In12C54H18O49 crystallizes in the hexagonal P6_3/mmc space group. There are three inequivalent In sites. In the first In site, In(1) is bonded to one O(4), two equivalent O(2), and two equivalent O(6) atoms to form InO5 square pyramids that share  a cornercorner with one In(2)O6 octahedra and corners with two equivalent In(1)O5 square pyramids. The corner-sharing octahedral tilt angles are 59°. The In(1)-O(4) bond length is 2.12 Å. Both In(1)-O(2) bond lengths are 2.19 Å. Both In(1)-O(6) bond lengths are 2.11 Å. In the second In site, In(2) is bonded to two equivalent O(4) and four equivalent O(3) atoms to form corner-sharing InO6 octahedra. Both In(2)-O(4) bond lengths are 2.09 Å. All In(2)-O(3) bond lengths are 2.16 Å. In the third In site, In(3) is bonded to one O(5) and four equivalent O(1) atoms to form corner-sharing InO5 square pyramids. The In(3)-O(5) bond length is 2.05 Å. All In(3)-O(1) bond lengths are 2.18 Å. There are six inequivalent C sites. In the first C site, C(4) is bonded in a distorted bent 120 degrees geometry to one C(5) and two equivalent O(1) atoms. The C(4)-C(5) bond length is 1.53 Å. Both C(4)-O(1) bond lengths are 1.25 Å. In the second C site, C(5) is bonded in a trigonal planar geometry to one C(4) and two equivalent C(3) atoms. Both C(5)-C(3) bond lengths are 1.39 Å. In the third C site, C(6) is bonded in a single-bond geometry to two equivalent C(2) and one H(2) atom. Both C(6)-C(2) bond lengths are 1.42 Å. The C(6)-H(2) bond length is 0.93 Å. In the fourth C site, C(1) is bonded in a distorted bent 120 degrees geometry to one C(2), one O(2), and one O(3) atom. The C(1)-C(2) bond length is 1.50 Å. The C(1)-O(2) bond length is 1.26 Å. The C(1)-O(3) bond length is 1.26 Å. In the fifth C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one C(6) atom. The C(2)-C(3) bond length is 1.39 Å. In the sixth C site, C(3) is bonded in a distorted single-bond geometry to one C(2), one C(5), and one H(1) atom. The C(3)-H(1) bond length is 0.93 Å. There are two inequivalent H sites. In the first H site, H(2) is bonded in a single-bond geometry to one C(6) atom. In the second H site, H(1) is bonded in a single-bond geometry to one C(3) atom. There are six inequivalent O sites. In the first O site, O(1) is bonded in a distorted bent 120 degrees geometry to one In(3) and one C(4) atom. In the second O site, O(2) is bonded in a distorted bent 150 degrees geometry to one In(1) and one C(1) atom. In the third O site, O(3) is bonded in a distorted bent 150 degrees geometry to one In(2) and one C(1) atom. In the fourth O site, O(4) is bonded in a bent 120 degrees geometry to one In(1) and one In(2) atom. In the fifth O site, O(5) is bonded in a trigonal planar geometry to three equivalent In(3) atoms. In the sixth O site, O(6) is bonded in a bent 150 degrees geometry to two equivalent In(1) atoms. Linkers: 12 [O]C(=O)c1cc(C([O])=O)cc(C([O])=O)c1. Metal clusters: 18 [In] ,2 O=[C]O[In]O[C]O[In]1O[C]O[In](O[C]=O)O1.[O][C]=O.[O][C]=O. The MOF has largest included sphere 8.89 A, density 1.42 g/cm3, surface area 2540.09 m2/g, accessible volume 0.41 cm3/g