Veteran St Kilda defender Sam Fisher has called time on a remarkable career spanning 13 seasons, announcing his retirement today.

Taken at pick No. 55 in the 2003 National Draft from West Adelaide, Fisher debuted against Fremantle in Round 7, 2004 and went on to play 228 games in the red, white and black.

Over 13 years, the 34-year-old lined up against some of the best forwards in the competition, receiving All-Australian honours in 2008 as well as winning the Trevor Barker Award in 2008 and 2011.

The St Kilda Life Member said he felt the time was right to hang up the boots and is looking forward to the next stage of his life.

"I've thoroughly enjoyed my time playing for St Kilda Football Club and I can retire knowing that I have given my all over the past 13 years," Fisher said.

"While it will be different supporting from the sidelines, I'm looking forward to seeing my teammates and coaches enjoy well-deserved success in the years to come.

"I don't think anyone imagines they'll play over 200 games but I'm so grateful to have had this experience and would like to thank St Kilda Football Club and the fans for their support over the years."

St Kilda Senior Coach Alan Richardson credited Fisher's service and said he can be proud of his impact both on and off the field.

"Sam arrived at the club before a lot of us, myself included, but he will also leave a legacy that will extend past many of our times at the club," Richardson said.

"While Sam's honours as an All-Australian, Trevor Barker Award Winner and International Rules player highlight the impact he's had on the field he's also taken the opportunity in the last few years to help and teach our young defenders.

"Sam's definitely made his mark on the club, we thank him for his remarkable service and wish him all the best for the future."

After a strong start to the season, a hamstring injury kept Fisher to 12 senior games in 2016, with his final appearance coming in the Saints' Round 23 triumph over Brisbane Lions.

Sam Fisher statistics

Drafted: No. 55, 2003 National Draft

Debut: Round 7, 2004

Matches: 228

Goals: 22

Finals: 13

Grand finals: 3

International Rules Series: 2006

All-Australian: 2008

Trevor Barker Award: 2008, 2011

St Kilda life membership: 2014