What is the fine-grained topic of the following text: It is set in 1960s when it was discovered that rebalancing the dopamine levels in the brains of these zombie-like patients using medicines such as L-Dopa could bring them back to life, i.e., 'awaken' them from their stupor. Only return the topic.
Use of L-Dopa medicine to 'awaken' patients with disturbed dopamine levels in the 1960s