While remdesivir is an antiviral agent that is being explored as a treatment for COVID-19 and is available under an Emergency Use Authorization (EUA), there are currently no drugs or other therapeutics approved by the Food and Drug Administration (FDA) to prevent or treat COVID-19. Studies are in progress to learn more.

Question: are there any clinical trials available for the coronavirus

No randomised controlled evidence is currently available for remdesivir and favipiravir.


While remdesivir is an antiviral agent that is being explored as a treatment for COVID-19 and is available under an Emergency Use Authorization (EUA), there are currently no drugs or other therapeutics approved by the Food and Drug Administration (FDA) to prevent or treat COVID-19. Studies are in progress to learn more.

Question: are there any clinical trials available for the coronavirus

On April 28, 2020, a total of 945 studies on COVID-19 have been registered in ClinicalTrials.gov; 586 studies are interventional (62.0%), the most frequent allocation scheme is the parallel group assignment (437; 74.6%), they are open-label and the most common primary purpose is the research on treatment.


While remdesivir is an antiviral agent that is being explored as a treatment for COVID-19 and is available under an Emergency Use Authorization (EUA), there are currently no drugs or other therapeutics approved by the Food and Drug Administration (FDA) to prevent or treat COVID-19. Studies are in progress to learn more.

Question: are there any clinical trials available for the coronavirus

In total, 309 trials evaluating therapeutic management options, 23 studies assessing preventive strategies and 3 studies examining both were retrieved.


While remdesivir is an antiviral agent that is being explored as a treatment for COVID-19 and is available under an Emergency Use Authorization (EUA), there are currently no drugs or other therapeutics approved by the Food and Drug Administration (FDA) to prevent or treat COVID-19. Studies are in progress to learn more.

Question: are there any clinical trials available for the coronavirus

Currently available published, peer-reviewed results mostly involve small sample sizes with study limitations restricting the interpretation of the findings.


Social Distancing Prevent the Spread of Coronavirus

Question: has social distancing had an impact on slowing the spread of COVID-19?

The government of different countries has adopted various policies to contain this epidemic and the most common were social distancing and lockdown. Our analysis revealed that the measures can slow down the outbreak. We can reduce the epidemic size and prolong the time to arrive at the epidemic peak by seriously following the measures suggested by the authorities.


Social Distancing Prevent the Spread of Coronavirus

Question: has social distancing had an impact on slowing the spread of COVID-19?

social distancing and have seen slowing the spread of COVID-19.


Social Distancing Prevent the Spread of Coronavirus

Question: has social distancing had an impact on slowing the spread of COVID-19?

Our models predict these strict social distancing measures caused a 79% and 61% reduction in the daily cases of COVID-19 across Australia and New Zealand respectively. This provides both evidence and impetus for governments considering similar measures in response to COVID-19 and other pandemics.


Social Distancing Prevent the Spread of Coronavirus

Question: has social distancing had an impact on slowing the spread of COVID-19?

The decentralized strategy is insufficient when used alone, but offers the best results when combined with the centralized one. Indeed, the (C+D) is the most efficient isolation strategy at mitigating the network superspreaders and reducing the highest node degrees to less than 10% of their initial values.


A headache isn't a common symptom of the covid-19

Question: Is a headache sign of the coronavirus disease?

However, other manifestations such as headache, abdominal pain, diarrhea, loss of taste and smell were added to the clinical spectrum, during the course of the COVID19 pandemic.


A headache isn't a common symptom of the covid-19

Question: Is a headache sign of the coronavirus disease?

Muscle injury or myalgia was the most common (19.2%, 95%CI 15.423.2%) neurologic symptom of COVID-19, followed by headache (10.9%, 95%CI 8.6213.51%);


A headache isn't a common symptom of the covid-19

Question: Is a headache sign of the coronavirus disease?

Clinical symptoms included fever (100%), cough (69.6%), expectoration (43.5%), myalgia (26.1%), headache (17.4%) and dyspnea (17.4%), and the less common symptom was diarrhea (4.3%).


A headache isn't a common symptom of the covid-19

Question: Is a headache sign of the coronavirus disease?

The aim of this manuscript is to investigate transversally Ear Nose Throat (ENT) symptoms COVID-19 infection correlated and to study the neurotropism and neuroinvasiveness of the virus in the head-neck district through the investigation of the sense of smell, taste, tearing, salivation and hearing.


A few dogs and cats living with COVID-19 patients have tested positive for the presence of SARS-CoV-2 virus.

Question: Can animals spread COVID-19?

Experimental data showed ferrets and cats are highly susceptible to SARS-CoV-2 as infected by virus inoculation and can transmit the virus directly or indirectly by droplets or airborne route.


A few dogs and cats living with COVID-19 patients have tested positive for the presence of SARS-CoV-2 virus.

Question: Can animals spread COVID-19?

There is currently no indication that feline- or canine-to-human transmission can occur, though there is rising evidence of the reverse.


A few dogs and cats living with COVID-19 patients have tested positive for the presence of SARS-CoV-2 virus.

Question: Can animals spread COVID-19?

Cellular angiotensin converting enzyme 2 (ACE2) is the receptor of SARS-CoV-2 which is identical or similar in different species of animals such as pigs, ferrets, cats, orangutans, monkeys, and humans. Moreover, a recent study predicted that dog might be secondary host during the evolution of SARS-CoV-2 from bat to human. Therefore, there is a possibility of spreading SARS-CoV-2 through domestic pets.


In the first in a series of conversations on the science of COVID-19, we learn how the hot weather is affecting the movement of the novel coronavirus.

Question: how does the coronavirus respond to changes in the weather

Preliminary observations from our team and others suggest that temperature and climatological factors could influence the spread of this novel coronavirus


In the first in a series of conversations on the science of COVID-19, we learn how the hot weather is affecting the movement of the novel coronavirus.

Question: how does the coronavirus respond to changes in the weather

Being a novel pandemic coronavirus version, it might be ongoing during summer conditions associated with higher air temperatures, low relative humidity and precipitation levels.


In the first in a series of conversations on the science of COVID-19, we learn how the hot weather is affecting the movement of the novel coronavirus.

Question: how does the coronavirus respond to changes in the weather

Temperature is the most influential parameter that reduces the growth at the rate of 13-16 cases/day with a 1{degrees}C rise in temperature


In the first in a series of conversations on the science of COVID-19, we learn how the hot weather is affecting the movement of the novel coronavirus.

Question: how does the coronavirus respond to changes in the weather

Each 1 C rise of temperature was associated with a 4.8951% (t = 2.29, p = 0.0226) decrease in the number of daily cumulative confirmed cases of COVID-19


Coronavirus may be more severe in colder months than warmer ones

Question: how does the coronavirus respond to changes in the weather

temperature is the most influential parameter that reduces the growth at the rate of 13-17 cases/day with a 1C rise in temperature.


Coronavirus may be more severe in colder months than warmer ones

Question: how does the coronavirus respond to changes in the weather

Each 1 C rise of temperature was associated with a 4.8951% (t = 2.29, p = 0.0226) decrease in the number of daily cumulative confirmed cases of COVID-19


Coronavirus may be more severe in colder months than warmer ones

Question: how does the coronavirus respond to changes in the weather

Results indicated that temperatures had a negative linear relationship with the number of confirmed cases.


Coronavirus may be more severe in colder months than warmer ones

Question: how does the coronavirus respond to changes in the weather

These results provide evidence for the relationship between several weather variables and the spread of COVID-19. However, the (conservatively) estimated relationships are not strong enough to seasonally control the epidemic in most locations.


The virus cannot survive in tropical temperatures:

Question: Does Vitamin C impact COVID-19 prevention and treatment?

Dietary supplementation has not been linked to COVID-19 prevention.


The virus cannot survive in tropical temperatures:

Question: Does Vitamin C impact COVID-19 prevention and treatment?

Although COVID-19 can be rapidly diagnosed, efficient clinical treatment of COVID-19 remains unavailable, resulting in high fatality.


The virus cannot survive in tropical temperatures:

Question: Does Vitamin C impact COVID-19 prevention and treatment?

The majority of documents encouraged the consumption of fruits, vegetables, and whole grain foods. Thirty-one percent of the guidelines highlighted the importance of minerals and vitamins such as zinc and vitamins C, A, and D to maintain a well-functioning immune system.


The virus cannot survive in tropical temperatures:

Question: Does Vitamin C impact COVID-19 prevention and treatment?

CONCLUSION The use of IV vitamin C in patients with moderate to severe COVID-19 disease may be feasible.


WH conducted a detailed survey into how coronavirus has impacted people mentally.

Question: How has the COVID-19 pandemic impacted mental health?

Psychological impact was assessed using the Impact of Event Scale-Revised (IES-R), and mental health status with the Goldberg's General Health Questionnaire (GHQ-12).


WH conducted a detailed survey into how coronavirus has impacted people mentally.

Question: How has the COVID-19 pandemic impacted mental health?

The coronavirus disease (COVID-19) pandemic has produced substantial health challenges from the perspective of both its direct health complications and the disruption to delivery of standard care for individuals with a range of acute and chronic health issues.


WH conducted a detailed survey into how coronavirus has impacted people mentally.

Question: How has the COVID-19 pandemic impacted mental health?

