981455733941 1.0 0.9504906905482128 15 O75431,P36543,O75844,P41227,P02545,P17252 6 +Peripheral axonal degeneration 0.4465174439974252 1.5767711032533018 0.1148482029573452 1.0 0.9504906905482128 66 P22626,Q8IV08,P07602,Q6DKK2,P00403,P41440,Q92734,Q9BPX6,Q96BR5,P17480,O95831,P00846,P02545,Q9BQT8,Q15067,P03915 16 +Progressive external ophthalmoplegia 0.6173383638904455 1.5724818068505688 0.1158388551778375 1.0 0.9504906905482128 10 P00403 1 +Polyneuropathy 0.5154599919343447 1.5671973879481589 0.1170685608274633 1.0 0.9504906905482128 19 P00846,P03915,O95831 3 +Sensory ataxia 0.7880194708717881 1.5653521726636883 0.1175003561755967 1.0 0.9504906905482128 4 P54802,Q9NR77 2 +Progressive hearing impairment 0.5805594536607592 1.564414831019569 0.1177201799816427 1.0 0.9504906905482128 12 P00403 1 +Narrow nasal ridge 0.7162035050061725 1.563349967524071 0.1179703014149029 1.0 0.9504906905482128 6 O75431,O75844 2 +Abnormality of salivation 0.5234235712249724 1.5617211003483054 0.1183537057844195 1.0 0.9504906905482128 40 Q15233,P55795,Q9NR77,P50995,Q96CV9,P15586,P34897,P35637,P46100,Q92804,Q14739,Q15165,P09651,Q03252 14 +Increased circulating prolactin concentration 0.681634529809166 1.5590911302043158 0.1189748126861405 1.0 0.9504906905482128 7 O00170,Q969G3,Q9BUK6,Q99496 4 +Progressive sensorineural hearing impairment 0.6141367072729239 1.5560554248658809 0.11969491335164 1.0 0.9504906905482128 10 P00403,P03915 2 +Abnormal circulating porphyrin concentration 0.7855249937396778 1.5554471210991128 0.1198396190525732 1.0 0.9504906905482128 4 P22830,P50336 2 +Neurodegeneration 0.5244877953910165 1.5533250159592926 0.1203455067756498 1.0 0.9504906905482128 27 Q6DKK2,P50995,Q96CV9,P35637,Q92804,P17480,Q15165 7 +Dyschromatopsia 0.679820978970673 1.5508521621185047 0.1209371168005097 1.0 0.9504906905482128 7 Q9H6K4,Q9H061,Q9Y4W6 3 +Coronary artery atherosclerosis 0.7840543552256243 1.549604992602262 0.1212363539176304 1.0 0.9504906905482128 4 P34913 1 +Abnormal auditory evoked potentials 0.6455458706640298 1.5492348917355774 0.1213252646765488 1.0 0.9504906905482128 8 P20700,P07602 2 +Abnormal synaptic transmission at the neuromuscular junction 0.522970433294316 1.5488843692144934 0.1214095190723631 1.0 0.9504906905482128 26 P50995,Q92734,P35637,Q96CV9,Q92804,Q15165,P09651 7 +Generalized lipodystrophy 0.890701468189228 1.5470211893595445 0.1218581362227602 1.0 0.9504906905482128 3 O75431,O75844 2 +Abnormal heart rate variability 0.7829236821708695 1.5451121264128935 0.1223191443165989 1.0 0.9504906905482128 4 P07602 1 +Hyperconvex nail 0.6784761102756851 1.5447392938113205 0.1224093362921321 1.0 0.9504906905482128 7 O96028,P42892,Q9Y619,P48651 4 +Coxa vara 0.5765553420042646 1.542384931333426 0.1229800811230781 1.0 0.9504906905482128 12 Q96AY3,O95831 2 +Clonic seizure 0.6766581572079424 1.5364719206374085 0.1244226793749985 1.0 0.9504906905482128 7 P07602 1 +Submucous cleft of soft and hard palate 0.5172630358198006 1.5340858084647255 0.1250085441407287 1.0 0.9504906905482128 23 Q15392,O75844,Q7LGA3,P02545,Q8NAT1,Q08J23,P48651 7 +Wormian bones 0.510101334711756 1.5318100072185463 0.1255693258726167 1.0 0.9504906905482128 19 O75844,O95831,P02545,Q32P28,Q96AY3 5 +Cupped ear 0.5649692891611489 1.5314524163789387 0.1256576180044748 1.0 0.9504906905482128 13 P42892 1 +Subcutaneous nodule 0.5319566251407557 1.5277123366940648 0.1265839757563318 1.0 0.9504906905482128 16 O75874,P48735,P35637,Q9NSE4 4 +Decerebrate rigidity 0.7781892185681588 1.5262876064729114 0.1269382538073475 1.0 0.9504906905482128 4 P07602 1 +Occipital encephalocele 0.7087864407136875 1.5245040932383227 0.1273828351334929 1.0 0.9504906905482128 5 Q10713 1 +Centrally nucleated skeletal muscle fibers 0.6391041975741972 1.518122222729468 0.1289835899097182 1.0 0.9504906905482128 8 P06753,P22626,Q9BPX6 3 +Increased adipose tissue 0.8816592731252395 1.5133187471831095 0.1301987129367341 1.0 0.9504906905482128 3 O75431 1 +Loss of eyelashes 0.8812512946400639 1.5117971749186807 0.1305854683331295 1.0 0.9504906905482128 3 O75844 1 +Respiratory arrest 0.703819431187175 1.510129596984536 0.1310103586820037 1.0 0.9504906905482128 6 O43772 1 +Slender build 0.5705557782442919 1.5093162613409163 0.13121798105004 1.0 0.9504906905482128 12 Q15233,Q9NSD9,P17252,P06753 4 +Pituitary adenoma 0.6037016638129044 1.5023848206481296 0.132997754254128 1.0 0.9504906905482128 10 P48735 1 +Lagopthalmos 0.8787145879440035 1.5023347268975782 0.1330106844127878 1.0 0.9504906905482128 3 O75844 1 +Prominent eyelashes 0.6341603740663302 1.4941966382164429 0.1351242310377149 1.0 0.9504906905482128 8 Q92785,Q969G3,P20700,Q8TAQ2 4 +Abnormal circulating free fatty acid concentration 0.7693204362996825 1.49097717890865 0.1359674865791251 1.0 0.9504906905482128 4 O75431,Q16836 2 +Multiple prenatal fractures 0.6657302322635067 1.486677986181981 0.1370998795490468 1.0 0.9504906905482128 7 Q32P28,Q14696,O75718,P06753 4 +Variable expressivity 0.3571276373287407 1.4863002187860668 0.1371997288820781 1.0 0.9504906905482128 80 Q70HW3,P00403,P06753,Q13868,Q00577,P07196,Q9Y5P6,Q9NR77,O15121,Q8TD16,Q8NI60,Q9Y276,P02545,P03915,Q9H061,Q9BX10,P07602,Q9Y4W6,O95470 19 +Tinnitus 0.5363752609413667 1.4859623734095797 0.1372890737554719 1.0 0.9504906905482128 15 Q9NR28,Q969G3,O95831,Q9NR77 4 +Titubation 0.616602119675559 1.485123403961944 0.137511137424078 1.0 0.9504906905482128 9 Q5JRX3,P20700,P35637,Q5T8D3 4 +Axonal degeneration 0.6969685372467321 1.4806119267205826 0.1387100153474447 1.0 0.9504906905482128 6 Q9BQT8,Q6DKK2 2 +Aplasia hypoplasia involving the pelvis 0.5824840239203213 1.479469464622361 0.1390148865587677 1.0 0.9504906905482128 11 Q96HY6,O95831 2 +Cardiac conduction abnormality 0.515382321418 1.473650962094694 0.1405755924469771 1.0 0.9504906905482128 32 P23786,P00403,P00846,P03915,O43772 5 +Stroke like episode 0.6946250626827174 1.470503228607417 0.141425511902516 1.0 0.9504906905482128 6 P00403 1 +Calvarial hyperostosis 0.6947756931582297 1.4645595461769074 0.1430411258506667 1.0 0.9504906905482128 5 P22626,P09651 2 +Generalized clonic seizure 0.691938498208918 1.4589075931940998 0.144590542944976 1.0 0.9504906905482128 6 P07602 1 +Steroid resistant nephrotic syndrome 0.6922336232073378 1.4536634681981957 0.1460396311865621 1.0 0.9504906905482128 5 Q8N1F7,Q9BW27,Q12769 3 +Mitochondrial myopathy 0.5113396311434469 1.452673072439314 0.1463145468305717 1.0 0.9504906905482128 29 Q86Y39,P00403,O96000,O43676,P00846,Q9Y6M9,P03915,Q9BUK6,Q96CU9 9 +Abnormality of the parathyroid gland 0.503036469634946 1.448479524202497 0.1474829883987847 1.0 0.9504906905482128 22 P48735,P00403,P21964,P03915,O75874,P53680,Q08J23 7 +Fasting hyperinsulinemia 0.7575325231890854 1.4439580353801649 0.1487507800413059 1.0 0.9504906905482128 4 Q16836 1 +Shallow orbits 0.5916987036984052 1.4404164696468025 0.1497496068330437 1.0 0.9504906905482128 10 O75431,P61978,O75844 3 +Talipes calcaneovalgus 0.6886946233677596 1.4384849210211197 0.1502965128754363 1.0 0.9504906905482128 5 Q9NR77 1 +Aplasia hypoplasia involving the skeletal musculature 0.5747019885103347 1.4378922978148068 0.1504646154270423 1.0 0.9504906905482128 11 P06753,Q9NR77,Q9Y487,Q9H173,Q8NAT1 5 +Prenatal maternal abnormality 0.5481505146198847 1.436032854093272 0.1509929927873314 1.0 0.9504906905482128 13 P16435,P02545,Q8TAA9,Q14739,O43772 5 +Thoracic kyphoscoliosis 0.6864553016983892 1.435218954278472 0.1512247140253717 1.0 0.9504906905482128 6 P02545,O75844 2 +Nemaline bodies 0.7549992062898915 1.433841778451541 0.1516174196262323 1.0 0.9504906905482128 4 O43676,P06753 2 +Acanthosis nigricans 0.589842311704084 1.4308118229245732 0.1524841537248802 1.0 0.9504906905482128 10 P28070,O75431 2 +Small placenta 0.8584698729759154 1.4267281619675742 0.1536582648884108 1.0 0.9504906905482128 3 O75844 1 +Thin clavicles 0.8584698729759154 1.4267281619675742 0.1536582648884108 1.0 0.9504906905482128 3 O75844 1 +Short umbilical cord 0.8584698729759154 1.4267281619675742 0.1536582648884108 1.0 0.9504906905482128 3 O75844 1 +Heteronymous hemianopia 0.6858176327593941 1.42613803738837 0.1538285010458124 1.0 0.9504906905482128 5 O00170,Q969G3,Q99496 3 +Adipose tissue loss 0.6047452926951061 1.4257719620306477 0.153934176646439 1.0 0.9504906905482128 9 O75431,Q03252,O75844 3 +Increased sensitivity to ionizing radiation 0.6856962240011399 1.4256168541639986 0.1539789685394961 1.0 0.9504906905482128 5 Q969G3,Q99496 2 +Viral hepatitis 0.6847087111591081 1.4213772324496363 0.1552071217016373 1.0 0.9504906905482128 5 P11717,Q9NWH9,P04637 3 +Subacute progressive viral hepatitis 0.6847087111591081 1.4213772324496363 0.1552071217016373 1.0 0.9504906905482128 5 P11717,Q9NWH9,P04637 3 +Aplasia hypoplasia of the cerebral white matter 0.6038627021323946 1.4213455201378096 0.1552163362129461 1.0 0.9504906905482128 9 P00403 1 +Recurrent paroxysmal headache 0.5875232724983412 1.418806267669308 0.1559555049017509 1.0 0.9504906905482128 10 P00403 1 +Abnormal corpus striatum morphology 0.5142852613540536 1.418316815237635 0.1560982895464326 1.0 0.9504906905482128 16 O95831 1 +Premature graying of hair 0.6182414680853842 1.4168972948133898 0.1565129575526445 1.0 0.9504906905482128 8 Q13126 1 +Upper limb postural tremor 0.8548416133952605 1.4131645911176636 0.1576073351166456 1.0 0.9504906905482128 3 Q9NR77 1 +Primary adrenal insufficiency 0.5240363619470589 1.4117525545258292 0.1580228329719939 1.0 0.9504906905482128 15 Q13423,Q969G3,P40855,O75381,P56589 5 +Lower limb pain 0.6806188335174448 1.4099730841861375 0.1585476306785855 1.0 0.9504906905482128 6 P00846 1 +Gonadal neoplasm 0.4950323266506375 1.4061243210873988 0.1596872115098868 1.0 0.951434799467284 21 O75874,Q13423,P48735,P02545 4 +Wide cranial sutures 0.6468214162352981 1.4001575179893584 0.1614661541297131 1.0 0.9557068563747207 7 P02545,P98175,O75844 3 +Abnormal circulating non proteinogenic amino acid concentration 0.6462930760706628 1.397734113540375 0.162192926130241 1.0 0.9557068563747207 7 P00846 1 +Ketotic hypoglycemia 0.8501513725831712 1.3956267820769164 0.1628269131010267 1.0 0.9557068563747207 3 Q13423 1 +Sensory neuropathy 0.5041215483673063 1.3953057315251232 0.1629236644434937 1.0 0.9557068563747207 31 P22626,Q8IV08,Q9NSE4,P00403,Q92734,O95831,P00846,Q15067,P03915 9 +Abnormality of skull ossification 0.5493388266984967 1.3918544841127296 0.1639664672464078 1.0 0.9561694185616044 12 P02545,Q32P28,P54802,O75844 4 +Upper limb muscle weakness 0.4982286390178272 1.3869713221234985 0.1654505077275891 1.0 0.9561694185616044 25 Q9BTV4,P50336,P50402,Q92734,P00846,P02545,Q9Y6X9,P36551,P07196,Q969G3,Q9Y5P6 11 +Horizontal nystagmus 0.4968162323805439 1.3861618344319095 0.1656974925291501 1.0 0.9561694185616044 24 Q9NSE4,P07602,O95831,P00846,Q9H061 5 +Episodic respiratory distress 0.8474053905478285 1.3853571500390272 0.1659432866132837 1.0 0.9561694185616044 3 P00846 1 +Corneal ulceration 0.6745675631987142 1.377797616555751 0.1682657821220146 1.0 0.956476573587615 5 Q96EK5,O75844 2 +Neoplasm of the parathyroid gland 0.6727891930249416 1.3701483009071185 0.1706406128256956 1.0 0.9587131042254364 5 P48735 1 +Parathyroid adenoma 0.6727891930249416 1.3701483009071185 0.1706406128256956 1.0 0.9587131042254364 5 P48735 1 +Diffuse white matter abnormalities 0.5929252729233311 1.3664026183149585 0.1718126274375073 1.0 0.9603672727667032 9 Q9Y5P6,O14936,P16278 3 +Postaxial polydactyly 0.4829470730802402 1.3659767870420838 0.1719462494079224 1.0 0.9603672727667032 18 O00459,P61978,P98175,P17252,Q14739,Q9Y2V7,Q10713 7 +Perseveration 0.6705776665125306 1.3606331909714608 0.1736296371399257 1.0 0.9604227419208126 5 P35637 1 +Diastema 0.5916862448446836 1.3601687860865352 0.1737765177380061 1.0 0.9604227419208126 9 P46100,P17252 2 +Abnormal renal tubule morphology 0.4897658804641606 1.3589792472822757 0.1741531649211356 1.0 0.9604227419208126 22 P00846,P23786 2 +Ventricular escape rhythm 0.6687138664447714 1.3526120039756573 0.1761796155175345 1.0 0.9604227419208126 5 P02545,P50402 2 +Frontotemporal dementia 0.6045578251087541 1.3501695440489296 0.1769616050210283 1.0 0.9604227419208126 8 P35637,P22626,P09651 3 +Oral aversion 0.5895182851581056 1.349256879083238 0.1772544708705101 1.0 0.9604227419208126 9 P35610,Q8TAQ2,Q92785,Q969G3,O14497 5 +Proximal muscle weakness in upper limbs 0.5234906762047667 1.3486412913600796 0.1774522111207397 1.0 0.9604227419208126 14 Q9BTV4,P50336,P50402,P02545,P07196,Q9Y6X9,Q9Y5P6 7 +Heparan sulfate excretion in urine 0.733581121781563 1.3481852237109204 0.1775988159381498 1.0 0.9604227419208126 4 P54802 1 +Intellectual disability progressive 0.5414681106269038 1.348106872951509 0.1776240111866474 1.0 0.9604227419208126 12 P46100,O95831 2 +Increased cerebral lipofuscin 0.6659429620620144 1.3406834920140709 0.1800232365097929 1.0 0.9683070015494524 5 O14773,P07602,P50897 3 +Phenotypic variability 0.3588749964541166 1.3367810401992484 0.1812941197658648 1.0 0.9683070015494524 103 Q70HW3,P00403,P06753,Q13868,Q00577,P07196,Q9Y5P6,Q9NR77,Q92733,P41227,O15121,Q8TD16,P00846,Q8NI60,Q9Y276,P02545,Q969G3,P03915,Q9H061,O14979,Q9BX10,P07602,P50995,Q9Y4W6,O95470 25 +Proximal tubulopathy 0.4905308722813566 1.3341846782695366 0.182143339629119 1.0 0.9683070015494524 25 Q86Y39,Q8N183,P00403,O96000,O43676,Q9Y6M9,P03915,Q96CU9 8 +Micromelia 0.4840755190871874 1.3324643377598766 0.1827076526744182 1.0 0.9683070015494524 21 O75874,P48735,Q96HY6,Q15392 4 +Pathologic fracture 0.5383309508778082 1.3306484612699618 0.1833047087725556 1.0 0.9683070015494524 12 Q13126,P22626,P09651,Q14108 4 +Limb girdle muscular dystrophy 0.585410334520213 1.3285657810813352 0.1839912677509523 1.0 0.9683070015494524 9 P02545,P09651,O14979,P50402 4 +Oromandibular dystonia 0.7283051323002987 1.3270584267216854 0.1844893561360456 1.0 0.9683070015494524 4 P35637 1 +Atrophy degeneration involving the spinal cord 0.660759296573824 1.3238655333137728 0.1855477068527045 1.0 0.9683070015494524 6 P07196,P20700,Q13217 3 +Protrusio acetabuli 0.8308191361946093 1.323312019514962 0.1857316362023153 1.0 0.9683070015494524 3 Q96AY3 1 +Muscle fiber inclusion bodies 0.5529346421449359 1.321125475947426 0.1864595298028035 1.0 0.9683070015494524 11 P07196,P09651,O43676,P06753 4 +Cystic renal dysplasia 0.8292160890637114 1.317315251036984 0.187732975189977 1.0 0.9710914807554264 3 P23786 1 +Cranial asymmetry 0.725557507674093 1.3160532797292854 0.1881561605455652 1.0 0.9721139888523138 4 O96028,P40855 2 +Limb tremor 0.6592077463263024 1.3116737468994693 0.189630238414638 1.0 0.9739944057287048 5 Q9NR77 1 +Abnormal thyroid morphology 0.4926193711832047 1.3112248036868115 0.1897818247688194 1.0 0.9739944057287048 36 P48735,P00813,P02545,P42892,Q969G3,P20585,O75874 7 +Hypoventilation 0.5345651499312933 1.3096776017984906 0.1903049238462353 1.0 0.9739944057287048 12 P06753,P61978,Q8N183 3 +Abnormal muscle fiber protein expression 0.6268328545714108 1.3082880746657437 0.1907756184317706 1.0 0.974647154995982 7 P02545,Q9BTV4,P50402 3 +Abnormal oral physiology 0.4690699015529117 1.3037546607979402 0.192317245835381 1.0 0.9767226889285224 52 Q15233,P55795,P06753,Q9NR77,P50995,Q6UN15,Q96CV9,P15586,P35637,P46100,Q92804,Q15165,P09651,Q03252 14 +Abnormality of circulating adrenocorticotropin level 0.5484519543000916 1.2970092007775944 0.1946280210603286 1.0 0.9792312174792585 11 Q13423,Q969G3,P46100,P16435 4 +Delayed cranial suture closure 0.4879093513859703 1.293971002356048 0.1956754372103113 1.0 0.9816040599607996 28 O75431,O75844,P36543,P41227,P16435,P02545,Q32P28,P40855,O75381,O75718,Q08J23,P48651 12 +Myositis 0.5929922016535644 1.2936010190216711 0.195803270308525 1.0 0.9816040599607996 8 P28070 1 +Migraine 0.477323570170443 1.2869828792689957 0.1981002556222708 1.0 0.9876805734858454 21 P00403 1 +Type ii lissencephaly 0.6527886775297292 1.2840094513546318 0.1991386484494701 1.0 0.9906875713027192 5 Q8NAT1 1 +Secondary growth hormone deficiency 0.7164234303723416 1.279459187543639 0.2007354027086005 1.0 0.9913136055628587 4 O00170,Q969G3 2 +Left ventricular hypertrophy 0.4761252274362884 1.278905208147995 0.2009304384053232 1.0 0.9913136055628587 21 P00403,O75431,P03915 3 +Ureteral duplication 0.6499548431977145 1.2769165520947334 0.2016317098116673 1.0 0.9915893572420464 6 P02545,O75844,P23786 3 +Limited wrist movement 0.650979887318941 1.2762118922320396 0.2018806258827827 1.0 0.9915893572420464 5 Q9H6K4,O75844 2 +Decreased circulating total igm 0.5894114681789133 1.276061022540155 0.2019339486299158 1.0 0.9915893572420464 8 P00813 1 +Distal lower limb amyotrophy 0.5191715007242326 1.2705927930439185 0.2038735521928982 1.0 0.995940354140836 13 P06753,Q92734,Q9NR77,Q8TD16,P02545,P07196 6 +Chondrocalcinosis 0.6491657861038315 1.2683906667865583 0.2046584729748635 1.0 0.995940354140836 5 P02545,P53680 2 +Increased serum lactate 0.3543792445211674 1.263748240527497 0.2063204043221331 1.0 0.995940354140836 104 Q70HW3,P00403,Q5JRX3,Q9BWD1,Q9P0J0,Q9Y6M9,P35610,O95831,P00846,Q8NI60,O14949,Q9UBX3,Q9Y584,P22695,P03915,Q96CU9,Q5U5X0,Q86Y39,Q8N183 19 +Hypoparathyroidism 0.5090122275187283 1.2635316704602095 0.2063981723047097 1.0 0.995940354140836 14 P21964,P00403,P03915 3 +Oculomotor nerve palsy 0.6480148305533397 1.2634281457193233 0.2064353544445833 1.0 0.995940354140836 5 O00170,Q969G3 2 +Proximal muscle weakness 0.4203559566799378 1.2630740102569018 0.2065625831770532 1.0 0.995940354140836 65 P50336,P06753,Q13126,P07196,Q9Y5P6,Q8TD16,P00846,Q86U42,Q8NI60,P17252,Q5T8D3,Q8NAT1,P35670,P22626,P50402,P02545,Q9Y6X9,Q9BUK6,Q9BTV4,Q9BPX6,Q92734,P35637,Q8NFF5,Q9BQT8,P36551,P09651 26 +Muscle hypertrophy of the lower extremities 0.5573544993052828 1.262010238151364 0.20694510236941 1.0 0.995940354140836 10 P02545,Q8NAT1,Q9NR77 3 +Abnormality of dental color 0.8142436780264817 1.2613211544578835 0.2071931625124516 1.0 0.995940354140836 3 Q6P4Q7 1 +Shoulder girdle muscle weakness 0.5416545092281952 1.260406143983973 0.207522886403048 1.0 0.995940354140836 11 P07602,O14979,P06753 3 +Toxemia of pregnancy 0.6449840174824942 1.255300036245666 0.2093698620216586 1.0 0.995940354140836 6 Q14739,P02545,O43772 3 +Episodic pain 0.5073696551278883 1.2538640021772882 0.2098914412302734 1.0 0.9962730349115796 14 Q13423,P23786 2 +Elbow flexion contracture 0.4768915999493549 1.2500704421743796 0.2112738160691558 1.0 1.0 24 P50402,P37268,Q7LGA3,P23786,P06753,P16435,P02545,Q96AY3,P48651 9 +Reduced forced vital capacity 0.7083489136108212 1.2471054580093626 0.2123588319345275 1.0 1.0 4 Q9BQT8,P06753 2 +Disproportionate short stature 0.4712060452626064 1.245732559370913 0.2128625960312247 1.0 1.0 21 Q15392,Q7LGA3,Q03164,Q14696,Q32P28,O75718,P16278,Q96HY6 8 +Broad phalanx of the toes 0.6419643685400086 1.2421648268153989 0.214175754155264 1.0 1.0 6 Q7LGA3,P98172 2 +Visual field defect 0.4738428001306364 1.240331691398023 0.21485273516727 1.0 1.0 46 Q9H6K4,P00403,P00846,O75381,P56589,P03915,Q9H061 7 +Hypoplasia of the iris 0.706254431564345 1.2387134869203038 0.2154516222362976 1.0 1.0 4 O96028,Q7LGA3 2 +Very long chain fatty acid accumulation 0.6411069628403444 1.2384347667136564 0.2155548960813871 1.0 1.0 6 P56589,P40855,O75381 3 +Hypoplastic fifth fingernail 0.6110274204375526 1.2354334720715632 0.2166692219070285 1.0 1.0 7 Q92785,Q969G3,Q8TAQ2 3 +Hypoplasia of the musculature 0.6413727804322826 1.2347862596958696 0.2169100624226652 1.0 1.0 5 Q9NR77,Q9Y487,P06753 3 +Myopathic facies 0.6387681041854374 1.2282589974901514 0.2193497577446299 1.0 1.0 6 Q00577,Q9BUK6,Q9Y5P6,P06753 4 +Chorioretinal dysplasia 0.6396389637342742 1.2273091191947416 0.2197064294214206 1.0 1.0 5 Q8NAT1 1 +Brisk reflexes 0.4718304640521024 1.226086468391877 0.2201661374235817 1.0 1.0 23 Q5JRX3,P35637,Q8NI60,Q10713 4 +Diffuse mesangial sclerosis 0.4927982830041262 1.2228679648681977 0.22137956995122 1.0 1.0 15 Q8NFH4,P00813,Q14C86,Q8N1F7,Q12769 5 +Rhabdomyolysis 0.5180036153530376 1.2173126406237482 0.2234852866706433 1.0 1.0 12 O43772 1 +Abnormality of the temporomandibular joint 0.8016412922425464 1.2142350540849016 0.2246579781429547 1.0 1.0 3 O75844 1 +Abnormal lacrimal duct morphology 0.6364164533113681 1.213411956019725 0.2249723574557305 1.0 1.0 5 P48651 1 +Abnormal circulating ferritin concentration 0.6040476235272845 1.203223354996098 0.2288898994211039 1.0 1.0 7 Q9Y276,P41440 2 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.6329392293798957 1.202895480465943 0.2290167695141118 1.0 1.0 6 P02545,P50402 2 +Axial muscle weakness 0.697104671759318 1.2020606641921228 0.2293400251887263 1.0 1.0 4 P02545,Q8TD16 2 +Brushfield spots 0.6968945838738 1.2012192891172773 0.2296661489323428 1.0 1.0 4 P56589,O75381 2 +Abnormal neuron morphology 0.4720284345425818 1.1981063490437822 0.2308756174552084 1.0 1.0 26 P22626,P50995,Q92734,Q96CV9,P35637,Q92804,Q15165 7 +Type i diabetes mellitus 0.5140773924003522 1.195394807450007 0.2319328134692511 1.0 1.0 12 P00403 1 +Pulmonary carcinoid tumor 0.796320698516404 1.1943755550252169 0.2323310945895631 1.0 1.0 3 P46100 1 +Nasolacrimal duct obstruction 0.6943234951312713 1.190923437708914 0.2336836425668884 1.0 1.0 4 P48651 1 +Head titubation 0.6289579258288868 1.1855701205031024 0.2357921078786242 1.0 1.0 6 P35637 1 +Abnormality of the brainstem white matter 0.7934611034970454 1.1837080057618348 0.2365286687847667 1.0 1.0 3 Q10713 1 +Decreased calvarial ossification 0.6922907367994606 1.1827848047472544 0.2368944442376916 1.0 1.0 4 P02545,O75844 2 +Fasting hypoglycemia 0.7921632673410461 1.1788680480114353 0.2384507226264642 1.0 1.0 3 O43772 1 +Progressive gait ataxia 0.5407455209619859 1.1753629581769474 0.2398495363561248 1.0 1.0 10 P00846 1 +Epispadias 0.7911908646003194 1.175242375594918 0.2398977612478909 1.0 1.0 3 P48651,P53701 2 +Limb girdle muscle weakness 0.4673449757325604 1.1747933982162362 0.2400773819897148 1.0 1.0 25 P07602,P06753,Q8TD16,Q13126,P02545,O14979,Q9Y5P6 7 +Metatarsus adductus 0.5253848997986958 1.1726883337961878 0.2409208114371219 1.0 1.0 11 Q08J23,Q15392,Q03252 3 +Platyspondyly 0.4732218898989035 1.1720607991847518 0.2411726470182111 1.0 1.0 32 P48735,P00813,O95831,Q32P28,Q96AY3,Q96HY6 6 +Abnormal peripheral myelination 0.4717592905152476 1.1694626525120932 0.2422172800049886 1.0 1.0 30 P07602,Q9NR77,Q92734,P00846,P02545,P17480,P03915 7 +Thickened nuchal skin fold 0.5240647060482433 1.16556712276412 0.2437895069454752 1.0 1.0 11 P56589,P61978,P98172,O75381 4 +Supranuclear gaze palsy 0.4828959043620604 1.1628361024423104 0.244896006351853 1.0 1.0 15 P35637,P07602 2 +Psychomotor deterioration 0.5516699061407793 1.158095481875439 0.2468250735962174 1.0 1.0 9 P07602,P36543,P06865,Q9Y487,Q03164 5 +Widely spaced incisors 0.6231423270889174 1.1561818142782094 0.2476067967553508 1.0 1.0 5 P46100 1 +Limb girdle muscle atrophy 0.4905907525367304 1.155041285075787 0.248073520385919 1.0 1.0 14 Q9BTV4,P06753,P50402,Q14331,P02545,Q9Y6X9,P09651,O14979 8 +Ventricular hypertrophy 0.4707175390194963 1.1541034538670365 0.2484577575459412 1.0 1.0 32 Q15233,O75431,O75844,P00403,P23786,P03915,O43772 7 +Knee flexion contracture 0.4677982566419124 1.1533494826401345 0.2487669674910189 1.0 1.0 28 P48651,P06753,P37268,P23786,Q7LGA3,P36543,Q8TD16,O75477,Q96AY3,Q86XL3,Q9Y5P6 11 +Supernumerary bones of the axial skeleton 0.6844487020311963 1.1514027973502698 0.249566563546058 1.0 1.0 4 Q9Y5S9,O75431 2 +Abducens palsy 0.7845930629217162 1.1506582246731358 0.2498728692091245 1.0 1.0 3 P07602 1 +Symphalangism affecting the phalanges of the hand 0.7845454958026175 1.1504810937262075 0.2499457767918937 1.0 1.0 3 Q15233 1 +Proximal symphalangism 0.7845454958026175 1.1504810937262075 0.2499457767918937 1.0 1.0 3 Q15233 1 +Mania 0.5053053038196114 1.1464183723431074 0.251622084383645 1.0 1.0 12 P00403 1 +Abnormality of the parathyroid morphology 0.6198528020317193 1.1459519202795427 0.2518150464674744 1.0 1.0 6 P48735 1 +Babinski sign 0.3316685369953162 1.1420527413500936 0.2534320975589292 1.0 1.0 88 P10809,P07602,Q6DKK2,Q9NR77,P41440,P35637,O15121,O95831,P00846,Q15067 10 +Vertebral compression fracture 0.4698450613380648 1.141184925948299 0.2537929759004731 1.0 1.0 16 Q14696,Q32P28,Q96AY3,Q14108,O75718,Q96HY6 6 +Abnormal placental size 0.6816918536597829 1.14037759369475 0.254129023566183 1.0 1.0 4 O75844 1 +Global brain atrophy 0.4511847391560962 1.1390481880592844 0.2546830559631163 1.0 1.0 19 P07602 1 +Onion bulb formation 0.5899941831607717 1.1383430942222537 0.2549772459192652 1.0 1.0 7 P07196,P02545,Q9NR77 3 +Abnormal ureter morphology 0.4528493368626973 1.135613017319018 0.2561185584776455 1.0 1.0 20 O14936,P23786,O75844,P41227,Q7LGA3,P02545 6 +Constriction of peripheral visual field 0.4565094370546736 1.13373193367607 0.2569070101958002 1.0 1.0 22 P00846,Q9H061,O75381 3 +Premature rupture of membranes 0.616933687469373 1.1332537508189666 0.2571077077047541 1.0 1.0 6 P02545,O75844 2 +Tongue fasciculations 0.5177422077912097 1.1314636839287704 0.2578599803508912 1.0 1.0 11 Q9BQT8,O95831 2 +Fibrous tissue neoplasm 0.450007532860969 1.1311705149607378 0.2579833294555138 1.0 1.0 19 Q13126,Q15392 2 +Aganglionic megacolon 0.4679979505229013 1.1296451664332368 0.2586257710677144 1.0 1.0 16 Q96EK5,P42892,P46100,Q10713 4 +Generalized muscle weakness 0.465191901990298 1.1286006157405164 0.2590663508387867 1.0 1.0 29 P50995,Q96CV9,P35637,O95831,Q92804,Q15165,P09651 7 +Ovarian neoplasm 0.4573358212235985 1.125295513113567 0.260463830434172 1.0 1.0 17 O75874,P02545,P48735 3 +Mitral valve calcification 0.677804385046452 1.1248383501459776 0.2606575401599575 1.0 1.0 4 O75431,O75844 2 +Cardiac valve calcification 0.677804385046452 1.1248383501459776 0.2606575401599575 1.0 1.0 4 O75431,O75844 2 +Abnormality of the pulmonary veins 0.6147998489371458 1.1239732262758115 0.2610243843349171 1.0 1.0 6 Q15392 1 +Shawl scrotum 0.6145465965967141 1.122871885327789 0.2614919095583645 1.0 1.0 6 P46100 1 +Progressive psychomotor deterioration 0.5576085406546905 1.1199387431604693 0.2627398668659948 1.0 1.0 8 Q10713 1 +Atrophy degeneration affecting the brainstem 0.5155659258932253 1.1197263436139713 0.2628303954222306 1.0 1.0 11 O15121,Q13217 2 +Abnormal mitochondria in muscle tissue 0.4556858590179238 1.116131881353417 0.2643656871777358 1.0 1.0 23 Q86Y39,P00403,O96000,O43676,Q9Y6M9,P03915,Q96CU9 7 +Abnormal shoulder physiology 0.7752293464528184 1.115823812982404 0.2644975585655387 1.0 1.0 3 O75844 1 +Cns demyelination 0.4918270363111878 1.1139135569291705 0.265316272849442 1.0 1.0 13 Q15067,P07602,P40855 3 +Exostoses 0.6745591818517715 1.111873995501644 0.2661923310146297 1.0 1.0 4 P48735 1 +Increased serum pyruvate 0.4649103870321186 1.1096261429544636 0.2671601610169314 1.0 1.0 33 Q86Y39,Q70HW3,Q5JRX3,O96000,O43676,Q9BWD1,O95831,P22695,Q9Y6M9,Q96CU9 10 +Slender long bone 0.4986221724963884 1.1091138040782484 0.267381090607163 1.0 1.0 12 P37268,Q32P28,Q9Y487 3 +High frequency sensorineural hearing impairment 0.6737880836006414 1.1087946179016397 0.267518792821374 1.0 1.0 4 Q9NWM8,O75844 2 +Aplasia hypoplasia of the sternum 0.7723792416091173 1.105235971796481 0.2690573537226073 1.0 1.0 3 P98175 1 +Left ventricular systolic dysfunction 0.6109377560609528 1.1036193502450156 0.2697582936800435 1.0 1.0 5 P02545,P49748,O75844 3 +Dolichocephaly 0.4569626180001476 1.1033824069858942 0.2698611334610352 1.0 1.0 25 Q4J6C6,O96028,Q03164,P61978,P46100,P40855,O75381,P56589 8 +Abnormal circulating pyruvate family amino acid concentration 0.4433187728327825 1.102054795383299 0.2704378502578004 1.0 1.0 18 P22695,O96000,P00846,P03915 4 +Incomplete penetrance 0.4613657205524135 1.1016948601305263 0.2705943522504297 1.0 1.0 29 O43707,Q92733,P50995,O95453,P00846,Q9UBB4,Q9NWH9,P36551,Q969G3,P03915,O14979 11 +Short upper lip 0.671631735511549 1.1001856492751343 0.2712512419544219 1.0 1.0 4 O96028,P46100 2 +Abnormal light and dark adapted electroretinogram 0.5806474342679534 1.095201012759666 0.2734285821108664 1.0 1.0 7 P00846 1 +Abnormal full field electroretinogram 0.5806474342679534 1.095201012759666 0.2734285821108664 1.0 1.0 7 P00846 1 +Somatic mutation 0.4611705515730634 1.0945010394586414 0.273735291737879 1.0 1.0 41 Q01844,Q93052,P00813,Q92733,O00170,P30154,P46100,P11717,Q92804,O75874,P20585 11 +Barrel shaped chest 0.6692387566405581 1.090636317543732 0.2754329424124828 1.0 1.0 4 Q32P28 1 +Cyanosis 0.4415243577386497 1.0900997941042756 0.2756691869989605 1.0 1.0 18 P98175,O43772,O75844 3 +Muscle fibrillation 0.4708848102277509 1.0900372046455888 0.2756967556929461 1.0 1.0 15 Q96CV9,Q9BQT8,O95831 3 +Triangular mouth 0.6077018775380838 1.0896982889536515 0.2758460700967688 1.0 1.0 5 Q10713 1 +Metatarsus valgus 0.6688310666572634 1.08900988416039 0.276149526973942 1.0 1.0 4 Q8NAT1 1 +Recurrent fever 0.4511304374743341 1.0852982746227748 0.2777895698341543 1.0 1.0 17 P28070,P61978,Q9NR77 3 +Decreased circulating igg level 0.4866193788702718 1.0840865916270892 0.2783264073110607 1.0 1.0 13 P00813 1 +Abnormal circulating dicarboxylic acid concentration 0.4595482848255509 1.0820592203144477 0.2792262145218904 1.0 1.0 41 P48735,P55263,O14936,P23786,P37268,P41440,Q16134,P22695,P40855,Q9NSD9 10 +Mottled pigmentation 0.7658794405947904 1.0811195983432071 0.2796439166074866 1.0 1.0 3 O75844 1 +Supraventricular arrhythmia 0.4597500560950652 1.078140539212452 0.2809710425899121 1.0 1.0 16 Q8WXH0,Q9BTV4,P50402,P41227,Q8NFF5,P00846,P02545,P12235 8 +Limb joint contracture 0.3347378857278295 1.076469908172799 0.2817171518835015 1.0 1.0 97 Q5JTV8,P06753,P98172,O75477,P07196,P42892,Q08J23,Q9Y5P6,Q9NR77,O75844,P41227,P37268,Q8TD16,Q8IZA0,O00459,Q15392,P23786,P50402,Q7LGA3,P16435,P02545,Q96AY3,Q86XL3,Q9Y6X9,P48651,Q9BTV4,P36543,P35637 28 +Low plasma citrulline 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 1.0 2 P00846 1 +Vascular tortuosity 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 1.0 2 P00846 1 +Retinal arterial tortuosity 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 1.0 2 P00846 1 +Multiple glomerular cysts 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 1.0 2 P00846 1 +Leber optic atrophy 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 1.0 2 P00846 1 +Optic disc coloboma 0.7628058727569161 1.0697312404029338 0.2847403001415545 1.0 1.0 3 P41227,Q10713 2 +Abnormality of the intrahepatic bile duct 0.7620194596485114 1.066819090133999 0.2860535363976551 1.0 1.0 3 Q10713 1 +Abnormal placenta morphology 0.5739824856915982 1.0644570629515553 0.287121695444509 1.0 1.0 7 P02545,P16278,O75844 3 +Nephrotic syndrome 0.4480464989546491 1.0641494012855717 0.2872610245298013 1.0 1.0 23 P00813,Q14108,Q8N1F7,O95721,Q03252,Q12769 6 +Abnormality of hepatobiliary system physiology 0.3432971545707276 1.0640945272676383 0.2872858798257067 1.0 1.0 77 P22830,Q9NSD9,O43772,P00846,P40855,O75381,P56589,P28288,Q10713,P23786,P22695,Q8N511,P03915,P55263,Q16836,P46100,O15118,Q16625,Q8TCJ2 19 +Limited elbow movement 0.4584811827041962 1.0632672012556723 0.2876607946962468 1.0 1.0 33 Q9H6K4,P50402,P23786,P37268,P06753,Q7LGA3,P16435,P02545,Q8WVM7,Q96AY3,P48651 11 +Neuronal loss in central nervous system 0.4899536832416461 1.0607650766958725 0.2887966770304515 1.0 1.0 12 P35637,P07602 2 +Personality changes 0.4658633964494511 1.0596314503938042 0.2893122997659607 1.0 1.0 15 P00403 1 +Aplasia hypoplasia involving the nose 0.4489902085282081 1.0591735481554234 0.2895207494166771 1.0 1.0 24 O75431,P55795,O75844,P61978,P02545,Q00577,Q8N3U4,Q08J23 8 +Neoplasm of fatty tissue 0.5041326404952915 1.0580990382738216 0.2900102928387418 1.0 1.0 11 Q8TAA9,P53680,P03915,Q9BUK6 4 +Optic neuropathy 0.4483740959648359 1.0549644167044845 0.2914415991113028 1.0 1.0 24 Q86Y39,Q8N183,O96000,O43676,P00846,Q9Y6M9,P03915,Q96CU9 8 +Contractures of the joints of the upper limbs 0.3957787225793421 1.0541184093450071 0.291828708733155 1.0 1.0 66 Q9Y619,P06753,P98172,P07196,P42892,O75844,Q9NR77,P41227,P37268,Q8IZA0,Q15392,P50402,P23786,Q7LGA3,P16435,P02545,Q96AY3,Q9Y6X9,P48651,Q9BTV4,P35637,Q99567 22 +Abnormality of the musculature of the thigh 0.5431326541291659 1.0488322797004783 0.2942553179821545 1.0 1.0 8 P02545,Q9BTV4,O14979,P50402 4 +Alveolar ridge overgrowth 0.963470319634702 1.0477571248666573 0.2947505209538503 1.0 1.0 2 Q15392 1 +Tubulointerstitial nephritis 0.5978286736020693 1.047277378890307 0.2949716660875785 1.0 1.0 5 P23786 1 +Sepsis 0.448547040091234 1.0455683157388205 0.2957603841376253 1.0 1.0 25 P00813 1 +Mental deterioration 0.3249323651281723 1.036994616816899 0.299738365963478 1.0 1.0 89 P00403,P21964,P54802,Q14108,P16278,Q03164,P00846,Q9UBB4,Q96F07,P35670,Q10713,P22626,P03915,P07602,P36543,P35637,O15118,P17480,P20700,P09651,O95470 21 +Ethylmalonic aciduria 0.5949123218236206 1.034765764325266 0.3007783149423315 1.0 1.0 5 Q16134 1 +Abnormal circulating iga level 0.4773935406639773 1.0313046917379505 0.3023979588695387 1.0 1.0 13 P00813 1 +Multiple enchondromatosis 0.5934387796798777 1.0312066240751925 0.302443934993073 1.0 1.0 6 O75874,P48735 2 +Abnormal cartilage morphology 0.499121221047433 1.0311180703030265 0.3024854548053195 1.0 1.0 11 O75874,Q7LGA3,P48735 3 +Hand muscle weakness 0.4989157122595721 1.0300121936475677 0.3030042815788003 1.0 1.0 11 P07196,Q8TD16,Q9Y6X9,Q9NR77 4 +Pulmonary hypoplasia 0.4402301102447768 1.0235183860780444 0.3060628112584289 1.0 1.0 22 O75844,P41227,O96000,Q16134,P02545,Q8TAA9,P98175,Q14739 8 +Increased intramyocellular lipid droplets 0.5903329283025804 1.017748960087693 0.3087972733800943 1.0 1.0 6 Q8NI60,Q9BUK6 2 +Generalized hyperkeratosis 0.6497891475315805 1.013232580896651 0.3109490816196261 1.0 1.0 4 P02545,O75844 2 +Respiratory failure 0.4066249858384443 1.0107549570270569 0.3121337263725841 1.0 1.0 62 Q5U5X0,P07602,P06753,Q70HW3,P23786,Q8N183,Q96CV9,P50995,Q92734,P35637,Q92804,Q9NSD9,Q15165,P09651 14 +Dysdiadochokinesis 0.4734010676478653 1.0084968774633816 0.3132159860037795 1.0 1.0 13 Q6DKK2,P41440,Q9Y4W6,P20700,Q9BUK6 5 +Ocular pain 0.6484986945169606 1.0081128864317468 0.3134002719261008 1.0 1.0 4 O75533,Q15043,Q99496 3 +Action tremor 0.4342261673038834 1.0057318043416117 0.314544599725552 1.0 1.0 52 Q15233,Q9H6K4,P07602,Q9NR77,Q5JRX3,P41440,O14773,P35637,Q9Y4W6,P00846,Q9UBB4,Q14108,P20700,P03915 14 +Decreased circulating cortisol level 0.534299306765941 1.0054920539364316 0.3146599737659035 1.0 1.0 8 Q13423,Q969G3 2 +Abnormal chorioretinal morphology 0.444128420959695 1.005368187596314 0.3147195923217585 1.0 1.0 26 P04439,Q9Y619,O14936,P53701,P41227,O60826,Q8NAT1,P40855,O75381,P56589,Q10713 11 +Redundant neck skin 0.560839319590948 1.0039189810041047 0.3154176667936348 1.0 1.0 7 O96000,Q9Y487,P36543 3 +Abnormality of the upper respiratory tract 0.3259998765165212 1.0037953516873228 0.3154772653737274 1.0 1.0 93 P00813,P21964,P54802,Q96CV9,Q13428,P28070,Q03519,P15586,Q86U42,Q92804,Q15165,P16435,P02545,Q969G3,Q96HY6,P07602,P36543,P50995,P35637,P46100,P09651 21 +Hyporeflexia of upper limbs 0.9504240052185228 1.0037193279346457 0.3155139181829511 1.0 1.0 2 Q9NR77 1 +Deep plantar creases 0.586981575677187 1.000794065159619 0.3169263793910155 1.0 1.0 5 P61978,Q9Y487 2 +Chromosomal breakage induced by ionizing radiation 0.6464693942320905 1.000066611851895 0.3172782727004426 1.0 1.0 4 Q969G3,Q99496 2 +Abnormality of circulating glucocorticoid level 0.4714973533564094 0.9976305071798888 0.318458562194212 1.0 1.0 13 Q13423,P17252 2 +Abnormal glomerular mesangium morphology 0.4465829663596172 0.9960783507319212 0.3192120778311262 1.0 1.0 16 Q8NFH4,P00813,Q14C86,Q8N1F7,Q12769 5 +External ophthalmoplegia 0.434160857644678 0.9959766847530164 0.3192614736588872 1.0 1.0 21 P00403,Q5U5X0,P03915 3 +Limb pain 0.5063460740208319 0.9959509224363304 0.3192739914325697 1.0 1.0 10 P00846,O75477 2 +Osteolytic defects of the distal phalanges of the hand 0.6452942941864539 0.9954099861304144 0.3195369037023798 1.0 1.0 4 O75431,O75844 2 +Central hypoventilation 0.5584858070891511 0.99309564615321 0.3206633455455616 1.0 1.0 7 Q8N183 1 +Fever 0.3172949472319183 0.9923821976413266 0.3210111198208509 1.0 1.0 84 P28070,P00813,Q9NR77,P00403,P23786,P00846,P03915 7 +Round face 0.436682499010184 0.9923529054454956 0.3210254037218003 1.0 1.0 17 P02545,Q03164,Q32P28 3 +Abnormal sharpey fiber morphology 0.5839903915450664 0.9903001646391056 0.3220274261378306 1.0 1.0 6 P02545,P53680 2 +Abnormal nephron morphology 0.4171913591673851 0.989395180324914 0.3224698317122223 1.0 1.0 58 Q8NFH4,O75431,Q9Y276,P00813,P23786,P00403,P00846,P02545,Q14108,Q14C86,Q8N1F7,P03915,Q03252,Q12769 14 +Papillary thyroid carcinoma 0.5181181086072835 0.98845566694931 0.3229295362415152 1.0 1.0 9 Q92785,Q969G3,Q8TAQ2 3 +Ventricular arrhythmia 0.4487126194145544 0.987740901002036 0.3232795577761393 1.0 1.0 36 P23786,P00403,P00846,P42892,P03915,O43772 6 +Elevated hemoglobin a1c 0.583629403388237 0.9864609288716784 0.3239069789984494 1.0 1.0 5 O75431 1 +Increased circulating antibody level 0.4356224515301209 0.985548553172258 0.3243546944277333 1.0 1.0 17 P00813 1 +Adducted thumb 0.4343018752405848 0.983491885286904 0.3253654071551646 1.0 1.0 22 P42892 1 +Rib segmentation abnormalities 0.7389885807504027 0.9818956931110988 0.3261512377835656 1.0 1.0 3 O96028,Q9H3P2 2 +Hypoplastic pubic rami 0.7389885807504027 0.9818956931110988 0.3261512377835656 1.0 1.0 3 O96028,Q9H3P2 2 +Abnormality of abdominal situs 0.7389885807504027 0.9818956931110988 0.3261512377835656 1.0 1.0 3 O96028,Q9H3P2 2 +Aplasia hypoplasia of the pubic bone 0.7389885807504027 0.9818956931110988 0.3261512377835656 1.0 1.0 3 O96028,Q9H3P2 2 +Abnormal sternal ossification 0.7389885807504026 0.9818956931110974 0.3261512377835662 1.0 1.0 3 O96028,Q9Y619 2 +Abnormal coronary artery morphology 0.5816176964891755 0.9800446676060472 0.3270640703597827 1.0 1.0 6 P02545,P34913 2 +Abnormal form of the vertebral bodies 0.3137155484124457 0.9797718360618894 0.3271987572976371 1.0 1.0 81 P48735,P00813,P54802,P46100,O95831,Q32P28,Q96AY3,Q96HY6,Q10713 9 +Retinal dysplasia 0.5161607658127739 0.9785851755398434 0.3277849870191192 1.0 1.0 9 Q10713 1 +Abnormal tricuspid valve physiology 0.4246998190548326 0.9782317835968992 0.3279597000547563 1.0 1.0 18 Q15233,O75431,Q15904,P36543,P46100 5 +Tented upper lip vermilion 0.4310192518863657 0.9748793006020678 0.3296201349049781 1.0 1.0 21 Q4J6C6,Q9UGU0,P46100,Q00577,Q96F07 5 +Synostosis of metacarpals metatarsals 0.7367307809950998 0.9736135695629132 0.3302484461876043 1.0 1.0 3 Q15233 1 +Urinary bladder sphincter dysfunction 0.5148306359170347 0.971880430995589 0.3311100361897341 1.0 1.0 9 P10809,P22626,Q9NR77 3 +Lymphangioma 0.9403131115459852 0.969797566201638 0.3321474062345304 1.0 1.0 2 P48735 1 +Hemangiomatosis 0.9403131115459852 0.969797566201638 0.3321474062345304 1.0 1.0 2 P48735 1 +Visceral angiomatosis 0.9403131115459852 0.969797566201638 0.3321474062345304 1.0 1.0 2 P48735 1 +Venous thrombosis 0.4665130017368309 0.9692117352288442 0.3324395570961564 1.0 1.0 13 P48735 1 +Extrapyramidal muscular rigidity 0.5792939431273209 0.9679494233998316 0.333069629398012 1.0 1.0 5 Q9H6K4 1 +Myotonia 0.5527773685237399 0.9668712427705416 0.3336084041399316 1.0 1.0 7 P02545,Q00577,P50402 3 +Unconjugated hyperbilirubinemia 0.7343864989125384 0.965023546214284 0.3345330182673494 1.0 1.0 3 Q9NSD9 1 +Broad ribs 0.6371804795628195 0.9633151828431354 0.3353893762179676 1.0 1.0 4 P48651 1 +Abnormal renal cortex morphology 0.4343808185606931 0.959119238651742 0.3374986795497428 1.0 1.0 49 Q8NFH4,O75431,P00813,P00403,P00846,P02545,Q16134,Q14108,Q14C86,Q8N1F7,P03915,Q03252,Q12769 13 +Myoclonus 0.3198933628084192 0.9556385562746232 0.3392548749916853 1.0 1.0 90 P07602,Q96CU9,O14936,P00403,Q96F07,P03915,P00846,Q00577,Q01105,Q8NI60,Q969G3,Q9UBX3,Q10713,Q03252 14 +Inappropriate behavior 0.4483530039411277 0.9538959239256232 0.3401363269390898 1.0 1.0 15 P07602 1 +Insulin resistance 0.4395072747428959 0.952116812462699 0.341037743431803 1.0 1.0 16 P02545,O75431,Q03252,O75844 4 +Decreased light and dark adapted electroretinogram amplitude 0.7298531810766549 0.948440523944094 0.3429052375858323 1.0 1.0 3 Q15067,O43837 2 +Hyperconvex fingernails 0.5742717204000474 0.9465457801070416 0.3438702837372842 1.0 1.0 5 O96028,P48651 2 +Excessive salivation 0.4348459589590558 0.9415429417162932 0.346426694134057 1.0 1.0 26 Q15233,P55795,Q9NR77,P15586,P46100,Q03252 6 +Severe muscular hypotonia 0.4394219341944778 0.94115679405042 0.3466245143682442 1.0 1.0 30 P06753,Q8TD16,O95831,P02545,Q00577,Q01105,Q9NWM8,O75381,P56589 9 +Peripheral axonal neuropathy 0.4243343112893553 0.9395068459179152 0.3474705790392387 1.0 1.0 53 P22626,Q8IV08,P07602,Q9BPX6,P00403,O95831,P00846,Q15067,P03915 9 +Lung adenocarcinoma 0.7272430668841765 0.9389102324918358 0.3477768351397508 1.0 1.0 3 P30154,P04637 2 +Abnormal circulating lipid concentration 0.3538206010416955 0.9382125204015952 0.3481352053130317 1.0 1.0 73 