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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Mitochondrial long chain fatty acid betaoxidation 0.7003208892513707 2.348159039599084 0.0188664636452042 0.9999877959581378 0.6236392789864199 14 P42126,Q9BY49,P23786,Q16836,O43772 5
Endothelin pathways 0.8047466989206331 2.290513826818685 0.0219915479755119 0.9999981655361496 0.6236392789864199 8 P00403,P42892 2
Acquired partial lipodystrophy barraquersimons syndrome 0.8775710088148863 2.2249558292946663 0.0260842035326995 0.9999998480441205 0.6236392789864199 5 P02545,O60725,P49354,Q03252 4
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6398969645951363 2.1762919857343817 0.0295334344273501 0.9999999815301588 0.6236392789864199 16 O60725,O75844,P50402,P02545,P49354,P55209 6
Vitamin a and carotenoid metabolism 0.8465234745150451 2.099622794632606 0.0357620359674086 0.9999999995968836 0.6236392789864199 5 O94788 1
Pregnane x receptor pathway 0.8442506197076971 2.090380890819403 0.0365835980703854 0.9999999997570386 0.6236392789864199 5 O15439,P08183 2
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.9228044565504157 2.0899899695373554 0.0366187007446545 0.9999999997622404 0.6236392789864199 4 P07099 1
Mitochondrial complex iii assembly 0.6989551478637201 2.085811568558371 0.0369956950913572 0.9999999998115624 0.6236392789864199 11 Q5U5X0,Q6DKK2,P22695,Q9UDW1,O14949 5
Mrna processing 0.4088562450092465 2.067453388548489 0.0386914519875725 0.9999999999338536 0.6236392789864199 98 P84103,P23246,Q13242,Q15233,Q9UHI6,P55795,P61978,P08621,P67809,Q99729,Q86U42,Q07955,P52756,O95400,P22626,P09012,P31943,O75494,O43390,P35637,Q96I25,Q16629,P62995,P07910,Q9UKA9,P38159,P09651 27
Statin inhibition of cholesterol production 0.8344760039177224 2.0505325526615845 0.0403124905327636 0.9999999999757267 0.6236392789864199 5 P37268,P35610,Q14534,Q8WTV0 4
Influence of laminopathies on wnt signaling 0.6813892030796436 1.996565666715317 0.0458723856399214 0.9999999999992304 0.6487665969074607 11 O60725,O75844,P50402,P02545,P49354 5
Ketogenesis and ketolysis 0.8029022422943444 1.9298079754873896 0.0536306349316837 0.999999999999994 0.6560016353503835 6 P53985,O43772,P23786 3
Fatty acid betaoxidation 0.5708781941386433 1.907275676867531 0.0564848982004706 0.999999999999999 0.6560016353503835 21 P42126,Q9UKU0,P23786,Q16836,P33121,O43772 6
Sphingolipid metabolism integrated pathway 0.6924579911833769 1.8585614644713868 0.063089323556444 1.0 0.6560016353503835 9 Q06136,O15121 2
Sphingolipid metabolism overview 0.6924579911833769 1.8585614644713868 0.063089323556444 1.0 0.6560016353503835 9 Q06136,O15121 2
Familial partial lipodystrophy fpld 0.7323653432340742 1.7873948435237257 0.0738736944583098 1.0 0.6560016353503835 7 O60725,O75844,P02545,P49354,Q03252 5
Allograft rejection 0.6769623285112513 1.7832695412403758 0.0745424370743665 1.0 0.6560016353503835 9 Q9BY49,P08183 2
Sphingolipid metabolism in senescence 0.5936012197583053 1.7554659088165694 0.079179646987918 1.0 0.6560016353503835 14 Q96G23,Q06136,O15121,P17252,P05771 5
Genes related to primary cilium development based on crispr 0.6516510973528333 1.659138232362496 0.097087940726968 1.0 0.676117239080416 9 Q10713 1
