Full-spectrum dependent types promise to enable the development of correct-by-construction software. However, even certified software needs to interact with simply-typed or untyped programs, be it to perform system calls, or to use legacy libraries. Trading static guarantees for runtime checks, the dependent interoperability framework provides a mechanism by which simplytyped values can safely be coerced to dependent types and, conversely, dependently-typed programs can defensively be exported to a simply-typed application. In this paper, we give a semantic account of dependent interoperability. Our presentation relies on and is guided by a pervading notion of type equivalence, whose importance has been emphasized in recent work on homotopy type theory. Specifically, we develop the notion of partial type equivalences as a key foundation for dependent interoperability. Our framework is developed in Coq; it is thus constructive and verified in the strictest sense of the terms. Using our library, users can specify domain-specific partial equivalences between data structures. Our library then takes care of the (sometimes, heavy) lifting that leads to interoperable programs. It thus becomes possible, as we shall illustrate, to internalize and hand-tune the extraction of dependently-typed programs to interoperable OCaml programs within Coq itself.