The socio-health emergency caused by COVID-19 may have a significant psychological impact on the population.


WH conducted a detailed survey into how coronavirus has impacted people mentally.

Question: How has the COVID-19 pandemic impacted mental health?

Various psychological problems and important consequences in terms of mental health including stress, anxiety, depression, frustration, uncertainty during COVID-19 outbreak emerged progressively.


cold weather and snow prevent the coronavirus disease

Question: how does the coronavirus respond to changes in the weather

COVID-19, due to its regular flu-like symptoms, is also expected to show similar seasonality and subside as the global temperatures rise in the northern hemisphere with the onset of spring


cold weather and snow prevent the coronavirus disease

Question: how does the coronavirus respond to changes in the weather

Temperature is the most influential parameter that reduces the growth at the rate of 13-16 cases/day with a 1{degrees}C rise in temperature


cold weather and snow prevent the coronavirus disease

Question: how does the coronavirus respond to changes in the weather

Correcting for that distributed delay and offering conservative estimates, we find a negative relationship between temperatures above 25 degrees Celsius and estimated reproduction number ([R]), with each degree Celsius associated with a 3.1% (95% CI, 1.5% to 4.8%) reduction in [R]. Higher levels of relative humidity strengthen the negative effect of temperature above 25 degrees.


cold weather and snow prevent the coronavirus disease

Question: how does the coronavirus respond to changes in the weather

meteorological conditions and air pollution, as concurring factors, impact COVID-19 transmission, using data on new confirmed cases from 219 prefecture cities from January 24 to February 29, 2020. Results revealed a kind of nonlinear dose-response relationship between temperature and coronavirus transmission


Taking a hot bath does not prevent the new coronavirus disease

Question: Does heat prevent COVID-19?

Of note, 44.12% of the detected IgM levels were dropped below the cutoff value after heating, suggesting heat inactivation can lead to false-negative results of these samples.


Taking a hot bath does not prevent the new coronavirus disease

Question: Does heat prevent COVID-19?

Since many coronaviruses are sensitive to heat, heating inactivation of samples at 56C prior to testing is considered a possible method to reduce the risk of transmission, but the effect of heating on the measurement of SARS-CoV-2 antibodies is still unclear.


Taking a hot bath does not prevent the new coronavirus disease

Question: Does heat prevent COVID-19?

It is suggested that Chinese medicine of clearing heat and removing toxin should be used to prevent the uninfected people from COVID-19, and intervene in the early stage of the disease and control the development of it to be severe by inhibiting the cytokine storm.


Taking a hot bath does not prevent the new coronavirus disease

Question: Does heat prevent COVID-19?

Our results indicate that heat inactivation of serum at 56C for 30 minutes interferes with the immunoanalysis of antibodies to SARS-CoV-2. Heat inactivation prior to immunoanalysis is not recommended, and the possibility of false-negative results should be considered if the sample was pre-inactivated by heating.


male patients with other COVID-19 mortality risk factors, such as older age and additional comorbidities, had an increased risk of death.

Question: how do people die from the coronavirus?

The cause of most deaths has been acute pneumonia.


male patients with other COVID-19 mortality risk factors, such as older age and additional comorbidities, had an increased risk of death.

Question: how do people die from the coronavirus?

Respiratory failure has been cited as the major cause of death


male patients with other COVID-19 mortality risk factors, such as older age and additional comorbidities, had an increased risk of death.

Question: how do people die from the coronavirus?

Compared to the recovered group, more patients in the death group exhibited characteristics of advanced age, pre-existing comorbidities, dyspnea, oxygen saturation decrease, increased WBC count, decreased lymphocytes, and elevated CRP levels.


While some children and infants have been sick with COVID-19, adults make up most of the known cases to date.

Question: what are the mortality rates overall and in specific populations

We estimate an overall infection fatality rate of 1.29% (95% credible interval [CrI] 0.89 - 2.01), as well as large differences by age, with a low infection fatality rate of 0.05% for under 60 year old (CrI 0-.19) and a substantially higher 4.25% (CrI 3.01-6.39) for people above 60 years of age.


While some children and infants have been sick with COVID-19, adults make up most of the known cases to date.

Question: what are the mortality rates overall and in specific populations

Mortality was significantly associated with older age, lower body mass index, chronic renal disease, higher Sequential Organ Failure Assessment score, lower PaO2/FIO2 ratio, higher D-dimer, higher C-reactive protein, and receipt of mechanical ventilation, vasopressors, renal replacement therapy, or vasodilator therapy.


While some children and infants have been sick with COVID-19, adults make up most of the known cases to date.

Question: what are the mortality rates overall and in specific populations

The COVID-19 population-level mortality rate (per 100,000 person-years) increased with age: from 0.1 deaths among 30-39 year olds to 9.5 deaths among 80 year olds.


While some children and infants have been sick with COVID-19, adults make up most of the known cases to date.

Question: what are the mortality rates overall and in specific populations

A confirmed SARS-CoV-2 infection substantially increased the probability of death across all patient groups, ranging from nine (6 to 15) times the population mortality in 35-year old infected females to a 53-fold increase (46 to 59) for 95 year old infected males. The highest relative risks were observed among males and older patients.


Question: Can favipiravir help treat COVID-19?

Herein, we examine the effects of Favipiravir (FPV) versus Lopinavir (LPV)/ritonavir (RTV) for the treatment of COVID-19.


Question: Can favipiravir help treat COVID-19?

currently, appropriate treatment for patients with COVID19 is an ACE2 inhibitor and a clinical problem reducing agent such as favipiravir in addition to hydroxychloroquine and corticosteroids.


Question: Can favipiravir help treat COVID-19?

Twenty-nine studies were identified as potential sources of evidence of the clinical safety of favipiravir.


Question: Can favipiravir help treat COVID-19?

Our study reports the promising effectiveness of favipiravir for treating COVID-19 patients.


The rationale for using vitamin D is based largely on immunomodulatory effects that could potentially protect against COVID-19 infection or decrease the severity of illness

Question: Does Vitamin D impact COVID-19 prevention and treatment?

The severity of coronavirus 2019 infection (COVID-19) is determined by the presence of pneumonia, severe acute respiratory distress syndrome (SARS-CoV-2), myocarditis, microvascular thrombosis and/or cytokine storms, all of which involve underlying inflammation.


The rationale for using vitamin D is based largely on immunomodulatory effects that could potentially protect against COVID-19 infection or decrease the severity of illness

Question: Does Vitamin D impact COVID-19 prevention and treatment?

a small reverse correlation between mortality rate and vitamin D status was observed throughout the globe (r= -0.177). In Asia, a medium direct correlation was observed for recovery rate (r= 0.317) and a significant reveres correlation for mortality rate (r= -0.700) with vitamin D status in such patients.


The rationale for using vitamin D is based largely on immunomodulatory effects that could potentially protect against COVID-19 infection or decrease the severity of illness

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Europe, there were no correlations for both recovery (r= 0.040) and mortality rate (r= -0.035).


The rationale for using vitamin D is based largely on immunomodulatory effects that could potentially protect against COVID-19 infection or decrease the severity of illness

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D dose was not significantly associated with testing positive for COVID-19.


Question: what is the origin of COVID-19

Although to date it is considered that Covid19 originates from bats (96.2% overall genome sequence identity) (1), the type of intermediate animals that caused the transmission to humans remains unknown (2-4).


Although to date it is considered that Covid19 originates from bats (96.2% overall genome sequence identity) (1), the type of intermediate animals that caused the transmission to humans remains unknown (2-4)

Question: what is the origin of COVID-19

Covid19 infection began in Wuhan (Hubei, China) in December, 2019.


Although to date it is considered that Covid19 originates from bats (96.2% overall genome sequence identity) (1), the type of intermediate animals that caused the transmission to humans remains unknown (2-4)

Question: what is the origin of COVID-19

However, the source(s) and transmission routine(s) of SARSCoV2 remain elusive' (1).


Although to date it is considered that Covid19 originates from bats (96.2% overall genome sequence identity) (1), the type of intermediate animals that caused the transmission to humans remains unknown (2-4)

Question: what is the origin of COVID-19

This paper investigates the COVID-19 virus origin by using artificial intelligence (AI) and raw genomic sequences of the virus.


the covid-19 is a us biological weapon to reduce the planet's population

Question: does hydroxychloroquine treat COVID-19?

the use of hydroxychloroquine alone was associated with increased mortality in COVID-19 patients.


the covid-19 is a us biological weapon to reduce the planet's population

Question: does hydroxychloroquine treat COVID-19?

Among patients with COVID-19, the use of HCQ could significantly shorten TTCR and promote the absorption of pneumonia.


the covid-19 is a us biological weapon to reduce the planet's population

Question: does hydroxychloroquine treat COVID-19?

The available evidence suggests that CQ or HCQ does not improve clinical outcomes in COVID-19.


the covid-19 is a us biological weapon to reduce the planet's population

Question: does hydroxychloroquine treat COVID-19?

The odds of mortality were significantly higher in patients treated with Hydroxychloroquine + Azithromycin than supportive care alone [2.34 (95% CI: 1.63, 3.34); I2 = 0%]. A pooled analysis of recently published studies suggests no additional benefit for reducing mortality in COVID-19 patients when Hydroxychloroquine is given as add-on to the standard care.


