I've bought several of the NIA skin care products; I bought this product from a medi spa where these products were really being pushed. I applied it exactly as directed and a few hours later broke out in pus-filled hives to all areas applied to...decolletage & throat,hands,forearms,neck and lower face. Now you may think...maybe it was something else that made the hives pop up? ...but the thing was you could actually see exactly where my hands & fingers had applied it to my skin and it happened 2 x's, the first time I was not sure it was this product,Sun Damage Repair Decolletage & Hands...but you could see the trail of where my hand & fingers had applied it...all red w/ small pustule-like bumps/hives...it left brown spots after healing. It left my skin damaged w/ brown spots where the pustules/hives had been...now I have to do TCA peels to remove the brown scarring I was left with. I will not use this again and I'm using up other NIA24 products and going back to exclusively to Perricone. I am ok with some of the other NIA24 products but they do seem to contain high amounts of waxy substances that leave a residue on my facial skin.