Previous research has revealed that mode of delivery is the most important attribute for consumers in selecting a probiotic product. Therefore, determining the predictors of consumers' preferred mode of delivery of probiotics is of particular importance for public health policy makers, marketers and developers of probiotic products. Functional foods, food supplements, and pharmaceuticals are the considered modes of delivery in this study. To assess the most important determinants, a survey was performed in Belgium with adult volunteers (n = 503) of whom 18 percent were Inflammatory Bowel Disease (IBD) patients. The results indicate that functional foods are the most preferred mode of delivery of probiotics. Furthermore, significant odds ratios were obtained for digestive health, knowledge of probiotics, familiarity with functional foods and familiarity with food supplements.