The election of Donald Trump as the 45th U.S. President earmarks a new beginning of American domestic and foreign policies, to which his populist thinking and unconventional approach have caused great uncertainty. While recognizing the challenges that President Trump may bring to the world in general and China-U.S. relations in particular, the Chinese government under the core leadership of President Xi Jinping firmly believes in the world's general trend for sustained progress, remains committed to the track of win-win cooperation with other countries, and is adopting both reactive and proactive attitudes toward the great changes in global arenas while taking every precaution against the worst possible scenario. To better manage China-U.S>relations at this critical juncture of world development, it is imperative for both countries to adapt to various new changes, deepen their mutual understanding of each other's diplomatic philosophy, and continue sharing the dividends of peace and development. If the two countries can manage to pass the first few rounds of tests through more active conceptual matching-up and pragmatic cooperation, they will be in a better position to realize their respective national agendas of "rejuvenation of the Chinese nation" and "making America great again." Otherwise, both countries and even the whole world may fall into devastating confrontation and escalating conflicts.