def rename_with_prefix(self, prefix="", new_path=None, in_place=True, remove_desc=True):
        """Rename every sequence based on a prefix."""
        # Temporary path #
        if new_path is None: prefixed = self.__class__(new_temp_path())
        else:                prefixed = self.__class__(new_path)
        # Generator #
        def prefixed_iterator():
            for i,read in enumerate(self):
                read.id = prefix + read.id
                if remove_desc: read.description = ""
                yield read
        # Do it #
        prefixed.write(prefixed_iterator())
        prefixed.close()
        # Replace it #
        if in_place:
            os.remove(self.path)
            shutil.move(prefixed, self.path)
        return prefixed