Objective: Rapid development of economic construction that requires modern major engineering must implement synergetic management model. Not only does it increase the operation efficiency in major engineering works, it can also lower the risk in the engineering works and raise the management ability of the engineering team. Methods: the thesis in to optimize the coordinated management by considering stereoscopic structure in major projects, and through it to build a 3D Synergetic model. Results: This article establishes the 3D synergetic management model from information dimension, phase dimension and linkage dimension, which will be beneficial to enrich the theoretical connotation of major construction management and will provide maximum guarantee to the success of the construction. Conclusion: by testing the 3D Synergetic Management in Major Infrastructural Project, the thesis comes up with a 3D Synergetic Management, which enriches the theories of major projects.