What is the fine-grained topic of the following text: When cases were strati?ed according to p53 status and Pin1 expression levels,overall survival was found to be signi?cantly decreased in patients with tumorsexpressing high levels of Pin1 and p53 missense mutations, compared to cases with lowPin1 expression and p53 missense mutations, or cases bearing wild-type p53 [ 11 ].In addition, p53 mutation correlates with shorter OS only in cases with high Pin1expression levels. Only return the topic.
The impact of Pin1 expression levels and p53 status on overall survival in cancer patients.