Furious 7 has already out-grossed all previous instalments of the 14-year-old franchise and has now made more than $800m (£546m) internationally.
With DreamWorks animation Home berthed at two, new release The Longest Ride could only muster a third place debut.
The rodeo-based romance made $13.5m (£9.2m) between Friday and Sunday.
Starring Clint Eastwood's son Scott, the film is the latest to be adapted from a best-selling novel by Nicholas Sparks.
Further down this week's Top 10, Woman in Gold appears at seven after expanding its release to more than 1,500 locations.
Starring Dame Helen Mirren, this story of an attempt to recover art looted by the Nazis made $5.9m (£4m) in its second weekend in North American cinemas.
According to Screen Daily, Furious 7 has now made more than $39m (£26.6m) in the UK and Ireland, where it was released as Fast & Furious 7.
The latest Fast and the Furious film is still top dog at the US and Canada box office, having taken $60.6m (£41.4m) in its second weekend in cinemas.