As a minister, I study my Bible a lot.  I have a Thomson Chain Reference Bible which has pretty thin paper, so as to get so much info into a Bible you can carry.  I use highlighters very often, and this set is the only one I have found that will not "bleed" through.  The darker colors can be seen vaguely from the other side but do not "bleed".  Therefore, I simply make a vertical line on the left edge of a passage to organize, then highlight with the yellow to emphasize.  It works perfectly for me, and I would not only recommend it, but would make it almost mandatory for one who studies the Bible extensively.