Objective: To review the current literature for evidence regarding the feasibility and efficacy of smartphone-based cognitive-behavioral intervention mobile applications, compare such to the number of applications on the commercial marketplaces, and explore potential steps forward for research in the field. Methods: A literature search was conducted for papers published before February 2015 featuring quantitative results on clinical outcomes regarding the use of a smartphone for cognitive behavioral therapy, dialectical behavioral therapy, behavioral activation, and acceptance and commitment therapy. A search for the number of related applications available to consumers on the Apple and Google Play commercial marketplaces was also conducted. Results: Nine studies, described in 11 articles, were identified that featured the use of smartphones in cognitive-behavioral interventions. The majority of studies presented pilot results suggesting the potential feasibility/efficacy of such apps. Four hundred and forty-seven related applications were found to be available on, the commercial marketplaces. Conclusions: The research base for smartphone-based cognitive-behavioral intervention mobile applications is preliminary at this point although results are encouraging. There is a discrepancy between the published literature and commercial applications available to consumers. We suggest potential steps forward in research to advance clinical use and research on this topic.