anchor.diff:  ///a sequence of custom output format parameters
   let outputFormat= 
       
  -    [   BlastNCBI.Parameters.OutputCustom.Query_SeqId; BlastNCBI.Parameters.OutputCustom.Subject_SeqId;BlastNCBI.Parameters.OutputCustom.Query_Length;
  -        BlastNCBI.Parameters.OutputCustom.Subject_Length;BlastNCBI.Parameters.OutputCustom.AlignmentLength;BlastNCBI.Parameters.OutputCustom.MismatchCount;
  -        BlastNCBI.Parameters.OutputCustom.IdentityCount;BlastNCBI.Parameters.OutputCustom.PositiveScoringMatchCount;BlastNCBI.Parameters.OutputCustom.Evalue;
  -        BlastNCBI.Parameters.OutputCustom.Bitscore;
  -    ] |> List.toSeq
  +    [   
  +        OutputCustom.Query_SeqId; 
  +        OutputCustom.Subject_SeqId;
  +        OutputCustom.Query_Length;
  +        OutputCustom.Subject_Length;
  +        OutputCustom.AlignmentLength;
  +        OutputCustom.MismatchCount;
  +        OutputCustom.IdentityCount;
  +        OutputCustom.PositiveScoringMatchCount;
  +        OutputCustom.Evalue;
  +        OutputCustom.Bitscore;
  +    ] 
  +        |> List.toSeq
   
   (**
   Finally, we create a `BlastParam` of the type `OutputTypeCustom` from a touple of `outputType` and `outputFormat`.
  +
   _Note: No touple required if you want to use the default output format. If this is the case,
  -just create a `BlastParam` of type `OutputType`.  
  +just create a `BlastParam` of type `OutputType`._  
   *)
   
   ///The final output format
  
positive.code: ---------------------------
  
  We have created our search database and the query we want to find. Before we can perform the actual search, we need to define the BLAST prameters.
  _Note: custom output formats can only be specified for output types `CSV`, `tabular` and `tabular with comments`. For more information, check 
  the [options for the command-line applicaions](http://www.ncbi.nlm.nih.gov/books/NBK279675/)_
  
  First, lets specify the overall output type. This will define the outline of our output. We want our output to be in tabular form, with added information
  in the form of comments.
  _Note: when not specified, the output type will be `pairwise`_
  *)
  
  ///overall outline of the output 
  
negative.code: 
  (**
  We now have everything set up to perform the BLAST search. As we are talking about proteins, we will use blastP. The parameters needed for the Wrapper function are:
  
   - path of the ncbi/bin folder
   - path and name of the search database 
   - path and name of the query
   - path and name of our output file
   - a sequence of BLAST parameters, containing any parameters additional to the above (like our customOutputFormat)
  
  _Note: in this case we can use the string `inputFile` that we used above for creating our database, as we did not specify another path or name for our database. Adjust accordingly if
  done otherwise_
  