This paper presents HAMSTER, the HeAlthy, Mobility and Security based data communication archiTEctuRe. HAMSTER is designed for Unmanned Vehicles and addresses mainly three types of communications: machine-to-machine, machine-to-infrastructure and internal machine communications. It is divided into three main versions: Flying HAMSTER (for aerial systems), Running HAMSTER (for terrestrial systems) and Swimming HAMSTER (for aquatic systems). Every version of such architecture is also equipped with Sphere and Nimble. Sphere deals with Safety & Security aspects regarding communication, components "health" and modules authentication. Nimble is aimed at increasing the overall mobility in such scenarios, strongly actuating with inherent communications of each application field. This paper details every aspect of HAMSTER and presents, as a plus at the end, two case studies: the first one consists of an evaluation of five communications schemes for internal communications in airplanes; the second one is a cryptographic evaluation of two Elliptic Curve Cryptography algorithms.