Pr2In3H36(C3O)22(C5H3)3 crystallizes in the cubic P2_13 space group. The structure consists of four 1,3,5-triisopropenyl benzene molecules inside a Pr2In3H36(C3O)22 framework. In the Pr2In3H36(C3O)22 framework, there are two inequivalent Pr sites. In the first Pr site, Pr(1) is bonded in a distorted hexagonal planar geometry to three equivalent O(1) and three equivalent O(4) atoms. All Pr(1)-O(1) bond lengths are 2.56 Å. All Pr(1)-O(4) bond lengths are 2.44 Å. In the second Pr site, Pr(2) is bonded to one O(8), three equivalent O(3), and three equivalent O(6) atoms to form PrO7 hexagonal pyramids that share corners with three equivalent In(1)O6 octahedra. The corner-sharing octahedral tilt angles are 61°. The Pr(2)-O(8) bond length is 2.42 Å. All Pr(2)-O(3) bond lengths are 2.54 Å. All Pr(2)-O(6) bond lengths are 2.48 Å. In(1) is bonded to one O(2), one O(5), one O(7), one O(8), and two equivalent O(1) atoms to form InO6 octahedra that share  a cornercorner with one Pr(2)O7 hexagonal pyramid and edges with two equivalent In(1)O6 octahedra. The In(1)-O(2) bond length is 2.13 Å. The In(1)-O(5) bond length is 2.12 Å. The In(1)-O(7) bond length is 2.13 Å. The In(1)-O(8) bond length is 2.16 Å. There is one shorter (2.16 Å) and one longer (2.18 Å) In(1)-O(1) bond length. There are twenty-two inequivalent C sites. In the first C site, C(1) is bonded in a bent 120 degrees geometry to one C(2), one O(2), and one O(3) atom. The C(1)-C(2) bond length is 1.48 Å. The C(1)-O(2) bond length is 1.19 Å. The C(1)-O(3) bond length is 1.25 Å. In the second C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one C(7) atom. The C(2)-C(3) bond length is 1.41 Å. The C(2)-C(7) bond length is 1.38 Å. In the third C site, C(3) is bonded in a distorted single-bond geometry to one C(2), one C(4), and one H(1) atom. The C(3)-C(4) bond length is 1.57 Å. The C(3)-H(1) bond length is 0.93 Å. In the fourth C site, C(4) is bonded in a distorted trigonal planar geometry to one C(3), one C(5), and one H(2) atom. The C(4)-C(5) bond length is 1.45 Å. The C(4)-H(2) bond length is 0.93 Å. In the fifth C site, C(5) is bonded in a trigonal planar geometry to one C(4), one C(6), and one C(8) atom. The C(5)-C(6) bond length is 1.32 Å. The C(5)-C(8) bond length is 1.50 Å. In the sixth C site, C(6) is bonded in a distorted single-bond geometry to one C(5) and one H(3) atom. The C(6)-H(3) bond length is 0.93 Å. In the seventh C site, C(7) is bonded in a distorted single-bond geometry to one C(2) and one H(4) atom. The C(7)-H(4) bond length is 0.93 Å. In the eighth C site, C(8) is bonded in a trigonal planar geometry to one C(5) and two equivalent C(9) atoms. There is one shorter (1.31 Å) and one longer (1.47 Å) C(8)-C(9) bond length. In the ninth C site, C(9) is bonded in a single-bond geometry to two equivalent C(8) and one H(5) atom. The C(9)-H(5) bond length is 0.93 Å. In the tenth C site, C(10) is bonded in a bent 120 degrees geometry to one C(11), one O(4), and one O(5) atom. The C(10)-C(11) bond length is 1.50 Å. The C(10)-O(4) bond length is 1.23 Å. The C(10)-O(5) bond length is 1.36 Å. In the eleventh C site, C(11) is bonded in a trigonal planar geometry to one C(10), one C(12), and one C(16) atom. The C(11)-C(12) bond length is 1.34 Å. The C(11)-C(16) bond length is 1.34 Å. In the twelfth C site, C(12) is bonded in a distorted single-bond geometry to one C(11) and one H(6) atom. The C(12)-H(6) bond length is 0.93 Å. In the thirteenth C site, C(13) is bonded in a distorted single-bond geometry to one C(14) and one H(7) atom. The C(13)-C(14) bond length is 1.43 Å. The C(13)-H(7) bond length is 0.93 Å. In the fourteenth C site, C(14) is bonded in a trigonal planar geometry to one