anchor.diff:  liblzma5 \
   libncurses5 \
   p11-kit \
  +libcurl3-gnutls \
  +libcurl4 \
  +moreutils \
  +google-perftools \
   unattended-upgrades && \
   unattended-upgrade -d -v && \
   apt-get remove -yq unattended-upgrades && \
  
positive.code: COPY . .
  RUN bash build/opt-build-local.sh $OPT
  
  FROM ubuntu:16.04
  
  LABEL maintainer="cgphelp@sanger.ac.uk" \
        uk.ac.sanger.cgp="Cancer, Ageing and Somatic Mutation, Wellcome Trust Sanger Institute" \
  
negative.code: ENV VER_VCFTOOLS="0.1.16"
  
  RUN apt-get -yq update
  RUN apt-get install -yq --no-install-recommends locales
  RUN apt-get install -yq --no-install-recommends g++
  RUN apt-get install -yq --no-install-recommends make
  RUN apt-get install -yq --no-install-recommends gcc
  RUN apt-get install -yq --no-install-recommends pkg-config
  RUN apt-get install -yq --no-install-recommends zlib1g-dev
  
  RUN locale-gen en_US.UTF-8
  RUN update-locale LANG=en_US.UTF-8
  