The relay autotuner provides a simple way of finding PID controller parameters. Even though relay autotuning is much investigated in the literature, the practical aspects are not that well-documented. In this paper an asymmetric relay autotuner with features such as a startup procedure and adaptive relay amplitudes is proposed. Parameter choices and handling of noise, disturbances, start in non-steady state and other possible error sources are discussed. The autotuner is implemented and tested on an industrial air handling unit to show its use in practice. The experiments show good results, and prove that the proposed simple autotuner is well-suited for industrial use. But the experiments also enlighten possible error sources and remaining problems. (C) 2016 Elsevier Ltd. All rights reserved.