The Rams are 10th in the Championship, nine points adrift of the top six.
Scotland international Bryson said: "This season's not been good enough. The players must take responsibility.
"If we don't make the play-offs this season we have to build for next season and put things right."
Derby face QPR at Pride Park on Friday in their second game under new manager Gary Rowett.
Another match against London opposition follows on Tuesday, when the Rams are away to play-off rivals Fulham.
"I don't think we can have any more slips," Bryson added.
"The gap is too big. In this league, if you go on a run and win three or four in a row then you never know.
"The games coming up are basically must-win for us if we are going to have any chance. You have to believe.
"We still have eight games to get a wee bit of pride in the season because it's not been the best."
Derby County's players must show pride in the last eight games of a season of underachievement even if they fail to reach the play-offs, says midfielder Craig Bryson.