Omega3 omega6 fatty acid synthesis 0.7328793254399256 1.634707403003374 0.1021103998552646 1.0 0.676117239080416 6 Q15067,O15254 2
Melatonin metabolism and effects 0.8037640999788264 1.6277389498935733 0.1035802504315115 1.0 0.676117239080416 4 P42892 1
Tryptophan metabolism 0.5587017042134941 1.6194057048992292 0.105360000182894 1.0 0.676122151482844 15 P35610,Q15392,Q16836,O94788 4
Proximal tubule transport 0.6051102936862947 1.599731216411441 0.1096582236217114 1.0 0.677424007972915 11 P08195,O15439,P08183,P36543 4
Constitutive androstane receptor pathway 0.7175980984157311 1.5620999850864046 0.1182644364149521 1.0 0.6777424675652055 5 P08183 1
Riboflavin and coq disorders 0.7828764450169862 1.544924400341226 0.1223645506576938 1.0 0.6777424675652055 4 Q16134,Q8NI60 2
Ccl18 signaling pathway 0.6102435949284806 1.5360552791847462 0.1245248231887683 1.0 0.6777424675652055 10 P00403 1
Striated muscle contraction pathway 0.7104146261834889 1.5314573203152244 0.1256564068550498 1.0 0.6777424675652055 5 O43707,P67936,P08670,P06753 4
Progeriaassociated lipodystrophy 0.6050511440275606 1.5093366734013067 0.13121276728956 1.0 0.6777424675652055 10 O60725,O75844,P02545,P49354,Q03252 5
Metabolism of spingolipids in er and golgi apparatus 0.7676473089373166 1.4843091929006251 0.1377269126097711 1.0 0.687477194035328 4 Q06136,O95470 2
Mecp2 and associated rett syndrome 0.50995766986601 1.3914320578193848 0.1640944490552582 1.0 0.735220760861711 16 P52597,P35637,P67809 3
Type i collagen synthesis in the context of osteogenesis imperfecta 0.5467954802894788 1.3777267396091586 0.1682876723333231 1.0 0.7404657582666216 12 Q32P28,Q96AY3,O75718,O15460,P13674 5
Gpr143 in melanocytes and retinal pigment epithelium cells 0.839029563786964 1.3540269228320778 0.1757277885032375 1.0 0.7424985974068844 3 P17252 1
Cholesterol biosynthesis with skeletal dysplasias 0.6687911951639143 1.3529448396228692 0.1760732530529538 1.0 0.7424985974068844 5 Q15392 1
Cytosine methylation 0.6620154299585651 1.3237693430678172 0.1855796606268975 1.0 0.7655161000859525 5 P48735 1
Alzheimers disease and mirna effects 0.3364354526881349 1.2821014521709433 0.1998070596296772 1.0 0.7808806989328317 82 P28070,P28072,P49721,O95197,P45880,P20618,P21796,Q99436 8
Alzheimers disease 0.3419808053163695 1.2820607860051636 0.1998213236326438 1.0 0.7808806989328317 80 P28070,P28072,P49721,O95197,P45880,P20618,P21796,Q99436 8
Sarscov2 and covid19 pathway 0.8058924054505852 1.2301119217949497 0.2186551962880241 1.0 0.7982581255936555 3 Q8WTV0 1
Metapathway biotransformation phase i and ii 0.4684691608575222 1.2272684970831131 0.2197216919738993 1.0 0.7982581255936555 21 P07099,Q7LGA3,Q86UY6,Q16850 4
Amyotrophic lateral sclerosis als 0.5440033816885943 1.1923678956060109 0.233117022865025 1.0 0.7990044265868343 10 P20339,P07197,Q08209,Q9UER7,O96008,P07196,P04637 7
Tumor suppressor activity of smarcb1 0.483118380236275 1.1641849487379512 0.2443490684818317 1.0 0.7990044265868343 15 Q92925,P84243,P11802,Q8TAQ2,Q92785,Q969G3 6
Calcium regulation in cardiac cells 0.4701603903385151 1.163552879998952 0.2446052564384988 1.0 0.7990044265868343 29 Q9UBI6,P63104,P63218,P16615,Q9Y3B8,P17252,P08133,P05771,Q14012,P13861 10
