A turbocharger compressor working in commercial vehicles, especially in some passenger cars, often works together with some pipes with complicated geometry as an air intake system, due to limit of available space in internal combustion engine compartments. These pipes may generate various distortions of physical parameters of the air at the inlet of the compressor and therefore the compressor aerodynamic performance deteriorates. Sometimes, the turbocharging engine fails to work at some operation points. This paper investigates the effects of various swirl distortions induced by different bending-torsional intake ducts on the aerodynamic performance of a turbocharger compressor by both 3D numerical simulations and experimental measurements. It was found that at the outlet of the pipes the different inlet ducts can generate different swirl distortions, twin vortices and bulk-like vortices with different rotating directions. Among them, the bulk-like vortices not only affect seriously the pressure distribution in the impeller domain, but also significantly deteriorate the compressor performance, especially at high flow rate region. And the rotating direction of the bulk-like vortices is also closely associated with the efficiency penalty. Besides the efficiency, the transient flow rate through a single impeller channel, or the asymmetric mass flow crossing the whole impeller, can be influenced by two disturbances. One is from the upstream bending-torsional ducts; other one is from the downstream volute.