def dbnsfp(self):
        """dbnsfp"""

        tstart = datetime.now()

        # python ../scripts/annotate_vcfs.py -i mm13173_14.ug.target1.vcf -r 1000genomes dbsnp138 clinvar esp6500 -a ../data/1000genomes/ALL.wgs.integrated_phase1_v3.20101123.snps_indels_sv.sites.vcf.gz ../data/dbsnp138/00-All.vcf.gz ../data/dbsnp138/clinvar_00-latest.vcf.gz ../data/ESP6500/ESP6500.vcf.gz

        # command = 'python %s/cadd_dann.py -n %s -i sanity_check/checked.vcf 2>log/cadd_dann.log' % (scripts_dir, cadd_vest_cores)
        # self.shell(command)
        db = dbnsfp.Dbnsfp(self.vcf_file, settings.dbnsfp_cores)
        db.run()

        tend = datetime.now()
        execution_time = tend - tstart