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Separate the colors of Skittles that you want to flavor the vodka with. Many people choose to leave out the green, which is lime if you're using original Skittles, and purple, which is grape in the original style, as they can create a weird taste combination or a less than appealing color for the final product. However, you can put them in if you want. If you don't mind mixed flavors, you can just skip this step altogether. Note that if you choose to mix the flavors together, you will create an unappetizing brownish color.