The study sought to identify the influential factors of stereotypes, social distance, and prejudice toward racial/ethnic minorities in the United States. We used data from the American General Social Survey (GSS) of 2012, and analysed the data of 4 820 individuals (3 700 Caucasians, 722 African Americans, and 398 others; males = 44.2%, females = 55.8%). Data were analysed using the SPSS 18.0 Statistics Program. In order to test for differences in racial prejudice by demographic characteristics by stereotyping and social distancing, we utilised variance and regression analyses procedures. Results suggest that stereotypes and social distance effects on prejudice toward African Americans vary according to ethnicity, gender, age, education, and income. Specifically, older and less-educated white males were more prejudiced toward African Americans than were individuals from other sociodemographic groupings. There was a direct relationship between the holding of stereotypical views and social distance, in that those who showed higher levels of stereotyping maintained a greater social distance from African Americans and showed greater implicit prejudice toward them. Racism toward African Americans remains a major social concern in the USA, and is largely influenced by sociodemographic factors.