O75431,P34913,Q15904,P22830,O43772,Q03252,P28070,O75844,P37268,O75381,P56589,Q15392,P50402,P23786,P02545,Q8N511,P07602,Q92734,Q16836 19 +Abnormality of circulating leptin level 0.7259482803452177 0.9341875410618852 0.3502071613221789 1.0 1.0 3 O75844 1 +Erythema 0.4179157558285472 0.9333049739408492 0.3506625277588941 1.0 1.0 18 P53701,P00403,P22830,Q06136,P03915,P51648,Q07954 7 +Pneumothorax 0.6293900376711857 0.932605730995178 0.3510235732785003 1.0 1.0 4 Q6NUK1,P36543 2 +Upper limb amyotrophy 0.4362143059907148 0.9317021143052494 0.3514904935088139 1.0 1.0 16 P31483,Q9NR77,Q9BQT8,P07196,Q9Y6X9 5 +Disproportionate short limb short stature 0.4265347500753401 0.9273362131221908 0.3537519978421635 1.0 1.0 17 Q15392,Q7LGA3,Q03164,Q14696,Q32P28,O75718 6 +Decreased adipose tissue 0.4439319455181997 0.9273066084990488 0.3537673641403867 1.0 1.0 15 O75431,O75844,P36543,P02545,Q03252 5 +Abnormality of the pubic bone 0.5694595587423079 0.926082048780155 0.3544033422185126 1.0 1.0 5 O96028,Q8IZA0,Q9H3P2 3 +Abnormality of the alveolar ridges 0.5433101466419822 0.9234819535583668 0.3557561006628245 1.0 1.0 7 Q15392 1 +Neonatal hypoglycemia 0.4923130387057808 0.9230990446427744 0.3559555924595252 1.0 1.0 10 O43772 1 +Abnormality of metacarpal epiphyses 0.6263579319704395 0.92068470693281 0.3572150628466064 1.0 1.0 4 O96028,P16435 2 +Impaired pain sensation 0.4179785013908147 0.9175782454040068 0.3588397114625528 1.0 1.0 19 O95831,Q9NR77 2 +Dyspnea 0.3185015325535736 0.9127788230353628 0.3613588782010084 1.0 1.0 92 P07602,P23786,P50995,O75844,Q92734,P35637,Q96CV9,P46100,Q6UN15,O95831,P00846,P02545,Q16134,Q92804,P09651,Q15165,P03915,Q8TCJ2 18 +Glucose intolerance 0.3243408723031882 0.91083453689869 0.3623825621084595 1.0 1.0 99 O75431,Q86Y39,O75844,P00403,Q06136,O96000,Q8N183,O43676,Q13217,P00846,P02545,Q969M3,P17252,Q9Y6M9,P03915,Q03252,Q96CU9 17 +Pseudoarthrosis 0.5657083602148658 0.9101632328719866 0.3627364310644383 1.0 1.0 5 P98172,O75844 2 +Cutaneous cyst 0.7192257394780469 0.9097226245701068 0.3629688094128847 1.0 1.0 3 Q8TAA9 1 +Gowers sign 0.4399514466815558 0.9034165360390606 0.366304867012547 1.0 1.0 15 P06753,Q8TD16,Q8NAT1,P07196,Q9BUK6,Q9Y5P6 6 +Morphological abnormality of the pyramidal tract 0.4221792944824399 0.901953548215134 0.3670815440156452 1.0 1.0 22 P00846,O95831 2 +Abnormal thalamic mri signal intensity 0.5623846697336862 0.897241742201525 0.3695899357041265 1.0 1.0 6 Q969G3,Q9GZY8,Q99496 3 +Abnormality of circulating enzyme level 0.3173514033312076 0.8970323119820327 0.3697016753781785 1.0 1.0 92 Q5JTV8,P06753,Q5JRX3,P07196,Q08J23,O43772,O95831,Q8NAT1,Q86U42,P22626,P23786,P50402,Q9Y584,P02545,P53985,Q9BUK6,O14979,Q9BTV4,Q9BPX6,Q92734,Q96BR5,Q16836,Q9H173,Q9NWM8,P09651 25 +Hip contracture 0.4740820626346583 0.896884472667439 0.3697805664008391 1.0 1.0 11 Q7LGA3,Q96AY3,P06753 3 +Abnormal tissue metabolite concentration 0.4384950291087746 0.8946884300438591 0.3709536652746799 1.0 1.0 15 Q9Y276,P07602,P40855,O75381,P56589 5 +Diaphyseal thickening 0.7150488246108907 0.8945710897850584 0.3710164119348764 1.0 1.0 3 P48651 1 +Abnormal circulating follicle stimulating hormone concentration 0.5361565652169973 0.8908002391402566 0.3730363468496449 1.0 1.0 7 Q969G3 1 +Acidemia 0.4525058629480549 0.8896648779550135 0.3736458583006223 1.0 1.0 13 P48735 1 +Proximal amyotrophy 0.4375487722667683 0.8890216139693302 0.3739914638632364 1.0 1.0 15 Q9BTV4,P50402,Q92734,P35637,P02545,P07196,O14979 7 +Axonal degeneration regeneration 0.6179672493656128 0.8877975343745899 0.3746496694588095 1.0 1.0 4 P02545 1 +Abnormal circulating igg level 0.4363455617405039 0.8818206591210285 0.3778737978708619 1.0 1.0 15 P00813 1 +Hyperventilation 0.507435628615897 0.8742532252497643 0.3819803660559837 1.0 1.0 8 P00846 1 +Aplasia hypoplasia of the lungs 0.4276159309877096 0.8736353898708723 0.3823168469476774 1.0 1.0 28 O95202,Q7Z4L5,O75844,O96028,P41227,O96000,Q9H3P2,P18583,Q92917,Q99567,Q16134,P02545,Q8TAA9,P98175,Q14739,Q6NUK1 16 +Severe short stature 0.4131045749733104 0.8698713506015096 0.384370713605159 1.0 1.0 20 Q15392,P53701,P10619,Q9H173,P16278,Q96HY6,P48651 7 +Undetectable electroretinogram 0.6133531255598482 0.8697816536654978 0.3844197393804265 1.0 1.0 4 O43924,O14773 2 +Distal upper limb amyotrophy 0.4486431433449764 0.8678317022605975 0.3854864722008664 1.0 1.0 13 Q9NR77 1 +Male pseudohermaphroditism 0.7075213012557939 0.867368282672846 0.3857402544601416 1.0 1.0 3 P46100 1 +Limb muscle weakness 0.3163120428644657 0.8596080494930309 0.3900051363396197 1.0 1.0 79 P50336,Q8TB36,P06753,Q13126,P07196,Q15067,Q9Y5P6,Q9NR77,P00846,Q86U42,Q14739,P35670,P10809,P50402,P02545,Q969G3,Q9Y6X9,P31483,Q9BTV4,Q92734,Q96BR5,Q9Y4W6,Q9BQT8,P36551 24 +Distal lower limb muscle weakness 0.4090102048156949 0.8582935404114034 0.390730395422965 1.0 1.0 19 Q9NR77,P06753,P00846,P02545,P07196,Q9Y5P6 6 +Abnormality of the nasal bone 0.6103995349562823 0.8582771917305269 0.3907394206979797 1.0 1.0 4 Q6NUK1,O14974 2 +Astrocytoma 0.5033056273909445 0.8541930811075377 0.3929980161627555 1.0 1.0 8 O75874,P48735 2 +Large placenta 0.7029191577945102 0.8508067410530739 0.394876716402349 1.0 1.0 3 O75844 1 +Abnormal fallopian tube morphology 0.5514482789011942 0.8499539451433338 0.3953506918547314 1.0 1.0 5 P49959,P04637,P53701 3 +Poor appetite 0.4517160798813818 0.8489704638394049 0.3958977276533331 1.0 1.0 12 Q70HW3 1 +Neoplasm of the thyroid gland 0.4142361392871919 0.8488367597452426 0.3959721323510896 1.0 1.0 22 Q8TAQ2,Q92785,P02545,P21912,P42892,Q969G3,P20585 7 +Abnormality of neutrophil morphology 0.5510240014399126 0.8486797944945221 0.3960594923752396 1.0 1.0 6 Q14739,P41440 2 +Abnormality of somatosensory evoked potentials 0.7017944535073277 0.8467677685508687 0.3971245769223941 1.0 1.0 3 Q9Y6X9,P20700 2 +Tetraplegia 0.4445986069416847 0.8450288932980136 0.3980947072251173 1.0 1.0 13 Q13423,P51572,O95831 3 +Punctate cataract 0.6065034907917737 0.8431369315243407 0.399151865979737 1.0 1.0 4 P08670 1 +Paresthesia 0.4146241620081656 0.83832324130055 0.4018491863195861 1.0 1.0 23 P54802,Q9NR77 2 +Ovarian cyst 0.4432061453086108 0.8371931263783501 0.4024840205128273 1.0 1.0 13 P78549,P16435,P02545,P21912,P20585,Q03252 6 +Sclerocornea 0.4996908666307466 0.8366696821096881 0.4027782653269036 1.0 1.0 8 O95202,P53701,O96028,Q9H3P2,O75569,P49454 6 +Iron deficiency anemia 0.5228743037070988 0.8304188892697744 0.406301989459211 1.0 1.0 7 P46100 1 +Abnormal endocrine physiology 0.546088631213801 0.827683956296002 0.4078495074447437 1.0 1.0 6 Q13423,P16435 2 +Tremor by anatomical site 0.4161097599472947 0.8244594423405692 0.409678551600152 1.0 1.0 25 Q9NR77,Q92734,P35637,Q9Y4W6,Q96KR1,P07196,P20700 7 +Exercise intolerance 0.4225963618026586 0.823594724625407 0.4101698744431075 1.0 1.0 30 P23786,P00403,Q8NI60,Q9Y2R0,P03915 5 +Glioma 0.4469117764206229 0.822657525801972 0.4107027755027668 1.0 1.0 12 O75874,P48735 2 +Lower limb amyotrophy 0.4031811201413475 0.8199644685004841 0.4122363630051731 1.0 1.0 19 Q9NR77,P06753,Q92734,Q8TD16,P02545,P07196,Q9Y6X9 7 +Elevated pulmonary artery pressure 0.4077804687528335 0.8199029748369624 0.4122714207702107 1.0 1.0 21 O75844,P00403,O96000,P02545,Q8IZA0,P03915 6 +Abnormal circulating bilirubin concentration 0.4170000285189285 0.819756824854949 0.4123547485082333 1.0 1.0 26 P55263,O14936,P23786,P41440,P40855,P36551,Q14739,Q9NSD9,P28288 9 +Calvarial skull defect 0.5437342208623421 0.8176918578616599 0.4135331608478574 1.0 1.0 6 O96028,Q14739,Q9H3P2 3 +Abnormal epiphyseal ossification 0.4255705906415769 0.8175971692250269 0.4135872444680888 1.0 1.0 15 Q96HY6,O75381 2 +Abnormal talus morphology 0.409117346985653 0.8166056063796643 0.4141538501553357 1.0 1.0 17 O75844,Q99567,P16435,P02545,P98175,Q9UPT5 6 +Increased circulating acth level 0.5434133755627433 0.8162762975963079 0.4143421275904355 1.0 1.0 5 P46100,P16435 2 +Abnormal brainstem mri signal intensity 0.4090926765857943 0.8146105626851085 0.4152952623581898 1.0 1.0 22 Q86Y39,O96000,O43676,O95831,Q9Y6M9,Q96CU9 6 +Chordee 0.5424743555681446 0.8123516575524926 0.4165898769760594 1.0 1.0 6 P48651,P16435,O14974 3 +Heterotaxy 0.5984932209388796 0.8121430867978849 0.4167095321534138 1.0 1.0 4 O96028,Q9H3P2 2 +Ventricular tachycardia 0.4312425726005832 0.8079738143461452 0.4191056565569664 1.0 1.0 14 O43772 1 +Macrovesicular hepatic steatosis 0.5176207137024504 0.8066644175583783 0.4198598496205883 1.0 1.0 7 P23786 1 +Stiff skin 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Severe failure to thrive 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Abnormal sweat gland morphology 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Patchy alopecia 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Epidermal hyperkeratosis 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Aplasia hypoplasia of the colon 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Prominent umbilicus 0.8904109589041083 0.8057610480541225 0.420380641665588 1.0 1.0 2 O75844 1 +Xanthomatosis 0.8904109589041074 0.8057610480541202 0.4203806416655893 1.0 1.0 2 P34913 1 +Transposition of the great arteries 0.5967875861781486 0.8055683876790621 0.4204917593380521 1.0 1.0 4 O75844 1 +Fatty replacement of skeletal muscle 0.5173083312107449 0.805254541554122 0.4206728083266857 1.0 1.0 7 P22626,P09651 2 +Choanal stenosis 0.6898677300082539 0.8041557202740635 0.4213070479110883 1.0 1.0 3 P48651 1 +Gaze evoked nystagmus 0.48050353579417 0.8000596831650341 0.4236762185748195 1.0 1.0 9 Q10713 1 +Infantile spasms 0.4166575341036894 0.7983550716912596 0.4246644677590223 1.0 1.0 28 P00846,Q9UBX3 2 +Hypoplastic vertebral bodies 0.538326400930547 0.7948039044883677 0.4267275794112053 1.0 1.0 6 Q14739,P16278 2 +Abnormal paranasal sinus morphology 0.409889463485768 0.7942727107655496 0.4270366871430822 1.0 1.0 24 P28070,P00813,P46100 3 +Abnormal blood transition element cation concentration 0.4540596017213301 0.7907304753180439 0.4291012883251803 1.0 1.0 11 Q15904,Q9Y276,P35670,P28288 4 +Agitation 0.4200816139284684 0.7888664619891874 0.4301900594472143 1.0 1.0 33 P50995,Q96CV9,P35637,Q92804,P42892,Q15165,P09651 7 +Abnormal magnesium concentration 0.5363768643616725 0.7865753251271502 0.4315305084063234 1.0 1.0 6 P61457,P05023,P53680 3 +Thick corpus callosum 0.6847627822386143 0.7860471442448846 0.4318398681346467 1.0 1.0 3 Q15233 1 +Axonal loss 0.535402539022507 0.7824675935610335 0.43393982313634 1.0 1.0 6 P41440 1 +Abnormal thalamic size 0.6835895442014046 0.7818971562115657 0.4342750164277413 1.0 1.0 3 Q9UPT5 1 +Abnormal gastrointestinal motility 0.4061535297124399 0.781852749253712 0.4343011165654902 1.0 1.0 23 Q9NSE4,P00403,P35637,P61978,P03915 5 +Abnormal motor nerve conduction velocity 0.3995277202925545 0.7804052078004783 0.4351524034783276 1.0 1.0 20 Q9NR77 1 +Abnormal left ventricle morphology 0.4091033959855556 0.7773356093288842 0.4369607912207582 1.0 1.0 25 P00403,O75431,P03915 3 +Heart block 0.4072043536000602 0.7763455577106981 0.4375449805162423 1.0 1.0 24 Q9BTV4,P23786,P50402,P36543,P02545,O43772 6 +Long thorax 0.6819041164166675 0.7759433765176229 0.437782419633892 1.0 1.0 3 P17252 1 +Retinal vascular tortuosity 0.4184455192374845 0.775433285344445 0.4380836730818802 1.0 1.0 15 P00846,P49454,P03915 3 +Abnormality of the supraorbital ridges 0.402789274492785 0.7728810560130933 0.4395927770875414 1.0 1.0 22 P38159,P98175,P40855,O75381,P56589,Q08J23 6 +Short lingual frenulum 0.6808692763672177 0.7722924966537299 0.4399412084519971 1.0 1.0 3 O75844 1 +Overtubulated long bones 0.6808692763672177 0.7722924966537299 0.4399412084519971 1.0 1.0 3 O75844 1 +Retinal pigment epithelial atrophy 0.5879174037191671 0.7715290707018652 0.4403933980893009 1.0 1.0 4 P51648 1 +Insulin resistant diabetes mellitus 0.4860936203596042 0.7710895142030437 0.4406538754351081 1.0 1.0 8 O75431,O75844 2 +Hemiplegia hemiparesis 0.4157908363856051 0.7697206485470084 0.4414656188579204 1.0 1.0 31 P00403,P03915 2 +Abnormal biliary tract morphology 0.3999023589016742 0.767983460886715 0.4424970108859769 1.0 1.0 21 Q9Y276,P07602,Q5XKP0,P02545,Q14108,Q14739,Q9NSD9,Q10713 8 +Aplasia hypoplasia of the clavicles 0.4367987871085846 0.7675997103853273 0.4427250345221023 1.0 1.0 12 O75431,O75844,P41227,P98172,P02545,P48651 6 +Abnormal nasolacrimal system morphology 0.4617160770235696 0.7659583422709326 0.4437010895370907 1.0 1.0 10 Q13428,Q9UQE7,P48651,P53701 4 +Abnormal jejunum morphology 0.8770384866275276 0.7629905800052846 0.4454690137846602 1.0 1.0 2 O14974 1 +Extra axial cerebrospinal fluid accumulation 0.8767123287671208 0.7619548181943406 0.4460869707405543 1.0 1.0 2 Q03252 1 +Vertebral hypoplasia 0.4606158618523087 0.7603699138216082 0.4470335018911373 1.0 1.0 10 Q14739,Q96HY6,P16278 3 +Decreased activity of mitochondrial complex i 0.4161574352948073 0.7570073814297883 0.4490454402067814 1.0 1.0 34 Q86Y39,Q70HW3,O96000,O43676,Q9Y584,Q9Y6M9,Q9UBX3,Q96CU9 8 +Epiretinal membrane 0.6763756811634399 0.7564817320819324 0.4493604210531265 1.0 1.0 3 P04439 1 +Bile duct proliferation 0.6759185575863664 0.7548772872283745 0.4503226148965313 1.0 1.0 3 Q9NSD9 1 +Myopathy 0.3065612654808464 0.7501022994316395 0.4531930947410654 1.0 1.0 92 P22626,Q86Y39,P23786,P00403,P50402,O43676,Q13126,P00846,P02545,P17252,Q9NWM8,P09651,P49454,P03915,Q9BUK6,O14979,Q03252 17 +Biliary tract abnormality 0.4009488426196901 0.7473879018368678 0.4548294460440303 1.0 1.0 23 Q9Y276,P07602,O96028,Q5XKP0,P02545,Q14108,Q14739,Q9NSD9,Q10713 9 +Abnormal choroid morphology 0.4077157620758597 0.7469070568072163 0.455119665969625 1.0 1.0 27 P04439,Q9Y619,O14936,P53701,P41227,O60826,Q8NAT1,P40855,O75381,P56589,Q10713 11 +Agenesis of incisor 0.6734094616639383 0.7460840015750679 0.4556166729924771 1.0 1.0 3 P41227,Q12959 2 +Reduced subcutaneous adipose tissue 0.4695523125365688 0.7459724960531771 0.4556840297805955 1.0 1.0 9 P02545,O75844,P36543 3 +Areflexia of lower limbs 0.3941380241321799 0.7452086477154733 0.4561455958678702 1.0 1.0 20 Q9H6K4,Q15067,Q13217,Q9NR77 4 +Supernumerary nipple 0.4571201147805804 0.7426496965247155 0.457693792363667 1.0 1.0 10 Q7LGA3,P61978 2 +Protruding tongue 0.4568204752830306 0.7411334332228251 0.4586125398277838 1.0 1.0 10 P20700,P46100,Q10713 3 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3955943229617968 0.7397708312497213 0.4594390608058289 1.0 1.0 21 P00846,O96000,P03915,P22695 4 +Retinal detachment 0.4123265667351483 0.7394557641468166 0.4596302914712291 1.0 1.0 15 P04439,Q14118,Q99496,P35222,Q14331,O75533,Q8NAT1,Q9Y5P6 8 +Diffuse cerebral atrophy 0.412266592100427 0.7391043004500909 0.4598436657043048 1.0 1.0 15 Q10713 1 +Gastrostomy tube feeding in infancy 0.40891895582031 0.7370539045938637 0.4610895693194199 1.0 1.0 29 P37268,P35637,O15121,Q01105,P17480 5 +Lymphopenia 0.4072339087949324 0.7342334084832177 0.4628064953421607 1.0 1.0 28 P00813 1 +Increased bone mineral density 0.4001395662869526 0.7294229129854961 0.4657430061133856 1.0 1.0 24 Q15392,Q15043,P54802,Q13126,P02545,P48651 6 +Progressive neurologic deterioration 0.3913742822007315 0.7272440743717603 0.4670764509605409 1.0 1.0 20 P07602,Q10713 2 +Abdominal pain 0.3112377261541719 0.7252835996377998 0.4682780649524143 1.0 1.0 78 Q13423,P23786,Q70HW3,P35637,P42892 5 +Lacrimal duct stenosis 0.8649706457925617 0.7249185741523658 0.4685019852167875 1.0 1.0 2 P48651 1 +Steppage gait 0.3909437261282895 0.7244508631846455 0.4687889831995637 1.0 1.0 20 P31483,Q9NR77,Q96BR5,P02545,P07196 5 +Contractures of the joints of the lower limbs 0.396941885475546 0.7227346986002705 0.4698428933926812 1.0 1.0 54 Q5JTV8,Q9BTV4,P06753,P37268,P50402,P23786,Q7LGA3,P35637,Q8TD16,P02545,Q8IZA0,O75477,Q96AY3,Q86XL3,Q08J23,P48651 16 +Abnormality of the intervertebral disk 0.5199962483172628 0.7194166066209271 0.4718842677619661 1.0 1.0 5 P02545,Q8WUM0,P57740 3 +Anhidrosis 0.5199512696404993 0.7177841971152826 0.4728903587093231 1.0 1.0 6 P20700,Q9Y276,Q9H4A3 3 +Hepatoblastoma 0.4519429500044871 0.7165134140676197 0.47367438768027 1.0 1.0 10 Q92785,Q969G3,Q8TAQ2 3 +Epiphora 0.5731390838074544 0.7154491188463566 0.4743315704265254 1.0 1.0 4 Q15043 1 +Abnormal clavicle morphology 0.3894591233331801 0.7148312211443442 0.4747133406129094 1.0 1.0 20 O75431,Q9Y5S9,O75844,P41227,P98172,P02545,Q96AY3,Q14739,P48651 9 +Delayed menarche 0.5191238162682018 0.7143467150082483 0.4750128123487558 1.0 1.0 6 O75844 1 +Asymmetric septal hypertrophy 0.8610567514677024 0.712686211158369 0.4760399508683586 1.0 1.0 2 P54802 1 +Abnormal circulating carbohydrate concentration 0.4108284940667674 0.7101087671533498 0.4776366900352971 1.0 1.0 39 Q86Y39,Q70HW3,Q5JRX3,O96000,O43676,Q9BWD1,O95831,P22695,Q9Y6M9,Q96CU9 10 +Cervical ribs 0.6629581941781182 0.7097102862952884 0.4778838120838056 1.0 1.0 3 Q9Y5S9 1 +Pain 0.3637240426528865 0.7066767122787955 0.4797674046783051 1.0 1.0 171 O14936,Q70HW3,P21964,Q96CV9,Q15043,O75477,Q14108,P42892,Q03252,Q9H6K4,P28070,Q9NR77,O75844,P00846,Q92804,O75874,Q15165,Q13423,P48735,P22626,P23786,P50402,P02545,Q969G3,Q96HY6,Q9BUK6,Q8NFH4,P07602,P50995,Q6UN15,P35637,P46100,P20700,P09651 34 +Atrial arrhythmia 0.4947243312922716 0.7042355208001743 0.4812861136108946 1.0 1.0 7 P02545,P50402 2 +Pituitary hypothyroidism 0.5166419314585787 0.7040538460909942 0.4813992412300809 1.0 1.0 6 O00170,Q969G3,Q99496 3 +Dilated cardiomyopathy 0.4090615295916291 0.7033391442413887 0.4818444216865525 1.0 1.0 35 Q9BTV4,P23786,P00403,P06753,Q16836,P00846,P02545,P16278,P03915 9 +Meningioma 0.4941999188690939 0.7019140414503999 0.482732771646283 1.0 1.0 7 P02545,Q969G3,P21912,P78549 4 +Elevated circulating long chain fatty acid concentration 0.8574690150032516 0.7015252562983593 0.4829752785779133 1.0 1.0 2 P23786 1 +Multicystic kidney dysplasia 0.3983741370148359 0.7005128468229538 0.4836070850664813 1.0 1.0 16 Q10713,O75381 2 +Pain in head and neck region 0.4920663527650644 0.6924820246082382 0.4886346705228943 1.0 1.0 7 Q969G3 1 +Retinal thinning 0.8542074363992171 0.6914232643653512 0.4892995882486504 1.0 1.0 2 P51648 1 +Aplasia hypoplasia involving the vertebral column 0.4036818257574692 0.6890545852295932 0.490788917886749 1.0 1.0 15 O95831 1 +Widow s peak 0.5660367377448488 0.6888146517878524 0.4909399140987789 1.0 1.0 4 P98172 1 +Optic nerve hypoplasia 0.3803593438947967 0.6885643345906318 0.4910974716725906 1.0 1.0 18 O14936,P37268,P61978,P49454,P07196,Q8N3U4 6 +Pili torti 0.8532289628180008 0.6884010540432577 0.4912002602577392 1.0 1.0 2 P02545 1 +Muscular dystrophy 0.4000834460321245 0.6860528099733006 0.4926798072323075 1.0 1.0 28 Q5JTV8,P22626,Q9BTV4,P50402,Q9H173,P02545,Q8NAT1,P09651,O14979 9 +Hypoplastic fifth toenail 0.4680967772576899 0.6853272332665495 0.4931374505182933 1.0 1.0 8 Q92785,Q969G3,Q8TAQ2 3 +Enchondroma 0.4568396126039793 0.6838349401160597 0.494079400531799 1.0 1.0 9 O75874,P48735 2 +Abnormality of tibia morphology 0.4211981458378308 0.6837516002412161 0.4941320338399038 1.0 1.0 12 O95831 1 +Progressive visual loss 0.390489741542858 0.6787767838817749 0.497279306017564 1.0 1.0 23 P00846,P03915 2 +Mildly elevated creatine kinase 0.3837533391372946 0.6780375524430855 0.4977478835328957 1.0 1.0 20 Q9BPX6,Q92734,Q16836,P02545,P09651,Q9BUK6 6 +Elbow ankylosis 0.849641226353552 0.6773533508108082 0.4981817885833646 1.0 1.0 2 P48651 1 +Humeroradial synostosis 0.849641226353552 0.6773533508108082 0.4981817885833646 1.0 1.0 2 P48651 1 +Cardiovascular calcification 0.4663980882683178 0.6773067694218619 0.4982113367507543 1.0 1.0 8 O75431,O75844 2 +Urinary glycosaminoglycan excretion 0.4885730485536113 0.6770850003944653 0.4983520252098863 1.0 1.0 7 P54802,P15586 2 +Tetraplegia tetraparesis 0.401921532547652 0.6761654757681155 0.4989355894836964 1.0 1.0 47 Q5U5X0,Q13423,P07602,Q92734,P35637,O95831,P00846,P51572,Q9UBX3 9 +Persistent head lag 0.488195044153494 0.6754224486525202 0.4994074070665948 1.0 1.0 7 Q15233,Q9NSD9 2 +Abnormal number of incisors 0.5089232075247538 0.6722201498590946 0.5014435550251723 1.0 1.0 6 P41227,Q8N3U4 2 +Accessory spleen 0.508047132242046 0.6686248360122766 0.5037348255535747 1.0 1.0 6 Q15904,P49454 2 +Abnormal granulocytopoietic cell morphology 0.6508972267536646 0.6682849165610023 0.5039517396411601 1.0 1.0 3 Q07020,Q14980 2 +Profound global developmental delay 0.4063433272049693 0.6663996718881677 0.5051556721731645 1.0 1.0 14 P37268,P56589,P46100,O75381 4 +Spastic ataxia 0.4640522875817012 0.6662547796594176 0.5052482641854059 1.0 1.0 8 Q9NVV4,Q96GW9,Q86SX6,Q9Y4W6,Q15813,Q6PI48,Q9H3L0 7 +Fasciculations 0.4037416098831284 0.6659425601774775 0.5054478154830471 1.0 1.0 35 P22626,P07602,Q92734,Q96CV9,P35637,O95831,Q9BQT8,P09651 8 +Extramedullary hematopoiesis 0.5585792902679068 0.6610956594370527 0.508550968736365 1.0 1.0 4 P98175 1 +Retinal dystrophy 0.3931504920360479 0.6601920951668945 0.5091305643856627 1.0 1.0 52 P10809,Q13868,P00846,Q8NAT1,P40855,O75381,Q15067,P56589,P03915,Q10713,Q6P4Q7 11 +Enlarged ovaries 0.6484287951255867 0.6598852306048917 0.5093274828213619 1.0 1.0 3 P16435 1 +Inferior lens subluxation 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Uveal melanoma 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Choroidal melanoma 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Lens subluxation 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Abnormal ciliary body morphology 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Metamorphopsia 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Mydriasis 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Photopsia 0.6482871125611742 0.659403953250121 0.5096364042206001 1.0 1.0 3 O75533,Q99496 2 +Progressive muscle weakness 0.4109978531074543 0.6587763146317713 0.5100394190215072 1.0 1.0 13 O75381,P56589,P40855,P06753 4 +Neoplasm of the endocrine system 0.4027316346808815 0.655701957270139 0.5120159092780072 1.0 1.0 36 P48735,P46100,P02545,P42892,Q969G3,O75874 6 +Zonular cataract 0.439476040479934 0.654171982292778 0.5130010101401568 1.0 1.0 10 P08670 1 +Distal muscle weakness 0.3693437165409884 0.6537535510620701 0.5132705961663933 1.0 1.0 62 P06753,P07196,Q9Y5P6,Q9NR77,O95831,Q8TD16,P00846,Q86U42,P22626,P02545,Q9Y6X9,Q9BX10,P31483,P41440,P35637,Q96BR5,Q9Y4W6,Q9BQT8,P36551,P09651 20 +Arnold chiari type i malformation 0.5563655207872353 0.6529189289172997 0.5138085450859955 1.0 1.0 4 Q15233 1 +Abnormality of the 5th toe 0.5039575124163717 0.6518922234699644 0.5144707019378236 1.0 1.0 6 O43924,Q14739,Q10713 3 +Postaxial foot polydactyly 0.5039575124163717 0.6518922234699644 0.5144707019378236 1.0 1.0 6 O43924,Q14739,Q10713 3 +Middle age onset 0.4501243220372406 0.6513481684930198 0.514821761008792 1.0 1.0 9 P07602,Q15126 2 +Waddling gait 0.3897397670395597 0.649044702645432 0.516309482421581 1.0 1.0 25 Q4J6C6,P22626,Q9BTV4,P06753,P50402,Q8TD16,P02545,Q5T8D3,P07196,P09651,Q9Y5P6 11 +Underdeveloped nasal alae 0.376562763097541 0.6478881990575645 0.5170572639269166 1.0 1.0 19 O75431,P55795,P61978,Q00577,Q08J23 5 +Pancreatitis 0.3832803754461558 0.645663913809971 0.5184970355714555 1.0 1.0 22 P00403 1 +Palpebral edema 0.501666046716408 0.6452887887992056 0.5187400566339089 1.0 1.0 5 O00170,Q14331 2 +Abnormality of the larynx 0.4011446201454607 0.6436224965822647 0.5198202585367138 1.0 1.0 42 P07602,P21964,P50995,Q96HY6,Q96CV9,P35637,P16435,P02545,Q92804,Q15165,P09651 11 +Abnormal macroscopic urine appearance 0.3811120355618866 0.6423931892183675 0.5206179207676798 1.0 1.0 17 Q8NFH4,O43707,Q9BW27,P23786,P36551,Q8WUM0,Q14C86,Q8N1F7,Q12769 9 +Ectrodactyly 0.4016588227983467 0.6402564833348765 0.522005866965364 1.0 1.0 14 Q8TB36,Q9NR77,O96028,Q9H3P2,P07196,Q9Y6X9 6 +Abnormality of the shoulder girdle musculature 0.3945233212894373 0.6399058411035675 0.5222338162382458 1.0 1.0 29 Q9BTV4,P07602,Q9Y487,P06753,P50402,Q8TD16,P02545,P07196,O14979,Q9Y5P6 10 +Slowly progressive 0.3851238813785694 0.6393575733917259 0.5225903425248721 1.0 1.0 55 Q5JTV8,Q9BTV4,Q8IV08,Q9NR77,P50402,P41440,O14773,Q96BR5,Q92734,Q9Y4W6,O95831,P02545,Q9P0J0,P07196,Q9Y6X9,O14979 16 +Limited elbow extension 0.4582751500559007 0.6391607722200252 0.5227183484355158 1.0 1.0 8 Q9H6K4,Q8WVM7 2 +Abnormal response to endocrine stimulation test 0.5518985318108194 0.6364955422795926 0.5244534855315819 1.0 1.0 4 Q13423 1 +Glomerular sclerosis 0.3952230293413123 0.6363375207715327 0.5245564544105528 1.0 1.0 30 Q8NFH4,O75431,P00403,Q14108,Q14C86,Q8N1F7,P03915,Q12769 8 +Abnormal speech prosody 0.4575694846783993 0.6358639905123568 0.5248650749121855 1.0 1.0 8 P00846 1 +Abnormal circulating igm level 0.3874714945312539 0.6356624901993865 0.5249964297217733 1.0 1.0 16 P00813 1 +Abnormal morphology of the radius 0.4113111623968689 0.6314623029593136 0.52773829009252 1.0 1.0 12 Q32P28 1 +Aspiration pneumonia 0.3886856836878191 0.6308100375130004 0.5281647395306959 1.0 1.0 26 P06753,Q92734,Q969G3,O95721,Q8TAQ2,Q92785,Q00577,O60220,P16278,P78318,Q8N3U4,P20700,Q6NUK1,O14497 14 +Abnormality of upper limb joint 0.3088793016101925 0.6243773591014261 0.5323797904757233 1.0 1.0 106 P06753,P98172,P16278,P07196,P42892,Q9H6K4,Q15233,Q9NR77,O75844,P37268,Q03164,O95831,Q8IZA0,Q15392,P23786,P50402,Q7LGA3,P16435,P02545,Q96AY3,P48651,Q9BTV4,O96028,Q9H173,Q8WVM7 25 +Ketoacidosis 0.4440038367678419 0.6219715799478247 0.5339605558021834 1.0 1.0 9 P53985 1 +Abnormal circulating sulfur amino acid concentration 0.4531028552108019 0.6150642413157065 0.5385122960564805 1.0 1.0 8 P41440 1 +Neoplasm of the adrenal gland 0.407313714781795 0.6105417235892553 0.5415030132581311 1.0 1.0 12 P48735 1 +Increased intracranial pressure 0.3678417339565155 0.609410492283204 0.5422523849847227 1.0 1.0 18 P07602 1 +Brain imaging abnormality 0.3946979869489985 0.607447886423458 0.5435537173259914 1.0 1.0 34 P07602,P00403,Q00577,Q969G3,P03915 5 +Pterygium 0.4065144862453704 0.6063754525496606 0.5442654651881937 1.0 1.0 12 Q96AY3 1 +Polymicrogyria 0.3017689996791951 0.6062046905332378 0.5443788384629871 1.0 1.0 78 Q01105,Q08J23,Q9Y5P6,P37268,Q8TD16,Q96EK5,Q8NAT1,P40855,O75381,P56589,Q10713,O00459,Q15392,P23786,P34897,Q96N66,P36543,O14974,O95721,Q16625 20 +Sea blue histiocytosis 0.8258317025440234 0.6054711513985972 0.5448659873452255 1.0 1.0 2 O15118 1 +Prominent sternum 0.8258317025440178 0.6054711513985802 0.5448659873452368 1.0 1.0 2 O95831 1 +Limited hip movement 0.3947097995858215 0.6018314139791411 0.5472863621410831 1.0 1.0 14 O75844,P06753,Q7LGA3,P02545,Q96AY3 5 +Intestinal hypoplasia 0.5422672467916284 0.6014496598357973 0.547540531235926 1.0 1.0 4 P02545,O75844 2 +Congenital muscular dystrophy 0.8235485975211945 0.5987182317099498 0.5493607972880381 1.0 1.0 2 P02545 1 +Short nail 0.5410652046228227 0.5971125120040739 0.5504322648407218 1.0 1.0 4 P02545,O75844 2 +Impaired proprioception 0.394482228502463 0.5952695146837245 0.5516633301734233 1.0 1.0 37 P10809,Q8IV08,Q9NR77,P41440,P54802,P00846 6 +Increased csf lactate 0.3833357195710673 0.59334698626856 0.5529489598282122 1.0 1.0 53 Q86Y39,Q8N183,P00403,O96000,O43676,O95831,P00846,Q8NI60,Q9Y6M9,P03915,Q96CU9 11 +Enlarged thorax 0.3729095361626144 0.5926813049737827 0.5533944551592431 1.0 1.0 17 O75844,P41227,P02545,Q32P28,P17252 5 +Periorbital edema 0.3769800454763586 0.5917327073237505 0.554029590931163 1.0 1.0 23 Q8NFH4,P28070,O43707,Q9BW27,O00170,Q14331,Q8WUM0,Q14C86,Q8N1F7,P35250,Q12769 11 +Aplasia cutis congenita of scalp 0.4875547820190211 0.5894960002897859 0.5555285944465611 1.0 1.0 5 O96028,Q9H3P2 2 +Short columella 0.8199608610567467 0.5881591798556395 0.5564254536593485 1.0 1.0 2 P49454 1 +Aplasia hypoplasia of the tongue 0.5382926239347607 0.5871411594873513 0.55710890636758 1.0 1.0 4 Q03252 1 +Microglossia 0.5382926239347607 0.5871411594873513 0.55710890636758 1.0 1.0 4 Q03252 1 +Aplasia hypoplasia of the optic nerve 0.3760426468517582 0.5857705579647212 0.5580297114242145 1.0 1.0 23 O14936,P37268,P61978,P49454,P07196,Q8N3U4,O95721 7 +Abnormality of pulmonary circulation 0.3773601327921531 0.5812283533427016 0.5610865607907662 1.0 1.0 24 O75844,P00403,O96000,P02545,Q8IZA0,P03915 6 +Scanning speech 0.817351598173514 0.5805210288086979 0.56156330996884 1.0 1.0 2 O14773 1 +Cerebral calcification 0.38977325127636 0.5792227229402761 0.5624389003848478 1.0 1.0 33 P00403,P23786 2 +Dry skin 0.3896403372589291 0.5783257019714586 0.5630442450976212 1.0 1.0 33 P00813,Q2TAA5,P37268,Q06136,P11802,Q9NYB0,Q08J23 7 +Caesarian section 0.535783099810547 0.5781558189475944 0.5631589241712742 1.0 1.0 4 Q96EY7 1 +Hypokinesia 0.4125284526499238 0.5770158038229017 0.5639287795944332 1.0 1.0 11 Q9Y3D3,O95831,Q2TAA5,P06753 4 +Aplasia of the uterus 0.485135222233921 0.5760711247602414 0.5645671078722214 1.0 1.0 6 O96028,Q9Y5S9 2 +Abnormality of temperature regulation 0.3027126451002402 0.5755920410521327 0.5648909619292806 1.0 1.0 103 P00813,O14936,P00403,Q14C86,O43772,P28070,Q9NR77,P35610,P61978,P00846,P51572,Q8N3U4,P23786,Q8N1F7,P03915,Q8NFH4,P07602,Q2TAA5,Q6UN15,P20700 20 +Median cleft palate 0.8150684931506815 0.5738665784318964 0.5660580909148933 1.0 1.0 2 Q8N3U4 1 +Pancreatic islet cell hyperplasia 0.8150684931506753 0.5738665784318779 0.5660580909149058 1.0 1.0 2 P53985 1 +Rod cone dystrophy 0.3913124116315913 0.5710994700479738 0.5679322178129222 1.0 1.0 38 P10809,P00846,O75381,Q15067,P03915 5 +Hyporeflexia of lower limbs 0.4331354844770304 0.570424204928888 0.5683900164725935 1.0 1.0 9 Q9NR77 1 +Abnormality of macular pigmentation 0.6215334420880873 0.5703196140990345 0.5684609400177845 1.0 1.0 3 P55265,P35221 2 +Abnormality of the achilles tendon 0.3936669265264638 0.5658909433393182 0.5714679185804263 1.0 1.0 13 P50402,Q92734,Q8TD16,P02545,Q08J23 5 +Dysmenorrhea 0.8095238095238027 0.5578205947058178 0.5769668980289491 1.0 1.0 2 P02545 1 +Muscle spasm 0.3713515492068233 0.55750198168577 0.5771845055006701 1.0 1.0 57 Q9H6K4,Q9NR77,P23786,P50995,Q92734,Q96CV9,P35637,P53985,P00846,Q92804,Q15165 11 +Abnormality of the tarsal bones 0.3669409226041733 0.5565060023826081 0.5778649922654786 1.0 1.0 21 O75844,Q99567,P16435,P02545,P98175,Q14739,Q9UPT5 7 +Abnormal atrioventricular conduction 0.3798598800302185 0.5534895713222767 0.5799282197106961 1.0 1.0 15 P02545,O43772,P50402 3 +Hypotension 0.3783300872209921 0.55289499083438 0.5803353176858734 1.0 1.0 27 Q13423,P07602,O43772 3 +Prostate neoplasm 0.4756066868360336 0.543279428073739 0.5869374261638027 1.0 1.0 5 P49959,P04637 2 +Somatic sensory dysfunction 0.2968539974435026 0.542178146240066 0.5876957886059189 1.0 1.0 99 Q9H6K4,P10809,Q8IV08,P07602,Q9NR77,P41440,Q9NSE4,Q92734,P54802,P61978,Q96BR5,O95831,P00846,P02545,Q13217,P17480,Q9BUK6 17 +Short ribs 0.4370155536527159 0.5412287394106134 0.5883499307740958 1.0 1.0 8 Q14739,Q9Y619,Q96HY6 3 +Recurrent fractures 0.3792733234300486 0.539501211299428 0.5895410613921903 1.0 1.0 29 Q13126,P48735,Q32P28,Q96AY3 4 +Abnormal tongue physiology 0.3638995756710869 0.5389791717279047 0.5899012263129448 1.0 1.0 17 Q9BQT8,O95831 2 +Unusual infection by anatomical site 0.3769566722696998 0.5373761144813263 0.5910078388366109 1.0 1.0 15 Q14739,Q8TAA9,O15460,P46100 4 +Soft skin 0.4359574057831185 0.5364376223091181 0.5916561356545249 1.0 1.0 8 Q13126 1 +Atrophy degeneration involving the corticospinal tracts 0.3877098935489952 0.5346440491052735 0.5928960178751721 1.0 1.0 13 P00846 1 +Widened subarachnoid space 0.3766305571094644 0.5318548599502873 0.5948265233122805 1.0 1.0 28 P00403,P03915,Q2TAA5,O95831 4 +Cystic hygroma 0.4541749441191051 0.5291766170889202 0.5966829358626122 1.0 1.0 7 Q14739,P61978 2 +Oromotor apraxia 0.5215212954029552 0.5278579095671554 0.5975979602630277 1.0 1.0 4 Q8N3U4 1 +Abnormality of the thyroid gland 0.2946691202032815 0.5245131651433309 0.5999216654745503 1.0 1.0 98 Q13423,P48735,P00813,P00403,P21964,P61978,Q13868,P02545,P42892,Q969G3,P20585,P03915,Q9BUK6,O75874,Q13428 15 +Abnormal subcutaneous fat tissue distribution 0.6066986161433254 0.5226494003900755 0.601218256283856 1.0 1.0 3 P36543 1 +Prominent veins on trunk 0.6066986161433254 0.5226494003900755 0.601218256283856 1.0 1.0 3 P36543 1 +Abnormal circulating apolipoprotein concentration 0.6066986161433254 0.5226494003900755 0.601218256283856 1.0 1.0 3 P36543 1 +Abnormal cutaneous elastic fiber morphology 0.6066986161433254 0.5226494003900755 0.601218256283856 1.0 1.0 3 P36543 1 +Portal fibrosis 0.5185606090682223 0.5175897015868371 0.6047445685887056 1.0 1.0 4 P55263 1 +Fatiguable weakness of proximal limb muscles 0.4686402487941103 0.5168187674923053 0.6052826777321858 1.0 1.0 5 Q92734 1 +Abnormal insulin level 0.3645353479690165 0.5135406043043527 0.6075732152773812 1.0 1.0 23 O75431,P53985,Q16836,O75844 4 +Breast carcinoma 0.3548158657377634 0.5126463730306516 0.6081987085632861 1.0 1.0 19 P48735,P46100 2 +Exercise induced muscle cramps 0.4687801737454071 0.5120407087262133 0.6086225191235886 1.0 1.0 6 P23786 1 +Abnormal intraocular pressure 0.4683369106514679 0.5103325776129276 0.6098184830845672 1.0 1.0 6 P04439,O75533,Q15043,Q99496 4 +Hypoplastic fingernail 0.3719225045235947 0.5096831545046795 0.6102734565345971 1.0 1.0 15 O75431,Q969G3,Q92785,Q14739,O60826,P48651 6 +Abnormal posterior segment imaging 0.6021530301366307 0.5083200858403959 0.6112288861258162 1.0 1.0 3 P04439 1 +Chorea 0.2831539455821396 0.5064931844304285 0.6125104730704973 1.0 1.0 86 Q9H6K4,Q9HD42,P10809,P07602,O14936,Q9BPX6,P35637,Q9BWD1,P00846,Q96N66,Q01105,Q9P0J0,P17480,P03915,Q08J23 15 +Sagittal craniosynostosis 0.5152649479214004 0.5062341684545748 0.6126922710924791 1.0 1.0 4 P61978 1 +Angina pectoris 0.6012652128345499 0.5055373301834034 0.6131814859550997 1.0 1.0 3 O75844 1 +Lateral clavicle hook 0.7909328114807567 0.5052700457910831 0.6133691785390218 1.0 1.0 2 Q9Y5S9 1 +Mandibular aplasia 0.7909328114807542 0.5052700457910768 0.6133691785390263 1.0 1.0 2 P53701 1 +Aplastic clavicle 0.7909328114807486 0.5052700457910607 0.6133691785390376 1.0 1.0 2 P48651 1 +Breast aplasia 0.7909328114807483 0.5052700457910607 0.6133691785390376 1.0 1.0 2 P02545 1 +Ascending tubular aorta aneurysm 0.5149415558854649 0.505124193180544 0.6134716099257722 1.0 1.0 4 O75844 1 +Wide anterior fontanel 0.3608987189841507 0.5047769803848183 0.6137154856899019 1.0 1.0 22 Q16134,Q32P28,P40855,O75381,O75718,P56589,Q08J23 7 +Papillary renal cell carcinoma 0.4641303898899615 0.4998954485269472 0.6171486972731361 1.0 1.0 5 Q92733,P02545 2 +Tongue nodules 0.7889758643183153 0.4998561693643272 0.6171763566528377 1.0 1.0 2 P98175 1 +Prominent ear helix 0.5132863624817208 0.4994553147437062 0.6174586592489562 1.0 1.0 4 P02545,O75844 2 +Abnormal nasal base 0.3959139175495285 0.4953242869632285 0.620371229789378 1.0 1.0 11 Q92785,Q969G3,Q13868,Q8TAQ2 4 +Abnormal urine ph 0.3802613025100316 0.4939588012209971 0.6213352757394606 1.0 1.0 43 P48735,P23786,O96000,Q16836,P00846,Q9BQT8,P03915,O43772 8 +Hamartoma 0.356153078760679 0.49367769314479 0.6215338215034194 1.0 1.0 17 P48735,O43924,P11802,P21912,O75874,P20585 6 +Abnormal number of permanent teeth 0.7866927592954963 0.4935695333443181 0.6216102217771291 1.0 1.0 2 Q14696 1 +Agenesis of lateral incisor 0.7866927592954962 0.4935695333443181 0.6216102217771291 1.0 1.0 2 P41227 1 +Right ventricular hypertrophy 0.5966770542256378 0.4912414505493992 0.6232556850774462 1.0 1.0 3 Q15233 1 +Aplasia hypoplasia of the nasal bone 0.5964269159856477 0.4904662217037732 0.6238040265152283 1.0 1.0 3 O14974 1 +Nausea and vomiting 0.3256949719574644 0.4893611464400801 0.6245860381536574 1.0 1.0 141 P00403,Q96CV9,Q9Y6M9,P42892,Q9NSD9,O96000,P61978,O43676,P00846,Q8IZA0,Q92804,Q15165,Q13423,P23786,Q9Y584,P22695,Q969G3,P03915,Q96CU9,Q86Y39,P07602,Q2TAA5,Q8N183,P50995,P35637,Q16836,P46100,Q16134 28 +Lumbar hyperlordosis 0.3553047967984821 0.4887705735166478 0.6250041333090071 1.0 1.0 17 Q96HY6,Q9Y5P6,P06753 3 +Head tremor 0.3788176438026186 0.4887589551649159 0.625012359713522 1.0 1.0 13 P20700,P35637,Q9Y4W6 3 +Tetraparesis 0.3776486415504491 0.4875274151769538 0.6258846195896373 1.0 1.0 35 P00846,P35637,Q9UBX3,P07602 4 +Ovoid vertebral bodies 0.4435730995182022 0.4852595177207413 0.6274922677694676 1.0 1.0 7 P54802,P15586 2 +Olivopontocerebellar hypoplasia 0.5941272430668669 0.4833595497589941 0.6288404641621512 1.0 1.0 3 P30153,Q9Y5P6 2 +Encephalopathy 0.2986774609389876 0.4807232388736169 0.630713212441631 1.0 1.0 107 Q5U5X0,Q86Y39,P07602,P23786,P00403,O96000,Q8N183,Q16836,O43676,Q9Y6M9,Q15067,Q96F07,P03915,O43772,Q96CU9 15 +Exodeviation 0.3611274119449051 0.4795362957671646 0.6315571535947531 1.0 1.0 24 Q15233,Q5U5X0,P98172,P46100 4 +Cerebral hemorrhage 0.3814442949175927 0.478935704029276 0.6319843699035772 1.0 1.0 12 P23786 1 +Limitation of joint mobility 0.288465030258079 0.4765023466072401 0.6337165359620673 1.0 1.0 95 O75431,P06753,P54802,Q9H6K4,O75844,P37268,P15586,Q8TD16,O75874,P51648,P48735,P23786,P50402,Q7LGA3,P16435,P02545,Q96AY3,P48651,O14979,Q9BX10,P46100,O14974,Q8WVM7 23 +Dermal translucency 0.4414013797713794 0.4763797031233407 0.6338038920092457 1.0 1.0 7 O75844 1 +Memory impairment 0.3758691073634097 0.4757328117210006 0.6342647418598024 1.0 1.0 35 P00403,P03915,P07602 3 +High anterior hairline 0.365653329020615 0.4756680798438136 0.6343108651006377 1.0 1.0 15 O96028,Q7LGA3,Q8N3U4,P98172 4 +Morphological abnormality of the corticospinal tract 0.3651114030490676 0.4727537202615996 0.6363888954184898 1.0 1.0 15 P00846 1 +Postaxial hand polydactyly 0.4010751291529597 0.4693521520560325 0.6388179433919197 1.0 1.0 10 O00459,Q14739,O43924,Q10713 4 +Impacted tooth 0.5891822401236583 0.4682053070024906 0.639637777387636 1.0 1.0 3 O75844 1 +Limitation of movement at ankles 0.5891822401236583 0.4682053070024906 0.639637777387636 1.0 1.0 3 O75844 1 +Abnormal csf metabolite level 0.3564350148486661 0.467512393875368 0.6401333269201115 1.0 1.0 59 Q86Y39,Q8N183,P00403,O96000,O43676,O95831,P00846,Q8NI60,Q9Y6M9,P03915,Q96CU9 11 +Abnormal pericardium morphology 0.3898469039881851 0.466224634536795 0.6410547179607478 1.0 1.0 11 P14174,P49748,P02545,Q14108,O15460 5 +Misalignment of incisors 0.4563212644616005 0.4646345357668686 0.6421931960365121 1.0 1.0 6 P46100 1 +Short palpebral fissure 0.3643007308094156 0.464177838077094 0.6425203378472837 1.0 1.0 27 P55795,O75844,Q14004,Q03164,O14974,P02545,P98175 7 +Anteriorly placed anus 0.3999229412875146 0.4640212030219293 0.6426325546876479 1.0 1.0 10 P53701,P49748,P16435,P62070,Q6NUK1,P48651 6 +Pericardial effusion 0.4559233402250455 0.4631419619759564 0.6432626138779562 1.0 1.0 6 P02545,P49748,Q14108 3 +Abnormal anatomic location of the heart 0.4095241600402727 0.4617472106796299 0.6442626110810581 1.0 1.0 9 Q10713,O75844 2 +Contractures involving the joints of the feet 0.348678776342984 0.46012106436173 0.6454293252724805 1.0 1.0 20 P50402,Q8TD16,P02545,Q8IZA0,Q08J23 5 +Visual loss 0.3702906921593976 0.4567695901069515 0.6478366656101286 1.0 1.0 50 P00403,P00846,P03915,Q10713 4 +Optic disc pallor 0.3710228550140462 0.4543736699841317 0.6495599001043151 1.0 1.0 49 Q9H6K4,Q5U5X0,Q86Y39,Q96CU9,Q8N183,O96000,O43676,O95831,P00846,Q9H061,Q9Y6M9,Q9BUK6,Q10713,Q6P4Q7 14 +Abnormal delivery 0.3497192239800029 0.451421522053359 0.6516857746316695 1.0 1.0 21 Q9Y619,O75844,Q9Y487,P06753,P02545,O75718 6 +Entropion 0.3968184459702708 0.449731586554928 0.6529039928305582 1.0 1.0 10 P02545,O75844 2 +Abnormal circulating proline concentration 0.7703848662752658 0.4496245753727123 0.6529811648380806 1.0 1.0 2 O96000 1 +Thin skin 0.3557999903332063 0.4470738664824407 0.6548217273456358 1.0 1.0 24 O75431,O75844,Q13126,P02545,P17252 5 +Abnormal circulating estrogen level 0.3852793224609705 0.4446067682114096 0.6566039554416236 1.0 1.0 11 Q969G3,P04637,P16435,Q99496 4 +Orofacial dyskinesia 0.4508553014873271 0.4442556916504946 0.6568577318014654 1.0 1.0 6 P49959,Q9BPX6 2 +Posteriorly rotated ears 0.2906975652176746 0.4413091974764591 0.6589891684984526 1.0 1.0 101 Q4J6C6,Q15392,P23786,Q14004,P46100,P98175,Q8NAT1,O75381,P42892,P56589,Q10713 11 +Abnormal aldolase level 0.4473749080699148 0.438575727803692 0.6609689875565019 1.0 1.0 5 Q8NAT1 1 +Telecanthus 0.3722641851729773 0.4382999119101869 0.6611688897819947 1.0 1.0 39 O00459,O75844,P21964,O15344,Q03164,P98172,P46100,Q96EK5,P02545,Q00577,Q16134,Q86XL3,Q08J23 13 +Stillbirth 0.383509357313943 0.4363001701510657 0.6626189584338755 1.0 1.0 11 P02545,P49454,P16435,O75844 4 +Subcapsular cataract 0.4466827719455315 0.436099064866055 0.6627648556201116 1.0 1.0 5 Q9H6K4,Q8N2K0 2 +Raynaud phenomenon 0.448422455141089 0.4352729222690493 0.6633643369768949 1.0 1.0 6 P02545,O75844 2 +Focal t2 hyperintense brainstem lesion 0.3417183266367725 0.4345356877411048 0.6638994852278182 1.0 1.0 19 Q86Y39,O96000,O43676,Q9Y6M9,Q96CU9 5 +Abnormal parotid gland morphology 0.7645140247879889 0.4342338630065968 0.6641186250705537 1.0 1.0 2 Q13428 1 +Tachycardia 0.3556438203848178 0.4338113852261851 0.664425413291923 1.0 1.0 25 P42892,O43772 2 +Abnormal femoral head morphology 0.338600473185957 0.4324188766430807 