anchor.diff:  
   
   ##########################################################################################
  -# ALEA 1.t.2
  +# ALEA2 2.0
   ##########################################################################################
   
   ENV ALEA_INSTALL_DIR=/opt/alea
  -ENV ALEA_VERSION=rt
  +ENV ALEA_VERSION=2.0
   ENV ALEA_FILENAME=alea.${ALEA_VERSION}.tar.gz
   #ENV ALEA_URL=https://github.com/hyounesy/ALEA/raw/Task/dist/${ALEA_FILENAME}
   #https://github.com/hyounesy/ALEA/raw/master/dist/alea.1.2.2.tar.gz
   
  -ENV ALEA_URL=https://datahub-7ak6xof0.udes.genap.ca/${ALEA_FILENAME}
  -
  -
  -WORKDIR /tmp
  -#COPY  ${ALEA_FILENAME} ${ALEA_FILENAME}
  -RUN wget -q $ALEA_URL && \
  -  tar -zxvf ${ALEA_FILENAME} -C /opt && \
  +ENV ALEA_URL=https://github.com/hyounesy/ALEA/raw/master/dist/${ALEA_FILENAME}
  +
  +
  +WORKDIR /tmp
  +COPY  ${ALEA_FILENAME} ${ALEA_FILENAME}
  +RUN wget -q $ALEA_URL
  +RUN  tar -zxvf ${ALEA_FILENAME} -C /opt && \
     rm -f /tmp/${ALEA_FILENAME}
   
   
  
positive.code:   ln -s /opt/shapeit/bin/shapeit $ALEA_INSTALL_DIR/bin/ && \
    find $VCFTOOLS_INSTALL_DIR/bin/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/ && \
    find /opt/bedtools2/bin/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/ && \
    find /opt/bedtools2.2/bedtools2/bin/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/bedtools2.2 && \
    find /opt/bedops/bin/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/ && \
    find /opt/bismark_v0.16.3/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/ && \
    find /opt/tophat-2.1.1.Linux_x86_64/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} $ALEA_INSTALL_DIR/bin/ && \
    ln -s /opt/STAR-2.5.3a/source/STAR $ALEA_INSTALL_DIR/bin/
  
  RUN  find /opt/bowtie2-2.2.9/ -maxdepth 1 -perm -+x -type f | xargs -i ln -s {} /usr/local/bin/ 
  
  
negative.code: 
  WORKDIR /tmp
  RUN wget -q https://github.com/arq5x/bedtools2/releases/download/v2.22.0/bedtools-2.22.0.tar.gz && \
    mkdir /opt/bedtools22/ && \
    tar -xf bedtools-2.22.0.tar.gz -C /opt/bedtools22/
  WORKDIR /opt/bedtools22/bedtools2
  RUN make && \
    rm -f /tmp/bedtools-2.22.0.tar.gz
  
  