Today, there is an increasing need for researchers to demonstrate the practical value their research can generate for society. Over the past decade, experts in transdisciplinary research have developed numerous principles, methods, and tools for making research more societally relevant. If researchers are unfamiliar with transdisciplinary research, they may miss opportunities to adapt these principles and tools to their research projects. We are developing a 10-step approach for joint use by transdisciplinarity experts and researchers about how to best align their research projects with the requirements of transdisciplinarity. We have successfully applied this approach in numerous workshops, summer schools, and seminars at ETH Zurich and beyond. Ten questions guide discussions between transdisciplinarity experts and researchers around research issues, identify and review the societal problems addressed, identify relevant actors and disciplines, and clarify the purpose and form of the inter action with them. The feedback we have obtained clearly indicates that the 10-step approach is a very useful tool: It provides a systematic procedure for thinking through ways to better link research to societal problem solving.