This paper addresses the problem of learning a task from demonstration. We adopt the framework of inverse reinforcement learning, where tasks are represented in the form of a reward function. Our contribution is a novel active learning algorithm that enables the learning agent to query the expert for more informative demonstrations, thus leading to more sample-efficient learning. For this novel algorithm (Generalized Binary Search for Inverse Reinforcement Learning, or GBS-IRL), we provide a theoretical bound on sample complexity and illustrate its applicability on several different tasks. To our knowledge, GBS-IRL is the first active IRL algorithm with provable sample complexity bounds. We also discuss our method in light of other existing methods in the literature and its general applicability in multi-class classification problems. Finally, motivated by recent work on learning from demonstration in robots, we also discuss how different forms of human feedback can be integrated in a transparent manner in our learning framework.
@cite_9: Objective—To evaluate the pharmacokinetics of a novel commercial formulation of ivermectin after administration to goats. Animals—6 healthy adult goats. Procedure—Ivermectin (200 μg kg) was initially administered IV to each goat, and plasma samples were obtained for 36 days. After a washout period of 3 weeks, each goat received a novel commercial formulation of ivermectin (200 μg kg) by SC injection. Plasma samples were then obtained for 42 days. Drug concentrations were quantified by use of high-performance liquid chromatography with fluorescence detection. Results—Pharmacokinetics of ivermectin after IV administration were best described by a 2-compartment open model; values for main compartmental variables included volume of distribution at a steady state (9.94 L kg), clearance (1.54 L kg d), and area under the plasma concentration-time curve (AUC; 143 [ng•d] mL). Values for the noncompartmental variables included mean residence time (7.37 days), AUC (153 [ng•d] mL), and clearance (1.43 L kg d). After ...
In this paper, as already mentioned, we adopt the inverse reinforcement learning (IRL) formalism introduced in the seminal paper by @cite_9 . One appealing aspect of the IRL approach to learning from demonstration is that the learner is not just mimicking'' the observed actions. Instead, the learner infers the purpose behind the observed behavior and sets such purpose as its goal. IRL also enables the learner to accommodate for differences between itself and the demonstrator .