Favipiravir, an antiviral drug used for influenza in Japan, is currently being studied in humans for treating COVID-19 in over 30 clinical trials (as of July 31, 2020). It is not known whether it is safe or helpful for this disease.

Question: Can favipiravir help treat COVID-19?

However, safety concerns remain: hyperuricaemia, teratogenicity and QTc prolongation have not yet been adequately studied. Favipiravir may be safe and tolerable in short-term use, but more evidence is needed to assess the longer-term effects of treatment.


chloroquine and hydroxychloroquine (HCQ), which have been extensively used for the treatment of malaria with known safety and efficacy, also limit acidification of endosomes, Golgi vesicles, and lysosomes. These molecules significantly reduce SARS-CoV and SARS-CoV-2 infection in vitro.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

There is no therapeutic FDA-approved drug against SARS-CoV-2 infection, although a combination of anti-viral drugs is directly being practiced in some countries.


certain marijuana strains could possibly prevent COVID-19 infection.

Question: Can smoking cannabis (weed) help in preventing COVID-19?

An epidemic of Coronavirus Disease 2019 (COVID-19) began in December 2019 and triggered a Public Health Emergency of International Concern (PHEIC). We aimed to find risk factors for the progression of COVID-19 to help reducing the risk of critical illness and death for clinical help.


people may acquire SARS-CoV-2 through the air and after touching contaminated objects.

Question: touching a contaminated surface will not make you sick

We report here that pathogenic human coronavirus 229E remained infectious in a human lung cell culture model following at least 5 days of persistence on a range of common nonbiocidal surface materials, including polytetrafluoroethylene (Teflon; PTFE), polyvinyl chloride (PVC), ceramic tiles, glass, silicone rubber, and stainless steel.


Question: Can animals spread COVID-19?

Although a few pets presented many clinical signs indicative for a coronavirus infection, no animal tested positive for SARS-CoV-2 by RT-PCR and no antibodies against SARS-CoV-2 were detectable in their blood using an immunoprecipitation assay.


researchers think that a special strain of cannabis might potentially be a valuable tool in the fight against COVID-19.

Question: Can smoking cannabis (weed) help in preventing COVID-19?

Male, aged over 65, smoking patients might face a greater risk of developing into the critical or mortal condition and the comorbidities such as hypertension, diabetes, cardiovascular disease, and respiratory diseases could also greatly affect the prognosis of the COVID-19.


Coronaviruses are a large family of different viruses and have coexisted with humans for a long time. The leap from animals to humans, however, coronavirus is new

Question: what is the origin of COVID-19

This provides evidences strongly supporting scientific hypotheses that bats and pangolins are probable hosts for the COVID-19 virus. At the whole genome analysis level, our findings also indicate that bats are more likely the hosts for the COVID-19 virus than pangolins.


Asymptomatic COVID: Silent, but Maybe Not Harmless

Question: what is known about people that have COVID-19 without any symptoms?

Young healthy recruits often showed a mild course of COVID-19 with rapid symptom decline but were persistent SARS-CoV-2 carriers. This illustrates how asymptomatic patients may be responsible for covert viral transmission.


fear and anxiety about a new disease and what could happen can be overwhelming and cause strong emotions in adults and children.

Question: has social distancing had an impact on slowing the spread of COVID-19?

We use a simple log-linear model with intercept and trend break to evaluate whether the measures are effective preventing/slowing down the spread of the disease in Turkey.


0% Isopropyl Alcohol Is a Better Disinfectant Than 99% Isopropyl Alcohol When It Comes to COVID-19

Question: what hand sanitizers kill COVID-19?

By extrapolating effectiveness of hand sanitizers on viruses of similar structure to SARS-CoV-2, this virus should be effectively inactivated with current hand hygiene products


CT changes consistent with COVID-19 pneumonia can be observed in asymptomatic patients, as well as mild damage to the immune system.

Question: will SARS-CoV2 infected people develop immunity?

