Nicotin Replacement Therapy (NRT) has been the preferred first option in smoking cessation treatment for many years. NRT reduces both the desire to smoke and the withdrawal symptoms. Nicotine gum addiction may rarely develop during NRT. In this study, we present a case who became addicted to nicotine gum for 18 years, was admitted to the smoking cessation polyclinic, and treated with bupropion. The aim of this case study is to highlight that bupropion is also an effective option to treat nicotine gum addiction, a rarely seen occurrence.