anchor.diff:  	wget \
   	unzip \
   	tabix \
  -	libncurses5-dev
  +	libncurses5-dev \
  +	bedtools \ 
  +	dos2unix \
  +	python3 \
  +	python3-pip \
  +	r-base \
  +	r-base-dev \
  +	dpkg-dev \
  +	libcurl3 \
  +	libcurl3-dev \ 
  +	libffi-dev 
  +
  +RUN pip3 install --upgrade pip
  +RUN pip install synapseclient httplib2 pycrypto aacrgenie
  +RUN pip install pandas numexpr --upgrade
  +
  +RUN rm /usr/bin/python 
  +RUN ln -s /usr/bin/python3 /usr/bin/python 
   
   RUN apt-get install -y cpanminus
   RUN apt-get install -y libmysqlclient-dev
  
positive.code: 	TAP::Harness \
  	Module::Build --force
  
  #ENV VEP_PATH=$HOME/vep
  #ENV VEP_DATA=$HOME/.vep
  #RUN mkdir $VEP_PATH $VEP_DATA $VEP_PATH/htslib $VEP_PATH/samtools $VEP_PATH/samtools/bin
  
  #ENV PERL5LIB=$VEP_PATH:$PERL5LIB
  #ENV PATH=$VEP_PATH/htslib:$PATH
  #ENV PATH=$HOME/vep/samtools/bin:$VEP_PATH/htslib:$PATH
  
  WORKDIR /root
  RUN wget https://github.com/mskcc/vcf2maf/archive/v1.6.14.zip
  RUN unzip v1.6.14.zip
  
negative.code: FROM ubuntu:16.04
  
  RUN echo "deb http://cran.rstudio.com/bin/linux/ubuntu xenial/" | tee -a /etc/apt/sources.list
  RUN gpg --keyserver keyserver.ubuntu.com --recv-key E084DAB9
  