def burczynski06() -> AnnData:
    """Bulk data with conditions ulcerative colitis (UC) and Crohn's disease (CD).

    The study assesses transcriptional profiles in peripheral blood mononuclear
    cells from 42 healthy individuals, 59 CD patients, and 26 UC patients by
    hybridization to microarrays interrogating more than 22,000 sequences.

    Reference
    ---------
    Burczynski et al., "Molecular classification of Crohn's disease and
    ulcerative colitis patients using transcriptional profiles in peripheral
    blood mononuclear cells"
    J Mol Diagn 8, 51 (2006). PMID:16436634.
    """
    filename = settings.datasetdir / 'burczynski06/GDS1615_full.soft.gz'
    url = 'ftp://ftp.ncbi.nlm.nih.gov/geo/datasets/GDS1nnn/GDS1615/soft/GDS1615_full.soft.gz'
    adata = sc.read(filename, backup_url=url)
    return adata