Sweetgum balls contain the same active ingredient that Tamiflu contains, which is shikimic acid; It kills viruses including SARS-CoV-2
Sweetgum (Liquidambar styraciflua L.): extraction of shikimic acid coupled to dilute acid pretreatment - PMID: 20506045 - DOI: 10.1007/s12010-010-8947-7 Sweetgum (Liquidambar styraciflua L.): extraction of shikimic acid coupled to dilute acid pretreatment Liquidambar styraciflua L., also known as sweetgum, is an understory hardwood species that has widespread distribution in the southeast USA, especially in pine plantations. In addition to being a possible biorefinery feedstock, sweetgum contains shikimic acid, which is a precursor for the drug Tamiflu. Sweetgum bark was extracted with 65 degrees C water and yielded 1.7 mg/g of shikimic acid, while sweetgum de-barked wood yielded 0.2 mg/g of shikimic acid. Because shikimic acid can be extracted with water, the coupling of the phytochemical hot water extraction with dilute acid pretreatment was examined. The addition of a 65 degrees C shikimic acid extraction step coupled to pretreatment with 0.98% H(2)SO(4) at 130 degrees C for 50 min resulted in 21% and 17% increases in xylose percent recovery from bark and de-barked wood, respectively. These results indicate that, in addition to recovering a high value product, the 65 degrees C wash step also increases xylose recovery.