We have tried a few different treats to help our pup with car sickness but either they didn't really work well or she didn't like them even if we mixed with her favorite food. These were really a lifesaver! As we prepared for a 1500-mile move in a U-Haul truck these were our last hope and thank goodness they work like a charm! Plus, she LOVES them and will even beg for them! During our 4 days crammed in the cab of our U-Haul she stayed can and relaxed and did not throw up at all... Not once! And that is great since any car ride over 20 minutes almost always resulted in her throwing up. We did use this in combination with a "Motion Sickness for Dogs" oil blend but there have been times we have used these treats without the oil and she has still done great. We will ALWAYS have these on hand!!!