Based on animal experiments, already acquired data on other coronavirus types and plausibility assumptions, it can be assumed that seroconverted patients have an immunity of limited duration and only a very low risk of reinfection.


Understanding these immune changes may help in finding treatments that work for older COVID-19 patients, but, it may also help younger people who may have some of the same problems without knowing it.

Question: will SARS-CoV2 infected people develop immunity?

Distinguishing pre-existing and de novo antibody responses to SARS-CoV-2 will be critical for serology, seroprevalence and vaccine studies, as well as for our understanding of susceptibility to and natural course of SARS-CoV-2 infection.


chloroquine and hydroxychloroquine (HCQ), which have been extensively used for the treatment of malaria with known safety and efficacy, also limit acidification of endosomes, Golgi vesicles, and lysosomes. These molecules significantly reduce SARS-CoV and SARS-CoV-2 infection in vitro.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.


Yes, the novel coronavirus can survive on surfaces. No, it doesn't seem to matter.

Question: touching a contaminated surface will not make you sick

Inefficient human-to-human transmission of zoonotic strains may initially limit the spread of transmission, but an infection may be contracted by touching contaminated surfaces.


A lot has been written around the novel Coronavirus and how it impacts lungs, but in recent few months, experts have observed a rise in cardiac arrest cases during the pandemic.

Question: are heart complications likely in patients with COVID-19?

Cardiovascular complications were mainly observed in the confirmed COVID-19+group, consisting of heart failure (9%), palpitations/arrhythmias (3%), stroke/TIA (3%) and pulmonary hypertension (3%). Cardiovascular symptoms such as chest pain (1%), myocardial injury (1%) and pericardial effusion (1%) were also recorded.


Vitamin C may help shorten the duration and severity of colds caused by other viruses, but this is no guarantee that it will have the same effect on the coronavirus that causes COVID-19.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L).


Blood pressure drugs linked to lower Covid-19 mortality

Question: what kinds of complications related to COVID-19 are associated with hypertension?

Hypertension has been proven to be more prevalent in patients with an adverse outcome (admission in intensive care unit, use of mechanical ventilation, or death).


By curbing inflammation, the drug could help people whose immune systems have become overactive through a process called a cytokine storm, which can cause severe COVID-19 symptoms

Question: will SARS-CoV2 infected people develop immunity?

The CD4 + memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting "lung crash" until virus specific immunity develops and making it faster and prolonged. Finally, this administration could be helpful not only in already infected patients, but also before infection. In fact, people could have an immune system more ready when the contact with the Covid-19 will occur.


I think it is not really far from the truth to say that you can use extracts of ginger, garlic and many other medicinal plants to take care of the associated symptoms of viral infections, including COVID-19.

Question: Does garlic protect against covid-19

compounds derived from Allium sativum (garlic) have the potential to decrease the expression of proinflammatory cytokines and to reverse the immunological abnormalities to more acceptable levels. Allium sativum is suggested as a beneficial preventive measure before being infected with SARS-CoV-2 virus.


Question: Can children get COVID-19?

Between 1st March and 15th May 2020, 166 children (<18 years of age) presented to a specialist childrens hospital with clinical features of possible COVID-19 infection. 65 patients (39.2%) tested positive for SARS-CoV-2 virus.


wear cloth face coverings in public can stop spreading coronanvirus when social distancing is difficult. This advice is based on evidence that people with COVID-19 can transmit the COVID-19 virus before they realize they have it.

Question: Can face masks protect me from the coronavirus disease?

We find that the critical mask adherence is 5 per 100 when 80% wear face masks.


not all masks confer equal levels of protection

Question: what are the best masks for preventing infection by Covid-19?

However, low quality evidence suggests that N95 respirators protect HCWs from clinical respiratory infections.


Understanding these immune changes may help in finding treatments that work for older COVID-19 patients, but, it may also help younger people who may have some of the same problems without knowing it.

Question: will SARS-CoV2 infected people develop immunity?

