Ag7C20H8(NO6)2(CF2)6 crystallizes in the trigonal P3_221 space group. The structure consists of eighteen difluoromethane molecules inside a Ag7C20H8(NO6)2 framework. In the Ag7C20H8(NO6)2 framework, there are four inequivalent Ag sites. In the first Ag site, Ag(1) is bonded in a 3-coordinate geometry to one C(1), one O(3), and one O(5) atom. The Ag(1)-C(1) bond length is 2.15 Å. The Ag(1)-O(3) bond length is 2.35 Å. The Ag(1)-O(5) bond length is 2.29 Å. In the second Ag site, Ag(2) is bonded in a distorted bent 150 degrees geometry to one C(1) and one O(4) atom. The Ag(2)-C(1) bond length is 2.31 Å. The Ag(2)-O(4) bond length is 2.36 Å. In the third Ag site, Ag(3) is bonded in a 3-coordinate geometry to one C(1), one O(2), and one O(4) atom. The Ag(3)-C(1) bond length is 2.20 Å. The Ag(3)-O(2) bond length is 2.57 Å. The Ag(3)-O(4) bond length is 2.51 Å. In the fourth Ag site, Ag(4) is bonded in a distorted water-like geometry to two equivalent C(1), two equivalent C(2), and two equivalent O(6) atoms. Both Ag(4)-C(1) bond lengths are 2.62 Å. Both Ag(4)-C(2) bond lengths are 2.59 Å. Both Ag(4)-O(6) bond lengths are 2.37 Å. There are ten inequivalent C sites. In the first C site, C(1) is bonded in a 5-coordinate geometry to one Ag(1), one Ag(2), one Ag(3), one Ag(4), and one C(2) atom. The C(1)-C(2) bond length is 1.20 Å. In the second C site, C(2) is bonded in a 3-coordinate geometry to one Ag(4), one C(1), and one C(3) atom. The C(2)-C(3) bond length is 1.42 Å. In the third C site, C(3) is bonded in a trigonal planar geometry to one C(2), one C(4), and one C(8) atom. The C(3)-C(4) bond length is 1.39 Å. The C(3)-C(8) bond length is 1.39 Å. In the fourth C site, C(4) is bonded in a distorted single-bond geometry to one C(3) and one H(1,4) atom. The C(4)-H(1,4) bond length is 0.93 Å. In the fifth C site, C(5) is bonded in a distorted single-bond geometry to one C(6) and one H(2) atom. The C(5)-C(6) bond length is 1.39 Å. The C(5)-H(2) bond length is 0.93 Å. In the sixth C site, C(6) is bonded in a trigonal planar geometry to one C(5), one C(7), and one N(1) atom. The C(6)-C(7) bond length is 1.39 Å. The C(6)-N(1) bond length is 1.46 Å. In the seventh C site, C(7) is bonded in a distorted single-bond geometry to one C(6) and one H(3) atom. The C(7)-H(3) bond length is 0.93 Å. In the eighth C site, C(8) is bonded in a distorted single-bond geometry to one C(3) and one H(1,4) atom. The C(8)-H(1,4) bond length is 0.93 Å. In the ninth C site, C(9) is bonded in a distorted bent 120 degrees geometry to one O(3) and one O(4) atom. The C(9)-O(3) bond length is 1.22 Å. The C(9)-O(4) bond length is 1.24 Å. In the tenth C site, C(13) is bonded in a distorted bent 120 degrees geometry to one O(5) and one O(6) atom. The C(13)-O(5) bond length is 1.23 Å. The C(13)-O(6) bond length is 1.24 Å. N(1) is bonded in a trigonal planar geometry to one C(6), one O(1), and one O(2) atom. The N(1)-O(1) bond length is 1.16 Å. The N(1)-O(2) bond length is 1.22 Å. There are three inequivalent H sites. In the first H site, H(1,4) is bonded in a single-bond geometry to one C(4) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(5) atom. In the third H site, H(3) is bonded in a single-bond geometry to one C(7) atom. There are six inequivalent O sites. In the first O site, O(1) is bonded in a single-bond geometry to one N(1) atom. In the second O site, O(2) is bonded in a distorted bent 120 degrees geometry to one Ag(3) and one N(1) atom. In the third O site, O(3) is bonded in a distorted bent 120 degrees geometry to one Ag(1) and one C(9) atom. In the fourth O site, O(4) is bonded in a distorted single-bond geometry to one Ag(2), one Ag(3), and one C(9) atom. In the fifth O site, O(5) is bonded in a distorted single-bond geometry to one Ag(1) and one C(13) atom. In the sixth O site, O(6) is bonded in a distorted bent 120 degrees geometry to one Ag(4) and one C(13) atom. Linkers: 6 [O]C(=O)C(F)(F)C(F)(F)C(F)(F)C([O])=O. Metal clusters: 21 [Ag]. The MOF has largest included sphere 5.05 A, density 2.23 g/cm3, surface area 2697.86 m2/g, accessible volume 0.17 cm3/g