ObjectiveIndividuals with anorexia nervosa (AN) restrict fat intake. The Geiselman Food Preference Questionnaire-I (c) (FPQ) is a validated self-report instrument that yields a fat preference score (>100=high fat preference, <100= low fat preference). The goal of the study was to assess the utility of the FPQ in patients with AN. Specific aims: (1) to examine change in fat preference scores before and after weight restoration in hospitalized patients; and (2) to compare patients' scores before and after weight restoration to scores from healthy participants (HPs). MethodThe FPQ was completed by 88 patients and 115 HPs. ResultsCompared with HPs, patients had significantly lower fat preference scores before (74.0332.03 vs. 102.93 +/- 16.89, P<0.001) and after (81.51 +/- 26.89 vs. 102.92 +/- 16.89, P<0.001) weight restoration. Fat preference scores increased with weight gain (74.03+32.03 vs. 81.51+26.89, P< 0.01) but did not normalize in AN. DiscussionAcutely weight restored patients continue to endorse decreased preference for high fat foods. The FPQ may be a useful metric by which to assess improvements in diet during treatment. Further study is warranted to validate the FPQ against observed food intake in AN. (c) 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2017; 50:148-151)