Leah Kerry was found unconscious at about 04:50 BST on Saturday at Bakers Park in Newton Abbot, Devon.
Jacob Khanlarian from Newton Abbot, was charged with two counts of intent to supply a class A drug and one of intent to supply a class B substance.
The 20-year-old entered no plea and was remanded in custody by Plymouth magistrates.
He will appear before Exeter Crown Court on 10 August.
More on the drug-related death and other Devon news
It is believed Leah, who was not from the area, suffered an adverse reaction from the substance. She died in Torbay Hospital.
Two other girls believed to have taken the same substance were also taken to hospital over the weekend as a precaution, but have since been released.
Det Supt Ken Lamont said: "With NPS (New Psychoactive Substances) no-one knows what's in them and that's why they are so dangerous.
"Time and time again we hear of people paying the ultimate price for this.
"It's not worth experimenting with your life."
Last year Totnes teenager Nathan Wood died after after taking the psychoactive drug N-Bomb.
Police called on parents to "speak to your children about the dangers of drugs and legal highs".
A man has been charged following the death of 15-year-old girl suspected of taking drugs.