Two men, aged 23 and 24, had a noxious substance thrown over them at 19:00 BST on Tuesday on Roman Road, Bethnal Green, east London.
Rahad Hussain, 23, has been charged with wounding with intent to do grievous bodily harm and possession of an offensive weapon, namely acid.
He was remanded in custody when he appeared at Thames Magistrates' Court.
Mr Hussain, of no fixed address,  gave no indication of a plea.
He is due to appear at Snaresbrook Crown Court on 29 August.
A man has appeared in court over an acid attack that left two people with "life-changing" injuries.