0.6654370009951804 1.0 1.0 18 O75431,O95831 2 +Axonal regeneration 0.4927071482661205 0.4307911979237566 0.6666202002524428 1.0 1.0 4 P07196 1 +Supraventricular tachycardia 0.4470717117862995 0.4303095701899252 0.6669704664052436 1.0 1.0 6 P02545,P41227 2 +Metaphyseal irregularity 0.4018742933547833 0.4277027594799643 0.6688675405880724 1.0 1.0 9 Q96HY6 1 +Hypertrophic cardiomyopathy 0.2928718893735468 0.4273682736503408 0.6691111119215858 1.0 1.0 105 P00403,P54802,Q9P0J0,Q9Y6M9,O96000,P15586,O43676,P00846,Q13423,Q9Y276,P50402,P34897,P02545,P03915,Q9H061,Q96CU9,Q86Y39,Q8N183,Q16836 19 +Truncal titubation 0.7612524461839484 0.4257858194969603 0.6702639208115246 1.0 1.0 2 Q5T8D3 1 +Primary peritoneal carcinoma 0.4903889994090256 0.4232814140902864 0.6720899529472346 1.0 1.0 4 P49959,P04637 2 +Bowing of the legs 0.3690964617946174 0.4196314790220763 0.6747546884404119 1.0 1.0 45 O75431,Q9NR77,P46100,Q13126,Q32P28,P17252,Q96HY6 7 +Hyporeflexia 0.3016635725979587 0.4170927009728058 0.6766106035388415 1.0 1.0 117 P06753,P54802,Q15067,Q9NR77,P35610,O95831,P00846,Q8NAT1,Q96F07,Q10713,P02545,P03915,Q9BUK6,O14979,P07602,Q9NSE4,P41440,P35637,Q96BR5 19 +Abnormal retinal artery morphology 0.3462595142335963 0.4167153004558224 0.6768866615895721 1.0 1.0 22 P00846,P03915 2 +Abnormal nerve conduction velocity 0.3692785428535344 0.4157527887005762 0.6775909088416521 1.0 1.0 42 O15121,O95831,Q9NR77 3 +Osteolysis involving bones of the upper limbs 0.4081494064583481 0.4140525306840298 0.6788356361209049 1.0 1.0 8 O75431,O75844 2 +Abnormal levels of alpha fetoprotein 0.4874451413701454 0.4138146041257879 0.6790098877142339 1.0 1.0 4 P35222,Q9NWH9 2 +Epiphyseal stippling 0.3674877778739845 0.4112750100233952 0.6808708916294686 1.0 1.0 12 P56589,P40855,O75381 3 +Neurofibromas 0.4248724337310535 0.4102365705280768 0.6816324164989844 1.0 1.0 7 P21912,Q969G3,Q07954 3 +Abnormality of the tongue 0.2756591300877822 0.4097161538455636 0.682014178787071 1.0 1.0 86 O75431,Q96CV9,P16278,P07196,Q03252,Q13428,O75844,P61978,O95831,P40855,O75381,P56589,Q10713,Q7LGA3,P02545,Q969G3,P48651,P46100,P98175,Q9BQT8,O60826,P20700 22 +Transient ischemic attack 0.4070165280650732 0.40922902851777 0.6823715932876226 1.0 1.0 8 P02545,P18583,P04637,O75844 4 +Hamartomatous polyposis 0.754729288975855 0.4091144165639586 0.6824556969408797 1.0 1.0 2 P20585 1 +Chorioretinal coloboma 0.4244060039400925 0.4084095497811657 0.682973023478036 1.0 1.0 7 Q10713,O60826,O14936 3 +Slow saccadic eye movements 0.3875565953886599 0.407780026477847 0.6834351787065565 1.0 1.0 10 P34897,Q8IV08 2 +Abnormal head movements 0.3768097032822294 0.4052335543805692 0.6853058427036143 1.0 1.0 11 P20700,P35637 2 +Distal sensory impairment 0.3674582028920051 0.4044089469788334 0.6859120220525063 1.0 1.0 40 Q9NSE4,Q9NR77,Q92734,P54802,Q96BR5,O95831,P02545,Q9BUK6 8 +Abnormal subarachnoid space morphology 0.3606266052384309 0.4040482770668006 0.6861772186494979 1.0 1.0 31 P00403,P03915,Q2TAA5,O95831 4 +Abnormality of the calf 0.356468458558272 0.4032135169200134 0.6867911567482974 1.0 1.0 55 O75431,Q9NR77,P46100,O95831,Q13126,Q32P28,P17252,Q96HY6 8 +Joint contracture of the hand 0.3670790814855244 0.4029349638100943 0.6869960692289019 1.0 1.0 44 Q15392,Q9NR77,P06753,O75844,P41227,Q99567,P98172,P16435,P02545,Q8IZA0,P07196,P42892,Q9Y6X9 13 +Skin dimple 0.3437817558181916 0.4022023989829646 0.6875350768419346 1.0 1.0 22 O95202,P53701,O96028,P62258,Q03164,P61978,Q9H3P2,Q8TAA9,P49366,Q969X5,Q08J23 11 +Motor axonal neuropathy 0.3557555722956483 0.3967871330420288 0.6915244398760858 1.0 1.0 14 P22626,O95831 2 +External ear malformation 0.3444099637165991 0.393188699447217 0.6941801155229079 1.0 1.0 16 P56589,Q00577,P40855,O75381 4 +Lymphoma 0.3507424502502764 0.3927665115091638 0.6944919409515409 1.0 1.0 26 P00813 1 +Abnormality of the metaphysis 0.3647586688696977 0.3922860527471498 0.6948468677617496 1.0 1.0 46 P48735,P00813,O95831,Q13126,Q96HY6 5 +Abnormal acetabulum morphology 0.3381433045668232 0.3920835920154779 0.694996450568161 1.0 1.0 17 Q96AY3,Q9Y584 2 +Pseudoepiphyses of the metacarpals 0.5631128718000459 0.3914065665412383 0.6954967393162663 1.0 1.0 3 O96028 1 +Pseudoepiphyses of hand bones 0.5631128718000459 0.3914065665412383 0.6954967393162663 1.0 1.0 3 O96028 1 +Pseudoepiphyses 0.5631128718000459 0.3914065665412383 0.6954967393162663 1.0 1.0 3 O96028 1 +Abnormality of chromosome stability 0.3631183117988891 0.3906703201521094 0.6960409399150669 1.0 1.0 12 Q969G3 1 +Myoglobinuria 0.3932943988136043 0.3903134314701823 0.6963047925135519 1.0 1.0 9 P23786 1 +Postural instability 0.3309319898908696 0.3884035923458682 0.6977173861927881 1.0 1.0 18 Q9NR77 1 +Skin ulcer 0.353524089561557 0.3879560990624752 0.6980485219296226 1.0 1.0 28 Q03519,Q8IZA0,P48735 3 +Neoplasm of the peripheral nervous system 0.3307082446207414 0.3871372341428322 0.6986546137850431 1.0 1.0 18 Q99496,P46100,P02545,P21912,Q02978,Q969G3,Q07954 7 +Foot dorsiflexor weakness 0.3578160936534498 0.3867161703097528 0.6989663436356617 1.0 1.0 31 P31483,Q9NR77,P06753,Q14739,Q96BR5,P02545,Q9BQT8,P07196,Q9Y6X9 9 +Bulbar palsy 0.3823849644523642 0.384828998937505 0.7003641125839166 1.0 1.0 10 P35637,P06753 2 +Arthrogryposis multiplex congenita 0.3609041674566904 0.3846407876028273 0.7005035706046252 1.0 1.0 34 Q9HD42,Q15392,O75844,P06753,Q99567,Q8TD16,P02545,Q96AY3,Q969X5,Q9UPT5 10 +Abnormality of iron homeostasis 0.4309687467184778 0.3811918041827118 0.703060930169753 1.0 1.0 5 P28288 1 +Atopic dermatitis 0.4306235716617667 0.3800154508976066 0.7039339458641725 1.0 1.0 5 Q9Y6X9,O95394,Q8TD19,P62070 4 +Pigmentary retinopathy 0.3638478538211979 0.3788293113660326 0.7048146195327183 1.0 1.0 42 Q8N183,P00403,Q16836,P00846,Q15067,P03915,Q9BUK6,Q96CU9 8 +Emphysema 0.3904942807714714 0.3783060867120158 0.7052032243008255 1.0 1.0 9 Q03519,Q9NSD9 2 +Posterior embryotoxon 0.3351440823200923 0.3757450615779876 0.7071064342211786 1.0 1.0 17 P21964,Q7LGA3,P40855,O75381,P56589 5 +Aplasia hypoplasia involving forearm bones 0.3350738334102096 0.3753645531264011 0.7073893633178221 1.0 1.0 17 Q96AY3 1 +Areflexia 0.2712345587818313 0.3752630947420174 0.7074648100687804 1.0 1.0 84 Q9H6K4,P41440,Q9NR77,Q92734,P06753,P61978,Q9H173,O95831,Q13217,P02545,Q8TD16,Q8NAT1,O75477,Q9BQT8,P07196,Q15067,P56589,O95721 18 +Bone pain 0.3340245056238738 0.3748675302148861 0.7077589882300881 1.0 1.0 20 P48735,P07602,Q6UN15,Q14108,O75874,P53680 6 +Adrenocorticotropic hormone deficiency 0.7407045009784676 0.3743215477086157 0.7081651026887681 1.0 1.0 2 O00170 1 +Megalocornea 0.3698043564624976 0.3734237138628697 0.7088331127736898 1.0 1.0 11 O95202,O96028,Q9H3P2,Q96EK5,Q9Y5P6 5 +Abnormal protein o linked glycosylation 0.4742616527801901 0.3724232549488727 0.7095777422419007 1.0 1.0 4 Q8N511 1 +Bilateral cleft palate 0.7397260273972563 0.3719492979794391 0.7099305995902336 1.0 1.0 2 Q12959 1 +Non midline cleft palate 0.7397260273972563 0.3719492979794391 0.7099305995902336 1.0 1.0 2 Q12959 1 +Abnormal metatarsal morphology 0.338529736960902 0.3718572481297807 0.7099991372176095 1.0 1.0 22 Q15392,O96028,P16435,Q8NAT1,Q08J23,Q03252 6 +Aplasia hypoplasia of the radius 0.3402236025735817 0.371173941189141 0.7105079809046901 1.0 1.0 16 Q96AY3 1 +Abnormality of pain sensation 0.3450688358481872 0.3710346082030221 0.7106117549720947 1.0 1.0 25 O95831,Q9NR77 2 +Preaxial foot polydactyly 0.7387475538160382 0.3695843986527201 0.7116921773669467 1.0 1.0 2 O96028 1 +Rieger anomaly 0.7387475538160382 0.3695843986527201 0.7116921773669467 1.0 1.0 2 O96028 1 +Ectopia pupillae 0.7387475538160382 0.3695843986527201 0.7116921773669467 1.0 1.0 2 O96028 1 +Malrotation of small bowel 0.7387475538160382 0.3695843986527201 0.7116921773669467 1.0 1.0 2 O96028 1 +Craniofacial asymmetry 0.7387475538160382 0.3695843986527201 0.7116921773669467 1.0 1.0 2 O96028 1 +Mitral stenosis 0.5547004638507523 0.3678271187770874 0.713002146607193 1.0 1.0 3 O75844 1 +Aortic valve calcification 0.5547004638507523 0.3678271187770874 0.713002146607193 1.0 1.0 3 O75844 1 +Fatigable weakness of skeletal muscles 0.396786350775053 0.3663370441299621 0.714113590703559 1.0 1.0 8 Q92734,P06753 2 +Spinal rigidity 0.3534107325461658 0.3636696479891705 0.7161047109882681 1.0 1.0 13 Q5JTV8,P06753,P02545,P50402 4 +Simplified gyral pattern 0.3491269490584594 0.3617500688404577 0.7175388078149052 1.0 1.0 28 Q86XL3,Q969G3,P20700,Q9UPT5,Q03252 5 +Abnormal diaphysis morphology 0.339171287140704 0.3594161986842352 0.7192837584267906 1.0 1.0 61 O75431,Q9NR77,Q7LGA3,P46100,Q13126,Q32P28,Q96AY3,P17252,O75718,Q96HY6,P48651 11 +Mucosal telangiectasiae 0.385970194527731 0.3591206168427387 0.7195048589618072 1.0 1.0 9 Q8IZA0,P10619 2 +Abnormality of bladder morphology 0.3855876578904718 0.3575108581405161 0.7207093989755695 1.0 1.0 9 Q9NWM8 1 +Bowing of the arm 0.469200885946579 0.3569917783314333 0.7210979606982164 1.0 1.0 4 Q32P28 1 +Abnormality of metacarpophalangeal joint 0.4681110544452176 0.3537032596470327 0.7235612794812243 1.0 1.0 4 Q15233 1 +Abnormality of the peripheral nervous system 0.2785564455581766 0.350860924965252 0.7256926874972942 1.0 1.0 95 P07602,Q9NR77,P41440,O15121,P46100,O95831,P42892,Q10713 8 +Spastic tetraparesis 0.3390838713174357 0.3487740968519958 0.7272589114655452 1.0 1.0 24 P00846,Q5U5X0,P07602 3 +Abnormal activity of mitochondrial respiratory chain 0.3535119359655037 0.347846997317642 0.7279550922884626 1.0 1.0 52 Q86Y39,Q70HW3,Q8N183,O96000,O43676,Q9Y584,Q9Y6M9,Q9Y2R0,Q9UBX3,Q96CU9 10 +Emotional lability 0.3507397159818329 0.3466878954442262 0.7288258049222325 1.0 1.0 54 P07602,Q8N183,P50995,Q96CV9,P35637,P17252,Q9P0J0,Q92804,Q969G3,Q15165,P09651,Q96CU9 12 +Abnormality of retinal pigmentation 0.3183841347407645 0.3459889747440091 0.7293510005208275 1.0 1.0 68 Q96CU9,Q8N183,P00403,Q16836,P00846,P02545,P40855,Q9P0J0,Q15067,P56589,P03915,Q9BUK6,O75381,Q6P4Q7 14 +Central hypothyroidism 0.3732958717013006 0.3453896866435181 0.7298014295510622 1.0 1.0 10 O00170,Q8N3U4,Q99496,Q969G3 4 +Narrow palpebral fissure 0.3494772825079635 0.3452346333664206 0.7299179838422951 1.0 1.0 13 P38159 1 +Renal tubular dysfunction 0.3580835316573754 0.3449685051205328 0.7301180482629988 1.0 1.0 39 Q86Y39,Q8N183,P00403,O96000,O43676,Q16134,P40855,Q9Y6M9,P03915,Q96CU9 10 +Abnormal brainstem morphology 0.2729545035192526 0.3436516656396499 0.7311082648343437 1.0 1.0 89 Q86Y39,Q8N183,O96000,O15121,O43676,O95831,Q96EK5,Q13217,Q9Y6M9,Q969G3,P20700,Q9UPT5,Q10713,Q96CU9 14 +Ectropion of lower eyelids 0.7270058708414853 0.3417890444015397 0.7325096549200221 1.0 1.0 2 O60716 1 +Distal sensory impairment of all modalities 0.4188703885079991 0.3407799856165188 0.7332692187260754 1.0 1.0 5 P19367,O15270,O15269,P48643 4 +Absent brainstem auditory responses 0.463647743742839 0.3403663500652358 0.7335806562880198 1.0 1.0 4 P07196 1 +Osteomalacia 0.4635406412467826 0.3400489308516588 0.7338196796664529 1.0 1.0 4 P53680 1 +Osteoarthritis 0.3517749099838982 0.338621333818388 0.7348950090744721 1.0 1.0 12 O75844,P02545,Q14108,Q96HY6,P35670 5 +Colpocephaly 0.4058489895947751 0.337693265678299 0.7355943501652085 1.0 1.0 7 Q8N3U4,O14974 2 +Dyscalculia 0.3806300870548664 0.3368308094655269 0.7362444462395914 1.0 1.0 9 P35637,P22626 2 +Cough 0.3410853452511995 0.3363910408857612 0.7365760045909082 1.0 1.0 26 P41440,Q92734,Q6UN15,Q9NR77,Q9NSD9 5 +Focal dystonia 0.3267984919698769 0.3344838747110727 0.7380144570161016 1.0 1.0 20 P35637,Q15043,Q13428 3 +Abnormal forearm bone morphology 0.3268038883606609 0.3313009620558552 0.7404171646874205 1.0 1.0 17 Q32P28 1 +Telangiectasia of the skin 0.3266646527646759 0.3305719434295521 0.7409678416937839 1.0 1.0 17 Q8IZA0 1 +Ambiguous genitalia 0.3205052354543519 0.3305588250125218 0.7409777521366265 1.0 1.0 18 Q15392 1 +Limb undergrowth 0.3546376492088744 0.3293423113188168 0.7418969664725419 1.0 1.0 48 P48735,Q15392,Q03164,P98172,P98175,P17252,O75874,Q96HY6 8 +Dementia 0.3530478212009806 0.329187401428487 0.7420140449630364 1.0 1.0 50 P22626,P07602,Q9Y487,P00403,P36543,P35637,P03915,P00846,Q9UBB4,O15118,Q14108,P09651,P20700,P35670 14 +Abnormality of complement system 0.4589469311182291 0.3265521039784892 0.7440066745393576 1.0 1.0 4 Q03252 1 +Neurogenic bladder 0.4175469621979731 0.3265378417137691 0.7440174633555123 1.0 1.0 6 Q8TAA9,P56589,P50336 3 +Supernumerary spleens 0.4009432107611445 0.3196898206990602 0.7492034770666831 1.0 1.0 7 Q15904,P49454 2 +Aphasia 0.3520967108232098 0.3189531314497448 0.7497620536235983 1.0 1.0 36 P22626,P00403,Q7LGA3,P21964,P46100,P09651,P17480,P03915,Q13428 9 +Abnormal eating behavior 0.3210321175957386 0.3179644286433273 0.7505119195313286 1.0 1.0 19 Q4J6C6,P35610,Q92785,P49366,Q969G3 5 +Joint stiffness 0.3467817859121906 0.3167711307661423 0.7514172712599736 1.0 1.0 54 O75431,P48735,Q9BX10,O75844,P50402,P54802,P15586,P46100,P16435,O14974,P02545,Q96AY3,O75874,P51648 14 +Elevated urinary carboxylic acid 0.4145782920249247 0.3166509614738753 0.7515084623523429 1.0 1.0 6 O96000,P50336,P36551 3 +Metaphyseal widening 0.3179067174132626 0.3165357279100764 0.7515959112006942 1.0 1.0 18 O95831 1 +Hepatic necrosis 0.3754810566810305 0.315722407526155 0.7522132172548961 1.0 1.0 9 Q16134,P49748,Q16836 3 +Absence of subcutaneous fat 0.3995909880610483 0.3147819095473445 0.7529272480930593 1.0 1.0 7 O75844 1 +Decreased circulating acth level 0.4139538284438969 0.3145850688014411 0.7530767173604045 1.0 1.0 6 O00170,Q969G3 2 +Exercise induced myalgia 0.3658021017732367 0.3137998655008612 0.753673046544487 1.0 1.0 10 P23786 1 +Unilateral renal agenesis 0.3232166692872181 0.3126610491409193 0.7545381911441242 1.0 1.0 17 Q86XL3 1 +Airway obstruction 0.3285428960651012 0.311627282672907 0.7553237974576588 1.0 1.0 16 P21964,P02545,Q96HY6,O75844 4 +Attenuation of retinal blood vessels 0.4127710024121664 0.3106852854255318 0.7560398845879266 1.0 1.0 6 P04439,O43837 2 +Minimal change glomerulonephritis 0.3454004328289378 0.3103608475948718 0.7562865641780971 1.0 1.0 12 Q8NFH4,O43707,Q9BW27,Q8WUM0,Q14C86,Q8N1F7,Q12769 7 +Peritonitis 0.3454004328289378 0.3103608475948718 0.7562865641780971 1.0 1.0 12 Q8NFH4,O43707,Q9BW27,Q8WUM0,Q14C86,Q8N1F7,Q12769 7 +Polydactyly 0.352656816011313 0.3046859977120553 0.7606053150712144 1.0 1.0 43 O00459,O43924,P21964,O96028,P61978,P98172,P49454,P98175,Q00577,O60826,P17252,Q14739,Q15067,Q8N3U4,Q9Y2V7,Q10713 16 +Hyperintensity of cerebral white matter on mri 0.3206782036284746 0.3012447776898806 0.76322784704227 1.0 1.0 20 P17480,P07602,P20700,Q9BUK6 4 +Hypochromic anemia 0.3397014950649836 0.3006665570128544 0.7636687730453071 1.0 1.0 13 P46100 1 +Vitritis 0.5287198929118653 0.2991450303309131 0.76482938921381 1.0 1.0 3 P04439 1 +Emg chronic denervation signs 0.3353325499351912 0.298802309825564 0.7650908884276053 1.0 1.0 14 P22626,P07602 2 +Laryngomalacia 0.3307203321185702 0.2980064029128851 0.7656982767206204 1.0 1.0 15 P21964,P02545,P07602,P16435 4 +Rhizomelia 0.3610882834077607 0.2943890087979576 0.7684606647076582 1.0 1.0 10 Q03164,Q15392 2 +Heterogeneous 0.3493997534689369 0.2902351983152853 0.771636310174991 1.0 1.0 39 Q9Y619,O75844,P21964,P06753,Q9NR77,O15344,Q16836,P46100,P00846,P02545,P07196,Q9Y3D3,P11717,P03915 14 +Abnormal circulating aromatic amino acid concentration 0.4458224543081001 0.2893004932638366 0.7723514348787293 1.0 1.0 4 P61457,Q9UJS0,P09417 3 +Abnormal vitreous humor morphology 0.3774552885298958 0.2889247824947795 0.7726389384262671 1.0 1.0 8 P04439,Q99496,P53701,P35222,O75533 5 +Congenital contracture 0.3495347872191986 0.2883440949346039 0.7730833568724202 1.0 1.0 40 Q9HD42,Q15392,O75844,P06753,Q99567,Q8TD16,P02545,Q96AY3,Q9Y6X9,Q96A33,Q969X5,Q9UPT5 12 +Abnormal vertebral morphology 0.2782227133694832 0.2862130444383107 0.7747149534556521 1.0 1.0 101 P48735,P00813,P54802,P61978,P46100,O95831,Q32P28,Q96AY3,Q96HY6,Q10713 10 +Childhood onset sensorineural hearing impairment 0.7015655577299258 0.2854295366010263 0.7753150813462331 1.0 1.0 2 Q9NSE4 1 +Prelingual sensorineural hearing impairment 0.7015655577299258 0.2854295366010263 0.7753150813462331 1.0 1.0 2 Q9NSE4 1 +Hyperinsulinemic hypoglycemia 0.3909893946321937 0.2841366717296376 0.7763056446159466 1.0 1.0 7 P53985 1 +Glomerulopathy 0.3672213863757932 0.282697227577219 0.7774089416693684 1.0 1.0 9 P02545,Q03252 2 +Paroxysmal involuntary eye movements 0.3194423191264974 0.2805005780379471 0.7790934820476081 1.0 1.0 21 Q86Y39,O96000,O43676,Q9Y6M9,Q96CU9 5 +Upper eyelid coloboma 0.6989562948466916 0.2799606727809474 0.7795076773918845 1.0 1.0 2 Q13428 1 +Absent nipple 0.6989562948466896 0.2799606727809425 0.7795076773918883 1.0 1.0 2 P10586 1 +Complete duplication of phalanx of hand 0.4423957824997465 0.2799062755323184 0.7795494124228883 1.0 1.0 4 P34897 1 +Abnormality of fibula morphology 0.3471375590406214 0.2758842539530025 0.7826369682793524 1.0 1.0 11 Q96HY6 1 +Small earlobe 0.3738225971158654 0.2749672676657447 0.7833413859471401 1.0 1.0 8 P98175,P10586 2 +Hepatic failure 0.3453608615091227 0.2749620627040755 0.7833453848426546 1.0 1.0 50 P23786,Q16836,P46100,P00846,O43772,O75381,P56589,P03915,Q10713 9 +Serositis 0.3154292178082614 0.2732593632964639 0.7846538503375546 1.0 1.0 17 Q8NFH4,P14174,O43707,Q9BW27,Q8WUM0,Q14C86,Q8N1F7,O15460,Q12769 9 +Bifid scrotum 0.4010478835071553 0.2730067975438212 0.7848479903138934 1.0 1.0 6 Q96EK5 1 +Aplasia hypoplasia of the patella 0.439705629920279 0.2726306775702329 0.7851371276484471 1.0 1.0 4 Q9Y5S9,Q96AY3 2 +Portal vein thrombosis 0.6950424005218458 0.2718692820461833 0.7857225312722784 1.0 1.0 2 Q9NWH9 1 +Epigastric pain 0.6950424005218458 0.2718692820461833 0.7857225312722784 1.0 1.0 2 Q9NWH9 1 +Splanchnic vein thrombosis 0.6950424005218458 0.2718692820461833 0.7857225312722784 1.0 1.0 2 Q9NWH9 1 +Sudden loss of visual acuity 0.6950424005218429 0.271869282046177 0.7857225312722833 1.0 1.0 2 O00170 1 +Retinal perforation 0.6950424005218391 0.2718692820461691 0.7857225312722893 1.0 1.0 2 P04439 1 +Open mouth 0.3368276852851706 0.2718151873751142 0.78576412690697 1.0 1.0 30 Q15233,P61978,P46100,Q00577,Q86XL3,Q10713 6 +Limb dystonia 0.3361439826668141 0.2707083187637695 0.7866153781923466 1.0 1.0 12 Q8N3U4,P35637 2 +Abnormality of the musculature of the lower limbs 0.3366054616194693 0.2705695602788086 0.7867221101723689 1.0 1.0 30 Q9BTV4,P50402,Q9NR77,P00846,P02545,Q8NAT1,P07196,O14979 8 +Back pain 0.3223127291525875 0.2690969797957445 0.7878550545176075 1.0 1.0 23 Q8WXH0,P50336,Q9BTV4,P50402,P02545,Q8TAA9,P36551,Q969G3,P04637,P35670 10 +Abnormal exteroceptive sensation 0.3451171816349639 0.2681782036185658 0.7885621516754671 1.0 1.0 49 Q9H6K4,P07602,Q9NR77,P54802,O95831 5 +Acetabular dysplasia 0.3632440858497875 0.2671812736507445 0.7893295936798319 1.0 1.0 9 Q9Y584,P16278 2 +Spinal canal stenosis 0.3859781229720458 0.2667585015398904 0.7896551076789746 1.0 1.0 7 O00170,Q9NSE4 2 +Difficulty running 0.3278854308004771 0.2651695254378314 0.7908788699830203 1.0 1.0 14 P06753,Q9BPX6,Q8TD16,P07196,Q9Y5P6 5 +Breech presentation 0.3614219009851127 0.2601601250583186 0.7947402610241254 1.0 1.0 9 Q9Y619,O75718,P06753 3 +Scleroderma 0.3923270191179605 0.2585800878524483 0.7959592484301552 1.0 1.0 5 P02545 1 +Eruption failure 0.3834615294521761 0.258168884425336 0.7962765707381354 1.0 1.0 7 O75844 1 +Abnormality of the peritoneum 0.3174051132733334 0.2577043924747035 0.7966350558797652 1.0 1.0 16 Q8NFH4,Q01844,O43707,Q9BW27,Q8WUM0,Q14C86,Q8N1F7,P04637,Q12769 9 +Abnormal muscle fiber alpha dystroglycan 0.6872146118721347 0.2560939659976886 0.7978782811022151 1.0 1.0 2 Q9Y5P6 1 +Calf muscle pseudohypertrophy 0.6872146118721347 0.2560939659976886 0.7978782811022151 1.0 1.0 2 Q9Y5P6 1 +Abnormal blood gas level 0.510848450995492 0.2558401769904725 0.7980742492854391 1.0 1.0 3 P06753 1 +Hypogonadotropic hypogonadism 0.3243923324750257 0.2557157037727028 0.7981703683850814 1.0 1.0 25 P00403,P03915 2 +Calcinosis 0.390852087243922 0.2542955394363829 0.7992672455813636 1.0 1.0 5 P02545,O75844 2 +Aplasia hypoplasia involving bones of the thorax 0.3364761142466058 0.2531051934531884 0.8001869257255028 1.0 1.0 32 O75431,O75844,P41227,Q03164,P98172,P16435,P02545,Q8TAA9,P98175,Q14739,O60826,Q96HY6,P48651 13 +Non midline cleft lip 0.4321148825065311 0.2525832322618752 0.8005902886758005 1.0 1.0 4 Q15427,Q9NXE4,O60716 3 +Neoplasm of the pancreas 0.3166828193640162 0.2525697323382256 0.8006007218988396 1.0 1.0 22 Q01844,Q99496,P78549,P11802,O95453,Q9NYB0,P04637 7 +Intracellular accumulation of autofluorescent lipopigment storage material 0.6852576647097064 0.2522358893975104 0.8008587389567172 1.0 1.0 2 O14773 1 +Peroneal muscle atrophy 0.5080924899137043 0.2494663599751431 0.803000059310744 1.0 1.0 3 Q9NR77 1 +Ankyloglossia 0.3663825135267723 0.247017253684858 0.8048948712517565 1.0 1.0 8 O75844 1 +Distal sensory loss of all modalities 0.4295039164490848 0.2458552744925751 0.8057942670556033 1.0 1.0 4 P19367,O15270,O15269 3 +Bird like facies 0.3796578143245115 0.2453652451068115 0.8061736369858719 1.0 1.0 7 O75844 1 +Decreased number of peripheral myelinated nerve fibers 0.3192743683925446 0.2451986567594782 0.8063026164000806 1.0 1.0 15 Q92734,P02545,P07196,Q9NR77 4 +Abnormal cranial nerve physiology 0.3012406105420657 0.245044461702102 0.8064220051248769 1.0 1.0 70 P48651,P48735,P07602,Q9NR77,P06753,Q969G3,Q92734,Q15043,P34897,P02545,Q86U42,P40855,O75381,P07196,P56589,O75874 16 +Bladder neoplasm 0.3793855525773495 0.2444571844775184 0.8068767579969298 1.0 1.0 7 P35222,P04637,P78549 3 +Abnormal consumption behavior 0.3124504701437593 0.2442105215547653 0.8070677787063578 1.0 1.0 21 Q4J6C6,P35610,Q8TAQ2,Q92785,P49366,Q8N5K1,Q969G3,O14497 8 +Lipoma 0.3915124619880408 0.2437280370899268 0.8074414576004338 1.0 1.0 6 Q8TAA9,Q9BUK6 2 +Abnormality of the wrist 0.3242476917761598 0.2435747219729283 0.807560207671413 1.0 1.0 26 Q9H6K4,Q9Y5S9,O75844,P16435,O95831,P02545,P16278 7 +Polycystic liver disease 0.5053833605220068 0.2432822522289202 0.8077867521166464 1.0 1.0 3 Q9UGP8,P14314 2 +Scapular winging 0.3173180142526904 0.2429752579731818 0.8080245644588075 1.0 1.0 23 Q9BTV4,P50402,P06753,Q8TD16,P02545,P07196,Q9Y5P6 7 +Tongue atrophy 0.3849035346994126 0.2373373852744722 0.812395061242879 1.0 1.0 5 P07196,Q9Y6X9 2 +Keratosis pilaris 0.5026950142515809 0.2372260492918918 0.8124814286040183 1.0 1.0 3 Q07954 1 +Impaired glucose tolerance 0.3848472003637631 0.2371792836843459 0.8125177070629055 1.0 1.0 5 P02545 1 +Constipation 0.2599713191618873 0.2370574359998553 0.8126122323952227 1.0 1.0 84 Q13423,Q9UGU0,P55795,P00403,Q7LGA3,Q03164,P61978,P21964,P46100,P37268,P42892,Q8N3U4,P20700,P03915,Q03252 15 +Abnormal peripheral nervous system morphology 0.3157658949798861 0.2357325620125364 0.813640201005208 1.0 1.0 156 P06753,P00403,Q15067,Q9NR77,O15121,O95831,P00846,O75381,P56589,P22626,Q8IV08,P02545,Q969G3,P03915,P48651,P07602,Q6DKK2,P41440,Q9BPX6,Q92734,P35637,Q96BR5,P46100,Q9BQT8,P17480,P20700,P09651 27 +Impaired vibratory sensation 0.3264627147522718 0.2341939402573123 0.8148344192000634 1.0 1.0 28 P00846,Q9NR77 2 +Short clavicles 0.3545027839234639 0.2340178383285687 0.8149711301483527 1.0 1.0 9 P02545,O75431,O75844 3 +Adrenal hyperplasia 0.3874662796557894 0.2316944825248986 0.8167753170973973 1.0 1.0 6 P17252 1 +Leukocytosis 0.3239909228547223 0.2314061172339539 0.8169993132601538 1.0 1.0 27 Q6UN15,P00813,O14936,Q03252 4 +Tube feeding 0.3227687373750757 0.2252932257700237 0.8217511692729191 1.0 1.0 61 Q15233,P07602,P06753,P37268,Q92734,P61978,O15121,P35637,Q96N66,Q01105,P17480,Q08J23 12 +Dental crowding 0.3108282387621955 0.2227692278992579 0.8237151187812692 1.0 1.0 22 Q15233,O75431,O75844,P06753,P36543,P02545,Q01105 7 +Preaxial polydactyly 0.3424872932937073 0.2215974292047574 0.8246272839413298 1.0 1.0 10 O43924,O96028,P49454,Q9H3P2 4 +Anophthalmia 0.3423432998410263 0.2210591952140449 0.8250463417663325 1.0 1.0 10 Q8NAT1,P53701 2 +Vocal cord paresis 0.418733681462136 0.2190364285198032 0.8266216708465697 1.0 1.0 4 P36776,P43243,Q8TB36 3 +Abnormal autonomic nervous system physiology 0.3267974085137881 0.2170115680961929 0.8281993297227939 1.0 1.0 30 P42892,P07602,P41440 3 +Encephalocele 0.3315176399210615 0.2142015666132566 0.8303898744543794 1.0 1.0 11 Q10713,Q13428 2 +Ankle flexion contracture 0.3158768545305519 0.2136201866812946 0.8308432560626036 1.0 1.0 14 Q5JTV8,Q96AY3 2 +Testicular atrophy 0.4164490861618848 0.2135447181572523 0.8309021133457803 1.0 1.0 4 Q9NX24,P00492,P04637 3 +Abnormal oral frenulum morphology 0.3154344510376838 0.2117880744374671 0.8322723727082555 1.0 1.0 14 P17252,O75844 2 +Paranoia 0.3753812015002282 0.2112945967952536 0.8326573988846613 1.0 1.0 5 P50336,P36551 2 +Type ii diabetes mellitus 0.3285811221346564 0.2097370078525166 0.8338729397998097 1.0 1.0 32 P00403,P02545,P03915 3 +Intestinal atresia 0.3299500337392699 0.2082894637045214 0.8350029579864593 1.0 1.0 11 P49454,O14974 2 +Myelofibrosis 0.4880180101188419 0.2056029867643018 0.8371010442727806 1.0 1.0 3 P04637 1 +Soft tissue sarcoma 0.3245685671386529 0.205245308600956 0.8373804717257953 1.0 1.0 30 Q13126,Q15392 2 +Abnormal enchondral ossification 0.3121666574147025 0.2046414896315297 0.8378522372860886 1.0 1.0 24 O96028,P40855,O75381,Q14739,P56589,Q96HY6 6 +Tapered finger 0.3331009138567286 0.2022416128698198 0.8397278428443233 1.0 1.0 37 Q9NSE4,P23786,Q06136,Q03164,P46100,Q96EK5,P42892,Q03252 8 +Pseudobulbar paralysis 0.3663148483429252 0.2022329147508404 0.8397346424558692 1.0 1.0 7 Q15233 1 +Aplasia hypoplasia of the eyebrow 0.3362508305217799 0.2019143888713429 0.839983653061622 1.0 1.0 43 O75431,Q9BX10,P00813,O75844,P41227,P61978,Q96EK5,P02545,Q00577,Q8WVM7,Q8N3U4,Q08J23,Q07954 13 +Proportionate short stature 0.3254995097101648 0.2014729750005386 0.8403287589824477 1.0 1.0 31 Q9Y619,Q15392,P53701,P10619,Q9H173,Q16836,Q5JRA6,P16278,Q14739,Q96HY6,P48651 11 +Talipes equinovarus 0.296381148969781 0.200296483214946 0.8412487128095831 1.0 1.0 70 Q9Y5S9,Q9Y619,Q8TB36,P06753,P21964,Q96A33,Q969X5,Q9NR77,P61978,Q8TD16,Q8NI60,Q15392,Q9Y487,P10412,P16435,Q8TAA9,Q96AY3,Q9HD42,Q9BX10,P36543,O96028,P46100,P98175,Q9NWM8 24 +Emg neuropathic changes 0.3110903050983915 0.1993087259074773 0.8420212538200071 1.0 1.0 24 P07602,Q9NR77 2 +Cutaneous photosensitivity 0.3085956857057954 0.1991087920285598 0.8421776438825563 1.0 1.0 23 Q15126,P37268,P22830,Q06136,Q14108,Q08J23 6 +Amelogenesis imperfecta 0.4088934639947077 0.1958855906435736 0.8446997157810494 1.0 1.0 4 Q6P4Q7 1 +Erythroid hyperplasia 0.4069843342036539 0.1915472757631 0.8480968454520295 1.0 1.0 4 O75533,P06132,Q86SX6 3 +Chronic axonal neuropathy 0.6513372472276523 0.1909530244309298 0.8485623969273104 1.0 1.0 2 P04792 1 +Abnormality of the basal ganglia 0.2568630650388557 0.1906503576486485 0.8487995340315915 1.0 1.0 85 P23786,P00403,O95831,P00846,Q96N66,Q8NI60,P03915 7 +Periventricular cysts 0.367299986604494 0.1902959352322114 0.8490772386711001 1.0 1.0 5 O96028,P11177 2 +Abnormal number of granulocyte precursors 0.6506849315068408 0.1898797333301924 0.8494033740056706 1.0 1.0 2 Q07020 1 +Neoplasm of the small intestine 0.3718750461040406 0.1876170348355292 0.8511768715145132 1.0 1.0 6 P02545,P78549 2 +Abnormality of head blood vessel 0.3108549589560578 0.1865841623917934 0.851986685252059 1.0 1.0 25 P07602,P10619,P21964,P00846,P03915,P48651 6 +Abnormal urine magnesium concentration 0.6480756686236052 0.1856267007106657 0.852737513325361 1.0 1.0 2 P05023 1 +Writer s cramp 0.6480756686236052 0.1856267007106657 0.852737513325361 1.0 1.0 2 Q9ULV3 1 +Hypocalciuria 0.6480756686235978 0.1856267007106538 0.8527375133253703 1.0 1.0 2 P53680 1 +Hypermagnesemia 0.6480756686235978 0.1856267007106538 0.8527375133253703 1.0 1.0 2 P53680 1 +Poor gross motor coordination 0.4765639327393117 0.1826561529270154 0.8550678217603795 1.0 1.0 3 Q9Y5P6 1 +Neoplasm of the breast 0.3120580997336818 0.1814263903186065 0.8560329061062717 1.0 1.0 26 P48735,P11802,P46100,P02545,O75874 5 +Abdominal aortic aneurysm 0.4017624020887808 0.1799394103407372 0.8572001351551792 1.0 1.0 4 O15460,P31153,Q96MF7 3 +Aortic dissection 0.4017624020887803 0.1799394103407364 0.8572001351551799 1.0 1.0 4 O15460,Q02809,P31153 3 +Spastic dysarthria 0.3467320261437931 0.1776538522470702 0.8589948291945433 1.0 1.0 8 O94905,Q9H2M9,Q96GW9,Q86SX6,Q9Y4W6,Q8WVX9,O14802 7 +Coarse hair 0.2937430405187254 0.1721448952307286 0.8633236182631068 1.0 1.0 17 Q9Y276,P36543,Q9Y487,P54802,P15586 5 +Anorexia 0.3074360087937503 0.1700315303161524 0.8649853400766871 1.0 1.0 25 Q13423,P46100,Q14108,Q6UN15 4 +Abnormality of the nasal tip 0.2674275512200074 0.1691538908621688 0.8656755968316887 1.0 1.0 100 O75431,O14936,P21964,P98172,Q13868,Q00577,P42892,Q9UGU0,O75844,Q03164,P61978,O95831,Q96EK5,P17252,Q8N3U4,P23786,Q7LGA3,P16435,P02545,P10586,Q969G3,P46100,P38159 23 +Pelvic girdle muscle weakness 0.3437364474660128 0.1676897090870487 0.8668273925058632 1.0 1.0 8 O14979 1 +Ophthalmoparesis 0.2793151456078768 0.1659497330884726 0.8681965087224002 1.0 1.0 74 Q5U5X0,Q9BPX6,P00403,Q8N183,P06753,P00846,Q9P0J0,Q969G3,P03915,Q10713,Q96CU9 11 +Abnormality of endocrine pancreas physiology 0.395003206994331 0.1654827709136153 0.8685640096926541 1.0 1.0 4 P53985 1 +Abnormal rib cage morphology 0.2861008559165895 0.1651944091262528 0.8687909656815571 1.0 1.0 72 O75431,Q9Y5S9,P00813,P54802,P98172,P16278,O75844,P41227,Q03164,P15586,Q14696,O95831,P17252,Q14739,P16435,P02545,Q8TAA9,Q32P28,O75718,Q96HY6,P48651,O96028,O60826 23 +Abnormality of thalamus morphology 0.2918874518025225 0.1641400379718713 0.8696209034838878 1.0 1.0 17 Q969G3,Q9UPT5,Q9Y5P6 3 +Localized osteoporosis 0.6340508806262133 0.1638685871321887 0.8698345966089369 1.0 1.0 2 P57740 1 +Rib fusion 0.3528980510960193 0.1618339666504015 0.871436604086562 1.0 1.0 7 O96028,O95202,Q9H3P2 3 +Ileus 0.4651778014325559 0.1613862620224342 0.8717891861598217 1.0 1.0 3 P50336 1 +Vocal cord paralysis 0.2894557964502361 0.1612331377214876 0.8719097824174828 1.0 1.0 19 Q9BTV4,Q8TB36,P50402,Q9NR77,P02545,P21912 6 +Hyperphosphatemia 0.4636215334420823 0.1585996962168119 0.8739842681501027 1.0 1.0 3 P29992,Q15813 2 +Adrenocortical carcinoma 0.4636215334420702 0.1585996962167905 0.8739842681501195 1.0 1.0 3 P25054,P04637 2 +Abnormality of the extraocular muscles 0.4632952691680101 0.1580191996102279 0.8744416696901123 1.0 1.0 3 P43243,Q9BVA1 2 +Abnormality of lower limb epiphysis morphology 0.2983690490232935 0.1573225296419146 0.8749906652601585 1.0 1.0 15 O95831 1 +Facial edema 0.3021289488835836 0.1563592285530348 0.8757498727396782 1.0 1.0 24 Q8NFH4,P28070,O43707,Q9BW27,O00170,Q14331,Q8WUM0,Q14C86,Q8N1F7,Q12769 10 +Abnormal duodenum morphology 0.3064153215882544 0.1560030029483272 0.8760306541936784 1.0 1.0 12 P98175,P49454 2 +Abnormality of the nasal skeleton 0.3530147587870918 0.155751513864969 0.8762288904171485 1.0 1.0 5 Q6NUK1,O14974 2 +Abnormality of cardiovascular system electrophysiology 0.2718584343886465 0.1553582183071405 0.8765389211304213 1.0 1.0 107 P07602,P23786,P00403,P50402,P46100,P00846,O75381,P42892,P56589,P03915,O43772 11 +Eeg with focal spikes 0.4616639477977116 0.1551359383521969 0.8767141504411855 1.0 1.0 3 P36776,O75503 2 +Hyperglycemia 0.3319665287190447 0.1550198226035292 0.8768056900351167 1.0 1.0 9 P02545,O75844 2 +Abnormal peripheral nervous system physiology 0.3270939133318886 0.1542610158678473 0.8774039341617037 1.0 1.0 50 Q9Y619,P07602,Q9NR77,Q92734,O15121,O95721,O95831,Q9UBB4,P02545,P07196,Q9Y6X9,P20700,Q9GZY8 13 +Broad columella 0.3870937629853916 0.1493913094642162 0.8812448688245329 1.0 1.0 4 Q13868 1 +Moderately reduced visual acuity 0.4580750407830245 0.1489056595360067 0.8816280753422303 1.0 1.0 3 O00429,O60313 2 +Connective tissue nevi 0.6223091976516526 0.1470808385644586 0.8830682139944319 1.0 1.0 2 Q6NUK1 1 +Cutaneous finger syndactyly 0.622309197651649 0.1470808385644538 0.8830682139944357 1.0 1.0 2 Q9Y619 1 +Vitreous floaters 0.4567555956007859 0.1466541952594758 0.8834049744687598 1.0 1.0 3 P04439 1 +Dysplastic corpus callosum 0.3036864818968023 0.1465424623191428 0.8834931716209564 1.0 1.0 12 Q15233,O14974 2 +Lower limb spasticity 0.2621645955186302 0.1458861582980024 0.8840112587578057 1.0 1.0 78 Q9H6K4,P10809,P07602,Q6DKK2,P35637,P46100,O95831,P00846 8 +Choreoathetosis 0.3189463375647566 0.1447489276711625 0.8849091072271345 1.0 1.0 34 Q9H6K4,P10809,O14936,P00846,Q9P0J0 5 +Cavernous hemangioma 0.3844647519582303 0.1442416230101607 0.8853096741804869 1.0 1.0 4 P21912,P36507,Q02750 3 +Abnormal basal ganglia mri signal intensity 0.3123030537962359 0.1434019901047334 0.885972711343574 1.0 1.0 30 Q9BPX6,Q8N183,P00846,Q8NI60,P03915,Q96CU9 6 +Hyperlipidemia 0.3122807424075389 0.1432941798298849 0.8860578522220255 1.0 1.0 30 O75431,P28070,Q9BTV4,P50402,O75844,P22830,P23786,Q92734,P02545 9 +Respiratory paralysis 0.4541657021010187 0.1422960079445543 0.8868461996400703 1.0 1.0 3 P50336 1 +Porphyrinuria 0.4541657021010187 0.1422960079445543 0.8868461996400703 1.0 1.0 3 P50336 1 +Elevated urinary dicarboxylic acid level 0.4541657021010187 0.1422960079445543 0.8868461996400703 1.0 1.0 3 P50336 1 +Elevated urinary delta aminolevulinic acid 0.4541657021010187 0.1422960079445543 0.8868461996400703 1.0 1.0 3 P50336 1 +Retinal hemorrhage 0.3541676286563063 0.1422268131152405 0.8869008532698803 1.0 1.0 6 P36543 1 +Color vision defect 0.2866101758237301 0.1419752620668097 0.8870995457368258 1.0 1.0 17 Q9H6K4,Q9H061,Q9Y4W6,Q6P4Q7 4 +Bilateral cryptorchidism 0.3194487307459197 0.1409369791789025 0.8879197285387619 1.0 1.0 10 Q15233,O43924,P37268,P36543 4 +Scaphocephaly 0.3825587939632329 0.1405706356424772 0.8882091472137121 1.0 1.0 4 P40855 1 +Medulloblastoma 0.3523840627041105 0.1379425830479106 0.8902857956742791 1.0 1.0 6 P25054,P35222,Q12824,O60934,P04637 5 +Abnormal femoral neck morphology 0.3209113456403863 0.1364817322061335 0.8914404650016403 1.0 1.0 37 O75431,O75844,P46100,O95831,P02545,Q96AY3,Q96HY6 7 +Abnormal qt interval 0.3260493221513891 0.1359632691068585 0.8918503182678843 1.0 1.0 9 Q16836,Q9Y5P6 2 +Macular thickening 0.3436785364260074 0.1359117169658149 0.8918910726303846 1.0 1.0 7 P04439,P25054,Q8WWY3,P35222,P36405,P50213 6 +Long hallux 0.3792428198433468 0.1343091751645675 0.8931580982482941 1.0 1.0 4 O60762,P10644,P52788 3 +Lambdoidal craniosynostosis 0.4490932700916138 0.1339950807588738 0.8934064643421049 1.0 1.0 3 P61978 1 +Acquired abnormal hair pattern 0.3424648888366719 0.1326148471097296 0.8944979898414669 1.0 1.0 7 O75844 1 +Telangiectasia 0.3150431716302846 0.1324287440890896 0.8946451803946622 1.0 1.0 33 P00846,Q8IZA0,P03915 3 +Neoplasm of the skeletal system 0.3210588354770149 0.1321932515679076 0.8948314387469543 1.0 1.0 38 Q13126,P48735,Q92804 3 +Malignant neoplasm of the central nervous system 0.28856238248339 0.1314289402834375 0.8954359961877434 1.0 1.0 21 P48735 1 +Increased susceptibility to fractures 0.3226815547267695 0.1305534704976667 0.8961285527467113 1.0 1.0 51 P48735,P22626,P06753,Q14696,P16435,Q13126,Q32P28,Q96AY3,P17252,Q14108,O75718,Q14739,P09651,O75874 14 +Dysphagia 0.284337032912769 0.1289454040968748 0.8974008492618193 1.0 1.0 126 P06753,Q96CV9,Q01105,Q14108,Q15067,Q15233,Q9NR77,Q03164,P15586,P00846,Q8IZA0,Q86U42,O75874,Q8N3U4,P48735,P03915,Q9HD42,P07602,Q8N183,Q92734,O15344,P35637,O15118,P17480,P20700 25 +Abnormal circulating phenylalanine concentration 0.4456769983686768 0.1285795868414764 0.8976903195494281 1.0 1.0 3 P61457,P09417 2 +Abnormality of peripheral nerves 0.3239040113061999 0.1280752800510695 0.8980893985787897 1.0 1.0 46 Q9Y619,P07602,Q9NR77,Q92734,O15121,O95721,O95831,Q9UBB4,P02545,P07196,Q9Y6X9,Q9GZY8 12 +Reduced forced expiratory volume in one second 0.6076320939334512 0.1279127563356364 0.8982180158808164 1.0 1.0 2 O95453 1 +Sclerosis of skull base 0.4451755761343777 0.1277965865651587 0.8983099514409292 1.0 1.0 3 P48651 1 +Increased megakaryocyte count 0.4427406199021066 0.1240373779578908 0.9012856802389456 1.0 1.0 3 O75533,P04637 2 +Progressive visual field defects 0.6030658838877891 0.1223562318298075 0.9026168999326458 1.0 1.0 2 P35222 1 +Abnormal circulating carboxylic acid concentration 0.2539950168357459 0.1203170400134806 0.9042320061890164 1.0 1.0 89 P48735,P55263,O14936,P23786,P41440,O96000,P37268,P00846,P22695,O14874,Q16134,Q9P0J0,P40855,Q9NSD9,P03915 15 +Glossoptosis 0.3373723709539209 0.1190797809908125 0.905212149185766 1.0 1.0 7 P98175 1 +Abnormality of periauricular region 0.2825240061940757 0.1182254506261255 0.9058890246872472 1.0 1.0 20 O96028,P61978,Q07954,Q8N3U4,O60826,Q13428 6 +Preaxial hand polydactyly 0.3438347846667547 0.1181576782176359 0.9059427228711648 1.0 1.0 6 O96028,Q9H3P2 2 +Positional foot deformity 0.2545610384380216 0.1173805123424936 0.9065585262065016 1.0 1.0 90 Q9Y5S9,Q9Y619,Q8TB36,P06753,P21964,P07196,Q96A33,Q969X5,Q9H267,Q9NR77,Q9NVI7,P61978,Q8TD16,Q8NI60,Q15392,Q9Y487,P10412,P16435,Q8TAA9,P02545,Q96AY3,Q9HD42,Q9BX10,P36543,O96028,P46100,P98175,Q9NWM8 28 +Prominent nasal bridge 0.3219659562492027 0.1173505330303999 0.9065822820575782 1.0 1.0 47 Q15233,O14936,P21964,Q96EK5,Q8WVM7,P42892,P49454,P20700,Q10713 9 +High narrow palate 0.3102934041813022 0.1171302893077918 0.906756807538168 1.0 1.0 32 Q15233,P23786,P06753,P61978,P16435,O60826,P48651 7 +Meningocele 0.3118725570639526 0.116961835545384 0.906890296669447 1.0 1.0 10 P21964,Q10713,Q9Y5P6 3 +Abnormal protein glycosylation 0.2755606324094741 0.1151828168728294 0.9083002181700788 1.0 1.0 18 Q15904,Q2TAA5,Q9Y487,P36543,Q8N511,Q9Y2V7 6 +Progressive 0.2650056102087491 0.1150621933207671 0.908395826180458 1.0 1.0 103 P54802,Q15043,Q13126,O75477,Q9Y6M9,Q03252,P15586,O15121,O95831,Q86U42,P28288,P10809,P02545,Q8N1F7,Q12769,Q5U5X0,P55263,Q8N183,Q9Y4W6,Q9NR28,P20700 21 +Multiple joint contractures 0.2811829463108304 0.1126626780985339 0.9102979913678124 1.0 1.0 20 P41440,O75844,Q15043,P02545,Q9Y5P6 5 +Streak ovary 0.3406270411495737 0.1110580964359014 0.9115702773196696 1.0 1.0 6 P82650,O14974,O75616,P51809,P57740 5 +Thyroid carcinoma 0.28582386039593 0.1105468210854238 0.9119757195246389 1.0 1.0 15 Q8TAQ2,Q92785,P21912,Q969G3,P04637 5 +Branchial anomaly 0.3173975284549951 0.1094503279504394 0.9128453175470445 1.0 1.0 9 P61978 1 +Lipodystrophy 0.3085027887047566 0.108704095623181 0.9134371932713716 1.0 1.0 32 O75431,P28070,Q9BTV4,P50402,O75844,P02545,Q03252 7 +Malar prominence 0.4319738988580709 0.1082695812727179 0.9137818513724252 1.0 1.0 3 Q9Y4W2,Q96MF7 2 +Abnormal adipose tissue morphology 0.3133203784909055 0.1080013692559279 0.9139946060554468 1.0 1.0 57 O75431,P28070,Q9BTV4,Q2TAA5,O75844,Q9Y487,P41227,P50402,P36543,P02545,P17252,P53680,P03915,Q9BUK6,Q03252 15 +Severe varicella zoster infection 0.4306688417618191 0.106452592178338 0.915223267564922 1.0 1.0 3 Q9H0U3,P17812 2 +Reduced antigen specific t cell proliferation 0.4306688417618184 0.1064525921783369 0.9152232675649228 1.0 1.0 3 Q96MG7,P17812 2 +Abnormal t cell proliferation 0.4306688417618184 0.1064525921783369 0.9152232675649228 1.0 1.0 3 Q96MG7,P17812 2 +Hypopigmented skin patches 0.2851278287117773 0.1048746293266971 0.9164752907941144 1.0 1.0 22 Q8IZA0 1 +Shoulder girdle muscle atrophy 0.3610518169355202 0.1028007228391376 0.9181211315631004 1.0 1.0 4 P06753 1 +Neuroendocrine neoplasm 0.2896601052906629 0.1010078258708268 0.9195442478053356 1.0 1.0 12 P46100 1 +Polygenic inheritance 0.3258243552073185 0.0994663416169481 0.9207680108401644 1.0 1.0 5 P35658,P04637,P11274,O60934 4 +Temporal optic disc pallor 0.5799086757990742 0.0970735015510169 0.9226680241568116 1.0 1.0 2 O60313 1 +Morning glory anomaly 0.5799086757990742 0.0970735015510169 0.9226680241568116 1.0 1.0 2 O60313 1 +Broad philtrum 0.2964475567334825 0.0955176722119644 0.9239036540411624 1.0 1.0 11 Q92785,Q969G3,Q8TAQ2 3 +Abnormal echocardiogram 0.4188632983291087 0.0909316697000936 0.9275468856455455 1.0 1.0 3 P49748 1 +Paralysis 0.3169612120965437 0.0897434848719302 0.9284910594056928 1.0 1.0 48 Q15233,Q9NR77,P50402,P50995,Q96CV9,P35637,P02545,P20700,Q92804,Q15165 10 +Hammertoe 0.2730722953487045 0.0893644760945187 0.928792254451594 1.0 1.0 17 Q9NR77 1 +Skin appendage neoplasm 0.3521540469973944 0.0891357457587238 0.9289740294392748 1.0 1.0 4 P25054,P43246,P35222 3 +Spastic paraparesis 0.2685054028044127 0.0874226142628612 0.9303355946103512 1.0 1.0 18 Q6DKK2 1 +Abnormality of the epiphyses of the distal phalanx of finger 0.569145466405726 0.0869166867598756 0.9307377355997696 1.0 1.0 2 P82673 1 +Scaling skin 0.3169756711163969 0.0865588257838183 0.9310221952734028 1.0 1.0 8 O75844 1 +Stenosis of the external auditory canal 0.328572208848191 0.0859783123030964 0.9314836576488166 1.0 1.0 6 O96028,P16435 2 +Bruising susceptibility 0.3002287323495166 0.0793226593876204 0.9367759835011312 1.0 1.0 31 Q13126,P46100,Q9NWM8 3 +Unsteady gait 0.3138812741643024 0.0779045287316023 0.9379039969552484 1.0 1.0 