Knowledge of the molecular mechanisms of viral cycles and immunity is an important prerequisite for the development of vaccination strategies and development of effective drugs.


A central player in the fight against the novel coronavirus is our immune system.

Question: will SARS-CoV2 infected people develop immunity?

The CD4 + memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting "lung crash" until virus specific immunity develops and making it faster and prolonged. Finally, this administration could be helpful not only in already infected patients, but also before infection. In fact, people could have an immune system more ready when the contact with the Covid-19 will occur.


Duo of antiviral drugs strongly inhibits SARS-CoV-2 in the lab

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

Several efforts are currently made to find a treatment for COVID-19 patients. So far, several anti-viral and immunosuppressive or immunomodulating drugs have demonstrated some efficacy on COVID-19 both in vitro and in animal models as well as in cases series.


Cell that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. Its tiny size not only increases its potential for diffusion in tissues to better neutralize the virus, but also makes it possible to administer the drug by alternative routes, including inhalation. Importantly, it does not bind to human cells -- a good sign that it won't have negative side-effects in people.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.


all hand sanitizers works against covid-19

Question: what hand sanitizers kill COVID-19?

By extrapolating effectiveness of hand sanitizers on viruses of similar structure to SARS-CoV-2, this virus should be effectively inactivated with current hand hygiene products


not all masks confer equal levels of protection

Question: what are the best masks for preventing infection by Covid-19?

We found no direct high quality evidence on whether N95 respirators are better than surgical masks for HCWs protection from SARS-CoV-2.


Favipiravir, an antiviral drug used for influenza in Japan, is currently being studied in humans for treating COVID-19 in over 30 clinical trials (as of July 31, 2020). It is not known whether it is safe or helpful for this disease.

Question: Can favipiravir help treat COVID-19?

In early research, the targeted antivirals remdesivir and favipiravir appear to benefit patients by decreasing viral replication; clinical trials suggest that remdesivir speeds recovery from COVID-19.


Face masks could be giving people Covid-19 immunity

Question: Can face masks protect me from the coronavirus disease?

Wearing medical masks or N95 masks (namely N95 respirators) can slow the virus spread and reduce the infection risk.


VITAMIN D LEVELS increase COVID-19 MORTALITY RATES

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Middle East, the recovery rate (r= 0.267) and mortality rate (r= -0.217) showed a medium correlation.


heart disease is the main cause of the death for COVID-19 patients

Question: how do people die from the coronavirus?

Respiratory failure has been cited as the major cause of death


COVID-19 is shedding new light on how viruses can kick some patient's immune system into overdrive to deadly effect in what is known as a cytokine storm syndrome.

Question: will SARS-CoV2 infected people develop immunity?

In this study, we collected blood from COVID-19 patients who have recently become virus-free and therefore were discharged, and analyzed their SARS-CoV-2-specific antibody and T cell responses. We observed SARS-CoV-2-specific humoral and cellular immunity in the patients. Both were detected in newly discharged patients, suggesting both participate in immune-mediated protection to viral infection.


While there is no evidence that infected animals can spread COVID-19 to humans, some pet owners might be concerned, understandably so, that their pet could become infected with COVID-19 and fall ill.

Question: Can animals spread COVID-19 to people?

ferrets and cats are highly susceptible to SARS-CoV-2 as infected by virus inoculation and can transmit the virus directly or indirectly by droplets or airborne routes.


budesonide, commonly prescribed in the United States under the name Pulmicort, is a good treatment for COVID-19.

Question: Is dexamethasone effective for treating COVID-19?

The recent Coronavirus [severe acute respiratory syndrome (SARS)-CoV-2]-associated multiorgan disease, called COVID-19, has high morbidity and mortality due to autoimmune destruction of the lungs stemming from the release of a storm of pro-inflammatory cytokines.


Experts anticipate some seasonal impact on the spread of the coronavirus, though the exact relationship is unclear.

