Geotextiles have been widely promoted for pavement structures over the past 30 years. Previous studies show that a geotextile placed at the subgrade-base course interface of a paved road can increase the number of load repetitions before rutting failure. Thus, reduction of base and/or asphalt thickness may be possible. However, there is a lack of well-instrumented full-scale experiments to investigate effect of geotextile reinforcement on other possible mechanisms of pavement failure like fatigue of the Hot-Mix Asphalt (HMA) layer. In this study, full-scale accelerated pavement testing was done on eight pavement test sections. Six out of these eight sections had base layers reinforced with different types of woven geotextiles. The reinforced sections and the control sections (with unreinforced base) were paved with Superpave HMA layers. Base and subgrade materials were the same for all sections while some test sections had different asphalt and base layer thicknesses. Each test section was instrumented with six H-bar strain gages at the bottom of the HMA layers to measure longitudinal and transvers strains. The mechanistic response of each section was monitored and analysed at the selected number of wheel passes. Predicted fatigue lives of the test sections were calculated based on the Asphalt Institute and Shell models. Results indicate that fatigue life of test sections did not increase due to geotextile reinforcing although rutting performance of some reinforced sections did improve. This may indicate geotextiles may not improve fatigue performance of HMA layers in pavements.