anchor.diff:  RUN /google-cloud-sdk/install.sh -q
   
   # python packages
  -RUN python3 -m pip install hail
  -RUN python3 -m pip install ipython
   RUN python3 -m pip install --upgrade gsutil
  -
  -RUN install_packages python-pkg-resources
  -
   
   # install GCS connector using the same steps as in https://raw.githubusercontent.com/broadinstitute/install-gcs-connector/master/install_gcs_connector.py
   # assumes ~/.config/gcloud/application_default_credentials.json will be mounted into the docker container
  +RUN python3 -m pip install hail
   COPY spark-defaults.conf /usr/local/lib/python3.7/site-packages/pyspark/conf/spark-defaults.conf
   RUN wget https://repo1.maven.org/maven2/com/google/cloud/bigdataoss/gcs-connector/hadoop2-1.9.17/gcs-connector-hadoop2-1.9.17-shaded.jar -O /usr/local/lib/python3.7/site-packages/pyspark/jars/gcs-connector-hadoop2-1.9.17-shaded.jar
   
  
positive.code: RUN cd /ensembl-vep-release-${VEP_VERSION} && perl INSTALL.pl -a ap -n -l -g all
  RUN ln -s /ensembl-vep-release-${VEP_VERSION}/vep /vep
  
  COPY vep-GRCh37.json /
  COPY vep-GRCh38.json /
  
  
negative.code: 	&& make install \
  	&& make clean
  
  RUN install_packages python-pkg-resources
  
  
  # install gcloud tools
  RUN python3 -m pip install --upgrade pip
  
  