UC4NH4O2CH2CHC5H5NCO2(C4H6O)2 crystallizes in the orthorhombic P2_12_12_1 space group. The structure is zero-dimensional and consists of four 02329_fluka molecules; four 02329_fluka molecules; four 2,2,3,3-tetramethylbutanoic acid molecules; four formic acid molecules; four pyridine molecules; and four UC4NH4O2 clusters. In each UC4NH4O2 cluster, U(1) is bonded in a distorted linear geometry to one N(1), one O(1), and one O(2) atom. The U(1)-N(1) bond length is 2.57 Å. The U(1)-O(1) bond length is 1.82 Å. The U(1)-O(2) bond length is 1.82 Å. There are four inequivalent C sites. In the first C site, C(11) is bonded in a distorted bent 120 degrees geometry to one N(1) and one H(15) atom. The C(11)-N(1) bond length is 1.35 Å. The C(11)-H(15) bond length is 1.09 Å. In the second C site, C(13) is bonded in a distorted single-bond geometry to one C(14) and one H(17) atom. The C(13)-C(14) bond length is 1.40 Å. The C(13)-H(17) bond length is 1.09 Å. In the third C site, C(14) is bonded in a distorted trigonal planar geometry to one C(13), one C(15), and one H(18) atom. The C(14)-C(15) bond length is 1.39 Å. The C(14)-H(18) bond length is 1.09 Å. In the fourth C site, C(15) is bonded in a distorted bent 120 degrees geometry to one C(14), one N(1), and one H(19) atom. The C(15)-N(1) bond length is 1.35 Å. The C(15)-H(19) bond length is 1.09 Å. N(1) is bonded in a distorted trigonal planar geometry to one U(1), one C(11), and one C(15) atom. There are four inequivalent H sites. In the first H site, H(17) is bonded in a single-bond geometry to one C(13) atom. In the second H site, H(18) is bonded in a single-bond geometry to one C(14) atom. In the third H site, H(19) is bonded in a single-bond geometry to one C(15) atom. In the fourth H site, H(15) is bonded in a single-bond geometry to one C(11) atom. There are two inequivalent O sites. In the first O site, O(2) is bonded in a single-bond geometry to one U(1) atom. In the second O site, O(1) is bonded in a single-bond geometry to one U(1) atom. Linkers: 4 CC1(C)[C@@H](C([O])=O)CC[C@@]1(C)C([O])=O. Metal clusters: 4 [U]. The MOF has largest included sphere 6.05 A, density 1.53 g/cm3, surface area 3775.55 m2/g, accessible volume 0.25 cm3/g