anchor.diff:  
   WORKDIR $RNA
   
  -RUN apt-get update
  +RUN apt-get update -m
   RUN apt-get upgrade -y
   
   # Install all required packages
   RUN apt-get install -y \
       bedtools \
       ca-certificates \
  +    cpanminus \
       curl \
       default-mysql-client \
       devscripts \
  
positive.code:     hmmer \
      jq \
      lftp \
      libsqlite3-dev \
      libssl1.1 \
      libxml2-utils \
      libzip-dev \
      moreutils \
  
negative.code: # Install useful pip version
  RUN curl https://bootstrap.pypa.io/get-pip.py -o get-pip.py && python get-pip.py
  
  ENV NCBI="$RNA/ncbi"
  WORKDIR $NCBI
  RUN curl -s ftp://ftp.ncbi.nlm.nih.gov/entrez/entrezdirect/edirect.tar.gz |\
      tar xzf - && \
      cpanm HTML::Entities && \
      edirect/setup.sh
  
  # Install python requirements
  ENV RNACENTRAL_IMPORT_PIPELINE "$RNA/rnacentral-import-pipeline"
  
  