I wash my face in the shower every morning.  I want to wash it every night, as well, but I dislike the splashing-water-in-my-face thing.  What's nice about Purete Thermale is that it doesn't need to be washed off.  Now, I can't vouch for how well it removes makeup because I don't wear any, but it does refresh my skin and adds a bit of moisture.  It doesn't dry like alcohol.  So far, no negative effects.  I would consider it my favorite facial cleanser to date.