Since the birth of clickers at Pennsylvania State University, there have been numerous arguments on its effectiveness. This study, aiming to review use of clickers in education, examined literature over around a decade on use of clickers, involving benefits and defects of use of clickers, peer discussion, use of clickers in learning, teaching and problem solving, the effectiveness of use of clickers among non-students. Besides, relationships between lecturing and learning aided with clickers, and current developments in use of clickers were also reviewed and discussed. It was concluded that clickers, as one form of modern technology, had gained growing popularity due to their advantages, such as peer discussion, anonymity and instant feedback although disputes still remained. More studies on clickers and other new technologies were still needed to further push forward levels of education. Cross-disciplinary cooperation between computers, education and psychology may be needed to design more advanced educational technologies.