anchor.diff:  RUN pip install --upgrade pip && pip install \
       setuptools==33.1.1 \
       tornado==4.5.3 \
  -    cython \
  -    numpy \
  -    pyomo \
  -    pysam \
  -    matplotlib \
  -    tables \
  -    pandas \
  -    future \
  +    numpy==1.14.5 \
  +    pyomo==4.4.1 \
  +    pysam==0.14.1 \
  +    tables==3.4.4 \
  +    pandas==0.23.2 \
  +    future==0.16.0 \
  +    matplotlib==1.4.3 \
       && pip install git+https://github.com/FRED-2/Fred2@master
   
   #installing optitype form git repository (version Dec 09 2015) and wirtig config.ini
  
positive.code:     bowtie \
      libbz2-dev \
      liblzma-dev \
  && update-alternatives --install /usr/bin/gcc gcc /usr/bin/gcc-4.9 60 --slave /usr/bin/g++ g++ /usr/bin/g++-4.9 \
  && rm -rf /var/lib/apt/lists/* \
  && apt-get clean \
  
negative.code:     git \
      mercurial \
      curl \
      libcurl4-openssl-dev \
      pkg-config \
      python \
      python-pip \
      python-dev \
      cython \
      libfreetype6-dev \
      libmysqlclient-dev \
      libboost-dev \
      libboost-serialization-dev \
  