This paper proposes a 0.5V smart image sensor with multi-operation modes of edge extraction, centroid tracking, and high-dynamic-range imaging output. The 0.5V operated pulse-width-modulation (PWM) sensor [1] is applied to achieve a high dynamic range (HDR) response and reduce the fixed pattern noise (FPN). The array-level analog signal processing (ASP) is implemented by local inter-pixel feedback and the event-driven (ED) hand-shaking readout. A prototype chip of smart image sensor with 64x64 CIS array was fabricated in 0.18um CMOS technology. The prototype has been verified to demonstrate the features of real-time edge extraction, object tracking, and high-dynamic range imaging successfully. The measurement results show a power dissipation of 34.4uW in edge extraction mode, a frame rate of 14.28kfps and a tracking error of 0.36 pixels in centroid tracking mode, and a high dynamic range (DR) of 105dB in imaging mode.