Aromatic primary amines cannot be prepared by this method
because aryl halides do not undergo nucleophilic substitution with
the anion formed by phthalimide 6 Hoffmann bromamide degradation reaction
Hoffmann developed a method for preparation of primary amines by
treating an amide with bromine in an aqueous or ethanolic solution
of sodium hydroxide In this degradation reaction, migration of an
alkyl or aryl group takes place from carbonyl carbon of the amide
to the nitrogen atom