This paper presents a digital active electrode (DAE) system for multi-parameter biopotential signal acquisition in portable and wearable devices. It is built around an IC that performs analog signal processing and digitization with the help of on-chip instrumentation amplifiers, a 12 bit ADC and a digital interface. Via a standard (IC)-C-2 bus, up to 16 digital active electrodes (15-channels) can be connected to a commercially available microcontroller, thus significantly reducing system complexity and cost. In addition, the DAE utilizes an innovative functionally DC-coupled amplifier to preserve input DC signal, while still achieving state-of-the-art performance: 60 nV/sqrt(Hz) input-referred noise and +/- 350 mV electrode-offset tolerance. A common-mode feedforward scheme improves the CMRR of an AE pair from 40 dB to maximum 102 dB.