Titania Hardie has written a mysterious book that ties together the lives of two people, an immunologist, Dr. Alexander Stafford and his patient, Lucy King in unimaginable ways which eventually leads to romance. Their strong feelings of attraction are mixed in with complicated matters that relate back approximately 400 years to one of Dr. Stafford's ancestors, Dr. John Dee who was a close confidant and advisor to Queen Elizabeth. Dr. John Dee was a mathematician and an alchemist, who also invested much of his time studying esoteric and religious matters, including how to communicate with angels. He left two keys which would unlock boxes that contained puzzling documents which were entrusted to Dr. Stafford's youngest brother, Will. The keys were supposed to be passed on to the next female in line of succession but because Mrs. Stafford had no daughters, she entrusted this family secret to Will. Will was a free-lance photographer who had travelled to dangerous areas of the world,  hot posts where revolution and famine struck. After discovering the documents entrusted to him, Will went to Chartres Cathedral in France to walk the labyrinth and experience some of what his ancestor had written about. After returning to his home in the UK, he met a tragic and unexpected death on his motorcycle after crossing a bridge not far from his destination.