The study of child abuse effects in conjunction with witnessing domestic violence has shown some influence of this dual exposure on the development of behavior problems in children. Thus, this study goal was to analyze the likely influence of dual exposure on adolescent drug use and antisocial behavior. The sample comprised 247 adolescents from juvenile offenders and foster care centers in the autonomous community of Galicia (Spain). Results showed that adolescents who have witnessed family violence had higher rates of aggressive and rule-breaking behaviors, theft and substance abuse, as well as more frequent use of alcohol, cannabis and cocaine, compared to: a) youths without history of family violence, b) adolescents maltreated in childhood, and c) those with dual victimization.