What is the fine-grained topic of the following text: MHC Multimers such as Dextramers® are used for detection, enumeration and isolation of antigen-specific T cells in fluid cell samples (PBMC, blood) by flow cytometry, and can be applied to tissue sections to visualize antigen-specific T cells in situ.Fields of application are vaccine and immunotherapeutic development, clinical trials, immune monitoring of transplantation patients, patients with HIV and many more. Only return the topic.
The use and applications of MHC Multimers in detecting and isolating antigen-specific T cells.