Hydroxychloroquine, by itself or with azithromycin, did not improve the clinical status of patients with mild to moderate COVID-19

Question: does hydroxychloroquine treat COVID-19?

patients treated with HCQ at the time of early hospital recovered faster than those who treated later or taken as second line choose for their obvious shorter hospitalization time.


Hydroxychloroquine, by itself or with azithromycin, did not improve the clinical status of patients with mild to moderate COVID-19

Question: does hydroxychloroquine treat COVID-19?

Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.


Hydroxychloroquine, by itself or with azithromycin, did not improve the clinical status of patients with mild to moderate COVID-19

Question: does hydroxychloroquine treat COVID-19?

Among patients with COVID-19, the use of HCQ could significantly shorten TTCR and promote the absorption of pneumonia.


Hydroxychloroquine, by itself or with azithromycin, did not improve the clinical status of patients with mild to moderate COVID-19

Question: does hydroxychloroquine treat COVID-19?

mortality rate was increased when the treatment was conducted with hydroxychloroquine.


Can I take any vitamins or supplements to prevent COVID-19? In fact, taking too much vitamin C can lead to upset stomach, diarrhea, and reduce the effectiveness of some medications. If you want to take a supplement of vitamin C, I'm not opposed and it may even offer some benefits. Just keep in mind that more isn't always more. Take a food-first approach by enjoying a diet rich in fruits and vegetables.

Question: Can I take any vitamins or supplements to prevent COVID-19?

Here, we review theoretical mechanisms and evidence related to efficacy and safety of select supplements in the setting of COVID-19, including vitamin C, vitamin D, zinc, elderberry, and silver.


Can I take any vitamins or supplements to prevent COVID-19? In fact, taking too much vitamin C can lead to upset stomach, diarrhea, and reduce the effectiveness of some medications. If you want to take a supplement of vitamin C, I'm not opposed and it may even offer some benefits. Just keep in mind that more isn't always more. Take a food-first approach by enjoying a diet rich in fruits and vegetables.

Question: Can I take any vitamins or supplements to prevent COVID-19?

Evidence evaluating these supplements in COVID-19 patients is lacking, and providers and patients should not rely on dietary supplements to prevent or treat COVID-19.


The winter can spread the coronavirus transmission as in winter months, people may cluster together more indoors, increasing the number of folks at risk of becoming infection by someone who's contagious.

Question: how does the coronavirus respond to changes in the weather

Being a novel pandemic coronavirus version, it might be ongoing during summer conditions associated with higher air temperatures, low relative humidity and precipitation levels.


The winter can spread the coronavirus transmission as in winter months, people may cluster together more indoors, increasing the number of folks at risk of becoming infection by someone who's contagious.

Question: how does the coronavirus respond to changes in the weather

Correcting for that distributed delay and offering conservative estimates, we find a negative relationship between temperatures above 25 degrees Celsius and estimated reproduction number ([R]), with each degree Celsius associated with a 3.1% (95% CI, 1.5% to 4.8%) reduction in [R]. Higher levels of relative humidity strengthen the negative effect of temperature above 25 degrees.


The winter can spread the coronavirus transmission as in winter months, people may cluster together more indoors, increasing the number of folks at risk of becoming infection by someone who's contagious.

Question: how does the coronavirus respond to changes in the weather

temperature is the most influential parameter that reduces the growth at the rate of 13-17 cases/day with a 1C rise in temperature.


The winter can spread the coronavirus transmission as in winter months, people may cluster together more indoors, increasing the number of folks at risk of becoming infection by someone who's contagious.

Question: how does the coronavirus respond to changes in the weather

the temperature changes retarded the growth rate and found that -6.28{degrees}C and +14.51{degrees}C temperature is the favorable range for COVID-19 growth


Vitamin C infusion is not approved as a standard treatment for SARS-CoV-2 and thus was not part of the hospital's COVID-19 treatment regimen.

Question: Can vitamin C treat COVID-19?

So far, there is scarce evidence for the current treatment options available for COVID-19.


Vitamin C infusion is not approved as a standard treatment for SARS-CoV-2 and thus was not part of the hospital's COVID-19 treatment regimen.

Question: Can vitamin C treat COVID-19?

Some clinical trials have identified vitamin C (VC) as a potent compound pneumonia management.


Vitamin C infusion is not approved as a standard treatment for SARS-CoV-2 and thus was not part of the hospital's COVID-19 treatment regimen.

Question: Can vitamin C treat COVID-19?

The inpatient mortality rate in this series was 12% with 17.6% rates of intubation and mechanical ventilation. We noted a significant decrease in inflammatory markers, including ferritin and D-dimer, and a trend to decreasing FiO2 requirements, after vitamin C administration.


Vitamin C infusion is not approved as a standard treatment for SARS-CoV-2 and thus was not part of the hospital's COVID-19 treatment regimen.

Question: Can vitamin C treat COVID-19?

The use of IV vitamin C in patients with moderate to severe COVID-19 disease may be feasible.


But there is a lot of competition, with more than 200 coronavirus vaccine candidates under investigation around the world. Two dozen are undergoing testing in humans, and six are in phase 3

Question: What vaccine candidates are being tested for Covid-19?

Currently, there is no vaccine or therapeutic available for this disease.


But there is a lot of competition, with more than 200 coronavirus vaccine candidates under investigation around the world. Two dozen are undergoing testing in humans, and six are in phase 3

Question: What vaccine candidates are being tested for Covid-19?

At this time, no vaccine is available to control further dissemination of the disease.


But there is a lot of competition, with more than 200 coronavirus vaccine candidates under investigation around the world. Two dozen are undergoing testing in humans, and six are in phase 3

Question: What vaccine candidates are being tested for Covid-19?

Vaccines for this deadly virus are currently under development and many drugs used for other indications have been repurposed and investigated for prophylaxis and treatment of COVID 19.


But there is a lot of competition, with more than 200 coronavirus vaccine candidates under investigation around the world. Two dozen are undergoing testing in humans, and six are in phase 3

Question: What vaccine candidates are being tested for Covid-19?

Currently there is no known vaccine or specific antiviral treatment for COVID-19


taking medication to lower fever, such as paracetamol (Tylenol) and ibuprofen (Advil), should be avoided when sick with the new coronavirus

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

At this time, there is no supporting evidence to discourage the use of ibuprofen.


taking medication to lower fever, such as paracetamol (Tylenol) and ibuprofen (Advil), should be avoided when sick with the new coronavirus

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

For NSAIDs, there is no clear scientific evidence linking ibuprofen and other NSAIDs to worsening of COVID-19;


taking medication to lower fever, such as paracetamol (Tylenol) and ibuprofen (Advil), should be avoided when sick with the new coronavirus

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

There are clearly COVID-19 cases where NSAIDs should not be used, but there is no strong evidence that NSAIDs must be avoided in all patients with COVID-19;


taking medication to lower fever, such as paracetamol (Tylenol) and ibuprofen (Advil), should be avoided when sick with the new coronavirus

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

Ibuprofen is an over-the-counter medication that is used widely for the treatment of pain and fever during COVID-19 pandemic.


Hand sanitizer can kill coronavirus-but that doesn't mean it should be your first defense.

Question: what hand sanitizers kill COVID-19?

There is currently no vaccine for COVID-19, leaving governments and public health agencies with little defense against the virus aside from advising or enforcing best practices for virus transmission prevention, which include hand-washing, physical distancing, use of face covers, and use of effective disinfectants.


Hand sanitizer can kill coronavirus-but that doesn't mean it should be your first defense.

Question: what hand sanitizers kill COVID-19?

The index of India has remained very low (161) so far, mainly due to early implementation of social lockdown, social distancing, and sanitizing hands.


Hand sanitizer can kill coronavirus-but that doesn't mean it should be your first defense.

Question: what hand sanitizers kill COVID-19?

By extrapolating effectiveness of hand sanitizers on viruses of similar structure to SARS-CoV-2, this virus should be effectively inactivated with current hand hygiene products


Hand sanitizer can kill coronavirus-but that doesn't mean it should be your first defense.

Question: what hand sanitizers kill COVID-19?

Efficient SARS-CoV-2 inactivation was demonstrated for all tested alcohol-based disinfectants. These findings show the successful inactivation of SARS-CoV-2 for the first time and provide confidence in its use for the control of COVID-19.


Whilethe lopinavir-ritonavir-, hydroxychloroquine sulfate-, or emtricitabine-tenofovirtreated group exhibited lower overall clinical scores than the phosphate-buffered saline (PBS)-treated control group, the virus titers in nasal washes, stool specimens,and respiratory tissues were similar between all three antiviral-candidate-treated groups and the PBS-treated control group.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

At this point, the data here presented on hydroxychloroquine either alone or combined with azithromycin (together with previously reported in vivo data in macaques and ferrets) provide no scientific basis for further use of the drug in humans.


Whilethe lopinavir-ritonavir-, hydroxychloroquine sulfate-, or emtricitabine-tenofovirtreated group exhibited lower overall clinical scores than the phosphate-buffered saline (PBS)-treated control group, the virus titers in nasal washes, stool specimens,and respiratory tissues were similar between all three antiviral-candidate-treated groups and the PBS-treated control group.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

At this point, the data here presented on hydroxychloroquine either alone or combined with azithromycin (together with previously reported in vivo data in macaques and ferrets) provide no scientific basis for further use of the drug in humans.


