Co5H16(C8O5)4(CH2)6(CH2CO)2 crystallizes in the orthorhombic Fdd2 space group. The structure consists of forty-eight 02329_fluka molecules and sixteen dimethyl ether molecules inside a Co5H16(C8O5)4 framework. In the Co5H16(C8O5)4 framework, there are three inequivalent Co sites. In the first Co site, Co(1) is bonded in a 5-coordinate geometry to one O(1), one O(11), one O(2), one O(4), and one O(8) atom. The Co(1)-O(1) bond length is 2.42 Å. The Co(1)-O(11) bond length is 2.05 Å. The Co(1)-O(2) bond length is 2.08 Å. The Co(1)-O(4) bond length is 2.05 Å. The Co(1)-O(8) bond length is 1.98 Å. In the second Co site, Co(2) is bonded in a rectangular see-saw-like geometry to one O(11), one O(3), one O(7), and one O(9) atom. The Co(2)-O(11) bond length is 2.10 Å. The Co(2)-O(3) bond length is 2.01 Å. The Co(2)-O(7) bond length is 2.06 Å. The Co(2)-O(9) bond length is 1.97 Å. In the third Co site, Co(3) is bonded in a rectangular see-saw-like geometry to two equivalent O(10) and two equivalent O(11) atoms. Both Co(3)-O(10) bond lengths are 2.07 Å. Both Co(3)-O(11) bond lengths are 2.02 Å. There are sixteen inequivalent C sites. In the first C site, C(1) is bonded in a bent 120 degrees geometry to one C(2), one O(1), and one O(2) atom. The C(1)-C(2) bond length is 1.55 Å. The C(1)-O(1) bond length is 1.18 Å. The C(1)-O(2) bond length is 1.28 Å. In the second C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one C(7) atom. The C(2)-C(3) bond length is 1.25 Å. The C(2)-C(7) bond length is 1.36 Å. In the third C site, C(3) is bonded in a distorted single-bond geometry to one C(2), one C(4), and one H(1) atom. The C(3)-C(4) bond length is 1.40 Å. The C(3)-H(1) bond length is 0.93 Å. In the fourth C site, C(4) is bonded in a distorted trigonal planar geometry to one C(3), one C(5), and one O(5) atom. The C(4)-C(5) bond length is 1.28 Å. The C(4)-O(5) bond length is 1.43 Å. In the fifth C site, C(5) is bonded in a distorted single-bond geometry to one C(4), one C(6), and one H(2) atom. The C(5)-C(6) bond length is 1.37 Å. The C(5)-H(2) bond length is 0.93 Å. In the sixth C site, C(6) is bonded in a trigonal planar geometry to one C(5), one C(7), and one C(8) atom. The C(6)-C(7) bond length is 1.41 Å. The C(6)-C(8) bond length is 1.55 Å. In the seventh C site, C(7) is bonded in a distorted single-bond geometry to one C(2), one C(6), and one H(3) atom. The C(7)-H(3) bond length is 0.93 Å. In the eighth C site, C(8) is bonded in a distorted bent 120 degrees geometry to one C(6), one O(3), and one O(4) atom. The C(8)-O(3) bond length is 1.22 Å. The C(8)-O(4) bond length is 1.26 Å. In the ninth C site, C(9) is bonded in a distorted trigonal non-coplanar geometry to two equivalent H(4,5) and one O(5) atom. Both C(9)-H(4,5) bond lengths are 0.97 Å. The C(9)-O(5) bond length is 1.40 Å. In the tenth C site, C(15) is bonded in a distorted single-bond geometry to one C(16) and one H(14) atom. The C(15)-C(16) bond length is 1.36 Å. The C(15)-H(14) bond length is 0.93 Å. In the eleventh C site, C(16) is bonded in a trigonal planar geometry to one C(15), one C(17), and one C(21) atom. The C(16)-C(17) bond length is 1.38 Å. The C(16)-C(21) bond length is 1.55 Å. In the twelfth C site, C(17) is bonded in a distorted single-bond geometry to one C(16), one C(18), and one H(15) atom. The C(17)-C(18) bond length is 1.40 Å. The C(17)-H(15) bond length is 0.93 Å. In the thirteenth C site, C(18) is bonded in a trigonal planar geometry to one C(17), one C(19), and one C(20) atom. The C(18)-C(19) bond length is 1.44 Å. The C(18)-C(20) bond length is 1.38 Å. In the fourteenth C site, C(19) is bonded in a distorted single-bond geometry to one C(18) and one H(16) atom. The C(19)-H(16) bond length is 0.93 Å. In the fifteenth C site, C(20) is bonded in a distorted bent 120 degrees geometry to one C(18), one O(7), and one O(8) atom. The C(20)-O(7) bond length is 1.28 Å. The C(20)-O(8) bond length is 1.29 Å. In the sixteenth C site, C(21) is bonded in a distorted bent 120 degrees geometry to one C(16), one O(10), and one O(9) atom. The C(21)-O(10) bond length is 1.23 Å. The C(21)-O(9) bond length is 1.25 Å. There are seven inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(3) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(5) atom. In the third H site, H(3) is bonded in a single-bond geometry to one C(7) atom. In the fourth H site, H(4,5) is bonded in a single-bond geometry to one C(9) atom. In the fifth H site, H(14) is bonded in a single-bond geometry to one C(15) atom. In the sixth H site, H(15) is bonded in a single-bond geometry to one C(17) atom. In the seventh H site, H(16) is bonded in a single-bond geometry to one C(19) atom. There are ten inequivalent O sites. In the first O site, O(9) is bonded in a distorted bent 120 degrees geometry to one Co(2) and one C(21) atom. In the second O site, O(10) is bonded in a bent 120 degrees geometry to one Co(3) and one C(21) atom. In the third O site, O(11) is bonded in a trigonal non-coplanar geometry to one Co(1), one Co(2), and one Co(3) atom. In the fourth O site, O(1) is bonded in a distorted single-bond geometry to one Co(1) and one C(1) atom. In the fifth O site, O(2) is bonded in an L-shaped geometry to one Co(1) and one C(1) atom. In the sixth O site, O(3) is bonded in a distorted bent 150 degrees geometry to one Co(2) and one C(8) atom. In the seventh O site, O(4) is bonded in a bent 120 degrees geometry to one Co(1) and one C(8) atom. In the eighth O site, O(5) is bonded in a bent 120 degrees geometry to one C(4) and one C(9) atom. In the ninth O site, O(7) is bonded in a distorted bent 120 degrees geometry to one Co(2) and one C(20) atom. In the tenth O site, O(8) is bonded in a bent 120 degrees geometry to one Co(1) and one C(20) atom. Linkers: 16 [O]C(=O)c1cc(OCCCCCOc2cc(C([O])=O)cc(C([O])=O)c2)cc(C([O])=O)c1. Metal clusters: 8 O=[C]O[Co@]12O[C]O[Co](O[C]O[Co]3(O[C]O[Co]4O[C]O[Co@](O[C]=O)(O[C]O4)O3)O1)O[C]O2. The MOF has largest included sphere 4.88 A, density 1.32 g/cm3, surface area 3917.57 m2/g, accessible volume 0.34 cm3/g