Based on NVIDIA's Pascal architecture and designed to handle the graphical demands of 4K gaming, the MSI GeForce GTX 1080 Ti Founders Edition Graphics Card provides major improvements in performance, memory bandwidth, and power efficiency over its predecessor, the high-performance Maxwell architecture. It also introduces innovative graphics features and technologies that redefine the computer as the platform for playing AAA games and taking full advantage of virtual reality via NVIDIA VRWorks.

The front panel of the card features a variety of outputs. There are three DisplayPort 1.4 outputs in addition to an HDMI 2.0b output. The GTX 1080 Ti is not just about high-resolution gaming. Computationally intensive programs can utilize the GPU's 3584 cores to accelerate tasks using CUDA or other APIs.

For cooling, MSI implemented NVIDIA's blower-style cooler with vapor chamber cooling technology. This cooling configuration is good for SLI or other configurations where space between computer components can be a concern.