Whilethe lopinavir-ritonavir-, hydroxychloroquine sulfate-, or emtricitabine-tenofovirtreated group exhibited lower overall clinical scores than the phosphate-buffered saline (PBS)-treated control group, the virus titers in nasal washes, stool specimens,and respiratory tissues were similar between all three antiviral-candidate-treated groups and the PBS-treated control group.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


Whilethe lopinavir-ritonavir-, hydroxychloroquine sulfate-, or emtricitabine-tenofovirtreated group exhibited lower overall clinical scores than the phosphate-buffered saline (PBS)-treated control group, the virus titers in nasal washes, stool specimens,and respiratory tissues were similar between all three antiviral-candidate-treated groups and the PBS-treated control group.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

Several efforts are currently made to find a treatment for COVID-19 patients. So far, several anti-viral and immunosuppressive or immunomodulating drugs have demonstrated some efficacy on COVID-19 both in vitro and in animal models as well as in cases series.


As cold weather arrives, the number of covid-19 cases increases

Question: how does the coronavirus respond to changes in the weather

These results provide evidence for the relationship between several weather variables and the spread of COVID-19. However, the (conservatively) estimated relationships are not strong enough to seasonally control the epidemic in most locations.


As cold weather arrives, the number of covid-19 cases increases

Question: how does the coronavirus respond to changes in the weather

the temperature changes retarded the growth rate and found that -6.28{degrees}C and +14.51{degrees}C temperature is the favorable range for COVID-19 growth


As cold weather arrives, the number of covid-19 cases increases

Question: how does the coronavirus respond to changes in the weather

We show that the delay between exposure and detection of infection complicates the estimation of weather impact on COVID-19 transmission, potentially explaining significant variability in results to-date


As cold weather arrives, the number of covid-19 cases increases

Question: how does the coronavirus respond to changes in the weather

Temperature is the most influential parameter that reduces the growth at the rate of 13-16 cases/day with a 1{degrees}C rise in temperature


Wearing a medical mask causes you to breathe in more carbon dioxide

Question: Can wearing masks help in preventing the spread of the coronavirus disease?

Face masks are an avenue to curb the spread of coronavirus, but few people in Western societies wear face masks.


Wearing a medical mask causes you to breathe in more carbon dioxide

Question: Can wearing masks help in preventing the spread of the coronavirus disease?

This study 1) illustrates transmission routes of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); 2) addresses controversies surrounding the mask from perspectives of attitude, effectiveness, and necessity of wearing the mask with evidence that the use of mask would effectively interrupt the transmission of infectious diseases in both hospital settings and community settings; and 3) provides suggestion that the public should wear the mask during COVID-19 pandemic according to local context.


Wearing a medical mask causes you to breathe in more carbon dioxide

Question: Can wearing masks help in preventing the spread of the coronavirus disease?

Evidence that face masks provide effective protection against respiratory infections in the community is scarce. However, face masks are widely used by health workers as part of droplet precautions when caring for patients with respiratory infections. It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).


Wearing a medical mask causes you to breathe in more carbon dioxide

Question: Can wearing masks help in preventing the spread of the coronavirus disease?

Wearing medical masks or N95 masks (namely N95 respirators) can slow the virus spread and reduce the infection risk.


There is no scientific evidence to say that masks are effective

Question: what are the best masks for preventing infection by Covid-19?

However, wearing N95 respirators can prevent 73 more (95% CI 46-91) clinical respiratory infections per 1000 HCWs compared to surgical masks (2 RCTs; 2594 patients; low quality of evidence).


There is no scientific evidence to say that masks are effective

Question: what are the best masks for preventing infection by Covid-19?

Ma's research shows N95 masks, medical masks, even homemade masks could block at least 90% of the virus in aerosols


There is no scientific evidence to say that masks are effective

Question: what are the best masks for preventing infection by Covid-19?

The WHO, ECDC and CDC have issued conflicting guidelines on the use of respiratory filters (N95) by HCWs.


There is no scientific evidence to say that masks are effective

Question: what are the best masks for preventing infection by Covid-19?

Respirators such as filtering face piece (FFP) 2 masks were designed to protect HCWs, while surgical masks were originally intended to protect patients (e.g., during surgery). Nevertheless, high quality standard surgical masks (type II/IIR according to European Norm EN 14683) appear to be as effective as FFP2 masks in preventing droplet-associated viral infections of HCWs as reported from influenza or SARS.


The study, of 507 patients with confirmed COVID-19, found there was no significant difference in clinical outcome with the addition of hydroxychloroquine, either with or without azithromycin.

Question: does hydroxychloroquine treat COVID-19?

The available evidence suggests that CQ or HCQ does not improve clinical outcomes in COVID-19.


The study, of 507 patients with confirmed COVID-19, found there was no significant difference in clinical outcome with the addition of hydroxychloroquine, either with or without azithromycin.

Question: does hydroxychloroquine treat COVID-19?

the use of hydroxychloroquine alone was associated with increased mortality in COVID-19 patients.


The study, of 507 patients with confirmed COVID-19, found there was no significant difference in clinical outcome with the addition of hydroxychloroquine, either with or without azithromycin.

Question: does hydroxychloroquine treat COVID-19?

The odds of mortality were significantly higher in patients treated with Hydroxychloroquine + Azithromycin than supportive care alone [2.34 (95% CI: 1.63, 3.34); I2 = 0%]. A pooled analysis of recently published studies suggests no additional benefit for reducing mortality in COVID-19 patients when Hydroxychloroquine is given as add-on to the standard care.


The study, of 507 patients with confirmed COVID-19, found there was no significant difference in clinical outcome with the addition of hydroxychloroquine, either with or without azithromycin.

Question: does hydroxychloroquine treat COVID-19?

Since COVID-19 outbreak, various agents have been tested but no proven effective therapies have been identified.


Vitamin D can keep exposure to COVID-19 from becoming an infection that can cause you and other people harm

Question: Does Vitamin D impact COVID-19 prevention and treatment?

The severity of coronavirus 2019 infection (COVID-19) is determined by the presence of pneumonia, severe acute respiratory distress syndrome (SARS-CoV-2), myocarditis, microvascular thrombosis and/or cytokine storms, all of which involve underlying inflammation.


Vitamin D can keep exposure to COVID-19 from becoming an infection that can cause you and other people harm

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Europe, there were no correlations for both recovery (r= 0.040) and mortality rate (r= -0.035).


Vitamin D can keep exposure to COVID-19 from becoming an infection that can cause you and other people harm

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D dose was not significantly associated with testing positive for COVID-19.


Vitamin D can keep exposure to COVID-19 from becoming an infection that can cause you and other people harm

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


no studies have investigated the effect of vitamin D supplements or vitamin D deficiency on the risk of contracting the new coronavirus

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D dose was not significantly associated with testing positive for COVID-19.


no studies have investigated the effect of vitamin D supplements or vitamin D deficiency on the risk of contracting the new coronavirus

Question: Does Vitamin D impact COVID-19 prevention and treatment?

In Middle East, the recovery rate (r= 0.267) and mortality rate (r= -0.217) showed a medium correlation.


no studies have investigated the effect of vitamin D supplements or vitamin D deficiency on the risk of contracting the new coronavirus

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D deficiency that is not sufficiently treated is associated with COVID-19 risk.


no studies have investigated the effect of vitamin D supplements or vitamin D deficiency on the risk of contracting the new coronavirus

Question: Does Vitamin D impact COVID-19 prevention and treatment?

ecological investigation on 51 countries including 408,748 participants, analyses indicated no correlation between vitamin D levels and recovery rate (r= 0.041) as well as mortality rate (r=-0.073) globally.


hydroxychloroquine may cause direct myocardial toxicity and worsen cardiomyopathy, a problem that can lead to heart failure.

Question: are heart complications likely in patients with COVID-19?

The clinical evidence in our study suggested that myocardial injury is more likely related to systemic consequences rather than direct damage by the 2019 novel coronavirus. The elevation in cardiac markers was probably due to secondary and systemic consequences and can be considered as the warning sign for recent adverse clinical outcomes of the patients


hydroxychloroquine may cause direct myocardial toxicity and worsen cardiomyopathy, a problem that can lead to heart failure.

Question: are heart complications likely in patients with COVID-19?

Cardiovascular complications were mainly observed in the confirmed COVID-19+group, consisting of heart failure (9%), palpitations/arrhythmias (3%), stroke/TIA (3%) and pulmonary hypertension (3%). Cardiovascular symptoms such as chest pain (1%), myocardial injury (1%) and pericardial effusion (1%) were also recorded.


hydroxychloroquine may cause direct myocardial toxicity and worsen cardiomyopathy, a problem that can lead to heart failure.

Question: are heart complications likely in patients with COVID-19?

Myocardial injury is significantly associated with fatal outcome of COVID-19, while the prognosis of patients with underlying CVD but without myocardial injury is relatively favorable. Myocardial injury is associated with cardiac dysfunction and arrhythmias. Inflammation may be a potential mechanism for myocardial injury.


hydroxychloroquine may cause direct myocardial toxicity and worsen cardiomyopathy, a problem that can lead to heart failure.

