anchor.diff:      python ./scripts/manage_tool_dependencies.py -c "$GALAXY_CONFIG_FILE" init_if_needed && \
       # Install all required Node dependencies. This is required to get proxy support to work for Interactive Environments
       cd $GALAXY_ROOT/lib/galaxy/web/proxy/js && \
  -    npm install
  +    npm install && \
  +    rm -rf ~/.cache/ /galaxy-central/client/node_modules/
   
   # the following can be removed with 18.01
  -RUN /tool_deps/_conda/bin/conda create -y --override-channels --channel iuc --channel conda-forge --channel bioconda --channel defaults --name mulled-v1-eb2018fd3ce0fcbcee48a4bf89c57219add691c16729281b6c46b30f08339397 samtools=1.3.1 bcftools=1.5
  +RUN /tool_deps/_conda/bin/conda create -y --override-channels --channel iuc --channel conda-forge --channel bioconda --channel defaults --name mulled-v1-eb2018fd3ce0fcbcee48a4bf89c57219add691c16729281b6c46b30f08339397 samtools=1.3.1 bcftools=1.5 && \
  +    /tool_deps/_conda/bin/conda clean --all --yes
   
   # Switch back to User root
   USER root
  
positive.code:     --extra-vars supervisor_postgres_autostart=false \
      --extra-vars nginx_use_remote_header=True \
      --tags=galaxyextras,cvmfs -c local && \
      apt-get autoremove -y && apt-get clean && rm -rf /var/lib/apt/lists/* /tmp/* /var/tmp/*
  
  RUN mkdir /shed_tools && chown $GALAXY_USER:$GALAXY_USER /shed_tools && \
      mkdir $EXPORT_DIR/ftp/ && chown $GALAXY_USER:$GALAXY_USER $EXPORT_DIR/ftp && \
  
negative.code:     $GALAXY_VIRTUAL_ENV/bin/pip2 install pip --upgrade && \
      $GALAXY_VIRTUAL_ENV/bin/pip2 install --extra-index-url https://wheels.galaxyproject.org/ uwsgi==2.0.15 -v --pre && \
      chown -R $GALAXY_USER:$GALAXY_USER $GALAXY_VIRTUAL_ENV && \
      rm -rf ~/.cache/ /galaxy-central/client/node_modules/
  
  RUN su $GALAXY_USER -c "cp $GALAXY_ROOT/config/galaxy.yml.sample $GALAXY_CONFIG_FILE"
  ADD ./reports_wsgi.ini.sample $GALAXY_CONFIG_DIR/reports_wsgi.ini
  