In this paper, a novel versatile active building block the differential-input buffered and transconductance amplifier (DBTA) is proposed. The application of the newly defined active function block is shown on the design of voltage-mode (VM), multi-input and single-output (MISO)-type multifunction biquad, employing single DBTA and five passive elements. Proposed VM filter structure can realize four filter functions i.e., low-(LP), band-(BP), high-pass (HP) and band-stop (BS) without changing the circuit topology and enables independent control of the quality factor Q using single passive element. Theoretical results are verified by PSPICE simulations using a BJT realization of DBTA.