The field of immune-oncology is rapidly progressing with new data being generated across all research areas of this field. The American Association for Cancer Research (AACR)'s Tumor Immunology and Immunotherapy meeting, the sixth in this series, provides a forum for researchers from academia and industry, as well as clinicians, to present their work to a global audience to enhance the understanding of the immune response to cancer and to focus on how this response can be used for disease treatment and prevention.