Kerry Reeves died two days after being shot in Abingdon on 3 November.
Billy Johnson, 20, from Ripon Court, Corby, Northamptonshire, and Charles Noble, 20, from Kempton Avenue, Northolt, Ealing, have both been charged with her murder.
They appeared at Oxford Magistrates' Court and will next appear at Oxford Crown Court on Monday.
Ms Reeves, 26, was found in Thornhill Walk. She was taken to the John Radcliffe Hospital in a critical condition where she later died.
A post-mortem examination was carried out on Monday, where the preliminary cause of death was given as a gunshot wound to the head.
Two men have appeared in court charged with the murder of a woman who was shot in the head in Oxfordshire.