anchor.diff:  RUN Rscript -e 'BiocManager::install("lima1/PSCBS", ref="add_dnacopy_weighting")'
   
   RUN apt-get update \
  -    && apt-get install -y --no-install-recommends apt-utils \
  -    && apt-get install -y --no-install-recommends \
  -    texlive \
  -    texlive-latex-extra \
  -    texlive-fonts-extra \
  -    texlive-bibtex-extra \
  -    texlive-science \
  -    texi2html \
  -    texinfo \
  -    python-is-python3 \
  +    && apt-get install -y --no-install-recommends apt-utils python-is-python3 \
       && apt-get clean \
       && rm -rf /var/lib/apt/lists/*
  +
  +# RUN apt-get install -y --no-install-recommends \
  +#     texlive \
  +#     texlive-latex-extra \
  +#     texlive-fonts-extra \
  +#     texlive-bibtex-extra \
  +#     texlive-science \
  +#     texi2html \
  +#     texinfo \
  +#     && apt-get clean \
  +#     && rm -rf /var/lib/apt/lists/*
   
   # install GenomicsDB
   ENV GENOMICSDB_PATH=/opt/GenomicsDB
  
positive.code: remotes::install_github("nalinigans/GenomicsDB-R", ref="master", configure.args="--with-genomicsdb=/opt/GenomicsDB/")'
  
  # install PureCN
  RUN Rscript -e 'BiocManager::install("lima1/PureCN", dependencies = TRUE)'
  ENV PURECN=/usr/local/lib/R/site-library/PureCN/extdata
  
  # add symbolic link and paths
  
negative.code: FROM bioconductor/bioconductor_docker:RELEASE_3_15
  #FROM bioconductor/bioconductor_docker:devel
  
  # install base packages
  RUN Rscript -e 'if (!requireNamespace("BiocManager", quietly = TRUE)){install.packages("BiocManager")}; \
  