Cholesterol metabolism with bloch and kandutschrussell pathways 0.4577308691030596 1.1547990910434391 0.2481727094254151 1.0 0.7990044265868343 21 Q15392,Q15126,P37268,Q9BWD1,Q16850,P33121,Q14534 7
Sleep regulation 0.6840482956381801 1.1498012350763205 0.2502257464443742 1.0 0.7990044265868343 4 P00813 1
Myometrial relaxation and contraction pathways 0.4575861974849966 1.1410304774595084 0.2538572403047077 1.0 0.7990044265868343 22 Q9UBI6,P63104,P63218,P16615,Q9Y3B8,P17252,P05771,P13861 8
Initiation of transcription and translation elongation at the hiv1 ltr 0.6141448669962442 1.1211248983396218 0.2622347017717545 1.0 0.7990044265868343 6 Q9H3P2,Q8IXH7,Q08209 3
Mevalonate pathway 0.6709138556445999 1.097320410118247 0.2725013518077981 1.0 0.8013158563060994 4 Q9BWD1 1
Drug induction of bile acid pathway 0.9761904761904756 1.0909496141293684 0.2752950540623333 1.0 0.8016551213530024 2 P08183 1
Cellular proteostasis 0.6072249205867584 1.087647040371296 0.276750955713831 1.0 0.8019027692391006 5 O15212 1
Gastric cancer network 1 0.5207281388474787 1.0708836038944447 0.2842217690507929 1.0 0.8039943750512479 10 P84243 1
Vitamin d receptor pathway 0.5064980422703064 1.070842095346573 0.2842404356241785 1.0 0.8039943750512479 11 Q96KA5,P08183 2
Mevalonate arm of cholesterol biosynthesis pathway 0.5307369460996505 1.052186165335283 0.2927141455485829 1.0 0.8163014199805552 9 P37268,Q9BWD1,Q15126 3
Dopamine metabolism 0.7463854691704485 1.0090875170889304 0.3129326640605208 1.0 0.8398260463953421 3 P17252 1
Ppar signaling pathway 0.4454665006223072 0.989133972157312 0.322597598178183 1.0 0.8413527450788771 16 Q9UKU0,P23786,O15254,O14975,Q15067 5
Preimplantation embryo 0.5575766140493641 0.9889161338789166 0.3227041760932811 1.0 0.8413527450788771 7 Q99729,Q92945 2
Common pathways underlying drug addiction 0.5296379926764454 0.9826483175675336 0.3257805552936517 1.0 0.8413527450788771 8 P17252 1
Nanomaterial induced apoptosis 0.7301580733641085 0.949554629520836 0.3423386012978209 1.0 0.8437405647282684 3 O95831 1
Sudden infant death syndrome sids susceptibility pathways 0.4341754183533331 0.9275510506872352 0.3536404989078565 1.0 0.8437405647282684 27 P42892,P10809,P67809 3
Oxidation by cytochrome p450 0.5627601690127726 0.8988518220289718 0.3687315928178298 1.0 0.8598363987097822 6 O43169,Q16850 2
Histone modifications 0.5091189608424465 0.882440518940696 0.3775386322464373 1.0 0.8632273820152369 8 Q01105,P84243 2
Heme biosynthesis 0.558214402261777 0.878457633925591 0.3796954193138639 1.0 0.8635063594044091 5 P22830,P50336 2
Wnt signaling pathway 0.4671295008005969 0.8598690973608097 0.3898612048771426 1.0 0.8720715973837397 11 P17252 1
Ethanol effects on histone modifications 0.4792955322568517 0.8558893544594385 0.3920589838871855 1.0 0.8722211102209295 10 O94788 1
Thermogenesis 0.4240321631768597 0.8489433750551629 0.3959128015492172 1.0 0.872924323894688 28 Q9UKU0,P23786,P17252,Q969G3,O43772 5
Kennedy pathway from sphingolipids 0.6985318107667069 0.8350705999803895 0.4036779589110859 1.0 0.8751266700481206 3 O95470,P48651 2
Mitochondrial complex i assembly model oxphos system 0.4190168296797295 0.8235749676017942 0.4101811042514502 1.0 0.880015553725513 27 Q8N183,O96000,O43676,Q9Y6M9,P03915,Q96CU9 6
