This paper presents a fully coupled multiphysics model developed for numerical simulation of the elastohydrodynamically lubricated contact between a cam and roller, typically found in cam mechanisms controlling fuel injection in an internal combustion engine. Special attention was focused on enabling systematic analyses of effects associated with, roller crowning and edge geometries, lubricant rheology as well as typical cam mechanism operating conditions. The interaction between the cam and roller follower result in high generated pressure and narrow film thickness that increase the risk of wear and fatigue. Furthermore, this article highlights the variation of pressure and film thickness under tilting conditions. The model was also validated against some particular model problems, found in the literature. (C) 2016 The Authors. Published by Elsevier Ltd.