What is the fine-grained topic of the following text: Furthermore, in a case of low-differentiated neuroendocrine cancer it was shown that large tumours with high proliferation can also be treated with this method and that tumour-to-risk organ ratios can improve in later cycles, resulting in a more effective treatment. Only return the topic.
Treatment of low-differentiated neuroendocrine cancer with a method improving tumour-to-risk organ ratios in later cycles