What is the fine-grained topic of the following text: Ito A1, Sasaguri Y, Kitada S, Kusaka Y, Kuwano K, Masutomi K, Mizuki E, Akao T, Ohba M.
Bacillus thuringiensis crystal proteins, well known to be toxic to certain insects but not pathogenic to mammals, are used as insecticidal proteins in agriculture and forest management. Only return the topic.
Use of Bacillus thuringiensis crystal proteins in agriculture and forest management for insect control