The campus website is a comprehensive information platform of campus informatization. When using the algorithm design of campus information system, the key factors that are not designed to handle the campus information system, it has the problems of large error of system design. To this end, the design method of campus information system based on IOT technology is put forward. In this method, a higher vocational college as an example, the framework of college information system is given, and be divided into various forms of management informatization, teaching informatization and students network life style. On this basis, the concept of the Internet of things is described. And IOT technology is as the core technology of information integration, in which a variety of forms of information system available in schools are integrated, to give the unified data center, security authentication center, user privilege management center and user interface, and implement the design of campus information system. The experiments show that the design method of campus information system based on IOT technology provides a good basis for the realization of campus information construction.