Question: are heart complications likely in patients with COVID-19?

the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. Patients with heart failure or chronic kidney disease might show an excess risk


Vitamin D deficiency may be linked to COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L).


Vitamin D deficiency may be linked to COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

A significant negative correlation (p=0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries.


Vitamin D deficiency may be linked to COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


Vitamin D deficiency may be linked to COVID-19

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D deficiency that is not sufficiently treated is associated with COVID-19 risk.


Can chloroquine treat coronavirus? There's some very early science, but not a lot, to back the idea that this antimalarial drug might have promise against COVID-19.

Question: does hydroxychloroquine treat COVID-19?

Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.


Can chloroquine treat coronavirus? There's some very early science, but not a lot, to back the idea that this antimalarial drug might have promise against COVID-19.

Question: does hydroxychloroquine treat COVID-19?

the use of hydroxychloroquine alone was associated with increased mortality in COVID-19 patients.


Can chloroquine treat coronavirus? There's some very early science, but not a lot, to back the idea that this antimalarial drug might have promise against COVID-19.

Question: does hydroxychloroquine treat COVID-19?

There is theoretical, experimental, preclinical and clinical evidence of the effectiveness of chloroquine in patients affected with COVID-19.


Can chloroquine treat coronavirus? There's some very early science, but not a lot, to back the idea that this antimalarial drug might have promise against COVID-19.

Question: does hydroxychloroquine treat COVID-19?

Preliminary clinical evidence from China and France showed significant virological and clinical benefit in HCQ-treated patients, while other studies, mostly including critically ill patients, did not show favorable results.


Social distancing should be practiced in combination with other everyday preventive actions to reduce the spread of COVID-19, including wearing masks, avoiding touching your face with unwashed hands, and frequently washing your hands with soap and water for at least 20 seconds.

Question: has social distancing had an impact on slowing the spread of COVID-19?

The government of different countries has adopted various policies to contain this epidemic and the most common were social distancing and lockdown. Our analysis revealed that the measures can slow down the outbreak. We can reduce the epidemic size and prolong the time to arrive at the epidemic peak by seriously following the measures suggested by the authorities.


Social distancing should be practiced in combination with other everyday preventive actions to reduce the spread of COVID-19, including wearing masks, avoiding touching your face with unwashed hands, and frequently washing your hands with soap and water for at least 20 seconds.

Question: has social distancing had an impact on slowing the spread of COVID-19?

The decentralized strategy is insufficient when used alone, but offers the best results when combined with the centralized one. Indeed, the (C+D) is the most efficient isolation strategy at mitigating the network superspreaders and reducing the highest node degrees to less than 10% of their initial values.


Social distancing should be practiced in combination with other everyday preventive actions to reduce the spread of COVID-19, including wearing masks, avoiding touching your face with unwashed hands, and frequently washing your hands with soap and water for at least 20 seconds.

Question: has social distancing had an impact on slowing the spread of COVID-19?

stronger social distancing, e.g., cutting 75% of social ties, can reduce the outbreak by 75% for the C isolation, by 33% for the D isolation, and by 87% for the (C+D) isolation strategy.


Social distancing should be practiced in combination with other everyday preventive actions to reduce the spread of COVID-19, including wearing masks, avoiding touching your face with unwashed hands, and frequently washing your hands with soap and water for at least 20 seconds.

Question: has social distancing had an impact on slowing the spread of COVID-19?

social distancing is associated with a statistically-significant reduction in the doubling rate for all but three states.


lopinavir (LPV), ritonavir, chloroquine, favipiravir, and remdesivir drugs can cure and treat covid-19

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


lopinavir (LPV), ritonavir, chloroquine, favipiravir, and remdesivir drugs can cure and treat covid-19

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.


lopinavir (LPV), ritonavir, chloroquine, favipiravir, and remdesivir drugs can cure and treat covid-19

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


lopinavir (LPV), ritonavir, chloroquine, favipiravir, and remdesivir drugs can cure and treat covid-19

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

Thus, our goal is to test the most active antivirals identified in adequate animal models infected with SARS-CoV-2, to add more information about possible in vivo efficacy. In turn, successful antivirals could be tested in clinical trials as treatments for infected patients, but also as pre-exposure prophylaxis to avoid novel infections until an effective and safe vaccine is developed.


Patients with a history of a bone marrow transplant are at higher risk, too, because their immune system would be suppressed long-term.

Question: will SARS-CoV2 infected people develop immunity?

The number of these epitopes and the prevalence of the common coronaviruses suggest that a large part of the world population has some degree of specific immunity against SARS-CoV-2 already, even without having been infected by that virus.


Patients with a history of a bone marrow transplant are at higher risk, too, because their immune system would be suppressed long-term.

Question: will SARS-CoV2 infected people develop immunity?

Based on animal experiments, already acquired data on other coronavirus types and plausibility assumptions, it can be assumed that seroconverted patients have an immunity of limited duration and only a very low risk of reinfection.


Patients with a history of a bone marrow transplant are at higher risk, too, because their immune system would be suppressed long-term.

Question: will SARS-CoV2 infected people develop immunity?

The number of these epitopes and the prevalence of the common coronaviruses suggest that a large part of the world population has some degree of specific immunity against SARS-CoV-2 already, even without having been infected by that virus.


Patients with a history of a bone marrow transplant are at higher risk, too, because their immune system would be suppressed long-term.

Question: will SARS-CoV2 infected people develop immunity?

Knowledge of the molecular mechanisms of viral cycles and immunity is an important prerequisite for the development of vaccination strategies and development of effective drugs.


Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

There is no therapeutic FDA-approved drug against SARS-CoV-2 infection, although a combination of anti-viral drugs is directly being practiced in some countries.


Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

At this point, the data here presented on hydroxychloroquine either alone or combined with azithromycin (together with previously reported in vivo data in macaques and ferrets) provide no scientific basis for further use of the drug in humans.


Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

Several efforts are currently made to find a treatment for COVID-19 patients. So far, several anti-viral and immunosuppressive or immunomodulating drugs have demonstrated some efficacy on COVID-19 both in vitro and in animal models as well as in cases series.


Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients.

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.


Vitamin B "should be assessed" as a possible "adjunct to current treatments" for COVID-19

Question: Does Vitamin C impact COVID-19 prevention and treatment?

Although COVID-19 can be rapidly diagnosed, efficient clinical treatment of COVID-19 remains unavailable, resulting in high fatality.


Vitamin B "should be assessed" as a possible "adjunct to current treatments" for COVID-19

Question: Does Vitamin C impact COVID-19 prevention and treatment?

Some nutrients are actively involved in the proper functioning and strengthening of the human immune system against viral infections including dietary protein, omega-3 fatty acids, vitamin A, vitamin D, vitamin E, vitamin B1, vitamin B6, vitamin B12, vitamin C, iron, zinc, and selenium. Few studies were done on the effect of dietary components on prevention of COVID-19, but supplementation with these nutrients may be effective in improving the health status of patients with viral infections.


Vitamin B "should be assessed" as a possible "adjunct to current treatments" for COVID-19

Question: Does Vitamin C impact COVID-19 prevention and treatment?

We identified a total of 17 patients who received IV vitamin C for COVID-19. The inpatient mortality rate in this series was 12% with 17.6% rates of intubation and mechanical ventilation. We noted a significant decrease in inflammatory markers, including ferritin and D-dimer, and a trend to decreasing FiO2 requirements, after vitamin C administration.


Vitamin B "should be assessed" as a possible "adjunct to current treatments" for COVID-19

Question: Does Vitamin C impact COVID-19 prevention and treatment?

The majority of documents encouraged the consumption of fruits, vegetables, and whole grain foods. Thirty-one percent of the guidelines highlighted the importance of minerals and vitamins such as zinc and vitamins C, A, and D to maintain a well-functioning immune system.


Question: How dangerous is COVID-19?

During quarantine due to the COVID-19, home risks to become a very dangerous place for victims of domestic violence.


Question: How dangerous is COVID-19?

Given the scope and speed of the spread, the COVID-19 pandemic is not only complex but dangerous.


Question: How dangerous is COVID-19?

Covid-19 is a disease caused by a new coronavirus presenting a variability of flu-like symptoms including fever, cough, myalgia and fatigue; in severe cases, patients develop pneumonia, acute respiratory distress syndrome, sepsis and septic shock, that can result in their death.


Question: How dangerous is COVID-19?

