The Textile industry is the largest manufacturing industry at Pakistan that has good reputation in global supply chains. Organizations want to achieve excellence by optimally utilizing their human capital. Socio-technical complexity of working systems along with high level of expectations, workplace stress management has become an area of deep concern where textile sector is no exception. It is highly important to address stress related issues so that organizations can capitalize benefits related to their human resource by ensuring their well-being at all levels. People involved in management, are expected to be vulnerable to stress because of their critical role in organizations. The objective of this study is to identify causes of workplace stress among managers of textile industry. In this cross-sectional study, data through a questionnaire has been collected from 125 managers from different areas of textile sector like spinning, weaving and apparel manufacturing. Exploratory factor analysis has been carried out where factors like physical agents at work, training and development, support at work, family/work interface, work environment and role have been found to be the major causes of workplace stress.