In this paper, we conduct research on the project-driven alliance between the college and enterprise teaching mode and the applications on the contemporary vocational education. To achieve the aim of higher education popularization in our country, to vigorously develop vocational education is the important way. Higher vocational education for national and local economic development is the purpose of training the production, construction, management and service first line need to cultivate high quality personnel. Higher vocational education is the social demand as the primary guidance of employment education, cultivate the students should be a technology applied talents with skills. Our research proposes the novel guideline to deal with the mentioned issues which is applicable.