C(13), one C(15), and one C(17) atom. The C(14)-C(15) bond length is 1.32 Å. The C(14)-C(17) bond length is 1.57 Å. In the fifteenth C site, C(15) is bonded in a distorted trigonal planar geometry to one C(14), one C(16), and one H(8) atom. The C(15)-C(16) bond length is 1.29 Å. The C(15)-H(8) bond length is 0.93 Å. In the sixteenth C site, C(16) is bonded in a distorted trigonal planar geometry to one C(11), one C(15), and one H(9) atom. The C(16)-H(9) bond length is 0.93 Å. In the seventeenth C site, C(17) is bonded in a trigonal planar geometry to one C(14) and two equivalent C(18) atoms. There is one shorter (1.33 Å) and one longer (1.37 Å) C(17)-C(18) bond length. In the eighteenth C site, C(18) is bonded in a single-bond geometry to two equivalent C(17) and one H(10) atom. The C(18)-H(10) bond length is 0.93 Å. In the nineteenth C site, C(19) is bonded in a single-bond geometry to one C(23) and one H(11) atom. The C(19)-C(23) bond length is 1.43 Å. The C(19)-H(11) bond length is 0.93 Å. In the twentieth C site, C(20) is bonded in a distorted bent 120 degrees geometry to one C(23), one O(6), and one O(7) atom. The C(20)-C(23) bond length is 1.43 Å. The C(20)-O(6) bond length is 1.44 Å. The C(20)-O(7) bond length is 1.30 Å. In the twenty-first C site, C(23) is bonded in a trigonal planar geometry to one C(19), one C(20), and one C(24) atom. The C(23)-C(24) bond length is 1.43 Å. In the twenty-second C site, C(24) is bonded in a distorted single-bond geometry to one C(23) and one H(13) atom. The C(24)-H(13) bond length is 0.93 Å. There are twelve inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(3) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(4) atom. In the third H site, H(3) is bonded in a single-bond geometry to one C(6) atom. In the fourth H site, H(4) is bonded in a single-bond geometry to one C(7) atom. In the fifth H site, H(5) is bonded in a single-bond geometry to one C(9) atom. In the sixth H site, H(6) is bonded in a single-bond geometry to one C(12) atom. In the seventh H site, H(7) is bonded in a single-bond geometry to one C(13) atom. In the eighth H site, H(8) is bonded in a single-bond geometry to one C(15) atom. In the ninth H site, H(9) is bonded in a single-bond geometry to one C(16) atom. In the tenth H site, H(10) is bonded in a single-bond geometry to one C(18) atom. In the eleventh H site, H(11) is bonded in a single-bond geometry to one C(19) atom. In the twelfth H site, H(13) is bonded in a single-bond geometry to one C(24) atom. There are eight inequivalent O sites. In the first O site, O(1) is bonded in a trigonal non-coplanar geometry to one Pr(1) and two equivalent In(1) atoms. In the second O site, O(2) is bonded in a bent 120 degrees geometry to one In(1) and one C(1) atom. In the third O site, O(3) is bonded in a distorted single-bond geometry to one Pr(2) and one C(1) atom. In the fourth O site, O(4) is bonded in a bent 150 degrees geometry to one Pr(1) and one C(10) atom. In the fifth O site, O(5) is bonded in a bent 120 degrees geometry to one In(1) and one C(10) atom. In the sixth O site, O(6) is bonded in a distorted single-bond geometry to one Pr(2) and one C(20) atom. In the seventh O site, O(7) is bonded in a bent 120 degrees geometry to one In(1) and one C(20) atom. In the eighth O site, O(8) is bonded in a tetrahedral geometry to one Pr(2) and three equivalent In(1) atoms. Linkers: 12 [O]C(=O)c1ccc(-c2cc(-c3ccc(C([O])=O)cc3)cc(-c3ccc(C([O])=O)cc3)c2)cc1. Metal clusters: 4 [O][Pr]12([O])([O])O[C]O[In]3O[C]O[Pr]4([O])(O[C]O3)(O[C]O[In](O[C]O1)O[C]O4)O[C]O[In](O[C]=O)O[C]O2. The MOF has largest included sphere 10.27 A, density 0.66 g/cm3, surface area 3338.21 m2/g, accessible volume 1.21 cm3/g