The present study explored presence of meaning in life, search for meaning in life, and their correlation with health anxiety. The Meaning in Life Questionnaire and the Short Health Anxiety Inventory were completed by 753 individuals. Results indicated higher presence of meaning in life was associated with lower health anxiety, while the opposite was observed for search for meaning in life. Results also revealed an interaction between presence of meaning in life and search for meaning in life, where individuals with high search for meaning in life and high presence of meaning in life had lower health anxiety than those with high search for meaning in life and low presence of meaning in life. These findings suggest that presence of meaning in life and search for meaning in life are correlates of health anxiety.