def __set_no_protein(self, hgvs_string):
        """Set a flag for no protein expected. ("p.0" or "p.0?")

        Args:
            hgvs_string (str): hgvs syntax with "p." removed
        """
        no_protein_list = ['0', '0?']  # no protein symbols
        if hgvs_string in no_protein_list:
            self.is_no_protein = True
            self.is_non_silent = True
        else:
            self.is_no_protein = False