Objective: The aim of this study was to compare the patients who have antisocial personality disorder (ASPD) and the healthy individuals in terms of sexually transmitted diseases (STDs) and Blood-Borne Transmitted Infections (BTIs) prevalences. Methods: This study is a prospective, single-center, open-label, non-randomized controlled clinical study. There were two groups in the study. The patient group consistsed of 100 males who were diagnosed as ASPD with a clinical interview form. The control group consisted of 98 healthy males who did not have any psychiatric disorder. Dermatologic examination was performed, and clinical findings were recorded. Results: The mean age of the patient group was 21.96+/-2.40 (range 20-37) years. The mean age of the control group was 24.20+/-2.88 (21-36) years. The most common disease was gonorrhea (25%) followed by genital wart (11%), molluskum contagiosum (5%), HBsAg (4%), and HSV-2 seropositivity (4%) in the patients group. In the control group, HSV-2 seropositivity (4.08%), genital wart (3.06%), molluskum contagiosum (3.06%), and gonorrhe (1.02%) were commonly seen in the control group. STDs and/or BVTIs were found more common in the patients group (82%) than that in the control group (45.91%) (X-2=30.62, p=0.000). Conclusions: The patients with ASPD are at greater risk than normal population to catch a STDs or BTIs because of their lower educational levels and riskier behaviors. This condition entertains a risk in the general population and the patients themselves.