[biological_process] symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity <sep> symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity <sep> symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT2 activity <sep> symbiont-mediated suppression of host type I interferon-mediated signaling pathway <sep> virus-mediated perturbation of host defense response