Question: how does the coronavirus respond to changes in the weather

These results provide evidence for the relationship between several weather variables and the spread of COVID-19. However, the (conservatively) estimated relationships are not strong enough to seasonally control the epidemic in most locations.


The virus that causes COVID-19 appears to spread more efficiently than influenza but not as efficiently as measles, which is among the most contagious viruses known to affect people.

Question: has social distancing had an impact on slowing the spread of COVID-19?

counties where the policies have been imposed have effectively increased social distancing and have seen slowing the spread of COVID-19.


certain marijuana strains could possibly prevent COVID-19 infection.

Question: Can smoking cannabis (weed) help in preventing COVID-19?

Since many articles have reported the effect of smoking (tobacco and cannabis) and vaping in cerebrovascular and neurological systems, and considering that smokers are more prone to viral and bacterial infection compared to non-smokers, it is high time to explore the probable correlation of smoking in COVID-19 patients.


people can spread coronavirus even if they don't have symptoms (called asymptomatic) or before they have symptoms (called presymptomatic).

Question: Can face masks protect me from the coronavirus disease?

Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets.


Some people with diabetes, a disease that affects the body's ability to produce or use the hormone insulin to reduce glucose (sugar) in the blood, may be concerned about being at higher risk of getting COVID-19. However, this is a misconception.

Question: what kinds of complications related to COVID-19 are associated with diabetes

COVID-19 patients with diabetes were more likely to develop severe or critical disease conditions with more complications, and had higher incidence rates of antibiotic therapy, non-invasive and invasive mechanical ventilation, and death


immune responses to coronavirus in severely ill and critically ill patients are as strong or stronger than those of patients with milder illness.

Question: will SARS-CoV2 infected people develop immunity?

The number of these epitopes and the prevalence of the common coronaviruses suggest that a large part of the world population has some degree of specific immunity against SARS-CoV-2 already, even without having been infected by that virus.


ibuprofen may not be effective for COVID-19

Question: Are Tylenol, Advil and Motrin effective and safe to take for COVID-19 symptoms?

There are currently no approved medications or vaccines which have been claimed to be effective in COVID-19 prevention or treatment.


Our study shows that camostat mesylate blocks infection of cells with SARS-CoV-2-like particles and with authentic, patient-derived SARS-CoV-2.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


Are hydroxychloroquine and chloroquine safe? Hydroxychloroquine and chloroquine are generally considered safe when taken for conditions that they have been approved for.

Question: does hydroxychloroquine treat COVID-19?

Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.


There is currently not enough evidence to support the effectiveness of face shields for source control

Question: Can face masks protect me from the coronavirus disease?

We find that the critical mask adherence is 5 per 100 when 80% wear face masks.


Tylenol (acetaminophen) is only effective at relieving pain and fever, but Advil (ibuprofen) relieves inflammation in addition to pain and fever.

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

At this time, there is no supporting evidence to discourage the use of ibuprofen.


Coronavirus can Be Crushed By Warmer Weather

Question: how does the coronavirus respond to changes in the weather

Results indicated that temperatures had a negative linear relationship with the number of confirmed cases. The curve flattened at a threshold of 25.8 C. There is no evidence supporting that the curve declined for temperatures above 25.8 C


Question: Can animals spread COVID-19?

Although there is currently no evidence that animals play a substantial role in spreading COVID-19, CDC advises persons with suspected or confirmed COVID-19 to restrict contact with animals during their illness and to monitor any animals with confirmed SARS-CoV-2 infection and separate them from other persons and animals at home (1).


ibuprofen may not be effective for COVID-19

Question: Are Tylenol, Advil and Motrin effective and safe to take for COVID-19 symptoms?

Currently, it is not possible to discuss the efficacy and safety of a drug in the treatment of COVID-19, as most studies have just begun.


There's an evidence that pets are playing a role in spreading COVID-19

Question: Can animals spread COVID-19?

