Ru6CoC18H12(NO4)6 crystallizes in the cubic Im-3m space group. The structure consists of a Ru6CoC18H12(NO4)6 framework. Ru(1) is bonded in a distorted square pyramidal geometry to one N(1) and four equivalent O(1) atoms. The Ru(1)-N(1) bond length is 2.16 Å. All Ru(1)-O(1) bond lengths are 2.04 Å. Co(1) is bonded in an octahedral geometry to six equivalent C(2) atoms. All Co(1)-C(2) bond lengths are 1.85 Å. There are two inequivalent C sites. In the first C site, C(1) is bonded in a trigonal planar geometry to one H(1) and two equivalent O(1) atoms. The C(1)-H(1) bond length is 1.10 Å. Both C(1)-O(1) bond lengths are 1.28 Å. In the second C site, C(2) is bonded in a linear geometry to one Co(1) and one N(1) atom. The C(2)-N(1) bond length is 1.17 Å. N(1) is bonded in a linear geometry to one Ru(1) and one C(2) atom. H(1) is bonded in a single-bond geometry to one C(1) atom. O(1) is bonded in a bent 120 degrees geometry to one Ru(1) and one C(1) atom. Linkers: 6 [C]#N ,12 [O]C=O. Metal clusters: 1 [Co] ,6 [Ru]. The MOF has largest included sphere 3.32 A, density 2.22 g/cm3, surface area 3044.69 m2/g, accessible volume 0.13 cm3/g