anchor.diff:  COPY . .
   RUN bash build/opt-build-local.sh $OPT
   
  -FROM ubuntu:16.04
  +FROM ubuntu:20.04
   
   LABEL maintainer="cgphelp@sanger.ac.uk" \
         uk.ac.sanger.cgp="Cancer, Ageing and Somatic Mutation, Wellcome Trust Sanger Institute" \
  
positive.code: ENV VER_VCFTOOLS="0.1.16"
  
  RUN apt-get -yq update
  RUN apt-get install -yq --no-install-recommends \
  locales \
  g++ \
  make \
  gcc \
  pkg-config \
  zlib1g-dev
  
  RUN locale-gen en_US.UTF-8
  RUN update-locale LANG=en_US.UTF-8
  
negative.code: liblzma5 \
  libncurses5 \
  p11-kit \
  libcurl3-gnutls \
  libcurl4 \
  moreutils \
  google-perftools \
  unattended-upgrades && \
  unattended-upgrade -d -v && \
  apt-get remove -yq unattended-upgrades && \
  