What is the fine-grained topic of the following text: The global phase 3 NAPOLI-1 study demonstrated that ONIVYDE in combination with 5-FU/LV extended overall survival, progression-free survival and increased tumor response rate, without compromising quality of life as compared to 5-FU/LV alone in metastatic pancreatic cancer patients who have progressed after gemcitabine-based therapy. Only return the topic.
The efficacy of ONIVYDE in combination with 5-FU/LV in treating metastatic pancreatic cancer