What is the fine-grained topic of the following text: A bioinformatics analysis revealed that greater number of putative promoters of immune related genes and also those not directly involved in immunity contain GAS compared to response elements (RE) for Interferon Regulatory Factor (IRF)1, Nuclear factor kappa B (NF kappa B) and Activator Protein (AP)1. Only return the topic.
Bioinformatics analysis of gene promoters and response elements in immune related genes