What is the fine-grained topic of the following text: The aim of this study was to establish a method to determine the presence of anti-taxane antibodies in body fluids of patients who have previously received paclitaxel, in order to estimate the risk of the occurrence of HSR to other taxane compounds, such as docetaxel. Only return the topic.
Determining the presence of anti-taxane antibodies in patients who have received paclitaxel.