51 Q5JRX3,O95831,Q10713,Q9NR77 4 +Abnormality of fundus pigmentation 0.3433420365535328 0.0767195584758831 0.9388466449831308 1.0 1.0 4 P25054,Q9Y619,P38435 3 +Cystoid macular edema 0.3433420365535244 0.0767195584758717 0.93884664498314 1.0 1.0 4 P04439,P36405,P50213 3 +Genital neoplasm 0.3011098181400724 0.075213070593699 0.9400451849823476 1.0 1.0 32 O75874,Q13423,P48735,P02545 4 +Abdominal obesity 0.4052889915010177 0.0750853802992784 0.9401467798177112 1.0 1.0 3 O00170 1 +Ulnar deviation of the wrist 0.4046994763059318 0.0744445780009952 0.940656639069946 1.0 1.0 3 P16435 1 +Neoplasm of the oral cavity 0.2884096856338066 0.07260584942979 0.9421197718367028 1.0 1.0 11 Q969G3 1 +Megalencephaly 0.4009787928221775 0.0704894790209355 0.9438040742460188 1.0 1.0 3 O00459,P52788 2 +Hiatus hernia 0.3085210577864892 0.070235360891994 0.9440063298862726 1.0 1.0 5 Q8NBU5,P54886,Q8WUM0,P57740 4 +Scarring alopecia of scalp 0.5485975212002437 0.0701682407312694 0.9440597522234386 1.0 1.0 2 Q15149 1 +Sparse eyebrow 0.3014844050176505 0.069311579809074 0.944741608551493 1.0 1.0 33 O75431,Q9BX10,O75844,P41227,P61978,Q96EK5,P02545,Q00577,Q8N3U4,Q08J23,Q07954 11 +Microscopic hematuria 0.336879589847851 0.0683093583576648 0.9455393746397452 1.0 1.0 4 Q03252 1 +Micronodular cirrhosis 0.3188770725111438 0.0676557531446718 0.946059672437178 1.0 1.0 6 P11717,Q9NWH9,P04637 3 +Deep philtrum 0.2726591612686871 0.0667042200720216 0.946817174665506 1.0 1.0 15 Q7LGA3,Q00577 2 +Vaginal fistula 0.3183206706963882 0.0666543048823511 0.9468569127861168 1.0 1.0 6 Q13428 1 +Urogenital fistula 0.3183206706963882 0.0666543048823511 0.9468569127861168 1.0 1.0 6 Q13428 1 +Aplasia hypoplasia of the 5th finger 0.2748014667440828 0.0664532931234665 0.947016942154352 1.0 1.0 14 Q92785,Q969G3,O14497,Q8TAQ2 4 +Headache 0.2973518934406916 0.0657697829608444 0.9475611138340778 1.0 1.0 63 Q8NFH4,P06753,P00403,P23786,Q14C86,Q969G3,P00846,Q9NSD9,Q8N1F7,P03915,Q12769 11 +Abnormality of the calf musculature 0.2663626046194532 0.0656585660519635 0.9476496606936888 1.0 1.0 17 Q8NAT1,Q9NR77 2 +Bulbous nose 0.3103249254070454 0.0655389892671064 0.9477448641039355 1.0 1.0 41 O75431,Q9UGU0,P38159,P23786,P21964,Q96EK5,P42892,Q8N3U4 8 +Urinary retention 0.3046270362320204 0.06435744136501 0.9486856166099892 1.0 1.0 5 P20700 1 +Ankle clonus 0.2731780429369621 0.0616588417748648 0.9508345170763096 1.0 1.0 14 P07602 1 +Generalized amyotrophy 0.2848159757337309 0.060774559970803 0.9515387510622828 1.0 1.0 26 P22626,P35637,P02545,P09651,Q03252 5 +Sarcoma 0.3070139721685664 0.0602789279444148 0.9519334844869862 1.0 1.0 56 P48735,Q15392,Q13126,Q92804,O75874 5 +Abnormally large globe 0.3068396595903306 0.0597558263227707 0.9523501081567152 1.0 1.0 8 O75431,O14936 2 +Paraparesis 0.2790680426056893 0.0587917805999971 0.9531179552688795 1.0 1.0 24 P35637,Q6DKK2 2 +Abnormal glial cell morphology 0.3066645575299268 0.0581442128531199 0.953633757177166 1.0 1.0 56 P48735,Q92734,P35637,O95831,P00846,Q16134,O75874,P20700,Q10713 9 +Hand tremor 0.2828083215541875 0.0576402166006329 0.95403521469335 1.0 1.0 11 Q92734,Q96KR1 2 +Decreased number of large peripheral myelinated nerve fibers 0.2994870626889804 0.0569862335273492 0.9545561613739424 1.0 1.0 5 P07196 1 +Abnormal glycosylation 0.2726647149003736 0.0561611906614855 0.9552133977076428 1.0 1.0 22 Q15904,Q2TAA5,Q9Y487,P36543,Q9BT22,P46977,Q8N511,Q9Y2V7,Q8TCJ2 9 +Lipid accumulation in hepatocytes 0.2847500614321356 0.0554183998604311 0.9558051373939264 1.0 1.0 68 O75431,Q15904,P22626,P55263,Q9NSD9,P23786,Q16836,Q16134,P02545,O43772,Q8N511,Q15067,Q03252 13 +Abnormal prostate morphology 0.3115610711952912 0.0549209401311155 0.9562014492426248 1.0 1.0 6 P25054,P04637,O60934,Q92878,P49959 5 +Hypoplastic aortic arch 0.5244618395303136 0.0545681298179341 0.9564825296332936 1.0 1.0 2 P30153 1 +Foot oligodactyly 0.5228310502282936 0.0536598437031933 0.957206176763682 1.0 1.0 2 P25054 1 +Impaired distal proprioception 0.5212002609262698 0.052768977176637 0.9579159796751692 1.0 1.0 2 Q6PI48 1 +Dysmetria 0.3066791675805471 0.0522969830920764 0.9582920571731844 1.0 1.0 55 Q9BX10,Q8IV08,Q6DKK2,P41440,Q5JRX3,Q8N183,O14773,Q96BR5,O15121,P34897,Q9Y4W6,Q9UBB4,P20700,Q9BUK6,Q10713 15 +Mediastinal lymphadenopathy 0.2953482831708793 0.0513674132966657 0.9590327509006562 1.0 1.0 5 Q01844,O15460 2 +Weakness of muscles of respiration 0.2971559633046743 0.0506875993401441 0.9595744582405628 1.0 1.0 33 P22626,P50336,Q9BTV4,P06753,P50402,O95831,Q8TD16,P02545,P36551,Q15067,Q9Y6X9,P09651 12 +Abnormal electroretinogram 0.2909191726560438 0.0485816526867991 0.9612526917329196 1.0 1.0 30 P00846 1 +Glycosuria 0.2869330649081754 0.0477233423424436 0.9619367307961776 1.0 1.0 10 Q16134,P02545 2 +Vitreous hemorrhage 0.2916129455947576 0.0465353941041771 0.962883524216756 1.0 1.0 5 P35222,O75533,Q99496 3 +Esophageal carcinoma 0.3729200652528499 0.0454129530971851 0.963778156561488 1.0 1.0 3 P25054,Q8N9N2 2 +Lack of skin elasticity 0.2653143479345373 0.0446726832349075 0.9643682075741532 1.0 1.0 15 P17252,O75844 2 +Redundant skin 0.2717486721375147 0.0422123235647293 0.9663294385337212 1.0 1.0 23 P36543,Q9Y487,P41227,O96000,P48651 5 +Trophic changes related to pain 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Penetrating foot ulcers 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Emg slow motor conduction 0.4977168949771491 0.0417550860807124 0.9666939398772976 1.0 1.0 2 O15269 1 +Agammaglobulinemia 0.3667210440456758 0.0409355828540015 0.9673472501961368 1.0 1.0 3 O60220,Q8IWT6 2 +Aplasia hypoplasia of the sacrum 0.3618270799347465 0.0376522123690455 0.9699649779588304 1.0 1.0 3 Q8TAA9,P39019 2 +Noncompaction cardiomyopathy 0.3601091154788903 0.0365507112635041 0.9708432439575304 1.0 1.0 3 Q15233 1 +Duplication involving bones of the feet 0.2610377937241269 0.0326604223129125 0.973945385459609 1.0 1.0 15 Q7Z4L5,P21964,O96028,O43924,Q14739,Q10713 6 +Pilomatrixoma 0.3520391517128859 0.0317192620387682 0.9746959337293726 1.0 1.0 3 P25054,P35222 2 +Abnormal larynx morphology 0.2769240089028544 0.0310577273119429 0.9752235021106 1.0 1.0 26 P07602,P36543,P21964,P16435,P02545,Q96HY6 6 +Accelerated skeletal maturation 0.2799209275937634 0.0310255367993933 0.9752491740520643 1.0 1.0 10 O00170,Q03164 2 +Congenital craniofacial dysostosis 0.463470319634689 0.0308894075503408 0.9753577374439252 1.0 1.0 2 Q6NUK1 1 +Mild postnatal growth retardation 0.463470319634685 0.0308894075503399 0.975357737443926 1.0 1.0 2 Q9Y3E5 1 +Muscle fiber tubular inclusions 0.298955613577031 0.0301166251400025 0.9759740418006972 1.0 1.0 4 O75340,Q9Y5P6,Q13586 3 +Abnormality of the lymph nodes 0.2996919178160617 0.030090567719297 0.9759948231959126 1.0 1.0 38 P28070,P00813 2 +Restlessness 0.3008253259548108 0.0300038090875205 0.9760640153271628 1.0 1.0 39 P50995,Q96CV9,P35637,Q92804,P42892,Q15165,P09651 7 +Abnormal fundus autofluorescence imaging 0.4585779517286196 0.0297503098914876 0.9762661881675236 1.0 1.0 2 Q8WWY3 1 +Abnormal 3rd finger morphology 0.4562948467057903 0.0292491301833077 0.9766658977565096 1.0 1.0 2 Q9Y3E5 1 +Hypoplasia of the ear cartilage 0.3443276757652007 0.0276068858496926 0.9779756896460648 1.0 1.0 3 Q8WUM0 1 +Striae distensae 0.2860009950672685 0.0275027255229646 0.9780587660179972 1.0 1.0 9 O00170,P17252 2 +Cerebellar cortical atrophy 0.3440847336667881 0.0274849898800388 0.978072911666219 1.0 1.0 3 Q9H173 1 +Hypopigmentation of the fundus 0.3432300163132085 0.0270597603632605 0.9784120695765935 1.0 1.0 3 Q9Y619,P38435 2 +Medial flaring of the eyebrow 0.4386823222439404 0.0259731870538034 0.9792787248654105 1.0 1.0 2 Q96ST3 1 +Hand polydactyly 0.2826996963820458 0.0252606974969806 0.979847022773498 1.0 1.0 29 O00459,O43924,P21964,O96028,P98172,P98175,Q14739,Q15067,O60826,Q10713 10 +Bifid ribs 0.4099804305283648 0.0224602507700074 0.982080819285055 1.0 1.0 2 Q9UM00 1 +Pace of progression 0.2955590744674326 0.0223337520084665 0.9821817253820636 1.0 1.0 155 Q5JTV8,P54802,Q15043,Q13126,O75477,Q14108,Q9P0J0,Q9Y6M9,Q03252,Q9NR77,P15586,O15121,O95831,Q86U42,Q10713,P28288,P10809,Q8IV08,P50402,P02545,Q8N1F7,O14979,Q12769,Q5U5X0,P55263,Q9BTV4,P41440,Q8N183,Q92734,O14773,Q96BR5,Q9Y4W6,Q9NR28,P20700 34 +Abnormality of corneal stroma 0.2680539519509007 0.0222086114978899 0.9822815483038874 1.0 1.0 11 P34913,Q16625,P10619 3 +Focal cortical dysplasia 0.4008480104370417 0.0217060534236115 0.982682434977761 1.0 1.0 2 Q8WUM0 1 +Abnormal conus terminalis morphology 0.2891439672805199 0.0216499003366781 0.9827272281326956 1.0 1.0 6 O96028,O95202,Q9H3P2 3 +Abnormality of chorioretinal pigmentation 0.2868604894361429 0.0215790977399952 0.9827837072367612 1.0 1.0 4 Q9Y619 1 +Abnormal circulating glutamine family amino acid concentration 0.2683764977687496 0.0213497865351629 0.9829666289634044 1.0 1.0 5 O96000 1 +Abnormal drinking behavior 0.3953033268101673 0.021315811417913 0.9829937310172928 1.0 1.0 2 Q8N5K1 1 +Abnormal meningeal morphology 0.259427763457039 0.0212057229512417 0.9830815490551204 1.0 1.0 21 Q15904,P21964,Q10713,Q8N3U4,Q9Y5P6 5 +Undetectable visual evoked potentials 0.3930202217873413 0.021168607821724 0.9831111559979684 1.0 1.0 2 Q8TC12 1 +Corticospinal tract hypoplasia 0.3907371167645025 0.0210288166298727 0.9832226684086394 1.0 1.0 2 P11177 1 +Generalized dystonia 0.385518590998039 0.0207355519849666 0.9834566087279748 1.0 1.0 2 O60220 1 +Abnormal length of corpus callosum 0.3848662752772227 0.0207013380790365 0.9834839016168608 1.0 1.0 2 P11177 1 +Pontocerebellar atrophy 0.3796477495107575 0.0204458797784283 0.9836876847177456 1.0 1.0 2 O60762 1 +Deposits immunoreactive to beta amyloid protein 0.3789954337899459 0.0204161369895514 0.9837114110772672 1.0 1.0 2 O96008 1 +Central primitive neuroectodermal tumor 0.3519243313763825 0.0195293396466302 0.9844188318497892 1.0 1.0 2 P04637 1 +Germinoma 0.3519243313763815 0.0195293396466302 0.9844188318497892 1.0 1.0 2 P35222 1 +Aplasia hypoplasia of the gallbladder 0.3506196999347637 0.0195006110779511 0.98444174956685 1.0 1.0 2 P18583 1 +Pseudohypoaldosteronism 0.3365949119373755 0.0192506652035495 0.9846411400899078 1.0 1.0 2 Q9H4A3 1 +Hyperchloremic acidosis 0.3365949119373755 0.0192506652035495 0.9846411400899078 1.0 1.0 2 Q9H4A3 1 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.3118069145466382 0.0190015077899579 0.9848399025852088 1.0 1.0 2 P12235 1 +Vertical nystagmus 0.3075668623613794 0.0189756783230044 0.984860507802992 1.0 1.0 2 P49959 1 +Severe demyelination of the white matter 0.2824527071102367 0.0188822942343452 0.9849350041780668 1.0 1.0 2 Q9H9P8 1 +Lop ear 0.2808219178082178 0.0188787749981862 0.984937811621828 1.0 1.0 2 P78318 1 +White hair 0.2641201436500242 0.0175962941546435 0.9859609130564736 1.0 1.0 5 Q9NX24,P06748,Q9Y4I1,O95453 4 +Abnormal dental root morphology 0.2641201436500224 0.0175962941546418 0.9859609130564748 1.0 1.0 5 Q9NX24,P06748,Q13045,O95453 4 +Cutis laxa 0.275472292111027 0.0166988794140592 0.986676841135214 1.0 1.0 27 Q15904,Q9Y487,P36543,O96000,P41227,P48651 6 +Impaired mastication 0.2894197399684945 0.0162769744613057 0.9870134268268348 1.0 1.0 7 P06753 1 +Scrotal hypoplasia 0.2501825144646736 0.0152267889359316 0.9878512496575204 1.0 1.0 17 Q8TCJ2,P46100,Q13428 3 +Skeletal muscle hypertrophy 0.3013590119833904 0.0139203885183531 0.9888934956199044 1.0 1.0 44 Q9NR77,P61978,P46100,Q8NAT1,Q10713 5 +Pericarditis 0.258316973395542 0.0128768883290562 0.9897260135407464 1.0 1.0 5 O15460 1 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.2988580750407851 0.0116702453443753 0.9906887027775289 1.0 1.0 3 O75340,Q9Y5P6 2 +Response to drugs acting on neuromuscular transmission 0.2988580750407851 0.0116702453443753 0.9906887027775289 1.0 1.0 3 O75340,Q9Y5P6 2 +Single fiber emg abnormality 0.2988580750407851 0.0116702453443753 0.9906887027775289 1.0 1.0 3 O75340,Q9Y5P6 2 +Abnormal hypothalamus morphology 0.2901203111668656 0.0098962013037697 0.9921041026498568 1.0 1.0 3 O43924 1 +Abnormal salivary gland morphology 0.2541630901331152 0.0097703991885356 0.9922044733625226 1.0 1.0 5 Q13428 1 +Abnormal metaphyseal trabeculation 0.2640339425587541 0.0094748762172918 0.9924402556613804 1.0 1.0 4 Q9NX24,P06748,O95453 3 +Oral leukoplakia 0.2640339425587541 0.0094748762172918 0.9924402556613804 1.0 1.0 4 Q9NX24,P06748,O95453 3 +Neoplasm of the tongue 0.2847803332116927 0.0087265523990249 0.993037306943225 1.0 1.0 7 O43924,Q969G3 2 +Food allergy 0.2584856396866878 0.0072254228685407 0.9942349968099626 1.0 1.0 4 Q9Y5S9,Q01082,O95394 3 +Specific learning disability 0.2847601759189428 0.0065619647569211 0.9947643472059422 1.0 1.0 65 Q9H6K4,P48651,P22626,Q9BPX6,P00403,P35637,Q96EK5,Q8NAT1,P09651,Q9NSD9,P03915,Q10713 12 +Anterior uveitis 0.2662316476345876 0.0065054228942822 0.9948094601222484 1.0 1.0 3 P14174,P01889 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a40879595879f9added86aa1783d29b306802ce7 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal coccyx morphology", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crossed fused renal ectopia", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal bleeding", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postprandial hyperglycemia", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent coccyx", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowed slurred speech", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue neoplasm", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ANAPC1", "ANAPC2", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATR", "ATRX", "ATXN10", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDK", "BCR", "BCS1L", "BICD2", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRD4", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD3EAP", "CDC42", "CDC73", "CDH2", "CDK13", "CDK4", "CELF2", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHM", "CHMP1A", "CHORDC1", "CISD2", "CIZ1", "CLASP1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COG4", "COG6", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ5", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DICER1", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S3", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPKOW", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2E2", "GTF2I", "GTPBP2", "GTPBP3", "GUF1", "GUSB", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ITCH", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KMT2A", "L2HGDH", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPP", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LYRM7", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MESD", "MFF", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MMADHC", "MOGS", "MORC2", "MPG", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCDN", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEMF", "NF1", "NFKB2", "NFU1", "NHLRC2", "NHP2", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NR3C1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "OPTN", "OSGEP", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKB", "PICALM", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RNF213", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RRP7A", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC5A6", "SLMAP", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STK4", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TALDO1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMM8A", "TIMMDC1", "TJP2", "TKT", "TLK2", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRRAP", "TSFM", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUFM", "UBA1", "UBA5", "UBE4A", "UBTF", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13D", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR11", "WDR36", "WNK1", "XIAP", "XPC", "XPNPEP3", "YARS", "YARS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["ABCD3", "ABHD12", "ACADVL", "ACAT2", "ACBD5", "ACOX1", "ACTN4", "ADA", "ADAR", "ADK", "AFG3L2", "AIFM1", "AIP", "ALDH18A1", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANXA11", "AP2S1", "APC", "ARID1A", "ARL3", "ASCC1", "ATAD1", "ATAD3A", "ATP1A1", "ATP2A2", "ATP6", "ATP6AP1", "ATP6V0A2", "ATP6V1E1", "ATP7B", "ATRX", "ATXN10", "BCAP31", "BCKDK", "BCR", "BCS1L", "BICD2", "C19orf70", "CASK", "CCDC22", "CCDC47", "CCT5", "CDK13", "CDK4", "CENPF", "CHMP1A", "CISD2", "CIZ1", "CLN5", "CNNM4", "COA3", "COA7", "COG6", "COMT", "COQ8A", "COX2", "CPOX", "CPT2", "CRTAP", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CYFIP2", "DAG1", "DARS2", "DDRGK1", "DEGS1", "DHCR24", "DHPS", "DIABLO", "DLG1", "DNAJC3", "DNM1L", "DPF2", "DPM1", "ECE1", "EFNB1", "EMD", "EPHX2", "ERAL1", "ERGIC1", "ERLIN1", "ERLIN2", "ETFDH", "EWSR1", "EXOC7", "EXOSC2", "FAR1", "FARSB", "FDFT1", "FECH", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLII", "FOXRED1", "FRG1", "FUS", "GAPVD1", "GDAP1", "GGCX", "GLB1", "GLRX5", "GMPPB", "GNA11", "GNS", "GPKOW", "GTPBP2", "HADH", "HCCS", "HEXA", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPRT1", "HS2ST1", "HSPB1", "HSPD1", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGBP1", "IGF2R", "KDSR", "KIAA0319L", "KIFBP", "KMT2A", "L2HGDH", "LAS1L", "LBR", "LETM1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPP", "LRP1", "LRRC8A", "LYRM7", "MAGT1", "MAP2K1", "MAP2K2", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MESD", "MFF", "MIA3", "MICU1", "MID1", "MIF", "MMADHC", "MORC2", "MRE11", "MRPS16", "MRPS22", "MRPS35", "MSH2", "MSH3", "MSTO1", "MTAP", "MTPAP", "MTX2", "MYO5A", "NAA10", "NAGLU", "NBN", "ND5", "NDUFA11", "NDUFA13", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB9", "NEFL", "NEK9", "NELFA", "NHP2", "NNT", "NONO", "NPC1", "NPM1", "NSD2", "NSMCE2", "NSMCE3", "NSUN2", "NTHL1", "NUMA1", "NUP107", "NUP133", "NUP160", "NUP214", "NUP37", "NUP85", "NUP88", "NUP93", "OCLN", "OPA1", "OPA3", "OPTN", "P3H1", "P4HA2", "PABPN1", "PARN", "PCBD1", "PDCD6", "PDE6D", "PDHB", "PEX14", "PEX19", "PEX3", "PGM3", "PIK3R2", "PITRM1", "PLD3", "PLEC", "PLOD1", "PMPCA", "PMVK", "POLR3A", "POMGNT2", "PON2", "POR", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPT1", "PRCC", "PREPL", "PRKAR1A", "PRKCA", "PRKCSH", "PRKRA", "PRPF31", "PSAP", "PSMB4", "PTCD3", "PTDSS1", "PTPRF", "PTRH2", "PURA", "PXMP2", "QDPR", "RAB3GAP2", "RAD50", "RBM10", "RBM8A", "RBMX", "RDH11", "RFC2", "RNF2", "RPL18", "RPS19", "RRAS2", "SCARB2", "SDHB", "SEC63", "SET", "SF3B1", "SF3B4", "SGPL1", "SHMT2", "SIL1", "SIN3A", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A4", "SLC39A14", "SLTM", "SMARCB1", "SMARCC2", "SMARCE1", "SMC3", "SMPD4", "SMS", "SNAP29", "SOAT1", "SON", "SPTBN1", "SPTLC1", "SPTLC2", "STAG1", "STAG2", "STIM1", "STT3A", "STT3B", "SYNE2", "TAF15", "TAP2", "TBCE", "TCF20", "TCOF1", "TERF2IP", "TFG", "TIA1", "TIMM22", "TIMM8A", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TOMM40", "TOR1AIP1", "TP53", "TPM3", "TPP1", "TTC19", "TTC21B", "TUBB2B", "UBTF", "UQCRC2", "UQCRQ", "UROD", "VAMP7", "VANGL1", "VIM", "VPS33B", "WNK1", "YIPF5", "YWHAE", "ZFR", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 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0000000000000000000000000000000000000000..8cd3d5e6e6c7f12f0ec2546a78f72275eaccafdb --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Calcium signaling pathway 3 19 2.100011235319783 0.0357278527977604 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.1040948969523729 0.2695684389372801 0.1290920553826253 0.0715305134437747 0.3885034342102743 +Riboflavin metabolism 0 5 1.9829156982658789 0.0473768468556112 1.2597087378640777 5.470873786407767 0.8651682051380694 0.3242718261444057 1.1073575266667028 1.2430881579904736 0.9666566709677474 0.2578857718572043 0.0890077655422493 0.0516364610584135 0.1008375048293403 0.2356930071839008 0.4217257773445009 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2bea8487c11a4f02da9d956e8f47d46d6e4e2d36 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 16.324022346368714 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9b35005c5fa1acaa387f75eced056f4224360599 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..059988b106f2ea63a82a56c9bde940dd8835066c --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Calcium signaling pathway 0.597989014848092 2.100011235319783 0.0357278527977604 0.9985149796111912 0.9906124726906224 19 P21796,P45880,P17252 3 +Abc transporters 0.7680597632506372 1.7839450884098604 0.0744325883544183 0.9999990293964722 0.9906124726906224 6 O15439,P08183 2 +Dilated cardiomyopathy 0.6660854276230787 1.7300966842166223 0.0836130025623604 0.9999998370229732 0.9906124726906224 9 P06753,P02545,P17252,P50402 4 +Renin angiotensin system 0.827039849950109 1.7195057699787268 0.0855223179215758 0.9999998878015496 0.9906124726906224 4 Q9UIQ6,P52888 2 +N glycan biosynthesis 0.5773328978933877 1.6620893736628406 0.0964948558977147 0.9999999870704714 0.9906124726906224 14 Q16706,P04843,Q2TAA5,Q9BT22,P46977,Q8TCJ2 6 +Hypertrophic cardiomyopathy hcm 0.6663398692810469 1.6491574896612895 0.09911537438848 0.9999999923125484 0.9906124726906224 8 Q14118,P06753,P50402,P67936,P02545,P16615,P54619 7 +Alpha linolenic acid metabolism 0.8954364532040006 1.5646525555087736 0.1176643987084704 0.9999999998144544 0.9906124726906224 3 Q15067 1 +Nicotinate and nicotinamide metabolism 0.7163463829378465 1.5639628940234434 0.1178262827398799 0.9999999998204496 0.9906124726906224 6 P43490 1 +Aldosterone regulated sodium reabsorption 0.5877451828602307 1.5075196421013886 0.1316775129846246 0.999999999989434 0.9906124726906224 11 Q9Y3B8,P17252 2 +Snare interactions in vesicular transport 0.5278091818112216 1.4344738233599386 0.1514370938982912 0.9999999999998284 0.9906124726906224 15 P56962,O95249,Q86Y82,Q9P2W9 4 +Retinol metabolism 0.6806681195412324 1.404022311456182 0.1603122057588404 0.999999999999974 0.9906124726906224 5 O94788,Q6NUM9 2 +Peroxisome 0.498631963829026 1.353571782811599 0.175873034294518 0.9999999999999992 0.9906124726906224 35 P34913,Q9UKU0,P48735,Q9BY49,Q15126,Q9NR77,O15254,O14975,P33121,Q13011,P40855,O75381,O75874,Q15067,P56589 15 +Sphingolipid metabolism 0.5117911825807265 1.182630664196237 0.236955554188277 1.0 0.9906124726906224 12 O15121 1 +Type i diabetes mellitus 0.5948264474521099 1.0343974958904305 0.3009503745869635 1.0 0.9906124726906224 5 P10809 1 +Thyroid cancer 0.5083017067045388 1.0061274720102789 0.3143542551343659 1.0 0.9906124726906224 10 Q92734,Q16204,P06753 3 +Ppar signaling pathway 0.4454665006223072 0.989133972157312 0.322597598178183 1.0 0.9906124726906224 16 Q9UKU0,P23786,O15254,O14975,Q15067 5 +Primary immunodeficiency 0.9455316373124548 0.987281526225682 0.3235046445145015 1.0 0.9906124726906224 2 P00813 1 +Vibrio cholerae infection 0.4147437056078842 0.866093386408003 0.3864389517272184 1.0 0.9906124726906224 21 Q15904,Q9Y487,P36543,Q93050,P17252,P05771 6 +Long term depression 0.4369494496764932 0.8409138106218702 0.400396220882508 1.0 0.9906124726906224 14 P17252 1 +Ecm receptor interaction 0.6018276762402068 0.8250221130976089 0.4093590364714099 1.0 0.9906124726906224 4 Q14118,P05556,Q08722 3 +Spliceosome 0.3104389217688903 0.7794955488069006 0.4356878586291912 1.0 0.9906124726906224 94 Q9Y5S9,O75940,P84103,P62312,Q08170,Q13242,P61978,P08621,Q9NW64,Q07955,O75934,P51991,Q9P013,P09012,Q86V81,Q13595,O75494,P49756,Q96I25,Q16629,P62995,P07910,P38159,P09651 24 +Proteasome 0.4155227682491468 0.7465806509767742 0.4553167316230893 1.0 0.9906124726906224 36 P49721,P28070,P28072,P20618 4 +Fatty acid metabolism 0.4085592149980417 0.7267816509493521 0.4673597252820198 1.0 0.9906124726906224 30 P42126,Q9UKU0,P23786,P35610,O15254,Q16836,Q9BWD1,P30837,P33121,Q15067 10 +Porphyrin and chlorophyll metabolism 0.4080368559132893 0.7143786075106081 0.474993096504531 1.0 0.9906124726906224 15 P22830,P30519,P50336,P53701 4 +Terpenoid backbone biosynthesis 0.4945571516675178 0.7034953125904438 0.4817471269070421 1.0 0.9906124726906224 7 Q9BWD1,Q15126 2 +Fc epsilon ri signaling pathway 0.4206343074226356 0.6807502098801147 0.4960295598409754 1.0 0.9906124726906224 12 P17252 1 +Phosphatidylinositol signaling system 0.4405805736630134 0.659657914503955 0.509473379829072 1.0 0.9906124726906224 10 P17252,Q10713 2 +Epithelial cell signaling in helicobacter pylori infection 0.3808370001606036 0.6443056721101742 0.5193772382393214 1.0 0.9906124726906224 21 Q15904,P36543,Q9Y487,Q9Y5K8,Q93050,Q9BX67 6 +Amyotrophic lateral sclerosis als 0.4357750855197793 0.635848039147134 0.5248754727369918 1.0 0.9906124726906224 10 P20339,P07197,Q9UER7,P07196,P04637 5 +Biosynthesis of unsaturated fatty acids 0.4464176052950286 0.6335290163405192 0.5263882385548408 1.0 0.9906124726906224 9 Q15067,Q9BY49 2 +Gap junction 0.370371857383424 0.6252755616045687 0.5317902165468444 1.0 0.9906124726906224 18 P17252 1 +Vegf signaling pathway 0.4016627014064376 0.6084046020934875 0.5429191599527137 1.0 0.9906124726906224 13 P17252 1 +Glycosaminoglycan degradation 0.4846066570693588 0.5739728900094055 0.565986146708362 1.0 0.9906124726906224 6 P54802,P15586,P16278 3 +Glioma 0.38276053664207 0.5696876209946536 0.5688895875840387 1.0 0.9906124726906224 15 P05771,P11802,P17252 3 +Leukocyte transendothelial migration 0.372537794653958 0.5506201855991677 0.5818940684639 1.0 0.9906124726906224 24 O00459,O43707,Q13464,P17252,Q9BX67,P05771,Q16625,O60716 8 +Gnrh signaling pathway 0.3881527350895543 0.5369535215830824 0.5912997194677805 1.0 0.9906124726906224 13 P17252 1 +Long term potentiation 0.371208063258597 0.5057796081075553 0.6130113753377169 1.0 0.9906124726906224 15 P05771,P17252 2 +Melanogenesis 0.3757924541440683 0.4997751407913131 0.617233416613042 1.0 0.9906124726906224 14 P17252 1 +Butanoate metabolism 0.3495715026861656 0.4810229384149142 0.6305001959422549 1.0 0.9906124726906224 19 P30837,P35610,Q16836,Q9BWD1 4 +Glycosaminoglycan biosynthesis heparan sulfate 0.7716894977168812 0.4530763740839578 0.6504937471798693 1.0 0.9906124726906224 2 Q7LGA3 1 +Tryptophan metabolism 0.3607415989203589 0.4494131656462513 0.6531336356408586 1.0 0.9906124726906224 15 P30837,P35610,Q16836,Q9BWD1 4 +O glycan biosynthesis 0.4808356373406524 0.3928534376998789 0.694427733569766 1.0 0.9906124726906224 4 Q10472 1 +Lysine degradation 0.3464330194925156 0.3912783268721426 0.6955915171081914 1.0 0.9906124726906224 24 P35610,Q16836,P30837,Q9BWD1,Q9NRN7,P51648 6 +Apoptosis 0.3413548885317291 0.3770897759917799 0.7061068889129152 1.0 0.9906124726906224 16 O95831 1 +Erbb signaling pathway 0.3310341222509123 0.3536560714782416 0.7235966474719508 1.0 0.9906124726906224 17 P05771,P17252 2 +Mismatch repair 0.3304380377177158 0.3210899641890212 0.7481422153949686 1.0 0.9906124726906224 16 Q9UQ84,P41440 2 +P53 signaling pathway 0.3656875799609074 0.3133239672821302 0.754034542952899 1.0 0.9906124726906224 10 P11802,P31350,Q9Y3B8 3 +Non small cell lung cancer 0.3368878339301784 0.3059769798909295 0.7596221731237898 1.0 0.9906124726906224 14 P05771,P17252 2 +Vascular smooth muscle contraction 0.3135071465475809 0.263769544857887 0.7919575033824164 1.0 0.9906124726906224 17 P05771,P17252 2 +Natural killer cell mediated cytotoxicity 0.3036794926802174 0.2428540993031032 0.8081184246066739 1.0 0.9906124726906224 18 P04439,P05771,P17252 3 +Tight junction 0.3419434136591269 0.2393912580574183 0.8108022080325534 1.0 0.9906124726906224 41 Q96A65,Q14247,O43707,O14936,P35221,P35222,P30154,P11802,P17252,Q9BX67,P05771,P62070,P20337,Q16625,Q13813,O60645 16 +Parkinsons disease 0.332186286603798 0.2033412080637399 0.8388683488765536 1.0 0.9906124726906224 53 P00403,O43676,P00846,P22695,P45880,P21796,P03915 7 +Glycine serine and threonine metabolism 0.3594709735851031 0.1812391688021217 0.8561798513981473 1.0 0.9906124726906224 7 O75600 1 +Glycerophospholipid metabolism 0.3056380010748936 0.172510833041216 0.8630359454991625 1.0 0.9906124726906224 14 Q96N66,Q8NCC3 2 +Notch signaling pathway 0.3701044386423027 0.1178795074734492 0.9061631306923396 1.0 0.998859869329475 4 Q13573,Q92542,P56545 3 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.2765576071104292 0.066583375314338 0.9469133809493696 1.0 1.0 13 Q14118,O43707,P35221,P50402,P35222,P02545,P16615,Q14126 8 +Melanoma 0.2866207594156124 0.0288970300094129 0.9769467143433188 1.0 1.0 9 O00459,P11802,Q9NWH9 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7bd2cc4f016c0191048c35e35b74f163b47967df --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "APPL1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "ATRX", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHA", "BCR", "BDH2", "BIRC6", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC23", "CDC27", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHERP", "CHMP6", "CHORDC1", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", 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"HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "JAM3", "JUP", "KARS", "KDSR", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LSM2", "LSM6", "LSS", "LTA4H", "LYN", "LYPLA1", "M6PR", "MAD2L1", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MPV17", "MRE11", "MRPL13", "MSH2", "MSH3", 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sha256:9bc710d2025ae988fd7bc691c01b89cf1ce67d9b0b2967b3965087ba10346936 +size 132922 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3a98367bc5eb6168c22c88b3fba124c349578604 --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b286a88c3f0552a41692e8f3eff7ea8d69c9d99bcb7325f3691a0ef8fb98ad6 +size 139025 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..317bfdab5072931a1cfcdfcb5616392fbf4de804 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:789a56f675a06071ed120810b2016e10396417b1011770b5741deae1ea6c36bb +size 96228 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bfa429a073fb6e1b453ab489a0bc30d7e5a2df2a --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,17 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protein localization 24 77 4.062063965959046 4.864074386579098e-05 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 0.0001881774213103 4.617737056066913e-06 9.849004725073229e-07 2.2386093541930163e-11 5.229920309203963e-12 +Mitochondrial protein import 13 36 3.1266398479914512 0.0017681638691473 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 9.510982775869628e-06 3.337030564293234e-07 8.081545244431965e-08 1.2200536142307242e-08 8.772185629313841e-08 +Mitochondrial calcium ion transport 5 17 2.933797420305607 0.0033484267461922 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.0006904556096369 0.0044823878286489 4.236608354872846e-05 7.429749655930552e-06 0.0003689915939861 +Processing of smdt1 3 12 2.427754205426577 0.015192635730886 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.1268321491559422 0.0742352733278267 0.0100519320580488 0.0004788146962384 0.0062633876942655 +Pink1 prkn mediated mitophagy 2 8 2.3713165202630413 0.0177248446886073 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.1342086162653788 0.0029386578360865 0.0113213926532688 0.0073447144383531 0.0465653262864464 +Mitophagy 2 11 2.3035477439993226 0.0212480441173581 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.1841473397688249 0.0058373227860703 0.0219975904219434 0.0193169154759243 0.1083207684216986 +Organelle biogenesis and maintenance 16 89 2.2924496834832624 0.0218797078699635 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.0254758465952818 0.1375128720141114 0.0441471348315453 0.0291492250803966 0.0627883074349251 +Sphingolipid de novo biosynthesis 4 11 2.2509371557851905 0.0243895179983661 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.2180640977807147 0.1305522111527444 0.031373049189738 0.0319451393300601 0.0119362160344991 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 5 14 2.2107029215028886 0.0270564160968844 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 0.0808371049858734 1.0 0.1009015630926116 0.1524764865133537 0.0531216479129258 +Transport of inorganic cations anions and amino acids oligopeptides 8 11 2.1176860355120035 0.0342016662964719 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0529437310717216 0.1913705796369965 0.0666692325567911 0.2871762535363917 0.0605931687414638 +Cell surface interactions at the vascular wall 7 18 2.1042751237450195 0.0353544547276982 4.95873786407767 15.691747572815531 0.5051863749151446 0.4839549723278067 2.507415479651395 2.585363930808798 0.9576767064205626 0.3154426595544552 1.0 1.0 1.0 0.2385176558358965 0.4437143289312975 +Depolymerisation of the nuclear lamina 4 11 2.093918756293608 0.0362672181353764 3.5509708737864076 9.264563106796116 0.3528590781344482 0.4868013249239434 1.8459675362212444 0.9401541669683848 0.9887999500170416 0.3159648114925705 1.0 1.0 1.0 0.0061570039439817 0.0007388687073799 +Peptide ligand binding receptors 1 6 2.0791131586808618 0.0376069509239664 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.1342086162653788 0.0786913117950012 0.1515272625734178 0.0621585272883563 0.1985866733922443 +Class a 1 rhodopsin like receptors 1 6 2.0791131586808618 0.0376069509239664 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.1631035739222515 0.0963063052639835 0.1837383274168749 0.0901924811619011 0.2715157705871365 +Phase i functionalization of compounds 3 15 2.040796158833223 0.0412710925422885 3.5364077669902914 14.184466019417476 1.0829555250605305 0.2802752482018614 1.63283502003666 1.0657744603346575 1.0337417132355466 0.2758879448139676 0.004253327563809 0.01497108596825 0.0061250241039257 0.0140312853386763 0.0390278099301106 +Class i peroxisomal membrane protein import 7 11 2.01931935592771 0.0434540373590424 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 0.1487772667192279 0.0875404472016038 0.1677870330809631 0.0101015401572799 0.000200465132953 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9a2c1afcf626e1f20cb798245967daa8c0af544b --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 1388, + "title": "Average number of proteins per term", + "value": 18.946685878962537 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f301a4a4191a28e504c6db82b70b01ee621ae85e --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46759260a3c1de52bdab4a14a2dab52073f444bb --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,404 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.6034416713554787 4.062063965959046 4.864074386579098e-05 0.0652862950432385 0.0675133524857192 77 Q99595,O75431,O60830,P34913,Q5JRX3,O14975,Q9NX63,Q15067,P21796,Q13505,P62072,Q9NS69,Q8N4H5,Q9NR77,O15254,Q13011,O75381,O75874,P56589,Q10713,P10809,P50402,Q9Y584,Q9BY49 24 +Mitochondrial protein import 0.7563892709231194 3.1266398479914512 0.0017681638691473 0.9142555343375371 0.46476163237149 36 O75431,Q99595,O60830,Q13505,P62072,Q9NS69,Q8N4H5,Q5JRX3,P10809,Q9Y584,Q9NX63,P21796,Q10713 13 +Mitochondrial calcium ion transport 0.7559416663033701 2.933797420305607 0.0033484267461922 0.990490032676895 0.46476163237149 17 Q8IYU8,P45880,P21796,Q10713,Q9H4I9 5 +Processing of smdt1 0.7439897906780797 2.427754205426577 0.015192635730886 0.9999999994090004 0.9882711984862012 12 Q8IYU8,Q10713,Q9H4I9 3 +Pink1 prkn mediated mitophagy 0.8228978332459793 2.3713165202630413 0.0177248446886073 0.9999999999834184 0.9882711984862012 8 P21796,Q9NS69 2 +Mitophagy 0.7425375458462475 2.3035477439993226 0.0212480441173581 0.9999999999998868 0.9882711984862012 11 P21796,Q9NS69 2 +Organelle biogenesis and maintenance 0.4178666665545016 2.2924496834832624 0.0218797078699635 0.9999999999999538 0.9882711984862012 89 O95684,O75431,Q13505,P48735,O43805,O75964,Q9H6D7,Q7Z4H7,P00846,O75935,P17252,Q9NX63,A6NIH7,Q9UPT5,P41208,Q10713 16 +Sphingolipid de novo biosynthesis 0.731909057627733 2.2509371557851905 0.0243895179983661 0.9999999999999988 0.9882711984862012 11 Q06136,Q96G23,P51648,O15121 4 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6749763955012427 2.2107029215028886 0.0270564160968844 1.0 0.9882711984862012 14 Q15293,Q9BTY2,Q02818,Q07065,O43852 5 +Transport of inorganic cations anions and amino acids oligopeptides 0.7052696456133523 2.1176860355120035 0.0342016662964719 1.0 0.9943104522779792 11 Q9Y666,P30626,Q70HW3,P08195,Q15758,Q9Y6M7,P30825,Q9UBX3 8 +Cell surface interactions at the vascular wall 0.5969673978784195 2.1042751237450195 0.0353544547276982 1.0 0.9943104522779792 18 O00459,Q9UNN8,P08195,Q92896,Q9BX67,P53985,Q08722 7 +Depolymerisation of the nuclear lamina 0.7005591565795641 2.093918756293608 0.0362672181353764 1.0 0.9943104522779792 11 P02545,P05771,P17252,P50402 4 +Peptide ligand binding receptors 0.8390964256990459 2.0791131586808618 0.0376069509239664 1.0 0.9943104522779792 6 P42892 1 +Class a 1 rhodopsin like receptors 0.8390964256990459 2.0791131586808618 0.0376069509239664 1.0 0.9943104522779792 6 P42892 1 +Phase i functionalization of compounds 0.6308053407286381 2.040796158833223 0.0412710925422885 1.0 1.0 15 P07099,P30837,O43169 3 +Class i peroxisomal membrane protein import 0.6858520211642817 2.01931935592771 0.0434540373590424 1.0 1.0 11 Q9NR77,Q5T8D3,P40855,O75381,P56589,P51648,P28288 7 +Cristae formation 0.5664481474658362 1.89933456311069 0.057520501220849 1.0 1.0 19 O75431,Q13505,O75964,P06576,Q16891,P00846,Q9NX63,P24539 8 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6542563016830633 1.8570822702286112 0.0632994502420034 1.0 1.0 11 P46379,P50402,O43765,Q7L5D6,P51648 5 +Gpcr ligand binding 0.6829604577709756 1.812478972077604 0.0699122201874022 1.0 1.0 9 Q9UBI6,P42892,P07602,P63218 4 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.73292810439188 1.7899021339798185 0.0734696457383097 1.0 1.0 7 Q9NR77 1 +Nucleotide salvage 0.6952732935547246 1.7867747371303668 0.0739739040314193 1.0 1.0 8 P00813 1 +Mitotic g2 g2 m phases 0.3768090038735103 1.7603095260410166 0.0783553398851557 1.0 1.0 88 O95684,P28070,P28072,O43805,P49721,Q96CV9,Q9H6D7,Q7Z4H7,O14974,O75935,P20618,P28074,P17252,Q99436,P41208,Q13561 16 +Formation of fibrin clot clotting cascade 0.9356217842414922 1.71370379094062 0.0865831403302586 1.0 1.0 3 P42785 1 +Slc mediated transmembrane transport 0.5439158852352826 1.6913718235205597 0.0907658102324371 1.0 1.0 26 Q9Y666,Q8TAD4,Q99808,Q70HW3,Q15043,Q9Y6M7,P30825,P53985,Q9UBX3 9 +Rho gtpases activate pkns 0.5334545364914705 1.6854105848277916 0.0919093828673325 1.0 1.0 19 P84243,P63104,P62258,P16104,P31946,O14974,Q9Y3B8,Q04917 8 +Activation of bh3 only proteins 0.6365576187977972 1.670655072221538 0.0947898278264842 1.0 1.0 10 P63104,P62258,P31946,P61981,P63167,Q9Y3B8,P04637,Q04917 8 +Ire1alpha activates chaperones 0.5361808412414015 1.6701440586764766 0.0948908648894444 1.0 1.0 22 P43307,Q9Y5M8,Q13217,P02545,Q9NWM8,P51858 6 +Amino acid transport across the plasma membrane 0.7412503639639465 1.662558551972857 0.0964008336837642 1.0 1.0 5 P08195,P30825,Q15758 3 +Pre notch expression and processing 0.7040894852964017 1.6606814331251418 0.0967774442823199 1.0 1.0 7 Q9HCE1,P16104,P84243,P16615 4 +Purine salvage 0.7378855967048992 1.648310734354173 0.0992889231093592 1.0 1.0 5 P00813 1 +Heparan sulfate heparin hs gag metabolism 0.7340612007161189 1.63209857877162 0.1026587211217888 1.0 1.0 5 Q7LGA3,P54802,P16278 3 +Ca2 pathway 0.6952278799756673 1.6206860830304486 0.1050849798212274 1.0 1.0 7 Q9UBI6,Q08209,P63218,P17252,Q9HCE1 5 +Striated muscle contraction 0.7104146261834907 1.5314573203152315 0.1256564068550481 1.0 1.0 5 Q9NYL9,P67936,P08670,P06753 4 +Aurka activation by tpx2 0.5210826275218196 1.5174969138161634 0.1291412720939007 1.0 1.0 30 O95684,O43805,Q9H6D7,Q7Z4H7,O75935,P17252,P41208 7 +Mucopolysaccharidoses 0.7752392115499229 1.5145490509517603 0.1298866430409324 1.0 1.0 4 P54802,P15586 2 +Vegfr2 mediated cell proliferation 0.7055751063154956 1.5107817850087055 0.1308440570210547 1.0 1.0 5 P05771,P17252 2 +Ion transport by p type atpases 0.6199815132340274 1.5019985176545825 0.133097491657784 1.0 1.0 9 Q9HD20,P30626,P35670 3 +Metabolism of fat soluble vitamins 0.7025647579068918 1.4979087033206806 0.1341569721385727 1.0 1.0 5 Q8N0U8,Q6NUM9 2 +Alpha oxidation of phytanate 0.7701897915749416 1.4944410648888655 0.1350603750988437 1.0 1.0 4 Q9BY49,O14975 2 +Metabolism of steroid hormones 0.6924253692159066 1.4610095507638312 0.1440128204128008 1.0 1.0 6 P30536 1 +Aquaporin mediated transport 0.6581422891247068 1.4520097141131585 0.1464989042208808 1.0 1.0 7 Q9UBI6,P13861,P17252 3 +Anchoring of the basal body to the plasma membrane 0.5113159774009183 1.446297238668076 0.1480938499368043 1.0 1.0 31 O95684,O43805,Q9H6D7,Q7Z4H7,O75935,P17252,P41208 7 +Mrna splicing 0.3922922496987955 1.4366113562104834 0.1508284549967564 1.0 1.0 135 Q9Y5S9,Q8N684,O75940,P84103,P62312,Q8IWZ8,Q08170,Q15717,Q13242,P52597,Q14103,P55795,Q92733,P61978,Q13151,P08621,P67809,Q9BUJ2,Q86U42,Q9NW64,Q07955,O75934,P51991,P52756,O95400,P22626,Q9P013,P09012,Q86V81,P31943,O75494,O43390,Q6UN15,P35637,Q96I25,Q16629,P62995,P07910,P38159,P09651 