The author analyzes the process of formation and development of research in the field of cybernetics. The 1950-1960s became a flourishing era for computer technology and the highest achievements in the scientific field of cybernetics in the USSR. Siberian Physical-Technical Institute (SPhTI) at Tomsk State University (TSU) became the Center of the formation and development of research in the field of cybernetics in the 1950s. in the east of the USSR. In the early 1950s at the department of radiophysics of TSU the associate professors F..P Tarasenko, G.A. Medvedev, senior research associates A.D. Zakrevsky and V.P. Tarasenko organized a group of young teachers and students of TSU and SPhTI. They decided to start the implementation of a major government topic - developing the applied issues of information theory and the development of electronic computers. Later that year the first computer in Siberia "Ural-1" set up in SPhTI marked the beginning of scientific school in the field of informatics. In the 1950s Tomsk Polytechnic Institute (TPI) implemented the research in the field of automation of particle accelerators, mathematical modeling and the use of computer technology, automation and optimization of systems organizational management of the university. In a short time the intense pace of research in the field of cybernetics turned Tomsk research and education complex into a research center in that on a national scale. The research in the field of cybernetics had important theoretical and practical significance. The studies developed into large schools of thought, conducted the research in the most promising areas of cybernetics. The employees SPhTI under A.D. Zakrevsky developed the logical representation language synthesis algorithms of discrete automata (LYaPAS) and its more sophisticated systems, as well as a number of automatic synthesis of digital machines for design and research organizations in the USSR. On the basis of LYaPAS-71 for the computer programming system of the 2nd generation was created, which anticipated numerous ideas that were developed abroad only by 3rd generation machines. The electron synchrotron "Sirius" designed and launched in 1965 by TPI's employees was the most powerful in the country and one of the largest in the world. The basic research in physics of the acceleration of charged particles, nuclear physics and elementary particle physics, solid state physics were conducted on 'Sitius'.