Unintended pregnancy continues to be a substantial public health problem. Emergency contraception (EC) provides a last chance at pregnancy prevention. Several safe and effective options for emergency contraception are currently available. The Yuzpe method, a combined hormonal regimen, was essentially replaced by other oral medications including levonorgestrel and the antiprogestin ulipristal. The antiprogestin mifepristone has been studied for use as emergency contraception. The most effective postcoital method of contraception is the copper intrauterine device (IUD). Obesity and the simultaneous initiation of progestin-containing contraception may decrease the effectiveness of some emergency contraception.