Rationalised 2023-24
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Chemistry
(iii) Retention: Retention of configuration is the preservation of the spatial
arrangement of bonds to an asymmetric centre during a chemical
reaction or transformation In general, if during a reaction, no bond to the stereocentre is broken,
the product will have the same general configuration of groups
around the stereocentre as that of reactant Such a reaction is said
to proceed with retention of the configuration Consider as an
example, the reaction that takes place when (–)-2-methylbutan-1-ol
is heated with concentrated hydrochloric acid