With global climate and environment deterioration, the desertification is getting worse and the phenomenon of wind-sand flow frequently occurs in many areas. Hangers of suspension bridges may suffer the impact from wind-sand flow and be damaged. In this study, the riding-type hangers with four strands which are the commonly used hanger of long-span suspension bridges are taken as an example to investigate the influence of wind-sand flow on the hangers. The aerodynamic interference effect can occur among the four strands under the action of wind-sand flow. In order to explore the influence of wind-sand flow on the hangers, the wind-sand flow field around the riding-type hangers of a long-span suspension bridge is simulated within the FLUENT software on the basis of the numerical simulation of computational fluid dynamics. The pressure and velocity contour, aerostatic coefficients and forces produced by the wind-sand flow under different wind attack angle and volume fractions of sand phase are analyzed from the simulation. Results indicate that the forces exerted by the wind-sand flow on riding-type hangers are greater than the forces exerted only by wind. In the wind and wind-sand flow field, the drag and lift coefficients of the front two strands of hangers exhibit minor changes with increasing wind attack angle, whereas those of the back two strands increase first and then decrease to a small value. The volume fraction of the sand phase has an insignificant effect on the drag and lift coefficients, but has a significant effect on the force exerted on the hanger, and the force exerted on the hangers multiplies when the volume fraction of the sand phase multiplies. The results lay a theoretical foundation for the corrosion fatigue analysis of riding-type hangers for large-span suspension bridges under the action of wind-sand flow.