Eftersom doserna i samband med degenerering av retina var inom letalt dosintervall, och ingen jämförbar effekt observerats i kliniska studier anses dessa fynd inte ha någon klinisk relevans. ###>However, because the doses implicated in retinal degeneration were in the lethal dose range, and no comparable effect has been observed in clinical studies, this finding was not considered to have clinical relevance.