Syrian conflict and oppression caused extreme suffering for Syrians. They threatened the existence of Syrian identity and Syria's territorial integrity. They caused more than half of Syria's population to be internally displaced or become refugees. The goal of the current study was to assess the physical and mental health toll of Syrian experience, an intergroup trauma, on Syrians as individuals. A sample of 195 internally displaced and 111 Syrian refugees in the Nederland was administered measures of oppressive Syrian experience (SOE), cumulative stress and trauma, posttraumatic stress disorder ( PTSD), postcumulative stress and trauma disorders (complex PTSD), and existential annihilation anxiety (EAA). Descriptive statistics showed high rates of PTSD, comorbidities, and suicidality. Internally displaced had significantly higher morbidity rates than refugees. Using path analysis, we tested a model where SOE, mediated by other interpersonal traumas, triggered EAA and affected severely their mental and physical health. The model fitted well. We tested the model's structural invariance across genders and the 2 groups. While the model was configurally and metrically (conceptually) invariant across groups, it was not strongly or strictly invariant. We examined the dynamics behind their similarities and differences. We discussed the need to resolve the conflict and develop evidence-based interventions to help relieve their suffering.