40 +Abc transporters in lipid homeostasis 0.8551386623164698 1.4142751683968795 0.1572811249097665 1.0 1.0 3 P56589,P40855 2 +Pregnenolone biosynthesis 0.7492073329406339 1.4106996736662143 0.1583331872516598 1.0 1.0 4 P30536 1 +Anti inflammatory response favouring leishmania parasite infection 0.5424506896066407 1.4035819923395942 0.1604433605376471 1.0 1.0 13 O43865,Q9UBI6,P13861,P17252 4 +Endosomal vacuolar pathway 0.7425169119304793 1.383946323128778 0.1663748911653377 1.0 1.0 4 Q9UIQ6 1 +Fcgr3a mediated il10 synthesis 0.6359921576669397 1.3504296445575434 0.176878207191816 1.0 1.0 7 O43865,P17252 2 +Vasopressin regulates renal water homeostasis via aquaporins 0.6626053006401503 1.3318809085561396 0.1828993254881781 1.0 1.0 6 Q9UBI6,P13861,P17252 3 +Glucagon signaling in metabolic regulation 0.6626053006401503 1.3318809085561396 0.1828993254881781 1.0 1.0 6 Q9UBI6,P13861,P17252 3 +Mrna decay by 3 to 5 exoribonuclease 0.518459578194359 1.3190916824583356 0.1871384635080411 1.0 1.0 14 Q969T7,Q15024,Q9Y450,Q13868 4 +Sirt1 negatively regulates rrna expression 0.6600725563176594 1.3153997177139656 0.1883756003546044 1.0 1.0 5 P84243 1 +Disinhibition of snare formation 0.7219592680979796 1.3016389146601377 0.1930398503959876 1.0 1.0 4 P17252 1 +Negative regulation of met activity 0.6219151355764543 1.2856358356192887 0.1985701840474876 1.0 1.0 7 Q92783,P42566,O14964 3 +Muscle contraction 0.4823347281851711 1.261737517464918 0.2070432520780603 1.0 1.0 27 P30626,P06753,P67936,O43865,P16615,P17252,P08133,P08670,P04083 9 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.5255065370080128 1.259179685174924 0.2079654374726551 1.0 1.0 12 Q03164,Q9HCE1,P84243,Q9UBL3 4 +Rhoa gtpase cycle 0.4774821103730102 1.2457758992652677 0.2128466799434729 1.0 1.0 44 O00459,Q15904,P41440,Q86UP2,Q9H0H5,P30519,Q96RT1,P51572,Q5T8D3,Q14739,Q96HY6,P28288,O15173 13 +Synaptic adhesion like molecules 0.5796061608170875 1.2279787457615403 0.2194549467620423 1.0 1.0 8 O95197,P41440 2 +Recruitment of mitotic centrosome proteins and complexes 0.4808642631176759 1.2268615050607314 0.2198746491483469 1.0 1.0 32 O95684,O43805,Q9H6D7,Q7Z4H7,O75935,P17252,P41208 7 +Transport of bile salts and organic acids metal ions and amine compounds 0.6379494456466369 1.2246969866703548 0.2206894099122029 1.0 1.0 6 P53985,Q8TAD4 2 +Thromboxane signalling through tp receptor 0.6345278226490463 1.205267431488147 0.2281000782015336 1.0 1.0 5 Q14344,Q9UBI6,P63218 3 +The citric acid tca cycle and respiratory electron transport 0.3425954838263254 1.196206134498989 0.2316161275425947 1.0 1.0 96 Q13423,P48735,Q86Y39,Q8N183,P00403,O75964,O96000,O43676,P00846,P22695,Q9UDW1,Q9Y6M9,P21796,P53985,P03915 15 +Role of phospholipids in phagocytosis 0.631856960368107 1.1937502706404854 0.2325756696105636 1.0 1.0 5 O43865,Q8IV08 2 +Listeria monocytogenes entry into host cells 0.5721249148839602 1.1912530543958528 0.2335542574357965 1.0 1.0 8 Q92783,P42566,Q9NWH9,O14964,O60716 5 +Regulation of plk1 activity at g2 m transition 0.475486168803963 1.1842444681170126 0.2363163040635638 1.0 1.0 35 O95684,O43805,Q96CV9,Q9H6D7,Q7Z4H7,O75935,P17252,P41208,Q13561 9 +Sulfur amino acid metabolism 0.5419006730048537 1.181392758442694 0.2374467334479839 1.0 1.0 10 Q13126 1 +Glycosaminoglycan metabolism 0.5108167999105149 1.1771904016154848 0.2391195188404991 1.0 1.0 12 Q7LGA3,P54802,P15586,Q8TB61,P16278,O43252,O94923 7 +Basigin interactions 0.5981147248917493 1.1758348677044108 0.2396608701144442 1.0 1.0 7 P53985 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.6227839961271155 1.1587047565756845 0.2465765513239706 1.0 1.0 6 Q92783,P42566,O14964 3 +Protein protein interactions at synapses 0.4725995730526028 1.1583954425064094 0.2467026981668776 1.0 1.0 16 Q14168,O14936,P41440,O95197,Q96HC4,P10586 6 +Peroxisomal protein import 0.457530957375843 1.1534499236288038 0.2487257602667414 1.0 1.0 21 P34913,Q9BY49,O15254,Q13011,O75381,O75874,Q15067 7 +Platelet calcium homeostasis 0.6830483398842726 1.1458019415917635 0.2518771116323679 1.0 1.0 4 P30626 1 +Ptk6 regulates proteins involved in rna processing 0.779119086460021 1.1302855044373672 0.2583559405658926 1.0 1.0 3 O75525,P23246 2 +Prevention of phagosomal lysosomal fusion 0.6715939797222815 1.1000349460921477 0.2713168960209107 1.0 1.0 4 O14964,Q9H267 2 +Syndecan interactions 0.6078061232946913 1.0901466423287176 0.2756485530559014 1.0 1.0 5 P17252 1 +Recruitment of numa to mitotic centrosomes 0.461756501183366 1.0837587684062628 0.2784717710233293 1.0 1.0 35 O95684,O43805,Q9H6D7,Q7Z4H7,O75935,P17252,P41208 7 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.577353065681995 1.0800020476191887 0.2801412683593933 1.0 1.0 7 Q9UBI6,P13861,P17252 3 +G alpha i signalling events 0.448959928167778 1.070361354449156 0.2844566873382765 1.0 1.0 23 Q9UBI6,P07602,P52292,P30154,P63218,O43865,P17252,P13861 8 +Cholesterol biosynthesis 0.4671384519955541 1.0673497433847967 0.2858139335217782 1.0 1.0 15 Q15392,Q15126,Q9BWD1,Q16850,Q14534 5 +Biosynthesis of specialized proresolving mediators spms 0.7621533442087973 1.0673148249197024 0.2858296958896695 1.0 1.0 3 P34913,P09960 2 +Reduction of cytosolic ca levels 0.7617365308314964 1.0657715571537802 0.2865269213598327 1.0 1.0 3 P30626 1 +Selective autophagy 0.4546919216812489 1.061748577065441 0.2883498401355147 1.0 1.0 28 P21796,Q9NS69,P08670 3 +Deubiquitination 0.3249351251078254 1.0612737164263673 0.2885655268719647 1.0 1.0 87 P28070,P28072,P49721,P45880,P20618,P85037,P21796,Q99436 8 +Insulin receptor recycling 0.5188474385556081 1.061074715036826 0.2886559477413526 1.0 1.0 10 Q15904,P36543,Q93050,Q9Y487 4 +Adora2b mediated anti inflammatory cytokines production 0.5322451474908393 1.0598117858181644 0.2892302338909092 1.0 1.0 9 P13861,Q9UBI6,P63218,P17252 4 +Metabolism of porphyrins 0.5182651707686586 1.0580383524527068 0.2900379577272578 1.0 1.0 10 P22830,P30519,P50336 3 +Hs gag degradation 0.7595869783542806 1.0578160035579147 0.2901393352540156 1.0 1.0 3 P54802 1 +Integrin cell surface interactions 0.5998137915046768 1.0557991193115417 0.2910600006853379 1.0 1.0 5 P05556,Q9BX67,Q08722 3 +Transport of small molecules 0.3815216297691074 1.0342558671208684 0.3010165627830947 1.0 1.0 161 Q15904,P28072,Q70HW3,Q15043,Q8TB61,P30825,P30519,Q8TDW0,O75477,Q93050,P21796,Q99436,Q9H4I9,P28070,Q8TAD4,P49721,P35610,P28074,P08183,Q8WTV0,P17252,P40855,P56589,Q9UBX3,Q10713,P28288,Q9Y666,Q9UBI6,O15439,Q9HD20,Q9Y6M7,P45880,P53985,Q8IYU8,Q99808,Q9BPX6,P36543,Q9Y4W6,P20618,O15118,Q92530 41 +G2 m checkpoints 0.3217377254320337 1.00805770621272 0.3134267600162363 1.0 1.0 80 P28070,P28072,P49721,P20618,Q9Y3B8,Q99436 6 +G alpha z signalling events 0.5616026676822791 1.007430758041531 0.3137278166215393 1.0 1.0 7 P05771,Q9UBI6,P17252 3 +Citric acid cycle tca cycle 0.4385406436724852 1.0042861923886774 0.3152406870457849 1.0 1.0 17 Q13423 1 +Transferrin endocytosis and recycling 0.4936674132319553 1.0017879569117902 0.316446014933365 1.0 1.0 11 Q15904,P36543,Q93050,Q9Y487 4 +Antigen processing cross presentation 0.4357412126866107 1.0010458291657942 0.3168046524384964 1.0 1.0 51 P28070,P28072,P49721,Q9UIQ6,P20618,Q99436 6 +Cilium assembly 0.4152047861816498 0.9987300682324726 0.3179254707152128 1.0 1.0 59 O95684,O43805,Q9H6D7,Q7Z4H7,O75935,P17252,A6NIH7,Q9UPT5,P41208,Q10713 10 +Dag and ip3 signaling 0.5194833287075244 0.9953429717924664 0.3195694846626069 1.0 1.0 9 P52292,O43865,P17252 3 +Response to elevated platelet cytosolic ca2 0.4491527051207304 0.9917316266061988 0.3213284588457066 1.0 1.0 35 P07602,O15439,Q8NBX0,P17252,Q9Y6I9,O43852 6 +Initiation of nuclear envelope ne reformation 0.4454838497798074 0.989241862884934 0.3225448208761308 1.0 1.0 16 P02545,Q86XL3,P50402 3 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.5160276182921048 0.977913916832681 0.3281169014430822 1.0 1.0 9 O60725,Q9BU89 2 +Regulation of insulin secretion 0.4668333509203993 0.971036734872295 0.3315299859739684 1.0 1.0 13 O43865,Q9UBI6,P13861,P17252 4 +Smooth muscle contraction 0.4842183733775044 0.9510790240224556 0.3415642619863579 1.0 1.0 11 P67936,P08133,P06753 3 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7271191982151737 0.938458281759131 0.3480089466153431 1.0 1.0 3 Q8NB78 1 +Pka mediated phosphorylation of creb 0.6286986724281646 0.9298859403870244 0.3524301432526087 1.0 1.0 4 P17252 1 +Creb1 phosphorylation through the activation of adenylate cyclase 0.6286986724281646 0.9298859403870244 0.3524301432526087 1.0 1.0 4 P17252 1 +Pka activation in glucagon signalling 0.6286986724281646 0.9298859403870244 0.3524301432526087 1.0 1.0 4 P17252 1 +Class b 2 secretin family receptors 0.723980424143547 0.9270163053756756 0.3539180685088978 1.0 1.0 3 Q9UBI6,P63218 2 +Signal amplification 0.543568873451709 0.9246657734240888 0.3551397882185574 1.0 1.0 7 Q14344,P04899,Q9UBI6,P63218 4 +Apoptotic cleavage of cellular proteins 0.4171900196199674 0.91235277565246 0.3615830406582618 1.0 1.0 19 P02545,P49354,P51572,P20700,P08670 5 +O linked glycosylation 0.5643829505656619 0.905813407148436 0.3650346234510149 1.0 1.0 6 Q10472,Q8NAT1 2 +Maturation of sars cov 2 spike protein 0.4756697878347772 0.9053568063163536 0.3652763908274519 1.0 1.0 11 P46977,P04843,P04844,Q16706 4 +Cell death signalling via nrage nrif and nade 0.5386141972421297 0.9020168305291656 0.3670479272171474 1.0 1.0 7 Q14344,P62258,Q9NY61,Q92542 4 +Fgfr2 alternative splicing 0.4604382410976967 0.8969572432165359 0.3697417327770993 1.0 1.0 12 P52597,P09651,P31943 3 +Mitochondrial biogenesis 0.4312886921496354 0.8841638852268492 0.3766077507058682 1.0 1.0 30 O75431,Q13505,P48735,O75964,P00846 5 +Non integrin membrane ecm interactions 0.5335767194571241 0.8790395712167546 0.3793798205141852 1.0 1.0 7 P17252 1 +Egfr downregulation 0.5320274313696914 0.8719839584191647 0.383217128899378 1.0 1.0 7 Q92783,P42566,O14964 3 +Collagen biosynthesis and modifying enzymes 0.464176338082482 0.8441923419360378 0.3985619331925236 1.0 1.0 11 Q32P28,O75718 2 +Ion homeostasis 0.4504496357760924 0.8420253520136234 0.3997737629321447 1.0 1.0 12 O43865,P30626,P17252 3 +G protein mediated events 0.4491336899515438 0.834815379826127 0.4038216650153026 1.0 1.0 12 P52292,O43865,P17252 3 +Transcriptional regulation by runx1 0.3580155382899362 0.8311694034601296 0.4058779367583334 1.0 1.0 70 P28070,P28072,P84243,P49721,Q03164,P28074,Q9HCE1,P20618,P05771,Q969G3,Q99436 11 +Synthesis of bile acids and bile salts 0.521701419391728 0.8251086930337204 0.409309884827556 1.0 1.0 7 Q9H4L5 1 +Bile acid and bile salt metabolism 0.521701419391728 0.8251086930337204 0.409309884827556 1.0 1.0 7 Q9H4L5 1 +Abc family proteins mediated transport 0.4085198592863868 0.8219689512611359 0.4110945681300149 1.0 1.0 54 P28070,P28072,P49721,O15439,P20618,P08183,Q99436 7 +Unfolded protein response upr 0.4256233456136989 0.8180916051894843 0.4133048820065332 1.0 1.0 38 Q13868,Q9Y5M8,Q92945,Q13217,P02545,P43307,Q9NWM8,P51858,Q15024 9 +Formation of atp by chemiosmotic coupling 0.4715046567463157 0.8158964115156302 0.4145593847233568 1.0 1.0 10 P00846 1 +Rhof gtpase cycle 0.408113772663207 0.8102692236476672 0.4177854596098986 1.0 1.0 17 O00459,Q5JTV8,Q07960,P80723,Q8TAA9,Q9Y6M7,P42167,P20700 8 +Cardiac conduction 0.4383436853956467 0.809895357110287 0.4180003205156053 1.0 1.0 13 O43865,P30626,P17252 3 +Diseases associated with n glycosylation of proteins 0.5413129412857184 0.8075059582408293 0.419375043168017 1.0 1.0 5 Q2TAA5 1 +Opioid signalling 0.4008521125429453 0.8047026980714689 0.4209912622554421 1.0 1.0 19 Q9UBI6,P52292,P30154,O43865,P17252,P13861 6 +Cytoprotection by hmox1 0.3741146838432383 0.794600161053112 0.4268461246344193 1.0 1.0 65 P28070,P28072,P00403,P49721,P30519,P20618 6 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4184460488571163 0.7830352166702454 0.4336064319882942 1.0 1.0 44 P28070,P28072,P84243,P49721,Q03164,P20618,Q99436 7 +Hur elavl1 binds and stabilizes mrna 0.5110945614376157 0.7772746466801451 0.4369967498243707 1.0 1.0 7 Q01105,P17252 2 +Met activates ras signaling 0.5890694912189097 0.7759351627380334 0.4377872696447995 1.0 1.0 4 Q9NWH9 1 +G beta gamma signalling through cdc42 0.5865166611595531 0.7661783231574899 0.4435702045515453 1.0 1.0 4 Q9UBI6 1 +G protein beta gamma signalling 0.5865166611595531 0.7661783231574899 0.4435702045515453 1.0 1.0 4 Q9UBI6 1 +Apoptosis 0.3049546486125156 0.7632603440127891 0.445308147105655 1.0 1.0 89 P28070,P28072,P49721,P02545,P20618,P49354,P28074,Q9Y3B8,P51572,P20700,Q9NR28,Q99436,P08670 13 +Signaling by vegf 0.4098889306391 0.7615810710549362 0.4463100758303384 1.0 1.0 27 P46108,P17252,P05771,Q96F07,Q9UQB8 5 +Rhobtb1 gtpase cycle 0.3953806000285498 0.7533045601529412 0.4512669191574825 1.0 1.0 20 P62995,P07910,P38159,P78371,P08670 5 +Interleukin 3 interleukin 5 and gm csf signaling 0.4701065760033262 0.7486985272286475 0.4540389315505853 1.0 1.0 9 O00459,P46108,P17252 3 +Robo receptors bind akap5 0.6739307629667296 0.7479090656078583 0.4545150090098444 1.0 1.0 3 P17252 1 +Regulation of mecp2 expression and activity 0.4581479799592247 0.7478542021181539 0.4545481043758497 1.0 1.0 10 Q9HCE1,P17252,Q96GD4 3 +Ksrp khsrp binds and destabilizes mrna 0.4456778952014125 0.7467692494580781 0.4552028605097846 1.0 1.0 11 P63104,Q13868,O95453,Q92945,Q15024 5 +Diseases of dna repair 0.46802740760757 0.7384793616386428 0.4602232040742942 1.0 1.0 9 Q9UQ84,P20585 2 +Fceri mediated ca 2 mobilization 0.5239825980156931 0.7357507291848767 0.4618824110481077 1.0 1.0 5 O43865 1 +Cargo trafficking to the periciliary membrane 0.3922940243997359 0.7332158380509585 0.463426796967274 1.0 1.0 20 Q96A65,Q9UPT5,A6NIH7,P78371,Q10713,O60645 6 +Nuclear envelope breakdown 0.4121258321571979 0.7254306078078226 0.4681879013931105 1.0 1.0 42 Q8NFH4,Q9BVL2,Q9BW27,P50402,Q99567,Q8NFH5,P12270,P02545,Q8N1F7,P17252,P42167,P05771,P53350,P20700,Q9BTX1,Q12769 16 +Sphingolipid metabolism 0.4038087636384875 0.7206187738210273 0.4711440998354022 1.0 1.0 27 O95470,Q96G23,P07602,P10619,Q06136,O15121,P51648 7 +Rac2 gtpase cycle 0.411871951166341 0.7204865094664005 0.4712255029226173 1.0 1.0 36 O00459,Q13505,P50402,Q8TAA9,Q9H0H5,Q96RT1,P42167,Q14739,Q86XL3,O15173 10 +Nr1h2 and nr1h3 mediated signaling 0.5732809861390349 0.7159834817955698 0.4740015485256537 1.0 1.0 4 Q8NB78 1 +Glycerophospholipid biosynthesis 0.3987780197001843 0.697367295434437 0.4855729631788388 1.0 1.0 26 Q8NCC3,Q8IV08,Q9NPH0 3 +Heme biosynthesis 0.5147371915306451 0.6961728476132297 0.4863205897626033 1.0 1.0 6 P22830,P50336 2 +Disorders of transmembrane transporters 0.3131302562137636 0.6857709618052836 0.4928575503951027 1.0 1.0 77 Q8NFH4,P28070,P28072,P49721,Q8NFH5,P53985,P12270,P20618,P28074,O75477,Q92530,Q8N1F7,Q99436,Q9BTX1,Q12769 15 +Assembly of the orc complex at the origin of replication 0.4570720802646321 0.6849640149544794 0.493366628850894 1.0 1.0 9 Q9Y619,P84243 2 +Cellular response to chemical stress 0.3226896415751397 0.6847850892461557 0.4934795458189871 1.0 1.0 75 P28070,P28072,P00403,P49721,P30519,P20618 6 +Ros and rns production in phagocytes 0.4545911837771488 0.672929544652681 0.5009921150690686 1.0 1.0 9 P36543,Q93050,Q9Y487 3 +Adp signalling through p2y purinoceptor 1 0.6518498520881628 0.671533929918492 0.501880452015699 1.0 1.0 3 Q9UBI6 1 +Adrenaline noradrenaline inhibits insulin secretion 0.6518498520881628 0.671533929918492 0.501880452015699 1.0 1.0 3 Q9UBI6 1 +G protein activation 0.6518498520881628 0.671533929918492 0.501880452015699 1.0 1.0 3 Q9UBI6 1 +Ub specific processing proteases 0.3467864699561454 0.6669512727823655 0.5048032586334992 1.0 1.0 69 P28070,P28072,P49721,P45880,P20618,P21796 6 +Regulation of signaling by cbl 0.5064796854533185 0.6645876529127477 0.506314268655383 1.0 1.0 5 P46108 1 +Sumoylation of transcription factors 0.5589902643368985 0.6626162967658031 0.507576330125729 1.0 1.0 4 P04637,Q12888 2 +Platelet homeostasis 0.4406692132320338 0.6600984989538558 0.5091906218993296 1.0 1.0 10 P30154,P30626,Q9UBI6,P63218 4 +Regulation of runx3 expression and activity 0.4032164065518693 0.6554079434337327 0.5122051385440343 1.0 1.0 38 P49721,P28070,P28072,P20618 4 +Degradation of axin 0.4025670297263264 0.6507643777197943 0.5151985985454832 1.0 1.0 38 P49721,P28070,P28072,P20618 4 +Cross presentation of soluble exogenous antigens endosomes 0.4025670297263264 0.6507643777197943 0.5151985985454832 1.0 1.0 38 P49721,P28070,P28072,P20618 4 +Rhod gtpase cycle 0.3915995748254987 0.6499195967389514 0.5157441590307332 1.0 1.0 26 Q5JTV8,O00459,P50402,Q9Y6M7,Q9H0H5,Q14739,P20700,O15173 8 +Rap1 signalling 0.5515208980584569 0.6351118893942489 0.5253554433158725 1.0 1.0 4 P63104,P17252 2 +Uch proteinases 0.3962880284430739 0.632356635355101 0.5271538634010222 1.0 1.0 47 P28070,P28072,P49721,P20618,P85037,Q99436 6 +Asymmetric localization of pcp proteins 0.3992857192453078 0.626623426388093 0.5309061085758771 1.0 1.0 39 P49721,P28070,P28072,P20618 4 +Mitotic prophase 0.3691607464367086 0.6254907067695212 0.5316490458745715 1.0 1.0 61 P84243,P30154,Q01105,Q9BTX1,Q8NFH5,P17252,P05771,P53350,Q9BVL2,P50402,P12270,P02545,P42167,Q8N1F7,Q12769,Q8NFH4,Q9BW27,Q7Z3B4,Q08379,Q99567,P20700 21 +Ras processing 0.4957703898592152 0.6186600875021107 0.5361403086050354 1.0 1.0 6 O60725 1 +Tp53 regulates metabolic genes 0.3946044593783427 0.6179462760554091 0.5366107531411215 1.0 1.0 32 P00403 1 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3620613023694666 0.6132688014012873 0.5396986187810144 1.0 1.0 63 Q86Y39,Q8N183,P00403,O96000,O75964,O43676,P00846,Q9UDW1,P22695,Q16134,Q9P0J0,Q9Y6M9,P03915 13 +Ca dependent events 0.4519183593274909 0.6095686772659117 0.5421475659908657 1.0 1.0 8 P52292,P17252 2 +Degradation of dvl 0.3967739129166684 0.6086588688693253 0.5427505754331985 1.0 1.0 39 P49721,P28070,P28072,P20618 4 +Signaling by ptk6 0.4067706672757289 0.607710277594823 0.5433796453470263 1.0 1.0 12 P46108,P11802,P23246,O75525,Q8IZL8 5 +Gaba b receptor activation 0.5431400605908416 0.6046041659436836 0.5454420379680005 1.0 1.0 4 Q9UBI6 1 +Gaba receptor activation 0.5431400605908416 0.6046041659436836 0.5454420379680005 1.0 1.0 4 Q9UBI6 1 +Adp signalling through p2y purinoceptor 12 0.5431400605908416 0.6046041659436836 0.5454420379680005 1.0 1.0 4 Q9UBI6 1 +Stabilization of p53 0.3961223327199877 0.6040118248982863 0.5458357804594469 1.0 1.0 39 P49721,P28070,P28072,P20618 4 +Runx1 regulates expression of components of tight junctions 0.6303425774877465 0.5992376088210238 0.5490144466744988 1.0 1.0 3 Q13951,Q16625 2 +Sensing of dna double strand breaks 0.5409278442044909 0.5966174336403826 0.550762829011584 1.0 1.0 4 P52292,P49959 2 +P75 ntr receptor mediated signalling 0.4263804448818502 0.589764308442574 0.5553486743346356 1.0 1.0 10 Q14344,P62258,Q92542,Q9NY61,Q9NQC3 5 +Miro gtpase cycle 0.5363676744206805 0.5802454437198946 0.5617491121801699 1.0 1.0 4 Q8IWA4 1 +Degradation of gli1 by the proteasome 0.3892251420806979 0.558755770169284 0.5763284119017307 1.0 1.0 43 P28070,P28072,P49721,P20618,Q99436 5 +Regulation of mrna stability by proteins that bind au rich elements 0.3523680276063961 0.5502180445238426 0.5821698284859713 1.0 1.0 64 P28070,P28072,Q14103,Q92973,P49721,P63104,Q13868,Q15717,Q92945,P28074,Q01105,P20618,P17252,P49720,Q92530,Q15024,Q99436,P25788 18 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.374286434768281 0.5494321756664798 0.5827088981093336 1.0 1.0 25 Q13126,P52597,P22626 3 +Transcriptional regulation by mecp2 0.3888979298608906 0.5408447737645672 0.5886145789596302 1.0 1.0 13 Q14739,Q9HCE1,P17252,Q96GD4 4 +Metabolism of polyamines 0.3859626813106407 0.5316488352011616 0.5949692347873721 1.0 1.0 40 P49721,P28070,P28072,P20618 4 +Inhibition of dna recombination at telomere 0.4028442419637908 0.5290636911576907 0.5967612679019441 1.0 1.0 11 P46100,P84243 2 +G1 s dna damage checkpoints 0.3855155859408124 0.5285019705360544 0.5971509797475254 1.0 1.0 40 P49721,P28070,P28072,P20618 4 +Cdt1 association with the cdc6 orc origin complex 0.3846873042403302 0.5228082577235781 0.6011076925139092 1.0 1.0 41 P49721,P28070,P28072,P20618 4 +Rhog gtpase cycle 0.383142144996379 0.5201814722018105 0.602937097655067 1.0 1.0 36 P50402,P34897,Q86UP2,Q8TAA9,Q96RT1,P61604,P42167,Q14739,Q86XL3,Q14126,O15173 11 +Intra golgi traffic 0.3790375306384921 0.5169848946761796 0.6051667034387842 1.0 1.0 14 Q8TBA6,O95249,O00461,Q16706 4 +Iron uptake and transport 0.35131987344852 0.5078083072505077 0.6115877833684285 1.0 1.0 18 P30519,Q93050 2 +Ecm proteoglycans 0.6016313213703015 0.5066842132520635 0.6123764091229522 1.0 1.0 3 Q14118,P05556 2 +Met activates ptk2 signaling 0.6016313213702976 0.5066842132520505 0.6123764091229613 1.0 1.0 3 Q9NWH9,P05556 2 +Downstream signaling events of b cell receptor bcr 0.3820103319755429 0.5064947722684856 0.6125093586729409 1.0 1.0 43 P28070,P28072,P49721,P20618,Q99436 5 +Arachidonic acid metabolism 0.4292177025165513 0.5061320841488471 0.6127639285310469 1.0 1.0 8 Q15165,Q8N8N7 2 +Transcriptional regulation by runx3 0.3813233032831519 0.5015640618563224 0.6159742045182988 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Activation of nmda receptors and postsynaptic events 0.3645935328593591 0.5009156464997699 0.6164304903385136 1.0 1.0 24 Q14168,O14936,P52292,P49593,P17252,P07196,Q14012,P13861 8 +Signaling by the b cell receptor bcr 0.3786420799611415 0.4980625844867705 0.6184399312153022 1.0 1.0 47 P28070,P28072,P49721,P28074,P20618,P05771,Q99436 7 +Cellular response to hypoxia 0.3811569423414207 0.4979970462717956 0.6184861240736979 1.0 1.0 40 P49721,P28070,P28072,P20618 4 +Glucagon type ligand receptors 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Presynaptic function of kainate receptors 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Potassium channels 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Inwardly rectifying k channels 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Prostacyclin signalling through prostacyclin receptor 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +G beta gamma signalling through pi3kgamma 0.7873450750163025 0.4953624466245017 0.6203442980608198 1.0 1.0 2 Q9UBI6 1 +Peroxisomal lipid metabolism 0.3835469857431836 0.4893538102447015 0.6245912310605952 1.0 1.0 12 O15254,Q15067,Q9BY49 3 +Negative regulation of nmda receptor mediated neuronal transmission 0.4254325240062048 0.489279641862297 0.6246437320053202 1.0 1.0 8 P07196,Q14012,P49593,Q14168 4 +Signaling by notch 0.3700164990180922 0.485550171342431 0.6272861326305554 1.0 1.0 53 P28070,P28072,P84243,P49721,P67809,P28074,P20618,Q99436 8 +Regulation of ras by gaps 0.3789649633932517 0.4827798790068464 0.6292520389449447 1.0 1.0 40 P49721,P28070,P28072,P20618 4 +Synthesis of very long chain fatty acyl coas 0.4234618555197258 0.4805561473068116 0.630831988915457 1.0 1.0 8 Q9UKU0 1 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.4579254884617418 0.4768922132431685 0.6334388771082469 1.0 1.0 5 P17252 1 +Hedgehog on state 0.3771330910731001 0.4716773504558292 0.637157106254298 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Regulation of glucokinase by glucokinase regulatory protein 0.365309257923098 0.4704485517922546 0.638034583234184 1.0 1.0 27 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Sumoylation of sumoylation proteins 0.365309257923098 0.4704485517922546 0.638034583234184 1.0 1.0 27 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Sumoylation of rna binding proteins 0.3733032395217665 0.4700627129390817 0.6383102129253357 1.0 1.0 33 Q8NFH4,Q9BVL2,Q9BW27,Q99496,Q7Z3B4,P61978,Q8NFH5,Q99567,P12270,P07910,Q8WUM0,P57740,Q8N1F7,Q8IXK0,Q9BTX1,Q12769 16 +Regulation of pten stability and activity 0.3762602548015973 0.4641586080513664 0.6425341142265077 1.0 1.0 42 P49721,P28070,P28072,P20618 4 +Transcriptional regulation by e2f6 0.418789617742077 0.4600174696430961 0.6455036811804893 1.0 1.0 8 Q9UBK9,P45973,Q13185 3 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3752497225954785 0.4583525594764679 0.6466991689595487 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Diseases of mitotic cell cycle 0.3561457358616632 0.4565918403558116 0.6479644451810356 1.0 1.0 16 P11802,P46100,Q96DE5 3 +Transport and synthesis of paps 0.7723418134376956 0.4548065339045161 0.6492484291878617 1.0 1.0 2 Q8TB61 1 +Transcriptional regulation of granulopoiesis 0.4077897698100391 0.4539732819863472 0.649848057239705 1.0 1.0 9 Q03164,P84243 2 +Interleukin 12 signaling 0.362652949149474 0.4539711328192687 0.6498496041253161 1.0 1.0 27 Q13126,P52597,P22626 3 +Sumoylation of ubiquitinylation proteins 0.3642216768484697 0.4533799751142957 0.6502751533839364 1.0 1.0 28 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Hs gag biosynthesis 0.7716894977168812 0.4530763740839578 0.6504937471798693 1.0 1.0 2 Q7LGA3 1 +Nrage signals death through jnk 0.4506729611188498 0.4504409509330205 0.6523925227281218 1.0 1.0 5 Q14344,Q9NY61 2 +Cytochrome p450 arranged by substrate type 0.5823717782555687 0.4476278515751431 0.654421799150235 1.0 1.0 3 Q16850 1 +Mapk6 mapk4 signaling 0.3657044590547847 0.4403948182826879 0.6596511772204787 1.0 1.0 52 P28070,P28072,P49721,P28074,P20618,P17252,Q99436 7 +Condensation of prophase chromosomes 0.3944832197952159 0.4390561459571244 0.6606208541340965 1.0 1.0 10 P53350,Q01105,P84243 3 +Negative regulation of notch4 signaling 0.3717677988046023 0.4334476550429676 0.6646895861621687 1.0 1.0 40 P49721,P28070,P28072,P20618 4 +G alpha 12 13 signalling events 0.4292704208517631 0.4275745035841732 0.6689609319355279 1.0 1.0 7 Q14344,Q13464,Q9UBI6,P63218 4 +Synthesis of leukotrienes lt and eoxins ex 0.7619047619047588 0.4274695018613126 0.6690373942404895 1.0 1.0 2 P09960 1 +Zinc transporters 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 1.0 3 Q8TAD4 1 +Metal ion slc transporters 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 1.0 3 Q8TAD4 1 +Signaling by insulin receptor 0.3495624647128064 0.4207312365865678 0.6739513489054039 1.0 1.0 16 O00459,Q15904,P36543,Q9Y487,Q93050 5 +Pcp ce pathway 0.3638523053622922 0.4165823720965399 0.6769839053530273 1.0 1.0 51 P28070,P28072,P49721,P20618,P17252,Q99436 6 +Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.4401119207254724 0.4128252287272146 0.6797346659818952 1.0 1.0 5 P84243 1 +Rna polymerase i promoter escape 0.3668547395352985 0.4082717700230491 0.683074162300608 1.0 1.0 12 Q13185,P84243 2 +Hedgehog ligand biogenesis 0.3669409838869095 0.3999560049717009 0.6891889211749556 1.0 1.0 41 P49721,P28070,P28072,P20618 4 +O linked glycosylation of mucins 0.4808356373406524 0.3928534376998789 0.694427733569766 1.0 1.0 4 Q10472 1 +Rac3 gtpase cycle 0.3611698981075794 0.3926759129506867 0.6945588632334014 1.0 1.0 33 O00459,Q9UQB8,P50402,Q8TAA9,Q9H0H5,Q96RT1,P42167,Q14739,Q14126,O15173 10 +Signaling by notch4 0.36578847713519 0.3919462439338675 0.6950979333598415 1.0 1.0 42 P49721,P28070,P28072,P20618 4 +Ns1 mediated effects on host pathways 0.3617155166695081 0.3897419459605973 0.6967273759731043 1.0 1.0 34 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,P52292,Q99567,Q8NFH5,P12270,Q86U42,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 14 +Notch4 activation and transmission of signal to the nucleus 0.7452707110241328 0.3854884025321407 0.699875597278941 1.0 1.0 2 P63104 1 +Respiratory electron transport 0.3571524755802965 0.3849648137227028 0.7002634848488207 1.0 1.0 53 Q86Y39,Q8N183,P00403,O96000,O43676,Q16134,Q9UDW1,P22695,Q9P0J0,Q9Y6M9,P03915 11 +Atf4 activates genes in response to endoplasmic reticulum stress 0.3704151050694411 0.376168205065667 0.7067918511175277 1.0 1.0 11 Q13868,Q92945 2 +Tp53 regulates transcription of genes involved in cytochrome c release 0.7407045009784632 0.3743215477086052 0.7081651026887759 1.0 1.0 2 Q9Y255 1 +Biological oxidations 0.3631149856233304 0.3742907471619351 0.7081880153245788 1.0 1.0 43 P07099,Q9NUJ1,P30837,O43169 4 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3564220637758165 0.3695809801426699 0.7116947248803909 1.0 1.0 52 P28070,P28072,Q96DE5,P49721,P20618,Q96GD4,Q99436 7 +Signaling by fgfr2 0.3270567171755241 0.3666212662619008 0.713901543004273 1.0 1.0 18 P52597,P31943 2 +Signaling by fgfr 0.3270567171755241 0.3666212662619008 0.713901543004273 1.0 1.0 18 P52597,P31943 2 +Circadian clock 0.3782008463841148 0.366526562659694 0.7139721954317126 1.0 1.0 10 P43490 1 +Fceri mediated nf kb activation 0.3614414363418626 0.3629627023320533 0.7166327462719384 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Suppression of phagosomal maturation 0.4120548965631955 0.3608971374172984 0.7181763435925681 1.0 1.0 7 O14964,Q9H267 2 +The role of gtse1 in g2 m progression after g2 checkpoint 0.3578102776230473 0.3571504533728933 0.7209791754647201 1.0 1.0 49 P49721,P28070,P28072,P20618 4 +Rho gtpases activate nadph oxidases 0.3923998071086321 0.3483334843765989 0.7275897496927375 1.0 1.0 8 P17252 1 +Postmitotic nuclear pore complex npc reformation 0.3355994755828223 0.341810198455025 0.7324937341157616 1.0 1.0 23 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q8NFH5,Q8WUM0,P57740,Q92973,Q8N1F7,Q9BTX1,Q12769 11 +Abc transporter disorders 0.3576939320101167 0.337851803528939 0.7354748692236281 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Defective cftr causes cystic fibrosis 0.3576939320101165 0.3378518035289384 0.7354748692236286 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Darpp 32 events 0.3805683565431946 0.3365754747328555 0.7364369468844219 1.0 1.0 9 P17252,P13861 2 +Visual phototransduction 0.3801767082938166 0.3349567723910638 0.737657695036612 1.0 1.0 9 P49354,P17252,Q6NUM9 3 +Phospholipid metabolism 0.3555005198347237 0.3284801333779537 0.7425486629974112 1.0 1.0 39 Q10713,Q8NCC3,Q9NPH0 3 +Processing of capped intron containing pre mrna 0.3376234719561842 0.3252379548686122 0.7450009849759782 1.0 1.0 177 Q9Y5S9,Q8N684,O75940,P84103,P62312,Q8IWZ8,Q15717,P82979,Q9BTX1,Q13242,P52597,Q14103,P55795,Q92733,P61978,Q13151,Q8NFH5,P67809,P08621,Q9BUJ2,Q86U42,Q9NW64,Q07955,O75934,P51991,P52756,O95400,P22626,Q9P013,P09012,P12270,Q86V81,Q8N1F7,P31943,Q12769,Q8NFH4,O75494,O43390,Q6UN15,P35637,Q99567,Q96I25,Q16629,P62995,P07910,P38159,P09651 47 +Sumoylation of dna replication proteins 0.3522329313877365 0.3251008336295257 0.7451047580537258 1.0 1.0 35 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,P57740,Q53HL2,Q8WUM0,Q96GD4,Q8N1F7,Q9BTX1,Q12769 14 +Oxidative stress induced senescence 0.3447850051839093 0.323613538122996 0.7462306371475635 1.0 1.0 13 P84243,P11802,P16104,Q8IXK0,Q9HCE1,P04637 6 +Cohesin loading onto chromatin 0.3861099106764198 0.3229537399691208 0.7467302764466495 1.0 1.0 8 Q9Y6X3,Q8WVM7 2 +Scf skp2 mediated degradation of p27 p21 0.3539140960299813 0.3131464846396369 0.7541693741100821 1.0 1.0 42 P49721,P28070,P28072,P20618 4 +Clec7a dectin 1 induces nfat activation 0.7038486627527566 0.2902633881284823 0.771614745706138 1.0 1.0 2 O43865 1 +Programmed cell death 0.2769136548445937 0.2901766663210938 0.7716810861811725 1.0 1.0 99 P28070,P28072,P41440,P49721,P02545,P20618,P49354,P28074,Q9Y3B8,P51572,P20700,Q9NR28,Q99436,P08670 14 +Polo like kinase mediated events 0.5248705233926514 0.2895345866659529 0.7721723163821106 1.0 1.0 3 P49454 1 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.3397847193263233 0.2861012912553881 0.7748005425951556 1.0 1.0 12 Q12873,P16104,Q13185,P84243 4 +Meiotic recombination 0.3589086647624994 0.285539251153931 0.7752310373861109 1.0 1.0 10 P84243 1 +Nuclear import of rev protein 0.3404860591513814 0.2838822514154729 0.7765006185030485 1.0 1.0 31 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Dap12 interactions 0.4020248203788336 0.2760774000031805 0.7824886185419093 1.0 1.0 6 O00459,P10321,P19174,P62993,P63000 5 +Inla mediated entry of listeria monocytogenes into host cells 0.6950424005218481 0.2718692820461874 0.7857225312722753 1.0 1.0 2 O60716 1 +Deposition of new cenpa containing nucleosomes at the centromere 0.3724241604597586 0.2696476248078217 0.7874313576531002 1.0 1.0 8 Q92674,P16104,Q6IPU0,Q96T23 4 +Cyclin a cdk2 associated events at s phase entry 0.3464687635133945 0.2649311106246182 0.7910625315729067 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Rho gtpases activate ktn1 0.3849762651353263 0.2633277975836025 0.7922979361416898 1.0 1.0 7 Q9NSK0 1 +Sialic acid metabolism 0.3939314207463202 0.2632761915917258 0.7923377089099866 1.0 1.0 5 P10619 1 +Beta catenin independent wnt signaling 0.3350934321158497 0.2629516001307311 0.7925878841245593 1.0 1.0 57 P28070,P28072,Q9UBI6,P49721,P28074,Q9HCE1,P20618,P17252,Q92530,P05771,Q99436 11 +Pyruvate metabolism 0.307343409641763 0.2613036017907896 0.7938583892100852 1.0 1.0 18 P21796 1 +Hedgehog off state 0.3402890558441238 0.2599836488726741 0.7948763863390429 1.0 1.0 53 P28070,P28072,P49721,P20618,Q99436 5 +Transcription of the hiv genome 0.3126626300000134 0.2591703507610298 0.7955038063783961 1.0 1.0 20 Q92804 1 +Formation of senescence associated heterochromatin foci sahf 0.3519116202148968 0.2576889525966891 0.7966469727910037 1.0 1.0 10 P16403,P07305,P10412,P16402,P20700 5 +Dna double strand break response 0.3119921252989031 0.2563576744367761 0.7976746669270993 1.0 1.0 17 Q99496,O96028,P49959,P52292,P16104,Q12888,Q92878,P04637 8 +Pyruvate metabolism and citric acid tca cycle 0.3404543403153737 0.2550637919331436 0.7986738292618187 1.0 1.0 35 Q13423,P21796,P48735 3 +Transcriptional regulation by small rnas 0.3407793429254788 0.2512840501311105 0.8015945057808767 1.0 1.0 36 Q8NFH4,Q9BVL2,O15397,Q9BW27,P84243,Q7Z3B4,P16104,Q8NFH5,Q99567,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 15 +Mitotic telophase cytokinesis 0.3495752998139572 0.248585961917822 0.8036810684631446 1.0 1.0 10 Q9Y6X3,Q8N3U4,Q8WVM7 3 +Ret signaling 0.380599036309452 0.2485131520149635 0.8037373953609868 1.0 1.0 7 P17252 1 +Signaling by mras complex mutants 0.6833007175472876 0.2484123918833627 0.803815346681042 1.0 1.0 2 Q9UQ13 1 +Extracellular matrix organization 0.3325676565915259 0.2481792713210058 0.8039957038199117 1.0 1.0 30 O14936,Q32P28,P17252,O75718,P55081,Q08722,P13674 7 +Nuclear pore complex npc disassembly 0.3323188885907814 0.2468151208599371 0.8050513077044454 1.0 1.0 30 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Hemostasis 0.2925210322753975 0.2394626410100811 0.8107468619933389 1.0 1.0 124 Q9UNN8,P84243,P08195,P30154,P42785,P63218,Q86Y91,Q8NBX0,Q9Y6I9,Q08722,O43707,Q08380,P63104,P17252,P05771,P13861,O00459,P14174,Q96JJ7,Q92667,P46108,Q9UBI6,O15439,Q8N2K0,Q92896,P53985,O43852,Q9BX10,Q8IWA4,P30626,P07602,P45973,Q9H0H5,Q9BX67,Q9NSK0 35 +The phototransduction cascade 0.3835423660424928 0.23353054552152 0.8153494532665448 1.0 1.0 5 P17252 1 +Rhobtb2 gtpase cycle 0.3065541675572363 0.2283027892868349 0.8194108562790632 1.0 1.0 20 P62995,P38159 2 +Tnfr2 non canonical nf kb pathway 0.3402220433903562 0.2259961918468233 0.8212043821819517 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Dectin 1 mediated noncanonical nf kb signaling 0.3402220433903561 0.225996191846823 0.8212043821819519 1.0 1.0 43 P49721,P28070,P28072,P20618 4 +Export of viral ribonucleoproteins from nucleus 0.3252665601170058 0.2181144374607777 0.8273399487381632 1.0 1.0 29 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Met interacts with tns proteins 0.6650358773646352 0.2144158404392299 0.8302227900177781 1.0 1.0 2 Q9NWH9 1 +Regulation of hmox1 expression and activity 0.3374935872299719 0.211394305514283 0.8325795998880372 1.0 1.0 47 P28070,P28072,P49721,P28074,P20618,Q99436 6 +Tcr signaling 0.336719551820573 0.2064879137816457 0.8364098047279855 1.0 1.0 47 P49721,P28070,P28072,P20618 4 +Transcriptional regulation by runx2 0.3324466896093547 0.2051227442688896 0.8374762268799847 1.0 1.0 53 P28070,P28072,P49721,Q96PK6,P20618 5 +Regulation of runx2 expression and activity 0.3361695462868681 0.2014778981510103 0.840324909798605 1.0 1.0 46 P49721,P28070,P28072,P20618 4 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.32775943627056 0.2001169933877795 0.8413890833734008 1.0 1.0 11 Q92973,Q9NQT4,Q13868,Q5RKV6,Q15024 5 +Apoptotic execution phase 0.3233882627543351 0.1990778785054337 0.8422018252718302 1.0 1.0 30 P16403,P07305,Q13464,P10412,P02545,P49354,P16402,P51572,P20700,Q14126,Q16625,P08670 12 +Orc1 removal from chromatin 0.3326121573799944 0.1940305371084704 0.846151971101714 1.0 1.0 51 P49721,P28070,P28072,P20618 4 +Degradation of beta catenin by the destruction complex 0.3342714286014481 0.1932865091893679 0.8467345912184467 1.0 1.0 48 P49721,P28070,P28072,P20618 4 +Interleukin 12 family signaling 0.3208900240905956 0.1861717391810489 0.852310085367117 1.0 1.0 30 Q13126,P52597,P22626 3 +Slc transporter disorders 0.3256684025280685 0.1795456295530336 0.8575092921842284 1.0 1.0 34 Q8NFH4,Q9BVL2,Q9BW27,P08195,Q99567,Q8NFH5,P12270,Q8N1F7,P53985,Q9BTX1,Q12769 11 +Regulation of innate immune responses to cytosolic dna 0.474187424410568 0.1780889865733481 0.8586530912161905 1.0 1.0 3 P19474 1 +Switching of origins to a post replicative state 0.3162040248009238 0.1747204592267858 0.861299290917769 1.0 1.0 61 P28070,P28072,Q96DE5,P49721,P20618 5 +Oncogene induced senescence 0.3668422413594085 0.1741968828993848 0.861710735173169 1.0 1.0 6 Q9HCE1 1 +Interleukin 1 signaling 0.3313801851431314 0.172125738344196 0.8633386784649477 1.0 1.0 46 P49721,P28070,P28072,P20618 4 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.3977631676712433 0.1713078031696995 0.863981745119252 1.0 1.0 4 Q15005,P67812 2 +Incretin synthesis secretion and inactivation 0.3977631676712433 0.1713078031696995 0.863981745119252 1.0 1.0 4 Q15005,P67812 2 +Sumoylation of chromatin organization proteins 0.3259668889503155 0.1685816463685621 0.8661257179997561 1.0 1.0 36 Q12873,Q8NFH4,Q9BVL2,Q9BW27,Q99496,Q7Z3B4,Q99567,Q8NFH5,P45973,P12270,Q8WUM0,P57740,Q8N1F7,Q8IXK0,Q9BTX1,Q12769 16 +Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.3543519618922502 0.1660611333716731 0.86810884048902 1.0 1.0 7 P49748,Q16836 2 +Signaling by egfr 0.3182909788488431 0.166025003194464 0.868137273531798 1.0 1.0 11 Q92783,P42566,O14964 3 +Trafficking of glur2 containing ampa receptors 0.3413139361315418 0.1597561700197565 0.873073151791588 1.0 1.0 8 P17252 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.2932153784685925 0.1518157211304353 0.879332282195959 1.0 1.0 16 Q9GZS3,O75381 2 +Rhob gtpase cycle 0.2959243066582042 0.1516853243612252 0.8794351326889385 1.0 1.0 22 O00459,Q9H0H5,Q96RT1,P41440 4 +Met receptor recycling 0.3510772447834314 0.1513257597424121 0.8797187499295511 1.0 1.0 5 P46108 1 +Dcc mediated attractive signaling 0.4580750407830268 0.1489056595360106 0.8816280753422272 1.0 1.0 3 P60953,Q14185 2 +Synthesis of pips at the er membrane 0.6232876712328665 0.1484302521967115 0.8820032266944826 1.0 1.0 2 Q13614 1 +Rho gtpase cycle 0.3025442358754429 0.1418761260276535 0.8871778522072109 1.0 1.0 149 Q5JTV8,Q15904,Q8N684,P06753,P30519,O14964,P61604,O15173,Q92783,Q13505,Q86UP2,Q8N6H7,Q5T8D3,P51572,Q14739,Q96F07,P78371,Q07065,P51648,P28288,O00459,P50402,O75976,P67936,P34897,Q9Y6M7,P80723,Q86XL3,Q96HY6,Q9UQB8,P41440,P62995,P07910,Q9H0H5,Q96RT1,P38159,P20700,P08670 38 +Platelet adhesion to exposed collagen 0.6157860404435641 0.1383139691659919 0.8899922858233533 1.0 1.0 2 P05556 1 +Synthesis of dna 0.2501226205249228 0.1332428805549476 0.894001299383258 1.0 1.0 83 P28070,P28072,Q96DE5,P41440,P49721,P20618 6 +Activation of kainate receptors upon glutamate binding 0.3405879302658539 0.1284638541287783 0.8977819013952171 1.0 1.0 5 Q9UBI6,P63218 2 +Activated notch1 transmits signal to the nucleus 0.6076320939334519 0.1279127563356369 0.898218015880816 1.0 1.0 2 Q92542 1 +C type lectin receptors clrs 0.3207327765236163 0.1277633214025196 0.898336277399528 1.0 1.0 53 P28070,P28072,P49721,P28074,P20618,P17252,Q99436 7 +Antigen processing ubiquitination proteasome degradation 0.253755111890544 0.126889197433514 0.8990280967272559 1.0 1.0 88 P28070,P28072,P49721,Q9UIQ6,P20618,P55786 6 +Rhobtb gtpase cycle 0.3077631724410555 0.1218320986878563 0.9030319922235486 1.0 1.0 30 P62995,P38159,P08670 3 +Laminin interactions 0.6014350945857669 0.1204180517497124 0.904151992223828 1.0 1.0 2 P05556 1 +Viral messenger rna synthesis 0.3090571429243637 0.1193687625013239 0.9049832082291278 1.0 1.0 31 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q8N1F7,Q9BTX1,Q12769 12 +Keratan sulfate degradation 0.3666978932597105 0.1120656077939742 0.9107713866124574 1.0 1.0 4 P15586,P16278 2 +Acyl chain remodeling of cl 0.4345840130505524 0.111964508938481 0.9108515473441908 1.0 1.0 3 P40939,Q6UWP7 2 +Defective intrinsic pathway for apoptosis 0.2904743440127601 0.1090606966940889 0.91315434837938 1.0 1.0 13 P17655,Q08379,P62258,P02545,P20700 5 +Nephrin family interactions 0.3244041965501255 