Although there is currently no evidence that animals play a substantial role in spreading COVID-19,


Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment

Question: what is the origin of COVID-19

Recent research results suggest that bats or pangolins might be the original hosts for the virus based on comparative studies using its genomic sequences.


Tylenol (acetaminophen) is only effective at relieving pain and fever, but Advil (ibuprofen) relieves inflammation in addition to pain and fever.

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

When compared with exclusive paracetamol users, no differences were observed in mortality rates or the need for respiratory support among patients using ibuprofen.


Blood Pressure Meds Could Improve Survival in COVID-19

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

The present study has found that the use of ACE inh/ARBs therapy might be associated with an increased in-hospital mortality in patients who were diagnosed with Covid-19 pneumonia.


CT changes consistent with COVID-19 pneumonia can be observed in asymptomatic patients, as well as mild damage to the immune system.

Question: will SARS-CoV2 infected people develop immunity?

we discovered evidence that SARS-CoV-2, along with related coronaviruses, used mutations to evade attack from the human immune system. Overall, we present an immunological resource for SARS-CoV-2 that could promote both therapeutic development and mechanistic research.


no clinical evidence on vitamin D in COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D deficiency that is not sufficiently treated is associated with COVID-19 risk.


Social distancing is crucial for preventing the spread of contagious illnesses such as COVID-19 (coronavirus). COVID-19 can spread through coughing, sneezing and close contact. By minimizing the amount of close contact we have with others, we reduce our chances of catching the virus and spreading it to our loved ones and within our community.

Question: has social distancing had an impact on slowing the spread of COVID-19?

To analyze the effectiveness of social distancing in the United States (U.S.).


people can spread coronavirus even if they don't have symptoms (called asymptomatic) or before they have symptoms (called presymptomatic).

Question: Can face masks protect me from the coronavirus disease?

This study 1) illustrates transmission routes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2);


in some people with severe COVID-19, the body goes rogue and attacks one of its own key immune defenses instead of the coronavirus.

Question: will SARS-CoV2 infected people develop immunity?

According to this hypothesis vaccine formulations (tetanus, diphtheria, Bordetella pertussis) could be re-administrate after the first contact with Covid-19, better before the development of respiratory severe illness and of course before full-blown ARDS (Acute Respiratory Distress Syndrome). The CD4+ memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting lung crash until virus specific immunity develops and making it faster and prolonged.


Long-term health conditions and aging weaken your immune system

Question: will SARS-CoV2 infected people develop immunity?

The number of these epitopes and the prevalence of the common coronaviruses suggest that a large part of the world population has some degree of specific immunity against SARS-CoV-2 already, even without having been infected by that virus.


young and healthy peope are in low risk with covid-19

Question: has social distancing had an impact on slowing the spread of COVID-19?

The government of different countries has adopted various policies to contain this epidemic and the most common were social distancing and lockdown. Our analysis revealed that the measures can slow down the outbreak. We can reduce the epidemic size and prolong the time to arrive at the epidemic peak by seriously following the measures suggested by the authorities.


The new coronavirus may cause migraine attacks. Headaches in general may be a symptom. Learn more about the new coronavirus, migraine, and COVID-19 symptoms.

Question: Can acetaminophen (Tylenol) treat the coronavirus disease?

COVID-19 can result in acute interstitial pneumonia, myocarditis, leucopenia (with lymphopenia) and thrombocytopenia, also seen in rheumatic diseases like lupus and Sjogrens syndrome.


Since patients treated with ACEIs and ARBS will have increased numbers of ACE2 receptors in their lungs for coronavirus S proteins to bind to, they may be at increased risk of severe disease outcomes due to SARS-CoV-2infections

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

among patients who were diagnosed with COVID-19, ACEI/ARB use was not associated with increased risk of hospital admission.


The analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus

Question: what is the origin of COVID-19

Zhou et al (1) mentioned that 'Direct contact with intermediate host animals or consumption of wild animals was suspected to be the main route of SARSCoV2 transmission.


