Embeti Manjusha1*, B. Kumar2
1PG Research Scholar, Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Nellore, A.P.
2Professor, Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Nellore, A.P.
A B S T R A C T
Recent studies have shown that dry eye is an inflammatory disease that has many features in common with autoimmune disease (2, 3, e1). Stress to the ocular surface (environmental factors, infection, endogenous stress, antigens, genetic factors) is postulated as the pathogenetic triggering mechanism. This is a prospective study was performed for a period of 6 months. The study was conducted in Ophthalmology department in a tertiary care hospital. A written informed consent form was obtained from the study patients. A sample size of 165 patients was enrolled in the study. Antibiotics were the most commonly prescribed ophthalmic drugs. Drug dosages, duration of therapy, strength and frequency of administration were incompletely and inadequately written in the prescription. In our study the most frequently prescribed ophthalmic drugs were antibiotics. The number of drugs per prescription and prescribing by generic names were also not in line with the WHO recommendation. We suggest that prescribers should strictly adhere to the WHO recommendations when to prescribe any of ophthalmic medications in order to promote rational use of drugs in such patients. A positive approach should be inculcated in the ophthalmologist for prescribing non-proprietary drugs preferentially from EDL.
Keywords: DNA vaccine immunogenicity, microbes, human body, transgene expression, synthetic plasmid.