Complicated objective factors such as the long-term existence of source of infection, difficulty in completely blocking the transmission route and a large susceptible population suggested that the COVID-19 pandemic might stay with us for long term. Therefore, we should be ready for a tough and long-term battle against the COVID-19 epidemic.


there is SARS-CoV-2 RNA in various clinical specimens, suggesting other transmission routes for this virus besides respiratory secretions

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

Thus, our goal is to test the most active antivirals identified in adequate animal models infected with SARS-CoV-2, to add more information about possible in vivo efficacy. In turn, successful antivirals could be tested in clinical trials as treatments for infected patients, but also as pre-exposure prophylaxis to avoid novel infections until an effective and safe vaccine is developed.


there is SARS-CoV-2 RNA in various clinical specimens, suggesting other transmission routes for this virus besides respiratory secretions

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

The results suggest the effectiveness of Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir as potent drugs against SARS-CoV-2 since they tightly bind to its RdRp. In addition, the results suggest guanosine derivative (IDX-184), Setrobuvir, and YAK as top seeds for antiviral treatments with high potential to fight the SARS-CoV-2 strain specifically.


there is SARS-CoV-2 RNA in various clinical specimens, suggesting other transmission routes for this virus besides respiratory secretions

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

When used for prophylaxis or treatment neither the standard human malaria dose (6.5 mg/kg) nor a high dose (50 mg/kg) of HCQ had any beneficial effect on clinical disease or SARS-CoV-2 kinetics (replication/shedding) in the Syrian hamster disease model. Similarly, HCQ prophylaxis/treatment (6.5 mg/kg) did not significantly benefit clinical outcome nor reduce SARS-CoV-2 replication/shedding in the upper and lower respiratory tract in the rhesus macaque disease model. In conclusion, our preclinical animal studies do not support the use of HCQ in prophylaxis/treatment of COVID-19.


there is SARS-CoV-2 RNA in various clinical specimens, suggesting other transmission routes for this virus besides respiratory secretions

Question: are there any drugs that work for SARS-CoV or SARS-CoV-2 in animals?

We show that a high (5106 pfu) and medium (5104 pfu) dose of SARS-CoV-2 induces consistent upper respiratory tract (URT) viral RNA shedding in both groups of six challenged animals, whilst a low dose (5102 pfu) resulted in only one of six displaying signs of URT viral RNA replication.


Humans first get a coronavirus from contact with animals. Then, it can spread from human to human.

Question: Which are the first symptoms of the coronavirus disease?

The case demonstrate that gastrointestinal symptoms ware not rare in NCIP, and diarrhea could be the initial symptom.


Humans first get a coronavirus from contact with animals. Then, it can spread from human to human.

Question: Which are the first symptoms of the coronavirus disease?

We present a case of coronavirus disease 2019 (COVID-19) with an initial medical presentation of keratoconjunctivitis, the first such reported case in North America. The patient's primary symptom was a red eye with watery discharge, though she did have mild respiratory symptoms, without fever.


Humans first get a coronavirus from contact with animals. Then, it can spread from human to human.

Question: Which are the first symptoms of the coronavirus disease?

The initial symptoms of most patients include fever, cough, and fatigue.


Humans first get a coronavirus from contact with animals. Then, it can spread from human to human.

Question: Which are the first symptoms of the coronavirus disease?

This paper reports the diagnosis and treatment of one COVIN-19 patient with conjunctivitis as the first symptom and one COVIN-19 patient with conjunctivitis.


Question: what is the origin of COVID-19

The results obtained from various AI-enabled experiments using clustering algorithms demonstrate that all examined COVID-19 virus genomes belong to a cluster that also contains bat and pangolin coronavirus genomes.


Question: what is the origin of COVID-19

Zhou et al (1) mentioned that 'Direct contact with intermediate host animals or consumption of wild animals was suspected to be the main route of SARSCoV2 transmission.


Question: what is the origin of COVID-19

The COVID19, which appeared to originate in China in December 2019, has spread worldwide pandemically.


Question: what is the origin of COVID-19

While this novel coronavirus disease (covid-19) frequently induces mild diseases, it has also generated severe diseases among certain populations, including older-aged individuals with underlying diseases, such as cardiovascular disease and diabetes.


Alcohol (beer, wine, distilled spirits or herbal alcohol) stimulates immunity and resistance to the virus

Question: Can drinking alcohol help in preventing COVID-19?

While it remains much too early to determine precisely how alcohol use might affect risk for or progression of COVID19, any efforts to connect the dots from past alcohol research would suggest it wise for nondrinkers and lowrisk drinkers to maintain that status during this public health crisis.


Alcohol (beer, wine, distilled spirits or herbal alcohol) stimulates immunity and resistance to the virus

Question: Can drinking alcohol help in preventing COVID-19?

Is drinking a healthy way of coping? No.


Coronavirus damages not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract

Question: are heart complications likely in patients with COVID-19?

Cardiovascular complications were mainly observed in the confirmed COVID-19+group, consisting of heart failure (9%), palpitations/arrhythmias (3%), stroke/TIA (3%) and pulmonary hypertension (3%). Cardiovascular symptoms such as chest pain (1%), myocardial injury (1%) and pericardial effusion (1%) were also recorded.


Coronavirus damages not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract

Question: are heart complications likely in patients with COVID-19?

consistent reports of cardiac injury and de novo cardiac complications, including possible myocarditis, arrhythmia, and heart failure in patients without prior cardiovascular disease or significant risk factors, are emerging


Coronavirus damages not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract

Question: are heart complications likely in patients with COVID-19?

the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. Patients with heart failure or chronic kidney disease might show an excess risk


Coronavirus damages not only the lungs, but the kidneys, liver, heart, brain and nervous system, skin and gastrointestinal tract

Question: are heart complications likely in patients with COVID-19?

Myocardial injury is significantly associated with fatal outcome of COVID-19, while the prognosis of patients with underlying CVD but without myocardial injury is relatively favorable. Myocardial injury is associated with cardiac dysfunction and arrhythmias. Inflammation may be a potential mechanism for myocardial injury.


healthy blood levels of vitamin D may give patients with COVID-19 a survival advantage by helping them avoid cytokine storm, when the immune system overreacts and attacks your body's own cells and tissues.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L).


healthy blood levels of vitamin D may give patients with COVID-19 a survival advantage by helping them avoid cytokine storm, when the immune system overreacts and attacks your body's own cells and tissues.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

The severity of coronavirus 2019 infection (COVID-19) is determined by the presence of pneumonia, severe acute respiratory distress syndrome (SARS-CoV-2), myocarditis, microvascular thrombosis and/or cytokine storms, all of which involve underlying inflammation.


healthy blood levels of vitamin D may give patients with COVID-19 a survival advantage by helping them avoid cytokine storm, when the immune system overreacts and attacks your body's own cells and tissues.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

Vitamin D deficiency that is not sufficiently treated is associated with COVID-19 risk.


healthy blood levels of vitamin D may give patients with COVID-19 a survival advantage by helping them avoid cytokine storm, when the immune system overreacts and attacks your body's own cells and tissues.

Question: Does Vitamin D impact COVID-19 prevention and treatment?

testing positive for COVID-19 was associated with increasing age(RR(age<50)=1.05,p<0.021;RR(age[]50)=1.02,p<0.064)), non-white race(RR=2.54,p<0.01) and being likely vitamin D deficient (deficient/treatment-not-increased:RR=1.77,p<0.02) as compared to likely vitamin D sufficient(not-deficient/treatment-not-decreased), with predicted COVID-19 rates in the vitamin D deficient group of 21.6%(95%CI[14.0%-29.2%] ) versus 12.2%(95%CI[8.9%-15.4%]) in the vitamin D sufficient group.


Face masks might reduce coronavirus spread

Question: Can face masks protect me from the coronavirus disease?

We find that the critical mask adherence is 5 per 100 when 80% wear face masks.


Face masks might reduce coronavirus spread

Question: Can face masks protect me from the coronavirus disease?

It would therefore be reasonable to suggest that consistent widespread use of face masks in the community could prevent further spread of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2).


Face masks might reduce coronavirus spread

Question: Can face masks protect me from the coronavirus disease?

In this study, we demonstrated, using avian coronavirus of infectious bronchitis virus to mimic SARSCoV2, that medical masks and N95 masks remained their blocking efficacy after being steamed on boiling water even for 2 hours.


Face masks might reduce coronavirus spread

Question: Can face masks protect me from the coronavirus disease?

We also demonstrated that three brands of medical masks blocked over 99% viruses in aerosols. The avian coronavirus was completely inactivated after being steamed for 5 minutes.


There is no research showing that using or consuming any natural or herbal products, including essential oils, eucalyptus oil or witch hazel, will prevent infection with the 2019 novel coronavirus.

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain that was discovered in 2019 and has not been previously identified in humans.


There is no research showing that using or consuming any natural or herbal products, including essential oils, eucalyptus oil or witch hazel, will prevent infection with the 2019 novel coronavirus.

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

Nature provides a huge reservoir of anti-infectious compounds, from which we can deduce innovative ideas, therapies, and products.


There is no research showing that using or consuming any natural or herbal products, including essential oils, eucalyptus oil or witch hazel, will prevent infection with the 2019 novel coronavirus.

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

Foods and herbs could be used as dietary or complementary therapy to prevent infection and strengthen immunity, as antiviral agents for masks, as disinfectants to curb aerosol transmission, or as sanitizing agents to disinfect surfaces. However, these hypotheses need to be experimentally verified for SARS-CoV-2 and COVID-19 patients.


There is no research showing that using or consuming any natural or herbal products, including essential oils, eucalyptus oil or witch hazel, will prevent infection with the 2019 novel coronavirus.

Question: Are there natural remedies that will prevent me from getting infected with COVID-19?

The objective of this study is to determine if the components of natural origin have an anti-viral effect and which can prevent humans from infection by this coronavirus using the most reliable method is molecular docking, which used to find the interaction between studied molecules and the protein, in our case we based on the inhibitor of Coronavirus (nCoV-2019) main protease.


