Charley Brewster (William Ragsdale) finds out his charming next door neighbor, Jerry Dandridge (Chris Sarandon) is a bloodthirsty vampire who is feasting off the women of his neighborhood. In desperate need of help, he enlists the aids of his nerdy friend, Evil Ed (Stephen Geoffreys), his whiny girlfriend Amy (Amanda Bearse) and an out of work actor, Peter Vincent (Roddy McDowell) who plays "The Great Vampire Killer" on Primetime. Charley's problem is that no one believes him and his time is running out since Jerry is looking for his first opportunity to silence the snooping teenager for good.