anchor.diff:  #Prediction Tools (generate a zip with all prediction tool binaries and wget it form our servers)
   #UN wget http://abi.informatik.uni-tuebingen.de/pkg_predictors.tar.gz \
   
  -RUN wget http://www-bs3.informatik.uni-tuebingen.de/extern/schubert/pkg_predictors.tar.gz \
  +RUN wget --secure-protocol=TLSv1 http://www-bs3.informatik.uni-tuebingen.de/extern/schubert/pkg_predictors.tar.gz \
       && tar -xvf pkg_predictors.tar.gz  -C /usr/local/ \
       && rm pkg_predictors.tar.gz
   
  
positive.code: 
  #HLA Typing
  #OptiType dependecies
  RUN wget https://www.hdfgroup.org/ftp/HDF5/current/bin/linux-centos7-x86_64-gcc485/hdf5-1.8.17-linux-centos7-x86_64-gcc485-shared.tar.gz \
      && tar -xvf hdf5-1.8.17-linux-centos7-x86_64-gcc485-shared.tar.gz \
      && mv hdf5-1.8.17-linux-centos7-x86_64-gcc485-shared/bin/* /usr/local/bin/ \
      && mv hdf5-1.8.17-linux-centos7-x86_64-gcc485-shared/lib/* /usr/local/lib/ \
  
negative.code: 
  #LKH solver here
  RUN mkdir -p /usr/src/LKH \
      && wget --secure-protocol=TLSv1 http://www-bs3.informatik.uni-tuebingen.de/extern/schubert/LKH-2.0.7.tgz -O LKH.tgz \
      && tar -xzf LKH.tgz -C /usr/src/LKH \
      && make -C /usr/src/LKH/LKH-2.0.7 \
      && mv /usr/src/LKH/LKH-2.0.7/LKH /usr/local/bin/ \
  