Cu5C20H8(N2O3)4 crystallizes in the monoclinic P2_1/c space group. There are three inequivalent Cu sites. In the first Cu site, Cu(1) is bonded in a rectangular see-saw-like geometry to one N(2), one O(1), one O(2), and one O(3) atom. The Cu(1)-N(2) bond length is 1.99 Å. The Cu(1)-O(1) bond length is 1.95 Å. The Cu(1)-O(2) bond length is 1.98 Å. The Cu(1)-O(3) bond length is 1.90 Å. In the second Cu site, Cu(2) is bonded in a rectangular see-saw-like geometry to one N(1), one N(3), one N(4), and one O(4) atom. The Cu(2)-N(1) bond length is 1.99 Å. The Cu(2)-N(3) bond length is 2.03 Å. The Cu(2)-N(4) bond length is 2.00 Å. The Cu(2)-O(4) bond length is 1.96 Å. In the third Cu site, Cu(3) is bonded in a square co-planar geometry to two equivalent O(5) and two equivalent O(6) atoms. Both Cu(3)-O(5) bond lengths are 1.96 Å. Both Cu(3)-O(6) bond lengths are 1.92 Å. There are ten inequivalent C sites. In the first C site, C(1) is bonded in a distorted bent 120 degrees geometry to one C(2), one N(1), and one O(3) atom. The C(1)-C(2) bond length is 1.42 Å. The C(1)-N(1) bond length is 1.37 Å. The C(1)-O(3) bond length is 1.28 Å. In the second C site, C(2) is bonded in a distorted trigonal planar geometry to one C(1), one C(3), and one N(2) atom. The C(2)-C(3) bond length is 1.49 Å. The C(2)-N(2) bond length is 1.33 Å. In the third C site, C(3) is bonded in a distorted bent 120 degrees geometry to one C(2), one O(1), and one O(2) atom. The C(3)-O(1) bond length is 1.26 Å. The C(3)-O(2) bond length is 1.27 Å. In the fourth C site, C(4) is bonded in a distorted trigonal planar geometry to one C(5), one N(2), and one H(1) atom. The C(4)-C(5) bond length is 1.39 Å. The C(4)-N(2) bond length is 1.34 Å. The C(4)-H(1) bond length is 0.95 Å. In the fifth C site, C(5) is bonded in a distorted bent 120 degrees geometry to one C(4), one N(1), and one H(2) atom. The C(5)-N(1) bond length is 1.34 Å. The C(5)-H(2) bond length is 0.95 Å. In the sixth C site, C(6) is bonded in a distorted bent 120 degrees geometry to one C(7), one N(4), and one O(6) atom. The C(6)-C(7) bond length is 1.43 Å. The C(6)-N(4) bond length is 1.36 Å. The C(6)-O(6) bond length is 1.27 Å. In the seventh C site, C(7) is bonded in a distorted trigonal planar geometry to one C(6), one C(8), and one N(3) atom. The C(7)-C(8) bond length is 1.50 Å. The C(7)-N(3) bond length is 1.33 Å. In the eighth C site, C(8) is bonded in a bent 120 degrees geometry to one C(7), one O(4), and one O(5) atom. The C(8)-O(4) bond length is 1.26 Å. The C(8)-O(5) bond length is 1.25 Å. In the ninth C site, C(9) is bonded in a distorted bent 120 degrees geometry to one N(3) and one H(3) atom. The C(9)-N(3) bond length is 1.33 Å. The C(9)-H(3) bond length is 0.95 Å. In the tenth C site, C(10) is bonded in a distorted bent 120 degrees geometry to one N(4) and one H(4) atom. The C(10)-N(4) bond length is 1.34 Å. The C(10)-H(4) bond length is 0.95 Å. There are four inequivalent N sites. In the first N site, N(1) is bonded in a trigonal planar geometry to one Cu(2), one C(1), and one C(5) atom. In the second N site, N(2) is bonded in a trigonal planar geometry to one Cu(1), one C(2), and one C(4) atom. In the third N site, N(3) is bonded in a trigonal planar geometry to one Cu(2), one C(7), and one C(9) atom. In the fourth N site, N(4) is bonded in a trigonal planar geometry to one Cu(2), one C(10), and one C(6) atom. There are four inequivalent H sites. In the first H site, H(1) is bonded in a single-bond geometry to one C(4) atom. In the second H site, H(2) is bonded in a single-bond geometry to one C(5) atom. In the third H site, H(3) is bonded in a single-bond geometry to one C(9) atom. In the fourth H site, H(4) is bonded in a single-bond geometry to one C(10) atom. There are six inequivalent O sites. In the first O site, O(1) is bonded in a bent 120 degrees geometry to one Cu(1) and one C(3) atom. In the second O site, O(2) is bonded in a bent 120 degrees geometry to one Cu(1) and one C(3) atom. In the third O site, O(3) is bonded in a distorted bent 120 degrees geometry to one Cu(1) and one C(1) atom. In the fourth O site, O(4) is bonded in a bent 120 degrees geometry to one Cu(2) and one C(8) atom. In the fifth O site, O(5) is bonded in a bent 120 degrees geometry to one Cu(3) and one C(8) atom. In the sixth O site, O(6) is bonded in a bent 120 degrees geometry to one Cu(3) and one C(6) atom. Linkers: 3 [O]C(=O)C1=N[CH]C=NC1=O ,4 [O]C(=O)C1=NC=C[N]C1=O. Metal clusters: 10 [Cu]. The MOF has largest included sphere 5.04 A, density 1.35 g/cm3, surface area 3115.18 m2/g, accessible volume 0.34 cm3/g