Zn2C21NH10O8CF crystallizes in the hexagonal P6_3/mmc space group. The structure consists of six fluoromethane molecules inside a Zn2C21NH10O8 framework. In the Zn2C21NH10O8 framework, Zn(1) is bonded in a distorted square co-planar geometry to two equivalent O(1) and two equivalent O(2) atoms. Both Zn(1)-O(1) bond lengths are 2.01 Å. Both Zn(1)-O(2) bond lengths are 2.02 Å. There are eight inequivalent C sites. In the first C site, C(9) is bonded in a distorted trigonal planar geometry to two equivalent C(6) and one N(1) atom. Both C(9)-C(6) bond lengths are 1.36 Å. The C(9)-N(1) bond length is 1.43 Å. In the second C site, C(1) is bonded in a bent 120 degrees geometry to one C(2), one O(1), and one O(2) atom. The C(1)-C(2) bond length is 1.48 Å. The C(1)-O(1) bond length is 1.25 Å. The C(1)-O(2) bond length is 1.26 Å. In the third C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one C(5) atom. The C(2)-C(3) bond length is 1.38 Å. The C(2)-C(5) bond length is 1.40 Å. In the fourth C site, C(3) is bonded in a distorted single-bond geometry to one C(2), one C(7), and one H(1) atom. The C(3)-C(7) bond length is 1.38 Å. The C(3)-H(1) bond length is 0.95 Å. In the fifth C site, C(4) is bonded in a 1-coordinate geometry to one C(6) and one H(2) atom. The C(4)-C(6) bond length is 1.29 Å. The C(4)-H(2) bond length is 0.95 Å. In the sixth C site, C(5) is bonded in a distorted single-bond geometry to two equivalent C(2) and one H(3) atom. The C(5)-H(3) bond length is 0.95 Å. In the seventh C site, C(6) is bonded in a trigonal planar geometry to one C(4), one C(7), and one C(9) atom. The C(6)-C(7) bond length is 1.50 Å. In the eighth C site, C(7) is bonded in a trigonal planar geometry to one C(6) and two equivalent C(3) atoms. N(1) is bonded in a trigonal planar geometry to one C(9) and two equivalent H(4) atoms. Both N(1)-H(4) bond lengths are 0.88 Å. There are four inequivalent H sites. In the first H site, H(2) is bonded in a single-bond geometry to one C(4) atom. In the second H site, H(3) is bonded in a single-bond geometry to one C(5) atom. In the third H site, H(4) is bonded in a single-bond geometry to one N(1) atom. In the fourth H site, H(1) is bonded in a single-bond geometry to one C(3) atom. There are two inequivalent O sites. In the first O site, O(1) is bonded in a distorted bent 120 degrees geometry to one Zn(1) and one C(1) atom. In the second O site, O(2) is bonded in a distorted bent 120 degrees geometry to one Zn(1) and one C(1) atom. Linkers: 6 Nc1c(-c2cc(C([O])=O)cc(C([O])=O)c2)cc(F)cc1-c1cc(C([O])=O)cc(C([O])=O)c1. Metal clusters: 6 [C]1O[Zn]23O[C]O[Zn](O1)(O[C]O2)O[C]O3. RCSR code: ssa. The MOF has largest included sphere 10.43 A, density 0.78 g/cm3, surface area 3805.09 m2/g, accessible volume 0.81 cm3/g