[biological_process] amyloid precursor protein catabolic process <sep> amyloid-beta metabolic process <sep> calcium ion transport <sep> intracellular signal transduction <sep> membrane protein ectodomain proteolysis <sep> mitochondrion-endoplasmic reticulum membrane tethering <sep> negative regulation of apoptotic process <sep> Notch receptor processing <sep> Notch signaling pathway <sep> protein processing <sep> regulation of calcium import into the mitochondrion