def make_app(global_conf, full_stack=True, **app_conf):
    """Create a Pylons WSGI application and return it

    ``global_conf``
        The inherited configuration for this application. Normally from
        the [DEFAULT] section of the Paste ini file.

    ``full_stack``
        Whether or not this application provides a full WSGI stack (by
        default, meaning it handles its own exceptions and errors).
        Disable full_stack when this application is "managed" by
        another WSGI middleware.

    ``app_conf``
        The application's local configuration. Normally specified in the
        [app:<name>] section of the Paste ini file (where <name>
        defaults to main).
    """
    # Configure the Pylons environment
    load_environment(global_conf, app_conf)

    # The Pylons WSGI app
    app = PylonsApp()

    # CUSTOM MIDDLEWARE HERE (filtered by error handling middlewares)

    # Routing/Session/Cache Middleware
    app = RoutesMiddleware(app, config['routes.map'])
    #~ app = SessionMiddleware(app, config)
    app = CacheMiddleware(app, config)

    if asbool(full_stack):
        # Handle Python exceptions
        #~ app = ErrorHandler(app, global_conf, **config['pylons.errorware'])

        # Display error documents for 401, 403, 404 status codes (and
        # 500 when debug is disabled)
        if asbool(config['debug']):
            app = StatusCodeRedirect(app)
        else:
            app = StatusCodeRedirect(app, [400, 401, 403, 404, 500])

    # Establish the Registry for this application
    app = RegistryManager(app, streaming=True)


    # Static files (If running in production, and Apache or another web
    # server is handling this static content, remove the following 3 lines)
    javascripts_app = StaticJavascripts()
    static_app = StaticURLParser(config['pylons.paths']['static_files'])
    app = Cascade([static_app, javascripts_app, app])

    from cogen.web.async import LazyStartResponseMiddleware
    app = LazyStartResponseMiddleware(app)

    app = SessionMiddleware(app, config)

    from cogen.web.async import SynchronousInputMiddleware
    app = SynchronousInputMiddleware(app)

    return app