Coronavirus can Be Crushed By Warmer Weather

Question: how does the coronavirus respond to changes in the weather

temperature is the most influential parameter that reduces the growth at the rate of 13-17 cases/day with a 1C rise in temperature.


Severe coronavirus cases may start with body aches

Question: Is a headache sign of the coronavirus disease?

Cough, fever, headache and asthenia were the most prevalent symptoms.


Tests have confirmed that two hand sanitizer formulations recommended by the World Health Organization (WHO) inactivate the virus that causes coronavirus disease 19 (COVID-19).

Question: what hand sanitizers kill COVID-19?

There is currently no vaccine for COVID-19, leaving governments and public health agencies with little defense against the virus aside from advising or enforcing best practices for virus transmission prevention, which include hand-washing, physical distancing, use of face covers, and use of effective disinfectants.


High Blood Pressure Doubles Coronavirus Death Risk

Question: what kinds of complications related to COVID-19 are associated with hypertension?

Hypertension appeared consistently as the most prevalent risk factors in COVID-19 patients.


high doses of vitamins and natural remedies can stave off COVID-19

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

The objective of this study is to determine if the components of natural origin have an anti-viral effect and which can prevent humans from infection by this coronavirus using the most reliable method is molecular docking, which used to find the interaction between studied molecules and the protein, in our case we based on the inhibitor of Coronavirus (nCoV-2019) main protease.


diabetes more than doubles your risk of dying from coronavirus.

Question: what kinds of complications related to COVID-19 are associated with diabetes

diabetes, hypertension, and cholesterol levels possess an apparent relation to COVID-19 severity.


The coronavirus can live on a surgical mask for 7 days, cloth for 2 days, and paper for 3 hours.

Question: touching a contaminated surface will not make you sick

The contaminated surface environment in hospitals plays an important role in the transmission of several key nosocomial pathogens including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp., Clostridium difficile, Acinetobacter spp., and norovirus.


a study reports the potential contribution of vitamin D deficiency to an increased risk of COVID-19 in a subset of health care workers in the UK

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Middle East, the recovery rate (r= 0.267) and mortality rate (r= -0.217) showed a medium correlation.


Cell that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. Its tiny size not only increases its potential for diffusion in tissues to better neutralize the virus, but also makes it possible to administer the drug by alternative routes, including inhalation. Importantly, it does not bind to human cells -- a good sign that it won't have negative side-effects in people.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


CT changes consistent with COVID-19 pneumonia can be observed in asymptomatic patients, as well as mild damage to the immune system.

Question: will SARS-CoV2 infected people develop immunity?

According to this hypothesis vaccine formulations (tetanus, diphtheria, Bordetella pertussis) could be re-administrate after the first contact with Covid-19, better before the development of respiratory severe illness and of course before full-blown ARDS (Acute Respiratory Distress Syndrome). The CD4+ memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting lung crash until virus specific immunity develops and making it faster and prolonged.


The pandemic coronavirus will wane with warmer weather, like some other respiratory

Question: how does the coronavirus respond to changes in the weather

COVID-19, due to its regular flu-like symptoms, is also expected to show similar seasonality and subside as the global temperatures rise in the northern hemisphere with the onset of spring


Some people with diabetes, a disease that affects the body's ability to produce or use the hormone insulin to reduce glucose (sugar) in the blood, may be concerned about being at higher risk of getting COVID-19. However, this is a misconception.

Question: what kinds of complications related to COVID-19 are associated with diabetes

Older age, diabetes and other comorbidities are reported as significant predictors of morbidity and mortality. Chronic inflammation, increased coagulation activity, immune response impairment, and potential direct pancreatic damage by SARS-CoV-2 might be among the underlying mechanisms of the association between diabetes and COVID-19.


The use of ACE inhibitors was associated with an almost 40% lower risk of COVID-19 hospitalization for the older, Medicare Advantage patients - but there was no significant difference in risk for the younger, commercially insured patients.