0.1076061344086968 0.9143081306958136 1.0 1.0 8 O00459,O43707,O14936 3 +Inactivation of cdc42 and rac1 0.431321370309944 0.1073585508999676 0.9145045359900484 1.0 1.0 3 P60953,P63000 2 +Perk regulates gene expression 0.2865797433709382 0.1036562075285923 0.917442180701786 1.0 1.0 14 Q13868,Q92945 2 +Activation of ampk downstream of nmdars 0.327456741756451 0.1024885796117474 0.9183688772653036 1.0 1.0 5 Q13885,Q9BVA1,P54619,Q13509 4 +Mismatch repair 0.3147232953662978 0.1015883211512748 0.9190834498581104 1.0 1.0 9 Q9UQ84 1 +Keratan sulfate keratin metabolism 0.3261664313610177 0.1000958774901979 0.9202682081829964 1.0 1.0 5 P15586,P16278 2 +Fc epsilon receptor fceri signaling 0.3162103928328461 0.0995209264668685 0.9207246734608644 1.0 1.0 53 P28070,P28072,P49721,P28074,P20618,Q99436 6 +Pyrimidine salvage 0.4244698205546422 0.0980979649980266 0.921854503430278 1.0 1.0 3 Q08623,P04183 2 +Erythropoietin activates phospholipase c gamma plcg 0.5779517286366458 0.0951534143760222 0.9241929719651168 1.0 1.0 2 P07948 1 +Signaling by hedgehog 0.3092469618930394 0.0900200594942768 0.9282712743730808 1.0 1.0 58 P28070,P28072,P49721,P20618,Q99436 5 +Intraflagellar transport 0.2934249263984351 0.0867047262413802 0.9309062195711504 1.0 1.0 11 Q13885,Q7Z4L5,P63167,Q13509,P68371,Q9BVA1,Q92973,Q9BW83,Q96FJ2,A0AVF1 10 +Uptake and function of anthrax toxins 0.4153344208809121 0.0866088980203521 0.9309823928835051 1.0 1.0 3 P36507,Q8WUM4 2 +Wnt5a dependent internalization of fzd4 0.3004816185287685 0.0834563735145792 0.9334886652189822 1.0 1.0 10 P17252 1 +Signaling by interleukins 0.2658208280928157 0.0806289206303933 0.9357370657402287 1.0 1.0 108 P28070,P28072,P52597,P22626,P49721,Q13126,P20618,P17252,Q99436,P08670 10 +Apc c mediated degradation of cell cycle proteins 0.3048303627503612 0.0805615162496733 0.9357906722688988 1.0 1.0 60 P28070,P28072,Q96DE5,P49721,P20618,Q96GD4,Q99436 7 +Sumoylation 0.2594892382653819 0.0802423402884021 0.9360445160293802 1.0 1.0 77 Q9UQE7,P04637,P41208,Q9BTX1,P61978,Q8NFH5,Q8WUM0,Q8N3U4,P17844,Q9BVL2,Q99496,Q8IY18,P12270,Q8N1F7,Q8IXK0,Q12769,Q12873,Q8NFH4,Q9BW27,Q92841,Q7Z3B4,Q99567,P45973,Q9UER7,P07910,Q8WVM7,Q53HL2,Q96GD4,P57740 29 +Kinesins 0.2659016393442551 0.0776447362020393 0.9381106554293388 1.0 1.0 18 Q07866,Q13885,Q14807,O95239,Q99661,Q8NI77,P33176,Q86Y91,P52732,Q13509,Q12756,Q9H0H5,P68371,O00139,Q9BVA1,Q9Y496,Q9NSK0 17 +Meiosis 0.2838661678580516 0.077462085344556 0.938255952124898 1.0 1.0 24 P84243,P11802,Q9NYB0,P02545,Q8WVM7,P20700 6 +Reproduction 0.2838661678580516 0.077462085344556 0.938255952124898 1.0 1.0 24 P84243,P11802,Q9NYB0,P02545,Q8WVM7,P20700 6 +Metabolism of folate and pterines 0.318333615487735 0.072860980918921 0.9419167440955304 1.0 1.0 7 P41440 1 +Assembly and cell surface presentation of nmda receptors 0.2863583906903711 0.0670291526114332 0.9465584949554164 1.0 1.0 11 P07196,Q14168,O14936 3 +Dna damage reversal 0.3944535073409409 0.0639203691128257 0.9490336332372372 1.0 1.0 3 Q9C0B1,Q8N9N2 2 +Translation of sars cov 2 structural proteins 0.2652874630046314 0.0620102758686162 0.9505546487919272 1.0 1.0 17 P04843,P04844,P46977,Q10472,Q16706 5 +Transport of the slbp dependant mature mrna 0.2958970013212155 0.0607795688943945 0.9515347618939888 1.0 1.0 31 Q8NFH4,Q9BVL2,Q9BW27,Q7Z3B4,Q99567,Q8NFH5,P12270,Q8WUM0,P57740,Q86V81,Q8N1F7,Q9BTX1,Q12769 13 +Rho gtpases activate iqgaps 0.2916939175931983 0.0597613004473134 0.9523457482290508 1.0 1.0 10 Q13885,P35221,P35222,Q13576,Q13509,P68371,P60953,Q9BVA1,P63000 9 +Cd28 co stimulation 0.3065359477124205 0.0589874101873806 0.95296213586574 1.0 1.0 8 O00459,Q16512,P42345,P60953,P07948,P62993,P63000 7 +Free fatty acids regulate insulin secretion 0.388907014681882 0.0586967542284629 0.9531936446330376 1.0 1.0 3 P29992,O95573 2 +Interleukin 1 family signaling 0.3112337354633045 0.0583535231540103 0.9534670347987528 1.0 1.0 48 P49721,P28070,P28072,P20618 4 +Gap junction assembly 0.3273498694517008 0.0569568993314048 0.9545795287228048 1.0 1.0 4 Q13885,Q9BVA1,Q13509 3 +Transport of connexons to the plasma membrane 0.3273498694517008 0.0569568993314048 0.9545795287228048 1.0 1.0 4 Q13885,Q9BVA1,Q13509 3 +Signalling to ras 0.3869494290375165 0.0569305278144393 0.9546005360623532 1.0 1.0 3 P11234,P62993 2 +Signaling by erbb4 0.311887655127365 0.0554694710065471 0.9557644510984716 1.0 1.0 6 P16949,Q92542,P61201,Q96J02,P62993 5 +Mapk family signaling cascades 0.2511663735955176 0.0544888545403184 0.9565456881870618 1.0 1.0 93 P28070,O60725,P28072,P49721,P20618,P49354,P28074,P17252,Q99956,Q99436 10 +Synthesis secretion and deacylation of ghrelin 0.3785385967694165 0.0497896821083033 0.9602899889711968 1.0 1.0 3 Q15005 1 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.3785385967694165 0.0497896821083033 0.9602899889711968 1.0 1.0 3 Q15005 1 +Rmts methylate histone arginines 0.2640174041581208 0.0473676552053332 0.9622202074786425 1.0 1.0 20 Q92922,P62805,Q86U86,Q92925,Q99873,P11802,P16104,Q8TAQ2,Q9BQA1,Q969G3,O14497,Q96GM5 12 +Clec7a dectin 1 signaling 0.3076468143643234 0.0394814646562872 0.9685065310553592 1.0 1.0 48 P28070,P28072,P49721,P28074,P20618,Q99436 6 +Translocation of slc2a4 glut4 to the plasma membrane 0.2972486330392781 0.0373011631696023 0.970244878064532 1.0 1.0 35 Q9Y3B8 1 +Dissolution of fibrin clot 0.4804305283757235 0.0355904341261344 0.9716089359524216 1.0 1.0 2 P07355 1 +Signaling by fgfr4 in disease 0.4791258969341015 0.0351842875007641 0.9719327912321412 1.0 1.0 2 P19174 1 +Signaling by ntrk3 trkc 0.4791258969341015 0.0351842875007641 0.9719327912321412 1.0 1.0 2 P19174 1 +Small interfering rna sirna biogenesis 0.3520391517128864 0.0317192620387687 0.974695933729372 1.0 1.0 3 O75569,Q15631 2 +Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.4556425309849813 0.029109383675759 0.9767773518794788 1.0 1.0 2 P12814 1 +Atf6 atf6 alpha activates chaperones 0.442596216568809 0.0266166160094586 0.9787655202956668 1.0 1.0 2 P14625 1 +Atf6 atf6 alpha activates chaperone genes 0.442596216568809 0.0266166160094586 0.9787655202956668 1.0 1.0 2 P14625 1 +Sumoylation of dna damage response and repair proteins 0.3043161017361217 0.0256101013442351 0.9795683290060848 1.0 1.0 45 Q9UQE7,Q9BTX1,P41208,Q8NFH5,Q8WUM0,Q8N3U4,Q9BVL2,Q99496,Q8IY18,P12270,Q8N1F7,Q8IXK0,Q12769,Q8NFH4,Q9BW27,Q7Z3B4,Q99567,Q8WVM7,P57740 19 +Ras activation upon ca2 influx through nmda receptor 0.2910087895569399 0.0240939827567833 0.9807776429952348 1.0 1.0 6 P07196,Q14168 2 +Unblocking of nmda receptors glutamate binding and activation 0.2910087895569399 0.0240939827567833 0.9807776429952348 1.0 1.0 6 P07196,Q14168 2 +Long term potentiation 0.2910087895569399 0.0240939827567833 0.9807776429952348 1.0 1.0 6 P07196,Q14168 2 +Diseases associated with o glycosylation of proteins 0.4191128506196946 0.0233724176057981 0.981353206556164 1.0 1.0 2 Q14118 1 +Adenylate cyclase inhibitory pathway 0.4171559034572648 0.0231624824603671 0.9815206652321244 1.0 1.0 2 P04899 1 +P38mapk events 0.3868232224396543 0.0208055701381364 0.9834007543741324 1.0 1.0 2 P11234 1 +Ngf stimulated transcription 0.38421395955642 0.0206676457702692 0.9835107784396276 1.0 1.0 2 Q14839 1 +Nuclear signaling by erbb4 0.326264274061993 0.0197234389250213 0.984263992857028 1.0 1.0 3 P16949,Q92542 2 +Plasma lipoprotein remodeling 0.3483365949119327 0.0194527872440793 0.9844799002287744 1.0 1.0 2 Q9BU23 1 +Regulation of tp53 activity through phosphorylation 0.2705468756888499 0.01816564567215 0.985506708894064 1.0 1.0 25 Q9UQ84,Q92804 2 +Cytosolic iron sulfur cluster assembly 0.2849349599426195 0.0163431401433962 0.9869606412720692 1.0 1.0 6 Q9Y5Y2 1 +Neuronal system 0.3000682066413679 0.0141865179512356 0.988681176022406 1.0 1.0 55 Q9UBI6,O14936,Q14168,P21964,P41440,P52292,O95197,P63218,P53680,Q96HC4,P17252,P49593,P10586,P07196,P05771,Q14012,P13861 17 +Cdc6 association with the orc origin complex 0.3047308319738984 0.013057495804296 0.9895819217397712 1.0 1.0 3 Q9Y619,Q9UBD5 2 +Activation of anterior hox genes in hindbrain development during early embryogenesis 0.2534381139489212 0.0099379555469712 0.992070789222063 1.0 1.0 14 P62487,Q92600,P62805,O75928,P84243,O75530,O15514,P16104,P61964,P30876,Q15022,P24928,Q9UBL3 13 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.2687569815183868 0.0069850955799759 0.9944267454023396 1.0 1.0 10 Q15024,Q5RKV6,Q9NQT4,Q13868 4 +Signaling by scf kit 0.2809848046533868 0.001712159624445 0.9986338949374792 1.0 1.0 8 P17252 1 +Thrombin signalling through proteinase activated receptors pars 0.2713678738292972 0.001158307215277 0.9990758047629256 1.0 1.0 6 Q9UBI6,P63218 2 +Rhoc gtpase cycle 0.2780111783707211 0.0001394596030308 0.9998887273362468 1.0 1.0 30 P41440,Q8TAA9,Q9H0H5,Q96RT1,Q5T8D3,P42167,Q14739,P28288 8 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dd22e283d50a8960732ecc5d85b4fa0d3567367f --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell cycle genes", "Foxo mediated transcription of cell death genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates bcl2l11 bim transcription", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATR", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDK", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRD1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "CAB39", "CABIN1", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKAL1", "CDS2", "CENPF", "CENPI", "CENPP", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "COG4", "COG6", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFNB1", "EFTUD2", "EHD1", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF2", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FNTB", "FOXK1", "FOXO3", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP2", "GTPBP3", "GUSB", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAM3", "JUP", "KARS", "KAT7", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LYN", "LYPLA1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "METAP1", "METTL1", "MFAP1", "MFN1", "MFN2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MIPEP", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFCD", "NELFE", "NF1", "NFKB2", "NGEF", "NHLRC2", "NHP2", "NIP7", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOG", "RHOT1", "RHOT2", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMDT1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX17", "STX18", "STX3", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM30A", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOLLIP", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT61A", "TRRAP", "TSFM", "TSG101", "TSN", "TSPO", "TSR1", "TST", "TSTA3", "TTC21B", "TTC26", "TTC37", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WBP11", "WDCP", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WNK1", "WTAP", "XAB2", "XIAP", "XPC", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AATF", "ABCB1", "ABCC4", "ABCD3", "ABHD10", "ABHD12", "ACADVL", "ACAT2", "ACBD5", "ACOX1", "ACOX3", "ACP6", "ACSL3", "ACSL6", "ACTN1", "ACTN4", "ADA", "AFG3L2", "AHCYL1", "AKAP1", "ALDH1B1", "ALDH3A2", "ALG11", "ALYREF", "ANAPC16", "ANKLE2", "ANXA1", "ANXA2", "ANXA6", "AP2S1", "ARFGAP2", "ARHGAP1", "ARID1A", "ASCC1", "ASH2L", "ATP13A1", "ATP2A2", "ATP5B", "ATP5F1", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7B", "ATRX", "AURKB", "BAG6", "BAIAP2", "BASP1", "BCAP31", "BCAS2", "CALU", "CAMK1", "CAPN2", "CASK", "CBFB", "CBX3", "CBX5", "CCT2", "CD2BP2", "CD47", "CDC42", "CDCA8", "CDK4", "CENPF", "CENPI", "CENPP", "CERS2", "CETN2", "CHCHD3", "CHD3", "CHD4", "CKAP4", "CNOT9", "COMT", "COPS2", "COX2", "CPD", "CPSF7", "CRK", "CRTAP", "CTNNA1", "CTNNB1", "CTNND1", "CTSA", "CWC15", "CYB5B", "CYFIP2", "CYP51A1", "DAG1", "DAXX", "DCTN2", "DCTN3", "DDRGK1", "DDX17", "DDX5", "DEGS1", "DHCR24", "DIABLO", "DNAJC3", "DOCK1", "DOHH", "DSG2", "DUSP9", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "EED", "ELAVL1", "EMD", "EPHX1", "EPHX2", "EPS15", "ERBIN", "ERLIN1", "ETFDH", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC2", "EXOSC5", "EXOSC6", "EXOSC7", "FECH", "FGFR1OP", "FIP1L1", "FKBP14", "FNTA", "FOXK1", "FTO", "FUCA2", "FUS", "GALNT1", "GET4", "GLB1", "GLCE", "GLG1", "GNA11", "GNA13", "GNAI2", "GNG12", "GNG5", "GNS", "GOLGA2", "GOLGA5", "GOLIM4", "GOSR1", "GRB2", "GTPBP2", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HADH", "HADHA", "HAUS4", "HAUS6", "HBS1L", "HDGF", "HGS", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-C", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPR", "HNRNPUL1", "HS2ST1", "HSP90B1", "HSPD1", "HSPE1", "ICMT", "IDH1", "IDH2", "IFT27", "IMMT", "IPO8", "IQGAP2", "ITCH", "ITGB1", "JAM3", "KDM1B", "KDSR", "KHDRBS3", "KHSRP", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC4", "KMT2A", "KPNA2", "KTN1", "LBR", "LCLAT1", "LGALS3BP", "LMF2", "LMNA", "LMNB1", "LNPEP", "LRRC8C", "LSM6", "LTA4H", "LYN", "MAN2A1", "MAP2K2", "MAU2", "MFAP1", "MFN1", "MICU1", "MICU2", "MIF", "MOV10", "MPP2", "MRE11", "MSH3", "MTAP", "MTMR2", "MTOR", "MTX1", "MTX2", "NAGLU", "NAMPT", "NCSTN", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB9", "NEFL", "NNT", "NPC1", "NPEPPS", "NSD2", "NT5C3B", "NUBP2", "NUCB1", "NUP107", "NUP133", "NUP160", "NUP35", "NUP37", "NUP54", "NUP58", "NUP85", "NUP88", "NUP93", "OCLN", "OPTN", "ORC3", "OSBPL3", "P3H1", "P4HA1", "PABPN1", "PAPSS1", "PARN", "PBRM1", "PDCD6IP", "PDLIM5", "PECR", "PELP1", "PEX14", "PEX19", "PEX3", "PGRMC2", "PHC2", "PIAS2", "PIK3R2", "PITRM1", "PKN1", "PLA2G15", "PLCG1", "PLD3", "PLK1", "PMPCA", "PMVK", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POMGNT2", "PON2", "PPM1F", "PPOX", "PPP1R12A", "PPP2R1B", "PPP3CA", "PRCC", "PRCP", "PRELID1", "PRKAG1", "PRKAR2A", "PRKCA", "PRKCB", "PRKRA", "PRMT1", "PROCR", "PSAP", "PSMA3", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMF1", "PTGR2", "PTPRF", "PUDP", "PXMP2", "RAC1", "RACGAP1", "RAD50", "RALB", "RBM14", "RBM17", "RBM22", "RBM5", "RBM8A", "RBMX", "RCN1", "RETSAT", "REXO2", "RNF2", "ROCK1", "RPN1", "RPN2", "RSF1", "RTN3", "RTN4", "SARNP", "SCARB1", "SCCPDH", "SEC11A", "SET", "SFPQ", "SGPL1", "SGTA", 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0000000000000000000000000000000000000000..09987b4d1c8061328e464b9f6dab1fb62c37dc3d --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69fbe364708b2a82be27a1bc108a5144dd3ab70cfcdec3cc12afbebc69413327 +size 86888 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b5818bd7ca81608c7966a36eee94cc866bb3bcd8 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial long chain fatty acid betaoxidation 5 14 2.348159039599084 0.0188664636452042 3.349514563106796 13.533980582524272 0.7147062657958151 0.3986109248220331 2.228276960109081 1.0526483843060723 1.0135677936233438 0.2846338064127241 0.0078149165881974 0.0742352733278267 0.0100519320580488 0.0004788146962384 6.703246650942136e-05 +Endothelin pathways 2 8 2.290513826818685 0.0219915479755119 1.9320388349514563 7.987864077669903 0.7329149217629526 0.3753320686971037 1.368949252800948 0.99139418402927 0.9285569766983348 0.277149256001259 0.0098558308218439 0.0032958763634803 0.0126574737404708 0.0086586519898169 0.0539281835546241 +Acquired partial lipodystrophy barraquersimons syndrome 4 5 2.2249558292946663 0.0260842035326995 1.7402912621359223 4.497572815533981 0.9065154927122356 0.2548673055649036 1.4953091418597944 0.5048251951988992 1.235575791841686 0.2574096858611674 1.0 1.0 0.0653907127050202 0.1571881112173651 5.11944457815466e-06 +Overlap between signal transduction pathways contributing to lmna laminopathies 6 16 2.1762919857343817 0.0295334344273501 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 1.0 1.0 0.3530974878629287 0.0940672040532474 0.0055591316089767 +Vitamin a and carotenoid metabolism 1 5 2.099622794632606 0.0357620359674086 1.0606796116504855 4.106796116504855 0.9332890102257668 0.3070288768360753 0.8805930946368925 1.0255249317378814 1.0615219291263185 0.2652373693874932 0.0098558308218439 0.083126337411673 0.0126574737404708 0.0688460117016781 0.0539281835546241 +Pregnane x receptor pathway 2 5 2.090380890819403 0.0365835980703854 1.1893203883495145 4.766990291262136 0.5016334176412254 0.4430864332327935 1.2160266844733736 0.6855496483071739 1.011470017110033 0.3166911340775686 0.0059914484737676 1.0 0.0077184558590264 0.0435926191526008 0.0277461310389573 +Mitochondrial complex iii assembly 5 11 2.085811568558371 0.0369956950913572 3.3106796116504853 9.259708737864075 1.0287385637679851 0.2644162586394033 1.7668969355473032 1.3138647920792297 1.192785152283574 0.2813694304742245 0.1193935721196182 1.0 0.1349531130589082 0.000366006536683 4.367834065541858e-05 +Mrna processing 27 98 2.067453388548489 0.0386914519875725 33.91990291262136 101.1019417475728 -0.5295625237311715 0.5689787072622147 12.879798737734788 4.3055953792039245 1.187736408487459 0.3637876503354037 1.0 1.0 1.0 0.0001973595338559 2.307911670618088e-08 +Statin inhibition of cholesterol production 4 5 2.0505325526615845 0.0403124905327636 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.1118923683980767 1.0 0.1265462710440741 0.2897526236095206 0.003721367796782 +Influence of laminopathies on wnt signaling 5 11 1.996565666715317 0.0458723856399214 2.929611650485437 10.199029126213592 1.172665957836072 0.274405530989148 1.5096443497648335 1.3031697834850824 0.8784257604250459 0.2713478851839423 1.0 1.0 0.2518545844225215 0.1627514901813832 0.0027845492980534 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f0b54433b541bf3ebd8060a6415d7f612272b5a6 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 594, + "title": "Average number of proteins per term", + "value": 10.466329966329967 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3dd28e1f855b1fa38fa94816517ef73bde7fa9de --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c7ce0c4af356350c9186338a7b5506f4cca9d903 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,140 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial long chain fatty acid betaoxidation 0.7003208892513707 2.348159039599084 0.0188664636452042 0.9999877959581378 0.6236392789864199 14 P42126,Q9BY49,P23786,Q16836,O43772 5 +Endothelin pathways 0.8047466989206331 2.290513826818685 0.0219915479755119 0.9999981655361496 0.6236392789864199 8 P00403,P42892 2 +Acquired partial lipodystrophy barraquersimons syndrome 0.8775710088148863 2.2249558292946663 0.0260842035326995 0.9999998480441205 0.6236392789864199 5 P02545,O60725,P49354,Q03252 4 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.6398969645951363 2.1762919857343817 0.0295334344273501 0.9999999815301588 0.6236392789864199 16 O60725,O75844,P50402,P02545,P49354,P55209 6 +Vitamin a and carotenoid metabolism 0.8465234745150451 2.099622794632606 0.0357620359674086 0.9999999995968836 0.6236392789864199 5 O94788 1 +Pregnane x receptor pathway 0.8442506197076971 2.090380890819403 0.0365835980703854 0.9999999997570386 0.6236392789864199 5 O15439,P08183 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9228044565504157 2.0899899695373554 0.0366187007446545 0.9999999997622404 0.6236392789864199 4 P07099 1 +Mitochondrial complex iii assembly 0.6989551478637201 2.085811568558371 0.0369956950913572 0.9999999998115624 0.6236392789864199 11 Q5U5X0,Q6DKK2,P22695,Q9UDW1,O14949 5 +Mrna processing 0.4088562450092465 2.067453388548489 0.0386914519875725 0.9999999999338536 0.6236392789864199 98 P84103,P23246,Q13242,Q15233,Q9UHI6,P55795,P61978,P08621,P67809,Q99729,Q86U42,Q07955,P52756,O95400,P22626,P09012,P31943,O75494,O43390,P35637,Q96I25,Q16629,P62995,P07910,Q9UKA9,P38159,P09651 27 +Statin inhibition of cholesterol production 0.8344760039177224 2.0505325526615845 0.0403124905327636 0.9999999999757267 0.6236392789864199 5 P37268,P35610,Q14534,Q8WTV0 4 +Influence of laminopathies on wnt signaling 0.6813892030796436 1.996565666715317 0.0458723856399214 0.9999999999992304 0.6487665969074607 11 O60725,O75844,P50402,P02545,P49354 5 +Ketogenesis and ketolysis 0.8029022422943444 1.9298079754873896 0.0536306349316837 0.999999999999994 0.6560016353503835 6 P53985,O43772,P23786 3 +Fatty acid betaoxidation 0.5708781941386433 1.907275676867531 0.0564848982004706 0.999999999999999 0.6560016353503835 21 P42126,Q9UKU0,P23786,Q16836,P33121,O43772 6 +Sphingolipid metabolism integrated pathway 0.6924579911833769 1.8585614644713868 0.063089323556444 1.0 0.6560016353503835 9 Q06136,O15121 2 +Sphingolipid metabolism overview 0.6924579911833769 1.8585614644713868 0.063089323556444 1.0 0.6560016353503835 9 Q06136,O15121 2 +Familial partial lipodystrophy fpld 0.7323653432340742 1.7873948435237257 0.0738736944583098 1.0 0.6560016353503835 7 O60725,O75844,P02545,P49354,Q03252 5 +Allograft rejection 0.6769623285112513 1.7832695412403758 0.0745424370743665 1.0 0.6560016353503835 9 Q9BY49,P08183 2 +Sphingolipid metabolism in senescence 0.5936012197583053 1.7554659088165694 0.079179646987918 1.0 0.6560016353503835 14 Q96G23,Q06136,O15121,P17252,P05771 5 +Genes related to primary cilium development based on crispr 0.6516510973528333 1.659138232362496 0.097087940726968 1.0 0.676117239080416 9 Q10713 1 +Omega3 omega6 fatty acid synthesis 0.7328793254399256 1.634707403003374 0.1021103998552646 1.0 0.676117239080416 6 Q15067,O15254 2 +Melatonin metabolism and effects 0.8037640999788264 1.6277389498935733 0.1035802504315115 1.0 0.676117239080416 4 P42892 1 +Tryptophan metabolism 0.5587017042134941 1.6194057048992292 0.105360000182894 1.0 0.676122151482844 15 P35610,Q15392,Q16836,O94788 4 +Proximal tubule transport 0.6051102936862947 1.599731216411441 0.1096582236217114 1.0 0.677424007972915 11 P08195,O15439,P08183,P36543 4 +Constitutive androstane receptor pathway 0.7175980984157311 1.5620999850864046 0.1182644364149521 1.0 0.6777424675652055 5 P08183 1 +Riboflavin and coq disorders 0.7828764450169862 1.544924400341226 0.1223645506576938 1.0 0.6777424675652055 4 Q16134,Q8NI60 2 +Ccl18 signaling pathway 0.6102435949284806 1.5360552791847462 0.1245248231887683 1.0 0.6777424675652055 10 P00403 1 +Striated muscle contraction pathway 0.7104146261834889 1.5314573203152244 0.1256564068550498 1.0 0.6777424675652055 5 O43707,P67936,P08670,P06753 4 +Progeriaassociated lipodystrophy 0.6050511440275606 1.5093366734013067 0.13121276728956 1.0 0.6777424675652055 10 O60725,O75844,P02545,P49354,Q03252 5 +Metabolism of spingolipids in er and golgi apparatus 0.7676473089373166 1.4843091929006251 0.1377269126097711 1.0 0.687477194035328 4 Q06136,O95470 2 +Mecp2 and associated rett syndrome 0.50995766986601 1.3914320578193848 0.1640944490552582 1.0 0.735220760861711 16 P52597,P35637,P67809 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.5467954802894788 1.3777267396091586 0.1682876723333231 1.0 0.7404657582666216 12 Q32P28,Q96AY3,O75718,O15460,P13674 5 +Gpr143 in melanocytes and retinal pigment epithelium cells 0.839029563786964 1.3540269228320778 0.1757277885032375 1.0 0.7424985974068844 3 P17252 1 +Cholesterol biosynthesis with skeletal dysplasias 0.6687911951639143 1.3529448396228692 0.1760732530529538 1.0 0.7424985974068844 5 Q15392 1 +Cytosine methylation 0.6620154299585651 1.3237693430678172 0.1855796606268975 1.0 0.7655161000859525 5 P48735 1 +Alzheimers disease and mirna effects 0.3364354526881349 1.2821014521709433 0.1998070596296772 1.0 0.7808806989328317 82 P28070,P28072,P49721,O95197,P45880,P20618,P21796,Q99436 8 +Alzheimers disease 0.3419808053163695 1.2820607860051636 0.1998213236326438 1.0 0.7808806989328317 80 P28070,P28072,P49721,O95197,P45880,P20618,P21796,Q99436 8 +Sarscov2 and covid19 pathway 0.8058924054505852 1.2301119217949497 0.2186551962880241 1.0 0.7982581255936555 3 Q8WTV0 1 +Metapathway biotransformation phase i and ii 0.4684691608575222 1.2272684970831131 0.2197216919738993 1.0 0.7982581255936555 21 P07099,Q7LGA3,Q86UY6,Q16850 4 +Amyotrophic lateral sclerosis als 0.5440033816885943 1.1923678956060109 0.233117022865025 1.0 0.7990044265868343 10 P20339,P07197,Q08209,Q9UER7,O96008,P07196,P04637 7 +Tumor suppressor activity of smarcb1 0.483118380236275 1.1641849487379512 0.2443490684818317 1.0 0.7990044265868343 15 Q92925,P84243,P11802,Q8TAQ2,Q92785,Q969G3 6 +Calcium regulation in cardiac cells 0.4701603903385151 1.163552879998952 0.2446052564384988 1.0 0.7990044265868343 29 Q9UBI6,P63104,P63218,P16615,Q9Y3B8,P17252,P08133,P05771,Q14012,P13861 10 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4577308691030596 1.1547990910434391 0.2481727094254151 1.0 0.7990044265868343 21 Q15392,Q15126,P37268,Q9BWD1,Q16850,P33121,Q14534 7 +Sleep regulation 0.6840482956381801 1.1498012350763205 0.2502257464443742 1.0 0.7990044265868343 4 P00813 1 +Myometrial relaxation and contraction pathways 0.4575861974849966 1.1410304774595084 0.2538572403047077 1.0 0.7990044265868343 22 Q9UBI6,P63104,P63218,P16615,Q9Y3B8,P17252,P05771,P13861 8 +Initiation of transcription and translation elongation at the hiv1 ltr 0.6141448669962442 1.1211248983396218 0.2622347017717545 1.0 0.7990044265868343 6 Q9H3P2,Q8IXH7,Q08209 3 +Mevalonate pathway 0.6709138556445999 1.097320410118247 0.2725013518077981 1.0 0.8013158563060994 4 Q9BWD1 1 +Drug induction of bile acid pathway 0.9761904761904756 1.0909496141293684 0.2752950540623333 1.0 0.8016551213530024 2 P08183 1 +Cellular proteostasis 0.6072249205867584 1.087647040371296 0.276750955713831 1.0 0.8019027692391006 5 O15212 1 +Gastric cancer network 1 0.5207281388474787 1.0708836038944447 0.2842217690507929 1.0 0.8039943750512479 10 P84243 1 +Vitamin d receptor pathway 0.5064980422703064 1.070842095346573 0.2842404356241785 1.0 0.8039943750512479 11 Q96KA5,P08183 2 +Mevalonate arm of cholesterol biosynthesis pathway 0.5307369460996505 1.052186165335283 0.2927141455485829 1.0 0.8163014199805552 9 P37268,Q9BWD1,Q15126 3 +Dopamine metabolism 0.7463854691704485 1.0090875170889304 0.3129326640605208 1.0 0.8398260463953421 3 P17252 1 +Ppar signaling pathway 0.4454665006223072 0.989133972157312 0.322597598178183 1.0 0.8413527450788771 16 Q9UKU0,P23786,O15254,O14975,Q15067 5 +Preimplantation embryo 0.5575766140493641 0.9889161338789166 0.3227041760932811 1.0 0.8413527450788771 7 Q99729,Q92945 2 +Common pathways underlying drug addiction 0.5296379926764454 0.9826483175675336 0.3257805552936517 1.0 0.8413527450788771 8 P17252 1 +Nanomaterial induced apoptosis 0.7301580733641085 0.949554629520836 0.3423386012978209 1.0 0.8437405647282684 3 O95831 1 +Sudden infant death syndrome sids susceptibility pathways 0.4341754183533331 0.9275510506872352 0.3536404989078565 1.0 0.8437405647282684 27 P42892,P10809,P67809 3 +Oxidation by cytochrome p450 0.5627601690127726 0.8988518220289718 0.3687315928178298 1.0 0.8598363987097822 6 O43169,Q16850 2 +Histone modifications 0.5091189608424465 0.882440518940696 0.3775386322464373 1.0 0.8632273820152369 8 Q01105,P84243 2 +Heme biosynthesis 0.558214402261777 0.878457633925591 0.3796954193138639 1.0 0.8635063594044091 5 P22830,P50336 2 +Wnt signaling pathway 0.4671295008005969 0.8598690973608097 0.3898612048771426 1.0 0.8720715973837397 11 P17252 1 +Ethanol effects on histone modifications 0.4792955322568517 0.8558893544594385 0.3920589838871855 1.0 0.8722211102209295 10 O94788 1 +Thermogenesis 0.4240321631768597 0.8489433750551629 0.3959128015492172 1.0 0.872924323894688 28 Q9UKU0,P23786,P17252,Q969G3,O43772 5 +Kennedy pathway from sphingolipids 0.6985318107667069 0.8350705999803895 0.4036779589110859 1.0 0.8751266700481206 3 O95470,P48651 2 +Mitochondrial complex i assembly model oxphos system 0.4190168296797295 0.8235749676017942 0.4101811042514502 1.0 0.880015553725513 27 Q8N183,O96000,O43676,Q9Y6M9,P03915,Q96CU9 6 +Male infertility 0.4001311344064156 0.7999847677396876 0.4237196225348489 1.0 0.8860025767830539 19 P08183,P41440 2 +Fatty acid transporters 0.5359066375680637 0.7850009943693157 0.4324529855850922 1.0 0.8860025767830539 5 Q9UKU0 1 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4372147933833599 0.7698547720982918 0.4413860451697791 1.0 0.8860025767830539 12 P10809 1 +Circadian rhythm genes 0.4164242291179578 0.751057379980375 0.4526181239369693 1.0 0.8932065302942186 39 Q15233,Q9BWF3,P00813,Q03164,P54802,P11802,Q9Y2W1,P23246,P43490 9 +Corticotropinreleasing hormone signaling pathway 0.3859413739116606 0.7243452125906167 0.4688538262508941 1.0 0.9012918213366702 18 P42892,P17252 2 +7oxoc and 7betahc pathways 0.4618288606364086 0.7081286788065873 0.4788653515135692 1.0 0.9030032342827308 9 P34913,O15118 2 +Nuclear receptors in lipid metabolism and toxicity 0.8548597521200151 0.693440235094155 0.4880333196787738 1.0 0.9090665518275418 2 P08183 1 +Sphingolipid pathway 0.4573597702516556 0.6863616966594835 0.4924850521178114 1.0 0.9113274796198754 9 Q06136 1 +Familial hyperlipidemia type 3 0.833659491193725 0.6288163310978228 0.5294693071379779 1.0 0.9377177376413351 2 Q8WTV0 1 +Eicosanoid metabolism via cyclooxygenases cox 0.494604943775317 0.6139598515491538 0.539241858018539 1.0 0.9393245268710032 6 Q15067,Q8N8N7 2 +Adipogenesis 0.3937811134358377 0.5967307228436464 0.5506871771128132 1.0 0.9421995730536854 14 P43490,O75844 2 +Eicosanoid metabolism via lipooxygenases lox 0.489826517125187 0.5947722646166702 0.5519957094657955 1.0 0.9421995730536854 6 Q15067,Q8N8N7 2 +Glycosaminoglycan degradation 0.4846066570693588 0.5739728900094055 0.565986146708362 1.0 0.9450295746024184 6 P54802,P15586,P16278 3 +Cholesterol biosynthesis pathway 0.4053830965377139 0.5415481012845457 0.5881298526056442 1.0 0.9450295746024184 11 Q16850,Q14534,Q15126 3 +Spinal cord injury 0.361429224151782 0.5223753351982761 0.6014090256253661 1.0 0.9472800100559032 21 P11802,P17252,P08670,Q9NQC3 4 +Kisspeptinkisspeptin receptor system in the ovary 0.4301995555929204 0.5105237124600372 0.6096846063633801 1.0 0.9472800100559032 8 P17252 1 +Pdgfrbeta pathway 0.4173314527658409 0.4971189281499485 0.6191051875212903 1.0 0.9472800100559032 9 P17252 1 +Ketone bodies synthesis and degradation 0.5974394572629739 0.493606966652905 0.6215837797447654 1.0 0.9472800100559032 3 P35610 1 +Prostaglandin synthesis and regulation 0.4427691819102519 0.481967619932574 0.6298289486451207 1.0 0.9472800100559032 7 O15439,P08133 2 +Proteasome degradation 0.3787452794412788 0.4816218225798539 0.6300746209329482 1.0 0.9472800100559032 42 P49721,P28070,P28072,P20618 4 +Effect of progerin on genes involved in hutchinsongilford progeria syndrome 0.3770173272433578 0.4795885259989749 0.6315200067039355 1.0 0.9472800100559032 13 Q12873,P83916,P84243,Q13185,P45973,P04637 6 +Arachidonate epoxygenase epoxide hydrolase 0.7703848662752648 0.4496245753727098 0.6529811648380823 1.0 0.9577057084291876 2 P34913 1 +Dna damage response 0.3456740075564172 0.4423049777372276 0.6582685293861157 1.0 0.9597693020253634 20 Q9Y3B8 1 +Zinc homeostasis 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 0.9679904693954088 3 Q8TAD4 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.7570123939986892 0.4149149435573837 0.6782041699537908 1.0 0.968954597687376 2 P08195 1 +Mirna regulation of dna damage response 0.336927968874266 0.3767496538484822 0.7063596587160625 1.0 0.9751948366499292 21 Q9Y3B8 1 +Mirnas involved in dna damage response 0.7407045009784723 0.3743215477086267 0.7081651026887599 1.0 0.9751948366499292 2 P16104 1 +Mirna regulation of p53 pathway in prostate cancer 0.7407045009784687 0.3743215477086187 0.7081651026887659 1.0 0.9751948366499292 2 O14681 1 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.383040434572359 0.3468427331878464 0.728709471161419 1.0 0.9776898443411344 9 P31943,P62070,P20339,O14964 4 +Ovarian infertility 0.7279843444226877 0.3440635827889252 0.7307984695075147 1.0 0.9776898443411344 2 P11802 1 +G protein signaling pathways 0.3220511255053538 0.338978446061519 0.734625967451779 1.0 0.980601853182824 18 O43823,Q9UBI6,P63218,P17252,P05771,P13861 6 +Bladder cancer 0.3988945188380212 0.3122634365713039 0.754840325076215 1.0 0.9923993139062278 7 O00459,P11802 2 +Joubert syndrome 0.3280557810187037 0.3092080544004981 0.7571632674015258 1.0 0.9923993139062278 16 Q10713 1 +Erbb signaling pathway 0.3137975744795596 0.2947033028151403 0.7682205398969226 1.0 1.0 18 P05771,P17252 2 +Cohesin complex cornelia de lange syndrome 0.3287494223491298 0.2886973346984522 0.7728130025009898 1.0 1.0 15 Q9Y6X3,Q8N3U4,P53350,Q96GD4 4 +Extracellular vesiclemediated signaling in recipient cells 0.4453559003863809 0.288013166077499 0.7733366604297096 1.0 1.0 4 Q9NWH9 1 +Dna mismatch repair 0.3186846539781635 0.2637463216490234 0.7919753993727552 1.0 1.0 16 P41440 1 +Eicosanoid synthesis 0.6865622961513277 0.2548041066175835 0.798874403322539 1.0 1.0 2 P09960 1 +Folate metabolism 0.3158124806751901 0.2298484901347499 0.818209503594092 1.0 1.0 15 Q8WTV0 1 +Orexin receptor pathway 0.3048641430994237 0.2199556120501734 0.8259057245413712 1.0 1.0 20 O00459,Q9H4L5,P50336,Q8TDW0,P17252,P31350 6 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0.1485463686737682 0.8819115949233913 1.0 1.0 15 P17252 1 +Pathways affected in adenoid cystic carcinoma 0.2937515295344555 0.1395574275517968 0.8890096792422617 1.0 1.0 15 P10412,P46100,Q96RT1,Q9UBU8,Q99417,Q969G3 6 +Ferroptosis 0.2977362997171137 0.1362905176170666 0.8915916197837177 1.0 1.0 24 Q9UKU0,P37268,Q15043,P16435,P45880,P33121 6 +Ectoderm differentiation 0.2804183521555753 0.1353449849295566 0.8923391194353174 1.0 1.0 18 P17480,O15439,Q9HBH5 3 +Praderwilli and angelman syndrome 0.3406604445431547 0.1286154930820197 0.8976619064270126 1.0 1.0 5 P11802 1 +Nephrotic syndrome 0.2955827473550503 0.1195929827367258 0.9048055787916434 1.0 1.0 12 O43707,O75844,Q9BT22,P02545,Q14108 5 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.5988258317025312 0.1173673662255872 0.9065689432863197 1.0 1.0 2 P09601 1 +Gdnfret signaling axis 0.4313213703099492 0.1073585508999746 0.9145045359900428 1.0 1.0 3 P35222,Q9BW83 2 +Development of ureteric collection system 0.4313213703099375 0.1073585508999587 0.9145045359900554 1.0 1.0 3 P35222,P05556 2 +Gpr40 pathway 0.5779517286366456 0.0951534143760219 0.924192971965117 1.0 1.0 2 P29992 1 +Neuroinflammation and glutamatergic signaling 0.284612596053044 0.0913582929888479 0.9272079004850348 1.0 1.0 23 Q8TDW0,P17252 2 +Kit receptor signaling pathway 0.2706054309424966 0.0830439362975606 0.933816604128378 1.0 1.0 19 P05771,P17252 2 +Physicochemical features and toxicityassociated pathways 0.2716273333463098 0.0723304966934835 0.9423388953984008 1.0 1.0 16 P07197,P35080,Q14012 3 +Hepatitis b infection 0.2739639093505159 0.0721660548383939 0.9424697590276356 1.0 1.0 21 P05771,P17252 2 +Ciliopathies 0.275028380151776 0.0671299297894027 0.9464782671034886 1.0 1.0 14 O43924,Q9UBB4,P49454,Q10713 4 +Arrhythmogenic right ventricular cardiomyopathy 0.2765576071104292 0.066583375314338 0.9469133809493696 1.0 1.0 13 Q14118,O43707,P35221,P50402,P35222,P02545,P16615,Q14126 8 +Ciliary landscape 0.2550079886964344 0.06029226751193 0.9519228603754571 1.0 1.0 97 O95400,P16278,Q9HDC9,O43805,P10619,P84243,P07197,Q96PK6,Q13868,Q9Y4W6,O95721,P55081,Q15024,Q9UPT5,P08670,O15173 16 +Wnt signaling 0.2690108961546444 0.0555403700858837 0.9557079688898384 1.0 1.0 15 P17252 1 +Notch signaling 0.3699836867862996 0.0432469299647465 0.9655046953578736 1.0 1.0 3 Q92542,P56545 2 +Fas ligand pathway and stress induction of heat shock proteins 0.264042170811154 0.0362071866755351 0.9711171556100342 1.0 1.0 14 P02545,Q03252 2 +Angiogenesis 0.481735159817337 0.0360044654418762 0.971278798356674 1.0 1.0 2 P19174 1 +Unfolded protein response 0.3487765089722697 0.0299210451496101 0.9761300217602032 1.0 1.0 3 Q9Y3I0,P04637 2 +Interactions between loxl4 and oxidative stress pathway 0.2924281984334258 0.0253109772290758 0.9798069181745022 1.0 1.0 4 Q9BQ95,Q96EB6,Q8TAG9 3 +Ptf1a related regulatory pathway 0.4044357469014957 0.0219849557052251 0.9824599562466688 1.0 1.0 2 P35222 1 +22q112 copy number variation syndrome 0.2853832059219151 0.0189301305518784 0.984896843139708 1.0 1.0 31 Q9BW71,P21964,Q9NQ50,P45973,O94788,Q92973,O95721,Q9NQC3 8 +Small cell lung cancer 0.2883712217689211 0.0167654775051182 0.986623710984422 1.0 1.0 8 O00459,P11802 2 +Endoplasmic reticulum stress response in coronavirus infection 0.2786683066930002 0.0089711073292696 0.9928421879798324 1.0 1.0 6 O14974 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2ce0c5eb1b8bc9aa744dea11c8108926f7dfc0a2 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APC", "APEX1", "APMAP", "APPL1", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATG9A", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AURKB", "BAG3", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BLVRA", "BLVRB", "BPTF", "BRD1", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "C1QBP", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHMP6", "CHORDC1", "CHRAC1", "CHTF18", "CIP2A", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ8A", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAG1", "DARS", "DAXX", "DBNL", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJC3", "DNAJC7", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFNB1", "EFTUD2", "EHD1", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXO3", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E2", "GTF2I", "GTPBP2", "GTPBP4", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "IMP3", "IMPAD1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3BP", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LPP", "LRP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSS", "LTA4H", "LYN", "LYRM7", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MMADHC", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NARS2", "NAT10", "NBN", "NCAPG", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NFKB2", "NGEF", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NR3C1", "NSDHL", "NSF", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OSBPL3", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKB", "PI4K2A", "PIAS2", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPT1", "PODXL", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPMS", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARS", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC13", "SEC23A", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STX4", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TALDO1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCF20", "TCP1", "TDP2", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TMED10", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TTC19", "TTC21B", "TTC26", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UPF1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS18", "VPS33A", "VPS4A", "WARS", "WDCP", "WDHD1", "WDR1", "WDR5", "WNK1", "XAB2", "XIAP", "XPC", "XPNPEP3", "XPO1", "XPO5", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ABCC4", "ACAT2", "ACOX1", "ACOX3", "ACSL1", "ACSL6", "ACTN4", "ADA", "AFG3L2", "AIFM1", "AKAP8", "ALDH1A2", "ALG1", "ANXA6", "AP2S1", "APMAP", "ARFGAP2", "ATP2A2", "ATP6V1E1", "ATRX", "ATXN10", "AURKB", "CAMK1", "CBX1", "CBX3", "CBX5", "CD2BP2", "CDK4", "CENPF", "CERS2", "CHD3", "CLPTM1L", "COMT", "COQ8A", "COX2", "CPT2", "CRK", "CRTAP", "CTBP2", "CTNNA1", "CTNNB1", "CTSA", "CYB5B", "CYP51A1", "DAG1", "DAXX", "DDX20", "DEGS1", "DHCR24", "DPF2", "DSG2", "ECE1", "ECH1", "ECI1", "ECSIT", "EI24", "EMD", "EPHX1", "EPHX2", "ERBIN", "ETFDH", "EXOC6", "EXOC7", "EXOSC2", "EXOSC7", "FDFT1", "FECH", "FKBP10", "FNTA", "FOXRED1", "FUS", "GLB1", "GNA11", "GNG12", "GNG5", "GNS", "GRB2", "H2AFX", "H3-3A*", "HADH", "HDGF", "HGS", "HIRIP3", "HIST1H1E", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPR", "HS2ST1", "HSPD1", "ICMT", "IDH2", "IFT27", "ITGB1", "ITM2C", "KDSR", "KHSRP", "KMT2A", "LMNA", "LMNB2", "LRRC8C", "LTA4H", "LYRM7", "MAP2K1", "MAP2K2", "MAPK1", "MAU2", "MFAP1", "MORF4L1", "MRPL40", "MYCBP", "NAA40", "NAGLU", "NAMPT", "NAP1L1", "NCSTN", "ND5", "NDUFA13", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB9", "NEFL", "NEFM", "NELFA", "NELFCD", "NONO", "NPC1", "OSBPL3", "P3H1", "P4HA1", "P4HA2", "PABPN1", "PDE6D", "PECR", "PFDN6", "PFN2", "PGRMC2", "PIK3R2", "PLCG1", "PLK1", "PMPCA", "PMVK", "POR", "PPOX", "PPP1R12A", "PPP2R1B", "PPP3CA", "PPT2", "PRCC", "PRKAR2A", "PRKCA", "PRKCB", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PSMB7", "PTBP2", "PTDSS1", "PTGR2", "RAB5A", "RACGAP1", "RBM14", "RBM17", "RBM4", "RBM5", "RBMX", "RDH14", "REXO2", "RRAS2", "RRM2", "RTCB", "RTN3", "RTN4", "SCARB1", "SCARB2", "SET", "SFPQ", "SGPL1", "SIRT1", "SLC16A1", "SLC19A1", "SLC25A20", "SLC27A2", "SLC30A5", "SLC39A14", "SLC3A2", "SLC4A7", "SLTM", "SMARCC2", "SMARCD2", "SMARCE1", "SNAP29", "SNRNP70", "SNRPA", "SOAT1", "SQLE", "SRSF1", "SRSF10", "SRSF3", "SRSF7", "SRSF9", "SSNA1", "STAG2", "STAM", "THRAP3", "TNPO1", "TOMM40", "TP53", "TPM3", "TPM4", "TRA2B", "TTC19", "UBTF", "UQCR10", "UQCRC2", "UQCRQ", "VDAC1", "VDAC2", "VIM", "YBX1", "YWHAZ", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..97a738dbb09605e620de445bf1930eba7412da62 