This paper mainly discusses the application of operational research models in Construction project management. Through quantifying the actual problems in the tender management, material procurement management and design management of construction management, apply the operational research models to obtain the optimal solution of the problem. And also discusses the development and improvement of operational research models in Construction project management. The innovation point of this article lies in the quantification of the practical problems in the management of construction projects, then use the mathematical model to solve the practical problems.