BACKGROUND According to the World Health Organization (WHO), adolescents are individuals aged between 10-19 years. In India, by 18 years 54% adolescents are married, 25-35% of adolescent girls of about 17 years of age begin child bearing and these adolescent pregnancies constitute 10-15% of total pregnancies. In India, although abortion is legal, unsafe abortions account for 50% of all maternal deaths of girls between 15 and 19 years. Most of the health problems in adolescents need personal, friendly, and confidential advices and reassurances from the medical personnel, to get clear insight into the health problems with a little medical intervention. Family Life Education for adolescents about current needs associated with changing physical, cognitive, social, emotional, and sexual developments promote them to fulfil their anticipatory or future family-related needs by preparing them for adult roles to meet responsibilities in marriage and parenting. Aim-To know the extent of improvement of knowledge on menstruation and menstrual hygiene practices amongst school going adolescent girls in a village in Krishna District after educational Intervention. Objective-To assess the basal knowledge about menstruation among school going adolescent girls and to assess the impact of Reproductive Health Education with a special emphasis on Nutrition and Reproductive Health. MATERIALS AND METHODS The study is done on 250 adolescent girls of Zilla Parishad High School of Nidamanuru village, coming under the Primary Health Centre area of Kankipadu, Krishna District Andhra Pradesh. RESULTS Interventional study was conducted among 250 adolescent high school girls. Out of 250 students, majority were in the age group of 13-14 years (76%). Two thirds of study subjects were Hindus. Majority of the study subjects belong to backward caste. Mothers of 35.38% and 32.05% girls had primary or secondary educational status. Majority (42.61%) of the study subjects belong to class IV, modified B. G. Prasad's socioeconomic status followed by class III (28.14%) followed by class II (24.3%). CONCLUSION Knowledge regarding various aspects of menstruation was poor before educational intervention which subsequently improved after providing health education. Therefore, family life education should be strictly implemented in the school and college curriculum with age appropriate topics which include package of information regarding small family norm, gender discrimination, domestic violence, nutrition, pubertal changes, menstrual hygiene, pregnancy, abortion, contraception, unsafe sex, HIV/AIDS, etc.