Police Scotland said the drugs were seized in Church Place on Monday.
The men, aged 25 and 28, and the woman, 39, were arrested and charged. They have since appeared at Falkirk Sheriff Court.
Detectives urged anyone with information about the sale and supply of illegal substances to contact them.
Two men and a woman have appeared in court after heroin with an estimated value of about £250,000 was recovered in Falkirk.