Raymond Russell, 34, was charged with being concerned in the supply of a controlled drug to another person and also drug possession.
He appeared in private at Jedburgh Sheriff Court where he made no plea or declaration and his case was continued.
Russell was released on bail pending his next court appearance.
He was one of two men arrested and charged following Operation Archerfish on Thursday.
Eight houses in Galashiels, Hawick, Kelso and Selkirk were searched during the investigation of people suspected of being involved in the sale of drugs.
A total of Â£1,200 was seized, as well as drugs with a street value in the region of Â£3,750.
Police Scotland say they are also looking for another man in connection with a cannabis cultivation.
A Galashiels man has appeared in court following a major drugs operation involving 100 police officers in the Borders.