What is the fine-grained topic of the following text: The aim of this trial is to investigate whether early detection of the risk of cardiovascular diseases (CVD), quantified by either the classical risk score (SCORE) or a coronary artery calcium-score (CT scan), will reduce morbidity and mortality from CVD in a high-risk population. Only return the topic.
Early detection of cardiovascular diseases risk and its impact on morbidity and mortality.