Some of the activities of the Project Center for Nanotechnology and Advanced Engineering (PC-NAE) in manufacturing engineering are reported, focusing onto some recent trends and developments in advanced manufacturing of advanced materials, in the important engineering topics from industrial, research and academic point of view: nanotechnology/nanostructured materials, ultraprecision engineering, net shape manufacturing, mainly powder processing under shock loading and their applications in various fields of science and engineering e.g. machine tool industry, biomedicines, energy conservation and transport, namely automotive and aircraft industry, etc.