Male infertility 0.4001311344064156 0.7999847677396876 0.4237196225348489 1.0 0.8860025767830539 19 P08183,P41440 2
Fatty acid transporters 0.5359066375680637 0.7850009943693157 0.4324529855850922 1.0 0.8860025767830539 5 Q9UKU0 1
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4372147933833599 0.7698547720982918 0.4413860451697791 1.0 0.8860025767830539 12 P10809 1
Circadian rhythm genes 0.4164242291179578 0.751057379980375 0.4526181239369693 1.0 0.8932065302942186 39 Q15233,Q9BWF3,P00813,Q03164,P54802,P11802,Q9Y2W1,P23246,P43490 9
Corticotropinreleasing hormone signaling pathway 0.3859413739116606 0.7243452125906167 0.4688538262508941 1.0 0.9012918213366702 18 P42892,P17252 2
7oxoc and 7betahc pathways 0.4618288606364086 0.7081286788065873 0.4788653515135692 1.0 0.9030032342827308 9 P34913,O15118 2
Nuclear receptors in lipid metabolism and toxicity 0.8548597521200151 0.693440235094155 0.4880333196787738 1.0 0.9090665518275418 2 P08183 1
Sphingolipid pathway 0.4573597702516556 0.6863616966594835 0.4924850521178114 1.0 0.9113274796198754 9 Q06136 1
Familial hyperlipidemia type 3 0.833659491193725 0.6288163310978228 0.5294693071379779 1.0 0.9377177376413351 2 Q8WTV0 1
Eicosanoid metabolism via cyclooxygenases cox 0.494604943775317 0.6139598515491538 0.539241858018539 1.0 0.9393245268710032 6 Q15067,Q8N8N7 2
Adipogenesis 0.3937811134358377 0.5967307228436464 0.5506871771128132 1.0 0.9421995730536854 14 P43490,O75844 2
Eicosanoid metabolism via lipooxygenases lox 0.489826517125187 0.5947722646166702 0.5519957094657955 1.0 0.9421995730536854 6 Q15067,Q8N8N7 2
Glycosaminoglycan degradation 0.4846066570693588 0.5739728900094055 0.565986146708362 1.0 0.9450295746024184 6 P54802,P15586,P16278 3
Cholesterol biosynthesis pathway 0.4053830965377139 0.5415481012845457 0.5881298526056442 1.0 0.9450295746024184 11 Q16850,Q14534,Q15126 3
Spinal cord injury 0.361429224151782 0.5223753351982761 0.6014090256253661 1.0 0.9472800100559032 21 P11802,P17252,P08670,Q9NQC3 4
Kisspeptinkisspeptin receptor system in the ovary 0.4301995555929204 0.5105237124600372 0.6096846063633801 1.0 0.9472800100559032 8 P17252 1
Pdgfrbeta pathway 0.4173314527658409 0.4971189281499485 0.6191051875212903 1.0 0.9472800100559032 9 P17252 1
Ketone bodies synthesis and degradation 0.5974394572629739 0.493606966652905 0.6215837797447654 1.0 0.9472800100559032 3 P35610 1
Prostaglandin synthesis and regulation 0.4427691819102519 0.481967619932574 0.6298289486451207 1.0 0.9472800100559032 7 O15439,P08133 2
Proteasome degradation 0.3787452794412788 0.4816218225798539 0.6300746209329482 1.0 0.9472800100559032 42 P49721,P28070,P28072,P20618 4
Effect of progerin on genes involved in hutchinsongilford progeria syndrome 0.3770173272433578 0.4795885259989749 0.6315200067039355 1.0 0.9472800100559032 13 Q12873,P83916,P84243,Q13185,P45973,P04637 6
Arachidonate epoxygenase epoxide hydrolase 0.7703848662752648 0.4496245753727098 0.6529811648380823 1.0 0.9577057084291876 2 P34913 1
Dna damage response 0.3456740075564172 0.4423049777372276 0.6582685293861157 1.0 0.9597693020253634 20 Q9Y3B8 1
