Cu4C44N12H40O11 crystallizes in the tetragonal P-42_1c space group. Cu(1) is bonded to one N(1), one N(2), one O(1), one O(3), and one O(4) atom to form a mixture of edge and corner-sharing CuN2O3 square pyramids. The Cu(1)-N(1) bond length is 2.37 Å. The Cu(1)-N(2) bond length is 2.01 Å. The Cu(1)-O(1) bond length is 1.96 Å. The Cu(1)-O(3) bond length is 1.93 Å. The Cu(1)-O(4) bond length is 1.97 Å. There are eleven inequivalent C sites. In the first C site, C(1) is bonded in a bent 120 degrees geometry to one C(2), one O(1), and one O(2) atom. The C(1)-C(2) bond length is 1.48 Å. The C(1)-O(1) bond length is 1.24 Å. The C(1)-O(2) bond length is 1.24 Å. In the second C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one C(7) atom. The C(2)-C(3) bond length is 1.38 Å. The C(2)-C(7) bond length is 1.39 Å. In the third C site, C(3) is bonded in a distorted trigonal planar geometry to one C(2), one C(4), and one H(1) atom. The C(3)-C(4) bond length is 1.38 Å. The C(3)-H(1) bond length is 0.94 Å. In the fourth C site, C(4) is bonded in a distorted single-bond geometry to one C(3), one C(5), and one H(2) atom. The C(4)-C(5) bond length is 1.38 Å. The C(4)-H(2) bond length is 0.94 Å. In the fifth C site, C(5) is bonded in a distorted trigonal planar geometry to one C(4), one C(6), and one N(3) atom. The C(5)-C(6) bond length is 1.34 Å. The C(5)-N(3) bond length is 1.43 Å. In the sixth C site, C(6) is bonded in a distorted single-bond geometry to one C(5) and one H(3) atom. The C(6)-H(3) bond length is 0.94 Å. In the seventh C site, C(7) is bonded in a distorted single-bond geometry to one C(2) and one H(4) atom. The C(7)-H(4) bond length is 0.94 Å. In the eighth C site, C(8) is bonded in a trigonal non-coplanar geometry to one C(9); one H(5); and two equivalent H(6,7) atoms. The C(8)-C(9) bond length is 1.50 Å. The C(8)-H(5) bond length is 0.97 Å. Both C(8)-H(6,7) bond lengths are 0.97 Å. In the ninth C site, C(9) is bonded in a distorted trigonal planar geometry to one C(8), one N(1), and one N(3) atom. The C(9)-N(1) bond length is 1.28 Å. The C(9)-N(3) bond length is 1.35 Å. In the tenth C site, C(10) is bonded in a distorted trigonal planar geometry to one C(11), one N(2), and one N(3) atom. The C(10)-C(11) bond length is 1.47 Å. The C(10)-N(2) bond length is 1.30 Å. The C(10)-N(3) bond length is 1.37 Å. In the eleventh C site, C(11) is bonded in a trigonal non-coplanar geometry to one C(10); one H(10); and two equivalent H(8,9) atoms. The C(11)-H(10) bond length is 0.97 Å. Both C(11)-H(8,9) bond lengths are 0.97 Å. There are three inequivalent N sites. In the first N site, N(1) is bonded in a 3-coordinate geometry to one Cu(1), one C(9), and one N(2) atom. The N(1)-N(2) bond length is 1.39 Å. In the second N site, N(2) is bonded in a 3-coordinate geometry to one Cu(1), one C(10), and one N(1) atom. In the third N site, N(3) is bonded in a trigonal planar geometry to one C(10), one C(5), and one C(9) atom. There are eight inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(3) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(4) atom. In the third H site, H(3) is bonded in a single-bond geometry to one C(6) atom. In the fourth H site, H(4) is bonded in a single-bond geometry to one C(7) atom. In the fifth H site, H(5) is bonded in a single-bond geometry to one C(8) atom. In the sixth H site, H(6,7) is bonded in a single-bond geometry to one C(8) atom. In the seventh H site, H(8,9) is bonded in a single-bond geometry to one C(11) atom. In the eighth H site, H(10) is bonded in a single-bond geometry to one C(11) atom. There are four inequivalent O sites. In the first O site, O(3) is bonded in a tetrahedral geometry to four equivalent Cu(1) atoms. In the second O site, O(1) is bonded in a bent 120 degrees geometry to one Cu(1) and one C(1) atom. In the third O site, O(2) is bonded in a single-bond geometry to one C(1) atom. In the fourth O site, O(4) is bonded in an L-shaped geometry to two equivalent Cu(1) atoms. Linkers: 8 Cc1nnc(C)n1-c1ccc(C([O])=O)cc1. Metal clusters: 2 O=[C]O[Cu]123[N][N][Cu@]4(O[C]=O)[N][N][Cu](O[C]=O)([N][N][Cu@](O[C]=O)([N][N]1)O4)(O2)O3. The MOF has largest included sphere 7.46 A, density 0.85 g/cm3, surface area 4459.96 m2/g, accessible volume 0.61 cm3/g