Kliniskt relevant CTC- toxicitet som rapporterats hos < 1% (mindre vanliga) av patienterna som randomiserats till pemetrexed inkluderar supraventrikulär arytmi. ###>Clinically relevant CTC toxicities that were reported in < 1% (uncommon) of the patients that were randomly assigned to pemetrexed include supraventricular arrhythmias.