In order to investigate the characteristics of the vibration of the windvehicle-bridge (WVB) coupling system during two trains meeting each other, the dynamic response of the WVB system has been analyzed when the two trains meeting on a large span suspension bridge using the self-developed software BANSYS. Particularly, the aerodynamic coefficients of the bridge and the two trains before and after the meeting are determined through wind tunnel tests. It is shown that the wind loads and the responses of the leeward vehicle change abruptly in the meeting process compared with the case with a single train. And the responses of the leeward vehicle increase with the growing of wind speed and vehicle speed, and decrease with the enlarging of the lateral distance between the two trains. The processes of two trains meeting each other are the control factors for the WVB coupling system.