In4C20H6O23(CH)4C2O crystallizes in the monoclinic P2_1/m space group. The structure consists of two dimethyl ether molecules and four ethane molecules inside a In4C20H6O23 framework. In the In4C20H6O23 framework, there are three inequivalent In sites. In the first In site, In(1) is bonded to one O(1), one O(2), one O(3), one O(8), and one O(9) atom to form corner-sharing InO5 square pyramids. The corner-sharing octahedral tilt angles range from 56-59°. The In(1)-O(1) bond length is 2.11 Å. The In(1)-O(2) bond length is 2.10 Å. The In(1)-O(3) bond length is 2.15 Å. The In(1)-O(8) bond length is 2.16 Å. The In(1)-O(9) bond length is 2.18 Å. In the second In site, In(2) is bonded to two equivalent O(2), two equivalent O(5), and two equivalent O(7) atoms to form corner-sharing InO6 octahedra. Both In(2)-O(2) bond lengths are 2.11 Å. Both In(2)-O(5) bond lengths are 2.17 Å. Both In(2)-O(7) bond lengths are 2.17 Å. In the third In site, In(3) is bonded to two equivalent O(1), two equivalent O(10), and two equivalent O(4) atoms to form corner-sharing InO6 octahedra. Both In(3)-O(1) bond lengths are 2.08 Å. Both In(3)-O(10) bond lengths are 2.17 Å. Both In(3)-O(4) bond lengths are 2.18 Å. There are ten inequivalent C sites. In the first C site, C(1) is bonded in a distorted bent 120 degrees geometry to one C(2), one O(3), and one O(4) atom. The C(1)-C(2) bond length is 1.46 Å. The C(1)-O(3) bond length is 1.25 Å. The C(1)-O(4) bond length is 1.27 Å. In the second C site, C(2) is bonded in a distorted single-bond geometry to one C(1), one C(3), and one O(11) atom. The C(2)-C(3) bond length is 1.34 Å. The C(2)-O(11) bond length is 1.37 Å. In the third C site, C(3) is bonded in a distorted single-bond geometry to one C(2) and one H(1) atom. The C(3)-H(1) bond length is 0.93 Å. In the fourth C site, C(4) is bonded in a distorted single-bond geometry to one C(5) and one H(2) atom. The C(4)-C(5) bond length is 1.33 Å. The C(4)-H(2) bond length is 0.93 Å. In the fifth C site, C(5) is bonded in a distorted trigonal planar geometry to one C(4), one C(6), and one O(11) atom. The C(5)-C(6) bond length is 1.50 Å. The C(5)-O(11) bond length is 1.36 Å. In the sixth C site, C(6) is bonded in a distorted bent 120 degrees geometry to one C(5), one O(5), and one O(6) atom. The C(6)-O(5) bond length is 1.28 Å. The C(6)-O(6) bond length is 1.23 Å. In the seventh C site, C(7) is bonded in a distorted bent 120 degrees geometry to one O(7) and one O(8) atom. The C(7)-O(7) bond length is 1.26 Å. The C(7)-O(8) bond length is 1.25 Å. In the eighth C site, C(10) is bonded in a distorted bent 120 degrees geometry to one C(11), one O(10), and one O(9) atom. The C(10)-C(11) bond length is 1.48 Å. The C(10)-O(10) bond length is 1.26 Å. The C(10)-O(9) bond length is 1.26 Å. In the ninth C site, C(11) is bonded in a distorted single-bond geometry to one C(10), one C(12), and one O(13) atom. The C(11)-C(12) bond length is 1.34 Å. The C(11)-O(13) bond length is 1.37 Å. In the tenth C site, C(12) is bonded in a distorted single-bond geometry to one C(11) and one H(4) atom. The C(12)-H(4) bond length is 0.93 Å. There are three inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(3) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(4) atom. In the third H site, H(4) is bonded in a single-bond geometry to one C(12) atom. There are twelve inequivalent O sites. In the first O site, O(1) is bonded in a bent 120 degrees geometry to one In(1) and one In(3) atom. In the second O site, O(2) is bonded in a bent 120 degrees geometry to one In(1) and one In(2) atom. In the third O site, O(3) is bonded in a bent 150 degrees geometry to one In(1) and one C(1) atom. In the fourth O site, O(4) is bonded in a distorted bent 120 degrees geometry to one In(3) and one C(1) atom. In the fifth O site, O(5) is bonded in a bent 120 degrees geometry to one In(2) and one C(6) atom. In the sixth O site, O(6) is bonded in a single-bond geometry to one C(6) atom. In the seventh O site, O(7) is bonded in a distorted bent 120 degrees geometry to one In(2) and one C(7) atom. In the eighth O site, O(8) is bonded in a distorted single-bond geometry to one In(1) and one C(7) atom. In the ninth O site, O(9) is bonded in a 2-coordinate geometry to one In(1) and one C(10) atom. In the tenth O site, O(10) is bonded in a distorted bent 150 degrees geometry to one In(3) and one C(10) atom. In the eleventh O site, O(11) is bonded in a water-like geometry to one C(2) and one C(5) atom. In the twelfth O site, O(13) is bonded in a water-like geometry to two equivalent C(11) atoms. Linkers: 2 [C]1O[C][C@H]2[CH][CH][C@@H]12.[O][C]=O.[O][C]=O ,6 [O]C(=O)c1ccc(C([O])=O)o1. Metal clusters: 8 [In]. The MOF has largest included sphere 6.38 A, density 1.61 g/cm3, surface area 2865.33 m2/g, accessible volume 0.28 cm3/g