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

The present study has found that the use of ACE inh/ARBs therapy might be associated with an increased in-hospital mortality in patients who were diagnosed with Covid-19 pneumonia.


The coronavirus that causes COVID-19 can spread between people interacting in close proximity - for example, speaking, coughing, sneezing, or singing- even if those people do not symptoms

Question: touching a contaminated surface will not make you sick

The contaminated surface environment in hospitals plays an important role in the transmission of several key nosocomial pathogens including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp., Clostridium difficile, Acinetobacter spp., and norovirus.


Vitamin Deficiency May Raise Risk of Serious COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L).


0% Isopropyl Alcohol Is a Better Disinfectant Than 99% Isopropyl Alcohol When It Comes to COVID-19

Question: what hand sanitizers kill COVID-19?

When hand washing with soap and water is unavailable, a sufficient volume of sanitizer is necessary to ensure complete hand coverage, and compliance is critical for appropriate hand hygiene.


Can coronavirus be transmitted over surfaces? Yes.

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

COVID-19 and SARS-CoV-2 infections have, in part, successfully been treated in China by preparations from traditional Chinese medicine


Can my pet spread the coronavirus? Yes it can

Question: Can animals spread COVID-19?

Little information on the SARS-CoV-2 virus in animals is available to date.


Face masks could be giving people Covid-19 immunity

Question: Can face masks protect me from the coronavirus disease?

Together, this study suggested that medical masks are adequate for use on most social occasions, and both medical masks and N95 masks can be reused for a few days with steam decontamination between use.


Low Vitamin D Levels Tied to Odds for Severe COVID

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


the lack of Vitamin D make you more susceptible to the Covid-19 coronavirus

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


Blood Pressure Meds Could Improve Survival in COVID-19

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

Our results strongly support the recommendation that ACEI and ARB should be continued in the population and in COVID-19 positive patients, reinforcing the position of several scientific societies.


The first known cases of COVID-19 were in Wuhan, China

Question: what is the origin of COVID-19

The COVID19, which appeared to originate in China in December 2019, has spread worldwide pandemically.


Our study shows that camostat mesylate blocks infection of cells with SARS-CoV-2-like particles and with authentic, patient-derived SARS-CoV-2.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

There is no therapeutic FDA-approved drug against SARS-CoV-2 infection, although a combination of anti-viral drugs is directly being practiced in some countries.


Can dogs and cats get coronavirus ? the short answer is YES

Question: Can animals spread COVID-19?

Using data from probable cat-to-cat transmission in Wuhan, China, we estimated the basic reproduction number R0 under this scenario at 1.09 (95% confidence interval: 1.05, 1.13). This value is much lower than the R0 reported for humans and close to one, indicating that the sustained transmission between cats is unlikely to occur.


A central player in the fight against the novel coronavirus is our immune system.

Question: will SARS-CoV2 infected people develop immunity?

Based on animal experiments, already acquired data on other coronavirus types and plausibility assumptions, it can be assumed that seroconverted patients have an immunity of limited duration and only a very low risk of reinfection.


In covid-19 patients especially old people, those who had sufficient levels of vitamin D were more than 51% less likely to die than patients who were deficient.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Europe, there were no correlations for both recovery (r= 0.040) and mortality rate (r= -0.035).


The science is clear: Face masks can prevent coronavirus transmission and save lives.

Question: what are the best masks for preventing infection by Covid-19?

However, low quality evidence suggests that N95 respirators protect HCWs from clinical respiratory infections.


ARDS (acute respiratory distress syndrome) is a Common Cause of Death in Critically Ill Coronavirus Patients

Question: how do people die from the coronavirus?

Lack of personal protective equipment was cited as a common cause of death.


a person can also get the coronavirus if they touch a surface or object that has viral particles on it and then touch their mouth, nose, or eyes.

Question: touching a contaminated surface will not make you sick

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), responsible for the COVID-19 pandemic, is transmitted by person-to-person contact, via airborne droplets, or through contact with contaminated surfaces.