Fever-reducing medicine such as ibuprofen could worsen COVID-19

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

It was recently suggested that ibuprofen might increase the risk for severe and fatal coronavirus disease 2019 (COVID-19) and should therefore be avoided in this patient population.


Fever-reducing medicine such as ibuprofen could worsen COVID-19

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

the safety of ibuprofen in COVID-19 patients has been questioned due to anecdotal reports of worsening symptoms in previously healthy young adults.


Fever-reducing medicine such as ibuprofen could worsen COVID-19

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

It was recently suggested that Ibuprofen might increase the risk for severe and fatal COVID-19 disease and should therefore be avoided in this patient population.


Fever-reducing medicine such as ibuprofen could worsen COVID-19

Question: Can taking medication to lower fever, such as paracetamol (tylenol) and ibuprofen (advil) worsen COVID-19?

When compared to exclusive paracetamol users, no differences were observed in mortality rates or the need for respiratory support among patients using ibuprofen.


In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal

Question: what is the origin of COVID-19

Zhou et al (1) mentioned that 'Direct contact with intermediate host animals or consumption of wild animals was suspected to be the main route of SARSCoV2 transmission.


In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal

Question: what is the origin of COVID-19

However, the source(s) and transmission routine(s) of SARSCoV2 remain elusive' (1).


In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal

Question: what is the origin of COVID-19

The COVID19, which appeared to originate in China in December 2019, has spread worldwide pandemically.


In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal

Question: what is the origin of COVID-19

The results obtained from various AI-enabled experiments using clustering algorithms demonstrate that all examined COVID-19 virus genomes belong to a cluster that also contains bat and pangolin coronavirus genomes.


The question at hand is whether such seasonal clues might apply to the brand-new coronavirus and the disease it causes (COVID-19)

Question: how does the coronavirus respond to changes in the weather

Correcting for that distributed delay and offering conservative estimates, we find a negative relationship between temperatures above 25 degrees Celsius and estimated reproduction number ([R]), with each degree Celsius associated with a 3.1% (95% CI, 1.5% to 4.8%) reduction in [R]. Higher levels of relative humidity strengthen the negative effect of temperature above 25 degrees.


The question at hand is whether such seasonal clues might apply to the brand-new coronavirus and the disease it causes (COVID-19)

Question: how does the coronavirus respond to changes in the weather

Being a novel pandemic coronavirus version, it might be ongoing during summer conditions associated with higher air temperatures, low relative humidity and precipitation levels.


The question at hand is whether such seasonal clues might apply to the brand-new coronavirus and the disease it causes (COVID-19)

Question: how does the coronavirus respond to changes in the weather

the temperature changes retarded the growth rate and found that -6.28{degrees}C and +14.51{degrees}C temperature is the favorable range for COVID-19 growth


The question at hand is whether such seasonal clues might apply to the brand-new coronavirus and the disease it causes (COVID-19)

Question: how does the coronavirus respond to changes in the weather

Each 1 C rise of temperature was associated with a 4.8951% (t = 2.29, p = 0.0226) decrease in the number of daily cumulative confirmed cases of COVID-19


Surgical masks don't offer any protection for the wearer against the new coronavirus

Question: Does a surgical mask help avoid COVID-19?

However, there is a lack of experimental evidence supporting surgical mask usage for prevention of COVID-19.


Surgical masks don't offer any protection for the wearer against the new coronavirus

Question: Does a surgical mask help avoid COVID-19?

Respirators such as filtering face piece (FFP) 2 masks were designed to protect HCWs, while surgical masks were originally intended to protect patients (e.g., during surgery).


Surgical masks don't offer any protection for the wearer against the new coronavirus

Question: Does a surgical mask help avoid COVID-19?

Surgical mask partition for challenged index or nave hamsters significantly reduced transmission to 25% (6/24, P=0.018).


Surgical masks don't offer any protection for the wearer against the new coronavirus

Question: Does a surgical mask help avoid COVID-19?

Such transmission could be reduced by surgical mask usage, especially when masks were worn by infected individuals.


The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered.

Question: what is the origin of COVID-19

While this novel coronavirus disease (covid-19) frequently induces mild diseases, it has also generated severe diseases among certain populations, including older-aged individuals with underlying diseases, such as cardiovascular disease and diabetes.


The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered.

Question: what is the origin of COVID-19

Zhou et al (1) mentioned that 'Direct contact with intermediate host animals or consumption of wild animals was suspected to be the main route of SARSCoV2 transmission.


The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered.

Question: what is the origin of COVID-19

This paper investigates the COVID-19 virus origin by using artificial intelligence (AI) and raw genomic sequences of the virus.


The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered.

Question: what is the origin of COVID-19

The COVID19, which appeared to originate in China in December 2019, has spread worldwide pandemically.


No, 5G does not cause COVID-19 or create the coronavirus

Question: Can 5G technology cause COVID-19?

5G-based robot-assisted remote ultrasound system is feasible, and effectively obtains ultrasound characteristics for cardiopulmonary assessment of COVID-19 patients.


No, 5G does not cause COVID-19 or create the coronavirus

Question: Can 5G technology cause COVID-19?

Amongst them, a popular theory has linked 5G to the spread of COVID-19, leading to misinformation and the burning of 5G towers in the United Kingdom.


No, 5G does not cause COVID-19 or create the coronavirus

Question: Can 5G technology cause COVID-19?

these patterns are not specific to 5G conspiratorial beliefs


No, 5G does not cause COVID-19 or create the coronavirus

Question: Can 5G technology cause COVID-19?

The aim of this study is to develop an understanding of the drivers of the 5G COVID-19 conspiracy theory and strategies to deal with such misinformation.


A few pets - including cats and dogs - also have been infected with the virus that causes COVID-19. This happened mostly after the animals were in close contact with people infected with the COVID-19 virus.

Question: Can animals spread COVID-19?

On April 22, CDC and the U.S. Department of Agriculture (USDA) reported cases of two domestic cats with confirmed infection with SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19).


A few pets - including cats and dogs - also have been infected with the virus that causes COVID-19. This happened mostly after the animals were in close contact with people infected with the COVID-19 virus.

Question: Can animals spread COVID-19?

It is now accepted that the wild fauna, probably bats, constitute the initial reservoir of the virus, but little is known about the role pets can play in the spread of the disease in human communities, knowing the ability of SARS-CoV-2 to infect some domestic animals.


A few pets - including cats and dogs - also have been infected with the virus that causes COVID-19. This happened mostly after the animals were in close contact with people infected with the COVID-19 virus.

Question: Can animals spread COVID-19?

There is currently no indication that feline- or canine-to-human transmission can occur, though there is rising evidence of the reverse.


A few pets - including cats and dogs - also have been infected with the virus that causes COVID-19. This happened mostly after the animals were in close contact with people infected with the COVID-19 virus.

Question: Can animals spread COVID-19?

These are the first reported companion animals (including pets and service animals) with SARS-CoV-2 infection in the United States, and among the first findings of SARS-CoV-2 symptomatic companion animals reported worldwide.


At this point, we don't know enough about coronavirus to understand how it's going to behave over time when the weather warms up.

Question: how does the coronavirus respond to changes in the weather

The current study focuses on the relationship between environmental parameters and the growth rate of COVID-19. The statistical analysis suggests that the temperature changes retarded the growth rate and found that -6.28C and +14.51C temperature is the favorable range for COVID-19 growth.


At this point, we don't know enough about coronavirus to understand how it's going to behave over time when the weather warms up.

Question: how does the coronavirus respond to changes in the weather

We show that the delay between exposure and detection of infection complicates the estimation of weather impact on COVID-19 transmission, potentially explaining significant variability in results to-date


At this point, we don't know enough about coronavirus to understand how it's going to behave over time when the weather warms up.

Question: how does the coronavirus respond to changes in the weather

Temperature is the most influential parameter that reduces the growth at the rate of 13-16 cases/day with a 1{degrees}C rise in temperature


At this point, we don't know enough about coronavirus to understand how it's going to behave over time when the weather warms up.

Question: how does the coronavirus respond to changes in the weather

the temperature changes retarded the growth rate and found that -6.28{degrees}C and +14.51{degrees}C temperature is the favorable range for COVID-19 growth


The truth is that the flu is a lot less deadly than COVID

Question: How dangerous is COVID-19?

Covid-19 is a disease caused by a new coronavirus presenting a variability of flu-like symptoms including fever, cough, myalgia and fatigue; in severe cases, patients develop pneumonia, acute respiratory distress syndrome, sepsis and septic shock, that can result in their death.


Question: Can smoking cannabis (weed) help in preventing COVID-19?

Male, older than 65, and smoking were risk factors for disease progression in patients with COVID-19 (male: OR=1.76, 95% CI (1.41, 2.18), P < 0.00001;


Question: Can smoking cannabis (weed) help in preventing COVID-19?

Male, aged over 65, smoking patients might face a greater risk of developing into the critical or mortal condition and the comorbidities such as hypertension, diabetes, cardiovascular disease, and respiratory diseases could also greatly affect the prognosis of the COVID-19.


Question: Can smoking cannabis (weed) help in preventing COVID-19?

An epidemic of Coronavirus Disease 2019 (COVID-19) began in December 2019 and triggered a Public Health Emergency of International Concern (PHEIC). We aimed to find risk factors for the progression of COVID-19 to help reducing the risk of critical illness and death for clinical help.


