The Adriatic-Ionian macro region is one of the four Mediterranean sub-regions, recorded approximately 5.2 million of cruise passengers and 17 million ferry passengers in 2013. The study performed within the WP4 of EA SEA-WAY project covered twenty ports in six countries of the Adriatic-Ionian region and their hinterland connections assessment. The primary objective of each database is to enable a comprehensive view of data making it easier to focus on analysis. Database should have functionalities such as systematization, timelines collection and data entry into one place by using user friendly interface. For developing big databases, such as database for EA SEA-WAY project, there is a need for making a model to provide the integrity and interconnectedness data. Relational databases have dominated the software industry for a long and ERD (Entity-Relationship Diagram) and it is used to visually represents the relationship between database entities. Also, it is very important to decide which DBMS (Database Management System) to use in creating database. In this paper is presented a solution for EA SEA-WAY project database as a useful assessment tool for the ports and other stakeholders in the Adriatic-Ionian macro region.