This article identifies the trends and impact of applying information and communication technologies (ICT) in the blended learning educational model, also known as blended learning, which proposes to make an integration between virtual and face-to-face oriented classes in classrooms. In this research, there are taken into account results and experiences in different educational areas, emphasizing mediation with ICT. Blended learning has achieved great impact thanks to the interaction between teachers and students, generating positive results in the teaching and learning process. The methodological aspects used with blended learning based on the use of ICT to develop both online and virtual activities allow the participant to develop cognitive, competitive, critical and constructive thinking skills for problem solving. Through this systematic review of literature, the importance of the use of ICT within this methodology is acknowledged, as it allows a dynamic and adjustable learning process, making it a pioneer in educational environments because of its great effectiveness and interaction.