The builder said it would construct 139 homes at Duddingston Park South, Duddingston, and 165 at Newcraighall Village.
Barratt Homes will also build a total of 102 affordable homes between the two developments.
Newcraighall Village and Duddingston Park South are both set to launch later this year.
Anne Ross, sales director at Barratt Homes for the East of Scotland, said: "2014 has been buoyant year for new homes sales and we are pleased to be launching these two new developments in the Edinburgh area, to allow us to keep up with demand.
"With a wide selection of modern homes on offer and in sought-after locations, we hope these developments will be extremely popular."
Barratt Homes has confirmed it is pressing ahead with plans to build 400 new homes in the east of Scotland.