[biological_process] DNA-templated transcription <sep> regulation of DNA-templated transcription <sep> regulation of proteolysis <sep> symbiont-mediated perturbation of host apoptosis <sep> symbiont-mediated perturbation of host ubiquitin-like protein modification <sep> symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity <sep> symbiont-mediated suppression of host type I interferon-mediated signaling pathway <sep> virus-mediated perturbation of host defense response