The multifunctional intelligent information sensor system is developed by using of nanostructured multilayer thickfilm structures based on spinel-type NiMn2O4-CuMn2O4MnCo2O4 manganites and magnesium aluminate MgO-Al2O3. The technological features of nanostructured sensor preparation are represented. The diagram of this system is proposed. This system with microprocessor signal processing is shown to be successfully applied for integrated temperature/humidity environment monitoring and control.