Question: Can smoking cannabis (weed) help in preventing COVID-19?

Cannabis thus joins tobacco as a SARS2-CoV-2 risk factor.


ATS and dogs can transmit coronavirus to humans via their fur

Question: Can animals spread COVID-19?

There is currently no indication that feline- or canine-to-human transmission can occur, though there is rising evidence of the reverse.


ATS and dogs can transmit coronavirus to humans via their fur

Question: Can animals spread COVID-19?

Notification of presumptive positive animal test results triggered a One Health* investigation by state and federal partners, who determined that no further transmission events to other animals or persons had occurred.


ATS and dogs can transmit coronavirus to humans via their fur

Question: Can animals spread COVID-19?

Although there is currently no evidence that animals play a substantial role in spreading COVID-19,


ATS and dogs can transmit coronavirus to humans via their fur

Question: Can animals spread COVID-19?

Coronavirus disease-19 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is now a pandemic threat. This virus is supposed to be spread by human to human transmission.


In many of the sickest patients with COVID-19, it seems the worst damage may be driven by a deranged immune response to the infection, called a cytokine storm, rather than the virus itself.

Question: will SARS-CoV2 infected people develop immunity?

According to this hypothesis vaccine formulations (tetanus, diphtheria, Bordetella pertussis) could be re-administrate after the first contact with Covid-19, better before the development of respiratory severe illness and of course before full-blown ARDS (Acute Respiratory Distress Syndrome). The CD4+ memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting lung crash until virus specific immunity develops and making it faster and prolonged.


In many of the sickest patients with COVID-19, it seems the worst damage may be driven by a deranged immune response to the infection, called a cytokine storm, rather than the virus itself.

Question: will SARS-CoV2 infected people develop immunity?

The CD4 + memory exploiting could help immune system to recall immunity of already know antigens against coronaviruses, avoiding or limiting "lung crash" until virus specific immunity develops and making it faster and prolonged. Finally, this administration could be helpful not only in already infected patients, but also before infection. In fact, people could have an immune system more ready when the contact with the Covid-19 will occur.


In many of the sickest patients with COVID-19, it seems the worst damage may be driven by a deranged immune response to the infection, called a cytokine storm, rather than the virus itself.

Question: will SARS-CoV2 infected people develop immunity?

In this study, we collected blood from COVID-19 patients who have recently become virus-free and therefore were discharged, and analyzed their SARS-CoV-2-specific antibody and T cell responses. We observed SARS-CoV-2-specific humoral and cellular immunity in the patients. Both were detected in newly discharged patients, suggesting both participate in immune-mediated protection to viral infection.


In many of the sickest patients with COVID-19, it seems the worst damage may be driven by a deranged immune response to the infection, called a cytokine storm, rather than the virus itself.

Question: will SARS-CoV2 infected people develop immunity?

Thus both qualitative and quantitative features of B and T cell immunity to spike constitute informative biomarkers of the protective potential of novel SARS-CoV-2 vaccines.


COVID-19 cannot be transmitted in hotter, more humid climates

Question: how does the coronavirus respond to changes in the weather

Correcting for that distributed delay and offering conservative estimates, we find a negative relationship between temperatures above 25 degrees Celsius and estimated reproduction number ([R]), with each degree Celsius associated with a 3.1% (95% CI, 1.5% to 4.8%) reduction in [R]. Higher levels of relative humidity strengthen the negative effect of temperature above 25 degrees.


COVID-19 cannot be transmitted in hotter, more humid climates

Question: how does the coronavirus respond to changes in the weather

Each 1 C rise of temperature was associated with a 4.8951% (t = 2.29, p = 0.0226) decrease in the number of daily cumulative confirmed cases of COVID-19


COVID-19 cannot be transmitted in hotter, more humid climates

Question: how does the coronavirus respond to changes in the weather

Preliminary observations from our team and others suggest that temperature and climatological factors could influence the spread of this novel coronavirus


COVID-19 cannot be transmitted in hotter, more humid climates

Question: how does the coronavirus respond to changes in the weather

COVID-19, due to its regular flu-like symptoms, is also expected to show similar seasonality and subside as the global temperatures rise in the northern hemisphere with the onset of spring


Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs).

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

current evidence did not confirm the concern that ACEI/ARB exposure is harmful in patientswith COVID-19 infection. This study supports the current guidelines that discourage discontinuation of ACEIs or ARBs in COVID-19 patients and the setting of the COVID-19 pandemic


Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs).

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

Patients who take ACEIs and ARBS may be at increased risk of severe disease outcomes due to SARS-CoV-2 infections.


Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs).

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

among patients who were diagnosed with COVID-19, ACEI/ARB use was not associated with increased risk of hospital admission.


Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs).

Question: are patients taking Angiotensin-converting enzyme inhibitors (ACE) inhibitors at increased risk for COVID-19?

Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers are not associated with severe COVID-19 infection in a multi-site UK acute hospital trust


Dexamethasone can not improve COVID-19 survival

Question: Is dexamethasone effective for treating COVID-19?

We designed a trial to evaluate the effectiveness of early intravenous dexamethasone administration on the number of days alive and free of mechanical ventilation within 28 days after randomization in adult patients with moderate or severe ARDS due to confirmed or probable COVID-19.


Dexamethasone can not improve COVID-19 survival

Question: Is dexamethasone effective for treating COVID-19?

Corticosteroids could be useful in patients with an inflammatory profile, considering that acute respiratory distress syndrome may be the consequence of cytokine storm syndrome. LEARNING POINTS: One of the main pathophysiological hypotheses for severe COVID-19 pneumonia is inappropriate immunological hyperactivation. Corticosteroid therapy may be useful in these patients.


Dexamethasone can not improve COVID-19 survival

Question: Is dexamethasone effective for treating COVID-19?

Hence, dexamethasone may be useful for the short-term in severe, intubated, COVID-19 patients, but could be outright dangerous during recovery since the virus will not only persist, but the body will be prevented from generating protective antibodies.


Dexamethasone can not improve COVID-19 survival

Question: Is dexamethasone effective for treating COVID-19?

Many drugs have shown promise for treatment of COVID-19.


wearing a mask is effective in preventing COVID-19

Question: what are the best masks for preventing infection by Covid-19?

Respirators such as filtering face piece (FFP) 2 masks were designed to protect HCWs, while surgical masks were originally intended to protect patients (e.g., during surgery). Nevertheless, high quality standard surgical masks (type II/IIR according to European Norm EN 14683) appear to be as effective as FFP2 masks in preventing droplet-associated viral infections of HCWs as reported from influenza or SARS.


wearing a mask is effective in preventing COVID-19

Question: what are the best masks for preventing infection by Covid-19?

Since droplet transmission is the main route of transmission, wearing a mask serves as a crucial preventive measure.


wearing a mask is effective in preventing COVID-19

Question: what are the best masks for preventing infection by Covid-19?

Ma's research shows N95 masks, medical masks, even homemade masks could block at least 90% of the virus in aerosols


wearing a mask is effective in preventing COVID-19

Question: what are the best masks for preventing infection by Covid-19?

Most hospitals have implemented universal masking for their healthcare workers, and the Center for Disease Control currently advises even the general public to wear cloth masks when outdoors. The pertinent need for masks arises from plausible dissemination of the SARS-CoV-2 through close contacts, as well as the possibility of virus transmission from asymptomatic, pre-symptomatic, and mildly symptomatic individuals.


Obesity Ups Severe COVID-19 Risk in Young Patients

Question: are heart complications likely in patients with COVID-19?

The cardiovascular system is also affected, with complications including myocardial injury, myocarditis, acute myocardial infarction, heart failure, dysrhythmias, and venous thromboembolic events. Current therapies for COVID-19 may interact with cardiovascular medications.


Obesity Ups Severe COVID-19 Risk in Young Patients

Question: are heart complications likely in patients with COVID-19?

the greater susceptibility of individuals with underlying cardiovascular conditions to develop more severe Covid-19 with higher mortality rate is likely to be confounded, in part, by age and the type of co-morbidities. Patients with heart failure or chronic kidney disease might show an excess risk


Obesity Ups Severe COVID-19 Risk in Young Patients

Question: are heart complications likely in patients with COVID-19?

The clinical evidence in our study suggested that myocardial injury is more likely related to systemic consequences rather than direct damage by the 2019 novel coronavirus. The elevation in cardiac markers was probably due to secondary and systemic consequences and can be considered as the warning sign for recent adverse clinical outcomes of the patients


Obesity Ups Severe COVID-19 Risk in Young Patients

Question: are heart complications likely in patients with COVID-19?

Cardiovascular complications were mainly observed in the confirmed COVID-19+group, consisting of heart failure (9%), palpitations/arrhythmias (3%), stroke/TIA (3%) and pulmonary hypertension (3%). Cardiovascular symptoms such as chest pain (1%), myocardial injury (1%) and pericardial effusion (1%) were also recorded.


In the absence of a vaccine to protect people from Covid-19, the disease caused by the coronavirus SARS-CoV-2, minimising the spread of the virus is of utmost importance.

Question: has social distancing had an impact on slowing the spread of COVID-19?

the centralized social distancing is necessary to minimize the pandemic spreading.