Mn6C48N8H36S6O27 crystallizes in the trigonal R-3c space group. Mn(1) is bonded to one N(1), one O(1), one O(2), one O(4), and one O(5) atom to form MnNO4 square pyramids that share  a cornercorner with one Mn(1)NO4 square pyramid,  a cornercorner with one C(8)H2N2 tetrahedra, and corners with two equivalent C(7)H2N2 tetrahedra. The Mn(1)-N(1) bond length is 2.34 Å. The Mn(1)-O(1) bond length is 2.15 Å. The Mn(1)-O(2) bond length is 2.14 Å. The Mn(1)-O(4) bond length is 2.17 Å. The Mn(1)-O(5) bond length is 2.24 Å. There are eight inequivalent C sites. In the first C site, C(5) is bonded in a trigonal planar geometry to one C(4), one C(6), and one S(1) atom. The C(5)-C(4) bond length is 1.36 Å. The C(5)-C(6) bond length is 1.50 Å. The C(5)-S(1) bond length is 1.71 Å. In the second C site, C(6) is bonded in a distorted bent 120 degrees geometry to one C(5), one O(3), and one O(4) atom. The C(6)-O(3) bond length is 1.24 Å. The C(6)-O(4) bond length is 1.25 Å. In the third C site, C(7) is bonded to two equivalent N(1) and two equivalent H(3,4) atoms to form CH2N2 tetrahedra that share corners with two equivalent Mn(1)NO4 square pyramids, corners with two equivalent C(7)H2N2 tetrahedra, and corners with two equivalent C(8)H2N2 tetrahedra. There is one shorter (1.49 Å) and one longer (1.50 Å) C(7)-N(1) bond length. Both C(7)-H(3,4) bond lengths are 0.97 Å. In the fourth C site, C(8) is bonded to one N(1), one N(2), one H(5), and one H(6) atom to form CH2N2 tetrahedra that share  a cornercorner with one Mn(1)NO4 square pyramid, corners with two equivalent C(7)H2N2 tetrahedra, and corners with two equivalent C(8)H2N2 tetrahedra. The C(8)-N(1) bond length is 1.49 Å. The C(8)-N(2) bond length is 1.45 Å. The C(8)-H(5) bond length is 0.97 Å. The C(8)-H(6) bond length is 0.97 Å. In the fifth C site, C(1) is bonded in a distorted bent 120 degrees geometry to one C(2), one O(1), and one O(2) atom. The C(1)-C(2) bond length is 1.50 Å. The C(1)-O(1) bond length is 1.25 Å. The C(1)-O(2) bond length is 1.25 Å. In the sixth C site, C(2) is bonded in a trigonal planar geometry to one C(1), one C(3), and one S(1) atom. The C(2)-C(3) bond length is 1.36 Å. The C(2)-S(1) bond length is 1.72 Å. In the seventh C site, C(3) is bonded in a distorted single-bond geometry to one C(2) and one H(1) atom. The C(3)-H(1) bond length is 0.93 Å. In the eighth C site, C(4) is bonded in a distorted single-bond geometry to one C(5) and one H(2) atom. The C(4)-H(2) bond length is 0.93 Å. There are two inequivalent N sites. In the first N site, N(1) is bonded to one Mn(1), one C(8), and two equivalent C(7) atoms to form corner-sharing NMnC3 tetrahedra. In the second N site, N(2) is bonded in a trigonal non-coplanar geometry to three equivalent C(8) atoms. There are five inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(3) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(4) atom. In the third H site, H(3,4) is bonded in a single-bond geometry to one C(7) atom. In the fourth H site, H(5) is bonded in a single-bond geometry to one C(8) atom. In the fifth H site, H(6) is bonded in a single-bond geometry to one C(8) atom. S(1) is bonded in an L-shaped geometry to one C(2) and one C(5) atom. There are five inequivalent O sites. In the first O site, O(5) is bonded in a bent 120 degrees geometry to two equivalent Mn(1) atoms. In the second O site, O(1) is bonded in a distorted bent 120 degrees geometry to one Mn(1) and one C(1) atom. In the third O site, O(2) is bonded in a distorted bent 150 degrees geometry to one Mn(1) and one C(1) atom. In the fourth O site, O(3) is bonded in a single-bond geometry to one C(6) atom. In the fifth O site, O(4) is bonded in a bent 120 degrees geometry to one Mn(1) and one C(6) atom. Linkers: 3 C1N2CN3CN1CN(C2)C3 ,12 [O]C(=O)c1ccc(C([O])=O)s1. Metal clusters: 6 [Mn] ,3 O=[C]O[Mn@]12O[C]O[Mn@](O[C]=O)(O[C]O1)O2. The MOF has largest included sphere 5.30 A, density 1.22 g/cm3, surface area 3823.97 m2/g, accessible volume 0.40 cm3/g