Stressmanagementskill trainingwas always been knowntoi be benif icial on depression, anxiety and stress. We applied the same in patients suffering fromtype-2 diabetes through quasi-experimental method following the pre and post test design method with a control group. Twenty diabetic patients (10 females, 10 males) were selected and randomly divide intotwogroups; testandcontrol (n=12 each) Levels of depression, anxiety and stress were measured by using depression, anxiety and stress questionnaire (Dass-21) in the pre-test phases which was followed by the stress reduction skill training conducted in 10 different sessions only for the test group. At the end of re-interventions, levels of depression, anxiety and stress of patientswere measured and the data were analyzed by using analysis of variance. Signif icant differences between levels of depression, anxiety and stress in two groups were found which was finally reduced in the test group by the stress management skill training. Conclusively, stress management skill could be an appropriate treatment method for improving mood disorders, inpatients suffering fromtype-2 diabetes.