This article presents a single-phase series active power filter for mitigation of the load voltage harmonic content while maintaining the voltage on the DC side regulated without the support of a voltage source. The proposed series active power filter control algorithm eliminates the additional voltage source to regulate the DC voltage, and with the adopted topology, a coupling transformer is not used to interface the series active power filter with the electrical power grid. The article describes the control strategy that encapsulates the grid synchronization scheme, compensation voltage calculation, damping algorithm, and dead-time compensation. The topology and control strategy of the series active power filter have been evaluated in simulation software, and simulations results are presented. Experimental results, obtained with a developed laboratorial prototype, validate the theoretical assumptions and are within the harmonic spectrum limits imposed by the international recommendations of IEEE Standard 519.