7
Example 6 7
Predict the order of reactivity of the following
compounds in SN1 and SN2 reactions:
(i) The four isomeric bromobutanes
(ii) C6H5CH2Br, C6H5CH(C6H5)Br, C6H5CH(CH3)Br, C6H5C(CH3)(C6H5)Br
For a given alkyl group, the reactivity of the halide, R-X, follows the same order in both the
mechanisms R–I> R–Br>R–Cl>>R–F Rationalised 2023-24
175 Haloalkanes and Haloarenes
(c) Stereochemical aspects of nucleophilic substitution reactions
In order to understand the stereochemical aspects of substitution
reactions, we need to learn some basic stereochemical principles
and notations (optical activity, chirality, retention, inversion,
racemisation, etc )