What is the fine-grained topic of the following text: Relative to similar treatments with other Ad serotypes, HAd3 and SAd23 induced altered innate immune responses, illustrated by induction of higher levels of cellular gene transcription in several tissues, and higher plasma levels of cytokines and chemokines. Only return the topic.
Altered innate immune responses induced by HAd3 and SAd23 treatments compared to other Ad serotypes.