This paper presents a new version of Wheelchair. q, a wheelchair with stair climbing ability. The wheelchair is able to climb single obstacles or staircases thanks to a hybrid wheel-leg locomotion unit with a triple-wheels cluster architecture. The new concept presented in this work represents an improvement respect to previous versions. Through a different arrangement of functional elements, the wheelchair performances in terms of stability and regularity during movement on stair ha ve been increased. In particular, attention has been paid to ensure a regular and comfortable motion for the user during stair climbing operation. For this reason, a cam mechanism has been introduced and designed with the aim to compensate the oscillation generated on the wheelchair frame by the locomotion unit rotation. A design methodology for the cam profile is presented. Moreover, a parametric analysis on the cam profile and on the mechanism dimensions has been conducted with the aim to find a cam profile with suitable dimensions and performances in terms of pressure angle and radius of curvature. (C) 2017 Elsevier Ltd. All rights reserved.