anchor.diff:      && chmod 777 /usr/local/bin/seq2hla/seq2HLA.py 
   
   #Fred2
  -RUN pip install --upgrade pip && pip install git+https://github.com/FRED-2/Fred2@master
  +#RUN pip install --upgrade pip && pip install git+https://github.com/FRED-2/Fred2@master
   
   
   #set envirnomental variables for prediction methods
  
positive.code:     matplotlib \
      tables \
      pandas \
      future
  
  #installing optitype form git repository (version Dec 09 2015) and wirtig config.ini
  RUN git clone https://github.com/FRED-2/OptiType.git \
  
negative.code: ENV HDF5_DIR /usr/local/
  
  RUN pip install --upgrade pip && pip install \
      setuptools==33.1.1 \
      cython \
      numpy \
      pyomo \
  