What is the fine-grained topic of the following text: In addition, it has been witnessed that people who are treated with sildenafil citrate (Tadalies Soft) had significantly lower blood pressure and heart rate as well as significant improvement in oxygen consumption and carbon dioxide production. Only return the topic.
Effects of Sildenafil Citrate (Tadalies Soft) on blood pressure, heart rate, oxygen consumption, and carbon dioxide production.