This study introduces a novel unified interface design (UID) concept to develop factory automation production manufacturing systems in the LCD industry. In response to the recent needs of smart factory production and integration of manufacturing information for the manufacturing sector, automation technology and systems play an increasingly important role in integrating production applications. The implementation of automation transportation system (ATS) also started off as single systems (material systems) and evolved to incorporate multiple applications and roles (material + information + intelligent management). Since upgrading manufacturing technology, developed UID innovative models integrate manufacturing engineering concepts that effectively integrated system of material and information flow. Therefore, the purpose of this study is to evaluate the innovative concepts used to implement ATS with UID concepts into integrated production engineering to effectively combine system material and information flow. Through the actual process allows us to identify critical elements that may be emulated or used as a reference for other similar companies or industries interested in developing UID while reducing the risks of failure.