This paper describes a macromodel of operational amplifiers for compressor circuit design. The macromodel allows to simulate the operational amplifier with singlepower supply as well as double-power supply. The output waveforms using the macromodel are compared with those using the pre-set model only with double-power supply. The output voltages using the present macromodel are amplified in the region less than 200 mV input voltages and are compressed in the region larger than 200mV. On the other hand, the output voltages using the pre-set model are constantly amplified in the whole region. It has been found that the macromodel that can take into account the behavior of a single power supply is suitable in simulating of compressor circuits.