Just bought the game and played it for the first time yesterday with 4 players.  Good game to get the wives involved that that isn't too in depth in terms of multiple levels of strategy that scare away casual players.  The destination tickets add the variety to keep it fresh each time so that it's not always a race to get the 6 space routes.  The lack of dice help to keep chance (luck) to a minimum other than the rail cards that you draw.  Highly recommended.