In vitro- studier visar att irbesartan primärt oxideras av cytokrom P450 enzymet CYP2C9; isoenzym CYP3A4 har försumbar effekt. ###>In vitro studies indicate that irbesartan is primarily oxidised by the cytochrome P450 enzyme CYP2C9; isoenzyme CYP3A4 has negligible effect.