In order to study the dynamic responses of long-span suspension bridge with CFRP cables, a suspension bridge with CFRP cables which span of 896m is designed. The dynamic responses of suspension bridge with steel cables and CFRP cables are analyzed by ANSYS software, the effects of structural design parameters on the dynamic responses are investigated. The analysis results show the basic frequency of vertical, lateral bending and twist of suspension bridge with CFRP cables were increased in contrast with suspension bridge with steel cables, applying CFRP cable has little effect on the mode shapes and frequencies of horizontal bending and longitudinal floating of stiffening girder, the central buckle could improve the dynamic behavior of suspension bridge, the frequency not always increase with the stiffness of main cables increase, the stiffness of suspender have relatively little effect on the dynamic behavior of the entire suspension bridge.