Cosmetopea regards on Fitchia nutans (asteraceae), an endemic plant previously used as a skin care ingredient included in a sacred traditional monai preparation in French Polynesia, led us to investigate its cosmetoceutical properties. An extract of leaves of F. nutans was submitted to anti-ageing activity assays using ex vivo human skin tests and evidenced its potential to stimulate collagens and elastin dermal growth. We report herein the first phytochemical study of this plant extract, showing that its main constituents are sesquiterpenoids (including a new natural product compound: 15-isovaleroyloxydihydrocostunolide), phenylpropanoids, and phenolic derivatives. (C) 2016 Academie des sciences. Published by Elsevier Masson SAS.