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "nuclear_membrane", "1": "chromatin", "2": "nucleolus_fc_dfc"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..546447a76305233ac4de4c48960c6a8b71694ac6 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c04909ad70dd42b77d2685475e37bd9b4972cf4dce4b4df34322df23d41417ef +size 148716 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2d9c194d987faa8bee9ef108e522afc3816bcceb --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0feb063abde7374e177ed69604ca95de83522d0c32f8616121c65a8fbe47143 +size 145581 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..bbb1c3edd19ea36ee2401457c64ed7a0f459cc5d --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6748e1fdb7826bc32f1fc7979a0ab0f4a952ce0bbf12d04f42519da607e15ab +size 147515 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..60c958004a3d7427cba0214d0520d93cc31359ea --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4bd8ba6e78ab0aaafc71acf16d745c6efe73dbdb72bedaeb773cad0155a7fc2 +size 68167 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..904c0a04e672bd6783589490783fef0082315252 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +mitochondria 1 10 2.2484049608861847 0.0245503791453223 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0051636995807174 0.0607401038440192 0.0066572828402184 0.0379575415698398 0.1289341732663725 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..76f7d2ab6b4baa8c77eb72f6b308a3c3caacb68c --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 91.58823529411765 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..52b8a48145b983a1c603a1fa8e2acbad40362f06 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..110f843c1e0e9937c9bbc6242194a1589c7dfc34 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mitochondria 0.7533538118858137 2.2484049608861847 0.0245503791453223 0.3446363454797345 0.4173564454704794 10 P21796 1 +nuclear_membrane 0.4048532201079703 0.6823922973605554 0.4949909250117112 0.9999909617135464 1.0 33 Q5JTV8,P61970,P52292,Q8NFH5,P12270,P02545,Q92973,P20700 8 +chromatin 0.2846852775723781 0.4711081415509839 0.637563511411825 0.9999999678676462 1.0 91 Q9Y5S9,P23246,P41208,Q15233,Q14103,P83916,Q9NW64,Q8N3U4,P52756,Q9ULX6,Q14004,P09012,Q9BQ61,Q8TAQ2,Q969G3,P31943,Q9BWF3,P49756,P07305,Q96I25,P98175,P07910,Q8WVM7,Q96GD4,Q96T37,P38159 26 +nucleolus_fc_dfc 0.2916002168708528 0.1709136335322319 0.8642916763915667 0.9999999999999982 1.0 19 Q15233,Q9NY12,Q01844,Q96PK6,P17480,Q13428 6 +focal_adhesions 0.2886059418870471 0.0428081476196292 0.9658544690837538 1.0 1.0 5 P18206,Q13177,Q6RW13,Q16512 4 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..952fd688f0db61f8765a8a92c86cc2ff42b76701 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AGTRAP", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT1S1", "ALCAM", "ALDH9A1", "ANAPC16", "ANAPC2", "ANAPC4", "ANXA11", "AP2B1", "AP2S1", "APC", "APPL1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG7", "ATG9A", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1B", "BYSL", "C1orf123", "C8orf33", 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sha256:4dddf348462786b3cb0ea0e237322c4307b3ead734ca8484463ead2163177b8d +size 141214 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a1b02c0aee69d5a6128ec5df74dd9980ae1febad --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5903fe879c74a6105be19ffae2b325d18ccb179931f44caab4c92a54877bc2d4 +size 73570 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d783f4ccd381e134170ea0473158963a5bbd4944 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +calmodulin-related 7 12 2.78452660883127 0.0053605922507529 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 5.213429728271395e-05 0.0063255491406275 8.694316847855437e-05 1.4492280010576038e-06 1.515921045849114e-05 +transmembrane signal receptor 3 7 2.402528920009104 0.0162821470582013 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.1818809531756908 0.0720814043883259 0.2213471409258044 0.1818956974368412 0.6593661810718379 +RNA splicing factor 32 80 2.224028304390377 0.0261465399595937 25.516990291262136 80.2135922330097 -0.4027847736134791 0.5859415472752173 9.732450108601151 5.238766039835511 1.0479507672919537 0.3497485651761058 1.0 1.0 1.0 0.0111927939680839 0.0001193187987068 +transporter 18 61 2.201450058674229 0.0277041785074692 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 0.000447198795434 1.877054437832283e-05 0.0001278957824949 2.421501969109259e-05 3.174131100404598e-06 +metalloprotease 10 27 1.9761452178319463 0.0481383323573121 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 8.676769010067325e-05 0.0021781449325651 0.0001612622666265 0.0018183768983854 0.001050513287845 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c158f5c8f11eeef4a46a2fda46d058512a4a49d2 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 160, + "title": "Average number of proteins per term", + "value": 13.19375 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..56230d0e39206b5f186a0de169e92a68e8699451 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8029107d1cf2413520870ec7451e2bc41dd50aab --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +calmodulin-related 0.8162132763195914 2.78452660883127 0.0053605922507529 0.576838715254412 0.5453862327033123 12 Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q02818,O43852 7 +transmembrane signal receptor 0.8749663224033337 2.402528920009104 0.0162821470582013 0.9276749876835284 0.5453862327033123 7 Q8WUJ1,Q9UMX5,O15173 3 +RNA splicing factor 0.4132469083677818 2.224028304390377 0.0261465399595937 0.9855795816823216 0.5453862327033123 80 O75940,P84103,P62312,Q8IWZ8,Q96PK6,Q08170,Q96PU8,P31942,Q93062,Q13242,P52597,P55795,Q07666,P08621,Q9BWU0,Q9NW64,Q6IQ49,Q07955,O75934,O95400,Q9Y4C8,Q9P2K5,P09012,Q9H9Y2,O75525,P31943,Q12972,Q9BWF3,O75494,Q14331,Q96I25,Q16629 32 +transporter 0.5365079050855094 2.201450058674229 0.0277041785074692 0.9888378695092132 0.5453862327033123 61 Q8NFH4,Q99595,O60830,P62072,Q567V2,Q99808,Q9NR77,Q92973,P41440,P52292,Q9Y584,Q9H2V7,Q9HD45,Q99805,Q8N1F7,P53985,Q6N075,O43772 18 +metalloprotease 0.5869637242307928 1.9761452178319463 0.0481383323573121 0.9996269096324836 0.567479293744384 27 Q8IYS1,O75844,Q5JRX3,Q9UIQ6,Q9Y4W6,P22695,P42892,Q10713,P55786,P52888 10 +primary active transporter 0.5612494323721133 1.8355166033449517 0.0664291812883943 0.9999832674199424 0.567479293744384 22 Q9NS69,Q8N4H5,Q15758,P12270,O60888,P16615,O75381,P35670,Q96NB2 9 +serine protease 0.5770361160600288 1.803147610495038 0.0713650356449029 0.9999928351842684 0.567479293744384 16 Q9HB40,Q4J6C6,P42785,Q16740 4 +ATP-binding cassette (ABC) transporter 0.7680597632506372 1.7839450884098604 0.0744325883544183 0.9999957802296302 0.567479293744384 6 O15439,P08183 2 +voltage-gated ion channel 0.9351645766043768 1.7120146719515097 0.0868939646510482 0.9999995176146222 0.567479293744384 3 P21796 1 +calcium-binding protein 0.7461552737983435 1.6912421852282606 0.0907905570565641 0.999999756650747 0.567479293744384 6 P50995,P09525,P20073,P08133 4 +secondary carrier transporter 0.5396880397600142 1.652759028832418 0.0983799155505509 0.9999999363538123 0.567479293744384 17 Q9Y666,Q15043,O14975,Q9Y6M7,Q9BQT8,Q6NT16,Q9UBX3 7 +esterase 0.7266220459331556 1.6079752706201305 0.1078405949477447 0.9999999882295436 0.567479293744384 6 Q9NUJ1 1 +protein-binding activity modulator 0.7238645510330729 1.5887827551045828 0.11210944790027 0.9999999945360142 0.567479293744384 5 Q9UNN8 1 +lyase 0.5934056501055209 1.5376423135489274 0.124136095506584 0.9999999993836028 0.567479293744384 11 Q9UHG3 1 +SNARE protein 0.5712664493326636 1.5132370279067642 0.1302194618439265 0.9999999997979078 0.5787531637507846 12 O95249,Q9P2W9,P56962,Q86Y82,O95721 5 +histone 0.588559865430962 1.4241736421049631 0.1543962128837892 0.9999999999977782 0.617584851535157 10 P84243,P07305,P16104,P10412,P16402 5 +heterotrimeric G-protein 0.5867181371660207 1.2628608019395926 0.2066392090676778 1.0 0.6747402745067032 8 Q14344,Q9UBI6,Q8NHH9,P63218,P04899 5 +ATP synthase 0.4560339118211038 1.157012330544099 0.2472673226138679 1.0 0.6999208648943558 20 Q15904,Q9Y487,O75964,P06576,P00846,Q93050,P24539 7 +acyltransferase 0.453449036245699 1.154201868028096 0.2484174169150392 1.0 0.6999208648943558 19 Q8NCC3,P53609,Q9BWD1,P23786 4 +oxygenase 0.587164544186188 1.1252800554207636 0.2604703785617586 1.0 0.6999208648943558 7 P30519,Q16850 2 +kinase 0.4604052015998743 1.0822296778188347 0.2791504843715935 1.0 0.7203883467654025 16 Q9HA64,P22392,P52789 3 +oxidoreductase 0.438329286476426 0.937623364733524 0.3484379997208005 1.0 0.7852123937370152 44 O14949,Q86Y39,P00403,O96000,O15254,Q8N0U8,O43676,Q8N4Q0,O95831,Q16134,O43169,Q9Y6M9,Q15067,P03915 14 +nucleic acid metabolism protein 0.59856396866842 0.812415992722596 0.4165529725549075 1.0 0.8438864986278518 4 Q9NYF8,Q96FV9,Q9Y2W1 3 +microtubule binding motor protein 0.4019458984068053 0.7714554734645142 0.4404370050145338 1.0 0.8444085936518015 17 O75935,Q86Y91,Q13561 3 +protein modifying enzyme 0.3963830533016675 0.7449257670822875 0.4563165971564284 1.0 0.8444085936518015 21 O60725,Q9UMR5,O75718,Q92791 4 +G-protein coupled receptor 0.672252724741356 0.7420378363914537 0.4580644116015204 1.0 0.8444085936518015 3 Q5VW38 1 +major histocompatibility complex protein 0.5535908852944853 0.6427055390238321 0.5204151862084438 1.0 0.9092445854199188 4 P04439,P55899 2 +membrane trafficking regulatory protein 0.3886900658813792 0.6030884393548834 0.5464498567044034 1.0 0.9169298856917704 15 Q8WTV0,Q9P253 2 +glycosyltransferase 0.3619293221634094 0.57263370705705 0.5668927321054751 1.0 0.9169298856917704 18 P04843,P04844,Q9BT22,P46977,Q8NAT1,Q86SF2,Q10472,Q8TCJ2 8 +protease 0.3911754594705539 0.5689166541070564 0.5694127027246685 1.0 0.9169298856917704 39 P28070,P28072,P49721,P28074,P20618,Q99436 6 +G-protein 0.4751796211626466 0.5368671133326383 0.591359408928362 1.0 0.9186165575586206 6 P84085,Q96KC2,P08240,P18085,P40616 5 +methyltransferase 0.4088019981300252 0.5054700052536852 0.6132287605130053 1.0 0.9328568047523826 10 P21964,Q8N6R0 2 +phosphatase 0.3755816503971443 0.4986618382750609 0.6180176331484535 1.0 0.9328568047523826 14 Q9NPH0 1 +kinase modulator 0.4239629721992638 0.4066763045386866 0.6842457461452782 1.0 0.961533595461446 7 Q93052,P13861 2 +RNA metabolism protein 0.2806097982269374 0.3869650938024708 0.6987820498032926 1.0 0.961533595461446 94 Q9BX40,Q5JSZ5,Q71RC2,P23246,Q8WXF1,Q13428,Q15233,Q9NYH9,Q9P2N5,P61978,O60506,Q92804,Q96AE4,Q92945,Q92615,A9UHW6,Q96KR1,Q86V81,Q96I24,Q01844,P78316,O43390,P35637,Q8IY67,Q9Y6M1,Q13601,Q96T37 27 +amino acid transporter 0.4268005269608693 0.3670765633171381 0.7135619086360734 1.0 0.961533595461446 5 P30825,O14925 2 +hydratase 0.4239450283556385 0.3575219154069126 0.7207011227462521 1.0 0.961533595461446 5 Q13011 1 +hydrolase 0.3321210924506454 0.2975532047223396 0.7660441947266923 1.0 0.9964802533030144 25 P34913,P07099,P15586,Q68D91,Q96AB3,O43865,O60502 7 +decarboxylase 0.6983039791258908 0.2786027570889258 0.7805496966063215 1.0 0.9980196013382666 2 P14174 1 +dehydratase 0.6712328767123221 0.2256057473981613 0.821508070317398 1.0 1.0 2 P61457 1 +DNA glycosylase 0.6265492498369046 0.1529932793340264 0.8784035752113999 1.0 1.0 2 P78549 1 +chaperone 0.2944908140478265 0.1115399417613822 0.9111881942430462 1.0 1.0 67 Q5U5X0,Q96JJ7,Q9H7H0,Q8N183,O15260,Q99615,Q9NWM8,Q9Y680,Q9Y2R0,P46379 10 +transferase 0.3033274489881976 0.1103829536301139 0.9121056715442356 1.0 1.0 29 P48651,Q2TAA5,P49903,Q7LGA3,P37268,P43490,Q9NRN7,Q9Y5P6 8 +viral or transposable element protein 0.4308304052317351 0.106676431801 0.9150456805927728 1.0 1.0 3 P07199 1 +tight junction 0.4742335290280394 0.0337297559649291 0.9730926506385676 1.0 1.0 2 Q07157 1 +histone modifying enzyme 0.2545067749640529 0.0108706233504899 0.9913266682845988 1.0 1.0 12 Q92785,Q9H0E3,Q03164 3 +phosphatase modulator 0.2802819210141517 0.010809663446215 0.9913753043933732 1.0 1.0 6 O14974 1 +zinc finger transcription factor 0.2844159958911417 0.008151212644092 0.993496345299132 1.0 1.0 7 Q9H1B7,Q9UGU0 2 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..403bdf912100a737afb22b9510b49d796c4b8eed --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "membrane-bound signaling molecule", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase inhibitor", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALYREF", "ANAPC1", "ANAPC7", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL5B", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATG7", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BAG6", "BAIAP2", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCR", "BDH2", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPHL", "BPNT1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHERP", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA3", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAM3C", "FAM89A", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS2", "GLA", "GLB1", "GLCE", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LENG8", "LETM1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LYAR", "LYPLA1", "LYPLAL1", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MAT2B", "MBLAC2", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIF4GD", "MIPEP", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCOA5", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NENF", "NF1", "NFKB2", "NGEF", "NHP2", "NIP7", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PHKB", "PI4K2A", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A14", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", 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sha256:780c70e0b56b373b4a3035e784a2d56dfa3b93b544a0abab7a70f6efa81cfda9 +size 227853 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..99f258b19f53d1145d3e56d45c59a9dafb724b67 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Calcium-binding protein 8 17 3.2661370183807232 0.0010902548209708 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.000587733874639 0.0204708743585679 0.0009611330378982 1.2098982240396002e-05 0.0003072272517183 +Intracellular calcium-sensing protein 7 14 2.965543003589369 0.0030214909962287 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0001416817577616 0.0102371045657047 0.0002347353167816 8.783345770860822e-06 0.000109129133689 +Calmodulin 7 14 2.965543003589369 0.0030214909962287 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0001416817577616 0.0102371045657047 0.0002347353167816 8.783345770860822e-06 0.000109129133689 +mRNA processing factor 36 75 2.8863484865092706 0.0038974035077952 25.347087378640776 75.25485436893204 -0.2985441958276097 0.5602779604890878 10.316515944124484 3.6776154061944775 1.2913421409729118 0.3651678095317845 0.5909771857241556 1.0 0.2676422850845579 7.963143199961232e-06 4.443762572164574e-09 +SLC25 family of mitochondrial transporters 3 18 2.5891969090779567 0.0096200067660296 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0036602338119252 0.0135379522122687 0.0052800410185589 0.0116952906397438 0.0319540971359957 +Signaling 7 18 2.5527396125970965 0.0106879365586087 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.1698153099549775 0.0667099047189351 0.2072288126229632 0.1629443488297355 0.0633160148044729 +SLC superfamily of solute carriers 18 47 2.356701193828389 0.0184380765513949 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.0186789112560743 0.0566899593979067 0.030764752930157 0.0127614973190033 0.0013321033486234 +mRNA splicing factor 29 60 2.267468857236175 0.0233615992706031 20.18446601941747 60.25 -0.0534479997211008 0.543839505368344 8.174667919166573 3.2318387263906065 1.3503022593676848 0.3639653466937346 0.5021033644449397 1.0 0.1862598674919939 5.522495427233563e-07 1.3553994102061855e-09 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4d288f8563db36212823f67cafad5b042be6520d --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 1987, + "title": "Average number of proteins per term", + "value": 3.1077000503271264 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f27609a04810e3e52e1daacaaf61eef1e4f48e2f --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f51614fd96801c015b7aebc9b06c9450ceece357 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,56 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Calcium-binding protein 0.817380173463763 3.2661370183807232 0.0010902548209708 0.8855386557310903 0.2355545203203195 17 Q8IYU8,Q14257,Q9BPX6,Q15293,P43307,P80303,Q02818,O43852 8 +Intracellular calcium-sensing protein 0.8192755450104956 2.965543003589369 0.0030214909962287 0.9975527516004 0.2355545203203195 14 Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q02818,O43852 7 +Calmodulin 0.8192755450104956 2.965543003589369 0.0030214909962287 0.9975527516004 0.2355545203203195 14 Q8IYU8,Q14257,Q9BPX6,Q15293,P80303,Q02818,O43852 7 +mRNA processing factor 0.5109604271114843 2.8863484865092706 0.0038974035077952 0.9995732324687092 0.2355545203203195 75 P84103,P62312,Q8IWZ8,Q96PK6,O95104,Q96PU8,Q08170,P23246,Q93062,Q8WXF1,Q13242,Q15233,Q07666,P08621,Q96SI9,Q07955,O75934,Q92804,Q9Y4C8,P09012,Q14011,Q96KR1,O75525,Q13595,Q01844,Q9BWF3,O75494,P35637,Q96I25,Q8IY67,O95453,Q16629,P62995,Q96E39,P98179,P38159 36 +SLC25 family of mitochondrial transporters 0.6763767725442996 2.5891969090779567 0.0096200067660296 0.9999999954470496 0.2355545203203195 18 Q9UBX3,O43772,Q70HW3 3 +Signaling 0.6702564712082276 2.5527396125970965 0.0106879365586087 0.9999999994663252 0.2355545203203195 18 Q8WUJ1,Q7Z4V5,O00264,P43490,P51858,Q96PC5,O15173 7 +SLC superfamily of solute carriers 0.6137770224349012 2.3567011938283895 0.0184380765513949 1.0 0.2355545203203195 47 Q9Y666,Q8TAD4,Q99808,Q70HW3,P41440,Q15043,Q9UBX3,O14975,Q8TB61,P30825,Q9Y6M7,Q9H2V7,Q8IXU6,Q9BQT8,Q6NT16,P53985,Q6N075,O43772 18 +mRNA splicing factor 0.5489702805284978 2.267468857236175 0.0233615992706031 1.0 0.2355545203203195 60 P84103,P62312,Q8IWZ8,Q96PK6,Q08170,Q96PU8,P23246,Q93062,Q8WXF1,Q13242,Q15233,P08621,Q07955,O75934,Q92804,P09012,Q14011,O75525,Q13595,Q01844,Q9BWF3,O75494,P35637,Q8IY67,Q16629,P62995,Q96E39,P98179,P38159 29 +ATP-binding cassette transporter family 0.7680597632506372 1.7839450884098604 0.0744325883544183 1.0 0.2833286457092515 6 O15439,P08183 2 +Phosphatase inhibitor 0.7261436528052747 1.759636198581576 0.0784695098464909 1.0 0.2898121116449395 7 P55209,Q99733 2 +Growth factor 0.7357359268301449 1.6468932991355782 0.0995799794682223 1.0 0.3170920179540992 6 Q7Z4V5,Q5JRA6,Q96PC5,P51858 4 +Extracellular structure 0.6479813491322713 1.6410287183337404 0.1007914539444851 1.0 0.3192000570275673 9 Q92791,Q32P28,P55081 3 +ABCB subfamily 0.798793354103885 1.6080682740592205 0.1078202266815764 1.0 0.3285871018654791 4 P08183 1 +SNARE protein 0.5712664493326636 1.5132370279067642 0.1302194618439265 1.0 0.3598693611736884 12 O95249,Q9P2W9,P56962,Q86Y82,O95721 5 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.7604772890239713 1.455712475513121 0.1454721196867694 1.0 0.3776059078069816 4 Q9UBX3 1 +Oxygenase 0.6737803855633955 1.3744119652289175 0.1693138236173306 1.0 0.4067043692920297 5 Q16850 1 +Phosphatase modulator 0.5704648071005248 1.3302718316461677 0.1834287245537922 1.0 0.423805669405099 10 P55209,Q99733 2 +Receptor 0.4881819160528422 1.29587506815719 0.1950185300564624 1.0 0.4345617277612157 28 Q567V2,Q9NR77,Q8WTV0,O75381,Q96GI7,A6NIH7,Q9UQB8 7 +Heterotrimeric G-protein 0.5867181371660207 1.2628608019395926 0.2066392090676778 1.0 0.4473372737301373 8 Q14344,Q9UBI6,Q8NHH9,P63218,P04899 5 +Chromodomain 0.7794453507340863 1.1314991092287712 0.2578450781363903 1.0 0.4996701378072614 3 Q13185,P45973 2 +Methyl-lysine/arginine binding protein 0.5914370476705961 1.019869292870545 0.3077904545512488 1.0 0.5524657933092425 5 Q13185,P45973 2 +CDK family 0.5897066067618013 1.0150363385436505 0.3100885058630802 1.0 0.5535901717429833 6 Q14004 1 +Serine protease 0.4458659953818191 1.0083471858578763 0.3132878178820664 1.0 0.555280376124234 27 Q96AE4,P34913,O14773,P61978,P42785,Q92945,Q9HB40,Q9H3G5,Q9Y6M1,Q96I24 10 +PKC alpha subfamily 0.9399869536855836 0.9687065822293258 0.3326916074977397 1.0 0.5713554227294805 2 P17252 1 +Glycosyltransferase 0.4429199888205928 0.9212283556886702 0.3569312169287562 1.0 0.5956167728918923 15 P04843,Q9BT22,Q86SF2,P46977,Q8NAT1,Q10472,Q8N128,Q8TCJ2 8 +PKC family 0.7214219935632105 0.9177048485308952 0.3587734086146372 1.0 0.5965546133199031 3 P17252 1 +F-type and V-type ATPases 0.4210506065856333 0.838181857454252 0.4019285748166574 1.0 0.6396394809396886 16 Q9Y487,P06576,P00846,Q93050,P24539 5 +CAMK group 0.590650259397476 0.7819882153777038 0.4342214993433217 1.0 0.6682235378392809 4 Q14012,O14936 2 +Metalloprotease 0.4152197324277085 0.7420202076087653 0.45807509229815 1.0 0.6867651096069578 38 Q9UIQ6,P22695,P42892,P55786,Q10713 5 +SLC35 family of nucleotide sugar transporters 0.8698630136986196 0.7402898623731147 0.4591241309183727 1.0 0.6867651096069578 2 Q8IXU6 1 +AGC group 0.4556553953466088 0.7352418629837233 0.4621922077733948 1.0 0.6885110889172481 10 P17252 1 +Phosphatase 0.3970378411249629 0.6753729137034619 0.4994388698728835 1.0 0.7192355956511213 27 Q9NPH0 1 +Reader 0.4105531460291229 0.627484903181026 0.5303414290928883 1.0 0.7375754445739694 12 P83916,Q13185,Q12888,P45973,Q6PL18,Q8WWQ0 6 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8307240704500911 0.62002752546043 0.5352396652124267 1.0 0.742164141505298 2 P30825 1 +Protease 0.3071425804341013 0.6122651531516139 0.5403623410728853 1.0 0.7451075445605989 105 Q9P275,P34913,Q5JRX3,P42785,Q9H3G5,P42892,P55786,P52888,O75844,Q9UIQ6,P61978,Q9HB40,Q10713,Q96AE4,Q8IYS1,Q8TCT9,Q92945,P22695,Q66K14,Q96RU2,Q96I24,O14773,Q9Y4W6,Q8NHP8,Q9Y6M1,Q6P179 26 +P-type ATPases 0.4904551789079107 0.5972887755841924 0.550314597107658 1.0 0.7539398356417852 6 P16615,P35670 2 +Histone 0.3994200130931295 0.5123295121796646 0.6084204139514644 1.0 0.7927418770633178 11 P07305,P16402,P16104,P10412 4 +Methyltransferase 0.3778606296589886 0.4613093817517275 0.6445766549592098 1.0 0.8117257322062658 12 P21964,Q96FX7,Q08J23 3 +Unclassified protein 0.3423665118749203 0.4544480617599466 0.6495063665080028 1.0 0.8133566732773401 18 P22392,P52789 2 +Bromodomain 0.4448073154800886 0.4220280898206757 0.6730045145153549 1.0 0.8240778038909559 6 Q86U86,O60885,Q6PL18,P25440,Q8WWQ0 5 +SLC56 Sideroflexins 0.7511415525114093 0.4000754167118376 0.6891009701711377 1.0 0.8318612562150977 2 Q96NB2 1 +V-type ATPase 0.4033951481373598 0.3939063677031834 0.6936501689361008 1.0 0.8339122014468952 8 Q93050,Q9Y487 2 +Oxidoreductase 0.2986850334248865 0.3798508811644723 0.7040561103560985 1.0 0.8374958618612058 117 Q13423,Q9BY49,Q15392,P00403,O15254,O15260,P30837,O95831,Q8N8N7,Q16850,Q9UDW1,Q8N4Q0,O94788,O43169,Q15067,P03915 16 +Esterase 0.367824145840791 0.3222371599757321 0.7472730350183348 1.0 0.8548108474827404 10 Q9UMR5 1 +Acyltransferase 0.3495506244734334 0.2858401282022464 0.7750005719156507 1.0 0.8676661523155549 11 P49354,P53609 2 +Microtubule binding motor protein 0.3389181812053051 0.2824132302730051 0.7776266714295201 1.0 0.8676661523155549 12 Q86Y91 1 +Epimerase/racemase 0.3474628975688714 0.2772201755665966 0.7816110486436862 1.0 0.8689017180533067 11 Q13011 1 +Other group 0.3391745348414483 0.2438234545416336 0.8073675543483498 1.0 0.8756764904422331 11 Q96KB5,Q9H4A3,P53350,Q96GD4 4 +Transporter 0.3373444060499583 0.2148366686923496 0.8298946628544397 1.0 0.8851318814233878 191 Q96A65,Q70HW3,P08195,P52292,Q15043,O14975,Q8TB61,P30825,Q15070,P56962,Q8IXU6,Q93050,Q6N075,Q96NB2,O43772,Q9Y6C9,Q8TAD4,Q9P2W9,Q03519,P00846,P08183,Q00765,P51572,Q99805,Q6NT16,Q9UBX3,P35670,P28288,O60645,Q9Y666,Q9Y487,Q9H6H4,O15439,P06576,Q9Y584,Q9Y6M7,Q9HD45,Q92973,Q8N1F7,P53985,P24539,Q12769,Q8NFH4,O95249,Q99808,P41440,Q08379,Q99567,Q9P253,Q9Y5K8,O95721,P30040,Q9H2V7,Q99523,Q9BQT8,P53680,Q86Y82,Q9UPT5 58 +Translation initiation factor 0.2914333327618181 0.1701547874249856 0.8648884075345378 1.0 0.896938030151945 19 O75153,P55010 2 +Glycosylase 0.6265492498369046 0.1529932793340264 0.8784035752113999 1.0 0.9053340146377972 2 P78549 1 +DNA glycosylase 0.6265492498369046 0.1529932793340264 0.8784035752113999 1.0 0.9053340146377972 2 P78549 1 +Dehydrogenase 0.3138571358908905 0.1209368369093601 0.9037410646578774 1.0 0.917595041121718 58 Q13423,Q9BY49,P30837,O95831,Q8N8N7,O94788,P03915 7 +Na+/K+-ATPases 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 0.9246194241273212 3 P05023,P05026 2 +Exoribonuclease 0.3184717179684689 0.0907032819548991 0.9277283627609028 1.0 0.9395495702374688 8 Q13868 1 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0a55aaa2909ad46dd35e669e09dc5ff324a16c94 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome non-ATPase regulatory subunit 9", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-Ketosteroid receptors", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5'-nucleotidase domain-containing protein 3", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "ATR subfamily", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase b", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcineurin-binding protein cabin-1", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Chaperone", "Chaperonin", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase epsilon subunit 2", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair protein complementing XP-C cells", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "Dystroglycan", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Ephrin-B1", "Epidermal growth factor receptor substrate 15", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2 subunit 3", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GMP synthase [glutamine-hydrolyzing]", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein 2", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General vesicular transport factor p115", "Geranylgeranyl transferase type-1 subunit beta", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucocorticoid receptor", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18A", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligand-dependent corepressor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lipoma-preferred partner", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MCU family", "MFS-type transporter SLC18B1", "MHC class II regulatory factor RFX1", "MIF4G domain-containing protein", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 14", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-bound signaling molecule", "Metal-response element-binding transcription factor 2", "Metallo-beta-lactamase domain-containing protein 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear envelope pore membrane protein POM 121C", "Nuclear factor NF-kappa-B p100 subunit", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable asparagine--tRNA ligase, mitochondrial", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FAM89A", "Protein FRG1", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein kinase c delta type", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with multiple splicing", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Rap guanine nucleotide exchange factor 6", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Ral-B", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoblastoma-associated protein", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC5 family of sodium-dependent glucose transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcolemmal membrane-associated protein", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Sedoheptulokinase", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase atr", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 6 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent multivitamin transporter", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-3", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TOPK family", "TP53-binding protein 1", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor IIA subunit 1", "Transcription initiation factor IIE subunit beta", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4B chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Type II PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 26B", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WNK family", "Winged helix/forkhead transcription factor", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 277", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter 7", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANAPC1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG7", "ATIC", "ATL2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKB", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CABIN1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CBR4", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC42", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKN2AIP", "CEBPZ", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHERP", "CHM", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "FAM177A1", "FAM89A", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS2", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2A1", "GTF2E2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KCTD12", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LCOR", "LDHA", "LDHB", "LETM1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPP", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM6", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARS2", "MAT2A", "MBLAC2", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "METAP1", "METTL1", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIF4GD", "MIPEP", "MMS19", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL44", "MRPL47", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NARS2", "NBN", "NCAPD2", "NCBP1", "NCL", "NCOA5", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NF1", "NFKB2", "NHP2", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NR3C1", "NRBP1", "NRDC", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OXA1L", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGGT1B", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPT1", "POGZ", "POLA2", "POLDIP3", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKACA", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAPGEF6", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNH1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT2", "SHPK", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP2", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM40", "TOP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TST", "TSTA3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UCHL5", "UCK2", "UGGT1", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP36", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VPS72", "VRK1", "VRK3", "WARS", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS4", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC4", "ABCD3", "ACOX1", "ACOX3", "ACP6", "AFG3L2", "AIFM1", "ALDH1A2", "ALDH1B1", "ALG1", "AP2S1", "ATAD2", "ATL2", "ATP1A1", "ATP1B1", "ATP2A2", "ATP5B", "ATP5F1", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP7B", "AURKB", "BAIAP2", "BCAP31", "BCAS2", "BRD2", "BRD4", "CALU", "CAMK1", "CASK", "CBX1", "CBX3", "CBX5", "CDK13", "CIRBP", "CLUH", "COMT", "COX2", "CPVL", "CYB5B", "CYB5D2", "CYP51A1", "DHCR24", "ECE1", "ECH1", "EIF5", "EPHX2", "ERAP2", "ERP29", "EWSR1", "EXOC3", "EXOC4", "EXOC7", "EXOSC2", "FAM177A1", "FAM89A", "FNTA", "FUBP1", "FUBP3", "FUS", "GALNT1", "GALNT7", "GNA13", "GNAI2", "GNG12", "GNG5", "GOLGA2", "GOSR1", "H1F0", "H2AFX", "HDGF", "HDGFL2", "HIST1H1D", "HIST1H1E", "HK2", "HM13", "HNRNPK", "IGF2BP2", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF18B", "KPNA2", "LNPEP", "LSM6", "MFAP1", "MFSD5", "MIA2", "MIA3", "MICU1", "MICU2", "MPV17L2", "MTCH2", "NAMPT", "NAP1L1", "NAP1L4", "ND5", "NME2", "NNT", "NONO", "NPEPPS", "NSUN2", "NTHL1", "NUCB1", "NUCB2", "NUP160", "NUP37", "NUP88", "NUP93", "OXA1L", "P3H1", "P3H4", "PARN", "PBK", "PBRM1", "PECR", "PEX14", "PGGT1B", "PGRMC1", "PGRMC2", "PHIP", "PITRM1", "PLBD2", "PLK1", "PM20D2", "PMPCA", "POMGNT2", "PPT2", "PRCP", "PRKCA", "PSPC1", "PTGR2", "PXMP2", "QKI", "RAVER1", "RBM14", "RBM17", "RBM19", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPMS", "RCN1", "RCN2", "REEP4", "REEP5", "RPN1", "SCAF4", "SCARB1", "SCPEP1", "SFPQ", "SFXN2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A20", "SLC25A21", "SLC25A26", "SLC27A2", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SNAP29", "SNRNP70", "SNRPA", "SORT1", "SPNS1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF7", "SRSF9", "SSR1", "STRBP", "STT3A", "STT3B", "STX12", "STX17", "STX18", "SUGP1", "SURF4", "TAF15", "TAP2", "TBC1D9B", "THOP1", "TIMM22", "TM9SF2", "TM9SF3", "TNPO1", "TP53BP1", "TPP1", "TRA2A", "TRA2B", "TRMT61A", "UNC119B", "UQCR10", "UQCRC2", "USP28", "USP36", "VPS18", "WNK1", "ZADH2", "ZFR", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..886367711a8f3920de5ea1c1cbefeaeafe1dfee3 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02dee42b12e175f04742678d80083fb1ca911c1b3401316ac3e371b3870df0cd +size 134435 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f582b044c73ad9da186a287ba09f70fb36c25951 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4dfee0f6c14abdce8a39186c3a4156526d1992068a7d234c13165aad7f05f38 +size 67576 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..46301cb6a628c5feadbf36eb967f8ae8b5155d66 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 766.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2dff578f75ae70149492e5119ef8ba1974ddbb75 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..26c50f79d490bd2ddd3cf07e1429548f51968393 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.1903443932733443 0.5160544521068289 0.6058163787314843 0.9758568295910692 0.8077551716419791 2367 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653 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eed9f2553598f3a4a09ba1772fea4e6e66fab746 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", 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"ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C3orf58", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPP", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG4", "COG6", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM89A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM160", "TMEM161A", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41B", "TMEM43", "TMEM65", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSPO", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AASDHPPT", "AATF", "ABCD3", "ABHD10", "ACADVL", "ACAT2", "ACBD3", "ACBD5", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ACTN4", "ADPGK", "AFG3L2", "AGTRAP", "AIFM1", "AIP", "AKAP1", "AKAP8", "AKAP8L", "ALCAM", "ALDH1A2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG11", "ALYREF", "AMOT", "ANAPC4", "ANAPC5", "ANAPC7", "ANKLE2", "ANXA1", "ANXA11", "ANXA4", "ANXA6", "ANXA7", "AP2S1", "APMAP", "ARFGAP2", "ARL5B", "ARMT1", "ARPC5", "ASH2L", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATP2A2", "ATP5B", "ATP5F1", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1D", "ATP6V1E1", "ATP7B", "ATPIF1", "ATRX", "ATXN10", "AUP1", "BAG5", "BAG6", "BAIAP2", "BASP1", "BCAP31", "BCAS2", "BCAS3", "BCKDK", "BCLAF1", "BCS1L", "BICD2", "BRAT1", "C19orf70", "CALU", "CAMLG", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCT2", "CD2BP2", "CD47", "CDK5RAP3", "CDV3", "CELF1", "CENPB", "CENPF", "CENPI", "CERS2", "CETN2", "CHCHD3", "CHCHD4", "CHMP1A", "CIAPIN1", "CIRBP", "CISD2", "CKAP4", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "CNNM4", "COA3", "COA7", "COG6", "COQ8A", "COX5A", "CPD", "CPOX", "CPVL", "CRK", "CRTAP", "CSTF2", "CTNNA1", "CTNND1", "CUTA", "CYB5B", "CYFIP2", "DCD", "DCTN2", "DCXR", "DDRGK1", "DDX17", "DDX20", "DDX28", "DDX5", "DHCR24", "DHPS", "DHRS4", "DHRS7", "DIABLO", "DLG1", "DMAP1", "DNAJC3", "DNAJC7", "DOHH", "DPF2", "DSG2", "DTNBP1", "DTYMK", "DUSP9", "EBNA1BP2", "ECH1", "ECI1", "ECSIT", "EEFSEC", "EFNB1", "EI24", "EIF3J", "EIF3L", "EIF4B", "EIF5", "EMD", "EPN1", "EPS15", "ERBIN", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERP29", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC2", "EXOSC5", "EXOSC7", "FAM208A", "FAM213A", "FAM8A1", "FARSB", "FECH", "FGFR1OP", "FIP1L1", "FKBP10", "FKBP14", "FKBP7", "FLAD1", "FN3KRP", "FNTA", "FOXK1", "FOXRED1", "FRG1", "FUBP1", "FUBP3", "FUS", "GADD45GIP1", "GALNT1", "GALNT7", "GAPVD1", "GAR1", "GCAT", "GDAP1", "GET4", "GHDC", "GHITM", "GINS4", "GLCE", "GLG1", "GMPPB", "GNG12", "GNG5", "GNS", "GOLGA2", "GOLGA5", "GOLIM4", "GOSR1", "GTPBP2", "H2AFX", "H3-3A*", "HACD3", "HADH", "HAUS1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HGS", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-A", "HM13", "HMCES", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPLL", "HNRNPR", "HNRNPUL1", "HS2ST1", "HSD17B11", "HSPA13", "HSPD1", "HSPE1", "IARS2", "IDH3B", "IGBP1", "IGF2BP2", "IK", "IMMT", "INA", "INTS3", "IPO8", "ISOC2", "IST1", "ITM2C", "JAGN1", "JAM3", "KCTD12", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", 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file mode 100644 index 0000000000000000000000000000000000000000..6e1e99e738b914ef2a11909fbec057f6c5ffb141 --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b4bc82094ed70455d86a5700cd961e3529c87031718e5938fb8a0c22c19df78 +size 73790 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fa8e375b5a760190a5746a582418d93199ca2456 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleotide metabolism 2 9 2.2476806347090736 0.0245965617099297 2.825242718446602 9.657766990291265 0.1031324982165795 0.4462534906167557 2.086373657371837 1.6478473348312213 1.124114753923129 0.2978561945400932 0.1701770965395962 0.1006582454154426 0.191600110602388 0.0152248647419399 0.088385561156941 +Translocation 21 51 2.149738028443215 0.0315759425906816 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0244447876640009 2.6116330706367664e-05 0.0007060425621212 6.740249353507396e-05 6.16515920781819e-08 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..761e359e05af4e29c0200d30ed9666f508c3f763 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 168, + "title": "Average number of proteins per term", + "value": 29.636904761904763 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..daed7112074e9da6b3249702997b9443fa8caf55 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37935782e6a7d38bca9579bb975a817001c42f70 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleotide metabolism 0.7745175854647202 2.2476806347090736 0.0245965617099297 0.9847608971537009 0.4272613322136852 9 Q969T7,P00813 2 +Translocation 0.5737596742596296 2.149738028443215 0.0315759425906816 0.9954394661130797 0.4822507595667741 51 Q99595,O60830,Q8N4Q1,Q9BTX1,P41208,P62072,Q3ZCQ8,Q9NS69,P61970,O14925,Q8NFH5,Q8TD16,O75381,Q9Y584,P12270,Q99442,Q8N1F7,Q12769,Q8NFH4,Q15629,Q9H173 21 +Amino-acid transport 0.6540335815096873 1.590118209758127 0.1118081620689008 0.9999999977657144 0.7341662717296213 8 P08195,Q15758,P30825,Q9H9B4,Q96NB2 5 +Purine salvage 0.7023119477517044 1.4968272038503825 0.1344382258274064 0.9999999999707534 0.8066293549644383 5 Q13126 1 +Sensory transduction 0.6154290268925336 1.403202328172168 0.1605565135469566 0.99999999999983 0.8991164758629573 8 Q9H6K4,O43924,P50897,Q6P4Q7 4 +Hydrogen ion transport 0.4820616331228014 1.3317842523851635 0.1829310941297373 0.9999999999999982 0.9620741259146552 20 Q15904,Q9Y487,P36543,O75964,P06576,P00846,Q93050,P24539 8 +Vision 0.6079802491917988 1.2213734567259764 0.2219446523772268 1.0 0.9620741259146552 7 Q9H6K4,O43924,Q6P4Q7 3 +Calcium transport 0.5370046203028327 1.1558342918835949 0.2477489435725655 1.0 0.9664974309807448 10 Q9H4I9 1 +Respiratory chain 0.4636140151838434 1.1031856509835152 0.2699465513215013 1.0 0.9664974309807448 32 Q86Y39,Q6DKK2,P00403,O96000,O43676,Q9UDW1,P22695,Q9P0J0,Q9Y6M9,P03915,Q96CU9 11 +ATP synthesis 0.5466869095494253 1.0662846277718898 0.2862949963247696 1.0 0.9664974309807448 8 P00846 1 +Symport 0.5255983203209186 1.0262165974349493 0.3047894996557052 1.0 0.9664974309807448 9 Q9Y6M7,Q15758,Q9Y666,P53985 4 +Cholesterol metabolism 0.4315036344129208 0.992428035133508 0.3209887686869708 1.0 0.9664974309807448 20 Q15392,Q15126,P37268,P35610,Q16850,O15118,O75477,Q14739,Q9UHB6 9 +Glyoxylate bypass 0.9403131115459852 0.969797566201638 0.3321474062345304 1.0 0.9664974309807448 2 P48735 1 +Ion transport 0.4001948114342247 0.9484547130159606 0.3428980172296363 1.0 