Zinc homeostasis 0.5741761599449365 0.4233362627057747 0.6720499405072435 1.0 0.9679904693954088 3 Q8TAD4 1
Mrna protein and metabolite inducation pathway by cyclosporin a 0.7570123939986892 0.4149149435573837 0.6782041699537908 1.0 0.968954597687376 2 P08195 1
Mirna regulation of dna damage response 0.336927968874266 0.3767496538484822 0.7063596587160625 1.0 0.9751948366499292 21 Q9Y3B8 1
Mirnas involved in dna damage response 0.7407045009784723 0.3743215477086267 0.7081651026887599 1.0 0.9751948366499292 2 P16104 1
Mirna regulation of p53 pathway in prostate cancer 0.7407045009784687 0.3743215477086187 0.7081651026887659 1.0 0.9751948366499292 2 O14681 1
Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.383040434572359 0.3468427331878464 0.728709471161419 1.0 0.9776898443411344 9 P31943,P62070,P20339,O14964 4
Ovarian infertility 0.7279843444226877 0.3440635827889252 0.7307984695075147 1.0 0.9776898443411344 2 P11802 1
G protein signaling pathways 0.3220511255053538 0.338978446061519 0.734625967451779 1.0 0.980601853182824 18 O43823,Q9UBI6,P63218,P17252,P05771,P13861 6
Bladder cancer 0.3988945188380212 0.3122634365713039 0.754840325076215 1.0 0.9923993139062278 7 O00459,P11802 2
Joubert syndrome 0.3280557810187037 0.3092080544004981 0.7571632674015258 1.0 0.9923993139062278 16 Q10713 1
Erbb signaling pathway 0.3137975744795596 0.2947033028151403 0.7682205398969226 1.0 1.0 18 P05771,P17252 2
Cohesin complex cornelia de lange syndrome 0.3287494223491298 0.2886973346984522 0.7728130025009898 1.0 1.0 15 Q9Y6X3,Q8N3U4,P53350,Q96GD4 4
Extracellular vesiclemediated signaling in recipient cells 0.4453559003863809 0.288013166077499 0.7733366604297096 1.0 1.0 4 Q9NWH9 1
Dna mismatch repair 0.3186846539781635 0.2637463216490234 0.7919753993727552 1.0 1.0 16 P41440 1
Eicosanoid synthesis 0.6865622961513277 0.2548041066175835 0.798874403322539 1.0 1.0 2 P09960 1
Folate metabolism 0.3158124806751901 0.2298484901347499 0.818209503594092 1.0 1.0 15 Q8WTV0 1
Orexin receptor pathway 0.3048641430994237 0.2199556120501734 0.8259057245413712 1.0 1.0 20 O00459,Q9H4L5,P50336,Q8TDW0,P17252,P31350 6
Nanoparticlemediated activation of receptor signaling 0.3804702808621829 0.2114579152262712 0.8325299684576588 1.0 1.0 6 Q02750,P05556,P28482,P36507,P62993 5
Oxysterols derived from cholesterol 0.3549104521777434 0.2057000950819588 0.8370251842830265 1.0 1.0 8 P34913 1
Il18 signaling pathway 0.3270364003336145 0.2032214161795261 0.8389619743912999 1.0 1.0 57 Q9UMR5,Q9NQX7,Q92733,Q16836,Q9Y6M7,Q8N6H7,P17252,Q13011,P51858,P05771,Q03252 11
Egfegfr signaling pathway 0.3338576084538963 0.1892160432395468 0.8499234941014089 1.0 1.0 42 Q92783,O00459,P46108,P00403,P53680,O14964,P17252,Q9P0J0,P05771 9
Wnt signaling pathway and pluripotency 0.2984437676871092 0.1576151235761581 0.8747600856493254 1.0 1.0 15 P30154,Q9H0H5,P17252,P05771,P04637 5
Metastatic brain tumor 0.6291585127201462 0.1567157959800231 0.8754688375184869 1.0 1.0 2 P04637 1
Hippo signaling regulation pathways 0.2885239220612305 0.1499090649356421 0.8808363597554096 1.0 1.0 17 P17252 1
Agerage pathway 0.2961082892836286 0.1485463686737682 0.8819115949233913 1.0 1.0 15 P17252 1
