What is the fine-grained topic of the following text: The study, which appears Oct. 24, 2011 in the online journal PLoS ONE, suggests that this early-stage dormancy phenomenon contributes to the failure of artesunate alone, or even combined with other drugs, to eliminate the mosquito-borne disease. Only return the topic.
Early-stage dormancy phenomenon's contribution to the failure of malaria treatment with artesunate and other drugs.