Approximately one half of oncological patients worldwide use complementary, alternative and integrative methods. The state of evidence for the therapies used is very inhomogeneous. Integrative oncology can be understood as the combination of conventionally approved medicine (conventional and mainstream medicine), scientifically tested complementary medicine and mind body medicine. This article gives a brief survey of the state of the evidence as well as the fields of application of mind body medicine in integrative oncology. The efficacy of relaxation techniques for the reduction of anxiety and nausea and enhancement of quality of life is well documented (level of evidence 1a). Mindfulness-based stress reduction (MBSR) shows positive effects during and after primary therapy. Anxiety and stress are reduced and the quality of sleep and health-related quality of life (HrQoL) are enhanced. There is also good evidence for the positive effects of yoga on HrQoL for breast cancer patients. Qigong and Tai Chi are beneficial for the reduction of fatigue as well as improvement in sleep quality, vitality and HrQoL. Preoperative hypnosis can reduce doses of anesthetic drugs and alleviate pain, nausea and vomiting, fatigue and emotional strain. Many methods of mind body medicine have a good state of evidence. Particularly recommendable are (1) meditation and MBSR for enhancement of HrQoL, reduction of depression and a better general stress management, (2) relaxation training for the reduction of depressive symptoms, (3) yoga to combat depression, mood disturbances and fatigue, as well as (4) hypnosis to combat fatigue.