Cd2C5N2H6O4BrCl3 crystallizes in the orthorhombic C222_1 space group. Cd(1) is bonded to one N(1), one O(1), one O(2), one Cl(2), and two equivalent Cl(1) atoms to form corner-sharing CdNCl3O2 octahedra. The corner-sharing octahedral tilt angles range from 62-69°. The Cd(1)-N(1) bond length is 2.43 Å. The Cd(1)-O(1) bond length is 2.37 Å. The Cd(1)-O(2) bond length is 2.37 Å. The Cd(1)-Cl(2) bond length is 2.58 Å. There is one shorter (2.56 Å) and one longer (2.68 Å) Cd(1)-Cl(1) bond length. There are four inequivalent C sites. In the first C site, C(1) is bonded in a distorted trigonal planar geometry to one C(2), one N(1), and one H(1) atom. The C(1)-C(2) bond length is 1.40 Å. The C(1)-N(1) bond length is 1.34 Å. The C(1)-H(1) bond length is 1.09 Å. In the second C site, C(2) is bonded in a trigonal planar geometry to two equivalent C(1) and one Br(1) atom. The C(2)-Br(1) bond length is 1.88 Å. In the third C site, C(3) is bonded in a distorted trigonal planar geometry to two equivalent N(1) atoms. Both C(3)-N(1) bond lengths are 1.34 Å. In the fourth C site, C(4) is bonded in a distorted bent 120 degrees geometry to two equivalent O(1) atoms. Both C(4)-O(1) bond lengths are 1.27 Å. N(1) is bonded in a distorted trigonal planar geometry to one Cd(1), one C(1), and one C(3) atom. There are three inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(1) atom. In the second H site, H(2) is bonded in a distorted single-bond geometry to one O(1) and one O(2) atom. The H(2)-O(1) bond length is 1.69 Å. The H(2)-O(2) bond length is 1.00 Å. In the third H site, H(3) is bonded in a single-bond geometry to one O(2) atom. The H(3)-O(2) bond length is 0.99 Å. There are two inequivalent O sites. In the first O site, O(1) is bonded in a distorted trigonal planar geometry to one Cd(1), one C(4), and one H(2) atom. In the second O site, O(2) is bonded in a distorted water-like geometry to one Cd(1), one H(2), and one H(3) atom. Br(1) is bonded in a single-bond geometry to one C(2) atom. There are two inequivalent Cl sites. In the first Cl site, Cl(1) is bonded in a distorted bent 120 degrees geometry to two equivalent Cd(1) atoms. In the second Cl site, Cl(2) is bonded in a water-like geometry to two equivalent Cd(1) atoms. Linkers: 2 [O]C(=O)c1ncc(Br)cn1. Metal clusters: 4 [Cd]. The MOF has largest included sphere 1.79 A, density 2.87 g/cm3, surface area 2647.00 m2/g, accessible volume 0.08 cm3/g