Consumption of alcohol will not kill the virus in the inhaled air; it will not disinfect your mouth and throat; and it will not give you any kind of protection against COVID-19.

Question: Can drinking alcohol help in preventing COVID-19?

While it remains much too early to determine precisely how alcohol use might affect risk for or progression of COVID19, any efforts to connect the dots from past alcohol research would suggest it wise for nondrinkers and lowrisk drinkers to maintain that status during this public health crisis.


Heart damage lingers in COVID-19 patients, even after recovery

Question: are heart complications likely in patients with COVID-19?

the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. Patients with heart failure or chronic kidney disease might show an excess risk


Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment

Question: what is the origin of COVID-19

While this novel coronavirus disease (covid-19) frequently induces mild diseases, it has also generated severe diseases among certain populations, including older-aged individuals with underlying diseases, such as cardiovascular disease and diabetes.


Some people with diabetes, a disease that affects the body's ability to produce or use the hormone insulin to reduce glucose (sugar) in the blood, may be concerned about being at higher risk of getting COVID-19. However, this is a misconception.

Question: what kinds of complications related to COVID-19 are associated with diabetes

Our data support the notion that diabetes should be considered as a risk factor for a rapid progression and bad prognosis of COVID-19.


people who died of COVID-19, acute respiratory failure was the leading cause of death

Question: how do people die from the coronavirus?

Lack of personal protective equipment was cited as a common cause of death.


Can Vitamin C Protect You from COVID-19?

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


people may acquire SARS-CoV-2 through the air and after touching contaminated objects.

Question: touching a contaminated surface will not make you sick

Most viruses from the respiratory tract, such as coronaviruses, influenza, SARS-CoV, or rhinovirus, can persist on surfaces for a few days.


Some people with diabetes, a disease that affects the body's ability to produce or use the hormone insulin to reduce glucose (sugar) in the blood, may be concerned about being at higher risk of getting COVID-19. However, this is a misconception.

Question: what kinds of complications related to COVID-19 are associated with diabetes

the association between DM and COVID-19-induced severe complications is still unclear


heart disease is the main cause of the death for COVID-19 patients

Question: how do people die from the coronavirus?

Compared to the recovered group, more patients in the death group exhibited characteristics of advanced age, pre-existing comorbidities, dyspnea, oxygen saturation decrease, increased WBC count, decreased lymphocytes, and elevated CRP levels.


Question: Can children get COVID-19?

Household transmission studies showed that children were rarely the index case and case studies suggested that children with COVID19 seldom caused outbreaks. However, it is highly likely that children can transmit the SARSCOV2 virus, which causes COVID19, and even asymptomatic children can have viral loads.


We know that patients with cardiovascular diseases are at particular risk of severe COVID-19 infection,

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

current evidence did not confirm the concern that ACEI/ARB exposure is harmful in patientswith COVID-19 infection. This study supports the current guidelines that discourage discontinuation of ACEIs or ARBs in COVID-19 patients and the setting of the COVID-19 pandemic


Is this right-should everyone be wearing N95 respiratory masks to stay safe from the coronavirus? In a word, no.

Question: Can face masks protect me from the coronavirus disease?

Together, this study suggested that medical masks are adequate for use on most social occasions, and both medical masks and N95 masks can be reused for a few days with steam decontamination between use.


Coronaviruses are a large family of different viruses and have coexisted with humans for a long time. The leap from animals to humans, however, coronavirus is new

Question: what is the origin of COVID-19

Recent research results suggest that bats or pangolins might be the original hosts for the virus based on comparative studies using its genomic sequences.


Face masks could be giving people Covid-19 immunity

Question: Can face masks protect me from the coronavirus disease?

It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).


simple cloth face coverings help prevent transmission of COVID-19 by people who have the virus but don't know it

Question: Can face masks protect me from the coronavirus disease?

We find that the critical mask adherence is 5 per 100 when 80% wear face masks.