Hereditary angioedema (HAE) is a rare debilitating autosomal dominant disorder caused by mutations in the C1-inhibitor gene that results in increased bradykinin levels. It is usually misdiagnosed as histaminergic angioedema which occurs more commonly and is associated with urticaria. We report this disorder in a young male who presented to us with dyspnoea, recurrent bouts of painful swelling involving various parts of body and abdominal cramps without any signs of urticaria. The patient was diagnosed as HAE Type I based on history, poor response to treatment of histaminergic angioedema and low C4, C1-INH antigenic levels.