Discontinuous Galerkin (DG) methods allow high-order flow solutions on unstructured or locally refined meshes by increasing the polynomial degree and using curved instead of straight-sided elements. However, one of the currently largest obstacles to applying these methods to aerodynamic configurations of medium to high complexity is the availability of appropriate higher-order curved meshes. In this article, we describe a complete chain of higher-order unstructured grid generation and higherorder DG flow solution applied to a turbulent flow around a three-dimensional high-lift configuration. This includes (i) the generation of an appropriately coarse straight-sided mesh; (ii) the evaluation of additional points on the computer-aided design geometry of the curved-wall boundary for defining a piecewise polynomial boundary representation; (iii) a higher order mesh deformation to translate the curvature from the wall boundary into the interior of the computational domain; and (iv) the description of a DG discretization, which is sufficiently stable to allow a flow computation on the resulting curved mesh. Finally, a fourth-order flow solution of the Reynolds-averaged Navier-Stokes and k-! turbulence model equations is computed on a fourth-order unstructured hybrid mesh around the three-dimensional high-lift simulation of wing-flow noise generation configuration. Copyright (C) 2016 John Wiley & Sons, Ltd.