Pathways affected in adenoid cystic carcinoma 0.2937515295344555 0.1395574275517968 0.8890096792422617 1.0 1.0 15 P10412,P46100,Q96RT1,Q9UBU8,Q99417,Q969G3 6
Ferroptosis 0.2977362997171137 0.1362905176170666 0.8915916197837177 1.0 1.0 24 Q9UKU0,P37268,Q15043,P16435,P45880,P33121 6
Ectoderm differentiation 0.2804183521555753 0.1353449849295566 0.8923391194353174 1.0 1.0 18 P17480,O15439,Q9HBH5 3
Praderwilli and angelman syndrome 0.3406604445431547 0.1286154930820197 0.8976619064270126 1.0 1.0 5 P11802 1
Nephrotic syndrome 0.2955827473550503 0.1195929827367258 0.9048055787916434 1.0 1.0 12 O43707,O75844,Q9BT22,P02545,Q14108 5
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.5988258317025312 0.1173673662255872 0.9065689432863197 1.0 1.0 2 P09601 1
Gdnfret signaling axis 0.4313213703099492 0.1073585508999746 0.9145045359900428 1.0 1.0 3 P35222,Q9BW83 2
Development of ureteric collection system 0.4313213703099375 0.1073585508999587 0.9145045359900554 1.0 1.0 3 P35222,P05556 2
Gpr40 pathway 0.5779517286366456 0.0951534143760219 0.924192971965117 1.0 1.0 2 P29992 1
Neuroinflammation and glutamatergic signaling 0.284612596053044 0.0913582929888479 0.9272079004850348 1.0 1.0 23 Q8TDW0,P17252 2
Kit receptor signaling pathway 0.2706054309424966 0.0830439362975606 0.933816604128378 1.0 1.0 19 P05771,P17252 2
Physicochemical features and toxicityassociated pathways 0.2716273333463098 0.0723304966934835 0.9423388953984008 1.0 1.0 16 P07197,P35080,Q14012 3
Hepatitis b infection 0.2739639093505159 0.0721660548383939 0.9424697590276356 1.0 1.0 21 P05771,P17252 2
Ciliopathies 0.275028380151776 0.0671299297894027 0.9464782671034886 1.0 1.0 14 O43924,Q9UBB4,P49454,Q10713 4
Arrhythmogenic right ventricular cardiomyopathy 0.2765576071104292 0.066583375314338 0.9469133809493696 1.0 1.0 13 Q14118,O43707,P35221,P50402,P35222,P02545,P16615,Q14126 8
Ciliary landscape 0.2550079886964344 0.06029226751193 0.9519228603754571 1.0 1.0 97 O95400,P16278,Q9HDC9,O43805,P10619,P84243,P07197,Q96PK6,Q13868,Q9Y4W6,O95721,P55081,Q15024,Q9UPT5,P08670,O15173 16
Wnt signaling 0.2690108961546444 0.0555403700858837 0.9557079688898384 1.0 1.0 15 P17252 1
Notch signaling 0.3699836867862996 0.0432469299647465 0.9655046953578736 1.0 1.0 3 Q92542,P56545 2
Fas ligand pathway and stress induction of heat shock proteins 0.264042170811154 0.0362071866755351 0.9711171556100342 1.0 1.0 14 P02545,Q03252 2
Angiogenesis 0.481735159817337 0.0360044654418762 0.971278798356674 1.0 1.0 2 P19174 1
Unfolded protein response 0.3487765089722697 0.0299210451496101 0.9761300217602032 1.0 1.0 3 Q9Y3I0,P04637 2
Interactions between loxl4 and oxidative stress pathway 0.2924281984334258 0.0253109772290758 0.9798069181745022 1.0 1.0 4 Q9BQ95,Q96EB6,Q8TAG9 3
Ptf1a related regulatory pathway 0.4044357469014957 0.0219849557052251 0.9824599562466688 1.0 1.0 2 P35222 1
22q112 copy number variation syndrome 0.2853832059219151 0.0189301305518784 0.984896843139708 1.0 1.0 31 Q9BW71,P21964,Q9NQ50,P45973,O94788,Q92973,O95721,Q9NQC3 8
Small cell lung cancer 0.2883712217689211 0.0167654775051182 0.986623710984422 1.0 1.0 8 O00459,P11802 2
Endoplasmic reticulum stress response in coronavirus infection 0.2786683066930002 0.0089711073292696 0.9928421879798324 1.0 1.0 6 O14974 1