Resident Evil: Apocalypse begins where the first film left off as Raccoon City has become a sweltering pot hole for T-virus infected zombies that seek human flesh to devour.  People seek refuge outside the city as the Umbrella Corporation, which is responsible for the mishap, has risen walls around the city in order to contain the virus within the city.  When it becomes apparent that the T-virus has reached the outer wall the Umbrella Corporation shuts down the passageway out as the remaining people within the city are left to fend for themselves.  One of these people, Alice (Milla Jovovich), has just awakened inside a hospital where she is attached to several different machines that monitored her health, and once again she has to fight for survival.