0.9664974309807448 62 Q15904,Q15043,Q8TDW0,Q93050,P21796,Q6N075,Q9H4I9,Q8TAD4,O75964,Q96AQ8,P00846,P35670,Q6P4Q7,Q9Y666,Q9Y487,P06576,Q9Y6M7,P45880,P24539,P36543,Q9BPX6,Q9H0H5 22 +Sterol metabolism 0.424235273688546 0.9294180631004066 0.3526724703068109 1.0 0.9664974309807448 21 Q15392,Q15126,P37268,P35610,Q16850,O15118,O75477,Q14739,Q9UHB6 9 +Cilium biogenesis/degradation 0.4246739619199215 0.9154476770272276 0.3599566588314793 1.0 0.9664974309807448 17 A6NIH7 1 +Detoxification 0.9161774298760532 0.8896815245306474 0.3736369172422129 1.0 0.9664974309807448 2 P07099 1 +Aromatic hydrocarbons catabolism 0.9161774298760532 0.8896815245306474 0.3736369172422129 1.0 0.9664974309807448 2 P07099 1 +Cholesterol biosynthesis 0.4589169682486136 0.8885694879071617 0.3742344953279637 1.0 0.9664974309807448 12 Q15392,Q15126,P37268,Q16850,Q14739 5 +Porphyrin biosynthesis 0.558214402261777 0.878457633925591 0.3796954193138639 1.0 0.9664974309807448 5 P22830,P50336 2 +Sterol biosynthesis 0.4474908606673111 0.8613289093886067 0.3890569178050034 1.0 0.9755457043468742 13 Q15392,Q15126,P37268,Q16850,Q14739 5 +Steroid metabolism 0.4074941106294431 0.804004060551946 0.4213946299334703 1.0 0.9932181625795128 22 Q15392,Q15126,P37268,P35610,Q16850,O15118,O75477,Q14739,Q9UHB6 9 +Steroid biosynthesis 0.3990951231206192 0.7932109576575829 0.4276549243888938 1.0 0.9932181625795128 19 Q15392,Q15126,P37268,Q16850,Q8NBQ5,Q9H3P7,Q14739 7 +Sphingolipid metabolism 0.4631352614321261 0.7731746637343804 0.4394190184483983 1.0 0.9932181625795128 10 Q06136 1 +mRNA transport 0.3598195256829896 0.686826183061435 0.4921922680677677 1.0 0.9973410616275168 66 Q8NFH4,P22626,P84103,P61970,Q8NFH5,Q96PU8,Q8TD16,Q92945,P12270,Q16629,Q07955,Q9BTX1,Q9Y6M1,Q53F19,Q8N1F7,P09651,P41208,Q12769 18 +Peroxisome biogenesis 0.5384450138855335 0.5876880238194424 0.5567417156285805 1.0 1.0 4 P56589 1 +Phospholipid metabolism 0.3913177950835402 0.5832429697370418 0.5597297483502235 1.0 1.0 14 Q96N66,Q9NPH0 2 +Neurogenesis 0.3901930462972739 0.5735225621311023 0.5662909270576835 1.0 1.0 45 Q8WUJ1,Q16352,P98172,P55209,Q969G3,Q9NQC3 6 +Adaptive immunity 0.3742157283239753 0.5583910854021232 0.5765773588551357 1.0 1.0 16 P04439,Q13740,Q03519,Q6P179,P05771 5 +Electron transport 0.3822201991155857 0.5144120144248716 0.6069639611125452 1.0 1.0 45 Q86Y39,Q6DKK2,P00403,O96000,O43676,Q16134,Q9UDW1,P22695,Q9P0J0,Q9Y6M9,O43169,P03915,Q96CU9 13 +Myogenesis 0.4476998578811878 0.5022447828117971 0.6154953450956215 1.0 1.0 7 P85037 1 +Zinc transport 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 1.0 3 Q8TAD4 1 +mRNA splicing 0.3408531586514968 0.3726459049018188 0.7094120025462045 1.0 1.0 176 Q9Y5S9,O75940,P84103,P62312,Q8IWZ8,Q96PU8,P23246,Q13242,Q15233,P52597,Q9UHI6,P61978,P67809,Q9NW64,Q07955,O60506,O75934,Q9UKM9,P51991,P52756,O95400,P22626,Q9ULX6,Q9P013,Q14004,P09012,Q92945,Q5BKZ1,P31943,Q13595,Q12972,Q9BWF3,O75494,O43390,Q92841,P49756,Q96I25,Q9Y2W1,Q16629,P98175,P62995,P07910,Q96E39,Q9UKA9,P55081,P38159,P09651 47 +mRNA processing 0.3535723079411032 0.2901625974521732 0.7716918487462687 1.0 1.0 207 Q8N684,O75940,P84103,P62312,Q96PU8,P31942,Q13242,Q15233,P52597,Q9UHI6,P61978,P08621,P67809,Q86U42,Q07955,O60506,O75934,Q9UKM9,P51991,P52756,O95400,P22626,Q9P013,Q14004,P09012,Q92945,Q5BKZ1,Q53F19,O75525,P31943,Q9BWF3,O75494,O43390,Q92841,P49756,Q6UN15,Q96I25,Q9Y2W1,Q16629,P98175,P07910,P62995,Q96E39,Q9UKA9,P55081,P38159,P09651,Q6P087 48 +Transcription termination 0.4995106035888885 0.2301569325532002 0.8179698263514739 1.0 1.0 3 Q9UNY4,Q9H0D6 2 +Heme biosynthesis 0.3799412508020574 0.2099576043552287 0.8337007622944361 1.0 1.0 6 P22830,P50336 2 +Tricarboxylic acid cycle 0.2884816862951042 0.1568866196500039 0.8753342052409898 1.0 1.0 19 P48735 1 +Fatty acid metabolism 0.3244620904915103 0.1351081607694346 0.8925263579825231 1.0 1.0 49 P42126,Q9UKU0,Q9BY49,P23786,O15254,O15121,Q16836,O14975,P33121,Q13011,Q15067,Q8NCC3 12 +Branched-chain amino acid catabolism 0.5968688845401053 0.1151198937453022 0.9083500918054191 1.0 1.0 2 Q6NVY1 1 +Sodium/potassium transport 0.4339314845024409 0.1110331475033164 0.911590061331365 1.0 1.0 3 P05023,P05026 2 +Lipid transport 0.2718415320627662 0.1003209865351765 0.9200894966944816 1.0 1.0 18 Q9H4L5,Q9H2V7,O15118 3 +Viral RNA replication 0.5694716242661294 0.0872101122485324 0.9305045015718 1.0 1.0 2 Q15365 1 +Notch signaling pathway 0.4101141924959237 0.0804773234329279 0.935857631005924 1.0 1.0 3 Q9NVX2,Q92542 2 +Phagocytosis 0.3843393148450249 0.0546373810067173 0.95642735748709 1.0 1.0 3 P20339,Q14185 2 +Virus entry into host cell 0.5218525766470786 0.0531232455744507 0.9576337103105952 1.0 1.0 2 P49790 1 +Viral penetration into host nucleus 0.5218525766470786 0.0531232455744507 0.9576337103105952 1.0 1.0 2 P49790 1 +Stress response 0.2825929957404822 0.0426570904411731 0.9659748852793146 1.0 1.0 27 O95197,Q14011,Q13217,P98179,P61604 5 +Glutathione biosynthesis 0.4951076320939207 0.040726595482678 0.9675138590516176 1.0 1.0 2 P48507 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6af7ae0c785210377678e9c82b8b0215633500e9 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDOA", "ALDOC", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEX1", "API5", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATR", "ATRX", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "CACYBP", "CAD", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CBR4", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC59", "CCDC86", "CCDC93", "CCNB1", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPV", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "COG6", "COG7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPZ1", "COQ5", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF13", "DCAF16", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPYSL2", "DSC3", "DSG2", "DST", "DTNBP1", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GINS2", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP3", "GTPBP4", "GUF1", "GYS1", "H2AFX", "HACD3", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JUP", "KARS", "KAT7", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF18A", "KIF18B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LPP", "LRP1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1S", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METTL1", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICAL3", "MICU1", "MID1", "MIF", "MIF4GD", "MINDY3", "MKI67", "MLEC", "MMS19", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MRE11", "MRGBP", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MYBBP1A", "MYCBP", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFKB2", "NGEF", "NHP2", "NIP7", "NISCH", "NKRF", "NLE1", "NME1", "NME2", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NR3C1", "NRDE2", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OGDH", "OGT", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHKB", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMVK", "PNKP", "PNN", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POP1", "PPAT", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP2", "RANBP3", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN3", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPC24", "SPC25", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYS1", "TAF6L", "TALDO1", "TAMM41", "TAP2", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TCEA1", "TCERG1", "TCF20", "TDP2", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TK1", "TLK2", "TLN1", "TMCO1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM214", "TMEM30A", "TMEM41B", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOLLIP", "TOMM22", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT112", "TRMT61A", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSR1", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TUBB2B", "TUFM", "TWF2", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VTA1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR41", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WTAP", "XAB2", "XIAP", "XPC", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "ZBED4", "ZC3H11A", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMYM2", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ACBD3", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL6", "ADA", "AKAP8L", "ALCAM", "ATP1A1", "ATP1B1", "ATP5B", "ATP5F1", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7B", "BCAS2", "BICD2", "CD2BP2", "CDK13", "CETN2", "CHCHD4", "CIRBP", "CNNM4", "COX2", "CPSF7", "CPT2", "CWC15", "CYB5B", "CYB5D2", "CYP51A1", "DDX17", "DDX20", "DEGS1", "DHCR24", "DNAJC3", "DOCK1", "ECH1", "ECI1", "EFNB1", "EPHX1", "ERAP2", "ERLIN1", "ETFDH", "FDFT1", "FECH", "FIP1L1", "FOXK1", "FOXRED1", "GCLM", "HADH", "HIBCH", "HLA-A", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPR", "HSD17B11", "HSPE1", "IDH2", "IGF2BP2", "INA", "KDSR", "KHDRBS3", "KHSRP", "LBR", "LIMA1", "LRRC8C", "LSM6", "MBOAT7", "MCUR1", "MFAP1", "MFSD5", "MICU1", "MTAP", "NAP1L1", "NCBP3", "NCSTN", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NLE1", "NONO", "NPC1", "NT5C3B", "NUP153", "NUP160", "NUP35", "NUP37", "NUP93", "NUTF2", "OPA3", "OSBPL3", "PABPN1", "PCBP1", "PDE6D", "PECR", "PEX14", "PEX3", "PLA2G15", "PMVK", "PPOX", "PPP1R8", "PPT1", "PRKCB", "PTBP2", "QKI", "RAB5A", "RACGAP1", "RALY", "RBM10", "RBM17", "RBM22", "RBM25", "RBM3", "RBM4", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RPUSD3", "RTN3", "RTN4", "SEC62", "SFPQ", "SFXN1", "SFXN2", "SIL1", "SLC12A7", "SLC16A1", "SLC1A5", "SLC27A2", "SLC30A5", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SMARCE1", "SMDT1", "SMNDC1", "SNRNP70", "SNRPA", "SOAT1", "SPNS1", "SRSF1", "SRSF10", "SRSF3", "SRSF7", "SRSF9", "SUGP1", "SYNCRIP", "TAP2", "THRAP3", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM50", "TOMM22", "TPR", "TRA2A", "TRA2B", "TRAM1", "TTC19", "TTF2", "UNC119B", "UQCR10", "UQCRC2", "VDAC1", "VDAC2", "XRN2", "YBX1", "ZNF326"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0fd36c023034c991a08916c235155f026a681c2f --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 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0000000000000000000000000000000000000000..543f9c6bf48ba5dd2c6c3cd7bdf352b44d9c4e1b --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56f7d4476eb8dd15db8511d42111693e028187b871ba0d5f3f74beafc5fbfb5e +size 71876 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..07afd3b7ee3c836bd4bda276868aa5ea6f58d30e --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 17 98 2.185241088626863 0.0288711743096099 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 7.851256786659314e-05 0.0011826603259271 3.090226013595508e-05 5.052548674440096e-05 5.64845215444778e-05 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..24fdf0c91ca78c2ebdb1d2d69e4f898d7f5422b6 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 115, + "title": "Average number of proteins per term", + "value": 21.17391304347826 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f33cfdc247f80347a9f76e2ebcdec1b9b94cffc3 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..edef987d1520851bb0043600fe24b8d647884753 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,29 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.4178420462914377 2.185241088626863 0.0288711743096099 0.9655779118032471 0.6235298263159686 98 Q5U5X0,Q86Y39,Q6DKK2,Q70HW3,P00403,O43676,Q9Y584,O95831,P00846,P22695,P03915,Q8NI60,Q9BQT8,Q9Y6M9,Q9Y2R0,Q9UBX3,Q96CU9 17 +Mucopolysaccharidosis 0.7209030447425104 1.5761783110087282 0.1149847154878775 0.9999992068803952 0.7768119743299831 5 P54802,P15586 2 +Amyotrophic lateral sclerosis 0.5413928341135381 1.397553692429029 0.1622471324788641 0.999999998560104 0.7768119743299831 13 P50995,P35637,Q96CV9 3 +Retinitis pigmentosa 0.540643511437486 1.3932825849092791 0.1635343547806593 0.9999999987934856 0.7768119743299831 13 O43837,Q13868,Q8N2K0,P00846,O75695 5 +Emery-Dreifuss muscular dystrophy 0.6687138664447714 1.3526120039756573 0.1761796155175345 0.9999999997907134 0.7768119743299831 5 P02545,P50402 2 +Leukodystrophy 0.4869625028033439 1.3162472705699346 0.1880910625460119 0.9999999999607948 0.7768119743299831 17 P10809,O15121 2 +Congenital muscular dystrophy 0.6391066832370895 1.229732132705216 0.218797429866564 0.9999999999995346 0.7768119743299831 6 P02545,Q8NAT1 2 +Limb-girdle muscular dystrophy 0.5618290581384686 1.2094932208046745 0.2264734139836186 0.9999999999998505 0.7768119743299831 9 Q5JTV8,P02545,Q8NAT1,O14979 4 +Peroxisome biogenesis disorder 0.6968945838738 1.2012192891172773 0.2296661489323428 0.9999999999999072 0.7768119743299831 4 P56589,O75381 2 +Zellweger syndrome 0.6968945838738 1.2012192891172773 0.2296661489323428 0.9999999999999072 0.7768119743299831 4 P56589,O75381 2 +Dystroglycanopathy 0.6133014634201679 1.1137928515305016 0.265368064400155 0.9999999999999996 0.8247926325950765 5 Q14118,Q8NAT1,Q9Y5P6 3 +Leber hereditary optic neuropathy 0.970319634703195 1.070985529432103 0.2841759362161387 1.0 0.8379546837142551 2 P00846 1 +Dystonia 0.5629965557072986 1.0138448768758652 0.3106567777057152 1.0 0.841767122335147 7 Q9ULV3,Q15043,O60220,P51572 4 +Osteogenesis imperfecta 0.4910822051463051 0.8527004084197096 0.3938254643497405 1.0 0.9578238636279418 9 Q32P28,Q96AY3 2 +Leigh syndrome 0.4646283530630448 0.8465899364737303 0.3972237251347883 1.0 0.9578238636279418 11 P00846 1 +Hirschsprung disease 0.901174168297448 0.8405905925326742 0.4005773307424198 1.0 0.9578238636279418 2 P42892 1 +Schizophrenia 0.693505448146988 0.8171088112293741 0.4138662479950812 1.0 0.9578238636279418 3 P21964 1 +Neuronal ceroid lipofuscinosis 0.6854812398042298 0.7885906881270116 0.4303512751848843 1.0 0.9578238636279418 3 O14773,P50897 2 +Proto-oncogene 0.4167972342461449 0.7703324075675272 0.4411027372392544 1.0 0.9578238636279418 44 Q01844,P42566,P46108,P06753,Q92733,Q06136,Q03164,O96028,Q92734,P35637,P12270,Q01105,P17252,Q92804,Q16204 15 +Primary microcephaly 0.447328843154936 0.5007118750093896 0.6165739136754973 1.0 1.0 7 Q86XL3 1 +Allergen 0.780821917808207 0.4775526835142176 0.6329686150482008 1.0 1.0 2 Q9BPX6 1 +Ciliopathy 0.3867066359743433 0.325338759057131 0.7449246995205276 1.0 1.0 8 O43924,Q9UBB4,P49454,Q7Z4L5 4 +Spinocerebellar ataxia 0.3601757556257858 0.2906741030739564 0.7713005795500776 1.0 1.0 10 O14773,Q8IV08,Q9Y4W6 3 +Congenital disorder of glycosylation 0.3155687520158092 0.2739520069811956 0.7841215039952405 1.0 1.0 17 Q8N511,Q15904,Q2TAA5 3 +Joubert syndrome 0.5022126775597202 0.2361479911097027 0.8133178352815957 1.0 1.0 3 O43924 1 +Microphthalmia 0.3184076043218806 0.0668104157348672 0.9467326313810224 1.0 1.0 6 P53701 1 +Deafness 0.308833136487356 0.0457524031950966 0.9635075957995008 1.0 1.0 47 Q9NSE4,Q13868,Q16740,O95831,Q13217,P51572,Q9NWM8,Q9NR28,Q15067 9 +Dyskeratosis congenita 0.2639477977161539 0.0062730900333133 0.9949948311408638 1.0 1.0 3 Q9NX24,O95453 2 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5146faeedfc914b419c0f7884dbbc80bb8e430eb --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pseudohermaphroditism", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ANAPC1", "ANK3", "ANKLE2", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APC", "APEX1", "APPL1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7B", "ATR", "ATRX", "ATXN10", "AURKB", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRB", "BMS1", "BPTF", "BRAT1", "BRD4", "BUB1B", "C19orf70", "C1QBP", "C3orf58", "CAD", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCT5", "CDC16", "CDC27", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDKAL1", "CENPF", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD7", "CHD8", "CHM", "CHMP1A", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCN7", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COG6", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEGS1", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF2S3", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC9", "EZR", "FADS2", "FAF1", "FAM120A", "FAM3C", "FAM50A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXO3", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GCDH", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPI", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2E2", "GTF2I", "GTPBP2", "GTPBP3", "GUF1", "GUSB", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2R", "ILF3", "IMPAD1", "IMPDH2", "INF2", "INTS1", "INTS12", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KMT2A", "KTN1", "L2HGDH", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3BP", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPP", "LRBA", "LRP1", "LRPPRC", "LSS", "LTA4H", "LYN", "LYRM7", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK3", "MARS", "MARS2", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MESD", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMAB", "MMADHC", "MOGS", "MORC2", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCSTN", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NF1", "NFKB2", "NFU1", "NHLRC2", "NHP2", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NPC1", "NPM1", "NR3C1", "NSD2", "NSD3", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OGDH", "OGT", "OPA1", "OPA3", "OPTN", "OSGEP", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PANX1", "PARD3", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKB", "PICALM", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RNASEH2A", "RNASET2", "RNF213", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SH3PXD2B", "SHOC2", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", 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https://git-lfs.github.com/spec/v1 +oid sha256:6b68ec07acdfe8405e34b0c31921477b0e608b6e3b7993dd72b3f63456c5b5f3 +size 72586 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5a8be75c78eaee5b5191a155350b1baa47cbea07 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protease 23 75 2.1572880788400184 0.0309832252838566 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0446810230031509 0.024205830616191 0.0232762416433923 0.0520606049377112 0.008298589623976 +Translocase 6 23 2.0312168943009032 0.0422329973390769 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0001440207737622 0.2516504230112798 2.225319400554361e-05 0.0005673930602398 0.0254457366029634 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f5622f5991c623ea6da5f30ac395e94f6e8e3706 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 37.71134020618557 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3534f93f55eb319ff8d8ac425f0a408b8363d373 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0f29f2ddea0d3a31633505ecaa83406fcb3c4840 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,22 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protease 0.4458360772721341 2.1572880788400184 0.0309832252838566 0.9527789503973556 0.4232839988682226 75 Q9P275,P28072,Q5JRX3,P42785,Q9H3G5,P42892,Q99436,P55786,P52888,Q4J6C6,Q96FZ2,O75844,Q9UIQ6,Q9HB40,P28074,P81605,Q8TCT9,O75976,Q16740,Q96RU2,O14773,Q9Y4W6,Q6P179 23 +Translocase 0.5924784150801703 2.0312168943009032 0.0422329973390769 0.984787260178896 0.4232839988682226 23 Q13423,P00403,O15439,Q9HD20,P08183,P03915 6 +Porin 0.9058308968168788 2.025236345081802 0.0428431012952708 0.9856990797453568 0.4232839988682226 4 P21796 1 +Carboxypeptidase 0.771662172022498 1.7991189844277875 0.0719998612083085 0.999288524427689 0.4747656180646016 6 Q9HB40,P42785,Q9H3G5 3 +Threonine protease 0.9008156606851504 1.5846672501749983 0.1130419565353821 0.9999911570244984 0.5730524559876402 3 P28072,Q99436 2 +Metalloprotease 0.51667856713221 1.5058350171940174 0.1321095316182936 0.9999989257703912 0.5730524559876402 26 O75844,Q5JRX3,O75976,Q9UIQ6,Q9Y4W6,P42892,P55786,P52888 8 +Heparin-binding 0.6601997552529469 1.3214356054142804 0.1863561605700665 0.9999999979482188 0.5730524559876402 6 P10586,P51858 2 +Guanine-nucleotide releasing factor 0.4936702376475876 1.2899903407613214 0.1970540118514683 0.9999999994317044 0.5730524559876402 16 P80303,Q02818 2 +Monooxygenase 0.6906587540367011 1.176251843658641 0.2394942530388024 0.9999999999970696 0.5735545847451475 4 Q9BU89 1 +Aminopeptidase 0.5006347426454058 1.120345957436153 0.262566364934921 0.9999999999998525 0.5735545847451475 12 P55786 1 +Transducer 0.5297854631538151 1.1181476158080423 0.2635039528816119 0.9999999999998695 0.5735545847451475 10 Q14344,Q9UBI6,P02786,P63218,P04899 5 +Serine protease 0.5567482061943833 1.1157114924046028 0.264545649659565 0.9999999999998864 0.5735545847451475 8 Q16740 1 +Repressor 0.3410090542249718 0.957292165706214 0.3384198084967891 1.0 0.6079022485960841 115 Q96PK6,P85037,Q9NPF5,Q9NX63,Q8NEY8,Q13242,Q15233,P61978,P67809,Q8NB78,Q13185,Q14011,Q8IXH7,O75446,O14979,Q9UBK9,Q16629,P62995,P51858,Q9H0E3,P38159 21 +Exonuclease 0.4196955364296844 0.8990842268714255 0.3686077989589422 1.0 0.6500901181639527 21 Q9UQ84,Q8IV08,Q9Y3B8 3 +Rotamase 0.3879991195925176 0.676122519277595 0.4989628601341709 1.0 0.7754083611860971 22 Q96AY3,Q9NWM8 2 +Receptor 0.4034165956292922 0.6563333867280396 0.5116096403702084 1.0 0.7754083611860971 39 Q9UNN8,Q9NS69,Q9Y5M8,Q9Y2W1,P30825,Q99523,Q8WTV0,Q14108,O00264,O15031,O15118,P11717,P10586,O15173 14 +Prenyltransferase 0.5067257606067528 0.477191940018026 0.6332254499954728 1.0 0.8283196509689489 4 P53609 1 +Glycosyltransferase 0.3372046712188085 0.2572011336186757 0.7970235089390312 1.0 0.9095444749068944 32 Q13126,Q8NAT1,P43490 3 +Oxidoreductase 0.3213173470157828 0.1884321942006118 0.8505378643752193 1.0 0.9593275912139102 170 Q8NBX0,Q16850,P30519,Q9UHG3,O94788,Q15067,Q9BU89,O15254,O15121,P30837,O95831,Q8N4Q0,Q8NB78,O75874,P48735,Q15392,Q06136,Q32P28,Q9BY49,Q8N8N7 20 +Acyltransferase 0.3171664832735565 0.1505689886345985 0.8803157259282375 1.0 0.9815014415521728 32 Q86UY6,Q8NCC3,Q9BWD1,P23786 4 +Serine protease inhibitor 0.4804305283757203 0.0355904341261333 0.9716089359524224 1.0 1.0 2 P30086 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7d7e2b93451294ac2200cc9b1523b736ac78d629 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATR", "ATRX", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BANF1", "BAZ1B", "BAZ2A", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPHL", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BRMS1L", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C12orf43", "CABIN1", "CAD", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBR1", "CBR4", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC37", "CDC42", "CDC5L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHM", "CHMP1A", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCD", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EFNB1", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "F11R", "FADS2", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDE1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLCE", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INF2", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KRR1", "L2HGDH", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD3", "LIG3", "LIMA1", "LIPA", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MARC1", "MARC2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MATR3", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFN1", "MFN2", "MGEA5", "MGME1", "MGST2", "MGST3", "MICAL3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTF2", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NAT10", "NAXE", "NCBP3", "NCL", "NCOA5", "ND5", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFKB2", "NGEF", "NHP2", "NIFK", "NIP7", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRDC", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTULIN", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDE8A", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHKB", "PI4K2A", "PIAS2", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R8", "PPP3CA", "PPP4C", "PPP5C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMD9", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFX1", "RHOT1", "RHOT2", "RIC8A", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT2", "SHPK", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLK2", "TMCO1", "TMEM109", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TST", "TSTA3", "TTF2", "TUFM", "TWF1", "TWF2", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTRN", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "WARS", "WARS2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WTAP", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "ZADH2", "ZBED4", "ZC3H14", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687"], "leading_proteins": ["ABCB1", "ABCC4", "ACAT2", "ACOX1", "ACOX3", "AFG3L2", "AIFM1", "ALDH1A2", "ALDH1B1", "ATP13A1", "CBX3", "CHCHD3", "CIRBP", "CLPP", "COX2", "CPD", "CPT2", "CPVL", "CYP51A1", "DCD", "DEGS1", "DHCR24", "DMAP1", "DOHH", "ECE1", "ERAP2", "EXO1", "FKBP10", "FKBP14", "FOXK1", "GNA13", "GNAI2", "GNG12", "GNG5", "HDGF", "HM13", "HMCES", "HMOX2", "HNRNPDL", "HNRNPK", "IDH1", "IDH2", "IGF2R", "KDM1B", "KDSR", "LNPEP", "MTAP", "NAA40", "NAMPT", "ND5", "NELFCD", "NNT", "NONO", "NPC1", "NPEPPS", "NUCB1", "NUCB2", "P3H1", "PCYOX1", "PEBP1", "PECR", "PGGT1B", "PGRMC1", "PGRMC2", "PITRM1", "PLA2G15", "PLD3", "PLXNB2", "POMGNT2", "PPHLN1", "PRCP", "PREPL", "PROCR", "PSMB5", "PSMB6", "PSMB7", "PTGR2", "PTPRF", "RBM14", "RBMX", "REXO2", "SAP130", "SAP30", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SLC7A1", "SORT1", "SRPRB", "SRSF7", "SRSF9", "TFRC", "THOP1", "THRAP3", "TOMM22", "TPP1", "TRA2B", "USP28", "USP36", "UXT", "VDAC1", "YBX1", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8cf075b4b35ee08d577dadffb9572d767466fb0a --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted secreted proteins", "1": "Predicted membrane proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ad1441e0a518944cc323fe060784d838b47861bb --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f81f5c025c5d3fda2be2550e6c7433cada859f6660bff3638a0e09f2bb1b5e14 +size 136968 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..72a8f04c503308a7f2093a976836b7a304de757e --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9387fb53b0eacfb93b70b87014b7c8342e352f6b525ec924aeb7e2994c0658d +size 144279 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..50e8a6708a47a7644788cfb87bdbf29d7d518d92 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1067eaa3e86d4c87faa6ffbee5f489f4ee6e22195691d468903bbbe3fbd595a +size 80280 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..12930ac497a27e39c14b7865dff532051809d60a --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 471.0 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5d9089ae319f48faf8bbe5959372e0c488890e4b --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7bb307ca9ca77001f0ef07b3ecc0044c8866ad15 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted secreted proteins 0.5512418377615722 1.917621279225667 0.0551590499488969 0.6962384079821816 0.3861133496422788 49 Q8WUJ1,Q9H6E4,P51858,Q9BTY2,P80303,Q9HB40,O60888,Q8N128,Q02818,P43490,Q15165,Q9UMX5 12 +Predicted membrane proteins 0.4588076996388024 0.7453515760859486 0.4560592094015803 0.9999972036972398 1.0 555 Q9Y262,Q99595,O60830,Q9HDC9,Q70HW3,P00403,P08195,Q5VW38,O00461,Q8NBX0,P30519,Q15070,Q8IXU6,P42892,Q10472,Q9H3K2,Q96NB2,O43772,Q9H4I9,Q9NPR9,Q13505,Q6RW13,Q567V2,Q9NS69,Q3ZCQ8,Q9NR77,Q6UW68,Q9UIQ6,O15121,O43676,O14925,O95831,P00846,Q96AQ8,Q8IZA0,P08183,Q8WTV0,Q86UP2,Q8IY95,Q92804,Q99805,Q6NT16,Q8NCC3,Q9Y2R0,Q9UBX3,Q5T8D3,Q14739,P35670,P31350,Q13423,Q15392,Q8IV08,Q9H1E5,Q9Y487,Q06136,O15439,O15260,P49069,Q9HD20,Q99442,Q8TAA9,Q92615,O43169,Q8N511,Q86XL3,P03915,Q9H061,Q9H4I3,O95772,O60725,P41440,Q15629,O95197,P43307,Q9H2V7,Q9NX00,Q9UNN8,O43657,Q9UBU6,Q16850,Q9UDW1,Q8TDW0,Q93050,Q9BTX1,O15173,Q9H6K4,Q8TAD4,Q8NC54,Q9P2W9,Q03519,O75964,Q9Y282,O75381,P56589,Q9NQC3,Q16706,Q70UQ0,Q9NQX7,Q96G23,P50402,Q8N0U8,Q9Y450,Q9Y584,Q96N66,Q92896,O00264,O15031,Q9HD45,P53985,Q2TAA5,O15118,Q86Y82,Q96PC5,Q15904,Q8N5M9,P57105,Q8NHH9,P98172,O14975,P30825,Q7Z3C6,Q6N075,Q9UKU0,O75844,P51572,Q07065,Q6P4Q7,Q96JJ7,Q96TC7,Q9Y666,Q8TCT9,O75976,O96005,Q9Y6M7,P10586,Q96KA5,P48651,O95249,Q86Y39,Q99808,Q92734,Q16134,Q969M3,Q9NR28,Q16625,Q8TCJ2,Q5JTV8,O14936,Q15043,Q9Y5M8,Q8TB61,P56962,P33121,Q14108,Q9P0J0,Q6NUM9,Q14534,Q08722,Q9Y6C9,Q8IXM6,P37268,P35610,P35080,Q00765,P51648,P28288,P04439,Q9Y276,Q8TBA6,Q9H6H4,P16435,Q96SK2,Q8WVC6,Q8N1F7,Q14012,Q9BTV4,O15344,Q9Y4W6,Q99523,Q9BX67,Q8IWA4,P11717,O95470,Q07954 184 +Candidate cardiovascular disease genes 0.3865741906063448 0.3616663175653634 0.7176014002004587 0.9999999999970616 1.0 9 Q9UNN8 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..69c7a1f27f35f1030a7a2e25b0c618dfc000b613 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C3orf58", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPP", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHERP", "CHID1", "CHM", "CHMP1A", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG6", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPM1", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM89A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAGH", "HAT1", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LPP", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYRM7", "LYSMD3", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED24", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL44", "MRPL46", "MRPL47", "MRPL49", "MRPL50", "MRPL53", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NT5DC3", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POMGNT2", "PON2", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP2B", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX3", "SNX4", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLK2", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM160", "TMEM161A", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41B", "TMEM43", "TMEM65", "TMEM70", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS18", "VPS25", "VPS26A", "VPS26B", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS52", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFC3H1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC4", "ABCD3", "ACBD5", "ACSL1", "ACSL6", "AFG3L2", "AGTRAP", "AIFM1", "ALDH3A2", "ALG11", "ANKLE2", "APMAP", "ATG9A", "ATL2", "ATP13A1", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP7B", "BCAP31", "BCS1L", "C5orf15", "CAMK1", "CAMLG", "CASK", "CCDC134", "CD47", "CERS2", "CKAP4", "CLPTM1", "CLPTM1L", "CNNM4", "COA3", "COX2", "CPD", "CUTA", "CYB5B", "CYB5D2", "CYP51A1", "DCAKD", "DEGS1", "DHCR24", "DIABLO", "ECE1", "EFNB1", "EIF3L", "EMD", "ERGIC3", "ETFDH", "FAM177A1", "FAM8A1", "FDFT1", "FUCA2", "GALNT1", "GHITM", "GLG1", "GOLGA5", "GOLIM4", "GOSR1", "GPR107", "GPR108", "HBS1L", "HDGF", "HLA-A", "HM13", "HMOX2", "ICMT", "IGF2R", "IKBIP", "ITM2C", "JAGN1", "JAM3", "KDSR", "KIAA0319L", "KTN1", "LARP4B", "LBR", "LNPEP", "LRP1", "LRRC8C", "MAN2A1", "MBOAT7", "MCUR1", "MFN1", "MFSD5", "MIA2", "MID1", "MPV17L2", "MTCH2", "MTX1", "NAMPT", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFB3", "NENF", "NNT", "NPC1", "NRM", "NUCB1", "NUCB2", "NUP93", "OCLN", "OPA3", "OXA1L", "PEX14", "PEX3", "PFN2", "PGRMC1", "PGRMC2", "PLA2G15", "PLD3", "PLXNB2", "PON2", "POR", "PROCR", "PTDSS1", "PTPRF", "PXMP2", "REEP4", "REEP5", "RETSAT", "RMDN3", "RRM2", "RTN3", "RTN4", "SCARB1", "SCARB2", "SCCPDH", "SCPEP1", "SEC62", "SFXN2", "SGPL1", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A20", "SLC25A26", "SLC27A2", "SLC29A1", "SLC30A5", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SMDT1", "SOAT1", "SORT1", "SPNS1", "SQLE", "SRPRB", "SSR1", "STARD3NL", "STT3B", "STX12", "STX17", "STX18", "SURF4", "SYNJ2BP", "TAF15", "TAP2", "TFG", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM50", "TM9SF2", "TM9SF3", "TMEM126A", "TMEM160", "TMEM192", "TMEM199", "TMEM205", "TMEM209", "TMEM43", "TMX3", "TMX4", "TOMM22", "TOR1AIP1", "TRABD", "TRAM1", "TSPAN6", "UQCR10", "VANGL1", "VKORC1L1", "YIPF5", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6230a11c0dcba9c026b1606ca103977120de535d --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Peroxisomes", "1": "Golgi apparatus", "2": "Nuclear speckles", "3": "Centriolar satellite", "4": "Endoplasmic reticulum", "5": "Nuclear membrane"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..540963576b975887e21da686815499d1af773c88 --- /dev/null +++ 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+size 72146 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..158e371b7affb3150a9e87fbbd13cd66dda34b58 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3068, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 142.27272727272728 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..88b7cb43a1f9bdd109203f404f38898e39b741d6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C430/C430_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..10276a1b9af9eaa197231a3a277676e509f3aa9a --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Focal adhesion sites 0.4592808578031025 1.1014426551987038 0.2707040494416248 0.9999700893762076 0.9534849927793808 27 Q93052,P08183,O60888,Q9Y3B8 4 +Peroxisomes 0.4502979843689215 1.0799350745448884 0.2801710929506578 0.999980565814475 0.9534849927793808 17 Q9BY49,O15254,P40855,O75381,Q15067,P56589 6 +Golgi apparatus 0.3859712973381623 1.0379755774135184 0.2992814254206253 0.9999920027663244 0.9534849927793808 167 Q96C57,Q5VW38,Q15043,O00461,Q9UBU6,P80303,Q8TDW0,Q8IXU6,Q93050,Q8NEY8,Q9NPR9,Q8TAD4,Q8NC54,Q8N4Q0,Q8TD16,Q9HB40,Q8IZA0,Q8N6H7,Q6NT16,Q16706,P04439,A4D1U4,Q14004,Q8TBA6,O15439,O15260,Q5BKZ1,Q92896,A9UHW6,Q02818,Q9HD45,Q96GI7,P10586,Q6P179,Q08379,O15344,O15212,Q9H2V7,Q5VU43,Q969M3,Q9NWM8,Q9H3P7,Q99523,Q9BX67,Q86Y82 45 +Nuclear speckles 0.3506975285910481 0.9697265857009888 0.3321827950069287 0.9999983643103 0.9534849927793808 126 Q86VM9,Q9P275,Q9Y5S9,Q14139,O75600,P78332,Q96PK6,Q13123,Q08170,Q9NYF8,P82979,Q93050,P43490,Q15024,Q15233,O43290,Q9P2N5,Q03519,Q92733,Q14157,Q7Z4H7,Q6IQ49,Q86U42,O75934,O95400,Q9ULX6,Q9P013,Q14004,O75976,Q8IY18,P10412,Q9BU76,P02545,Q96SK2,Q53F19,Q12972,Q92841,P49756,P16104,O95453,Q9Y2W1,P98175,Q96RT1,Q12874,Q9H0E3,Q9Y2V7 46 +Centriolar satellite 0.4157556737655886 0.833595814822842 0.4045087848154949 0.9999999627705304 0.9534849927793808 24 Q9UBK9,Q86UY6,Q7Z4H7,O43169,P41208 5 +Endoplasmic reticulum 0.3569556243075573 0.4286622217316675 0.6681690571508869 1.0 1.0 194 Q8WUJ1,P21964,Q8NHH9,Q15043,Q16850,Q9H3G5,O75477,Q14257,Q9P2W9,Q03519,P37268,Q6UW68,P35610,P53609,P67809,Q00765,P51572,Q99956,Q96F07,Q9NQC3,P51648,P13674,Q70UQ0,Q96G23,Q8IV08,Q8TCT9,P50402,Q8N0U8,O15260,O96005,O00264,O43169,Q86XL3,Q96HY6,Q96KA5,O43852,P48651,Q92791,O95197,Q15293,P43307,Q13217,Q969M3,Q9Y680,Q96PC5,Q8TCJ2 46 +Nuclear membrane 0.3266401823007145 0.3155804110854908 0.7523210081002154 1.0 1.0 64 Q5JTV8,Q96G23,Q8IXM6,P50402,O75976,Q6UW68,O15260,Q8NFH5,P11802,P12270,Q9BW91,Q96SK2,Q14739,P20700,Q9BTX1,Q03252 16 +Kinetochore 0.6784083496412152 0.2390057783757354 0.8111011020820769 1.0 1.0 2 Q9BZD4 1 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eebae22f2f99fd49c4177aa82d0fbcad6807841a --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APC", "APEH", "APEX1", "API5", "APMAP", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARVCF", "ASCC1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATR", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAT1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf73", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C5orf15", "C5orf24", "C8orf33", "CAB39", "CABIN1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMLG", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5RAP3", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPF", "CENPI", "CENPP", "CENPV", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHCHD4", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD7", "CHD8", "CHID1", "CHM", "CHMP1A", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG6", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COQ5", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF16", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DPF2", "DPP3", "DPP9", "DPY19L3", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTNBP1", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELOA", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM50A", "FAM89A", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXK1", "FOXO3", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLB1", "GLCE", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2A1", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP2", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HGH1", "HGS", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS12", "INTS13", "INTS14", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "ISOC1", "ISOC2", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIN", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "L2HGDH", "LAMP2", "LAMTOR1", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCOR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LPP", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLAL1", "LYSMD3", "MACF1", "MAD2L1", "MAGED2", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBLAC2", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MESD", "METAP1", "METTL1", "METTL13", "METTL17", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIF4GD", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTF2", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYBBP1A", "MYCBP", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NFATC2IP", "NFKB2", "NFU1", "NGEF", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE1", "NSMCE2", "NSUN2", "NSUN5", "NT5DC1", "NT5DC3", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "OPTN", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDE8A", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGGT1B", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKB", "PI4K2A", "PIAS2", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QPRT", "QSOX2", "QTRT2", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAPGEF2", "RAPGEF6", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX1", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3PXD2B", "SHMT2", "SHOC2", "SHPK", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC5A6", "SLC6A15", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX2", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOC7", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8A", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMEM109", "TMEM126A", "TMEM161A", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM41B", "TMEM70", "TMOD3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM6", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIM4", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT2A", "TRMT61A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN6", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC37", "TTC38", "TTC4", "TTF2", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR77", "WDR82", "WIZ", "WNK1", "WTAP", "XAB2", "XIAP", "XPC", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBED4", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3HAV1", "ZCCHC3", "ZCCHC8", "ZFC3H1", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC4", "ACBD3", "ACOX1", "ACOX3", "AKAP8L", "ALDH3A2", "ANKLE2", "ARFGAP2", "ATL2", "ATP6V0A1", "BCAP31", "BCAS2", "BCLAF1", "BICD2", "C12orf43", "C1orf35", "C5orf15", "CALU", "CD2BP2", "CDK13", "CDK4", "CERS2", "CETN2", "CLPTM1", "CLPTM1L", "COG6", "COMT", "CPD", "CPVL", "CUTA", "CWC15", "CYB5B", "CYB5D2", "CYFIP2", "CYP51A1", "DDRGK1", "DDX17", "DNAJC3", "DUSP9", "EMD", "ERAP2", "ERBIN", "ERLIN1", "EXOSC7", "FAM89A", "FAM8A1", "FDFT1", "FKBP14", "FKBP7", "GCAT", "GLG1", "GOLGA2", "GOLGA5", "GOLIM4", "GPR107", "GPR108", "H2AFX", "HAUS6", "HIST1H1E", "HLA-A", "HM13", "IK", "IKBIP", "JAM3", "KIAA0319L", "KIAA1147", "LBR", "LMNA", "LMNB1", "LMNB2", "LPP", "LRRC8C", "MAN2A1", "MIA2", "MID1", "MIF4GD", "NAA40", "NAMPT", "NCBP3", "NDC1", "NONO", "NRM", "NUCB1", "NUCB2", "NUDT9", "NUF2", "NUP35", "P3H4", "P4HA1", "PABPN1", "PARN", "PDE4DIP", "PECR", "PEX14", "PEX19", "PEX3", "PFDN6", "PGGT1B", "PGRMC1", "PLD3", "PPHLN1", "PPP1R8", "PRCC", "PTDSS1", "PTPRF", "RBM10", "RBM14", "RBM25", "RBM27", "RBM6", "RBM8A", "RCN1", "RCN2", "REEP5", "REXO2", "RTN3", "RTN4", "SAP130", "SARNP", "SART1", "SCPEP1", "SDE2", "SF3A3", "SLC18B1", "SLC30A5", "SLC35F2", "SLC39A14", "SMC5", "SOAT1", "SORT1", "SPNS1", "SRSF4", "SSR1", "STT3B", "STX12", "STX18", "SURF4", "TAP2", "THRAP3", "TM9SF3", "TMEM205", "TMEM209", "TOR1AIP1", "TPR", "UBAP2L", "UBE4A", "USP36", "UXT", "VKORC1L1", "YBX1", "YIPF5", "ZADH2", "ZC3H18", "ZNF326"]} \ No newline at end of file